Disintegration experiment device for medicine tablet inspection

By designing a multi-movement disintegration experimental device to simulate stomach dynamics and realize automated cleaning, the problems of inconvenient operation, inaccurate experimental results and cumbersome cleaning in the prior art are solved, and the accuracy and efficiency of the experiment are improved.

CN119881237APending Publication Date: 2025-04-25ANHUI CHENGSHI PHARM CO LTD
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Patent Information

Application Number
CN202510058054.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-14
Publication Date
2025-04-25

AI Technical Summary

Technical Problem

The existing lift disintegrator is inconvenient to operate in disintegration experiments, which easily leads to equipment contamination, and a single movement method is difficult to simulate multiple angles of the stomach. The experimental results are not accurate enough, and the equipment is cumbersome to clean.

Method used

A disintegration experimental device was designed, which simulates the gastric dynamics using multiple movement methods (radial reciprocating, rotation, and circumferential rotation) and realizes automatic cleaning of the equipment through an automated cleaning system.

Benefits of technology

It improves the accuracy of experimental data, simplifies experimental operations, reduces the risk of equipment contamination, and realizes an automated cleaning process, improving experimental efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention provides a disintegration experiment device for medicine tablet inspection, which comprises a water bath box, an experiment barrel is fixedly installed in the water bath box, a central stand column is vertically and fixedly installed at the center of the experiment barrel, and the central stand column is sleeved with a liftable sleeve. A plurality of mounting sleeves are fixedly connected to the circumferential side wall of the bottom of the sleeve through connecting arms, a rotating cylinder is rotationally connected into the mounting sleeves in a penetrating mode, cylindrical net boxes are slidably mounted in the rotating cylinder in the radial direction, and a radial driving mechanism capable of synchronously driving the cylindrical net boxes to do radial reciprocating movement is mounted on the sleeve; a medicine inlet is formed in the top of one end of the cylindrical net box, and the inner side end of the cylindrical net box extends out of the rotary drum to conduct the medicine feeding process. According to the device, the disintegration experiment process can be carried out in various movement modes according to requirements, the dynamic state of the stomach is better simulated, the accuracy of experiment data is improved, and the automatic cleaning process of the device can be achieved.
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Description

Technical Field

[0001] The invention relates to the technical field of medical experimental devices, in particular to a disintegration experimental device for testing drug tablets. Background Art

[0002] Disintegration refers to the complete disintegration or fragmentation of oral solid preparations under specified conditions. Except for insoluble coating materials or broken capsule shells, all should pass through the screen. The disintegration time requirements of different tablets are different. For example, the disintegration time of soluble tablets and dispersible tablets is 3 minutes, and the disintegration time of ordinary tablets is 15 minutes. The disintegration time is determined using a lifting disintegrator.

[0003] At present, the lifting disintegration instrument adopts the form of a hanging basket and a beaker. Multiple tablets can be placed in the hanging basket. The hanging basket needs to be hung on the lifting equipment before disintegration and taken down for observation after disintegration. The up and down operation is inconvenient, the loading process is easily contaminated, and it is difficult to simulate the multi-angle peristalsis of the stomach by relying only on the single lifting movement. The experimental results are not accurate enough. After the experiment, the equipment needs to be manually flushed before the next round of experiments can be carried out, which is more troublesome. Summary of the invention

[0004] In view of the above problems, the present invention provides a disintegration test device for testing drug tablets. The device can adopt a variety of movement modes to perform the disintegration test process according to needs, better simulate the dynamics of the stomach, improve the accuracy of the experimental data, and realize the automatic cleaning process of the equipment.

[0005] To solve the above problems, the technical solution adopted by the present invention is:

[0006] A disintegration test device for testing drug tablets comprises a water bath, wherein an experimental barrel is fixedly installed in the water bath, a central column is vertically fixedly installed at the center of the experimental barrel, a liftable sleeve is mounted on the central column, a bottom circumferential side wall of the sleeve is fixedly connected to a plurality of mounting sleeves through a connecting arm, a rotating drum is rotatably connected to the mounting sleeve, a cylindrical net box is radially slidably installed in the rotating drum, a radial driving mechanism which can synchronously drive a plurality of cylindrical net boxes to move radially back and forth is installed on the sleeve, a medicine inlet is provided at the top of one end of the cylindrical net box, an inner side end of the cylindrical net box extends out of the rotating drum for carrying out a medicine inlet process, the cylindrical net box is located in the rotating drum and carries out a disintegration test through radial reciprocating movement, and an outer side end of the cylindrical net box extends out of the rotating drum for carrying out a rotating disintegration test process, a plurality of flushing pipes for flushing the cylindrical net box are installed on the circumferential side wall of the experimental barrel, and a plurality of drainage ports are circumferentially provided at the bottom of the central column.

