Washing mechanism for reaction cup of chemiluminescence immunity analyzer

Abstract

The invention relates to the technical field of chemiluminescence immunoassay, in particular to a washing mechanism for a reaction cup of a chemiluminescence immunoassay instrument, and solves the problems of complex reaction cup washing operation and low efficiency in the prior art. The invention discloses a washing mechanism for a reaction cup of a chemiluminescence immunoassay analyzer. The washing mechanism comprises an integrated washing assembly, a rotating ring, a bearing cylinder, an elastic tightening rope and the like, the washing assembly is integrated, so that the washing liquid needle, the liquid suction needle and the substrate needle perform cleaning, liquid suction and substrate adding operation on the reaction cup at the same position, the consistency and efficiency of the washing process are improved, and meanwhile, the accuracy and stability of washing and substrate adding are ensured.

Description

Technical Field

[0001] The invention relates to the technical field of chemiluminescent immunoassay, and in particular to a washing mechanism for a reaction cup of a chemiluminescent immunoassay instrument. Background Art

[0002] Chemiluminescent immunoassay analyzer is an immunoassay method that uses chemiluminescent agents to directly label antigens or antibodies. It plays an important role in medical diagnosis, biological research and other fields. The analyzer generates light signals through specific chemical reactions to detect the content of target substances in the sample. When performing analysis, the reaction cup is an indispensable key component as a container for carrying samples and reagents. After the reaction is completed, in order to avoid interference of sample residues on subsequent detection and ensure the accuracy and reliability of the analysis results, the reaction cup must be thoroughly cleaned.

[0003] However, the existing washing mechanism has a low degree of integration. After the washing liquid is filled, the reaction cup needs to be transferred to the position of the liquid aspiration needle to aspirate the liquid. This process not only increases the operation steps, but also slows down the circulation rate of the reaction cup. Afterwards, the reaction cup needs to be transferred to the position of the substrate needle again to add the substrate, which further prolongs the time of the overall cleaning process. Since the washing liquid needle, the liquid aspiration needle and the substrate needle are independent of each other and lack an effective linkage mechanism, the overall washing efficiency cannot be improved.

[0004] This low-integration design not only affects the cleaning efficiency, but also increases the need for manual intervention, as operators need to constantly monitor and adjust the position of the reaction cup. At the same time, due to the discontinuity of the washing process, it is easy to have incomplete cleaning or repeated cleaning, which further reduces the cleaning quality.

[0005] Therefore, in view of the problems of low integration and low cleaning efficiency in the existing chemiluminescence immunoassay reaction cup washing mechanism, we urgently need a chemiluminescence immunoassay reaction cup washing mechanism to solve these problems. This new washing mechanism should be able to significantly improve the integration and efficiency of cleaning, ensure the rapid and efficient cleaning of the reaction cup, simplify the operation process, and provide strong support for the widespread application and efficient operation of chemiluminescence immunoassays. Summary of the invention

[0006] The purpose of the present invention is to provide a washing mechanism for a chemiluminescent immunoassay cuvette to solve the following technical problems: The low-integration design not only affects the cleaning efficiency, but also increases the need for manual intervention, because the operator needs to constantly monitor and adjust the position of the cuvette. At the same time, due to the discontinuity of the washing process, it is easy to cause incomplete cleaning or repeated cleaning, which further reduces the cleaning quality.

[0007] The purpose of the present invention can be achieved through the following technical solutions:

[0008] A washing mechanism for a reaction cup of a chemiluminescent immunoassay analyzer comprises a ring-shaped mounting frame, a rotating ring, a driving component and an integrated washing component;

[0009] The rotating ring is rotatably connected to the top of the annular mounting frame, the driving assembly is installed on one side of the annular mounting frame and is used to drive the rotating ring to rotate, the integrated washing assembly is installed on one side of the inner part of the annular mounting frame, and the integrated washing assembly includes a rotating structure, a lifting structure, a washing liquid needle, a liquid suction needle and a substrate needle;

[0010] The lifting structure is installed on the top of the rotating structure, the washing needles, the aspiration needles and the substrate needles are arranged in an annular array on the periphery of the lifting structure, and a plurality of reaction cups are arranged on the top of the rotating ring, and each of the reaction cups is connected to the top of the rotating ring through a supporting tube.

[0011] As a further solution of the present invention: the rotating structure includes an integrated mounting frame, a rotating plate and a switching motor, the integrated mounting frame is connected to the inner wall of the annular mounting frame, the switching motor is installed at the bottom of the integrated mounting frame and the output shaft passes through the integrated mounting frame and the bottom of the rotating plate through a shaft sleeve for transmission connection.

