Packaging member for photosensitive pharmaceutical substance and packaging product comprising packaging member

By using packaging components made of hard sheet material with dark color coating, the problem of photosensitive drugs degradation due to light exposure during storage is solved, achieving a more efficient light shielding effect and a more convenient processing process.

CN119731093APending Publication Date: 2025-03-28F HOFFMANN LA ROCHE & CO AG
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Patent Information

Application Number
CN202380059839.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2022-09-07
Filing Date
2023-09-06
Publication Date
2025-03-28

AI Technical Summary

Technical Problem

The prior art lacks effective light protection when storing photosensitized drugs, resulting in degradation of drug ingredients and formation of toxic by-products, and is inconvenient to deal with, error-prone and high cost.

Method used

A packaging member made of a substantially hard sheet material, including the front wall, the rear wall and at least four side walls, the inner packaging surface is coated with a dark color to provide at least 50% light absorption, ensuring that the drug is not exposed to light when opened.

Benefits of technology

Effectively prevent photosensitive drugs from degrading due to light exposure, improve drug retention and safety, while improving packaging processing efficiency, reducing costs and reducing the risk of errors.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to a packaging member (1) for a light-sensitive pharmaceutical substance, said packaging member being made of a substantially hard sheet-like material defining an outer packaging surface (20) and an inner packaging surface (30). The packaging member (10) comprises a front wall member (1), a rear wall member (2) and at least four side wall members (3, 4, 5, 6). The inner packaging surface (30) of at least one of the front wall member (1), the rear wall member (1) and / or the at least four side wall members (3, 4, 5, 6) comprises a color adapted to provide at least about 50% light absorption.
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Description

Technical Field

[0001] The invention relates to a packaging element for photosensitive pharmaceutical substances according to the preamble of claim 1 . Background Art

[0002] It is well known that certain medical products (such as, for example, vitamins, antihistamines, some anticancer drugs, anti-infective drugs, cytostatics, cardiovascular agents, gastrointestinal therapeutic agents, psychotropic drugs, analgesics, etc.) are particularly sensitive to light and / or UV radiation. If such medicaments that require protection from light are not stored in a correct manner, degradation of the active ingredients and / or the formation of toxic by-products may occur, which may be detrimental to the health of the patient. It has been observed that ambient light that enters an opened standard pharmaceutical package containing the corresponding drug substance (e.g., tablets or pills or a comparable administrable dosage form) for a certain amount of time can have such negative effects.

[0003] Therefore, various packaging solutions have been proposed in order to create relief.

[0004] In order to facilitate quick access at the time of application, in practice, medical staff in large hospitals often remove the outer packaging of large doses of light-sensitive drug substances and store the light-sensitive drug substances in a dark box, and open the box for use when needed. Moreover, for example, medicine bottles or containers are stored in an open box with the outer packaging removed, and then covered with light-shielding fabric. When the bottle is taken out, the light-shielding fabric is removed. The disadvantages of such methods are that, firstly, it is inconvenient to take out the corresponding object, and secondly, when opening the packaging or uncovering the cover, many other drug substances / bottles are exposed to light.

[0005] In this context, CN 215664578 U describes an access box for light-shielding photosensitive drug substances, the access box comprising a box body and a plurality of slide slots arranged in the box body; the front end of the slide slot is arranged, and the front end of the slide slot is lower than the rear end of the slide slot; the front end and the rear end of the slide slot have a front recess and a rear recess respectively. The front recess is provided with a stopper for preventing the medicine bottle from automatically sliding out; the front recess and the rear recess are provided with a shading device, which includes a layered door or a layered soft curtain arranged between two upper eaves and a lower eaves adjacent to each other.

[0006] In EP 3 000 750 A1, a light-shielding sheet having a function of shielding light of a specific wavelength and capable of preventing light-shielding substances from being transferred into the contents and seeping out of the container, and a container produced using the light-shielding sheet are provided. The light-shielding sheet of the present invention has a multilayer structure of three or more layers, which includes at least one light-shielding layer that shields a specific wavelength and / or an eluate-blocking layer that blocks substances eluted from the light-shielding layer. When a container is manufactured from the light-shielding sheet, an eluate-blocking layer A is provided at least between the light-shielding layer and the innermost layer or on the innermost layer, and an eluate-blocking layer B is provided between the light-shielding layer and the outermost layer or on the outermost layer. The light-shielding layer may further serve as an eluate-blocking layer.

