Radio frequency integrated circuit and radio frequency operating system

Abstract

The invention provides a radio frequency integrated circuit and a radio frequency operating system. The circuit comprises a main control module, a radio frequency ablation trigger module and a radio frequency cutting trigger module, the main control module outputs a first driving signal, a second driving signal and a cutting control signal; the radio frequency ablation trigger module alternately receives the first driving signal and the second driving signal and sequentially and alternately outputs radio frequency removal signals; the radio frequency removal signal comprises a radio frequency energy signal and a radio frequency ablation signal, and the radio frequency energy signal and the radio frequency ablation signal inactivate tumor cells in the target biological tissue; the radio frequency cutting trigger module receives the cutting control signal and outputs a radio frequency cutting signal, and the radio frequency cutting signal comprises a positive radio frequency cutting signal and a negative radio frequency cutting signal; and the positive radio frequency cutting signal and the negative radio frequency cutting signal cut the biological tissue to obtain a tissue sample and realize a blood coagulation function at the same time. The radio frequency cutting and the radio frequency ablation are combined, so that the integration of diagnosis and treatment can be realized, and the operation risk can be greatly reduced.

Description

Technical Field

[0001] The present application relates to the field of medical device technology, and in particular to a radio frequency integrated circuit and a radio frequency operating system. Background Art

[0002] With the rapid growth of cancer incidence, hospitals often use biopsy technology to help patients determine whether the cells in the examined area are cancerous. During the biopsy process, a rotary cutting system is usually used to repeatedly cut suspicious lesions and obtain tissue samples by vacuum suction and storage in a sample collection device.

[0003] Cancerous tissue resection surgery is one of the important means of treating cancer. Through biopsy and resection surgery, doctors can diagnose and treat cancer more accurately and improve patients' survival rate and quality of life. Summary of the invention

[0004] In view of this, the present application provides a radio frequency integrated circuit and a radio frequency operating system, which combine radio frequency cutting with radio frequency ablation to achieve integrated diagnosis and treatment, and can greatly reduce surgical risks.

[0005] Specifically, the technical solution of this application is as follows: In a first aspect, the present application provides a radio frequency integrated circuit, comprising: a radio frequency ablation trigger module, a radio frequency cutting trigger module and a main control module; The main control module is used to output a first drive signal, a second drive signal and a cutting control signal; The radio frequency ablation trigger module is connected to the main control module, and is used to alternately receive the first drive signal and the second drive signal, and alternately output radio frequency removal signals in sequence; the receiving time of the first drive signal is different from the driving time of the second drive signal, and the radio frequency removal signal includes a radio frequency energy signal and a radio frequency ablation signal, and the radio frequency energy signal and the radio frequency ablation signal are used to inactivate tumor cells in the target biological tissue; The RF cutting trigger module is connected to the main control module, and is used to receive the cutting control signal and output a RF cutting signal, wherein the RF cutting signal includes a positive RF cutting signal and a negative RF cutting signal; the positive RF cutting signal and the negative RF cutting signal are used to achieve coagulation function while cutting biological tissue.

[0006] In the second aspect, based on the same technical concept, the present application also provides a radio frequency operating system, including: a main body, a radio frequency cutting knife connected to the main body, a negative electrode plate, a radio frequency ablation electrode and the radio frequency integrated circuit described in the first aspect; the radio frequency cutting knife is used to receive a radio frequency cutting signal to cut biological tissue to obtain a tissue sample while realizing a coagulation function, the radio frequency ablation electrode is connected to the negative electrode plate to form a loop, the radio frequency ablation electrode is used to receive the radio frequency energy signal and the negative electrode plate is used to receive the radio frequency ablation signal, so as to inactivate tumor cells in the target biological tissue.

[0007] Compared with the prior art, the present application has at least one of the following beneficial effects: the present application has both radiofrequency cutting and radiofrequency ablation functions. Radiofrequency cutting can cut and obtain biological tissue to be tested to provide pathological diagnosis and detection and minimally invasive cutting to remove tumor sites, while radiofrequency ablation can directly treat tumors. The combination of the two can achieve seamless connection between diagnosis and treatment and realize the integration of diagnosis and treatment. According to the nature and size of the mass, the appropriate radiofrequency technology is selected (for example, fibroadenomas smaller than 3 cm can be treated with radiofrequency ablation technology, and radiofrequency cutting technology can cover different tumor sizes, and achieve sampling analysis and resection treatment), which can not only ensure the accuracy of diagnosis, but also provide effective treatment methods. BRIEF DESCRIPTION OF THE DRAWINGS

[0008] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For those skilled in the art, other drawings can be obtained based on these drawings without creative work.

[0009] Figure 1 It is a schematic diagram of the structure of an implementation of the radio frequency integrated circuit provided by the present application; Figure 2 It is a schematic diagram of the structure of an implementation of the radiofrequency ablation module provided by the present application; Figure 3 is a circuit diagram of a signal processing unit provided by the present application; Figure 4 is a circuit diagram of another signal processing unit provided by the present application; Figure 5 is a circuit diagram of a signal generating unit provided by the present application; Figure 6 It is a circuit diagram of the radio frequency cutting module provided in this application. DETAILED DESCRIPTION

[0010] The following will be combined with the accompanying drawings to clearly and completely describe the technical solutions in some embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments provided in this application, all other embodiments obtained by ordinary technicians in this field belong to the scope of protection of this application.

[0011] In the description of the present application, it should be understood that the terms "center", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0012] Unless the context requires otherwise, throughout the specification and claims, the term "including" is to be interpreted as an open, inclusive meaning, that is, "including, but not limited to". In the description of the specification, the terms "one embodiment", "some embodiments", "exemplary embodiments", "exemplarily" or "some examples" and the like are intended to indicate that specific features, structures, materials or characteristics associated with the embodiment or example are included in at least one embodiment or example of the present application. The schematic representation of the above terms does not necessarily refer to the same embodiment or example. In addition, the specific features, structures, materials or characteristics may be included in any one or more embodiments or examples in any appropriate manner.

[0013] In the following, the terms "first" and "second" are used for descriptive purposes only and are not to be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of the embodiments of the present application, unless otherwise specified, "plurality" means two or more.

[0014] When describing some embodiments, the expressions "coupled" and "connected" and their derivatives may be used. For example, when describing some embodiments, the term "connected" may be used to indicate that two or more components are in direct physical or electrical contact with each other. For another example, when describing some embodiments, the term "coupled" may be used to indicate that two or more components are in direct physical or electrical contact. However, the term "coupled" may also refer to two or more components that are not in direct contact with each other, but still cooperate or interact with each other. The embodiments disclosed herein are not necessarily limited to the contents of this document.

[0015] “At least one of A, B, and C” has the same meaning as “at least one of A, B, or C” and both include the following combinations of A, B, and C: A only, B only, C only, the combination of A and B, the combination of A and C, the combination of B and C, and the combination of A, B, and C.

[0016] “A and / or B” includes the following three combinations: A only, B only, and a combination of A and B.

