Nondestructive testing equipment and method integrating microscopic fault CT (Computed Tomography) and Raman spectrum analysis

Abstract

The invention relates to non-destructive testing equipment and a non-destructive testing method integrating microscopic tomography CT and Raman spectrum analysis, belongs to the technical field of non-destructive testing of special biological resources, and solves the problem that the non-destructive testing of the special biological resources is difficult in the prior art. The non-destructive testing apparatus of the present invention comprises: a turntable; the X-ray imaging device is used for collecting a ray image of the target object; the ray protection mechanism is used for performing X-ray protection; the Raman spectrometer can be switched between a first position and a second position, and when the Raman spectrometer is located at the first position, Raman spectrum data of the target object are collected; when the Raman spectrometer is at the second position, the ray protection mechanism performs X-ray protection on the Raman spectrometer; and the rotating mechanism is used for driving the Raman spectrometer to rotate, so that the Raman spectrometer is switched between the first position and the second position. According to the invention, the X-ray microscopic tomography analysis technology and the Raman spectrum analysis technology are fused, and nondestructive testing can be carried out on special biological resources.

Description

Technical Field

[0001] The present invention relates to the technical field of nondestructive testing of special biological resources, and in particular to a nondestructive testing device and method integrating micro-tomography CT and Raman spectroscopy analysis. Background Art

[0002] Special biological resources include biological products, bacterial strains, human tissues, blood and blood products, etc. In view of the customs' requirements for non-destructive testing of special biological resources, there are currently no mature products to complete this task.

[0003] At present, the non-destructive testing of special biological resources in the customs clearance process is mainly achieved through computed tomography (CT). Computed tomography combines X-ray imaging and computer reconstruction technology. Through X-ray tomography analysis and reconstruction, the tissue structure of the material, as well as non-intrinsic characteristics such as atomic number and electron density can be obtained. Tomography is widely used in rapid non-destructive testing of passenger luggage, express parcels, etc. It can be used to quickly identify organic and inorganic substances, identify explosives, dangerous goods, and taxable goods such as milk powder and luxury goods. However, some products of special biological resources have a high degree of similarity in characteristics such as tissue structure, atomic number, and electron density, and it is difficult to show differences and distinguish and identify them.

[0004] Another non-destructive testing method is through Raman spectroscopy, which is based on the interaction between light and chemical bonds in materials. It can provide detailed information on the chemical structure, phase and morphology, crystallinity and molecular interactions of the sample to be tested. Raman spectroscopy is an intrinsic detection method, but this detection method has great restrictions on the container of the object to be tested. A transparent container must be used, otherwise it will affect the detection of the material in the container.

[0005] Tomography and Raman spectroscopy are two non-destructive testing technologies that each have their own advantages and disadvantages. Only one of them can not meet the needs of special biological resource testing. Summary of the invention

[0006] In view of the above analysis, the embodiments of the present invention aim to provide a non-destructive testing device and method integrating micro-tomography CT and Raman spectroscopy analysis, so as to solve the problem that the prior art is difficult to perform non-destructive testing on special biological resources.

[0007] On the one hand, an embodiment of the present invention provides a non-destructive testing device integrating micro-tomography CT and Raman spectroscopy analysis, the non-destructive testing device comprising:

[0008] A turntable for carrying the target object to be inspected;

[0009] An X-ray imaging device, used to collect a radiographic image of the target object;

[0010] Radiation protection mechanism, used for X-ray protection;

[0011] A Raman spectrometer, wherein the Raman spectrometer can be switched between a first position and a second position, wherein the Raman spectrometer collects Raman spectrum data of the target object when the Raman spectrometer is in the first position; and when the Raman spectrometer is in the second position, the radiation protection mechanism performs X-ray protection on the Raman spectrometer;

[0012] The rotating mechanism is used to drive the Raman spectrometer to rotate so as to switch between the first position and the second position.

[0013] Based on further improvements of the above-mentioned device, the radiation protection mechanism includes a protection chamber, the protection chamber and the Raman spectrometer are arranged on the same side of the turntable, a through hole is provided on the top surface of the protection chamber, and the Raman spectrometer enters the protection chamber through the through hole when moving from the first position to the second position.

[0014] Based on further improvement of the above device, the radiation protection mechanism also includes a protective cover plate, which is arranged on the outer side wall of the Raman spectrometer. When the Raman spectrometer is in the second position, the protective cover plate is tightly overlapped with the top surface of the protection chamber.

