Inhalation device and inhalation system for administration by inhalation

Abstract

The present invention relates to medical devices, in particular devices for inhalation of volatile anesthetics. There is provided an inhalation device (1) for administering a medicament by inhalation, the inhalation device (1) comprising a housing (4), a line for delivering an inhalation mixture to a human body, an exhaled gas purification line and a control unit (5), all of which are located within the housing (4). Furthermore, there is provided an inhalation system (3) comprising an inhalation device (1) for administration by inhalation, a delivery device (2) configured to deliver an inhalation mixture from the inhalation device for administration by inhalation to the oral cavity or nasal cavity of a person when the person inhales, a flexible tube (24), and a flexible tube (25) configured to deliver the inhalation mixture from the inhalation device for administration by inhalation to the oral cavity or nasal cavity of the person when the person inhales. And delivering exhaled gas from the oral cavity or nasal cavity of the person back to an inhalation device for administration by inhalation when the person exhales. An inhalation device (1) and an inhalation system (3) for administration of a medicament by inhalation prevent escape of medicament vapour into the environment and ensure delivery of medicament to the human body in a limited, definite dose and controllable manner.

Description

Technical Field

[0001] The present invention relates to medical devices, namely equipment for inhalation of volatile anesthetics. Background Art

[0002] The use of volatile liquids as active substances or volatile liquids containing active substances is well known. One such example is a halogen-containing volatile liquid. Halogen-containing volatile liquids are described as being useful for inducing and / or maintaining anesthesia (including amnesia, muscle paralysis and / or sedation) and / or analgesia, and therefore, they may be useful as volatile anesthetics and / or volatile analgesics.

[0003] The simplest way to induce anesthesia using volatile anesthetics is by inhalation, where a person breathes in vapor or aerosol particles of the volatile anesthetic. A specific feature of anesthesia (analgesia) using volatile anesthetics is the need to control the dose of volatile anesthetic a person inhales, as overdose of volatile anesthetics may result in conditions such as general anesthesia.

[0004] In international application WO 2005 / 118036A2 (published on December 15, 2005), a kind of inhalation system is described, and this system comprises oxygen or air supply source, atomization chamber for medicine, mask and filter.The atomization chamber for medicine is configured to form inhalation mixture by atomizing medicine in oxygen or air, and is configured to have an inlet for oxygen or air supply and an outlet for inhalation mixture.The oxygen or air supply source is connected to the oxygen or air inlet of the medicine atomization chamber by a pipe.The outlet of the inhalation mixture of the atomization chamber for medicine is connected to the mask by a pipe equipped with a one-way valve, and this one-way valve allows the inhalation mixture to flow from the medicine atomization chamber to the mask, and does not allow reverse flow.The filter is configured to purify the medicine in the gas exhaled by people, wherein the filter is configured to have an exhalation gas inlet and a purified air outlet.The exhalation gas inlet of the filter is connected to the mask by a pipe equipped with a one-way valve, and this one-way valve allows the exhalation gas to flow from the mask to the filter, and does not allow reverse flow.

[0005] Known inhalation systems are used as follows: A portion of the medication is poured into the medication atomization chamber. The oxygen or air supply from the oxygen or air source is turned on. Oxygen or air is continuously supplied to the medication atomization chamber where an inhalation mixture is formed. The inhalation mixture from the medication atomization chamber enters the mask. When the patient inhales, the inhalation mixture is inhaled, and then when the patient exhales, the exhaled gas mixes with the portion of the inhalation mixture and enters a filter where the medication is purified.

[0006] In medical technology, the atomization chamber for drugs and other devices required to form the inhalation mixture are usually called inhalation devices. According to the way the inhalation mixture is delivered to the patient's mouth or nose, inhalation devices are divided into active devices, in which the inhalation mixture is delivered by a continuous supply of air or other gases, and passive devices, in which the inhalation mixture is delivered only by the airflow when the patient inhales.

[0007] In the known inhalation system, an active inhalation device is used. The disadvantage of this inhalation device is that the continuous inhalation of the drug, that is, the administration of the drug is unrestricted and uncontrolled, which may lead to drug overdose and induce adverse conditions such as general anesthesia during the inhalation process when using volatile anesthetics (such as methoxyflurane) as drugs for pain relief.

[0008] Another disadvantage of the known inhalation systems is the design of the drug atomization chamber into which the drug must be poured. In the case of using volatile anesthetics as drugs, when pouring the volatile anesthetic, a certain amount of volatile anesthetic vapor enters the air in the room where the patient is located and can be inhaled by other people.

[0009] The technical problem to be solved by the present invention is to develop an improved inhalation device, which is more economical, accurate and safe, and has universality and can be used in conjunction with any delivery device or as a part of an inhalation system.

[0010] Another technical problem of the present invention is to develop an improved inhalation system that is safe, convenient and versatile, and that achieves more economical and accurate control of drug dosage by incorporating an improved inhalation device.

[0011] Another technical problem of the present invention is to expand the range and classification of devices for the inhalation of volatile anesthetics, in particular devices for the inhalation of methoxyflurane, such as inhalation devices used as part of an inhalation system, as well as the inhalation system itself. Summary of the invention

