A hygienic insecticidal composition and use thereof

Abstract

The present application relates to a kind of insecticide compositions, specifically a sanitary insecticide composition and its application.The composition is component A and component B, wherein component A is a compound shown in formula I;component B is oxamyl, carbosulfan, propoxur or carbaryl;the synergistic effect of the insecticide composition of the present application is obtained at a certain ratio, and the knockdown and lethal effect are improved compared with single agent, which is suitable for preventing and treating sanitary pests such as mosquitoes, flies, fleas, ants, cockroaches, mites, wasps and bedbugs.

Description

TECHNICAL FIELD

[0001] The present application relates to an insecticidal composition, in particular a sanitary insecticidal composition and its application. BACKGROUND

[0002] The methoxy acrylate compound of formula I has been disclosed in some patents in terms of configuration, preparation method and application in controlling sanitary pests, but the application of the compound in combination has not been involved. Due to long-term use of pesticides, the sanitary pests have higher and higher resistance to organophosphorus, carbamate and pyrethroid insecticides, and in practical application, high-activity compounds are needed to improve the control effect and reduce the amount of pesticides. SUMMARY

[0003] The present application provides a sanitary insecticidal composition and its application to solve the problems in the prior art.

[0004] In order to achieve the above-mentioned purpose, the present application adopts the following technical scheme:

[0005] A sanitary insecticidal composition, the composition is composed of component A and component B, the component A is a compound shown in formula I; the component B is propoxur, carbosulfan, propargite or carbaryl;

[0006] Formula I:

[0007]

[0008] Preferably, the weight ratio of component A to component B in the composition is 10:1 to 1:20.

[0009] The weight ratio of component A to component B in the composition is 2:1 to 1:20.

[0010] An application of the sanitary insecticidal composition, the application of the sanitary insecticidal composition in controlling sanitary pests in a place where the sanitary pests exist.

[0011] The sanitary pests are one or more of mosquitoes, flies, fleas, ants, cockroaches, mites, wasps and bedbugs; the place where the sanitary pests exist is a hotel, an airplane, a school, a factory, a residence or a livestock habitat.

[0012] The sanitary pests are preferably Culex pipiens pallens, Culex quinquefasciatus, Culex tritaeniorhynchus, Aedes albopictus, Aedes aegypti, Anopheles sinensis, Armigeres subalbatus, Chironomus, Musca domestica, Muscina stabulans, Chrysomya megacephala, Lucilia sericata, Lucilia cuprina, Lucilia luciita, Fannia scalaris, Fannia canicularis, Blattella germanica, Periplaneta americana, Cimex lectularius, Pulex irritans, Ixodes persulcatus, Ixodes sinensis, Ixodes ricinus, Boophilus microplus, Tetranychus urticae, Sarcoptes scabiei, ants and wasps.

[0013] A sanitary insecticidal preparation, active ingredients and adjuvants, the active ingredients in the preparation are the composition, the composition accounts for 2% to 80% of the total weight of the insecticide group.

[0014] The preparation dosage form is emulsion, water emulsion, microemulsion, wettable powder, suspension, water dispersible granule, dry suspension or microcapsule suspension.

[0015] The adjuvant in the preparation is any one or more of dispersant, wetting agent, disintegrant, filler, antifreeze, thickening agent, preservative, defoamer, solvent, emulsifier, capsule forming material, organic amine and deionized water.

[0016] The sanitary insecticidal preparation, when the dosage form is emulsion, includes the following raw materials in percentage by weight: 1-20% of component A, 1-20% of component B, 5-30% of emulsifier, solvent to 100%.

[0017] The sanitary insecticidal preparation, when the dosage form is water emulsion, includes the following raw materials in percentage by weight: 1-15% of component A, 1-15% of component B, 5-20% of solvent, 6-20% of emulsifier, 3-8% of antifreeze, 0.1-1% of defoamer, deionized water to 100%.

[0018] The sanitary insecticidal preparation, when the dosage form is microemulsion, includes the following raw materials in percentage by weight: 1-15% of component A, 1-15% of component B, 3-30% of solvent, 10-35% of emulsifier, deionized water to 100%.