[0012] As a further solution of the present invention: the lifting structure includes a lifting cylinder and a lifting circular plate, wherein the lifting cylinder is installed on the top of the rotating plate and the output end is connected to the bottom of the lifting circular plate.

[0013] As a further solution of the present invention: the outer ring array of the lifting circular plate has three clamping plates, a movable plate is provided on one side of each clamping plate, a V-shaped groove is opened at the center of the side where the movable plate and the clamping plate are close to each other, and the movable plate and the clamping plate are detachably connected.

[0014] As a further solution of the present invention: a locking screw with one end passing through the movable plate through a threaded sleeve is provided on one side of the movable plate, one end of the locking screw is rotatably connected to the side wall of the clamping plate, a sliding hole is provided on one side of the clamping plate, and a sliding rod with one end connected to the side wall of the movable plate is slidably connected inside the sliding hole, a connecting pipeline is provided at the top center of the lifting circular plate, and independent functional pipelines are provided inside the connecting pipeline, and the washing needle, aspiration needle and substrate needle are respectively connected to the corresponding functional pipelines.

[0015] As a further solution of the present invention: the supporting tube includes a bottom plate and a plurality of fitting protrusions connected to the top edge of the bottom plate and used to surround the reaction cup.

[0016] As a further solution of the present invention: an elastic tightening rope is arranged on the top of the bottom plate, and the elastic tightening rope passes through a plurality of fitting convex pieces respectively, so that the plurality of fitting convex pieces are gathered together.

[0017] As a further solution of the present invention: the outer ring of the rotating ring is sleeved with an outer gear ring, the driving assembly includes a driving motor connected to one side of the annular mounting frame through a side mounting frame, and the output shaft of the driving motor is transmission-connected to an incomplete gear plate meshing with the outer gear ring.

[0018] As a further solution of the present invention: a plurality of guide rods are connected to the top of the rotating plate, and one end of the guide rod passes through the lifting circular plate through a sheath.

[0019] As a further solution of the present invention: the outer ring of the annular mounting frame is connected to a protective outer frame for shielding the outer gear ring and the incomplete gear disk.

[0020] Beneficial effects of the present invention:

[0021] (1) In the present invention, by integrating the design of the washing component, the washing needle, the aspiration needle and the substrate needle are used to clean the reaction cup, aspirate liquid and add substrate at the same position, which significantly improves the consistency and efficiency of the washing process;

[0022] (2) The mechanism rotates the rotating ring and integrates the lifting and lowering of the washing assembly, so that the reaction cup can complete all washing steps without moving, which simplifies the operation process, reduces the need for manual intervention, and reduces the complexity of operation. At the same time, the accuracy and stability of washing and substrate addition are ensured through the controlled rotating structure and lifting structure. In addition, the cooperation of the support cylinder and the elastic tightening rope further enhances the stability of the reaction cup during the washing process and prevents shaking and liquid splashing. The cooperation of the outer gear ring, the incomplete gear plate and the protective outer frame realizes the intermittent rotation of the rotating ring and the effective protection of the transmission components, which improves the reliability and safety of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] The present invention will be further described below in conjunction with the accompanying drawings.

[0024] Figure 1 It is a structural schematic diagram of the annular mounting frame of the present invention;

[0025] Figure 2 It is a schematic structural diagram of the protective outer frame of the present invention;

[0026] Figure 3 It is a schematic diagram of the structure of the side mounting frame and the incomplete gear plate of the present invention;

[0027] Figure 4 It is a schematic diagram of the structure of the rotating ring and the switching motor of the present invention;

[0028] Figure 5 It is a schematic diagram of the structure of the fitting convex piece and the elastic tightening rope of the present invention;

[0029] Figure 6 It is a schematic diagram of the structure of the integrated washing component of the present invention.

[0030] In the figure: 1. integrated washing assembly; 2. annular mounting frame; 3. reaction cup; 4. supporting cylinder; 5. protective outer frame; 6. rotating ring; 7. side mounting frame; 8. incomplete gear plate; 9. driving motor; 10. outer gear ring; 101. switching motor; 102. integrated mounting frame; 103. rotating plate; 104. lifting cylinder; 105. guide rod; 106. locking screw; 107. movable plate; 108. clamping plate; 109. washing liquid needle; 110. aspiration needle; 111. connecting pipeline; 112. lifting circular plate; 113. substrate needle; 401. bottom plate; 402. elastic tightening rope; 403. fitting convex piece. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0032] Embodiment 1