[0012] The first technical problem is solved by a first disclosed content, which is an inhalation device (1) for administering medicine by inhalation, the inhalation device comprising a housing (4), a pipeline for delivering an inhalation mixture to a human body, an exhalation gas purification pipeline, and a control unit (5) located in the housing (4), wherein the pipeline for delivering an inhalation mixture to a human body comprises a nebulizer chamber (6), an inhalation sensor (7), an interface (8) configured to be connected to a bottle containing medicine, and a metering device (9), wherein the exhalation gas purification pipeline comprises a filter (10) configured to purify the medicine in the exhaled gas of a person, wherein the nebulizer chamber (6) comprises a housing (12) and a piezoelectric transducer (13), the piezoelectric transducer (13) being located in the housing (12) of the nebulizer chamber and being configured to form an aerosol of the medicine, wherein the housing (12) of the nebulizer chamber (6) comprises an air supply inlet (14), a medicine supply hole (15) and an inhalation mixture outlet (16), wherein the inhalation sensor (7) The invention comprises an air inlet (17) and an air outlet (18), wherein the interface (8) comprises a drug outlet (19), wherein the doser (9) is configured to deliver the drug from the interface (8) to the piezoelectric transducer (13), and comprises a drug inlet (20) and a drug outlet (21), wherein the filter (10) comprises an inlet (22) for exhaled air to enter, and comprises a purified air outlet (23), wherein the air outlet (18) of the inhalation sensor (7) is connected to the nebulizer chamber (6) The invention relates to a device for injecting a drug into a nebulizer chamber (6) and a housing (12) of the nebulizer chamber (6); wherein the drug outlet (19) of the interface (8) is connected to the drug inlet (20) of the doser (9); wherein the drug outlet (21) of the doser (9) passes through the drug supply hole (15) of the housing (12) of the nebulizer chamber (6); wherein the inhalation sensor (7) is electrically connected to the control unit (5); wherein the piezoelectric transducer (13) is electrically connected to the control unit (5); and wherein the doser (9) is electrically connected to the control unit (5).

[0013] In one aspect of the first disclosure, the atomizing chamber (6) is configured in the following manner, namely, the housing (12) of the atomizing chamber (6) is composed of an upper housing element (29) and a lower housing element (30), and the upper housing element (29) includes a main body part (31) in the form of a hollow cylinder opened from below, having a cylindrical side wall (32) and an upper end wall (33), wherein the upper end wall (33) includes an inhaled mixture outlet (16) in the form of a nozzle, and is composed of a first side part (34) and a second side part (35) connected to the lower part of the cylindrical side wall (32) so that they are located on opposite sides of the cylindrical side wall (32), wherein the first side part (34) includes an air supply inlet (14) in the form of a nozzle, and the second side part (35) includes a deepening part (36), and air flows from the internal space of the lower housing element (30) through the internal space of the deepening part (36) to the internal space of the main body part (31). The upper part of the second side portion (35) includes a drug supply hole (15), the lower shell element (30) includes a longitudinal deepening portion (37), and air flows from the air supply inlet (14) to the internal space of the deepening portion (36) through the internal space of the longitudinal deepening portion, wherein the atomization chamber (6) further includes a partition (38) located between the upper shell element (29) and the lower shell element (30), the partition (38) separates the internal space of the longitudinal deepening portion (37) from the internal space of the main body portion (31), the portion of the partition (38) located below the air supply inlet (14) is provided with one or more holes (55), and air flows from the air supply inlet (14) to the internal space of the longitudinal deepening portion (37) through the one or more holes, and the portion of the partition (38) located below the drug supply hole (15) includes a hole (56), and the piezoelectric transducer (13) is located above or below the hole (56).

[0014] In one aspect of the first disclosure, the atomization chamber (6) further includes an air inlet valve (57), which is configured to introduce air into the atomization chamber (6) through the air supply inlet (14) and prevent air from escaping from the atomization chamber (6) through the air supply inlet (14), and the air inlet valve (57) is located at the air supply inlet (14) of the housing (12) of the atomization chamber (6) or near the air supply inlet (14).

[0015] In one aspect of the first disclosure, the interface (8) may further include a first needle (39) configured to have a through channel for piercing a stopper on a bottle containing a drug and delivering the drug from the bottle containing the drug to a drug outlet (19) of the interface (8).

[0016] In one aspect of the first disclosure, the interface (8) may further include an air inlet (40), a second needle (41), and the second needle (41) is configured to have a through channel for piercing a stopper on a bottle containing a drug and delivering air from the air inlet (40) to the bottle containing the drug.

[0017] In one aspect of the first disclosure, the inhalation sensor (7) is configured to provide a signal to the control unit (5) when a person inhales, and the control unit (5) is configured to power the metering device (9) only when a signal is received from the inhalation sensor (7) during the person's inhalation, so that the metering device (9) delivers a dose of the drug to the nebulization chamber (6).

[0018] In one aspect of the first disclosure, a pipeline for delivering an inhaled mixture to a human body may include an element (11) for forming an airflow, which is configured to force an airflow in the inhaled mixture pipeline and / or the exhaled gas purification pipeline, and is configured to include an air inlet (42) and an air outlet (43), wherein the element (11) for forming an airflow is electrically connected to a control unit (5), and the air outlet (43) of the element (11) for forming an airflow is connected to an air inlet (17) of an inhalation sensor (7).

[0019] In one aspect of the first disclosure, an inhalation mixture forming pipeline for administration to a person may include an element (11) for forming an airflow, which is configured to force an airflow in the inhalation mixture forming pipeline and / or the exhalation gas purification pipeline, and is configured to include an air inlet (42) and an air outlet (43), and the element (11) for forming an airflow is electrically connected to a control unit (5), the air inlet (42) of the element (11) for forming an airflow is connected to an air outlet (18) of an inhalation sensor (7), and the air outlet (43) of the element (11) for forming an airflow is connected to an air supply inlet (14) of a housing (12) of a nebulization chamber (6).

[0020] In one aspect of the first disclosure, the exhaled gas purification line may include an element (11) for forming an airflow, which is configured to force an airflow in the inhaled mixture line and / or the exhaled gas purification line, and is configured to include an air inlet (42) and an air outlet (43), wherein the element (11) for forming an airflow is electrically connected to the control unit (5), and the air inlet (42) of the element (11) for forming an airflow is connected to the purified air outlet (23) of the filter (10).

[0021] In one aspect of the first disclosure, a fan is used as the element (11) for forming the airflow.