[0007] The aforementioned solutions have generally been shown to provide reasonable light shielding properties; however, they are associated with awkward handling, considerable expense and / or carry a certain risk of confusion.

[0008] Therefore, there is a need for a packaging solution that can provide comparable or even enhanced protection functions and which is at the same time more efficient, less error-prone and less costly to handle. Summary of the invention

[0009] According to the invention, this need is solved by a packaging element as defined by the features of independent claim 1. Preferred embodiments are subject matter of the dependent claims.

[0010] In one aspect, the present invention relates to a packaging member for a photosensitive drug substance, the packaging member being made of a substantially hard sheet material defining an outer packaging surface and an inner packaging surface. The packaging member comprises a front wall member, a rear wall member and at least four side wall members. The inner packaging surface of at least one of the front wall member, the rear wall member and / or the at least four side wall members comprises a color adapted to provide at least about 50% light absorption.

[0011] As used herein, the term "substantially hard sheet material" refers to a material that deforms only when subjected to an external force and includes a surface that is several times larger than its thickness. Thus, exemplary materials include in particular cartons, but also include, for example, plastic materials or plant-based materials having similar properties.

[0012] "Light absorption" as defined herein refers to the amount of light absorbed at normal incidence (measured using a standard spectrophotometer); ie specifically visible light as well as UV light. However, this does not exclude that light absorption may be even higher at other angles of incidence.

[0013] As defined herein, "color" includes particularly dark colors, especially black, but also includes, for example, dark gray, purple, dark blue, dark brown, dark green or dark red. In a preferred manner, the color is provided on the inner packaging or carton surface in the form of ink printing. Alternatively or additionally, a dark coating can be applied to the inner packaging or carton surface.

[0014] Thus, the packaging component of the present invention can provide very effective light shielding, wherein a light-sensitive drug substance can specifically be retained in its original secondary packaging or protective packaging (e.g. a tablet blister can be retained in its carton box), which secondary packaging or protective packaging can be opened by medical personnel or the patients themselves to remove the required dose without any associated light exposure (in particular due to light reflection from the inner wall of the packaging) which could lead to degradation of the components of the drug substance.

[0015] In other words, the packaging member of the present invention generally combines the advantages of a relatively short light exposure through a relatively small opening of a medication box with significantly reduced light reflection at its inner surface.

[0016] It should be pointed out that a significant protective effect can already be achieved if (only) the inner surface of the broad side of the usually rectangular packaging member directly facing the medicinal substance within the packaging member comprises a corresponding color.

[0017] Preferably, the inner packaging surface of at least two of the front wall member, the rear wall member and / or the at least four side wall members comprises a color adapted to provide at least about 50% light absorption. In this way, light shielding efficiency can be further improved. In a particularly preferred embodiment, the inner packaging surface of two wide side wall members of the package of a rectangular shape, for example, comprises corresponding colors.

[0018] Preferably, the inner packaging surface of at least three of the front wall member, the rear wall member and / or the at least four side wall members comprises the color that is adapted to provide at least about 50% light absorption. In this way, light shielding efficiency can still be further improved. In a particularly preferred embodiment, the inner packaging surface of two wide side wall members and a small side wall member of the packing of for example rectangular shape comprises corresponding color.

[0019] Preferably, the inner packaging surface of at least four of the front wall member, the rear wall member and / or the at least four side wall members comprises a color adapted to provide at least about 50% light absorption. Equally, light shielding efficiency can be further improved. In a particularly preferred embodiment, the inner packaging surface of all four side wall members of the rectangular-shaped package comprises a corresponding color, so as to effectively avoid / reduce reflection.

[0020] Preferably, the inner packaging surface of at least five of the front wall member, the rear wall member and the at least four side walls comprises a color adapted to provide at least about 50% light absorption. Again, the light shielding efficiency can be further improved. In a particularly preferred embodiment, the inner packaging surface of the front wall member and the four side wall members of the package of a rectangular shape, for example, comprises a corresponding color, so as to effectively avoid / reduce reflection (that is, particularly when the package has been opened once).

