Suction type dosing device

Abstract

The invention relates to the technical field of drug delivery devices, and discloses a suction type drug delivery device which comprises a capsule for storing dry powder and further comprises a partition plate fixedly arranged in the capsule and dividing the internal space of the capsule into an upper storage cavity and a lower storage cavity; a moving groove for allowing the capsule to pass through is transversely formed in the shell in a penetrating manner; the upper tool bit and the lower tool bit are fixedly mounted at the top and the bottom of the moving groove respectively, and when the capsule passes through the moving groove, the upper tool bit and the lower tool bit are used for cutting off the top end and the bottom end of the capsule respectively. A partition plate is arranged in the capsule, different types of medicines can be effectively separated, independence of the medicines during storage is ensured, mutual reaction is prevented, the two medicines can be released according to a preset proportion during inhalation, and personalized treatment requirements are met. When a patient inhales the medicine, two different types of medicine released from the capsule can be instantly mixed in the mixing tube, so that the medicine inhaled by the patient is uniform, and the treatment effect is remarkably improved.

Description

Technical Field

[0001] The present invention relates to the technical field of drug delivery devices, in particular to an inhalation drug delivery device. Background Art

[0002] In respiratory medicine, dry powder inhalation drug delivery devices have gradually become an important means of clinical application due to their convenience and efficiency. Traditional drug delivery methods (such as oral or injection) have problems such as slow drug absorption and poor patient compliance, while inhalation drug delivery can directly act on the respiratory tract and lungs, significantly improving the bioavailability of drugs.

[0003] However, existing dry powder inhalation drug delivery devices generally use a single drug storage design and cannot achieve instant mixing and precise delivery of different types of drugs (such as Chinese patent CN116764043B). In the treatment of asthma and chronic obstructive pulmonary disease, doctors often need to use bronchodilators (such as salbutamol) and steroids (such as budesonide) at the same time to relieve symptoms and control inflammation. However, existing devices often cannot effectively mix these two drugs before inhalation, causing patients to inhale them separately, increasing the complexity of use and the discomfort of patients. Summary of the invention

[0004] 1. Technical issues to be resolved In view of the shortcomings of the prior art, the present invention provides an inhalation drug delivery device, which has the advantage of being able to instantly mix two drugs during inhalation.

[0005] (II) Technical solution In order to achieve the above-mentioned purpose of being able to instantly mix two drugs during inhalation, the present invention provides the following technical solution: an inhalation drug delivery device, comprising a capsule for storing dry powder, and further comprising: A partition is fixedly disposed in the capsule to separate the internal space of the capsule into an upper storage chamber and a lower storage chamber; A housing having a movable groove extending therethrough for allowing the capsule to pass therethrough; The upper cutter head and the lower cutter head are fixedly mounted on the top and bottom of the moving groove respectively. When the capsule passes through the moving groove, the upper cutter head and the lower cutter head are used to cut off the top and bottom of the capsule respectively. The medicine inhaler is installed on the top of the shell, and the bottom end is connected with the moving groove through the suction groove and the upper through groove on the upper cutter head; The medicine receiving groove is provided in the shell, and the top end is connected with the moving groove through the lower through groove on the lower cutter head; One end of the branch pipe is connected to the medicine receiving trough, and the other end is connected to the medicine inhaler.

[0006] As a preferred technical solution of the present invention, it also includes a transverse plate, on which fixed sleeves adapted to the capsules are evenly mounted, and the capsules are inserted into and tightly bound in the fixed sleeves.

[0007] As a preferred technical solution of the present invention, it also includes two guide plates arranged opposite to each other and fixedly mounted on the side of the shell to guide the capsule to move and enter the moving groove.

[0008] As a preferred technical solution of the present invention, the movable groove has a side opening corresponding to the length of the capsule on one side of the upper and lower cutting heads, and the side opening allows the upper and lower cutting heads to be suspended in the air.

[0009] As a preferred technical solution of the present invention, the drug inhaler is composed of a drug outlet pipe, a mixing pipe and a suction nozzle connected in sequence from top to bottom, and the drug outlet pipe is fixedly installed on the top of the shell and communicated with the suction groove; The upper end of the branch pipe is communicated with the medicine outlet pipe.

[0010] As a preferred technical solution of the present invention, the mixing tube is a spherical tube with a plurality of baffles installed in an alternating manner inside.