[0007] Preferably, a heater is installed at the inner bottom of the water bath, and an annular plate is fixedly connected between the box opening of the water bath and the barrel opening of the experimental barrel.

[0008] Preferably, the central column is hollow, and a partition is fixedly installed inside above the drain port, an electric push rod is fixedly installed on the partition, a lifting block is fixedly connected to the telescopic end of the electric push rod, and the lifting block drives the sleeve to rise and fall.

[0009] Preferably, a motor is installed in the lifting block, and the output end of the motor is fixedly connected to the top of the sleeve.

[0010] Preferably, the radial drive mechanism includes a plurality of electromagnetic blocks circumferentially fixedly installed in the bottom of the sleeve, and the inner end of the cylindrical mesh box is fixedly installed with a magnetic sheet that cooperates with the corresponding electromagnetic block. The magnetic sheet is wrapped by a waterproof membrane, and the electromagnetic block is controlled by a controller to control on and off and power.

[0011] Preferably, a strip groove is provided on the inner top of the rotating drum, a connecting block is elastically connected to the strip groove via a spring, and the connecting block is fixedly connected to the middle part of the cylindrical net box.

[0012] Preferably, a gear is fixedly mounted on the side wall of the rotating drum, a gear ring is fixed on the periphery of the bottom of the central column, and teeth cooperating with the gear are circumferentially arranged on the top of the gear ring.

[0013] Preferably, the inner bottom of the experimental barrel is provided with a connecting port connected to the bottom of the central column, the bottom of the connecting port is connected to a drainage pipe extending from the bottom of the water bath, the bottom pipe mouth of the drainage pipe is threadedly connected to a filter head, a filter screen is installed in the filter head, and a solenoid valve is installed in the connecting port.

[0014] Preferably, the side wall of the water bath is provided with an annular tube, the plurality of flushing tubes are connected to the annular tube, and the annular tube is externally connected to a water pump.

[0015] Preferably, a plurality of magnetic balls are evenly distributed on the inner wall of the cylindrical net box, and an arc-shaped magnet cooperating with the plurality of magnetic balls is embedded in the inner bottom of the rotating drum.

[0016] The beneficial effects of the present invention are:

[0017] 1. By installing the test barrel, the central column, the sleeve, multiple rotating drums, the cylindrical net box and the radial motion mechanism, the test barrel is fixed and does not need to be placed separately for each experiment. Before the experiment, you only need to start the electric push rod to drive the sleeve to rise through the lifting block, so that the multiple rotating drums are raised to the barrel mouth. At this time, the electromagnetic block is in an unpowered state, and the magnetic sheet at the inner end of the cylindrical net box magnetically attracts the unpowered electromagnetic block, so that the inner end extends out of the inner end of the rotating drum. The medicine inlet is in an open state, and tablets can be put into the multiple cylindrical net boxes respectively, and water can be introduced into the test barrel. Or buffer solution, a constant temperature is maintained by a water bath, multiple cylindrical mesh boxes are lowered and immersed in the liquid, the electromagnetic block is controlled to be intermittently turned on and off by a controller, and a magnetic repulsion force is generated between the electromagnetic block and the magnetic sheet when it is energized, and the power of the electromagnetic block is adjusted to the point where the outer end of the cylindrical mesh box does not extend out of the rotating drum, and in conjunction with a spring, the cylindrical mesh box is able to move radially back and forth in the rotating drum. At this time, the drug inlet is located in the rotating drum, and the tablets will not float out, and the degree of disintegration of the tablets can be observed within a unit of time. The experimental operation is simple, and the experimental process is immersed in the liquid, and there will be no splashing of liquid in the lifting experiment.