[0017] Additionally, the use of “based on” is meant to be open and inclusive, as a process, step, calculation, or other action “based on” one or more stated conditions or values ​​may, in practice, be based on additional conditions or values ​​beyond those stated.

[0018] As used herein, "about," "substantially," or "approximately" includes the stated value and an average value that is within an acceptable range of variation from the particular value as determined by one of ordinary skill in the art taking into account the measurements in question and the errors associated with the measurement of the particular quantity (i.e., the limitations of the measurement system).

[0019] A tumor is a new organism formed by the abnormal proliferation of cells in local tissues under the action of various tumorigenic factors. Tumors can be divided into two categories: benign and malignant. Benign tumors are characterized by slow growth, clear boundaries, capsules, no invasion of surrounding tissues, no metastasis, and little impact on the body. Common types of benign tumors include lipomas, fibromas, hemangiomas, etc. Malignant tumors (cancer) are characterized by rapid growth, unclear boundaries, no capsules, can invade surrounding tissues and organs, can be transferred to other parts through the blood or lymphatic system, and are extremely harmful to the body. Common types of malignant tumors include lung cancer, breast cancer, gastric cancer, liver cancer, etc. Cancer lumps are locally palpable or observable solid lesions formed by malignant tumors. It is a common manifestation of malignant tumors, but not all lumps are cancer.

[0020] The rotary cutter in the biopsy system is a medical device used for minimally invasive surgery, mainly used for tissue biopsy and resection of breast, lung, liver and other parts. However, the rotary cutter usually achieves mechanical cutting by timing control of the motor to achieve the advance and retreat of the rotary cutter and the rotation of the rotary cutter. Mechanical cutting mainly depends on the design of the knife tube structure and the sharpness of the knife head. During the cutting process, it is limited by the knife tube structure. Due to the limitations of factors such as the diameter and length of the knife tube, the single cut tissue volume is small, and multiple cuts are required for sampling, which not only increases the operation time and complexity of the operation, but also may increase the risk of tissue damage. In addition, during the cutting process, the contact and cutting action of the knife head with the tissue can easily damage the blood vessels and cause bleeding. Bleeding not only affects the surgical field of view and increases the difficulty of the operation, but may also lead to the formation of postoperative hematoma. Postoperative hematoma will prolong the patient's recovery time, increase the patient's pain and medical costs, and in severe cases, further treatment may be required to remove the hematoma.

[0021] In order to solve the above problems, the present application provides a radio frequency integrated circuit and a radio frequency operating system, which combine radio frequency cutting with radio frequency ablation to achieve integrated diagnosis and treatment, and can greatly reduce surgical risks.

[0022] Please refer to Figure 1 , a radio frequency integrated circuit provided in the present application, the circuit comprises: a radio frequency ablation trigger module 200, a radio frequency cutting trigger module 300 and a main control module 100; The main control module 100 is used to output a first drive signal SPWMA, a second drive signal SPWMB and a cutting control signal; The radio frequency ablation trigger module 200 is connected to the main control module 100, and is used to alternately receive the first drive signal SPWMA and the second drive signal SPWMB, and alternately output radio frequency removal signals in sequence; the receiving time of the first drive signal SPWMA is different from the driving time of the second drive signal SPWMB, and the radio frequency removal signal includes a radio frequency energy signal and a radio frequency ablation signal, and the radio frequency energy signal and the radio frequency ablation signal are used to inactivate tumor cells in the target biological tissue; The RF cutting trigger module 300 is connected to the main control module 100, and is used to receive the cutting control signal and output a RF cutting signal, wherein the RF cutting signal includes a positive RF cutting signal DK-P and a negative RF cutting signal DK-N; the positive RF cutting signal DK-P and the negative RF cutting signal DK-N are used to realize the coagulation function while cutting biological tissue.

[0023] Specifically, the radio frequency integrated circuit of the present application has both radio frequency cutting and radio frequency ablation functions. Figure 1As shown, when it is necessary to cut the target biological tissue (i.e., the biological tissue with lesions such as a mass or tumor and the normal biological tissue within a certain range around it), the main control module 100 can send a cutting control signal AD0 to the RF cutting trigger module 300, so that the RF cutting trigger module 300 outputs a RF cutting signal including a positive RF cutting signal DK-P and a negative RF cutting signal DK-N according to the cutting control signal AD0, and the RF cutting signal is transmitted to the RF cutting knife to cut the target biological tissue and realize the coagulation function at the same time. Alternatively, when it is necessary to clarify whether the biological tissue to be tested has the nature of a mass or tumor, the main control module 100 can send a cutting control signal AD0 to the RF cutting trigger module 300, so that the RF cutting trigger module 300 outputs a RF cutting signal including a positive RF cutting signal DK-P and a negative RF cutting signal DK-N according to the cutting control signal AD0, and the RF cutting signal is transmitted to the RF cutting knife to cut the biological tissue to obtain a tissue sample and realize the coagulation function at the same time, and the tissue is cut and removed by the RF cutting function for further laboratory diagnosis. For smaller masses or tumors, radiofrequency ablation is used, that is, the main control module 100 can send the first drive signal SPWMA and the second drive signal SPWMB to the radiofrequency ablation trigger module 200 alternately and in time, so that the radiofrequency ablation trigger module 200 outputs a radiofrequency removal signal including a radiofrequency energy signal and a radiofrequency ablation signal according to the first drive signal SPWMA or the second drive signal SPWMB, the radiofrequency energy signal is transmitted to the negative plate and the radiofrequency ablation signal is transmitted to the radiofrequency ablation electrode, the radiofrequency ablation electrode and the negative plate form a loop in the biological body, and the thermal effect generated by the radiofrequency energy signal causes the target biological tissue to generate high temperature and dryness, and finally coagulates and inactivates the target biological tissue, so as to cause coagulative necrosis of the tumor cells in the target biological tissue, thereby achieving the purpose of inactivating the tumor cells.

[0024] The radiofrequency cutting of the present application can cut and obtain the biological tissue to be examined to provide pathological diagnosis and detection, as well as minimally invasive cutting to remove the tumor site, while radiofrequency ablation can directly treat the tumor. The combination of the two can achieve seamless connection between diagnosis and treatment, and realize the integration of diagnosis and treatment. According to the nature and size of the tumor, choosing the appropriate radiofrequency technology can not only ensure the accuracy of diagnosis, but also provide effective treatment methods.

[0025] In some embodiments, Figure 2 As shown, the radiofrequency ablation trigger module 200 includes: Two signal processing units 210, the two signal processing units 210 have the same structure, one of the two signal processing units 210 is used to receive the first drive signal SPWMA and output a first ablation switch control signal DRVA, and the other of the two signal processing units 210 is used to receive the second drive signal SPWMB and output a second ablation switch control signal DRVB; The signal generating unit 220 is connected to the signal processing unit 210, and is used to receive the AC voltage signal, and output the RF energy signal and the RF ablation signal according to the received first ablation switch control signal DRVA and the AC voltage signal, or output the RF energy signal and the RF ablation signal according to the received second ablation switch control signal DRVB and the AC voltage signal.