[0021] Preferably, the inner packaging surface of the front wall member, rear wall member and four side wall members of the rectangular shaped package for example comprises the color that is adapted to provide at least about 50% light absorption.In this way, owing to relating to complete inner packaging surface, therefore can realize best light shielding efficiency.

[0022] Preferably, the color is adapted to provide at least about 75%, more preferably at least about 90%, still more preferably at least about 95% and even more preferably at least about 99% light absorption. Thus, for each or all of the inner packaging surfaces, i.e., according to the specific color and / or surface characteristics applied, the fraction of reflected light can still be further reduced.

[0023] Preferably, the front wall member comprises a front closure flap and / or the rear wall member comprises a rear closure flap. The closure flap is used for a reliable closing / opening function of the packaging member. They usually comprise the same color as the front wall member or the rear wall member on the inner packaging surface. However, it is also conceivable that the closure flap comprises a color different from the color of the front wall member or the rear wall member.

[0024] Preferably, at least two of the side wall members include a front side wing piece and / or a rear side wing piece. The side wing pieces serve as additional protection measures and support the safe closure of the front closure wing piece and the rear closure wing piece. They usually include the same color as the corresponding side wall member on the inner packaging surface. However, it is also conceivable that the side wing piece includes a color different from the color of the side wall member.

[0025] Preferably, at least one of the (outer) side wall members of the packaging member comprises an adhesive flap. The adhesive flap is adapted to receive a glue or adhesive application thereon, by which the respective outer side wall is fixedly attached to the other outer side wall of the packaging member during assembly.

[0026] Preferably, the (outer) side wall member opposite to the (outer) side wall member with the adhesive tab comprises an uncolored area on the inner packaging surface, which preferably corresponds to the adhesive tab. In this way, the dark color can be retained and the best adhesive strength can be ensured, because no wear will occur at the bonding or gluing site, which has been found to have an adverse effect in this regard. It should be noted in this regard that the term "uncolored" will be understood as making the corresponding area not printed and / or coated with light absorbing dark colors. Therefore, the uncolored area usually has the same color as the outer carton or outer packaging surface, which color is usually but not necessarily white.

[0027] Preferably, the rest of the inner packaging surface of the side wall member, except for the uncolored area, comprises a dark color adapted to provide light absorption. It was found that if four side wall members comprise a dark color, while the other flaps and the front wall member or the rear wall member remain uncolored at the inner packaging surface, very good light protection and considerable color saving can be achieved simultaneously. Due to the fact that the side flaps, the closing flaps and the front wall member and the rear wall member provide overlap in the assembled state, it is sufficient for most applications when (only) the side wall member is provided with a dark color.

[0028] Preferably, the fold lines formed between the individual side wall elements and between the side wall element with the adhesive flap and the adhesive flap itself remain uncolored. Further preferably, the fold lines between the (outer) side wall element with the adhesive flap and its side flap, between the adjacent side wall element and its front wall element, between the further adjacent side wall element and its side flap and between the (further outer) side wall element and its rear wall element also remain uncolored. In this way, additional ink can be saved while still ensuring very good light protection. In addition, smears on the folding machine can be avoided in an effective manner.

[0029] Preferably, the adhesive flap comprises an adhesive section and a shielding section, wherein the shielding section preferably has an attachment portion. In this way, a shielding and holding configuration can be formed within the assembled (respectively folded and glued) packaging component, which shielding and holding configuration holds, for example, a vial in place and also protects the latter from shocks and vibrations.

[0030] Preferably, the side wall member opposite to the side wall member with the adhesive tab comprises an uncolored area on the inner packaging surface, which preferably corresponds to the adhesive section of the adhesive tab. Also in this case, the dark color can be retained and the best adhesive strength can be ensured, because no wear will occur at the adhesive or gluing site, which has been found to have a negative effect in this regard.

[0031] Further preferably, the side wall member with the adhesive flap comprises an uncolored area on the inner packaging side, which preferably corresponds to the attachment portion of the shielding section of the adhesive flap. The attachment portion comprises a dark color at its inner packaging surface so that it can, on the one hand, cover the uncolored area to ensure light protection and, on the other hand, provide optimal bonding.