[0018] 2. By installing a motor, a gear ring, gears and a radial motion mechanism, the dynamics of the stomach can be deeply simulated. Just lower the drum until the gear and the gear ring are meshed, start the motor to drive the sleeve to rotate, and then drive multiple drums to rotate circumferentially through the connecting arm. At the same time, the gear rolls circumferentially on the gear ring to drive the drum to rotate. Then increase the power of the electromagnetic block, that is, increase the current of the electromagnetic block, increase the magnetism, and allow the outer end of the cylindrical net box to intermittently extend out of the outer end of the drum, so as to achieve radial motion, rotation and circumferential rotation, simulate the multi-directional dynamics of the stomach, and improve the accuracy of the experimental data.

[0019] 3. By installing the drain port, drain pipe and filter head, when the experiment is over, the electromagnet is powered off, the drum drives the drug inlet of the cylindrical mesh box to be in a downward state, open the solenoid valve, and discharge the liquid in the experimental barrel. The residual medicine in the cylindrical mesh box enters the drain pipe with the liquid through the drain port, and then is filtered through the filter head. The filter screen filters out the residual medicine. The filter head can be unscrewed to observe, weigh and measure the residual medicine to judge the experimental results.

[0020] 4. By installing multiple flushing pipes, gears, gear rings, drain ports, drain pipes and filter heads, when the experiment is over, the electromagnet is powered off, the drum drives the medicine inlet of the cylindrical net box to be in a downward state, and the water pump pumps water into the multiple flushing pipes, flushing water into the drum from the outside to the inside, flushing the inner wall of the drum, the cylindrical net box and the medicine particles in the experimental barrel, realizing an automatic cleaning process and quickly entering the next experimental process.

[0021] 5. By arranging multiple magnetic balls in the cylindrical mesh box, the multiple magnetic balls are magnetically attracted to the inner wall of the cylindrical mesh box. During the radial reciprocating movement of the cylindrical mesh box, the magnetic balls can intermittently pass through the arc magnet. Under the action of magnetic repulsion, the magnetic balls break away from the inner wall of the cylindrical mesh box and collide or rub against the tablets in the box. The magnetic balls leave the arc magnet and are magnetically attracted to the inner wall again, simulating the process of friction between the tablets and food in the stomach, and fully understanding the tablet disintegration process. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a structural schematic diagram of the present invention;

[0023] Figure 2 for Figure 1 A schematic diagram of the structure enlargement at point A;

[0024] Figure 3 It is a bottom view schematic diagram of multiple states proposed by the present invention;

[0025] Figure 4 It is a schematic diagram of the charging state of the present invention;

[0026] Figure 5 It is a schematic diagram of the radial reciprocating movement experimental state of the present invention;

[0027] Figure 6 It is a schematic diagram of the simulated stomach dynamic experimental state of the present invention;

[0028] Figure 7 This is a structural diagram of embodiment 2 of the present invention.

[0029] In the figure: 1 water bath, 2 annular tube, 3 flushing tube, 4 heater, 5 drain pipe, 6 filter head, 7 filter screen, 8 annular plate, 9 experimental barrel, 10 solenoid valve, 11 drain port, 12 sleeve, 13 lifting block, 14 motor, 15 electric push rod, 16 center column, 17 partition, 18, 19 connecting block, 20 mounting sleeve, 21 connecting arm, 22 gear ring, 23 electromagnetic block, 24 rotating drum, 25 gear, 26 medicine inlet, 27 magnetic sheet, 28 cylindrical net box, 29 magnetic ball, 30 arc magnet. DETAILED DESCRIPTION

[0030] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific implementation disclosed below.

[0031] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "vertical", "horizontal", "left", "right" and similar expressions used herein are for illustrative purposes only and do not represent the only implementation method.

[0032] Embodiment 1

[0033] Reference Figure 1-6 A disintegration test device for testing drug tablets comprises a water bath 1, in which a test barrel 9 is fixedly installed, a central column 16 is vertically fixedly installed at the center of the test barrel 9, a liftable sleeve 12 is mounted on the central column 16, a plurality of mounting sleeves 20 are fixedly connected to the bottom circumferential side wall of the sleeve 12 through a connecting arm 21, a rotating drum 24 is rotatably connected to the mounting sleeve 20, a cylindrical net box 28 is radially slidably installed in the rotating drum 24, a radial driving mechanism which can synchronously drive the plurality of cylindrical net boxes 28 to move radially back and forth is installed on the sleeve 12, a drug inlet 26 is provided at the top of one end of the cylindrical net box 28, an inner side end of the cylindrical net box 28 extends out of the rotating drum 24 for drug inlet process, the cylindrical net box 28 is located in the rotating drum 24 and performs disintegration test by radial reciprocating movement, and an outer side end of the cylindrical net box 28 extends out of the rotating drum 24 for rotary disintegration test process.