[0022] In one aspect of the first disclosure, the inhalation device (1) for administering a drug by inhalation may further comprise at least one heating element, wherein the at least one heating element is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

[0023] In one aspect of the first disclosure, the atomization chamber (6) may further include at least one heating element, which is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

[0024] In one aspect of the first disclosure, the atomization chamber (6) may further include at least one heating element, which is configured to heat the air or the inhaled mixture in the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

[0025] In one aspect of the first disclosure, the drug is methoxyflurane.

[0026] The second technical problem is solved by the second disclosed content, which is an inhalation system (3), which includes an inhalation device (1) for administering drugs by inhalation, a delivery device (2), a flexible tube (24) and a flexible tube (25), wherein the delivery device (2) is configured to deliver an inhalation mixture from the inhalation device (1) for administering drugs by inhalation to the oral cavity or nasal cavity of the person when the person inhales, and to deliver exhaled gas from the oral cavity or nasal cavity of the person back to the inhalation device (1) for administering drugs by inhalation when the person exhales, wherein the inhalation device (1) for administering drugs by inhalation includes a housing (4), a pipeline for delivering the inhalation mixture to the human body, an exhaled gas purification pipeline, and a control unit (5) located in the housing (4), wherein A pipeline for delivering an inhaled mixture to a human body comprises a nebulizer chamber (6), an inhalation sensor (7), an interface (8) configured to be connected to a bottle containing a drug, and a metering device (9), wherein the exhaled gas purification pipeline comprises a filter (10) configured to purify the drug in the exhaled gas of a person, wherein the nebulizer chamber (6) comprises a housing (12) and a piezoelectric transducer (13), the piezoelectric transducer (13) being located in the housing (12) of the nebulizer chamber and configured to form an aerosol of the drug, wherein the housing (12) of the nebulizer chamber (6) comprises an air supply inlet (14), a drug supply hole (15) and an inhaled mixture outlet (16), wherein the inhalation sensor (7) comprises an air inlet (17) and an air outlet (18), wherein the interface (9) comprises an air supply inlet (18) and an air outlet (19), wherein the (8) includes a drug outlet (19), wherein the dosing device (9) is configured to deliver the drug from the interface (8) to the piezoelectric transducer (13), and includes a drug inlet (20) and a drug outlet (21), wherein the filter (10) includes an inlet (22) through which exhaled air enters, and includes a purified air outlet (23), wherein the air outlet (18) of the inhalation sensor (7) is connected to the air supply inlet (14) of the housing (12) of the nebulization chamber (6), wherein the drug outlet (19) of the interface (8) is connected to the drug inlet (20) of the dosing device (9), wherein the drug outlet (21) of the dosing device (9) passes through the drug supply hole (15) of the housing (12) of the nebulization chamber (6), and wherein the inhalation sensor (7) is connected to the drug supply hole (15) of the housing (12) of the nebulization chamber (6). The device (7) is electrically connected to the control unit (5), the piezoelectric transducer (13) is electrically connected to the control unit (5), and the dosing device (9) is electrically connected to the control unit (5), wherein the delivery device (2) comprises an inhaled mixture inlet (26), an exhaled gas outlet (27) and a breathing inlet (28), when a human body inhales, the inhaled mixture is delivered to the human oral cavity or nasal cavity through the breathing inlet, and when a human body exhales, the exhaled gas is discharged from the human oral cavity or nasal cavity through the breathing inlet, wherein a first end of the flexible tube (24) is connected to the inhaled mixture outlet (16) of the housing (12) of the atomization chamber (6), and a second end of the flexible tube (24) is connected to the inhaled mixture inlet (26) of the delivery device (2), wherein,A first end of the flexible tube (25) is connected to the inlet (22) of the filter (10), and a second end of the flexible tube (25) is connected to the exhaled gas outlet (27) of the delivery device (2).

[0027] In one aspect of the second disclosure, the atomizing chamber (6) is configured in the following manner, namely, the housing (12) of the atomizing chamber (6) is composed of an upper housing element (29) and a lower housing element (30), and the upper housing element (29) includes a main body part (31) in the form of a hollow cylinder opened from below, having a cylindrical side wall (32) and an upper end wall (33), wherein the upper end wall (34) includes an inhaled mixture outlet (16) in the form of a nozzle, and is composed of a first side part (34) and a second side part (35) connected to the lower part of the cylindrical side wall (32) so that they are located on opposite sides of the cylindrical side wall (32), wherein the first side part (34) includes an air supply inlet (14) in the form of a nozzle, and the second side part (35) includes a deepening part (36), and air flows from the internal space of the lower housing element (30) through the internal space of the deepening part (36) to the internal space of the main body part (31). The upper part of the second side portion (35) includes a drug supply hole (15), the lower shell element (30) includes a longitudinal deepening portion (37), and air flows from the air supply inlet (14) to the internal space of the deepening portion (36) through the internal space of the longitudinal deepening portion, wherein the atomization chamber (6) further includes a partition (38) located between the upper shell element (29) and the lower shell element (30), the partition (38) separates the internal space of the longitudinal deepening portion (37) from the internal space of the main body portion (31), the portion of the partition (38) located below the air supply inlet (14) is provided with one or more holes (55), and air flows from the air supply inlet (14) to the internal space of the longitudinal deepening portion (37) through the one or more holes, and the portion of the partition (38) located below the drug supply hole (15) includes a hole (56), and the piezoelectric transducer (13) is located above or below the hole (56).

[0028] In one aspect of the second disclosure, the atomization chamber (6) may include an air inlet valve (57), which is configured to introduce air into the atomization chamber (6) through the air supply inlet (14) and prevent air from escaping from the atomization chamber (6) through the air supply inlet (14), and the air inlet valve (57) is located at the air supply inlet (14) of the housing (12) of the atomization chamber (6) or near the air supply inlet (14).