[0032] Preferably, one of the side wall elements (in particular the side wall element facing the side wall element with the adhesive tab in the assembled state) comprises a rear side flap with a folded section, wherein the folded section preferably has an attachment portion. Thereby, a supporting and retaining formation can be formed in the assembled (folded and glued, respectively) packaging element, which supports, for example, a vial in place and also protects the latter from shocks and vibrations.

[0033] Preferably, the side wall member with the rear wing sheet includes an uncolored area on the inner packaging surface, which preferably corresponds to the attachment portion of the rear wing sheet. The attachment portion covers the uncolored area to ensure optimal bonding. Here, the attachment portion does not necessarily need to be provided with a dark color.

[0034] Preferably, at least one of the side wall members comprises an access opening.The access opening provides for convenient handling and is preferably provided in the unfolded packaging member in the form of a perforated section which is removed by the user when opening the packaging member for the first time.

[0035] Preferably, the color is applied to the inner packaging surface in the form of dark ink printing. The most preferred color for dark ink printing is black, but dark grey, purple, dark blue, dark brown, dark green and dark red can also be used advantageously. Dark ink printing represents a particularly cost-effective method. Preferably, dark ink printing is arranged in one or two or more layers. Further preferably, the dark ink printing layer can be provided with an additional dark lacquer layer. The most preferred color for the dark lacquer layer is black as well, but dark grey, purple, dark blue, dark brown, dark green and dark red can also be used advantageously. It is also generally conceivable that the printed surface is subjected to chemical and / or mechanical pretreatment, so that light absorption is even more effective, particularly with respect to angles of incidence other than 90 ° (such as, for example, 45 °).

[0036] Preferably, the color is applied to the inner packaging surface in the form of a dark coating (or a surface printed with a similarly dark ink). Such coatings may, for example, include functional surfaces such as carbon-based nanotubes or etched nickel-phosphorus alloys.

[0037] Preferably, the substantially hard sheet-like material comprises a uniform thickness. In this way, an unimpeded printing and / or coating process can be ensured.

[0038] Preferably, the packaging member is in the form of a secondary / secondary packaging member defining a containment space for a photosensitive drug substance contained in a primary / primary / primary package. A typical application of the package of the present invention is pills provided in several blister layers (as primary packages), wherein the blister layers are enclosed in a medicament containment space defined by the inner surface of the package wall member.

[0039] Another aspect of the invention relates to a (secondary) packaged product comprising a packaging member as described above and a light-sensitive pharmaceutical substance in a primary package, preferably the light-sensitive pharmaceutical substance in the primary package being contained within the packaging member. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] The packaging member according to the present invention is described in more detail below by means of exemplary embodiments and with reference to the accompanying drawings, in which:

[0041] Figure 1 : A top view on the outer surface of a packaging member of the prior art in an unfolded state;

[0042] Figure 2 : A top view on the inner surface of a packaging member of the prior art in an unfolded state;

[0043] Figure 3 : A perspective view of a packaging component of the prior art in an assembled state;

[0044] Figure 4 : A top view on the outer surface of the packaging member of the present invention in an unfolded state;

[0045] Figure 5 : A top view on the inner surface of the packaging member of the present invention in an unfolded state;

[0046] Figure 6 : A perspective view of a packaging member of the present invention in an assembled state;

[0047] Figure 7 : A top view of the inner surface of a preferred embodiment of a packaging member of the present invention in an unfolded state;

[0048] Figure 7 : A top view of the inner surface of another preferred embodiment of the packaging member of the present invention in an unfolded state; and

[0049] Figure 8 : A top view of the inner surface of yet another preferred embodiment of a packaging member of the present invention in an unfolded state. DETAILED DESCRIPTION

[0050] In the following description, some terms are used for convenience and are not intended to limit the present invention. The terms "right", "left", "up", "down", "below" and "above" refer to the directions in the figure. The terms include the terms and their derivatives and terms with similar meanings that are explicitly mentioned. In addition, spatial relative terms such as "below ... ", "below", "below", "above", "above", "near side", "distal side" etc. can be used to describe the relationship between an element or feature and another element or feature as shown in the figure. These spatial relative terms are intended to cover different positions and orientations of the device in use or operation in addition to the positions and orientations shown in the figure. For example, if the device in the accompanying drawings is turned over, the elements described as "below" or "below ... below" of other elements or features will be "above" or "above ... above" of other elements or features. Therefore, the exemplary term "below" can cover the position and orientation of the top and bottom. The device can be oriented in other ways (rotated 90 degrees or in other orientations), and the spatial relative descriptors used in this article are interpreted accordingly. Similarly, the description of the movement along and around various axes includes various specific device positions and orientations.