[0019] The sanitary insecticidal preparation, when the dosage form is wettable powder, includes the following raw materials in percentage by weight: 1-20% of component A, 1-50% of component B, 2-6% of wetting agent, 7-18% of dispersant, filler to 100%.

[0020] The sanitary insecticidal preparation, when the dosage form is suspension, includes the following raw materials in percentage by weight: 1-20% of component A, 1-20% of component B, 1-8% of wetting agent, 1-8% of dispersant, 3-7% of antifreeze, 0.3-2% of preservative, 0.1-1% of defoamer, 0.5-3% of thickening agent, deionized water to 100%.

[0021] The sanitary insecticidal preparation, when the dosage form is water dispersible granule, includes the following raw materials in percentage by weight: 1-20% of component A, 1-40% of component B, 2-12% of wetting agent, 5-18% of dispersant, 2-8% of disintegrant, filler to 100%.

[0022] When the health insecticidal preparation is in the form of dry suspension agent, the raw materials include the following components in the following weight percentages: 1-20% of component A, 1-40% of component B, 1-8% of wetting agent, 1-8% of dispersing agent, and fillers to make up to 100%.

[0023] When the health insecticidal preparation is in the form of microcapsule suspension agent, the raw materials include the following percentages: 1-20% of component A, 1-20% of component B, 1-5% of wetting agent, 1-10% of capsule-forming material, 1-8% of dispersing agent, 2-6% of antifreezing agent, 0.3-1% of preservative, 0.1-1% of defoaming agent, 0.5-2% of thickening agent, 0.1-5% of organic amine, and deionized water to make up to 100%.

[0024] The dispersing agent is selected from any one of the following: polycarboxylate, lignin sulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate, naphthalene sulfonate formaldehyde condensate sodium salt, non-ionic hydroxyl polyethylene oxide block copolymer, fatty amine polyoxyethylene ether, fatty acid polyoxyethylene ester, glycerol fatty acid ester polyoxyethylene ether, and a mixture of two or more thereof in any ratio.

[0025] The wetting agent is selected from any one of the following: naphthalene sulfonate, sodium dodecyl sulfate, Laikai powder BX, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylbenzene polyoxyethylene ether phosphate, phenylethyl phenol polyoxyethylene ether phosphate, alkyl sulfate, alkyl sulfonate, and dodecyl benzene sulfonic acid, and a mixture of two or more thereof in any ratio.

[0026] The disintegrating agent is selected from any one of the following: sodium chloride, ammonium sulfate, sodium carbonate, sodium bicarbonate, and sodium sulfate, and a mixture of two or more thereof in any ratio.

[0027] The filler is selected from any one of the following: kaolin, white carbon black, corn starch, attapulgite, calcium carbonate, light calcium, and diatomite, and a mixture of two or more thereof in any ratio.

[0028] The antifreezing agent is any one of the following: ethylene glycol, propylene glycol, glycerol, and urea, and a mixture of two or more thereof in any ratio.

[0029] The thickening agent is any one of the following: xanthan gum, hydroxyethyl cellulose, methyl cellulose, magnesium aluminum silicate, and organic bentonite, and a mixture of two or more thereof in any ratio.

[0030] The preservative is any one of the following: sodium benzoate, benzoic acid, potassium sorbate, and carboxin, and a mixture of two or more thereof in any ratio.

[0031] The defoaming agent is any one of silicone compound, silicone oil, C8-10 fatty alcohol compound, C10-20 saturated fatty acid compound, a mixture of two or more of them in any ratio.

[0032] The solvent is selected from 100# solvent oil, 150# solvent oil, 200# solvent oil, dimethylformamide, dimethylacetamide, xylene, N-methylpyrrolidone, turpentine, soybean oil, methyl oleate, corn oil, rapeseed oil, castor oil, C8-16 alkane solvent, a mixture of two or more of them in any ratio.

[0033] The C8-16 alkane solvent is selected from D60 (ExxonMobil Chemical Company), D80 (ExxonMobil Chemical Company), D100 (ExxonMobil Chemical Company), D110 (ExxonMobil Chemical Company), Isopar-E (ExxonMobil Chemical Company), Isopar-G (ExxonMobil Chemical Company), Isopar-H (ExxonMobil Chemical Company), Isopar-L (ExxonMobil Chemical Company), Isopar-M (ExxonMobil Chemical Company), quinane, undecane, dodecane, tridecane, tetradecane, pentadecane, hexadecane, heptadecane, octadecane, a mixture of two or more of them in any ratio.