[0015] Based on the further improvement of the above-mentioned device, the top surface of the protective chamber includes a first step plane and a second step plane connected, the first step plane is higher than the second step plane, the Raman spectrometer is located above the first step plane when in the first position, the through hole is arranged on the second step plane, and when the Raman spectrometer is in the second position, the protective cover plate is tightly overlapped with the second step plane.

[0016] Based on the further improvement of the above equipment, the protection chamber and the protection cover are both made of lead plates.

[0017] Based on further improvement of the above-mentioned equipment, the nondestructive testing equipment further includes: a radiation protection shell, and the turntable, the X-ray imaging device, the radiation protection mechanism, the Raman spectrometer and the rotating mechanism are all arranged inside the radiation protection shell.

[0018] Based on the further improvement of the above equipment, the radiation protection shell is provided with a workpiece inlet and outlet, and an openable and closable protection door is provided at the workpiece inlet and outlet.

[0019] Based on further improvement of the above equipment, the radiation imaging device includes a radiation source and a detector, the radiation source and the detector are respectively arranged on two sides of the turntable, and the radiation source and the detector are arranged opposite to each other along a first direction.

[0020] On the other hand, the present invention also provides a nondestructive testing method integrating micro-tomography CT and Raman spectroscopy analysis. The nondestructive testing method detects whether there are special biological resources in the target object based on the nondestructive testing device as described above. The nondestructive testing method comprises the following steps:

[0021] Place the target object to be inspected on the turntable;

[0022] The Raman spectrometer is moved to a second position by the rotating mechanism, so that the radiation protection mechanism protects the Raman spectrometer;

[0023] Acquiring a radiographic image of the target object by means of the X-ray imaging device;

[0024] determining whether there is a target container in the target object according to the radiographic image;

[0025] If yes, taking out the target container from the target object, moving the Raman spectrometer to the first position by the rotating mechanism, collecting Raman spectrum data of the target container by the Raman spectrometer; judging whether there are special biological resources in the target container according to the Raman spectrum data;

[0026] If not, it is determined that there are no special biological resources in the target item and the detection is completed.

[0027] Based on a further improvement of the above method, the collecting of the radiographic image of the target object by the X-ray imaging device comprises the following steps:

[0028] The target object is rotated 360° by the turntable, and the X-ray device collects a series of projection images of the target object at different angles;

[0029] The projection image is reconstructed to obtain a three-dimensional radiographic image of the target object.

[0030] Compared with the prior art, the present invention can achieve at least one of the following beneficial effects:

[0031] 1. The present invention provides a multimodal nondestructive testing device and method for nondestructive testing of special biological resources, which integrates X-ray microtomography analysis technology and Raman spectroscopy analysis technology, and can obtain non-intrinsic characteristics such as equivalent atomic number, density, structural characteristics and intrinsic characteristics such as molecular structure of items, thereby realizing nondestructive testing of special biological resource items, and can be applied to customs or other special and important places.

[0032] 2. The nondestructive testing equipment of the present invention has two states: an X-ray testing state and a Raman spectrum testing state. The Raman spectrometer can be switched between a first position and a second position by setting a rotating mechanism. When performing Raman spectrum testing, the Raman spectrometer moves to the first position to collect Raman spectrum data of the target object on the turntable, and when performing X-ray testing, the Raman spectrometer moves to the second position, so that the radiation protection mechanism protects the Raman spectrometer from X-rays, thereby preventing the Raman spectrometer from being irradiated by X-rays.

[0033] 3. In the present invention, when detecting the target item, the X-ray image of the target item is first collected, and the target item is analyzed by using the strong penetration and non-destructive detection characteristics of the X-ray micro-tomography analysis technology to determine whether there is a target container in the target item. If there is a target container, the target item may contain special biological resources, thereby screening out items that may contain special biological resources, and then unpacking the items to take out the target container, collecting the Raman spectrum data of the target container for analysis, and determining whether there are special biological resources in the target container. In this way, the detection method of the present invention, by first performing X-ray micro-tomography analysis and then performing Raman spectrum analysis, can not only accurately identify and protect special biological resources, but also avoid damage to the items.

[0034] In the present invention, the above-mentioned technical solutions can also be combined with each other to achieve more preferred combination solutions. Other features and advantages of the present invention will be described in the subsequent description, and some advantages can become obvious from the description, or can be understood by practicing the present invention. The purpose and other advantages of the present invention can be realized and obtained through the contents particularly pointed out in the description and the drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] The drawings are only for the purpose of illustrating particular embodiments and are not to be considered limiting of the present invention. Like reference symbols denote like components throughout the drawings.