[0029] In one aspect of the second disclosure, the delivery device (2) may include an inhalation channel for delivering an inhalation mixture to a human body, an inhalation mixture inlet (26) connected to a first end of the inhalation channel, an exhalation channel for discharging exhaled gas, an exhalation gas outlet (27) connected to the first end of the exhalation channel, an exhalation valve located in the inhalation channel and opened only during human inhalation, an exhalation valve located in the exhalation channel and opened only during human exhalation, and a breathing chamber, wherein the breathing chamber is configured to deliver the inhalation mixture from the inhalation channel to the human oral cavity or nasal cavity when the human body inhales, and to discharge the exhaled gas from the human oral cavity or nasal cavity to the exhalation channel when the human body exhales, wherein the breathing chamber includes a first inlet connected to a second end of the inhalation channel, a second inlet connected to a second end of the exhalation channel, and a breathing inlet (28), during human inhalation, the inhalation mixture is delivered to the human oral cavity or nasal cavity through the breathing inlet (28), and during human exhalation, the exhaled gas is discharged from the human oral cavity or nasal cavity.

[0030] In one aspect of the second disclosure, the delivery device (2) may include a housing (44), a channel element (47) located in the housing (44), and a breathing chamber (48) located in the housing (44), wherein the housing (44) includes a first housing element (45) and a second housing element (46), the channel element (47) includes a tubular inhalation channel (49), a tubular exhalation channel (50), an inhalation mixture inlet (26) configured in the form of a nozzle and connected to a first end of the inhalation channel (49), an exhalation gas outlet (27) configured in the form of a nozzle and connected to the exhalation gas outlet (50). The breathing chamber (48) comprises a first end of a channel (50), an inhalation valve (51) located in the inhalation channel (49) and opened only when a person inhales, and an exhalation valve (52) located in the exhalation channel (50) and opened only when a person exhales. The breathing chamber (48) comprises a first inlet (53) connected to the second end of the inhalation channel (49), a second inlet (54) connected to the second end of the exhalation channel (50), and a breathing inlet (28), through which the inhaled mixture is delivered to the oral cavity or nasal cavity of the person when the person inhales, and the exhaled gas is discharged from the oral cavity or nasal cavity of the person when the person exhales.

[0031] In one aspect of the second disclosure, the interface (8) may further include a first needle (39) configured to have a through channel for piercing a stopper on a bottle containing a drug and delivering the drug from the bottle containing the drug to the drug outlet (19) of the interface (8).

[0032] In one aspect of the second disclosure, the interface (8) may further include an air inlet (40), a second needle (41), and the second needle (41) is configured to have a through channel for piercing a stopper on a bottle containing a drug and delivering air from the air inlet (40) to the bottle containing the drug.

[0033] In one aspect of the second disclosure, the inhalation sensor (7) is configured to provide a signal to the control unit (5) when a person inhales, and the control unit (5) is configured to power the metering device (9) only when a signal is received from the inhalation sensor (7) during the person's inhalation, so that the metering device (9) delivers a dose of the drug to the nebulization chamber (6).

[0034] In one aspect of the second disclosure, the inhalation system (3) may further include a plug configured to close a breathing inlet (28) of the delivery device (2), and the pipeline for delivering an inhaled mixture to a human body may further include an element for forming an airflow (11), which is configured to force an airflow in the pipeline for delivering an inhaled mixture to a human body and / or the exhaled gas purification pipeline, and is configured to include an air inlet (42) and an air outlet (43), wherein the element for forming an airflow (11) is electrically connected to the control unit (5), and the air outlet (43) of the element for forming an airflow (11) is connected to the air inlet (17) of the inhalation sensor (7).

[0035] In one aspect of the second disclosure, the inhalation system (3) may further include a plug configured to close the respiratory inlet (28) of the delivery device (2), and the pipeline for delivering the inhaled mixture to the human body may further include an element (11) for forming an airflow, which is configured to force an airflow in the inhaled mixture pipeline and / or the exhaled gas purification pipeline, and is configured to include an air inlet (42) and an air outlet (43), wherein the element (11) for forming an airflow is electrically connected to the control unit (5), the air inlet (42) of the element (11) for forming an airflow is connected to the air outlet (18) of the inhalation sensor (7), and the air outlet (43) of the element (11) for forming an airflow is connected to the air supply inlet (14) of the housing (12) of the atomization chamber (6).

[0036] In one aspect of the second disclosure, the inhalation system (3) may further include a plug configured to close the breathing inlet (28) of the delivery device (2), and the exhaled gas purification line may further include an element (11) for forming an airflow, which is configured to force an airflow in the inhaled mixture line and / or the exhaled gas purification line, and is configured to include an air inlet (42) and an air outlet (43), wherein the element (11) for forming an airflow is electrically connected to the control unit (5), and the air inlet (42) of the element (11) for forming an airflow is connected to the purified air outlet (23) of the filter (10).

[0037] In one aspect of the second disclosure, a fan is used as the element (11) for forming the airflow.

[0038] In one aspect of the second disclosure, the inhalation device (1) for administering a drug by inhalation may further comprise at least one heating element, wherein the at least one heating element is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

[0039] In one aspect of the second disclosure, the atomization chamber (6) may further include at least one heating element, which is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

[0040] In one aspect of the second disclosure, the atomization chamber (6) may further include at least one heating element, which is configured to heat the air or inhaled mixture in the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

[0041] In one aspect of the second disclosure, the flexible tube (24) may include at least one heating element configured to heat the flexible tube (24) or heat the inhaled mixture passing through the flexible tube (24) and configured to be electrically connected to the control unit (5).

[0042] In one aspect of the second disclosure, the flexible tube (25) may include at least one heating element, which is configured to heat the flexible tube (25) or heat the exhaled gas passing through the flexible tube (25) and is configured to be electrically connected to the control unit (5).

