Atomization device

Abstract

The present invention relates to an atomization device comprising: a container assembly comprising a container and a sealing plug, the container having a first end and a second end; the piston assembly comprises a piston rod, a first piston and a second piston; in the containing cavity of the container, a first cavity is formed in the side, opposite to the sealing plug, of the second piston, and a second cavity is formed between the second piston and the sealing plug. The first chamber is used for accommodating a first raw material, and the second chamber is used for accommodating a second raw material; when the piston rod pushes the first piston to move relative to the second piston in the first direction, the first raw material enters the second cavity and is mixed with the second raw material to form a mixed material, and in the process, the sealing plug is separated from the first end under extrusion of the mixed material. The atomization device is simple and small in structure and easy and convenient to operate, waste of mixed materials can be reduced, the dosage is accurate, and the complete structure and the biological activity of the medicine can be kept in the delivery process.

Description

Technical Field

[0001] The present invention relates to the technical field of inhalation equipment, in particular to an atomizing device. Background Art

[0002] Nanobodies have a small molecular weight, stable structure, and strong tolerance, making them suitable for the development of multiple routes of administration, including intravenous injection, subcutaneous administration, oral administration, and aerosol inhalation. The inhalation administration of nanobodies can avoid the first-pass effect of oral administration, and has shown good efficacy in the treatment of lung diseases, and will have good application prospects in the treatment of respiratory and lung diseases.

[0003] Lyophilized powder is a common storage method for nanoantibodies. The powdered drug is stored in a vial and can be reconstituted by adding sterile water to obtain a reconstituted solution, which is then used for the administration process.

[0004] When using existing atomizers for drug administration, the reconstituted solution must first be added to an air compression or vibration atomizer. The atomizer can convert the antibody drug into mist or aerosol particles of appropriate size. The particle size distribution of the atomized particles will directly affect the subsequent inhalation and treatment effects. This atomization inhalation solution has the following disadvantages:

[0005] (1) The medication process is relatively complicated. The user is required to first reconstitute the powdered drug with sterile water, then add the reconstituted solution to the nebulizer, and then perform atomization inhalation. In addition, the reconstituted solution will come into direct contact with the air during the process of adding it to the nebulizer. Due to the introduction of new air, there is a risk of contamination.

[0006] (2) Air compression or vibration atomization devices are large in size and complex in structure. When atomizing a small dose of liquid medicine, the waste of liquid medicine is relatively serious, which affects the treatment effect.

[0007] (3) The physicochemical properties of nanoantibody drugs are relatively complex. They are administered through existing air compression or vibration atomization devices. This process requires the drug to be able to withstand the high pressure and force output by the atomization device and maintain the intact structure and biological activity of the drug during delivery. Summary of the invention

[0008] Based on the above-mentioned defects in the prior art, the purpose of the present invention is to provide a nebulizer with a simple and compact structure, easy to carry, few preparation steps, and easy operation. For small-dose nebulizer work, it can reduce the waste of mixed materials and make the dosage more accurate. For drugs with relatively complex physical and chemical properties, the complete structure and biological activity of the drugs can be maintained during the delivery process.

[0009] To this end, the present invention provides the following technical solutions.

[0010] The present invention provides an atomizing device, the atomizing device comprising:

[0011] A container assembly, comprising a container and a sealing plug, wherein the container has an open first end and a second end, and the sealing plug is used to seal the first end;

[0012] A piston assembly, comprising a piston rod, a first piston and a second piston, wherein the first piston and the second piston are sequentially arranged in the container along a first direction, and one end of the piston rod is located in the container and is linked to the first piston;

[0013] Wherein, in the cavity of the container, a first chamber is formed on the side of the second piston facing away from the sealing plug, and a second chamber is formed between the second piston and the sealing plug; the first chamber is used to contain a first raw material, and the second chamber is used to contain a second raw material;

[0014] When the piston rod pushes the first piston to move relative to the second piston in a first direction, the first raw material enters the second chamber and mixes with the second raw material to form a mixed material, and, in this process, the sealing plug is separated from the first end under the pressure of the mixed material.

[0015] Optionally, during the process of assembling the piston rod in the container, the piston rod pushes the first piston to move relative to the second piston in a first direction, so that the first raw material enters the second chamber.

[0016] Optionally, when the first piston moves along the first direction to abut against the second piston, the first raw material completely enters the second chamber.

[0017] Optionally, the first raw material is in liquid form, and the second raw material is in freeze-dried powder or liquid form.

[0018] Optionally, the second raw material is a nanobody in the form of a lyophilized powder.

[0019] Optionally, the sealing plug is a rubber plug.

[0020] Optionally, the inner wall of the container is provided with a groove, which forms a communication channel with the outer wall of the second piston, and the first chamber is connected with the second chamber through the communication channel;

[0021] Under the pressure of the first piston or under the action of the air pressure in the first chamber, the first raw material enters the second chamber through the connecting flow channel.

[0022] Optionally, the atomization device further comprises an atomization chip, which is located outside the sealing plug;

[0023] When the hydraulic pressure of the liquid flowing out of the first end reaches a preset value, the liquid is processed by the atomization chip to form atomized fine particles and then escapes.

[0024] Optionally, the sealing plug is disposed in the port of the first end and the two are interference fit.

[0025] Optionally, when the sealing plug is separated from the first end, the sealing plug abuts against the atomization chip under the pressure of the mixed material.

[0026] Optionally, the sealing plug comprises a sealing plug body and a plurality of protrusion structures, and the protrusion structures are arranged on a side of the sealing plug body facing the atomization chip;

[0027] When the sealing plug is separated from the first end, the protruding structure is used to form a first gap between the sealing plug body and the atomization chip, and the mixed material in the second chamber flows to the atomization flow channel of the atomization chip through the first gap.