[0036] Figure 1 The structure of the nondestructive testing equipment of the embodiment of the present invention is shown in FIG. Figure 1 (Raman detection status);

[0037] Figure 2 The structure of the nondestructive testing equipment of the embodiment of the present invention is shown in FIG. Figure 2 (X-ray detection status).

[0038] Reference numerals:

[0039] 1- turntable; 2- ray source; 3- detector; 4- Raman spectrometer; 5- rotating mechanism;

[0040] 6-protection chamber; 7-protection cover; 8-radiation protection shell; 9-protection door. DETAILED DESCRIPTION

[0041] The preferred embodiments of the present invention are described in detail below in conjunction with the accompanying drawings, wherein the accompanying drawings constitute a part of this application and are used together with the embodiments of the present invention to illustrate the principles of the present invention, but are not used to limit the scope of the present invention.

[0042] One embodiment of the present invention discloses a nondestructive testing device integrating micro-tomography CT and Raman spectroscopy analysis, such as Figure 1-2 The nondestructive testing equipment includes:

[0043] Turntable 1, used for carrying the target object to be detected;

[0044] An X-ray imaging device, used to collect a radiographic image of the target object;

[0045] Radiation protection mechanism, used for X-ray protection;

[0046] A Raman spectrometer 4, wherein the Raman spectrometer 4 can be switched between a first position and a second position, wherein the Raman spectrometer 4 collects Raman spectrum data of the target object when the Raman spectrometer 4 is in the first position; and when the Raman spectrometer 4 is in the second position, the radiation protection mechanism performs X-ray protection on the Raman spectrometer 4;

[0047] The rotating mechanism 5 is used to drive the Raman spectrometer 4 to rotate so as to switch between the first position and the second position.

[0048] Compared with the prior art, the embodiments of the present invention provide a multimodal nondestructive testing device and method for nondestructive testing of special biological resources, which integrates X-ray microtomography analysis technology and Raman spectroscopy analysis technology, and can obtain non-intrinsic characteristics such as equivalent atomic number, density, structural characteristics and intrinsic characteristics such as molecular structure of the object, thereby realizing nondestructive testing of special biological resource items, and can be applied to customs or other special and important places.

[0049] Specifically, the nondestructive testing equipment of the embodiment of the present invention has two states: an X-ray detection state and a Raman spectrum detection state. The Raman spectrometer 4 can be switched between a first position and a second position by setting a rotating mechanism 5. When performing Raman spectrum detection, the Raman spectrometer 4 moves to the first position to collect Raman spectrum data of the target object on the turntable 1, and when performing X-ray detection, the Raman spectrometer 4 moves to the second position, so that the radiation protection mechanism performs X-ray protection on the Raman spectrometer 4, thereby preventing the Raman spectrometer 4 from being irradiated by X-rays.

[0050] In a specific embodiment, the radiation protection mechanism includes a protection chamber 6, and the protection chamber 6 and the Raman spectrometer 4 are arranged on the same side of the turntable 1. A through hole is provided on the top surface of the protection chamber 6, and the Raman spectrometer 4 enters the protection chamber 6 through the through hole when moving from the first position to the second position.

[0051] In this embodiment, a through hole is provided through the top surface of the protection chamber 6 , so that the Raman spectrometer 4 can directly enter the protection chamber 6 by moving.

[0052] During implementation, the rotating mechanism 5 is disposed in the protective chamber 6 , and one end of the Raman spectrometer 4 penetrates into the through hole and is connected to the rotating mechanism 5 .

[0053] Further specifically, the rotating mechanism 5 includes: a motor and a transmission shaft, the transmission shaft is arranged below the Raman spectrometer 4, one end of the Raman spectrometer 4 is inserted into the through hole and fixedly connected to the transmission shaft, the motor is arranged on one side of the transmission shaft, and the rotating shaft of the motor is connected to the connecting shaft through a chain or belt or gear to drive the Raman spectrometer 4 to rotate.

[0054] Specifically, the radiation protection mechanism further includes a protective cover plate 7 , which is disposed on the outer side wall of the Raman spectrometer 4 . When the Raman spectrometer 4 is in the second position, the protective cover plate 7 is tightly overlapped with the top surface of the protection chamber 6 .