[0033] See also Figure 1-6 As shown, a washing mechanism for a reaction cup of a chemiluminescent immunoassay analyzer of this embodiment includes a ring-shaped mounting frame 2, a rotating ring 6, a driving component and an integrated washing component 1;

[0034] The rotating ring 6 is rotatably connected to the top of the annular mounting frame 2, the driving assembly is installed on one side of the annular mounting frame 2 and is used to drive the rotating ring 6 to rotate, and the integrated washing assembly 1 is installed on one side of the inner part of the annular mounting frame 2. The integrated washing assembly 1 includes a rotating structure, a lifting structure, a washing liquid needle 109, a liquid suction needle 110 and a substrate needle 113;

[0035] The lifting structure is installed on the top of the rotating structure. The washing needle 109, the aspiration needle 110 and the substrate needle 113 are arranged in a circular array on the periphery of the lifting structure. Several reaction cups 3 are arranged on the top of the rotating ring 6. Each reaction cup 3 is connected to the top of the rotating ring 6 through a supporting tube 4.

[0036] Working principle of the present invention: After the chemiluminescent immunoassay analyzer completes the sample detection, samples and reagents will remain in the reaction cup 3, which needs to be cleaned. At this time, the driving component is started to drive the rotating ring 6 to rotate on the annular mounting frame 2. As the rotating ring 6 rotates, each reaction cup 3 passes the position of the integrated washing component 1 in turn. When the reaction cup 3 reaches the washing position, the rotating structure in the integrated washing component 1 starts to work and drives the position of the washing liquid needle 109 to move to the top of the reaction cup 3 for first cleaning, and the lifting structure descends so that the washing liquid needle 109 can penetrate into the interior of the reaction cup 3. First, the washing liquid needle 109 injects an appropriate amount of cleaning liquid into the reaction cup 3 for preliminary cleaning. After the cleaning liquid is injected, the rotating ring 6 continues to rotate, so that the reaction cup 3 is soaked in the cleaning liquid for a period of time to enhance the cleaning effect. Subsequently, when the reaction cup 3 passes the washing position again, the lifting structure drives the liquid aspiration needle 110 to move to the inside of the reaction cup 3 to suck out the residual cleaning liquid and sample residues. Finally, the lifting structure moves again, driving the substrate needle 113 to inject the substrate into the reaction cup 3 to prepare for the next detection. During the whole process, the reaction cup 3 does not need to be moved, and the cleaning and substrate addition can be completed only by the rotation of the rotating ring 6 and the lifting and lowering of the integrated washing component 1, thereby realizing an efficient automated cleaning process.

[0037] The effects that can be achieved by the present invention are as follows: by integrating the design of the washing component 1, the washing needle 109, the liquid aspiration needle 110 and the substrate needle 113 are implemented to clean, aspirate and add substrate to the reaction cup 3 at the same position, avoiding the steps of multiple transfers of the reaction cup in the traditional washing mechanism, and significantly improving the consistency and efficiency of the washing process. At the same time, since the reaction cup 3 does not need to be moved during the entire cleaning process, all operations can be completed only by rotating the rotating ring 6, which not only simplifies the operation process, but also reduces the need for manual intervention and reduces the complexity of the operation. In addition, due to the consistency and efficiency of the washing process, it is ensured that each reaction cup 3 can obtain a consistent cleaning effect, avoiding the problem of incomplete cleaning or repeated cleaning, and improving the cleaning quality. In summary, the washing mechanism of the present invention significantly improves the cleaning efficiency and quality of the reaction cup of the chemiluminescence immunoassay by improving the integration and automation level.

[0038] Embodiment 2

[0039] A washing mechanism for a reaction cup of a chemiluminescent immunoassay analyzer according to this embodiment, such as Figure 1-6As shown, the rotating structure includes an integrated mounting frame 102, a rotating plate 103 and a switching motor 101. The integrated mounting frame 102 is connected to the inner wall of the annular mounting frame 2. The switching motor 101 is installed at the bottom of the integrated mounting frame 102 and the output shaft passes through the integrated mounting frame 102 and is connected to the bottom of the rotating plate 103 through a shaft sleeve. Specifically, through the cooperation of the switching motor 101 and the rotating plate 103, accurate rotation and positioning of the washing component are achieved, so that the washing liquid needle 109, the liquid aspiration needle 110 and the substrate needle 113 can be accurately aligned with the reaction cup 3, ensuring the accuracy and efficiency of the operation.