[0034] The emulsifier is selected from calcium dodecylbenzenesulfonate, OP series phosphate ester, alkylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, Span series, Tween series, fatty alcohol polyoxyethylene ether, styryl phenol polyoxyethylene ether, styryl phenol polyoxyethylene ether phosphate ester, alkyl aryl polyoxyethylene ether polyoxypropylene ether, a mixture of two or more of them in any ratio.

[0035] The encapsulating material is selected from any one of diphenylmethane diisocyanate, toluene diisocyanate, a mixture of two in any ratio.

[0036] The organic amine is selected from any one of ethylenediamine, propylenediamine, butylenediamine, octylenediamine, diethylenetriamine, 1,6-hexanediamine, a mixture of two in any ratio.

[0037] The health insecticidal preparation is used to control health pests by retarding spraying: the health insecticidal preparation is diluted with water (50-1000 times) and sprayed on the surface of walls, doors, windows, ceilings, plants and household in the habitat of health pests. The applicable dosage forms are suspension concentrate, wettable powder, water dispersible granule, microcapsule suspension concentrate and dry suspension concentrate.

[0038] The health insecticidal preparation is used for preventing and treating health pests by spraying in space, and is diluted with water (5-200 times) and sprayed in space where the health pests exist by constant spraying, low volume spraying or ultra low volume spraying.

[0039] The present application has the following advantages:

[0040] The insecticidal composition of the present application uses the methoxy acrylate compound shown in formula I as one of the active ingredients, and is compounded with the carbamate insecticide with strong knockdown and lethal performance, so that the knockdown rate and the lethal rate can be significantly improved, the density of mosquitoes and flies can be quickly reduced, the resistance generation can be delayed, and the application frequency can be reduced. DETAILED DESCRIPTION

[0041] The specific embodiments of the technical scheme of the present application are described in detail below, but the present application is not limited to the following description. The present application is described below in combination with specific examples.

[0042] The insecticidal composition of the present application has a synergistic effect at a certain ratio, has higher activity than single component, can significantly improve the knockdown rate and the lethal rate, quickly reduce the density of mosquitoes and flies, delay the resistance generation, and reduce the application frequency.

[0043] In the following examples

[0044] The laboratory preparation method of the wettable powder is as follows: components A and B, wetting agent, dispersant, filler are added into a food processor and mixed uniformly, and then are crushed in an air flow crusher to obtain the wettable powder.

[0045] The laboratory preparation method of the suspension concentrate is as follows: the wetting agent, dispersant, antifreeze agent, preservative, defoaming agent and water are weighed according to the ratio, mixed uniformly in a beaker, and then components A and B are added into the beaker, and then are transferred to a sand mill, zirconium oxide beads are added into the sand mill, and are ground for 2-3 hours, the thickening agent is added and ground for 0.5 hours, so that the particle size D 95 is controlled to be less than 5 microns, the zirconium oxide beads are removed by filtration, and the suspension concentrate is obtained.

[0046] The laboratory preparation method of the water dispersible granule is as follows: components A and B, wetting agent, dispersant, disintegrating agent and filler are added into a food processor and mixed uniformly, and then are crushed in an air flow crusher, and then are mixed again in a food processor, and then are extruded and granulated by a granulator to obtain the water dispersible granule.

[0047] The laboratory preparation method of the dry suspension concentrate is as follows: the wetting agent, dispersant, filler and water are weighed according to the ratio, mixed uniformly in a beaker, and then components A and B are added into the beaker, and then are transferred to a sand mill, zirconium oxide beads are added into the sand mill, and are ground for 2-3 hours, so that the particle size D 95Control in 5 microns, remove zirconium oxide beads, the resulting material through the spray dryer drying, can be prepared.

[0048] The preparation method of emulsifiable concentrate: component A and component B are dissolved in solvent, emulsifier is added, and then mixed and dissolved under stirring to form a transparent liquid, thereby obtaining the emulsifiable concentrate.

