Method for extracting multiple components of traditional Chinese medicine compound based on supercritical fluid chromatography technology

By applying supercritical fluid chromatography technology and pre-precipitation steps of ethanol in traditional Chinese medicine compound preparations, the problem of low multi-component extraction and separation efficiency of traditional Chinese medicine compound preparations in the prior art was solved, and high-efficiency and low-consumed multi-component preparation was achieved, and the preparation efficiency and purity were improved.

CN119780263APending Publication Date: 2025-04-08TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
0 Cites 0 Cited by

Patent Information

Application Number
CN202411785545.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-06
Publication Date
2025-04-08

AI Technical Summary

Technical Problem

The prior art is difficult to effectively use supercritical fluid chromatography technology to efficiently extract and separate multi-components in traditional Chinese medicine compound preparations, which has problems such as expensive instruments and equipment, high solvent consumption and large post-treatment workload.

Method used

Supercritical fluid chromatography technology is used, CO2 is used as the mobile phase, combined with the pre-deposition step of ethanol, to achieve the simultaneous preparation of multi-components in the compound Xiaoyao San of Chinese medicine.

Benefits of technology

It realizes efficient extraction and separation of multi-components in the compound preparation of traditional Chinese medicine, reduces solvent consumption and post-treatment workload, improves preparation efficiency and purity, and saves manpower and material resources.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The invention provides a supercritical fluid chromatography technology-based traditional Chinese medicine compound multi-component extraction method, which comprises: (1) carrying out pretreatment on traditional Chinese medicine compound Xiaoyao powder to obtain a sample to be detected; (2) preparing standard solutions of apiose liquiritin, apiose isoliquiritin, paeoniflorin, albiflorin, saikoside A and saikoside D; and (3) carrying out supercritical fluid chromatographic analysis on the to-be-detected sample, and extracting. According to the extraction method of the traditional Chinese medicine compound multi-component based on the supercritical fluid chromatography technology, the simultaneous preparation of the multi-component (apiose liquiritin, apiose isoliquiritin, paeoniflorin, albiflorin, saikoside A and saikoside D) in the traditional Chinese medicine compound preparation Xiaoyao powder can be realized.
Need to check novelty before this filing date? Find Prior Art