[0043] In one aspect of the second disclosure, the inhalation system (3) may include a mouthpiece, a mouthpiece, or a mask, each configured to be connected to the respiratory inlet (28) of the delivery device (2).

[0044] In one aspect of the second disclosure, the drug is methoxyflurane. BRIEF DESCRIPTION OF THE DRAWINGS

[0045] In the following, in order to better understand the essence of the present invention, Figure 1-20 The drawings in the drawings show possible examples of embodiments of the claimed disclosure.

[0046] Figure 1 is an overall view of an inhalation device (1) for administering medication by inhalation.

[0047] Figure 2 is an overall view of the suction system (3).

[0048] Figure 3 The invention discloses an overall view of a suction system (3) having a conveying device (2), wherein a suction nozzle is mounted on the conveying device (2).

[0049] Figure 4 It is an overall view of the atomization chamber (6) and the metering device (9).

[0050] Figure 5 It is a view of the disassembled atomization chamber (6) and the metering device (9) according to one aspect.

[0051] Figure 6 It is a view of the disassembled atomization chamber (6) and the metering device (9) according to one aspect.

[0052] Figure 7 It is a front cross-sectional view of the atomizing chamber (6) and the dosing device (9).

[0053] Figure 8 is a schematic diagram of the air flow in the atomization chamber (6).

[0054] Fig. 9 It is an overall view of the conveying device (2) together with the flexible tube (24) and the flexible tube (25).

[0055] Fig.10 It is a side view of the conveying device (2) with the flexible tube (24) and the flexible tube (25).

[0056] Fig.11 is a view of a disassembled conveying device (2).

[0057] Fig.12 yes Fig.12 AA section in.

[0058] Fig.13 It is an overall view of the interface (8) with the protective cover of the bottle containing the drug.

[0059] Fig.14 It is a front cross-sectional view of the interface (8) of a bottle containing medicine.

[0060] Fig.15 It is a front cross-sectional view of the interface (8) located in the housing (4), wherein the bottle is filled with medicine.

[0061] Fig.16 is a schematic diagram of an inhalation device (1) for administering a drug by inhalation according to one aspect.

[0062] Fig.17 is a schematic diagram of the suction system (3).

[0063] Fig.18 is a schematic diagram of an inhalation device (1) for administering a drug by inhalation according to one aspect.

[0064] Fig.19is a schematic diagram of an inhalation device (1) for administering a drug by inhalation according to one aspect.

[0065] Fig. 20 is a schematic diagram of an inhalation device (1) for administering a drug by inhalation according to one aspect. DETAILED DESCRIPTION

[0066] The first disclosure is an inhalation device (1) for administering medication by inhalation.

[0067] Figure 1 , Figure 4-8 , Figure 13-16 and Figure 18-20 Different embodiments of an inhalation device (1) for administering a drug by inhalation and structural elements of an inhalation device (1) for administering a drug by inhalation are shown.

[0068] The second disclosure is an inhalation system (3).

[0069] Figure 2 , Figure 3 , Figure 9-12 and Fig.17 Different embodiments of an inhalation system (3) and structural elements of an inhalation system (3) are shown.

[0070] Since the basic element of the inhalation system (3) is the inhalation device (1) for administering drugs by inhalation, which ensures the functionality of the inhalation system (2), it is obvious that various embodiments of the inhalation device (1) for administering drugs by inhalation lead to different configurations of the inhalation system (3).

[0071] An inhalation device (1) for administering medication by inhalation according to a main embodiment of the first disclosure (general view as shown in FIG. Figure 1 As shown in the schematic diagram Fig.16 ) comprises a housing (4), a pipeline for delivering an inhaled mixture to a human body, an exhaled gas purification pipeline and a control unit (5), all of which are located within the housing (4).

[0072] The exhaled air purification line includes a filter (10) configured to purify drugs in human exhaled air, wherein the filter (10) includes an inlet (22) through which the exhaled air enters and a purified air outlet (23). The filter (10) includes a filter material that absorbs drugs from human exhaled air. For example, the filter (10) may include activated carbon, a filter element with activated carbon (e.g., a Delta Plus filter element with activated carbon) as the filter material.

[0073] The pipeline for delivering an inhalation mixture to a human body is composed of structural elements, such as a nebulizer chamber (6), an inhalation sensor (7), an interface (8) configured to connect a bottle containing a drug, and a metering device (9) for delivering the drug from the interface (8) to the nebulizer chamber (6).

[0074] The atomizing chamber (6) comprises a housing (12) and a piezoelectric transducer (13) located in the housing (12) of the atomizing chamber. The housing (12) of the atomizing chamber (6) comprises an air supply inlet (14), a drug supply hole (15) and an inhaled mixture outlet (16).

[0075] Air enters the inner space of the nebulizer chamber (6) through the air supply inlet (14). Drugs enter the inner space of the nebulizer chamber (6) through the drug supply hole (15). An inhalation mixture formed by the aerosol mixture of air and drug leaves the nebulizer chamber (6) through the inhalation mixture outlet (16).

[0076] The piezoelectric transducer (13) is configured to convert a liquid drug into an aerosol. The piezoelectric transducer (13) is any device that converts alternating current into high frequency oscillations, which, when a liquid comes into contact with the device, form aerosol particles of the liquid. An example of a piezoelectric transducer (13) that can be used in the first disclosure is an ultrasonic membrane commonly used in state-of-the-art inhalation devices. The piezoelectric transducer (13) is electrically connected to a control unit (5): the control unit (5) supplies alternating current to the piezoelectric transducer (13).

[0077] The interface (8) is configured to connect to a bottle containing a drug and to deliver the drug from the bottle containing the drug to the inhalation system (3). The interface (8) is configured to have a drug outlet (19). Any object and / or device suitable for connecting to a bottle and having an outlet for delivering liquid from the bottle can be used as the interface (8).