[0049] The preparation method of emulsifiable concentrate: component A and component B are dissolved in solvent, emulsifier is added, and then mixed and dissolved under stirring to form a transparent liquid, thereby obtaining the emulsifiable concentrate.

[0050] The preparation method of microemulsion: after component A, component B, solvent and emulsifier are uniformly dissolved, deionized water is added to form a transparent liquid, thereby obtaining the microemulsion.

[0051] The preparation method of microcapsule suspension concentrate: component A, capsule-forming material and solvent are heated and dissolved to form an oil phase, which is then added to an aqueous phase under shearing, and sheared for 5 min; then organic amine is slowly added dropwise, and then incubated at a certain temperature, solidified, and then adjusted in pH; finally, deionized water is added to make up to 100 g, thereby obtaining the microcapsule suspension concentrate.

[0052] Preparation example 1: 1% component A·propoxur emulsifiable concentrate

[0053] Component A 0.5 g, propoxur 0.5 g, calcium dodecyl benzene sulfonate 5 g, castor oil polyoxyethylene ether 9 g, dimethylformamide 5 g, and 150# solvent oil are added to make up to 100 g, and the emulsifiable concentrate is prepared according to the above method.

[0054] Preparation example 2: 12% component A·propoxur emulsifiable concentrate

[0055] Component A 2 g, propoxur 10 g, calcium dodecyl benzene sulfonate 7 g, alkylphenol polyoxyethylene ether 10 g, N-methyl pyrrolidone 5 g, and 150# solvent oil are added to make up to 100 g, and the emulsifiable concentrate is prepared according to the above method.

[0056] Preparation example 3: 6% component A·fenoxycarb emulsifiable concentrate

[0057] Component A 1 g, fenoxycarb 5 g, Span 80 6 g, alkylphenol polyoxyethylene ether 8 g, dimethylformamide 5 g, and 150# solvent oil are added to make up to 100 g, and the emulsifiable concentrate is prepared according to the above method.

[0058] Preparation example 4: 16% component A·fenoxycarb emulsifiable concentrate

[0059] Component A 2g, carbosulfan 20g, calcium dodecylbenzenesulfonate 13g, castor oil polyoxyethylene ether 7g, N-methylpyrrolidone 5g, 150# solvent naphtha q.s. to 100g, emulsifiable concentrate was prepared according to the above method.

[0060] Formulation Example 5: 22% Component A · carbosulfan emulsifiable concentrate

[0061] Component A 2g, carbosulfan 20g, calcium dodecylbenzenesulfonate 13g, castor oil polyoxyethylene ether 7g, N-methylpyrrolidone 5g, 150# solvent naphtha q.s. to 100g, emulsifiable concentrate was prepared according to the above method.

[0062] Formulation Example 6: 10% Component A · propoxur emulsion in water

[0063] Component A 2g, propoxur 8g, calcium dodecylbenzenesulfonate 2g, castor oil polyoxyethylene ether 8g, styrylphenol polyoxyethylene ether 4g, n-butanol 2g, 100# solvent naphtha 15g, ethylene glycol 5g, silicone compound 0.5g, deionized water q.s. to 100g, emulsion in water was prepared according to the above method.

[0064] Formulation Example 7: 9% Component A · carbaryl microemulsion

[0065] Component A 6g, carbaryl 3g, castor oil polyoxyethylene ether 20g, styrylphenol polyoxyethylene ether phosphate 10g, 150# solvent naphtha 30g, deionized water q.s. to 100g, microemulsion was prepared according to the above method.

[0066] Formulation Example 8: 15% Component A · propoxur microemulsion

[0067] Component A 3g, propoxur 12g, castor oil polyoxyethylene ether 30g, 150# solvent naphtha 30g, deionized water q.s. to 100g, microemulsion was prepared according to the above method.

[0068] Formulation Example 9: 11% Component A · oxamyl emulsion in water

[0069] Component A 3g, oxamyl 8g, calcium dodecylbenzenesulfonate 2g, styrylphenol polyoxyethylene ether 10g, n-butanol 2g, 150# solvent naphtha 15g, ethylene glycol 5g, silicone compound 0.5g, deionized water q.s. to 100g, emulsion in water was prepared according to the above method.