[0026] Specifically, two signal processing units 210 with the same structure alternately receive the first drive signal SPWMA and the second drive signal SPWMB, and the two signal processing units 210 work alternately, that is, one of the two signal processing units 210 receives the first drive signal SPWMA and outputs the first ablation switch control signal DRVA at a certain moment, and the other signal processing unit 210 of the two signal processing units 210 does not work at this time, and the other signal processing unit 210 of the two signal processing units 210 receives the second drive signal SPWMB and outputs the second ablation switch control signal DRVB at another moment, and the other signal processing unit 210 of the two signal processing units 210 does not work at this time. The two signal generating units 220 are both connected to the signal processing unit 210. The signal generating unit 220 receives the AC voltage signal and the first ablation switch control signal DRVA or the second ablation switch control signal DRVB respectively sent by the two signal generating units 220 in a time-sharing manner, and outputs the radio frequency energy signal and the radio frequency ablation signal according to the received first ablation switch control signal DRVA and the AC voltage signal, or outputs the radio frequency energy signal and the radio frequency ablation signal according to the received second ablation switch control signal DRVB and the AC voltage signal. The two signal processing units 210 with the same structure are like two "signal converters" working alternately, converting the input first drive signal SPWMA (or the second drive signal SPWMB) into the first ablation switch control signal DRVA (or the second ablation switch control signal DRVB). The two signal processing units 210 work in turn to ensure that the required ablation switch control signal (including the first ablation switch control signal DRVA and the second ablation switch control signal DRVB) can be continuously and stably output, so that the signal generating unit 220 generates the radio frequency energy signal and the radio frequency ablation signal according to the received ablation switch control signal and the AC voltage signal.

[0027] In some embodiments, Figure 3 and Figure 4 As shown, one of the signal processing units includes a first driver U46 and a first transistor Q9, and another of the signal processing units includes a second driver U47 and a second transistor Q10; The input terminal p2 of the first driver U46 is connected to the first drive signal SPWMA, the voltage terminal of the first driver U46 is connected to the first power supply 12V, the ground terminal of the first driver U46 is grounded, the output terminal of the first driver U46 is connected to the control electrode 1 of the first transistor Q9, the first electrode 3 of the first transistor Q9 is grounded, and the second electrode 2 of the first transistor Q9 is used to output the first ablation switch control signal DRVA; The input terminal p2 of the second driver U47 is connected to the second drive signal SPWMB, the voltage terminal of the second driver U47 is connected to the first power supply +12V, the ground terminal of the first driver U46 is grounded, the output terminal of the second driver U47 is connected to the control electrode 1 of the second transistor Q10, the first electrode 3 of the second transistor Q10 is grounded, and the second electrode 2 of the second transistor Q10 is used to output the second ablation switch control signal DRVB.

[0028] Specifically, one of the two signal processing units includes a first driver U46, a first transistor Q9, a second capacitor C219, a third capacitor C217, a fourth capacitor C221, a first electrolytic capacitor E1, a first inductor L17, a sixth resistor R196, a seventh resistor R187, an eighth resistor R193, a ninth resistor R198, a tenth resistor R189, an eleventh resistor R190, a third diode D28, and a fourth diode D30; The input terminal p2 of the first driver U46 is connected to the first driving signal SPWMA, the first voltage terminal p1 of the first driver U46 is connected to the second voltage terminal p8 of the first driver U46, the first voltage terminal p1 of the first driver U46 is also connected to one end of the first electrolytic capacitor E1, one end of the second capacitor C219 and one end of the third capacitor C217, the other end of the first electrolytic capacitor E1, the other end of the second capacitor C219 and the other end of the third capacitor C217 are all grounded, the other end of the third capacitor C217 is also connected to one end of the first inductor L17, and the other end of the first inductor L17 is connected to the first power supply +12V; The first ground terminal p4 of the first driver U46 is connected to one end of the sixth resistor R196, one end of the sixth resistor R196 is grounded, the other end of the sixth resistor R196 is connected to the input terminal p2 of the first driver U46, the second ground terminal p5 of the first driver U46 is connected to the first electrode 3 of the first transistor Q9, and the first electrode 3 of the first transistor Q9 is grounded; The first output terminal p6 of the first driver U46 is connected to the second output terminal p7 of the first driver U46, and the first output terminal p6 of the first driver U46 is also connected to the cathode of the third diode D28, and the anode of the third diode D28 is connected to one end of the seventh resistor R187; The second output terminal p7 of the first driver U46 is also connected to one end of the eighth resistor R193, the other end of the eighth resistor R193 is connected to the other end of the seventh resistor R187 and the control electrode 1 of the first transistor Q9, and the ninth resistor R198 is connected between the control electrode 1 of the first transistor Q9 and the first electrode 3 of the first transistor Q9; The second electrode 2 of the first transistor Q9 is connected to one end of the fourth capacitor C221 and outputs the first switch control signal, the other end of the fourth capacitor C221 is connected to the anode of the fourth diode D30, one end of the tenth resistor R189 and one end of the eleventh resistor R190, and the cathode of the fourth diode D30, the other end of the tenth resistor R189 and the other end of the eleventh resistor R190 are connected to the first electrode 3 of the first transistor Q9; Another signal processing unit includes: a second driver U47, a fifth capacitor C218, a sixth capacitor C220, a seventh capacitor C222, a second electrolytic capacitor E2, a second inductor L18, a twelfth resistor R197, a thirteenth resistor R188, a fourteenth resistor R195, a fifteenth resistor R199, a sixteenth resistor R191, a seventeenth resistor R192, a fifth diode D29, a sixth diode D31 and a second transistor Q10; The input terminal p2 of the second driver U47 is connected to the second drive signal SPWMB, the first voltage terminal p1 of the second driver U47 is connected to the second voltage terminal p8 of the second driver U47, the first voltage terminal p1 of the second driver U47 is also connected to one end of the second electrolytic capacitor E2, one end of the fifth capacitor C218 and one end of the sixth capacitor C220, the other end of the second electrolytic capacitor E2, the other end of the fifth capacitor C218 and the other end of the sixth capacitor C220 are all grounded, the other end of the sixth capacitor C220 is also connected to one end of the second inductor L18, and the other end of the second inductor L18 is connected to the first power supply +12V; The first ground terminal p4 of the second driver U47 is connected to one end of the twelfth resistor R197, one end of the twelfth resistor R197 is grounded, the other end of the twelfth resistor R197 is connected to the input terminal p2 of the second driver U47, and the second ground terminal p5 of the second driver U47 is connected to the first electrode 3 of the second transistor Q10, and the first electrode 3 of the second transistor Q10 is grounded; The first output terminal p6 of the second driver U47 is connected to the second output terminal p7 of the second driver U47, and the first output terminal p6 of the second driver U47 is also connected to the cathode of the fifth diode D29, and the anode of the fifth diode D29 is connected to one end of the thirteenth resistor R188; The second output terminal p7 of the second driver U47 is also connected to one end of the fourteenth resistor R195, the other end of the fourteenth resistor R195 is connected to the other end of the thirteenth resistor R188 and the control electrode 1 of the second transistor Q10, and the fifteenth resistor R199 is connected between the control electrode 1 of the second transistor Q10 and the first electrode 3 of the second transistor Q10; The second electrode 2 of the second transistor Q10 is connected to one end of the seventh capacitor C222 and outputs the second switch control signal, the other end of the seventh capacitor C222 is connected to the anode of the sixth diode D31, one end of the sixteenth resistor R191 and one end of the seventeenth resistor R192, the cathode of the sixth diode D31, the other end of the sixteenth resistor R191 and the other end of the seventeenth resistor R192 are all connected to the first electrode 3 of the second transistor Q10.