[0078] The doser (9) is configured to deliver the drug from the interface (8) to the piezoelectric transducer (13) of the atomization chamber (6). The doser (9) includes a drug inlet (20) and a drug outlet (21). The drug inlet (20) of the doser (9) is connected to the drug outlet (19) of the interface (8), and the drug outlet (21) of the doser (7) passes through the drug supply hole (15) of the housing (12) of the atomization chamber (6), so that the drug can reach the piezoelectric transducer (13) through the drug outlet (21). In the following, when it is described that one structural element is connected to another structural element, it should be understood that such connection can be direct or through an intermediate element (e.g., a pipeline), and a medium such as air or drug passes through the pipeline.

[0079] Any object, device and / or system capable of supplying a liquid can be used as the dosing device (9). For example, it can be an electromagnetic pump, which is commonly used in inhalation devices and similar devices. The drug outlet (21) refers to any pipe connected to the dosing device (9) through which the drug can leave the dosing device (8). The dosing device (9) has an electrical connection to the control unit (5): the control unit (5) provides the dosing device (9) with the power required for the normal operation of the dosing device (9).

[0080] The inhalation sensor (7) comprises an air inlet (17) and an air outlet (18). The air outlet (18) of the inhalation sensor (7) is connected to the air supply inlet (14) of the housing (12) of the nebulization chamber (6). Any sensor that emits a signal when an air flow passes through can be used as an inhalation sensor. In this case, when a person inhales, an air flow is formed in the sensor. This is why this structural element is called an inhalation sensor. The inhalation sensor (7) is electrically connected to the control unit (5): the control unit (5) receives the signal emitted by the inhalation sensor (7) during the person's inhalation and, based on the signal from the inhalation sensor (7), performs specific control of the drug delivery to the nebulization chamber (6).

[0081] In a preferred embodiment of the first disclosure, the control unit (5) is configured to supply power to the metering device (9) so that the metering device (9) delivers a specific predetermined dose of the drug to the nebulizer chamber (6) only when it receives a signal from the inhalation sensor (7) during the person's inhalation. Due to this configuration of the inhalation sensor (7) and the control unit (5), and the regulation of the drug dose delivered during each administration of the drug to the nebulizer chamber (6), the formation of the inhalation mixture inhaled by the person is performed only during the person's inhalation, and at the same time, the amount of drug administered to the person is limited and controlled. Accordingly, this operating mode of the inhalation device (1) for administering drugs by inhalation enables clear and controlled administration of drugs to the human body, which can prevent an overdose of volatile anesthetics and the occurrence of general anesthesia during the inhalation process when using drugs such as volatile anesthetics.

[0082] The dose of drug delivered to the piezoelectric transducer (13) of the nebulization chamber (6) can be adjusted in various ways, for example, by adjusting the volume flow rate of the metering device (9) (for example, mechanical adjustment of the metering device (9)), and by using a control unit (5) to change the working time of the metering device (9) during the person's inhalation (for example, so that the drug is always supplied by the metering device (9) from the beginning of the person's inhalation, or is only administered within the first 1-2 seconds after the beginning of the person's inhalation).

[0083] The inhalation system (3) according to the main embodiment of the second disclosure (overall view as shown in FIG. Figure 1 , Figure 2 As shown in the schematic diagram Fig.17The invention discloses an inhalation device (1) for administering drugs by inhalation according to the main embodiment of the first disclosure described above, and comprises a delivery device (2), a flexible tube (24) and a flexible tube (25), wherein the delivery device (2) is configured to deliver the inhaled mixture from the inhalation device (1) for administering drugs by inhalation to the oral cavity or nasal cavity of the person when the person inhales, and to deliver the exhaled gas from the oral cavity or nasal cavity of the person back to the inhalation device (1) for administering drugs by inhalation when the person exhales.

[0084] Conveying device (2) (such as Fig. 9 The inhaled mixture is transported to the oral cavity or nasal cavity of the person through the respiratory inlet (28) during the person's inhalation, and is discharged from the oral cavity or nasal cavity of the person through the respiratory inlet (28) during the person's exhalation.

[0085] The flexible tube (24) is configured to supply an inhalation mixture from the atomizing chamber (6) to the delivery device (2). A first end of the flexible tube (24) is connected to an inhalation mixture outlet (16) of a housing (12) of the atomizing chamber (6), and a second end of the flexible tube (24) is connected to an inhalation mixture inlet (26) of the delivery device (2).

[0086] The flexible tube (25) is configured to transport human exhaled gas from the delivery device (2) to the filter (10). The first end of the flexible tube (25) is connected to the inlet (22) of the filter (10), and the second end of the flexible tube (24) is connected to the exhaled gas outlet (27) of the delivery device (2).

[0087] A mouthpiece, mouthpiece or mask may be attached to the respiratory inlet (28) of the delivery device (2) to provide inhalation.

[0088] Hereinafter, an example using the inhalation system (3) according to the main embodiment of the second disclosure is described.

[0089] The bottle containing the drug is inserted into the interface (8). The mouthpiece is attached to the breathing inlet (28) of the delivery device (2). The control unit (5) is switched on and the control unit (5) supplies an alternating current to the piezoelectric transducer (13). The person inserts the mouthpiece into the mouth and inhales.