[0055] In the embodiment of the present invention, by providing a protective cover plate 7 on the outer side wall of the Raman spectrometer 4, when the Raman spectrometer 4 moves to the second position, the Raman spectrometer 4 can be completely enclosed in the protective chamber 6, thereby improving the protective effect.

[0056] Preferably, the top surface of the protective chamber 6 includes a first step plane and a second step plane that are connected, the first step plane is higher than the second step plane, the Raman spectrometer 4 is located above the first step plane when it is in the first position, the through hole is arranged on the second step plane, and when the Raman spectrometer 4 is in the second position, the protective cover plate 7 is tightly overlapped with the second step plane.

[0057] The top surface of the protection chamber 6 is set to be stepped, so that the protection cover 7 can completely seal the through hole on the top surface of the protection chamber 6 .

[0058] Specifically, the protection chamber 6 and the protection cover plate 7 are both made of lead plates, which are widely used as X-ray shielding materials due to their high density and good attenuation ability for X-rays.

[0059] Specifically, the nondestructive testing equipment further includes: a radiation protection shell 8, and the turntable 1, the X-ray imaging device, the radiation protection mechanism, the Raman spectrometer 4 and the rotating mechanism 5 are all arranged inside the radiation protection shell 8. By providing the radiation protection shell 8, the operator and the surrounding environment can be protected from radiation damage, meeting the requirements of radiation safety and protection.

[0060] During implementation, the radiation protection shell 8 is a lead shell.

[0061] Specifically, the radiation protection shell 8 is provided with a workpiece inlet and outlet, and an openable and closable protection door 9 is provided at the workpiece inlet and outlet.

[0062] Specifically, the radiographic imaging device includes a ray source 2 and a detector 3, which are arranged on opposite sides of the turntable 1. The ray source 2 is used to emit X-rays that penetrate the object to be detected, and the detector 3 receives the X-rays that penetrate the object to be detected and generates an image based on the X-rays.

[0063] The embodiment of the present invention also provides a nondestructive testing method integrating micro-tomography CT and Raman spectroscopy analysis, wherein the nondestructive testing method uses the nondestructive testing device described above to detect whether there are special biological resources in the target object. The nondestructive testing method includes the following steps:

[0064] Placing the target object to be inspected on the turntable 1;

[0065] The Raman spectrometer 4 is moved to a second position by the rotating mechanism 5 so that the radiation protection mechanism protects the Raman spectrometer 4;

[0066] Acquiring a radiographic image of the target object by means of the X-ray imaging device;

[0067] determining whether there is a target container in the target object according to the radiographic image;

[0068] If yes, the target container is taken out from the target object, the Raman spectrometer 4 is moved to the first position by the rotating mechanism 5, and the Raman spectrometer 4 is used to collect Raman spectrum data of the target container; and it is determined whether there are special biological resources in the target container according to the Raman spectrum data;

[0069] If not, it is determined that there are no special biological resources in the target item and the detection is completed.

[0070] Compared with the prior art, in the embodiment of the present invention, when detecting the target item, the X-ray image of the target item is first collected, and the target item is analyzed by using the strong penetration and non-destructive detection characteristics of the X-ray micro-tomography analysis technology to determine whether there is a target container in the target item. If there is a target container, the target item may contain special biological resources, thereby screening out items that may contain special biological resources, and then unpacking the items to take out the target container, collecting the Raman spectrum data of the target container for analysis, and determining whether there are special biological resources in the container. In this way, the detection method of the present invention, by first performing X-ray micro-tomography analysis and then performing Raman spectrum analysis, can not only accurately identify and protect special biological resources, but also avoid damage to the items.

[0071] It should be noted that the embodiments of the present invention take into account that special biological resources generally require specific types of containers such as ampoules, cryopreservation tubes, glassware, etc. for storage. Therefore, by identifying whether there are the above-mentioned specific types of target containers in the target object, objects that may contain special biological resources can be screened out.

[0072] Specifically, collecting the radiographic image of the target object by the X-ray imaging device comprises the following steps:

[0073] The target object is rotated 360° by the turntable 1, and the X-ray device collects a series of projection images of the target object at different angles;

[0074] The projection image is reconstructed to obtain a three-dimensional radiographic image of the target object.

[0075] In the embodiment of the present invention, the detailed internal structure information of the target object can be obtained by using X-ray three-dimensional imaging technology, so that it can be accurately determined whether there is a target container in the target object.