[0028] Optionally, the atomization device further comprises a pen barrel, which is provided with a first hollow column and a second hollow column sequentially connected along a first direction; the container assembly and the piston assembly are both arranged in the pen barrel, and the atomization chip is installed in the second hollow column;

[0029] When the sealing plug is detached from the first end, the sealing plug body is located in the first hollow column, a second gap is formed between the circumferential surface wall of the sealing plug body and the inner wall of the first hollow column, and the second chamber, the second gap, the first gap and the atomization channel are connected in sequence.

[0030] Optionally, the lateral space dimension of the first hollow column is greater than the lateral space dimension of the second hollow column; when the sealing plug is detached from the first end, the protruding structure abuts against the end face of the second hollow column to reduce or completely avoid the covering of the atomization flow channel by the protruding structure.

[0031] Optionally, the sealing plug body comprises a first column and a second column sequentially connected along a first direction;

[0032] The first column is in a truncated cone shape and gradually expands along the first direction;

[0033] The second column is cylindrical, and its outer diameter is greater than or equal to the maximum outer diameter of the first column; when the sealing plug is assembled in the port of the first end, the outer wall of the second column is interference fit with the inner wall of the first end.

[0034] Optionally, the protruding structure partially protrudes outward from the circumferential surface wall of the second column;

[0035] When the sealing plug is assembled in the port of the first end, the protruding structure is squeezed by the inner wall of the first end and deformed.

[0036] Optionally, the atomization device further comprises a pen cover, wherein the pen cover is connected to the first end of the pen barrel;

[0037] The pen cap is provided with a sealing column, and the sealing column is inserted into the second hollow column and the two are interference fit to seal the first end of the pen barrel.

[0038] Optionally, the atomization device further comprises a pen cap connected to the second end of the pen barrel to seal the second end of the pen barrel.

[0039] Optionally, the atomization device further comprises a retaining member, which is used to retain the container and is installed in the pen barrel.

[0040] Optionally, the atomizing device further comprises a pen barrel and a trigger assembly, wherein the container assembly and the piston assembly are both arranged in the pen barrel; the trigger assembly comprises:

[0041] An operating mechanism, which is movably mounted on the pen barrel;

[0042] A ratchet pawl, which is rotatably connected to the operating mechanism, and the ratchet pawl is used to engage with a ratchet structure provided on the piston rod;

[0043] Wherein, when the operating mechanism moves in a first direction under an external force, the pawl pushes the ratchet structure to move the piston rod in the first direction, and the piston rod pushes the first piston and the second piston to move to trigger atomization;

[0044] When the operating mechanism moves along the second direction, the piston rod does not move along with it, and the first direction is opposite to the second direction.

[0045] Optionally, the operating mechanism is provided with a limiting structure, and the limiting structure is used to limit the rotation angle of the pawl, so that the pawl can remain engaged with the ratchet structure when the operating mechanism moves along the first direction.

[0046] Optionally, the operating mechanism includes:

[0047] An operating element, which is at least partially located outside the pen barrel;

[0048] A transfer element is located inside the pen barrel and connected to the operating element, and the pawl is rotatably connected to the transfer element.

[0049] Optionally, the atomization device further comprises a pen cap, which is connected to the second end of the pen barrel to seal the second end of the pen barrel;

[0050] The pen cap is provided with a limiting groove, and the piston rod is provided with a limiting protrusion; the limiting groove is engaged with the limiting protrusion to limit the piston rod from rotating relative to the pen cap.

[0051] Optionally, the pen cap is further provided with a receiving groove; when the atomization device is in an initial state, the ratchet structure is partially located in the receiving groove.

[0052] Optionally, the atomization device further comprises a pen cover, wherein the pen cover is connected to the first end of the pen barrel;

[0053] When assembling the atomizer device, the piston rod is assembled with the first piston and then pre-assembled with the pen cap to form a first pre-assembled component; the pen barrel and the pen cap are assembled and then pre-assembled with a container component to form a second pre-assembled component; then, the first pre-assembled component is assembled with the second pre-assembled component, and when the two are assembled, the pawl is engaged with the ratchet structure.

[0054] The present invention has the following technical effects:

[0055] The present invention provides an atomizing device, which can accommodate a first raw material and a second raw material respectively by configuring a first piston and a second piston in a container to form a first chamber and a second chamber. When a user needs to use the atomizing device, the first piston is driven to move by a piston rod, which can cause the first raw material to move to the second chamber and mix with the second raw material to achieve mixing of the two raw materials. There is no need for manual operation by the user to mix the two raw materials, fewer preparation steps, simplified operation steps, no new air is introduced in the process of mixing the first raw material and the second raw material, and the risk of pollution is reduced. The atomizing device has a simple and compact structure and is easy to carry. For small-dose atomization work, it can reduce the waste of mixed materials and make the dosage more accurate. In addition, the atomizing device of this solution provides power through a piston rod to achieve atomization, and the pressure on the output of the mixed material is relatively small. For drugs with relatively complex physical and chemical properties, the complete structure and biological activity of the drug can be maintained during the delivery process. BRIEF DESCRIPTION OF THE DRAWINGS

[0056] Figure 1 It is a structural cross-sectional view of the atomizing device of the present invention when it is in a non-atomizing state;

[0057] Figure 2 It is a structural cross-sectional view of the container assembly, the first piston and the second piston of the present invention when assembled;

[0058] Figure 3 for Figure 1 Enlarged view of point A in the middle;

[0059] Figure 4It is a structural cross-sectional view of the atomizing device of the present invention when it is in a primary atomizing process;

[0060] Figure 5 It is a structural cross-sectional view of the atomizing device of the present invention when atomization is completed once;

[0061] Figure 6 It is a structural explosion diagram of the atomizing device of the present invention;

[0062] Figure 7 Schematic diagram of the three-dimensional structure of the sealing plug of the present invention Figure 1 ;

[0063] Figure 8 Schematic diagram of the three-dimensional structure of the sealing plug of the present invention Figure 2 ;

[0064] Fig. 9 It is a schematic diagram of the three-dimensional structure of the piston rod of the present invention;

[0065] Fig.10 It is a schematic diagram of the three-dimensional structure of the pen cap of the present invention;

[0066] Fig.11 It is a schematic diagram of the three-dimensional structure of the pen holder of the present invention;

[0067] Fig.12 It is a schematic diagram of the three-dimensional structure of the pen cap of the present invention;

[0068] Fig.13 It is a schematic diagram of the three-dimensional structure of the atomization device of the present invention.