[0070] Formulation Example 10: 14% Component A · carbosulfan emulsion in water

[0071] Component A 10 g, carbosulfan 10 g, calcium dodecylbenzenesulfonate 2 g, castor oil polyoxyethylene ether 9 g, n-butanol 2 g, 150# solvent oil 15 g, ethylene glycol 5 g, silicone compound 0.5 g, deionized water up to 100 g, and an aqueous emulsion was prepared by the above method.

[0072] Preparation Example 11: 20% component A · propoxur suspension

[0073] Component A 10 g, propoxur 10 g, sodium dodecyl sulfate 4 g, lignin sulfonate 6 g, propylene glycol 2 g, ethylene glycol 3 g, potassium sorbate 0.5 g, magnesium aluminum silicate 1 g, xanthan gum 0.3 g, silicone oil 0.2 g, deionized water up to 100 g. A suspension was prepared by the above method.

[0074] Preparation Example 12: 15% component A · oxamyl suspension

[0075] Component A 7 g, oxamyl 8 g, alkyl sulfate 6 g, alkyl sulfonate 2 g, polycarboxylate 3 g, lignin sulfonate 4 g, propylene glycol 1 g, urea 3 g, potassium sorbate 0.5 g, magnesium aluminum silicate 0.5 g, xanthan gum 0.4 g, silicone oil 0.2 g, deionized water up to 100 g. A suspension was prepared by the above method.

[0076] Preparation Example 13: 40% component A · propoxur suspension

[0077] Component A 20 g, propoxur 20 g, alkyl benzene polyoxyethylene ether phosphate 2 g, alkyl sulfonate 2 g, lignin sulfonate 4 g, glycerol 5 g, sodium benzoate 0.5 g, casein 0.3 g, magnesium aluminum silicate 0.5 g, xanthan gum 0.2 g, silicone oil 0.2 g, deionized water up to 100 g. A suspension was prepared by the above method.

[0078] Preparation Example 14: 60% component A · propoxur water dispersible granule

[0079] Component A 20 g, propoxur 40 g, alkyl sulfate 2 g, lignin sulfonate 5 g, naphthalene sulfonate formaldehyde condensate sodium salt 5 g, sodium sulfate 1 g, ammonium sulfate 3 g, corn starch up to 100 g. A water dispersible granule was prepared by the above method.

[0080] Preparation Example 15: 50% component A · oxamyl water dispersible granule

[0081] Component A 10 g, oxamyl 40 g, laka powder BX 8 g, sodium dodecyl sulfate 3 g, naphthalene sulfonate formaldehyde condensate sodium salt 10 g, ammonium sulfate 5 g, kaolin up to 100 g. A water dispersible granule was prepared by the above method.

[0082] Preparation Example 16: 60% component A · carbosulfan water dispersible granule

[0083] Component A 20 g, carbosulfan 40 g, sodium dodecyl sulfate 6 g, lignin sulfonate 8 g, naphthalene sulfonate formaldehyde condensate sodium salt 12 g, sodium sulfate 3 g, corn starch to 100 g. The water dispersible granule was prepared according to the above method.

[0084] Preparation Example 17: 50% component A · carbosulfan wettable powder

[0085] Component A 10 g, carbosulfan 40 g, alkyl sulfate 4 g, naphthalene sulfonate formaldehyde condensate sodium salt 6 g, lignin sulfonate 4 g, white carbon black 3 g, kaolin to 100 g. The wettable powder was prepared according to the above method.

[0086] Preparation Example 18: 30% component A · carbaryl wettable powder

[0087] Component A 10 g, carbaryl 20 g, alkyl sulfate 5 g, naphthalene sulfonate formaldehyde condensate sodium salt 10 g, fatty amine polyoxyethylene ether 2 g, white carbon black 3 g, kaolin to 100 g. The wettable powder was prepared according to the above method.

[0088] Preparation Example 19: 60% component A · propoxur dry suspension

[0089] Component A 20 g, propoxur 40 g, alkyl sulfate 5 g, polycarboxylate 5 g, naphthalene sulfonate formaldehyde condensate sodium salt 3 g, corn starch to 100 g. The dry suspension was prepared according to the above method.