[0011] As a preferred technical solution of the present invention, the mixing tube is a spiral tube or an S-shaped tube.

[0012] As a preferred technical solution of the present invention, a side air groove is provided between the side wall of the suction groove and the outside of the shell.

[0013] As a preferred technical solution of the present invention, a vertical groove is provided at the bottom of the medicine receiving groove, and a one-way air inlet valve is provided in the vertical groove.

[0014] As a preferred technical solution of the present invention, the one-way air intake valve includes a diaphragm, a column, a mounting plate and a fixing rod. A mounting plate is fixedly installed in the vertical groove by the fixing rod. The top of the mounting plate is connected to the diaphragm through the column, and the diaphragm covers the top of the vertical groove.

[0015] (III) Beneficial effects Compared with the prior art, the present invention provides an inhalation drug delivery device having the following beneficial effects: 1. The inhalation drug delivery device has a partition in the capsule, which can effectively separate different types of drugs, ensure the independence of each drug during storage, maintain the stability of the drug properties, prevent mutual reaction, and ensure that the two drugs are released in a predetermined ratio during inhalation to meet personalized treatment needs.

[0016] 2. In this inhalation drug delivery device, when the patient inhales the medicine, the two different types of medicines released from the capsule can be instantly mixed in the mixing tube, ensuring that the medicine inhaled by the patient is uniform, which significantly improves the treatment effect.

[0017] 3. The inhalation drug delivery device can conveniently and quickly cut off the top and bottom of the capsule through the cutting design of the upper and lower blades, thereby facilitating the release of the drug in the capsule. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a three-dimensional schematic diagram of the overall structure of the present invention; Figure 2 It is a cross-sectional view of the overall structure of the present invention; Figure 3 It is an enlarged schematic diagram of the horizontal plate part of the present invention; Figure 4 It is a front cross-sectional view of the housing portion of the present invention; Figure 5 is a cross-sectional view of a shell portion of the present invention; Figure 6 It is an enlarged schematic diagram of the branch pipe part of the present invention; Figure 7 It is an enlarged schematic diagram of the installation cylinder part of the present invention; Figure 8 is a cross-sectional view of a mixing tube portion of the present invention; Fig. 9 For the present invention Figure 5 A magnified schematic diagram of center A.

[0019] In the figure: 1. shell; 2. movable groove; 3. capsule; 4. partition; 5. fixed sleeve; 6. horizontal plate; 7. guide plate; 8. upper blade; 9. upper through groove; 10. lower blade; 11. lower through groove; 12. side opening; 13. medicine receiving groove; 14. suction groove; 15. medicine outlet pipe; 16. mixing pipe; 17. suction nozzle; 18. branch pipe; 19. side air groove; 20. baffle; 21. connecting column; 22. mounting cylinder; 23. annular absorbent cotton; 24. diaphragm; 25. column; 26. mounting plate; 27. fixing rod. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0021] Embodiment 1: See also Figure 1-Figure 8, an inhalation drug delivery device, comprising a capsule 3 for storing dry powder, such as Figure 3 As shown, a partition 4 is fixedly arranged in the capsule 3, and the partition 4 divides the internal space of the capsule 3 into an upper storage chamber and a lower storage chamber. Two different types of dry powder drugs can be stored through the upper storage chamber and the lower storage chamber. The partition 4 can ensure the independence of each drug during storage, maintain the stability of the drug properties, and prevent the two drugs from reacting with each other; In this embodiment, a transverse plate 6 is further provided, on which a plurality of fixing sleeves 5 adapted to the capsules 3 are evenly mounted. The inner wall of the fixing sleeve 5 is elastic, and the capsules 3 can be inserted into and tightly bound in the fixing sleeve 5, so that a plurality of capsules 3 can be arranged horizontally for easy use in sequence.

[0022] like Figure 4 As shown, a shell 1 is also provided, on which a moving groove 2 for allowing the capsule 3 to pass is opened transversely, so that the head end of the transverse plate 6 passes through the moving groove 2, and by pulling the transverse plate 6, multiple capsules 3 can pass through the moving groove 2 in sequence. Furthermore, two guide plates 7 are arranged opposite to each other on the side of the shell 1, which are used to guide the movement of the capsule 3 and the entry of the capsule 3 into the moving groove 2.