[0090] When a person inhales, an air flow is formed in the atomizing chamber (6) and the inhalation sensor (7), and the air enters the inner space of the housing (12) of the atomizing chamber (6) through the air outlet (18) of the inhalation sensor (6) and the air supply inlet (14) of the housing (12) of the atomizing chamber (6). At the same time, the inhalation sensor (7) generates a signal that enters the control unit (5). The control unit (5) supplies power to the metering device (9), and the metering device (9) starts to supply medicine from the interface (8) to the piezoelectric transducer (13). After the medicine reaches the piezoelectric transducer (13), it is atomized into an aerosol form and continuously mixed with the air flow passing through the inner space of the atomizing chamber (6) to form an inhalation mixture. The inhalation mixture enters the conveying device (2) through the inhalation mixture outlet (16) in the housing (12) of the atomizing chamber (6), the flexible tube (24) and the inhalation mixture inlet (26) of the conveying device (2). The inhaled mixture enters the oral cavity of a person from the delivery device (2) through the breathing inlet (28) of the delivery device (2) and the mouthpiece.

[0091] During the exhalation of the person, after the person inhales, the air flow through the inhalation sensor (7) stops, the signal received by the control unit (5) disappears, and the control unit (5) stops supplying power to the metering device (9), so that the metering device (9) stops supplying the drug from the interface (8) to the piezoelectric transducer (13). At the same time, the gas exhaled by the person through the mouthpiece and the breathing inlet (28) of the delivery device (2) enters the delivery device (2). The exhaled gas enters the filter (10) from the delivery device (2) through the exhaled gas outlet (27) of the delivery device (2), the flexible tube (25) and the inlet (22) of the filter (10). When the person exhales, the exhaled gas passes through the filter (10), where the drug is purified, and the purified air leaves the filter (10) through the purified air outlet (23) and is discharged into the environment.

[0092] In subsequent inhalation-exhalation cycles of the person, the function of the inhalation system (3) is repeated as described above.

[0093] According to one of the embodiments of the first disclosure and the second disclosure, in order to ensure a one-way flow of the inhaled mixture when a person inhales and a one-way flow of the exhaled gas when a person exhales, the atomizing chamber (6) may include an air inlet valve (57), which is configured to introduce air into the atomizing chamber (6) through the air supply inlet (14) and prevent the air from leaving the atomizing chamber (6) through the air supply inlet (14), and the air inlet valve (57) is located at or near the air supply inlet (14) of the housing (12) of the atomizing chamber (6). The presence of the air inlet valve in the housing (12) of the atomizing chamber (6) allows air to enter the internal space of the housing (12) of the atomizing chamber (6) through the air supply inlet (14) only during a person's inhalation. Therefore, when a person inhales, the inhaled mixture flows from the atomizing chamber (6) to the delivery device (2), and when a person exhales, the inhaled mixture cannot move from the delivery device (2) to the atomizing chamber (6).

[0094] According to another embodiment of the second disclosure, in order to fully ensure the unidirectional flow of the inhaled mixture when a person inhales and the unidirectional flow of the exhaled gas when a person exhales, the delivery device (2) may include: an inhalation channel through which the inhaled mixture is delivered to a person, an inhaled mixture inlet (26) connected to a first end of the inhalation channel, an exhalation channel for discharging the exhaled gas, an exhalation gas outlet (27) connected to the first end of the exhalation channel, an exhalation valve located in the inhalation channel and opened only when a person inhales, an exhalation valve located in the exhalation channel and opened only when a person exhales, and a breathing chamber, wherein the breathing chamber is configured to deliver the inhaled mixture from the inhalation channel to the oral cavity or nasal cavity of the person when the person inhales, and to discharge the exhaled gas from the oral cavity or nasal cavity of the person to the exhalation channel when the person exhales, wherein the breathing chamber includes a first inlet connected to a second end of the inhalation channel, a second inlet connected to a second end of the exhalation channel, and a breathing inlet (28), during the person's inhalation, the inhaled mixture is delivered to the oral cavity or nasal cavity of the person through the breathing inlet (28), and during the person's exhalation, the exhaled gas is discharged from the oral cavity or nasal cavity of the person. The delivery device (2) is provided with an inhalation valve that opens only when a person inhales and an exhalation valve that opens only when a person exhales, thereby ensuring:

[0095] During inhalation by a person through the delivery device (2), only the inhalation mixture flows from the atomization chamber (6) to the oral or nasal cavity of the person;

[0096] During exhalation by a person through the delivery device (2), only exhaled air flows from the person's oral or nasal cavity to the filter (10).

[0097] According to another embodiment of the second disclosure, in order to fully ensure the unidirectional flow of the inhaled mixture when a person inhales and the unidirectional flow of the exhaled gas when a person exhales, the delivery device (2) may include (e.g. Fig.10 , Fig.11 and Fig.12) a housing (44) consisting of a first housing element (45) and a second housing element (46).

[0098] The channel element (47) and the breathing chamber (48) are located within the housing (44).

[0099] The channel element (47) comprises:

[0100] a tubular suction passage (49);

[0101] a tubular exhalation passage (50);

[0102] a suction mixture inlet (26) configured in the form of a nozzle and connected to a first end of the suction passage (49);

[0103] an exhalation gas outlet (27) configured in the form of a nozzle and connected to a first end of the exhalation channel (50);

[0104] an inhalation valve (51) located in the inhalation passage (49) and configured to open only when a person inhales;

[0105] an exhalation valve (52) located in the exhalation passage (50) and configured to open only when the person exhales;

[0106] The breathing chamber (48) comprises:

[0107] a first inlet (53) connected to the second end of the suction passage (49);

[0108] a second inlet (54) connected to a second end of the exhalation passage (50);

[0109] A respiratory inlet (28) through which an inhaled mixture is delivered to the oral or nasal cavity of the person during inhalation and through which exhaled gases are removed from the oral or nasal cavity of the person during exhalation.

[0110] The advantage of this embodiment of the second disclosure is the manufacturability of the conveying device (2), i.e., the simplicity of manufacturing the elements of the conveying device (2), and the simplicity of assembling the conveying device (2) from the manufactured elements. The configuration of the conveying device (2) according to this embodiment of the second disclosure ensures that:

[0111] During the inhalation of the person through the delivery device (2), only the inhaled mixture flows from the atomization chamber (6) to the oral or nasal cavity of the person;

[0112] During exhalation by a person through the delivery device (2), only exhaled air flows from the oral or nasal cavity of the person to the filter (10).