[0051] To avoid repetition in the drawings and the description of the various aspects and illustrative embodiments, it should be understood that many features are common to many aspects and embodiments. The omission of an aspect in the description or drawings does not imply that the aspect is missing in the embodiment containing the aspect. On the contrary, the aspect may be omitted for clarity and to avoid lengthy descriptions. In this context, the following description applies to the rest of this specification: if a reference numeral is included in the drawings that is not explained in the directly relevant part of the specification for the purpose of illustrating the drawings, reference may be made to the previous or subsequent parts of the specification. In addition, for reasons of clarity, if a reference numeral is not provided in the drawings for all features of a certain component, reference may be made to other drawings showing the same component. Similar reference numerals in two or more drawings represent the same or similar elements.

[0052] Figure 1 A top view of an outer packaging surface 20' or outer carton of a prior art packaging member 10' is shown in an unfolded state. In such prior art packaging members, the outer carton 20' typically has a white color with the brand of the corresponding drug or medicament printed thereon.

[0053] Figure 2 A top view of an inner packaging surface 30' or inner carton of a prior art packaging member 10' is shown in an unfolded state. In such prior art packaging members, the inner carton 30' comprises an inner surface that is not printed, ie, has a bright color that reflects most of the incident light.

[0054] exist Figure 3In the figure, the prior art packaging member 10' is depicted in its assembled (box-like) state, wherein the carton defines a receiving space 62' of the box 10', wherein the inner packaging surface remains unprinted. Therefore, in the open state of the packaging member 10', incident light will be reflected by the inner sidewalls and thus directed onto the pills in the blisters, for example, within the receiving space 62'.

[0055] Figure 4 A top view of an outer packaging surface 20 or outer carton of the packaging member 10 of the present invention is shown in an unfolded state. Moreover, the packaging member of the present invention typically includes a white outer carton 20 having the brand of the corresponding drug or medicament printed thereon.

[0056] The packaging member 10 includes a front wall member 1, a rear wall member 2, and side wall members 3, 4, 5, and 6, wherein the side wall members 3 and 5 represent small side walls, and the side wall members 4 and 6 represent wide side walls of the packaging member 10. The outer side wall member 3 includes a front side wing piece 31 and a rear side wing piece 32. Figure 6 In the assembled state shown, the front and rear side flaps interact with the front and rear side flaps 51 and 52 of the inner side wall member 5. The outer side wall member 3 also comprises an adhesive flap 33 at its free longitudinal side, by means of which the outer side wall member 3 is attached (from the inside) to the free longitudinal side of the wide side wall member 6. The inner wide side wall member 4 comprises a top wall member 1 with a top closing flap 11 at its top end. The outer wide side wall member 6 in turn comprises a rear wall member 2 with a rear closing flap 22 at its rear end. Folding lines f (shown only as an example) are provided between the outer small side wall member 3 and the adhesive flap 33 and the side flaps 31, 32, between the inner wide side wall member 4 and the top wall member 1, between the top wall member 1 and the top closing flap 11, between the inner small side wall member 5 and the side flaps 51 and 52, between the outer wide side wall member 6 and the rear wall member 2, and between the rear wall member 2 and the rear closing flap 22. The fold line f may be provided in the form of a weakening in the carton material.

[0057] Figure 5 A top view of the inner packaging surface 30 or inner carton of the packaging member 10 of the present invention is shown in an unfolded state. Figure 5 and Figure 4 Symmetrically identical (i.e. similar to Figure 1 and Figure 2 ) and the corresponding elements include Figure 4 In combination with the above Figures 1 to 3The solution of the prior art described, the packaging member 10 according to the present invention comprises a dark color (and / or dark coating) on ​​its entire inner surface 30, which is adapted to absorb up to almost all incident light. However, it is also conceivable that only some of the wall members and / or flaps comprise a dark color, which ultimately depends on the drug or medicine to be received by the packaging member 10. In addition, it is also conceivable that some or all of the wall members and / or flaps comprise individually different colors.