[0034] In order to achieve a constant temperature of the water bath 1, a heater 4 is installed at the inner bottom of the water bath 1, and an annular plate 8 is fixedly connected between the box mouth of the water bath 1 and the barrel mouth of the experimental barrel 9. The annular plate 8 can prevent the liquid in the experimental barrel 9 from splashing into the water bath 1 and polluting the water body.

[0035] The central column 16 is hollow inside, and a partition 17 is fixedly installed inside above the drain port 11, an electric push rod 15 is fixedly installed on the partition 17, and a lifting block 13 is fixedly connected to the telescopic end of the electric push rod 15, and the lifting block 13 drives the sleeve 12 to rise and fall.

[0036] In order to realize the circumferential rotation of the multiple rotating drums 24, a motor 14 is installed in the lifting block 13, and the output end of the motor 14 is fixedly connected to the top of the sleeve 12. When the motor 14 is started to drive the sleeve 12 to rotate, the multiple rotating drums 24 can be driven to rotate circumferentially through the connecting arm 21.

[0037] Furthermore, the radial drive mechanism includes a plurality of electromagnetic blocks 23 circumferentially fixedly installed in the bottom of the sleeve 12, and a magnetic sheet 27 cooperating with the corresponding electromagnetic block 23 is fixedly installed on the inner end of the cylindrical mesh box 28, and the magnetic sheet 27 is wrapped by a waterproof membrane. The electromagnetic block 23 is controlled to be on and off and the power by a controller, and a strip groove is provided on the inner top of the rotating drum 24. A connecting block 19 is elastically connected in the strip groove by a spring 18, and the connecting block 19 is fixedly connected to the middle part of the cylindrical mesh box 28. The electromagnetic block 23 is intermittently turned on and off by the controller, and a magnetic repulsion force is generated between the electromagnetic block 23 and the magnetic sheet 27 when it is energized, and the power of the electromagnetic block 23 is adjusted so that the outer end of the cylindrical mesh box 28 does not extend out of the rotating drum 24, and cooperates with the spring 18 to realize the radial reciprocating movement of the cylindrical mesh box 28 in the rotating drum 24.

[0038] Furthermore, a gear 25 is fixedly mounted on the side wall of the rotating drum 24, a gear ring 22 is fixedly mounted on the outer periphery of the bottom of the central column 16, and teeth cooperating with the gear 25 are circumferentially arranged on the top of the gear ring 22. The rotating drum 24 is lowered until the gear 25 is engaged with the gear ring 22, and the motor 14 is started to drive the sleeve 12 to rotate, so that multiple rotating drums 24 can be driven to rotate circumferentially through the connecting arm 21. At the same time, the gear 25 rolls circumferentially on the gear ring 22, driving the rotating drum 24 to rotate.

[0039] The circumferential side walls of the experimental barrel 9 are equipped with multiple flushing pipes 3 for flushing the cylindrical net box 28, and the bottom of the central column 16 is circumferentially provided with multiple drainage ports 11. The inner bottom of the experimental barrel 9 is provided with a connecting port connected to the bottom of the central column 16, and the bottom of the connecting port is connected to a drainage pipe 5 extending from the bottom of the water bath 1. The bottom pipe mouth of the drainage pipe 5 is threadedly connected to a filter head 6, and a filter screen 7 is installed in the filter head 6. A solenoid valve 10 is installed in the connecting port. The electromagnet 23 is powered off, and the rotating drum 24 drives the drug inlet 26 of the cylindrical net box 28 to be in a downward state. The solenoid valve 10 is opened to discharge the liquid in the experimental barrel 9. The residual drug in the cylindrical net box 28 enters the drainage pipe 5 with the liquid through the drainage port 11, and then is filtered through the filter head 6. The filter screen 7 filters out the residual drug. The filter head 6 is unscrewed to observe, weigh and other measurement processes for the residual drug amount to judge the experimental results.