[0023] In the present invention, Figure 4 As shown, an upper cutter head 8 and a lower cutter head 10 are fixedly installed at the top and bottom of the movable groove 2, respectively. A side opening 12 corresponding to the length of the capsule 3 is also opened on one side of the movable groove 2 having the cutter heads of the upper cutter head 8 and the lower cutter head 10. The side opening 12 allows the cutter heads of the upper cutter head 8 and the lower cutter head 10 to be suspended in the air. When the capsule 3 passes through the movable groove 2, the upper cutter head 8 and the lower cutter head 10 can cut off the top and bottom ends of the capsule 3 respectively, thereby opening the capsule 3. The opened capsule 3 is located between the upper cutter head 8 and the lower cutter head 10. like Figure 4 As shown, a drug inhaler is installed on the top of the housing 1, the bottom end of the drug inhaler is connected to the movable groove 2 through the suction groove 14 and the upper through groove 9 on the upper cutter head 8, the drug receiving groove 13 is opened in the housing 1, and the top end is connected to the movable groove 2 through the lower through groove 11 on the lower cutter head 10; After opening, the capsule 3 is located between the upper cutting head 8 and the lower cutting head 10 , with the top end corresponding to the upper through groove 9 and the bottom end corresponding to the lower through groove 11 , thereby facilitating the discharge of dry powder, wherein the dry powder in the lower storage cavity of the capsule 3 will directly enter the medicine receiving groove 13 .

[0024] In the present invention, the medicine inhaler is composed of a medicine outlet pipe 15, a mixing pipe 16 and a suction nozzle 17 connected in sequence from top to bottom. The medicine outlet pipe 15 is fixedly installed on the top of the housing 1 and is connected to the suction groove 14. A branch pipe 18 is also provided, one end of which is connected to the medicine receiving groove 13 and the other end is connected to the medicine outlet pipe 15. In addition, a side air groove 19 is provided between the side wall of the suction groove 14 and the outside of the shell 1, and a vertical groove is provided at the bottom of the medicine receiving groove 13, and a one-way air inlet valve is provided in the vertical groove; Before use, first make the head end of the horizontal plate 6 pass through the moving groove 2, and then pull the horizontal plate 6 to make the capsule 3 enter the moving groove 2, and use the upper cutter head 8 and the lower cutter head 10 to cut off the top and bottom of the capsule 3 respectively to open the capsule 3. After opening, the top of the capsule 3 corresponds to the upper through groove 9, and the bottom corresponds to the lower through groove 11; When the patient inhales the medicine, he holds the inhalation nozzle 17 in his mouth and inhales forcefully. When he inhales, the inhalation groove 14 takes in air through the side air groove 19, and the medicine receiving groove 13 takes in air through the one-way air inlet valve. Then, by using negative pressure, the dry powder in the storage cavity of the capsule 3 can enter the mixing tube 16 through the upper through groove 9, the inhalation groove 14 and the medicine outlet pipe 15, and the dry powder in the medicine receiving groove 13 can enter the mixing tube 16 through the branch pipe 18 and the medicine outlet pipe 15. Two different types of medicines are mixed instantly in the mixing tube 16 and then inhaled by the patient through the inhalation nozzle 17, which can ensure that the medicine inhaled by the patient is uniform and significantly improve the treatment effect.

[0025] In the present invention, Figure 8 As shown, the mixing tube 16 is a spherical tube with a plurality of baffles 20 staggeredly installed inside. The baffles 20 can change the direction of the airflow, increase the collision and interaction between the dry powders, thereby improving the mixing uniformity. In addition, the baffles 20 will also force the dry powder to stay in the mixing tube 16 for a longer time, further facilitating the full mixing of the dry powder.

[0026] Of course, for those skilled in the art, the mixing tube 16 can also be designed as a spiral tube or an S-shaped tube to prolong the flow time and promote the smooth flow.

[0027] Embodiment 2: Based on the first embodiment, this embodiment further provides a specific structure of a one-way air intake valve, such as Fig. 9 As shown, the one-way air intake valve includes a diaphragm 24, a column 25, a mounting plate 26 and a fixing rod 27. A mounting plate 26 is fixedly mounted in the vertical groove by the fixing rod 27. The top of the mounting plate 26 is connected to the diaphragm 24 through the column 25, and the diaphragm 24 covers the top of the vertical groove. The diaphragm 24 can be opened only when the patient inhales, and is usually kept closed, thereby effectively preventing the dry powder in the medicine receiving slot 13 from leaking out, playing a one-way role; Of course, those skilled in the art may also select other forms of one-way valves as needed, and this is not too much limited in this embodiment.