[0040] Furthermore, the lifting structure includes a lifting cylinder 104 and a lifting circular plate 112. The lifting cylinder 104 is installed on the top of the rotating plate 103 and the output end is connected to the bottom of the lifting circular plate 112. Specifically, through the cooperation of the lifting cylinder 104 and the lifting circular plate 112, the washing needle 109, the aspiration needle 110 and the substrate needle 113 are moved up and down, so that they can penetrate into the reaction cup 3 for cleaning and substrate addition, thereby improving the flexibility and accuracy of the operation.

[0041] Furthermore, the outer ring array of the lifting circular plate 112 has three clamping plates 108, and a movable plate 107 is arranged on one side of each clamping plate 108. A V-shaped groove is opened at the center of the side where the movable plate 107 and the clamping plate 108 are close to each other, and the movable plate 107 and the clamping plate 108 are detachably connected. Specifically, through the cooperation of the clamping plate 108 and the movable plate 107, the washing needle 109, the aspiration needle 110 and the substrate needle 113 are stably fixed, which prevents shaking during operation and ensures the accuracy of cleaning and substrate addition.

[0042] Further, a locking screw 106 having one end passing through the movable plate 107 through a screw sleeve is provided on one side of the movable plate 107, one end of the locking screw 106 is rotatably connected to the side wall of the clamping plate 108, a sliding hole is provided on one side of the clamping plate 108, and a sliding rod having one end connected to the side wall of the movable plate 107 is slidably connected inside the sliding hole, a connecting pipe 111 is provided at the top center of the lifting circular plate 112, and mutually independent functional pipes are provided inside the connecting pipe 111, and the washing needle 109, the liquid aspiration needle 110 and the substrate needle 113 are respectively connected to the corresponding functional pipes, and specifically, through the cooperation of the locking screw 106 and the sliding rod, the clamping plate 108 and the movable plate 107 are tightened and adjusted, ensuring the stable installation of the washing needle 109, the liquid aspiration needle 110 and the substrate needle 113. At the same time, the independent functional pipe design ensures that different liquids do not interfere with each other, and improves the reliability and safety of the operation.

[0043] Embodiment 3

[0044] A washing mechanism for a reaction cup of a chemiluminescent immunoassay analyzer according to this embodiment, such as Figure 1-6 As shown, the supporting tube 4 includes a bottom plate 401 and a plurality of fitting protrusions 403 connected to the top edge of the bottom plate 401 and used to surround the reaction cup 3. Specifically, through the design of the supporting tube 4, especially the surrounding effect of the fitting protrusions 403, the stability of the reaction cup 3 during the rotation process is ensured, and the problem of incomplete cleaning or liquid splashing due to shaking is prevented.

[0045] Furthermore, an elastic tightening rope 402 is provided on the top of the bottom plate 401, and the elastic tightening rope 402 passes through a plurality of fitting protrusions 403 respectively, so that the plurality of fitting protrusions 403 are gathered together. Specifically, through the action of the elastic tightening rope 402, the reaction cup 3 is further fixed and wrapped, the adaptability and stability of the supporting tube 4 are enhanced, and it is ensured that the reaction cups 3 of different sizes and shapes can be well supported and fixed.

[0046] Furthermore, the outer ring of the rotating ring 6 is sleeved with an outer gear ring 10, and the driving assembly includes a driving motor 9 connected to one side of the annular mounting frame 2 through a side mounting frame 7, and the output shaft of the driving motor 9 is transmission-connected to an incomplete gear plate 8 meshing with the outer gear ring 10. Specifically, through the cooperation of the outer gear ring 10 and the incomplete gear plate 8, intermittent rotation of the rotating ring 6 is achieved, so that the reaction cups 3 can pass through the position of the washing assembly one by one for cleaning and substrate addition, thereby improving the washing efficiency and simplifying the operation process.

[0047] Furthermore, a plurality of guide rods 105 are connected to the top of the rotating plate 103, and one end of the guide rod 105 passes through the lifting circular plate 112 through a sheath. Specifically, the design of the guide rod 105 provides a stable guiding effect for the lifting and lowering movement of the lifting circular plate 112, prevents deflection and shaking during the lifting process, and ensures the smoothness and accuracy of the operation.

[0048] Furthermore, the outer ring of the annular mounting frame 2 is connected to a protective outer frame 5 for shielding the outer gear ring 10 and the incomplete gear plate 8. Specifically, through the design of the protective outer frame 5, the transmission components such as the outer gear ring 10 and the incomplete gear plate 8 are effectively shielded and protected, preventing the intrusion of external impurities and liquids, thereby extending the service life of the equipment and improving the safety of operation.