[0090] Preparation Example 20: 10% component A · carbaryl microcapsule suspension

[0091] Component A 4 g, carbaryl 6 g, sodium dodecyl sulfate 2 g, non-ionic hydroxyl polyethylene oxide block copolymer 5 g, phenylethyl phenol polyoxyethylene ether phosphate 2 g and diphenyl methane diisocyanate 1 g were heated and dissolved, then added to 60 g of an aqueous solution containing 5% glycerol under shearing conditions, sheared for 5 min, slowly added 0.25 g of diethylenetriamine, then incubated at 50°C for 5 h, after the reaction was completed, the PH was adjusted to 4-6 with acetic acid, then 1 g of xanthan gum, 0.5 g of potassium sorbate and 0.5 g of silicone oil were added, and finally deionized water was added to 100 g, stirred uniformly, then the microcapsule suspension was prepared.

[0092] Comparative Example 1: 10% component A emulsion

[0093] Component A 10 g, calcium dodecylbenzenesulfonate 6 g, castor oil polyoxyethylene ether 8 g, 150# solvent oil to 100 g, emulsion was prepared according to the above method

[0094] Comparative Example 2: 10% propoxur emulsion

[0095] Chlorpyrifos 10 g, calcium dodecylbenzenesulfonate 6 g, castor oil polyoxyethylene ether 8 g, 150# solvent oil to 100 g, emulsifiable concentrate was prepared according to the above method

[0096] Comparative Example 3: 20% component A wettable powder

[0097] Component A 20 g, alkyl sulfate 5 g, naphthalene sulfonate formaldehyde condensate sodium salt 10 g, fatty amine polyoxyethylene ether 2 g, white carbon black 3 g, kaolin to 100 g. Wettable powder was prepared according to the above method.

[0098] Comparative Example 4: 20% chlorpyrifos wettable powder

[0099] Chlorpyrifos 20 g, alkyl sulfate 5 g, naphthalene sulfonate formaldehyde condensate sodium salt 10 g, fatty amine polyoxyethylene ether 2 g, white carbon black 3 g, kaolin to 100 g. Wettable powder was prepared according to the above method.

[0100] Control agent 1: 10% lambda-cyhalothrin wettable powder (commercially available)

[0101] Control agent 2: 5% tetramethrin · permethrin emulsion in water (commercially available)

[0102] Verification test 1: co-toxicity coefficient test

[0103] (1) Test object: Culex pipiens pallens, Musca domestica (laboratory breeding)

[0104] (2) Test method: Refer to GB / T26350-2010 "Fly resistance detection method housefly bioassay method" and NY / T1154.7-2006 "Pesticide indoor biological determination test guidelines insecticide part 7: mixed joint action determination"

[0105] (3) Data statistics: The test agent was first dissolved in dichloromethane, then serially diluted with an aqueous solution containing 0.1% Triton-X100 at a ratio of agent:aqueous solution of 1:9, 1 mL of each dilution was added to a 150 mL serum bottle, the serum bottle was constantly rotated to evenly distribute the liquid on the inner wall of the bottle, and was placed in a fume hood overnight to completely volatilize the organic solvent. The concentration interval of 100% mortality and 100% survival of the test agent was determined. Within this interval, an appropriate concentration was taken, serially diluted with an aqueous solution containing 0.1% Triton-X100. 1 mL of each dilution was added to a 150 mL serum bottle, the serum bottle was constantly rotated to evenly distribute the liquid on the inner wall of the bottle, and was placed in a fume hood overnight to completely volatilize the organic solvent. Then vaseline was applied to the neck of the serum bottle, 20 test insects were placed in each bottle, and the experiment was repeated 5 times. The corresponding solvent treatment was used as the control group. After 1 h, all test insects were transferred to clean containers for standard feeding, and the number of deaths was checked and counted after 24 h. Statistical analysis software SPSS was used for analysis, and the LC 50 and 95% confidence interval of each agent were calculated. The results are shown in the following table:

[0106] Table 1 Co-toxicity coefficients of component A and propoxur on Musca domestica

[0107]

[0108] From Table 1, it can be seen that when the complexing ratio of component A: propoxur is 10:1 to 1:20, the co-toxicity coefficient on Musca domestica is greater than 120, showing a synergistic effect, especially when the complexing ratio is 2:1 to 1:20, the co-toxicity coefficient on Musca domestica is greater than 150, showing a significant synergistic effect.