[0040] In addition, the side wall of the water bath 1 is provided with an annular tube 2, and a plurality of flushing tubes 3 are connected to the annular tube 2. The annular tube 2 is externally connected to a water pump, and the water pump pumps water into the plurality of flushing tubes 3, flushing water into the rotating drum 24 from the outside to the inside, flushing the inner wall of the rotating drum 24, the cylindrical mesh box 28 and the medicine particles in the experimental barrel 9, thereby realizing an automatic cleaning process and quickly entering the next experimental process.

[0041] The experimental barrel is fixed and does not need to be placed separately for each experiment. Before the experiment, it is only necessary to start the electric push rod 15 to drive the sleeve 12 to rise through the lifting block 13, so that the multiple rotating drums 24 are raised to the barrel mouth. At this time, the electromagnetic block 23 is in a non-powered state, and the magnetic sheet 27 at the inner end of the cylindrical net box 28 magnetically attracts the non-powered electromagnetic block 23, so that the inner end extends out of the inner end of the rotating drum 24, and the medicine inlet 26 is in an open state, and tablets can be respectively put into the multiple cylindrical net boxes 28, and water or The buffer solution is kept at a constant temperature by a water bath 1, and multiple cylindrical net boxes 28 are lowered and immersed in the liquid. The electromagnetic block 23 is controlled to be intermittently turned on and off by a controller. The electromagnetic block 23 is energized to generate a magnetic repulsion force between the magnetic sheet 27, and the power of the electromagnetic block 23 is adjusted to the outer end of the cylindrical net box 28 does not extend out of the rotating drum 24. In conjunction with the spring 18, the cylindrical net box 28 is radially reciprocating in the rotating drum 24. At this time, the medicine inlet 26 is located in the rotating drum 24, and the tablets will not float out. The degree of tablet disintegration is observed within a unit time.

[0042] The dynamics of the stomach can be deeply simulated. It is only necessary to lower the rotating drum 24 until the gear 25 is meshed with the gear ring 22, and start the motor 14 to drive the sleeve 12 to rotate. The connecting arm 21 can drive multiple rotating drums 24 to rotate circumferentially. At the same time, the gear 25 rolls circumferentially on the gear ring 22 to drive the rotating drum 24 to rotate. Then, the power of the electromagnetic block 23 is increased, that is, the current of the electromagnetic block 23 is increased, and the magnetism is increased, so that the outer end of the cylindrical net box 28 can intermittently extend out of the outer end of the rotating drum 24, thereby realizing radial movement, rotation and circumferential rotation, simulating the multi-directional dynamics of the stomach and improving the accuracy of the experimental data.

[0043] When the experiment is over, the electromagnet 23 is powered off, the drum 24 drives the medicine inlet 26 of the cylindrical net box 28 to be in a downward state, the electromagnetic valve 10 is opened, the liquid in the experimental barrel 9 is discharged, and the residual medicine in the cylindrical net box 28 enters the discharge pipe 5 through the discharge port 11 with the liquid, and then is filtered through the filter head 6. The filter screen 7 filters out the residual medicine. The filter head 6 is unscrewed to observe, weigh and measure the residual medicine amount to judge the experimental results. The water pump pumps water into the multiple flushing pipes 3, flushes water into the drum 24 from the outside to the inside, flushes the inner wall of the drum 24, the cylindrical net box 28 and the medicine particles in the experimental barrel 9, realizes the automatic cleaning process, and quickly enters the next experimental process.

[0044] Embodiment 2

[0045] Reference Figure 7 The difference between this embodiment and the first embodiment is that a plurality of magnetic balls 29 are evenly distributed on the inner wall of the cylindrical net box 28 and an arc magnet 30 cooperating with the plurality of magnetic balls 29 is embedded in the inner bottom of the rotating drum 24 .

[0046] A plurality of magnetic balls 29 are magnetically attracted to the inner wall of the cylindrical mesh box 28. When the cylindrical mesh box 28 is moving radially back and forth, the magnetic balls 29 can intermittently pass through the arc magnet 30. Under the action of the magnetic repulsion force, the magnetic balls 29 break away from the inner wall of the cylindrical mesh box 28 and collide or rub against the tablets in the box. The magnetic balls leave the arc magnet 30 and are magnetically attracted to the inner wall again, simulating the friction between the tablets and the food in the stomach, so as to fully understand the tablet disintegration process.