[0029] The models of the first driver U46 and the second driver U47 may be TC4420, and the models of the first transistor Q9 and the second transistor Q10 may be IRFP250.

[0030] In some embodiments, Figure 5As shown, the signal generating unit 220 includes a first transformer T3, a first multi-stage filter 221, a first filtering sub-unit 222 and a second filtering sub-unit 223; The first interface c1 of the first transformer T3 is connected to the first ablation switch control signal, the third interface c3 of the first transformer T3 is connected to the second ablation switch control signal, and the second interface c2 of the first transformer T3 is connected to the AC voltage signal; The fifth interface c5 of the first transformer T3 is connected to the first input end of the first multi-stage filter 221, and the fourth interface c4 of the first transformer T3 is connected to the second input end of the first multi-stage filter 221; The first output end of the first multi-stage filter 221 is connected to the first end of the first filter subunit 222, and the second end of the first filter subunit 222 outputs the radio frequency ablation signal. The second output end of the first multi-stage filter 221 is connected to the first end of the second filter subunit 223, and the second end of the second filter subunit 223 outputs the radio frequency energy signal.

[0031] Specifically, Figure 5 As shown, the first multi-stage filter 221 can be composed of LC (L stands for Inductor, C stands for Capacitor) filters. Since the capacitor exhibits high impedance at low frequencies and low impedance at high frequencies; the inductor exhibits low impedance at low frequencies and high impedance at high frequencies. Therefore, when the capacitor is connected in parallel and in series with the inductor to form an LC filter, the capacitor is responsible for bypassing the high-frequency noise and directing it to the ground; the inductor prevents the high-frequency signal from passing through, thereby suppressing the high-frequency noise, while allowing the low-frequency or DC signal to pass through. Although a single-stage LC filter (such as a simple CL or LC structure) can filter out some high-frequency noise, its filtering effect is limited. Therefore, the first multi-stage filter 221 of the present application is a multi-stage LC filter, specifically an extended form of a π-type (CLC) filter, such as Figure 5 As shown in the figure, an inductor is connected in series between two sets of parallel capacitors, which can significantly improve the attenuation effect of high-frequency noise, have better high-frequency suppression ability, and make the output signal purer. By adjusting the parameters of multiple inductors and multiple capacitors in the multi-stage LC filter, different types of filters (such as low-pass, high-pass, band-pass, etc.) can be designed with flexible frequency selectivity to meet different application scenarios. In addition, the multi-stage filter can effectively suppress harmonic components, reduce harmonic interference, and avoid interference with the circuit. Moreover, the multi-stage LC filter can better handle complex signals and improve the performance and reliability of the system.

[0032] The first multi-stage filter 221 is used to select signals within a specific frequency range, remove unnecessary frequency components, and purify the signal: through multi-stage filtering, reduce noise and interference in the signal, ensure the purity of the output signal, and distribute the processed signal to different filtering sub-units. The first filtering sub-unit 222 performs more refined filtering processing on the signal output from the first multi-stage filter 221, and finally outputs a radiofrequency ablation signal to ensure that it meets the requirements of the treatment device. The second filtering sub-unit 223 performs more refined filtering processing on the signal output from the first multi-stage filter 221, and finally outputs a radiofrequency energy signal to ensure that it meets the requirements of the treatment device.

[0033] The RF ablation signal Negative is the negative polarity signal of the system. It is connected to the negative plate to form a current loop, disperse energy, and ensure that the RF energy returns to the device safely. The RF energy signal RF is the core output signal of the RF ablation system. It transmits high-frequency energy to the lesion site through the RF ablation electrode to heat and ablate the lesion tissue. These two signals cooperate with each other in the RF ablation system to ensure that the RF energy can be safely and effectively transmitted to the lesion site to complete the treatment process. In the RF ablation system, the RF current needs to form a complete loop through the human tissue. The RF ablation signal is attached to the surface of the human body through the negative plate, and together with the RF ablation electrode (RF electrode), it forms the return path of the current. The function of the negative plate is to safely guide the RF energy from the human tissue back to the device, thereby completing the closed loop of the current. The RF ablation signal ensures that the RF energy can return to the device safely, prevents energy leakage or unnecessary accumulation in the human body, and thus ensures the safety of treatment. The radiofrequency ablation signal is a high-frequency signal (480kHz) that has been filtered and rectified. It is transmitted to the lesion site through the radiofrequency ablation electrode. This high-frequency energy causes the polar molecules and ions in the lesion tissue to vibrate and rub, thereby generating heat energy. The generated heat energy will increase the temperature of the local tissue of the lesion, causing irreversible thermal coagulation and denaturation of tissue cell proteins, and ultimately causing tissue necrosis, achieving the purpose of ablating the lesion. The radiofrequency ablation signal acts directly on the lesion through the radiofrequency ablation electrode, which can achieve precise heating and ablation of the lesion while minimizing damage to the surrounding normal tissue.

[0034] In conclusion, this application Figure 3 The first transistor Q9 (or Figure 4 The second transistor Q10) will pass Figure 3 The first driver U46 (or Figure 4 The second driver U47 shown in the figure receives the 480kHz first drive signal (or the second drive signal) and then amplifies the output signal to ensure that there is sufficient power output to output Figure 3 The first ablation switch control signal DRVA (or Figure 4The second ablation switch control signal DRVB is shown). Then, Figure 5 The first transformer T3, the first multi-stage filter 221, the first filter subunit 222 and the second filter subunit 223 shown in the figure process the amplified signal, remove unnecessary high-frequency noise and clutter, ensure the purity of the output signal, and finally output a 480kHz high-frequency radio frequency energy signal and radio frequency ablation signal. Both the radio frequency energy signal and the radio frequency ablation signal are high-frequency sinusoidal wave signals. Through the radio frequency ablation electrode and the negative plate, a loop is formed in the human body, so that the polar molecules and ions in the lesion tissue vibrate and rub, and are converted into heat energy, thereby achieving the purpose of ablating the lesion. The output form of the high-frequency sinusoidal wave signal of the present application, combined with the software control algorithm, can accurately control the output power and frequency of the radio frequency energy, ensuring the safety and effectiveness of the ablation process.