[0069] Description of Reference Numerals

[0070] 100. Atomizing device;

[0071] 1. Container assembly; 11. Container; 111. First end; 112. Second end; 113. Groove; 12. Sealing plug; 121. Sealing plug body; 1211. First column; 1212. Second column; 122. Protruding structure; 13. Bottle cap;

[0072] 2. Piston assembly; 21. Piston rod; 211. Ratchet structure; 212. Limiting protrusion; 213. Clamping portion; 22. First piston; 221. Clamping groove; 23. Second piston;

[0073] 31. First chamber; 32. Second chamber;

[0074] 4. Atomization chip; 41. Atomization flow channel;

[0075] 51, first gap; 52, second gap;

[0076] 61, pen holder; 611, first hollow column; 612, second hollow column; 6121, end surface; 613, buckle protrusion; 614, external thread; 615, long hole; 616, mounting hole;

[0077] 62, pen cap; 621, sealing column; 622, buckle groove; 623, sliding groove;

[0078] 63, pen cap; 631, limiting groove; 632, receiving groove; 633, internal thread;

[0079] 7. Retaining parts;

[0080] 8. trigger assembly; 81. operating mechanism; 811. operating element; 8111. connecting block; 812. switching element; 8121. limiting structure; 82. ratchet; 83. pivot shaft;

[0081] 9. Visual window. DETAILED DESCRIPTION

[0082] In order to make the technical solutions and beneficial effects of the present invention more clearly understood, the following is a detailed description by listing specific embodiments. Unless otherwise defined, the technical and scientific terms used herein have the same meanings as those in the technical field to which this application belongs.

[0083] In the description of the present invention, unless otherwise explicitly defined, terms such as “center”, “longitudinal”, “lateral”, “length”, “width”, “thickness”, “height”, “up”, “down”, “front”, “back”, “left”, “right”, “vertical”, “horizontal”, “top”, “bottom”, “inside”, “outside”, “clockwise”, “counterclockwise”, etc., indicating directions or positional relationships are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of simplified description of the present invention, and do not indicate that the referred device or element must have a specific direction, be constructed and operated in a specific direction, and should not be understood as a limitation on the present invention.

[0084] In the present invention, the terms "first" and "second" are only used for the purpose of clear description and cannot be understood as the relative importance of the indicated features or the number of the indicated technical features. Therefore, the features defined as "first" and "second" can explicitly include at least one of the features. In the description of the present invention, "multiple" means at least two; "several" means at least one, unless otherwise clearly defined.

[0085] In the present invention, unless otherwise clearly defined, the terms "install", "connect", "connect", "fix", "set", etc. should be understood in a broad sense. For example, "connection" can be a fixed connection, a detachable connection, or an integral molding; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0086] In the present invention, unless otherwise clearly defined, a first feature being “on”, “above”, “above”, “below”, “below”, “below” or “below” a second feature may mean that the first feature is in direct contact with the second feature, or the first feature and the second feature are in indirect contact with each other through an intermediate medium. Moreover, a first feature being “on”, “above” or “above” a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the horizontal height of the first feature is higher than the horizontal height of the second feature. A first feature being “below”, “below” or “below” a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the horizontal height of the first feature is lower than the horizontal height of the second feature.

[0087] The "first direction a" and "second direction b" mentioned in the present invention are both Figure 1 and Figure 2 The markings in shall prevail.

[0088] According to the following Figures 1 to 13 The atomizing device of the present invention is described in detail.

[0089] In this embodiment, if Figure 1 and Figure 2 As shown, the atomizing device 100 includes a container assembly 1 and a piston assembly 2. The container assembly 1 includes a container 11 and a sealing plug 12. The container 11 (such as a cartridge bottle) has an open first end 111 and a second end 112. The sealing plug 12 is used to seal the first end 111. The container 11 and the sealing plug 12 can be used to hold raw materials after being assembled. The piston assembly 2 includes a piston rod 21, a first piston 22, and a second piston 23. The first piston 22 and the second piston 23 are sequentially arranged in the container 11 along a first direction a. One end of the piston rod 21 is located in the container 11 and is linked to the first piston 22.

[0090] When the second piston 23 is assembled in the container 11, in the cavity of the container 11, the side of the second piston 23 facing away from the sealing plug 12 forms a first chamber 31, and a second chamber 32 is formed between the second piston 23 and the sealing plug 12. The first chamber 31 is used to accommodate the first raw material, and the second chamber 32 is used to accommodate the second raw material. When the piston rod 21 pushes the first piston 22 to move relative to the second piston 23 in the container 11 along the first direction a, the first raw material enters the second chamber 32 under the pressure of the first piston 22 or under the action of the air pressure of the first chamber 31 and mixes with the second raw material to form a mixed material. In addition, in the process of the first raw material entering the second chamber 32 or when the first raw material completely enters the second chamber 32, the sealing plug 12 is separated from the first end 111 under the pressure of the mixed material. When the first raw material and the second raw material are mixed, the user can use the atomization device for inhalation, and the piston rod 21 pushes the first piston 22 and the second piston 23 to move, so as to achieve atomization.

[0091] It should be understood that since the first piston 22 and the second piston 23 need to be installed from the second end 112 of the container 11, the second end 112 is relatively open, resulting in a gap between the inner wall of the second end 112 of the container 11 and the piston rod 21. Therefore, when the first chamber 31 is not yet closed by the first piston 22, it is necessary to place the second end 112 of the container 11 upward to prevent the first raw material in the first chamber 31 from spilling out from the second end 112. When the first piston 22 is installed in the container 11, the placement direction of the container 11 is not restricted. Of course, a plug can also be arranged at the second end 112 of the container 11 to prevent the first raw material in the first chamber 31 from spilling out from the second end 112, and the placement direction of the container 11 is not restricted. When the piston rod 21 needs to be assembled, the plug can be removed.