[0076] During implementation, shape features in the radiographic image are acquired, and it is determined whether there is a target container in the target object based on the shape features.

[0077] Those skilled in the art will appreciate that all or part of the processes of the above-mentioned embodiments can be implemented by instructing related hardware through a computer program, and the program can be stored in a computer-readable storage medium, wherein the computer-readable storage medium is a disk, an optical disk, a read-only storage memory, or a random access memory, etc.

[0078] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any changes or substitutions that can be easily conceived by any technician familiar with the technical field within the technical scope disclosed by the present invention should be covered within the protection scope of the present invention.

Claims

1. A non-destructive testing device integrating micro-tomography CT and Raman spectroscopy, characterized in that: The non-destructive testing equipment includes: A turntable for carrying the target object to be inspected; An X-ray imaging device, used to collect a radiographic image of the target object; Radiation protection mechanism, used for X-ray protection; A Raman spectrometer, wherein the Raman spectrometer can be switched between a first position and a second position, wherein the Raman spectrometer collects Raman spectrum data of the target object when the Raman spectrometer is in the first position; and when the Raman spectrometer is in the second position, the radiation protection mechanism performs X-ray protection on the Raman spectrometer; The rotating mechanism is used to drive the Raman spectrometer to rotate so as to switch between the first position and the second position.

2. The nondestructive testing equipment according to claim 1, characterized in that: The radiation protection mechanism includes a protection chamber, the protection chamber and the Raman spectrometer are arranged on the same side of the turntable, a through hole is arranged on the top surface of the protection chamber, and the Raman spectrometer enters the protection chamber through the through hole when moving from the first position to the second position.

3. The nondestructive testing equipment according to claim 2, characterized in that: The radiation protection mechanism also includes a protection cover plate, which is arranged on the outer side wall of the Raman spectrometer. When the Raman spectrometer is in the second position, the protection cover plate is tightly overlapped with the top surface of the protection chamber.

4. The nondestructive testing equipment according to claim 3, characterized in that: The top surface of the protective chamber includes a first step plane and a second step plane connected to each other, the first step plane is higher than the second step plane, the Raman spectrometer is located above the first step plane when in the first position, the through hole is arranged on the second step plane, and when the Raman spectrometer is in the second position, the protective cover plate is tightly overlapped with the second step plane.

5. The nondestructive testing equipment according to claim 3, characterized in that: The protection chamber and the protection cover are both made of lead plates.

6. The nondestructive testing equipment according to any one of claims 1 to 5, characterized in that: The nondestructive testing equipment further comprises: a radiation protection shell, wherein the turntable, the X-ray imaging device, the radiation protection mechanism, the Raman spectrometer and the rotating mechanism are all arranged inside the radiation protection shell.

7. The nondestructive testing equipment according to claim 6, characterized in that: The radiation protection shell is provided with a workpiece inlet and outlet, and an openable and closable protection door is provided at the workpiece inlet and outlet.

8. The nondestructive testing equipment according to any one of claims 1 to 5, characterized in that: The radiation imaging device comprises a radiation source and a detector, wherein the radiation source and the detector are respectively arranged on two sides of the turntable, and the radiation source and the detector are arranged opposite to each other along a first direction.

9. A non-destructive testing method integrating micro-tomography CT and Raman spectroscopy, characterized in that: The nondestructive testing method is based on the nondestructive testing device described in any one of claims 1 to 8 to detect whether there are special biological resources in the target object, and the nondestructive testing method comprises the following steps: Place the target object to be inspected on the turntable; The Raman spectrometer is moved to a second position by the rotating mechanism, so that the radiation protection mechanism protects the Raman spectrometer; Acquiring a radiographic image of the target object by means of the X-ray imaging device; determining whether there is a target container in the target object according to the radiographic image; If yes, taking out the target container from the target object, moving the Raman spectrometer to the first position by the rotating mechanism, collecting Raman spectrum data of the target container by the Raman spectrometer; judging whether there are special biological resources in the target container according to the Raman spectrum data; If not, it is determined that there are no special biological resources in the target item and the detection is completed.

10. The nondestructive testing method according to claim 9, characterized in that: The step of collecting the radiographic image of the target object by the X-ray imaging device comprises the following steps: The target object is rotated 360° by the turntable, and the X-ray device collects a series of projection images of the target object at different angles; The projection image is reconstructed to obtain a three-dimensional radiographic image of the target object.

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