[0035] In some embodiments, the radiofrequency ablation trigger module 200 further includes: A detection feedback unit, connected to the first multi-stage filter 221, used for sampling and outputting the ablation feedback voltage VSEN and the ablation feedback current ISEN to the main control module 100; The main control module 100 adjusts the magnitude of the AC voltage signal connected to the signal generating unit 220 according to the ablation feedback voltage VSEN and the ablation feedback current ISEN.

[0036] Specifically, a detection feedback unit is set in the radiofrequency ablation trigger module 200 to sample the ablation feedback voltage VSEN and current in real time, and transmit this information to the main control module 100. The main control module 100 adjusts the size of the AC voltage signal of the signal generating unit 220 according to these feedback signals, thereby achieving precise power control. This closed-loop control method can effectively reduce the power fluctuation caused by load changes or other interference factors, ensure that the ablation device operates stably at the set power, and improve the control accuracy. The feedback mechanism of the detection feedback unit is set in the radiofrequency ablation trigger module 200, which can quickly respond to changes in the load and avoid poor ablation effect or equipment damage caused by unstable power. For example, during the radiofrequency ablation process, the tissue impedance may change, and the feedback unit can detect this change in time, and adjust the output power through the main control module 100, so as to maintain a stable ablation effect and strengthen the stability and reliability of the system. In summary, the application of the detection feedback unit in the radiofrequency ablation device can not only improve the control accuracy and stability of the device, but also optimize the overall performance, providing more reliable protection for ablation treatment.

[0037] In some embodiments, Figure 5 As shown, the detection feedback unit includes a second transformer T1 and a third transformer T2; The fourth interface c4 of the second transformer T1 is connected to the first output end of the first multi-stage filter 221, and the third interface c3 of the second transformer T1 is connected to the second output end of the first multi-stage filter 221; The second interface c2 of the second transformer T1 is connected to a voltage sensor to detect and obtain the ablation feedback voltage VSEN, and the first interface c1 of the second transformer T1 is connected to a voltage feedback terminal of the main control module 100 to output the ablation feedback voltage VSEN to the main control module 100; The third interface c3 of the third transformer T2 is connected to the fourth interface c4 of the second transformer T1, and the fourth interface c4 of the third transformer T2 is connected to the first end of the first filtering subunit 222; The second interface c2 of the third transformer T2 is connected to a current sensor to detect and obtain the ablation feedback current ISEN, and the first interface c1 of the third transformer T2 is connected to a current feedback terminal of the main control module 100 to output the ablation feedback current ISEN to the main control module 100 .

[0038] Specifically, Figure 5 As shown, the second transformer T1 and the third transformer T2 respectively monitor the voltage and current of the ablation output to obtain the ablation feedback voltage VSEN and the ablation feedback current ISEN, and transmit the ablation feedback voltage VSEN and the ablation feedback current ISEN to the main control module 100. The main control module 100 adjusts the size of the AC voltage signal connected to the signal generating unit 220 according to the ablation feedback voltage VSEN and the ablation feedback current ISEN.

[0039] The voltage and current of the ablation output are monitored by the second transformer T1 and the third transformer T2 respectively, and the ablation feedback voltage VSEN and the ablation feedback current ISEN are obtained, and then transmitted to the main control module 100. After receiving the ablation feedback voltage VSEN and the current, the main control module 100 will perform a series of processing. For example, a digital filter is used to remove noise and improve the quality of the feedback signal. Then, by calculating the active power and other methods, the calculated power obtained by calculating the ablation feedback voltage VSEN and the ablation feedback current ISEN is compared with the preset target parameters (such as the target power). According to the comparison results, the main control module 100 decides how to adjust the size of the AC voltage signal. If the calculated power is higher than the target power, the AC voltage signal is reduced; if it is lower than the target power, the AC voltage signal is increased. In this application, the ablation feedback voltage VSEN and the ablation feedback current ISEN are used as feedback signals of the closed-loop control system, which can reflect the actual state of the ablation process in real time, so that the main control module 100 can dynamically adjust the AC voltage signal to ensure the stability and safety of the ablation process. In summary, by detecting the feedback unit to obtain the ablation feedback voltage VSEN and the ablation feedback current ISEN, the main control module 100 can monitor the ablation process in real time and adjust the size of the AC voltage signal according to the feedback signal, thereby achieving precise control of the power of the radio frequency ablation signal output during the ablation process and the power of the radio frequency capacity cycle.

[0040] In some embodiments, the radiofrequency ablation trigger module 200 further includes: The self-check protection unit is connected to the main control module 100, and is used to detect the circuit according to the self-check trigger signal RLY0 sent by the main control module 100, and switch to the protection mode to absorb the counter-attack voltage when the self-check trigger signal RLY0 is not received.

[0041] Specifically, since the circuit involves high power requirements and is prone to generate a counter-attack voltage (such as a voltage spike caused by an inductive load), a self-test protection unit is set in the radiofrequency ablation trigger module 200. The self-test protection unit can switch to a protection mode when the self-test trigger signal RLY0 is not received, and prevents the circuit components from being damaged by absorbing the counter-attack voltage, thereby extending the service life of the device. In medical equipment, safety is of vital importance. Setting a self-test protection unit can ensure that the device will not cause harm to the patient or operator due to circuit failure or abnormality during operation, thereby ensuring operational safety. In addition, the self-test protection unit can detect the circuit according to the self-test trigger signal RLY0 sent by the main control module 100. This regular or real-time detection can promptly detect potential faults, such as short circuits, open circuits, or component damage, so that measures can be taken in advance to avoid sudden failure of the device during operation. In addition, through the self-test function, the device can automatically check its own status before startup or during operation to ensure that all functions are normal, which can effectively reduce misoperation caused by equipment failure and improve the overall reliability of the device. Through the protection function of the self-check protection unit, the failure rate of the equipment will be significantly reduced, thereby reducing the number of maintenance times and maintenance costs. In addition, the self-check protection unit can send a feedback signal to the main control module 100 when a fault is detected, helping maintenance personnel to quickly locate the fault point and shorten the maintenance time. The self-check protection unit realizes the automatic detection function, reduces the need for manual detection, and improves the intelligence of the equipment. In addition, the main control module 100 can monitor the equipment status in real time according to the feedback signal of the self-check protection unit, and adjust the operating parameters or take protective measures in time. In the medical field, the safety and reliability of equipment must comply with strict regulations and standards. The setting of the self-check protection unit helps the equipment meet these requirements and ensure that the equipment can pass relevant certification. In addition, equipment with self-check protection function can bring users (such as doctors and patients) a higher sense of trust and improve user trust. The self-check protection unit can ensure that the circuit state of the radiofrequency ablation device is good during operation, thereby ensuring the stable output of radiofrequency energy and improving the treatment effect. By absorbing the counter-attack voltage and preventing circuit abnormalities, the self-check protection unit can reduce electromagnetic interference to other circuits or equipment and improve the performance of the equipment. In short, the setting of the self-test protection unit can not only significantly improve the safety and reliability of the radiofrequency ablation equipment, but also reduce maintenance costs, enhance the level of intelligence, and meet the regulatory requirements for medical devices.