[0092] In the above technical solution, by configuring the first piston 22 and the second piston 23 in the container 11, and forming the first chamber 31 and the second chamber 32, the first raw material and the second raw material can be accommodated respectively. When the user needs to use the atomizer, the first piston 22 is first driven by the piston rod 21 to move relative to the second piston 23, which can cause the first raw material to move to the second chamber 32 and mix with the second raw material to achieve the mixing of the two raw materials. Then, the user can use the atomizer 100 for atomization inhalation. Compared with the technical solution of using air compression or vibration atomizer in the prior art, this solution does not require manual operation by the user to mix the two raw materials, has fewer preparation steps, simplifies the operation steps, does not introduce new air in the process of mixing the first raw material and the second raw material, reduces the risk of pollution, and the atomizer of this solution has a simple and compact structure and is easy to carry. For small-dose atomization work, it can reduce the waste of mixed materials (such as liquid medicine) and the dosage is more accurate. In addition, the atomization device of the present invention is powered by the piston rod 21 to achieve atomization, and the pressure on the output of the mixed material is relatively small. For drugs with relatively complex physical and chemical properties (such as nano-antibody drugs), the complete structure and biological activity of the drug are maintained during the delivery process.

[0093] In one embodiment, if Figure 1 and Figure 2 As shown, during the process of assembling the piston rod 21 in the container 11, the piston rod 21 pushes the first piston 22 to move relative to the second piston 23 along the first direction a, so that the first raw material enters the second chamber 32, that is, during the process of assembling the atomizing device 100, the first raw material and the second raw material are mixed, and the operation is convenient. Among them, regarding the linkage between the piston rod 21 and the first piston 22, it can be that the first piston 22 is first linked with the piston rod 21, and then the first piston 22 is assembled with the container 11 together with the piston rod 21, so that during the process of inserting the piston rod 21 and the first piston 22 into the container 11, the first raw material in the first chamber 31 moves to the second chamber 32; of course, it can also be that the first piston 22 is first loaded into the container 11, and then the piston rod 21 is inserted into the container 11, and the piston rod 21 completes the linkage with the first piston 22 during the insertion process.

[0094] In one embodiment, if Figure 1 , Figure 2 , Figure 6 and Fig. 9 As shown, one end of the piston rod 21 is provided with a clamping portion 213, and the first piston 22 is provided with a clamping groove 221, and the clamping portion 213 and the clamping groove 221 are mutually clamped to link the piston rod 21 and the first piston 22. When assembling the atomizing device 100, the piston rod 21 and the first piston 22 are assembled first, and then assembled with the container 11.

[0095] In one embodiment, if Figure 1 and Figure 2 As shown, when the first piston 22 moves along the first direction a until it abuts against the second piston 23, the first raw material completely enters the second chamber 32. In this way, when atomization inhalation is required, when the piston rod 21 pushes the first piston 22 to move along the first direction a, it can immediately push the second piston 23 to move synchronously, so that atomization can be quickly achieved. Of course, when the first raw material completely enters the second chamber 32, a gap can also be left between the first piston 22 and the second piston 23. In this way, when atomization inhalation is required, the piston rod 21 pushes the first piston 22 to move along the first direction a until it contacts the second piston 23, and then pushes the second piston 23 to move synchronously.

[0096] In one embodiment, the first raw material is in liquid form, which may be a medicinal solution or sterile water for injection, and the second raw material is in freeze-dried powder or liquid form. The liquid first raw material can more easily flow from the first chamber 31 into the second chamber 32 .

[0097] Furthermore, the second raw material is a nano antibody in the form of a freeze-dried powder. At present, the atomization supply method of nano antibodies is mainly to use an air compression or vibration atomization device, or to inhale in the form of dry powder. The atomization device of this scheme is used for the atomization of nano antibodies in the form of freeze-dried powder. Compared with the use of air compression or vibration atomization devices, there are fewer preparation steps, simplified operation steps, reduced contamination risks, more accurate dosage, and the intact structure and biological activity of the drug are maintained during the delivery process; compared with inhalation in the form of dry powder, the atomization device of this scheme inhales in the form of atomized fine particles, with a lower flow rate and higher comfort.

[0098] In one embodiment, the sealing plug 12 is a rubber plug with a simple structure, good sealing performance and elasticity.

[0099] In one embodiment, if Figure 2 As shown, the inner wall of the container 11 is provided with a groove 113, and a connecting flow channel is formed between the groove 113 and the outer wall of the second piston 23, and the first chamber 31 and the second chamber 32 are connected through the connecting flow channel. Under the extrusion of the first piston 22 or under the action of the air pressure of the first chamber 31, the first raw material enters the second chamber 32 through the connecting flow channel. Among them, the number of grooves 113 can be one or more. Preferably, in order to speed up the mixing speed of the first raw material and the second raw material, the number of grooves 113 is at least two. Further, in order to facilitate the first raw material to move uniformly to the second chamber 32, so as to facilitate the uniform mixing of the first raw material and the second raw material, all the grooves 113 are evenly spaced and distributed along the circumference of the container 11. In addition, in order to reduce the existence of dead corners on the inner wall of the container 11, the inner wall of the container 11 is cylindrical.

[0100] In one embodiment, if Figure 1 and Figure 3 As shown, the atomization device 100 also includes an atomization chip 4, which is provided with a plurality of atomization channels 41. The atomization chip 4 is located on the outside of the sealing plug 12. When the hydraulic pressure of the liquid flowing out of the first end 111 reaches a preset value, the liquid is processed by the atomization chip 4 to form atomized fine particles and then escapes. In this way, during the mixing of the first raw material and the second raw material, if the sealing plug 12 is separated from the first end 111, since the hydraulic pressure in the second chamber 32 has not reached the preset value at this time, the liquid cannot pass through the atomization channel 41 of the atomization chip 4, so as to avoid atomization during the mixing of the raw materials, thereby causing material waste.