[0058] exist Figure 6 In the figure, the packaging member 10 of the present invention is depicted in its assembled (box-like) state, wherein the carton defines a (dark) receiving space 62 of the box 10, which comprises a uniform dark color for ensuring the desired light shielding. Thus, in the open state of the packaging member 10, light will be almost completely absorbed by the inner side walls and thus will not be directed onto the pills in the blisters, for example, within the dark receiving space 62. In other embodiments, the exemplary access opening 61 may also be omitted.

[0059] Figure 7 A top view of the inner packaging surface 30 or inner carton of a preferred embodiment of the packaging member 10 of the present invention is shown in an unfolded state. Figure 7 and Figure 5 are substantially the same, and corresponding elements include Figure 5 Same reference numerals as in Figure 5 Compared with the packaging components shown and described, Figure 7 The packaging member 10 includes an uncolored area 63 at the outer edge of the side wall member 6, which corresponds to the bonding flap 33 of the side wall member 3. The outer (uncolored) surface of the bonding flap 3 is glued together with the uncolored area 63 of the side wall member 6. In this way, dark color can be saved and the adhesive bond is stronger than when the colored and uncolored surfaces are glued together.

[0060] exist Figure 8 In another preferred embodiment shown, the front wall element 1 with the closing flap 11, the rear wall element 2 with the closing flap 22, the side flaps 51, 52 and the side flaps 31, 32 also remain uncolored, i.e. together with the uncolored area 63 of the side wall element 6. In this way, more dark color can be saved without significantly hampering the light absorption effect caused by the overlap formed by the aforementioned wall elements and flaps.

[0061] Fig. 9The top view of the inner packaging surface 30 or inner carton of another preferred embodiment of the packaging member 10 of the present invention in an unfolded state is shown. Here, the front wall member 1 with closed flap 11, the rear wall member 2 with closed flap 22, the side flaps 51, 520 and the side flaps 31, 32 remain uncolored. The side wall member 6 includes an uncolored area 64, the side wall member 5 includes an uncolored area 66, and the side wall member 3 includes an uncolored area 65. Moreover, the (vertical) folding line f formed between the side wall member 3 with adhesive flaps 33, 330 and the adhesive flaps 33, 330 itself remains uncolored. In addition, the (horizontal) folding line f between the side wall member 3 and its side flaps 31, 32, between the side wall member 4 and its front wall member 1, between the side wall member 5 and its side flaps 52, 520 and between the side wall member 6 and its rear wall member 2 also remains uncolored.

[0062] The bonding tab 330 of the side wall member 3 of this embodiment is connected to, for example, Figure 7 and Figure 8 The adhesive flap 330 is extended compared to the adhesive flap 33 shown. Here, the adhesive flap 330 includes an adhesive section 331, a shielding section 332 and an attachment portion 333. The adhesive flap 330 is folded four times, namely, around the folding line f formed between the side wall member 3 and the adhesive section 331, around the additional folding line f' formed between the adhesive section 331 and the shielding section, around the additional folding line f' formed in the middle position of the shielding section 332, and around the additional folding line f' formed between the shielding section 332 and the attachment portion 333 at the outer end of the adhesive flap 330. The uncolored outer surface of the attachment portion 333 is glued together with the uncolored area 65 of the side wall member 3. Thus, a rectangular shield or holding structure for a vial in a package is produced, for example. The uncolored outer surface of the adhesive section 331 is glued together with the uncolored area 64 of the side wall member 6.

[0063] In a similar manner to the adhesive flap 330, the rear side flap 520 is folded four times, namely around the fold line f formed between the side wall member 5 and the folded section 521, around two additional fold lines f' formed in the middle position of the folded section 521, and around an additional fold line f' formed between the folded section 521 and the attachment portion 522 at the outer end of the rear side flap 520. The uncolored outer surface of the attachment portion 522 is glued together with the uncolored area 66 of the side wall member 5. Thereby, a base-like support or holding structure for, for example, a vial in a package is produced, which together with the shield or holding structure provides easy and effective protection for, for example, a vial contained in an assembled box.