[0042] In some embodiments, Figure 5 As shown, the self-check protection unit includes a third transistor Q11, a first diode CR3, a first resistor R181, a second resistor R182, a third resistor R180 and a relay switch K3; The first electrode 3 of the third transistor Q11 is grounded, the control electrode 1 of the third transistor Q11 is connected to the self-test control terminal of the main control module 100 to receive the self-test trigger signal RLY0, and the second electrode 2 of the third transistor Q11 is connected to the anode of the first diode CR3; The anode of the first diode CR3 is connected to the first contact d1 of the relay switch K3, and the cathode of the first diode CR3 is connected to the first power supply +12V and the second contact d8 of the relay switch K3; The third resistor R180 is connected between the third contact d2 of the relay switch K3 and the fourth contact d7 of the relay switch K3, the second resistor R182 is connected between the first movable contact d3 of the relay switch K3 and the fifth contact d4 of the relay switch K3, the first resistor R181 is connected between the sixth contact d5 of the relay switch K3 and the second movable contact d6 of the relay switch K3; the first movable contact d3 is arranged between the third contact d2 and the fifth contact d4, and the second movable contact d6 is arranged between the fourth contact d7 and the sixth contact d5; When the control electrode 1 of the third transistor Q11 receives the self-test trigger signal RLY0, the second movable contact d6 is connected to the fourth contact d7, and the first movable contact d3 is connected to the third contact d2; When the control electrode 1 of the third transistor Q11 does not receive the self-test trigger signal RLY0 , the second movable contact d6 is connected to the sixth contact d5 , and the first movable contact d3 is connected to the fifth contact.

[0043] Specifically, the main control module 100 sends a self-test trigger signal RLY0 to the control electrode 1 of the third transistor Q11. When the self-test trigger signal RLY0 is received, the third transistor Q11 is turned on, and the contact state of the relay switch K3 changes. Specifically, the second active contact d6 is connected to the fourth contact d7, and the first active contact d3 is connected to the third contact d2. In the self-test mode, a specific detection loop is formed by the contact connection state of the relay switch K3. At this time, the main control module 100 can determine whether the circuit is normal by monitoring the current, voltage or other parameters in the circuit. For example: If there is a short circuit or open circuit in the circuit, the main control module 100 will detect an abnormal current or voltage value. If the circuit is normal, the main control module 100 will receive the expected feedback signal.

[0044] When the self-test trigger signal RLY0 is not received, the third transistor Q11 is turned off, the contact state of the relay switch K3 is switched to the protection mode, and the contact state of the relay switch K3 changes. Specifically, the second active contact d6 is connected to the sixth contact d5, and the first active contact d3 is connected to the fifth contact d4. Since a counter-attack voltage is generated at the moment of the relay contact closing, this voltage may exceed the withstand voltage value of the components in the circuit. The counter-attack voltage will not only damage other components in the circuit, but may also have an adverse effect on the relay contacts themselves, thereby damaging the circuit. In the protection mode, the circuit absorbs the energy of the counter-attack voltage through the first resistor R181 and the second resistor R182, and limits the voltage within a safe range, thereby protecting the components in the circuit. By absorbing the counter-attack voltage, the service life of the relay contacts can be extended to prevent circuit damage. In addition, by absorbing the counter-attack voltage, the system can reduce malfunctions or failures due to voltage spikes, which helps to improve the overall reliability of the system and ensure that the system remains stable during long-term operation.

[0045] The third transistor Q11, the first diode CR3, the first resistor R181, the second resistor R182, the third resistor R180 and the relay switch K3 in the self-check protection unit play a key role in the self-check and protection process. For example, the first diode CR3 can prevent the current from flowing in the opposite direction, while the resistor is used to limit the current and absorb energy. Through the above mechanism, the self-check protection unit can realize self-check of the radiofrequency ablation trigger module 200, and switch to the protection mode when the self-check trigger signal RLY0 is not received, so as to ensure the safe operation of the circuit. Among them, the model of the relay switch K3 can be RT424012F, and the model of the third transistor Q11 can be VN2222LLRLRAG.

[0046] In some embodiments, Figure 5 As shown, the self-test protection unit may further include a fourth resistor R185, a fifth resistor R186 and a first capacitor C96, one end of the fourth resistor R185 is connected to the self-test trigger signal, the other end of the fourth resistor R185 is respectively connected to one end of the fifth resistor R186 and the control electrode 1 of the third transistor Q11, the other end of the fifth resistor R186 is connected to the first electrode 3 of the third transistor Q11, and the other end of the fifth resistor R186 is grounded, one end and the other end of the first capacitor C96 are respectively connected to the cathode and anode of the first diode CR3, one end of the first capacitor C96 is also connected to the second contact d8 of the relay switch K3, and the other end of the first capacitor C96 is also connected to the first contact d1 of the relay switch K3.

[0047] In some embodiments, Figure 6As shown, the RF cutting trigger module 300 includes a fourth transistor Q3, a fifth transistor Q4, a fourth transformer T4, a fifth transformer T5, a second diode CR1, a choke coil Z1, a second multi-stage filter, a first connector J3, a second connector J4 and a voltage regulator U6; The first electrode 33 of the fifth transistor Q4 is grounded through a resistor and a capacitor, the second electrode 22 of the fifth transistor Q4 is connected to the second interface c2 of the fifth transformer T5, and the control electrode 11 of the fifth transistor Q4 is connected to the cutting control signal AD0; The first interface c1 of the fifth transformer T5 is connected to the first power supply, the third interface c3 of the fifth transformer T5 is connected to the power ground, and the fourth interface c4 of the fifth transformer T5 is respectively connected to the cathode of the second diode CR1, one end of the choke coil Z1 and the control electrode 1 of the fourth transistor Q3; The other end of the choke coil Z1 is connected to the output voltage regulating end of the voltage regulator U6 and the voltage output end of the voltage regulator U6, and the voltage end of the voltage regulator U6 is connected to the second power supply 7.5V; The first electrode 3 of the fourth transistor Q3 is connected to the second electrode 2 of the fourth transistor Q3, and the second electrode 2 of the fourth transistor Q3 is connected to the second interface c2 of the fourth transformer T4; The first interface c1 of the fourth transformer T4 is connected to the third power supply 50V, the fourth interface c4 of the fourth transformer T4 is connected to the first input end of the second multi-stage filter, the third interface c3 of the fourth transformer T4 is connected to the second input end of the second multi-stage filter, the first output end of the second multi-stage filter is connected to the first connector J3 to output the negative RF cutting signal DK-N, and the second output end of the second multi-stage filter is connected to the second connector J4 to output the positive RF cutting signal DK-P.