[0101] Furthermore, if Figure 2 As shown, the sealing plug 12 is disposed in the port of the first end 111 , and the sealing plug 12 is interference fit with the inner wall of the first end 111 to ensure sealing.

[0102] Furthermore, if Figure 2 and Figure 3 As shown, when the sealing plug 12 is separated from the first end 111 , the sealing plug 12 abuts against the atomization chip 4 under the pressure of the mixed material.

[0103] In one embodiment, if Figure 3 , Figure 7 and Figure 8 As shown, the sealing plug 12 includes a sealing plug body 121 and four protruding structures 122, and the protruding structures 122 are arranged on one side of the sealing plug body 121 facing the atomization chip 4. Figure 1 and Figure 3 As shown, when the sealing plug 12 is separated from the first end 111, the protruding structure 122 is used to form a first gap 51 between the sealing plug body 121 and the atomizing chip 4, so as to prevent the sealing plug body 121 from covering the atomizing flow channel 41 of the atomizing chip 4, and ensure that the mixed material in the second chamber 32 can smoothly flow to the atomizing flow channel 41 of the atomizing chip 4 through the first gap 51, and be smoothly atomized. Of course, the number of the protruding structures 122 can also be one, two, three or even more.

[0104] Furthermore, if Figure 1 , Figure 3 , Figure 6 and Fig.13 As shown, the atomizing device 100 further includes a pen barrel 61, which is used for a user to hold. The container assembly 1 and the piston assembly 2 are both arranged in the pen barrel 61. The pen barrel 61 is provided with a first hollow column 611 and a second hollow column 612 connected in sequence along a first direction a, and the atomizing chip 4 is installed in the second hollow column 612. Figure 3As shown, when the sealing plug 12 is separated from the first end 111, the sealing plug body 121 is located in the first hollow column 611, and a second gap 52 is formed between the circumferential surface wall of the sealing plug body 121 and the inner wall of the first hollow column 611. The second chamber 32, the second gap 52, the first gap 51 and the atomizing flow channel 41 are connected in sequence, so that when atomization is performed, the mixed material in the second chamber 32 passes through the second gap 52 and the first gap 51 in sequence and then flows to the atomizing flow channel 41 to achieve atomization. In addition, the second hollow column 612 of this solution can also be adapted to be used with a nozzle assembly (not shown in the figure) for oral inhalation or nasal inhalation by the user, so that more atomized fine particles can be delivered to the human body, avoiding waste of atomized fine particles due to excessive exposure.

[0105] Furthermore, if Figure 3 As shown, the lateral space dimension of the first hollow column 611 is greater than the lateral space dimension of the second hollow column 612. When the sealing plug 12 is separated from the first end 111, the protruding structure 122 abuts against the end surface 6121 of the second hollow column 612 facing the first hollow column 611, so as to reduce or avoid direct contact between the protruding structure 122 and the surface of the atomization chip 4, that is, it is possible to reduce or completely avoid the covering of the atomization flow channel 41 by the protruding structure 122, and avoid the protruding structure 122 interfering with the atomization work.

[0106] In one embodiment, if Figure 7 and Figure 8 As shown, the sealing plug body 121 includes a first column 1211 and a second column 1212 connected in sequence along a first direction a. The first column 1211 is truncated cone-shaped and gradually expands along the first direction a. The second column 1212 is cylindrical, and the outer diameter of the second column 1212 is equal to the maximum outer diameter of the first column 1211. In this way, the connection between the first column 1211 and the second column 1212 is smooth. Of course, the outer diameter of the second column 1212 can also be greater than the maximum outer diameter of the first column 1211. Figure 2 and Figure 7 As shown, when the sealing plug 12 is assembled in the port of the first end 111, the outer wall of the second column 1212 is interference fit with the inner wall of the first end 111. Figure 3 and Figure 7 As shown, when the sealing plug 12 is separated from the first end 111, the circumferential outer wall of the first column 1211 is arranged as an inclined surface, which is beneficial to increase the flow of the mixed material in the second chamber 32 into the second gap 52, thereby facilitating the acceleration of atomization.

[0107] Furthermore, if Figure 7 and Figure 8 As shown, the protruding structure 122 partially protrudes outward from the circumferential surface wall of the second column 1212, which is beneficial to increase the lateral size of the protruding structure 122. Figure 3 As shown, the contact area between the protruding structure 122 and the end surface 6121 of the first hollow column 611 can be increased. Figure 2 As shown, when the sealing plug 12 is assembled in the port of the first end 111 , the protruding structure 122 is squeezed by the inner wall of the first end 111 and deformed to ensure that the sealing plug 12 can be smoothly snapped into the first end 111 of the container 11 .

[0108] In one embodiment, since the mixed material contacts the sealing plug 12 during the atomization process of the atomization device 100, in order to ensure the hygienic safety of the atomization inhalation, Figure 2 As shown, the container assembly 1 also includes a bottle cap 13, which is disposed on the first end 111 of the container 11 to cover the sealing plug 12 to prevent the sealing plug 12 from being contaminated during storage or transportation of the container assembly 1. When the container assembly 1 needs to be assembled in the pen holder 61, the bottle cap 13 is first removed and then assembled.

[0109] In one embodiment, if Figure 1 , Figure 6 and Fig.13 As shown, the atomizing device 100 further includes a pen cover 62, and the pen cover 62 is connected to the first end of the pen barrel 61. Figure 1 and Figure 3 As shown, the pen cap 62 is provided with a sealing column 621, which is inserted into the second hollow column 612 and the two are interference fit to seal the first end of the pen barrel 61. When the atomizing device 100 is not needed, the pen cap 62 is used to seal the first end of the pen barrel 61 to prevent the atomizing chip 4 from being contaminated. When the atomizing device 100 needs to be used, the pen cap 62 can be removed.