[0064] This description and drawings illustrating aspects and embodiments of the invention should not be construed as limiting the claims defining the protected invention. In other words, although the invention has been illustrated and described in detail in the drawings and the foregoing description, such illustration and description are considered to be illustrative or exemplary rather than restrictive. Various mechanical, compositional, structural, electrical and operational changes may be made without departing from the spirit and scope of the specification and claims. In some cases, well-known circuits, structures and techniques are not shown in detail so as not to obscure the invention. Therefore, it should be understood that changes and modifications may be made by those of ordinary skill in the art within the scope and spirit of the appended claims.

[0065] The present disclosure also covers all other features shown in the figures. Although they may not be described in the preceding or following description, they are separate. In addition, single alternatives of the embodiments described in the drawings and description and single alternatives of their features may be excluded from the subject matter of the present invention or from the disclosed subject matter. The present disclosure includes subject matter consisting of features defined in the claims or exemplary embodiments as well as subject matter including said features.

[0066] Furthermore, in the claims, the term "comprises / includes" does not exclude other elements or steps, and the indefinite article "a / an" does not exclude a plurality. A single unit or step may perform the functions of several features listed in the claims. The mere fact that certain measures are listed in mutually different dependent claims does not indicate that the combination of these measures cannot be advantageous. The terms "substantially", "about", "approximately", etc., which are related to attributes or values, also accurately define the attributes or accurate values, respectively. In the context of a given value or range, the term "about" refers to a value or range within 20%, 10%, 5% or 2% of a given value or range, for example. Components described as coupled or connected may be directly coupled electrically or mechanically, or they may be indirectly coupled via one or more intermediate components. Any figure marks in the claims should not be interpreted as limiting the scope.

[0067] List of reference numerals:

[0068] 1 Front wall member

[0069] 2 Rear wall components

[0070] 3 Side wall member (narrow side)

[0071] 4 Side wall member (wide side)

[0072] 5 Side wall member (narrow side)

[0073] 6 Side wall member (wide side)

[0074] 10 Packaging components

[0075] 10' Packaging components (prior art)

[0076] 11 Closing flap (front)

[0077] 20 Outer packaging surface

[0078] 20' outer packaging surface (existing technology)

[0079] 22 Closing flap (rear)

[0080] 30 Inner packaging surface

[0081] 30' inner packaging surface (existing technology)

[0082] 31 Side wing (front)

[0083] 32 Side wing (rear)

[0084] 33 Bonding wing( Figure 4 , Figure 5 and Figure 7 )

[0085] 330 Bonding wing( Figure 8 )

[0086] 331 bonding section

[0087] 332 Shielded Section

[0088] 333 (External) Attachment

[0089] 51 Side wing (front)

[0090] 52 Side wing (rear) ( Figure 4 , Figure 5 and Figure 7 )

[0091] 520 Side Wings (Back) ( Figure 8 )

[0092] 521 Fold Section

[0093] 522 (External) Attachment

[0094] 61 Access opening

[0095] 62 Accommodation Space

[0096] 62' Accommodation Space (Existing Technology)

[0097] 63 Uncolored area ( Figure 7 and Figure 8 )

[0098] 64 Uncolored area ( Fig. 9 )

[0099] 65 Uncolored area ( Fig. 9 )

[0100] 66 Uncolored area ( Fig. 9 )

[0101] f Folding line (example)

[0102] f' fold line( Fig. 9 Additional fold lines in

Claims

1. A packaging member (10) for a photosensitive drug substance, the packaging member being made of a substantially rigid sheet material defining an outer packaging surface (20) and an inner packaging surface (30), wherein The packaging component (10) comprises a front wall component (1), a rear wall component (2) and at least four side wall components (3, 4, 5, 6), and is characterized in that: The inner packaging surface (30) of the front wall member (1), the rear wall member (1) and / or at least one of the at least four side wall members (3, 4, 5, 6) comprises a color suitable for providing at least about 50% light absorption.

2. The packaging member (10) according to claim 1, wherein: The inner packaging surface (30) of the front wall member (1), the rear wall member (1) and / or at least two of the at least four side wall members (3, 4, 5, 6) comprises a color suitable for providing at least about 50% light absorption.

3. The packaging member (10) according to claim 1, wherein: The inner packaging surface (30) of the front wall member (1), the rear wall member (1) and / or at least three of the at least four side wall members (3, 4, 5, 6) comprises a color suitable for providing at least about 50% light absorption.