[0049] The above is a detailed description of an embodiment of the present invention, but the content is only a preferred embodiment of the present invention and cannot be considered to limit the scope of implementation of the present invention. All equivalent changes and improvements made within the scope of the present invention should still fall within the scope of the patent coverage of the present invention.

Claims

1. A washing mechanism for a chemiluminescent immunoassay reaction cup, characterized in that: include: An annular mounting frame (2), a rotating ring (6), a driving assembly and an integrated washing assembly (1); The rotating ring (6) is rotatably connected to the top of the annular mounting frame (2); the driving assembly is mounted on one side of the annular mounting frame (2) and is used to drive the rotating ring (6) to rotate; the integrated washing assembly (1) is mounted on one side of the inner portion of the annular mounting frame (2); the integrated washing assembly (1) comprises a rotating structure, a lifting structure, a washing liquid needle (109), a liquid aspiration needle (110) and a substrate needle (113); The lifting structure is installed on the top of the rotating structure. The washing needle (109), the aspiration needle (110) and the substrate needle (113) are arranged in a circular array on the periphery of the lifting structure. A plurality of reaction cups (3) are arranged on the top of the rotating ring (6). Each of the reaction cups (3) is connected to the top of the rotating ring (6) through a supporting tube (4).

2. A washing mechanism for a chemiluminescent immunoassay reaction cup according to claim 1, characterized in that: The rotating structure comprises an integrated mounting frame (102), a rotating plate (103) and a switching motor (101); the integrated mounting frame (102) is connected to the inner wall of the annular mounting frame (2); the switching motor (101) is installed at the bottom of the integrated mounting frame (102) and the output shaft passes through the integrated mounting frame (102) and is transmission-connected to the bottom of the rotating plate (103) through a shaft sleeve.

3. A washing mechanism for a chemiluminescent immunoassay cup according to claim 2, characterized in that: The lifting structure comprises a lifting cylinder (104) and a lifting circular plate (112). The lifting cylinder (104) is installed on the top of the rotating plate (103) and the output end is connected to the bottom of the lifting circular plate (112).

4. A washing mechanism for a chemiluminescent immunoassay reaction cup according to claim 3, characterized in that: The outer ring array of the lifting circular plate (112) has three clamping plates (108), and a movable plate (107) is arranged on one side of each clamping plate (108). A V-shaped groove is provided at the center of the side where the movable plate (107) and the clamping plate (108) are close to each other, and the movable plate (107) and the clamping plate (108) are detachably connected.

5. A washing mechanism for a chemiluminescent immunoassay cup according to claim 4, characterized in that: A locking screw (106) having one end penetrating the movable plate (107) through a threaded sleeve is provided on one side of the movable plate (107); one end of the locking screw (106) is rotatably connected to the side wall of the clamping plate (108); a sliding hole is provided on one side of the clamping plate (108); a sliding rod having one end connected to the side wall of the movable plate (107) is slidably connected inside the sliding hole; a connecting pipeline (111) is provided at the top center of the lifting circular plate (112); independent functional pipelines are provided inside the connecting pipeline (111); the washing needle (109), the aspiration needle (110) and the substrate needle (113) are respectively connected to the corresponding functional pipelines.

6. The washing mechanism for a chemiluminescent immunoassay cuvette according to claim 1, characterized in that: The supporting cylinder (4) comprises a bottom plate (401) and a plurality of fitting protrusions (403) connected to the top edge of the bottom plate (401) and used to surround the reaction cup (3).

7. A washing mechanism for a chemiluminescent immunoassay cup according to claim 6, characterized in that: An elastic tightening rope (402) is arranged on the top of the bottom plate (401), and the elastic tightening rope (402) passes through a plurality of fitting convex pieces (403) respectively, so that the plurality of fitting convex pieces (403) are gathered together.

8. The washing mechanism for a chemiluminescent immunoassay cup according to claim 1, characterized in that: The outer ring of the rotating ring (6) is sleeved with an outer gear ring (10), and the driving assembly includes a driving motor (9) connected to one side of the annular mounting frame (2) through a side mounting frame (7), and the output shaft of the driving motor (9) is drivingly connected to an incomplete gear plate (8) meshing with the outer gear ring (10).

9. The washing mechanism for a chemiluminescent immunoassay cup according to claim 3, characterized in that: A plurality of guide rods (105) are connected to the top of the rotating plate (103), and one end of the guide rod (105) passes through the lifting circular plate (112) through a sheath.

10. The washing mechanism for a chemiluminescent immunoassay cup according to claim 8, characterized in that: The outer ring of the annular mounting frame (2) is connected to a protective outer frame (5) for shielding the outer gear ring (10) and the incomplete gear plate (8).

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