[0110] Specifically, the connection method between the pen cap 62 and the pen barrel 61 includes but is not limited to a snap connection, a magnetic connection or a screw connection. In a specific method, Fig.11 and Fig.12As shown, the pen cap 62 is provided with two buckle grooves 622, and the two buckle grooves 622 are symmetrically distributed. The outer wall of the first end of the pen barrel 61 is provided with two buckle protrusions 613, and the buckle protrusions 613 are arranged one-to-one with the buckle grooves 622. The pen cap 62 is sleeved on the outer periphery of the first end of the pen barrel 61, and is buckled one-to-one with the buckle grooves 622 through the buckle protrusions 613 to achieve a detachable connection between the two. Furthermore, in order to reduce the difficulty of buckling the buckling protrusion 613 with the buckling groove 622, the inner wall of the pen cap 62 is provided with two sliding grooves 623, and the sliding grooves 623 and the buckling grooves 622 are arranged one by one. The matching sliding grooves 623 and the buckling grooves 622 are arranged in sequence along the circumference of the pen cap 62 and are connected to each other. When assembling the pen cap 62 and the pen barrel 61, the buckling protrusion 613 is first inserted into the corresponding sliding groove 623, and then the pen cap 62 or the pen barrel 61 is rotated to make the buckling protrusion 613 and the buckling groove 622 buckle with each other. In this way, the pen cap 62 and the pen barrel 61 can be easily buckled. Of course, the number of the buckling protrusion 613, the buckling groove 622 and the sliding groove 623 is not limited to two, and can also be three, four or even more, as long as the three are arranged one by one.

[0111] Furthermore, if Figure 1 , Figure 6 and Fig.13 As shown, the atomization device 100 also includes a pen cap 63, which is connected to the second end of the pen barrel 61 to seal the second end of the pen barrel 61. The pen cap 63, the pen barrel 61 and the pen cover 62 together constitute the outer contour structure of the atomization device 100.

[0112] Specifically, the connection method between the pen cap 63 and the pen barrel 61 includes but is not limited to a screw connection, a snap connection or a magnetic connection. In a specific embodiment, Fig.10 and Fig.11 As shown, the inner wall of the pen cap 63 is provided with an internal thread 633, and the outer wall of the second end of the pen barrel 61 is provided with an external thread 614. The pen cap 63 and the pen barrel 61 are connected by screwing the internal thread 633 and the external thread 614, and the sealing performance is good.

[0113] In one embodiment, if Figure 6 , Fig.11 and Fig.13As shown, the pen barrel 61 is also provided with a mounting hole 616, and the atomizing device 100 also includes a visual window 9, which is transparent plastic or transparent glass. The visual window 9 is installed in the mounting hole 616, and the visual window 9 is opposite to the container 11, so as to view the remaining amount of the mixed material in the container 11. When the mixed material in the container 11 is used up, the pen cap 63 can be removed first, and the container 11 can be taken out by pulling the piston rod 21, the pen barrel 61 can be inverted, the sealing plug 12 can be taken out, and then the piston rod 21 and the container 11 can be separated, and then the container assembly 1 can be replaced, so as to realize the reuse of the atomizing device 100, save the use cost, and simplify the operation.

[0114] In one embodiment, if Figure 1 and Figure 6 As shown, the atomizing device 100 further includes a retainer 7, which is in a cylindrical shape and is used to retain the container 11 to prevent the container 11 from rotating, and the retainer 7 is installed in the pen barrel 61. Compared with the solution of directly assembling the container 11 with the pen barrel 61, this solution can reduce the processing requirements for the pen barrel 61. Specifically, the outer wall of the retainer 7 is interference-fitted with the inner wall of the pen barrel 61, and the inner wall of the retainer 7 is interference-fitted with the outer wall of the container 11, so as to fix the container 11.

[0115] Furthermore, if Figure 1 As shown, the size of the retainer 7 in the first direction a is smaller than the size of the container 11 in the first direction a, which is beneficial to the lightweight design of the atomizer 100. Furthermore, when the second end 112 of the container 11 is placed upward, the retainer 7 is located at the lower part of the pen barrel 61, which is beneficial to the stability of the center of gravity of the atomizer 100.

[0116] In one embodiment, if Figure 1 and Figure 6 As shown, the atomization device 100 also includes a trigger assembly 8, which includes an operating mechanism 81 and a pawl 82. The operating mechanism 81 is movably mounted on the pen barrel 61, and the pawl 82 is rotatably connected to the operating mechanism 81. The piston rod 21 is provided with a ratchet structure 211, and the ratchet structure 211 has a plurality of teeth arranged in sequence along the axial direction of the piston rod 21. The pawl 82 is used to engage with the ratchet structure 211 provided on the piston rod 21.

[0117] like Figure 1 , Figure 4 and Figure 5As shown, when the operating mechanism 81 moves along the first direction a under external force, the pawl 82 pushes the ratchet structure 211 to move the piston rod 21 along the first direction a, and the piston rod 21 pushes the first piston 22 and the second piston 23 to move to trigger atomization, that is, the user can trigger atomization through the operating mechanism 81, and the operation is convenient. When the operating mechanism 81 moves along the second direction b, the piston rod 21 does not move along with it, and the first direction a is opposite to the second direction b, and the first direction a and the second direction b are two opposite directions in the axial direction of the piston rod 21. In this way, the one-way path length of the operating mechanism 81 does not need to be set too large. When the operating mechanism 81 moves along the first direction a to the limit position of the one-way path, atomization is achieved. At this time, the operating mechanism 81 cannot continue to move along the first direction a. Then, the operating mechanism 81 can be driven to move along the second direction b to reset. At this time, the pawl 82 is engaged with another tooth portion of the ratchet structure 211, and the pawl 82 can continue to drive the piston rod 21 to move along the first direction a to achieve the next atomization. After the atomizing device 100 is repeatedly used for many times, the mixed material in the container 11 can be used up completely or as completely as possible.