[0028] like Figure 7As shown, a connecting column 21 is fixedly provided at the port of the side air groove 19, and a mounting cylinder 22 is threadedly connected to the connecting column 21. An annular absorbent cotton 23 is pushed and installed in the mounting cylinder 22. The annular absorbent cotton 23 can increase the humidity of the air entering the side air groove 19, thereby reducing the irritation of the dry powder to the patient's respiratory tract to a certain extent and improving the patient's comfort. Of course, the annular absorbent cotton 23 may be replaced with a heating ring to heat the air, or the baffle 20 in the mixing tube 16 may be directly designed as a heating plate.

[0029] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An inhalation drug delivery device, comprising a capsule (3) for storing dry powder, characterized in that: Also includes: A partition (4) is fixedly arranged in the capsule (3) to divide the internal space of the capsule (3) into an upper storage chamber and a lower storage chamber; A housing (1) having a movable groove (2) extending transversely therethrough for allowing the capsule (3) to pass therethrough; An upper cutter head (8) and a lower cutter head (10) are respectively fixedly mounted on the top and bottom of the movable groove (2); when the capsule (3) passes through the movable groove (2), the upper cutter head (8) and the lower cutter head (10) are respectively used to cut off the top and bottom of the capsule (3); The medicine inhaler is mounted on the top of the housing (1), and the bottom end is connected to the movable groove (2) through the suction groove (14) and the upper through groove (9) on the upper cutter head (8); A medicine receiving groove (13) is provided in the housing (1), and the top end thereof is connected to the movable groove (2) through a lower through groove (11) on the lower cutter head (10); One end of the branch pipe (18) is connected to the medicine receiving groove (13), and the other end is connected to the medicine inhaler.

2. An inhalation drug delivery device according to claim 1, characterized in that: It also comprises a transverse plate (6) on which fixing sleeves (5) matching the capsules (3) are evenly mounted, and the capsules (3) are inserted into and tightly bound in the fixing sleeves (5).

3. An inhalation drug delivery device according to claim 1, characterized in that: It also comprises two guide plates (7) arranged opposite to each other and fixedly mounted on the side of the housing (1) and used for guiding the capsule (3) to move and enter the moving groove (2).

4. An inhalation medication device according to claim 1, characterized in that: The movable groove (2) has a side of the upper cutting head (8) and the lower cutting head (10) having a side opening (12) corresponding to the length of the capsule (3), and the side opening (12) allows the cutting heads of the upper cutting head (8) and the lower cutting head (10) to be suspended in the air.

5. The inhalation drug delivery device according to claim 1, characterized in that: The drug inhaler is composed of a drug outlet pipe (15), a mixing pipe (16) and an inhalation nozzle (17) which are connected in sequence from top to bottom, wherein the drug outlet pipe (15) is fixedly mounted on the top of the housing (1) and is in communication with the inhalation groove (14); The upper end of the branch pipe (18) is in communication with the medicine outlet pipe (15).

6. An inhalation medication device according to claim 5, characterized in that: The mixing tube (16) is a spherical tube, and a plurality of baffles (20) are staggeredly installed inside.

7. An inhalation medication device according to claim 5, characterized in that: The mixing tube (16) is a spiral tube or an S-shaped tube.

8. An inhalation medication device according to claim 1, characterized in that: A side air groove (19) is provided between the side wall of the suction groove (14) and the outside of the shell (1).

9. An inhalation medication device according to claim 1, characterized in that: A vertical groove is provided at the bottom of the medicine receiving groove (13), and a one-way air inlet valve is provided in the vertical groove.

10. An inhalation medication device according to claim 9, characterized in that: The one-way air intake valve comprises a diaphragm (24), a column (25), a mounting plate (26) and a fixing rod (27); a mounting plate (26) is fixedly mounted in the vertical groove via the fixing rod (27); the top of the mounting plate (26) is connected to the diaphragm (24) via the column (25); and the diaphragm (24) covers the top of the vertical groove.

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