[0048] Specifically, the RF cutting trigger module 300 receives the cutting control signal AD0 from the main control module 100, and triggers the entire circuit to work through the control electrode 1 of the fifth transistor Q4. The RF cutting trigger module 300 outputs a RF cutting signal, including a positive RF cutting signal DK-P and a negative RF cutting signal DK-N, and the positive RF cutting signal DK-P and the negative RF cutting signal DK-N are output through the first connector J3 and the second connector J4. When the main control module 100 sends a cutting control signal AD0, the fifth transistor Q4 is activated, and the current passes through the fifth transformer T5. The fourth end of the fifth transformer T5 adjusts the voltage through the choke coil Z1 and the voltage regulator U6 to provide a stable power supply for the subsequent circuit. The fourth transformer T4 receives the third power supply 50V and converts it into a RF signal through its winding. The second multi-stage filter filters the RF signal to ensure the purity and stability of the output signal. The RF signal after filtering by the second multi-stage filter is divided into a positive RF cutting signal DK-P and a negative RF cutting signal DK-N, which are output through the first connector J3 and the second connector J4, respectively. The cutting and coagulation of biological tissues are achieved through high-frequency current, thereby improving the safety and efficiency of the operation. The negative RF cutting signal DK-N is mainly used for low-temperature cutting. The water molecules in the tissue are oscillated to generate heat through RF energy, thereby achieving fine cutting of the tissue. The positive RF cutting signal DK-P is mainly used for coagulation function. The protein in the tissue is denatured by high-frequency current to achieve hemostasis. In some RF surgeries, the negative RF cutting signal DK-N and the positive RF cutting signal DK-P can be used at the same time to achieve the dual functions of cutting and coagulation. For example, in the design of some RF cutting biopsy needles, by adjusting the waveform and frequency of the RF energy, the coagulation effect can be achieved while cutting. However, in some specific surgical scenarios, only the negative RF cutting signal DK-N may be used for low-temperature cutting to reduce thermal damage to surrounding tissues. The present application can flexibly switch or simultaneously output the negative RF cutting signal DK-N and the positive RF cutting signal DK-P according to surgical requirements. For example, some RF cutting knives can achieve a partial rectification waveform during the cutting process by adjusting the waveform of the RF energy, and perform cutting and hemostasis at the same time.

[0049] Among them, the model of the fourth transistor Q3 can be BLW96, the model of the fifth transistor Q4 can be MJE200G, the model of the voltage regulator U6 can be LM317ATP+, and the model of the choke coil Z1 can be WBR6H-3T-H6A.

[0050] The differences between radiofrequency cutting and radiofrequency ablation in treatment are mainly reflected in the following aspects: 1. Treatment principle: Radiofrequency cutting is mainly used to cut tissues through high-frequency current, while using the thermal effect of radiofrequency electrodes to achieve coagulation function to reduce bleeding during surgery.

[0051] Radiofrequency ablation uses radiofrequency energy to cause high-frequency vibration of ions in tumor tissue to generate heat. The local temperature can reach 60°C~120°C, which causes tumor cell dehydration, protein denaturation, and ultimately coagulative necrosis, achieving the purpose of inactivating the tumor in situ.

[0052] 2. Applicable situations: Radiofrequency cutting is mainly used in situations where tissue needs to be removed to obtain pathological samples or for surgical resection. It is suitable for scenarios where the nature of a tumor needs to be clarified or a larger tumor needs to be removed.

[0053] Radiofrequency ablation is mainly used for smaller breast cancers (such as localized breast cancer with a diameter of ≤2 cm) or patients who are not suitable for surgery (such as the elderly, the frail, or those with serious underlying diseases), as well as patients who need to preserve the appearance of the breast.

[0054] 3. Therapeutic effects and characteristics: The advantage of radiofrequency cutting is that it can accurately remove diseased tissue and achieve coagulation during the cutting process, reducing intraoperative bleeding.

[0055] The advantages of radiofrequency ablation are minimally invasive, quick recovery, and no scars. It can also effectively kill tumor cells with minimal damage to surrounding normal tissues.

[0056] 4. Postoperative recovery: The recovery time after radiofrequency cutting is relatively long and may require suturing and a certain recovery period.

[0057] Radiofrequency ablation has a short recovery time after surgery, usually does not require sutures, and patients can return to their normal lives in a short period of time.

[0058] 5. Indications: Radiofrequency ablation is indicated when a histopathological diagnosis is required or when resection of larger tumors is necessary.

[0059] Radiofrequency ablation is suitable for early breast cancer, benign tumors, multiple tumors, patients who cannot tolerate surgery, and patients with cosmetic needs.

[0060] Radiofrequency cutting and radiofrequency ablation each have their own advantages. Doctors can flexibly choose the appropriate treatment method based on the patient's pathological nature, tumor size, patient's physical condition and other factors.

[0061] Based on the same technical concept, the present application also provides a radio frequency operating system, including: a main body, a radio frequency cutting knife connected to the main body, a negative electrode plate, a radio frequency ablation electrode and any radio frequency integrated circuit implemented by the above; the radio frequency cutting knife is used to receive a radio frequency cutting signal to cut biological tissue to obtain a tissue sample while realizing a coagulation function, the radio frequency ablation electrode is connected to the negative electrode plate to form a loop, the radio frequency ablation electrode is used to receive the radio frequency energy signal and the negative electrode plate is used to receive the radio frequency ablation signal, so as to inactivate tumor cells in the target biological tissue.

[0062] The above specific implementations further describe the purpose, technical solutions and beneficial effects of the present application in detail. It should be understood that the above is only a specific implementation of the present application and is not limited to the protection scope of the present application. Without departing from the purpose of the basic characteristics of the present application, the present application can be embodied in various forms. Therefore, the implementation forms in the present application are used for explanation rather than limitation. Since the scope of the present application is limited by the claims rather than the specification, and all changes within the scope defined by the claims or within the equivalent scope of the scope defined by the claims should be understood to be included in the claims. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application should be included in the protection scope of the present application.

Claims

1. A radio frequency integrated circuit, characterized in that: include: Radiofrequency ablation trigger module, radiofrequency cutting trigger module and main control module; The main control module is used to output a first drive signal, a second drive signal and a cutting control signal; The radio frequency ablation trigger module is connected to the main control module, and is used to alternately receive the first drive signal and the second drive signal, and alternately output radio frequency removal signals in sequence; the receiving time of the first drive signal is different from the driving time of the second drive signal, and the radio frequency removal signal includes a radio frequency energy signal and a radio frequency ablation signal, and the radio frequency energy signal and the radio frequency ablation signal are used to inactivate tumor cells in the target biological tissue; The RF cutting trigger module is connected to the main control module, and is used to receive the cutting control signal and output a RF cutting signal, wherein the RF cutting signal includes a positive RF cutting signal and a negative RF cutting signal; the positive RF cutting signal and the negative RF cutting signal are used to achieve coagulation function while cutting biological tissue.