[0118] Furthermore, if Figure 1 As shown, the operating mechanism 81 is provided with a limiting structure 8121, and the limiting structure 8121 is located at the end of the pawl 82 facing away from the container 11, so that when the pawl 82 moves along the first direction a, the pawl 82 can be stably engaged with the ratchet structure 211 under the abutment of the limiting structure 8121. The limiting structure 8121 is used to limit the rotation angle of the pawl 82, so that the pawl 82 can remain engaged with the ratchet structure 211 when the operating mechanism 81 moves along the first direction a under external force.

[0119] In one embodiment, if Figure 1 , Figure 6 and Fig.13 As shown, the operating mechanism 81 includes an operating element 811 and a switching element 812. The operating element 811 is at least partially located outside the pen barrel 61 for user operation. The switching element 812 is located inside the pen barrel 61 and connected to the operating element 811. The pawl 82 is rotatably connected to the switching element 812 via a pivot shaft 83. Preferably, the operating element 811 is a push button with a simple structure. The user can trigger atomization by pushing the operating element 811.

[0120] Specifically, Figure 1 and Fig.11As shown, the operating element 811 is provided with a connecting block 8111, the pen barrel 61 is provided with a long hole 615, the connecting block 8111 passes through the long hole 615 and extends into the pen barrel 61, and the connecting block 8111 is connected to the adapter element 812, so that the operating element 811 and the adapter element 812 can move synchronously. In addition, the hole wall of the long hole 615 can limit the moving direction of the connecting block 8111 to ensure that the operating element 811 can only move along the first direction a or the second direction b.

[0121] In one embodiment, if Fig. 9 and Fig.10 As shown, the pen cap 63 is provided with a limiting groove 631, and the piston rod 21 is provided with a limiting protrusion 212. The limiting groove 631 is engaged with the limiting protrusion 212 to limit the piston rod 21 from rotating relative to the pen cap 63. In this way, the piston rod 21 can only move along the first direction a.

[0122] Furthermore, if Figure 1 , Fig. 9 and Fig.10 As shown, the pen cap 63 is further provided with a receiving groove 632; when the atomizer 100 is in the initial state, part of the teeth of the ratchet structure 211 is located in the receiving groove 632, so that the piston rod 21 can be provided with as many teeth as possible to ensure that the operating element 811 can maintain a meshing state with the ratchet structure 211 after being reset, and at the same time, it will not occupy too much internal space of the pen barrel 61, thereby causing the pen barrel 61 to be too long. As the piston rod 21 moves along the first direction a, the teeth located in the receiving groove 632 gradually leave the receiving groove 632.

[0123] Further, when assembling the atomizing device 100, the following steps are included:

[0124] 1) After the piston rod 21 and the first piston 22 are assembled (for example, the two are mutually engaged through the engaging portion 213 and the engaging groove 221), they are pre-assembled with the pen cap 63 to form a first pre-assembled component;

[0125] 2) removing the bottle cap 13 of the container assembly 1, assembling the pen barrel 61 and the pen cap 62 (for example, by interlocking the interlocking protrusion 613 with the interlocking groove 622) and pre-assembling them with the container assembly 1 to form a second pre-assembled assembly;

[0126] 3) Assemble the first pre-assembled component with the second pre-assembled component, insert the piston rod 21 and the first piston 22 into the container 11, and rotate the pen cap 63 to screw the pen cap 63 with the pen barrel 61; it should be understood that in this step, in order to prevent the first raw material in the first chamber 31 from spilling out from the second end of the container 11, the second end of the container 11 needs to be placed upwards before assembly, and when the piston rod 21 and the first piston 22 are inserted into the container 11, the insertion of the first piston 22 first causes the first raw material to move from the first chamber 31 to the second chamber 32. In this process, the ratchet structure 211 is located above the pawl 82. When the first pre-assembled component and the second pre-assembled component are assembled, the pawl 82 is engaged with the first tooth portion below the ratchet structure 211;

[0127] 4) Assemble the pen cap 63 to the pen barrel 61 to complete the assembly of the atomizing device 100 .

[0128] It should be understood that the above embodiments are exemplary and are not intended to include all possible implementations included in the claims. Various modifications and changes may be made on the basis of the above embodiments without departing from the scope of the present disclosure. Similarly, the various technical features of the above embodiments may be arbitrarily combined to form other embodiments of the present invention that may not be explicitly described. Therefore, the above embodiments only express several implementations of the present invention and do not limit the scope of protection of the patent of the present invention.

Claims

1. An atomizing device, characterized in that: The atomizing device comprises: A container assembly, comprising a container and a sealing plug, wherein the container has an open first end and a second end, and the sealing plug is used to seal the first end; A piston assembly, comprising a piston rod, a first piston and a second piston, wherein the first piston and the second piston are sequentially arranged in the container along a first direction, and one end of the piston rod is located in the container and is linked to the first piston; Wherein, in the cavity of the container, a first chamber is formed on the side of the second piston facing away from the sealing plug, and a second chamber is formed between the second piston and the sealing plug; the first chamber is used to contain a first raw material, and the second chamber is used to contain a second raw material; When the piston rod pushes the first piston to move relative to the second piston in a first direction, the first raw material enters the second chamber and mixes with the second raw material to form a mixed material, and, in this process, the sealing plug is separated from the first end under the pressure of the mixed material.

2. The atomizing device according to claim 1, characterized in that: When the piston rod is assembled in the container, the piston rod pushes the first piston to move relative to the second piston along a first direction, so that the first raw material enters the second chamber.

3. The atomizing device according to claim 1, characterized in that: When the first piston moves along the first direction to abut against the second piston, the first raw material completely enters the second chamber.

4. The atomizing device according to claim 1, characterized in that: The first raw material is in liquid form, and the second raw material is in freeze-dried powder or liquid form.