[0047] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A disintegration test device for testing pharmaceutical tablets, comprising a water bath (1), characterized in that: An experimental barrel (9) is fixedly installed in the water bath (1), a central column (16) is vertically fixedly installed at the center of the experimental barrel (9), a sleeve (12) that can be raised and lowered is mounted on the central column (16), a plurality of mounting sleeves (20) are fixedly connected to the bottom circumferential side wall of the sleeve (12) via a connecting arm (21), a rotating cylinder (24) is rotatably connected to the mounting sleeve (20), a cylindrical net box (28) is radially slidably installed in the rotating cylinder (24), and a cylinder (28) that can synchronously drive the plurality of cylindrical net boxes (28) to move radially back and forth is installed on the sleeve (12). The invention relates to a radial driving mechanism for driving a cylindrical net box (28). A medicine inlet (26) is provided at the top of one end of the cylindrical net box (28). The inner end of the cylindrical net box (28) extends out of the rotating drum (24) to carry out the medicine inlet process. The cylindrical net box (28) is located in the rotating drum (24) and performs a disintegration experiment through radial reciprocating movement. The outer end of the cylindrical net box (28) extends out of the rotating drum (24) to carry out a rotary disintegration experiment process. The circumferential side wall of the experimental barrel (9) is equipped with a plurality of flushing pipes (3) for flushing the cylindrical net box (28). The bottom of the central column (16) is circumferentially provided with a plurality of drainage ports (11).

2. A disintegration test device for testing pharmaceutical tablets according to claim 1, characterized in that: A heater (4) is installed at the inner bottom of the water bath (1), and an annular plate (8) is fixedly connected between the box opening of the water bath (1) and the barrel opening of the experimental barrel (9).

3. A disintegration test device for testing pharmaceutical tablets according to claim 1, characterized in that: The central column (16) is hollow and has a partition (17) fixedly installed above the liquid discharge port (11). An electric push rod (15) is fixedly installed on the partition (17). The telescopic end of the electric push rod (15) is fixedly connected to a lifting block (13). The lifting block (13) drives the sleeve (12) to rise and fall.

4. A disintegration test device for testing pharmaceutical tablets according to claim 3, characterized in that: A motor (14) is installed in the lifting block (13), and an output end of the motor (14) is fixedly connected to the top of the sleeve (12).

5. A disintegration test device for testing pharmaceutical tablets according to claim 1, characterized in that: The radial drive mechanism comprises a plurality of electromagnetic blocks (23) fixedly mounted circumferentially in the bottom of the sleeve (12); a magnetic sheet (27) matching the corresponding electromagnetic block (23) is fixedly mounted on the inner side end of the cylindrical mesh box (28); the magnetic sheet (27) is wrapped by a water-proof membrane; and the on / off and power of the electromagnetic block (23) are controlled by a controller.

6. A disintegration test device for testing pharmaceutical tablets according to claim 1, characterized in that: The inner top of the rotating drum (24) is provided with a strip groove, a connecting block (19) is elastically connected in the strip groove via a spring (18), and the connecting block (19) is fixedly connected to the middle part of the columnar net box (28).

7. A disintegration test device for testing pharmaceutical tablets according to claim 1, characterized in that: A gear (25) is fixedly mounted on the side wall of the rotating drum (24), a gear ring (22) is fixedly mounted on the periphery of the bottom of the central column (16), and teeth cooperating with the gear (25) are circumferentially arranged on the top of the gear ring (22).

8. A disintegration test device for testing pharmaceutical tablets according to claim 1, characterized in that: The inner bottom of the experimental barrel (9) is provided with a connecting port connected to the bottom of the central column (16); the bottom of the connecting port is connected to a drainage pipe (5) extending from the bottom of the water bath (1); the bottom pipe opening of the drainage pipe (5) is threadedly connected to a filter head (6); a filter screen (7) is installed in the filter head (6); and a solenoid valve (10) is installed in the connecting port.

9. A disintegration test device for testing pharmaceutical tablets according to claim 1, characterized in that: The side wall of the water bath (1) is provided with an annular tube (2), a plurality of flushing tubes (3) are connected to the annular tube (2), and the annular tube (2) is externally connected to a water pump.

10. A disintegration test device for testing pharmaceutical tablets according to claim 1, characterized in that: The inner wall of the cylindrical net box (28) is evenly distributed with a plurality of magnetic balls (29) for magnetic attraction, and the inner bottom of the rotating drum (24) is embedded with an arc-shaped magnet (30) that matches the plurality of magnetic balls (29).