[0109] Table 2 Co-toxicity coefficients of component A and propoxur on Culex pipiens pallens

[0110]

[0111] From Table 2, it can be seen that when the complexing ratio of component A: propoxur is 10:1 to 1:20, the co-toxicity coefficient on Culex pipiens pallens is greater than 120, showing a synergistic effect, especially when the complexing ratio is 2:1 to 1:20, the co-toxicity coefficient on Culex pipiens pallens is greater than 150, showing a significant synergistic effect.

[0112] In addition, when the complexing ratio of component A and other component B is 2:1 to 1:20, there is also a similar synergistic effect on mosquitoes and flies.

[0113] Verification test 2: spray efficacy test for controlling mosquitoes and flies

[0114] (1) Test object: Culex pipiens pallens and Musca domestica (laboratory breeding)

[0115] (2) Test method: refer to GB / T 13917.1-2009 Pesticide Registration Indoor Efficacy Test and Evaluation of Hygienic Insecticide, spray test.

[0116] (3) Test agent: formulation examples 2, 3, 4, 5, 6, 7, 8, 9, 10 are diluted with water to 1000 ppm, comparative example 1, comparative example 2 and control agent 2 are diluted with water to 1000 ppm.

[0117] (4) Data statistics:

[0118] Table 3 efficacy test results of several treatments on Culex pipiens pallens and Musca domestica

[0119]

[0120] As shown in the above table 3, the efficacy of the formulation examples of the present application is better than the existing products on the market, and the combination of composition A and carbamate insecticide has a synergistic effect.

[0121] Verification test 3: retention efficacy test for controlling mosquitoes and flies

[0122] (1) Test object: Culex pipiens pallens and Musca domestica

[0123] (2) Test method: refer to GB / T 13917.1-2009 Pesticide Registration Indoor Efficacy Test and Evaluation of Hygienic Insecticide, retention spray test.

[0124] (3) Test agent: formulation examples 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 are diluted with water to 800 ppm, comparative example 3, comparative example 4 and control agent 1 are diluted with water to 800 ppm.

[0125] (4) Data statistics:

[0126] Table 4 efficacy test results of several treatments on Culex pipiens pallens and Musca domestica

[0127]

[0128]

[0129] As shown in the above table 3, the efficacy of the formulation examples of the present application is better than the existing products on the market, and the combination of composition A and carbamate insecticide has a synergistic effect.

[0130] The above examples are only to illustrate the technical concept and technical features of the present application, and cannot limit the protection scope of the present application. Any equivalent transformation or modification according to the essence of the present application should be covered within the protection scope of the present application.

Claims

1. A sanitary insecticidal composition, characterized by comprising, The composition is composed of component A and component B, wherein the component A is a compound shown in formula I; and the component B is propoxur. Formula I: The weight ratio of component A to component B in the composition is 10:1 to 1:

20.

2. The sanitary insecticidal composition according to claim 1, characterized in that, The weight ratio of component A to component B in the composition is 2:1 to 1:

20.

3. Use of a hygienic insecticidal composition according to claim 1, characterized in that, The application of the sanitary insecticidal composition in the prevention of sanitary pests in the habitat of the sanitary pests.

4. Use of a hygienic insecticidal composition according to claim 3, characterized in that, The sanitary pests are mosquitoes or flies; and the habitat of the sanitary pests is a hotel, an airplane, a school, a factory, a residential house or a livestock habitat.

5. A hygienic insecticidal preparation, the active ingredient and the adjuvant, characterized in that: The active ingredient in the preparation is the composition of claim 1, and the composition accounts for 2% to 80% of the total weight of the insecticide group.

6. The hygienic insecticidal preparation according to claim 5, characterized in that: The preparation is in the form of an emulsifiable concentrate, an aqueous emulsion, a microemulsion, a wettable powder, a suspension, a water dispersible granule, a dry suspension or a microcapsule suspension.

7. The hygienic insecticidal preparation according to claim 5 or 6, characterized in that: The adjuvant in the preparation is any one or more of a dispersant, a wetting agent, a disintegrating agent, a filler, an anti-freezing agent, a thickening agent, a preservative, an antifoaming agent, a solvent, an emulsifier, a capsule-forming material, an organic amine and deionized water.

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