5. The atomizing device according to claim 4, characterized in that: The second raw material is a nanobody in the form of a freeze-dried powder.

6. The atomizing device according to claim 1, characterized in that: The sealing plug is a rubber plug.

7. The atomizing device according to any one of claims 1 to 6, characterized in that: The inner wall of the container is provided with a groove, and a communication channel is formed between the groove and the outer wall of the second piston, and the first chamber and the second chamber are communicated with each other through the communication channel; Under the pressure of the first piston or under the action of the air pressure in the first chamber, the first raw material enters the second chamber through the connecting flow channel.

8. The atomizing device according to any one of claims 1 to 6, characterized in that: The atomization device also includes an atomization chip, which is located outside the sealing plug; When the hydraulic pressure of the liquid flowing out of the first end reaches a preset value, the liquid is processed by the atomization chip to form atomized fine particles and then escapes.

9. The atomizing device according to claim 8, characterized in that: The sealing plug is arranged in the port of the first end and the two are interference fit.

10. The atomizing device according to claim 9, characterized in that: When the sealing plug is separated from the first end, the sealing plug abuts against the atomization chip under the pressure of the mixed material.

11. The atomizing device according to claim 10, characterized in that: The sealing plug comprises a sealing plug body and a plurality of protrusion structures, wherein the protrusion structures are arranged on a side of the sealing plug body facing the atomization chip; When the sealing plug is separated from the first end, the protruding structure is used to form a first gap between the sealing plug body and the atomization chip, and the mixed material in the second chamber flows to the atomization flow channel of the atomization chip through the first gap.

12. The atomizing device according to claim 11, characterized in that: The atomization device further comprises a pen barrel, which is provided with a first hollow column and a second hollow column sequentially connected along a first direction; the container assembly and the piston assembly are both arranged in the pen barrel, and the atomization chip is installed in the second hollow column; When the sealing plug is detached from the first end, the sealing plug body is located in the first hollow column, a second gap is formed between the circumferential surface wall of the sealing plug body and the inner wall of the first hollow column, and the second chamber, the second gap, the first gap and the atomization channel are connected in sequence.

13. The atomizing device according to claim 12, characterized in that: The lateral space dimension of the first hollow column is greater than the lateral space dimension of the second hollow column; when the sealing plug is detached from the first end, the protruding structure abuts against the end surface of the second hollow column to reduce or completely avoid the covering of the atomization flow channel by the protruding structure.

14. The atomizing device according to claim 12, characterized in that: The sealing plug body comprises a first column and a second column connected in sequence along a first direction; The first column is in a truncated cone shape and gradually expands along the first direction; The second column is cylindrical, and its outer diameter is greater than or equal to the maximum outer diameter of the first column; when the sealing plug is assembled in the port of the first end, the outer wall of the second column is interference fit with the inner wall of the first end.

15. The atomizing device according to claim 14, characterized in that: The protruding structure partially protrudes outward from the circumferential surface wall of the second column; When the sealing plug is assembled in the port of the first end, the protruding structure is squeezed by the inner wall of the first end and deformed.

16. The atomizing device according to claim 12, characterized in that: The atomizing device further comprises a pen cover, wherein the pen cover is connected to the first end of the pen barrel; The pen cap is provided with a sealing column, and the sealing column is inserted into the second hollow column and the two are interference fit to seal the first end of the pen barrel.

17. The atomizing device according to claim 16, characterized in that The atomizing device also includes a pen cap, which is connected to the second end of the pen barrel and is used to seal the second end of the pen barrel.

18. The atomizing device according to claim 12, characterized in that: The atomizing device also includes a retaining member, which is used to retain the container and is installed in the pen barrel.

19. The atomizing device according to any one of claims 1 to 6, characterized in that: The atomizing device further comprises a pen barrel and a trigger assembly, wherein the container assembly and the piston assembly are both arranged in the pen barrel; the trigger assembly comprises: An operating mechanism, which is movably mounted on the pen barrel; A ratchet pawl, which is rotatably connected to the operating mechanism, and the ratchet pawl is used to engage with a ratchet structure provided on the piston rod; Wherein, when the operating mechanism moves in a first direction under an external force, the pawl pushes the ratchet structure to move the piston rod in the first direction, and the piston rod pushes the first piston and the second piston to move to trigger atomization; When the operating mechanism moves along the second direction, the piston rod does not move along with it, and the first direction is opposite to the second direction.

20. The atomizing device according to claim 19, characterized in that The operating mechanism is provided with a limiting structure, and the limiting structure is used to limit the rotation angle of the pawl, so that the pawl can remain engaged with the ratchet structure during the movement of the operating mechanism along the first direction.

21. The atomizing device according to claim 19, characterized in that The operating mechanism comprises: An operating element, which is at least partially located outside the pen barrel; A transfer element is located inside the pen barrel and connected to the operating element, and the pawl is rotatably connected to the transfer element.

22. The atomizing device according to claim 19, characterized in that The atomizing device further comprises a pen cap connected to the second end of the pen barrel to seal the second end of the pen barrel; The pen cap is provided with a limiting groove, and the piston rod is provided with a limiting protrusion; the limiting groove is engaged with the limiting protrusion to limit the piston rod from rotating relative to the pen cap.

23. The atomizing device according to claim 22, characterized in that The pen cap is also provided with a receiving groove; when the atomization device is in an initial state, the ratchet structure is partially located in the receiving groove.

24. The atomizing device according to claim 23, characterized in that The atomizing device further comprises a pen cover, wherein the pen cover is connected to the first end of the pen barrel; When assembling the atomizer device, the piston rod is assembled with the first piston and then pre-assembled with the pen cap to form a first pre-assembled component; the pen barrel and the pen cap are assembled and then pre-assembled with a container component to form a second pre-assembled component; then, the first pre-assembled component is assembled with the second pre-assembled component, and when the two are assembled, the pawl is engaged with the ratchet structure.

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