4. The packaging member (10) according to claim 1, wherein: The inner packaging surface (30) of the front wall member (1), the rear wall member (1) and / or at least four of the at least four side wall members (3, 4, 5, 6) comprises a color suitable for providing at least about 50% light absorption.

5. The packaging member (10) according to claim 1, wherein: The inner packaging surface (30) of the front wall member (1), the rear wall member (1) and at least five of the at least four side wall members (3, 4, 5, 6) comprises a color suitable for providing at least about 50% light absorption.

6. The packaging member (10) according to claim 1, wherein: The inner packaging surfaces (30) of the front wall member (1), the rear wall member (1) and the four side wall members (3, 4, 5, 6) comprise a color suitable for providing at least about 50% light absorption.

7. The packaging element (10) according to any one of the preceding claims, wherein: The color is adapted to provide at least about 75%, preferably at least about 90%, more preferably at least about 95%, and still more preferably at least about 99% absorption of light.

8. The packaging element (10) according to any one of the preceding claims, wherein: The front wall element (1) comprises a front closure flap (11) and / or the rear wall element (2) comprises a rear closure flap (22).

9. The packaging element (10) according to any one of the preceding claims, wherein: At least two of the side wall members (3, 4, 5, 6) include a front side wing panel (31, 51) and / or a rear side wing panel (32, 52, 520).

10. The packaging element (10) according to any one of the preceding claims, wherein At least one of the side wall members (3, 4, 5, 6) comprises an adhesive tab (33, 330).

11. The packaging member (10) according to claim 10, wherein: The side wall member (6) opposite to the side wall member (3) having the adhesive flap (33, 330) comprises an uncolored area (63) on the inner packaging surface (30), the uncolored area preferably corresponding to the adhesive flap (33, 330).

12. The packaging member (10) according to claim 11, wherein: Apart from said uncolored areas (63), the remainder of the inner packaging surface (30) of the side wall member (3, 4, 5, 6) comprises said color suitable for providing light absorption.

13. The packaging member (10) according to any one of claims 10 to 12, wherein: The fold lines (f) formed between the individual side wall members (3, 4, 5, 6) and between the side wall member (3) with the adhesive flap (33, 330) and the adhesive flap itself remain uncolored.

14. The packaging member (10) according to any one of claims 10 to 13, wherein: The bonding tab (330) comprises a bonding section (331) and a shielding section (332), wherein the shielding section (332) preferably has an attachment portion (333).

15. The packaging member (10) according to claim 14, wherein: The side wall member (6) opposite to the side wall member (3) having the adhesive flap (330) includes an uncolored area (64) located on the inner packaging surface (30), and the uncolored area preferably corresponds to the adhesive section (331) of the adhesive flap (330).

16. The packaging member (10) according to any one of claims 14 to 15, wherein: The side wall member (3) having the adhesive flap (330) includes an uncolored area (65) located on the inner packaging side (30), and the uncolored area preferably corresponds to the attachment portion (333) of the shielding section (332) of the adhesive flap (330).

17. The packaging member (10) according to any one of claims 14 to 16, wherein: One of the side wall members, preferably the side wall member (5) facing the side wall member (3) having the bonding wing (330) in the assembled state, includes a rear side wing (520) having a folded section (521), wherein the folded section (521) preferably has an attachment portion (522).

18. The packaging member (10) according to claim 17, wherein: The side wall member (5) having the rear side flap (520) comprises an uncolored area (66) on the inner packaging surface (30), the uncolored area preferably corresponding to the attachment portion (522) of the rear side flap (520).

19. The packaging element (10) according to any one of the preceding claims, wherein At least one of the side wall members (3, 4, 5, 6) comprises an access opening (61).

20. The packaging element (10) according to any one of the preceding claims, wherein The color is applied to the inner packaging surface (30) in the form of a dark print.

21. The packaging element (10) according to any one of the preceding claims, wherein The color is applied to the inner packaging surface (30) in the form of a dark coating.

22. The packaging element (10) according to any one of the preceding claims, wherein The packaging member (1) is in the form of a secondary package defining a containment space (62) for a photosensitive pharmaceutical substance in a primary package.

23. A packaged product comprising a packaging member (1) according to any one of the preceding claims and a photosensitive pharmaceutical substance contained within the packaging member (1).

Citation Information

Patent Citations

  • Light-shielding sheet and container

    EP3000750A1