2. The radio frequency integrated circuit according to claim 1, characterized in that: The radiofrequency ablation trigger module comprises: Two signal processing units, the two signal processing units have the same structure, one of the two signal processing units is used to receive the first drive signal and output a first ablation switch control signal, and the other of the two signal processing units is used to receive the second drive signal and output a second ablation switch control signal; A signal generating unit is connected to the signal processing unit, and is used to receive an AC voltage signal, and output the RF energy signal and the RF ablation signal according to the received first ablation switch control signal and the AC voltage signal, or output the RF energy signal and the RF ablation signal according to the received second ablation switch control signal and the AC voltage signal.

3. The radio frequency integrated circuit according to claim 2, characterized in that: One of the signal processing units includes a first driver and a first transistor, and the other of the signal processing units includes a second driver and a second transistor; The input end of the first driver is connected to the first driving signal, the voltage end of the first driver is connected to the first power supply, the ground end of the first driver is grounded, the output end of the first driver is connected to the control electrode of the first transistor, the first electrode of the first transistor is grounded, and the second electrode of the first transistor is used to output the first ablation switch control signal; The input end of the second driver is connected to the second drive signal, the voltage end of the second driver is connected to the first power supply, the ground end of the first driver is grounded, the output end of the second driver is connected to the control electrode of the second transistor, the first electrode of the second transistor is grounded, and the second electrode of the second transistor is used to output the second ablation switch control signal.

4. The radio frequency integrated circuit according to claim 2, characterized in that: The signal generating unit comprises a first transformer, a first multi-stage filter, a first filtering sub-unit and a second filtering sub-unit; The first interface of the first transformer is connected to the first ablation switch control signal, the third interface of the first transformer is connected to the second ablation switch control signal, and the second interface of the first transformer is connected to the AC voltage signal; The fifth interface of the first transformer is connected to the first input end of the first multi-stage filter, and the fourth interface of the first transformer is connected to the second input end of the first multi-stage filter; The first output end of the first multi-stage filter is connected to the first end of the first filter subunit, the second end of the first filter subunit outputs the radio frequency ablation signal, the second output end of the first multi-stage filter is connected to the first end of the second filter subunit, and the second end of the second filter subunit outputs the radio frequency energy signal.

5. The radio frequency integrated circuit according to claim 4, characterized in that: The radiofrequency ablation trigger module also includes: A detection feedback unit, connected to the first multi-stage filter, for sampling and outputting ablation feedback voltage and ablation feedback current to the main control module; The main control module adjusts the magnitude of the AC voltage signal connected to the signal generating unit according to the ablation feedback voltage and the ablation feedback current.

6. The radio frequency integrated circuit according to claim 5, characterized in that: The detection feedback unit includes a second transformer and a third transformer; The fourth interface of the second transformer is connected to the first output end of the first multi-stage filter, and the third interface of the second transformer is connected to the second output end of the first multi-stage filter; The second interface of the second transformer is connected to a voltage sensor to detect and obtain the ablation feedback voltage, and the first interface of the second transformer is connected to a voltage feedback terminal of the main control module to output the ablation feedback voltage to the main control module; The third interface of the third transformer is connected to the fourth interface of the second transformer, and the fourth interface of the third transformer is connected to the first end of the first filtering subunit; The second interface of the third transformer is connected to the current sensor to detect and obtain the ablation feedback current, and the first interface of the third transformer is connected to the current feedback end of the main control module to output the ablation feedback current to the main control module.

7. The radio frequency integrated circuit according to claim 6, characterized in that: The radiofrequency ablation trigger module also includes: The self-check protection unit is connected to the main control module, and is used to detect the circuit according to the self-check trigger signal sent by the main control module, and switch to the protection mode to absorb the counter-attack voltage when the self-check trigger signal is not received.

8. The radio frequency integrated circuit according to claim 7, characterized in that: The self-check protection unit includes a third transistor, a first diode, a first resistor, a second resistor, a third resistor and a relay switch; A first electrode of the third transistor is grounded, a control electrode of the third transistor is connected to a self-test control terminal of the main control module to receive the self-test trigger signal, and a second electrode of the third transistor is connected to an anode of the first diode; An anode of the first diode is connected to a first contact of the relay switch, and a cathode of the first diode is connected to a first power source and a second contact of the relay switch; The third resistor is connected between the third contact of the relay switch and the fourth contact of the relay switch, the second resistor is connected between the first movable contact of the relay switch and the fifth contact of the relay switch, and the first resistor is connected between the sixth contact of the relay switch and the second movable contact of the relay switch; the first movable contact is arranged between the third contact and the fifth contact, and the second movable contact is arranged between the fourth contact and the sixth contact; When the control electrode of the third transistor receives the self-test trigger signal, the second movable contact is connected to the fourth contact, and the first movable contact is connected to the third contact; When the control electrode of the third transistor does not receive the self-test trigger signal, the second movable contact is connected to the sixth contact, and the first movable contact is connected to the fifth contact.

9. The radio frequency integrated circuit according to claim 1, characterized in that: The radio frequency cutting trigger module includes a fourth transistor, a fifth transistor, a fourth transformer, a fifth transformer, a second diode, a choke coil, a second multi-stage filter, a first connector, a second connector and a voltage stabilizer; A first electrode of the fifth transistor is grounded through a resistor and a capacitor, a second electrode of the fifth transistor is connected to a second interface of the fifth transformer, and a control electrode of the fifth transistor is connected to the cutting control signal; The first interface of the fifth transformer is connected to the first power supply, the third interface of the fifth transformer is connected to the power ground, and the fourth interface of the fifth transformer is respectively connected to the cathode of the second diode, one end of the choke coil and the control electrode of the fourth transistor; The other end of the choke coil is connected to the output voltage regulating end of the voltage regulator and the voltage output end of the voltage regulator, and the voltage end of the voltage regulator is connected to the second power supply; The first electrode of the fourth transistor is connected to the second electrode of the fourth transistor, and the second electrode of the fourth transistor is connected to the second interface of the fourth transformer; The first interface of the fourth transformer is connected to the third power supply, the fourth interface of the fourth transformer is connected to the first input end of the second multi-stage filter, the third interface of the fourth transformer is connected to the second input end of the second multi-stage filter, the first output end of the second multi-stage filter is connected to the first connector to output the negative RF cutting signal, and the second output end of the second multi-stage filter is connected to the second connector to output the positive RF cutting signal.

10. A radio frequency operating system, characterized in that: include: A main body, a radio frequency cutting knife connected to the main body, a negative plate, a radio frequency ablation electrode, and a radio frequency integrated circuit according to any one of claims 1 to 9; The radio frequency cutting knife is used to receive a radio frequency cutting signal to cut biological tissue to obtain a tissue sample while realizing a coagulation function. The radio frequency ablation electrode is connected to the negative plate to form a loop. The radio frequency ablation electrode is used to receive the radio frequency energy signal and the negative plate is used to receive the radio frequency ablation signal to inactivate tumor cells in the target biological tissue.

Images