[0113] According to one of the embodiments of the first disclosure and the second disclosure, the atomization chamber (6) can be configured in such a manner (e.g. Figure 4 , 5 , 6, 7 and Figure 8 As shown, and a dosing device (9) attached to a housing (12), the housing (12) of the atomization chamber (6) is composed of an upper housing element (29) and a lower housing element (30), and the atomization chamber (6) includes a partition (38) which is located between the upper housing element (29) and the lower housing element (30).

[0114] The upper housing member (29) includes a main body portion (31), a first side portion (34) and a second side portion (35).

[0115] The main body (31) is constructed in the form of a hollow cylinder opened from below, and has a cylindrical side wall (32) and an upper end wall (33). The upper end wall (33) includes a suction mixture outlet (16) in the form of a nozzle.

[0116] The first side portion (34) and the second side portion (35) are connected to the lower portion of the cylindrical side wall (32) such that they are located at opposite sides of the cylindrical side wall (32) of the main body portion (31).

[0117] The first side portion (34) comprises an air supply inlet (14) in the form of a nozzle.

[0118] The second side portion (35) includes a deepening portion (36) through which air flows from the inner space of the lower housing element (30) to the inner space of the main body portion (31). The upper portion of the second side portion (35) includes a drug supply hole (15).

[0119] The lower housing element (30) comprises a longitudinal deepening (37), through the inner space of which air flows from the air supply inlet (14) to the inner space of the deepening (36) in the second side portion (35).

[0120] The atomization chamber (6) comprises a partition (38) located between the upper housing element (29) and the lower housing element (30) so as to separate the inner space of the longitudinally deepened portion (37) of the lower housing element (30) from the inner space of the main body (31). The portion of the partition (38) located below the air supply inlet (14) is provided with one or more holes (55), through which air flows from the air supply inlet (14) to the inner space of the longitudinally deepened portion (37). The portion of the partition (38) located below the drug supply hole (15) in the second side portion (35) comprises a hole (56), and the piezoelectric transducer (13) is located above or below the hole (56).

[0121] Due to the mutually opposed arrangement of the first side portion (34) and the second side portion (35), the presence of the partition (38) and the described construction of the partition (38), and in addition, since the internal space of the longitudinally deepened portion (37) in the lower housing element (30) is separated from the internal space of the main body portion (31) only by the partition (38), and there is no separation between the internal space of the longitudinally deepened portion (37) of the lower housing element (30) and the internal space of the deepened portion (36) in the second side portion (35), the longitudinally deepened portion (37) in the lower housing element (30) becomes a channel, and air flows from the air supply inlet (14) to the internal space of the deepened portion (36) in the second side portion (35) through the internal space of the channel, and in the channel, the liquid medicine is atomized into an aerosol. The air movement diagram in the atomization chamber (6) of this embodiment according to the first disclosure and the second disclosure is as shown in FIG. Figure 8 In addition, the air in the inner space of the longitudinal deepening portion (37) in the lower shell element (30) flows in one direction, and the air containing the drug aerosol flows in the opposite direction through the inner space of the deepening portion (36) in the second side portion (35) to the inner space of the main body portion (31), thereby causing turbulence of the airflow, enhancing the mixing of the drug aerosol and the air, and correspondingly achieving uniformity of the inhaled mixture inhaled when a person inhales.

[0122] According to one embodiment of the atomization chamber (6) described above, the atomization chamber (7) may include an air inlet valve (57) located below the one or more holes (55), which opens the one or more holes (55) when a person inhales and prevents air from leaving the atomization chamber (5) through the air supply inlet (14).

[0123] According to another embodiment, the interface (8) may include (eg Fig.13 , 14 and Fig.15The interface (8) may include a drug outlet (19) configured in the form of a hole, a first needle (39), wherein the first needle (39) is configured to have a through passage for piercing a stopper on a bottle containing the drug and conveying the drug from the bottle containing the drug to the drug outlet (19). In addition, the interface (8) may include an air inlet (40) configured in the form of a hole, a second needle (41), wherein the second needle (41) is configured to have a through passage for piercing a stopper on a bottle containing the drug and conveying air from the air inlet (40) to the bottle containing the drug. The first needle (39) has a shorter length, preferably so that the upper end of the first needle (39) is close to the stopper on the bottle containing the drug. In this case, most of the liquid drug can come out of the bottle containing the drug. The second needle (41) is longer, preferably, and the upper end of the second needle is close to the bottom of the bottle containing the drug. In this case, after the bottle containing the drug is inserted into the interface (8), the surface level of the drug will be lower than the upper end of the second needle (41), and the air from the environment can freely enter the upper part of the bottle containing the drug, and the pressure of the air in the environment and the bottle containing the drug will be equal. In order to transport the drug from the interface (8) to the quantitative device (9), the drug outlet (19) is connected to the drug inlet (20) of the quantitative device (9), wherein the flexible tube (58) is inserted into the drug outlet (9). In order to transport air to the air inlet (40), the flexible tube (59) is inserted into the hole of the air inlet (40). The embodiment of the interface (8) enables the use of a standard bottle of drug sealed with a rubber stopper in the claimed inhalation device (1) and inhalation system (3) for administration by inhalation. In order to protect the bottle containing the drug inserted into the interface (8) from displacement or damage, the interface (8) can have a protective cover (60), which is installed on the interface (8) and covers the bottle containing the drug from above.

[0124] According to another embodiment, the inhalation system (3) comprises a plug configured to close the respiratory inlet (28) of the conveying device (2), and the inhalation device (1) for administering the drug by inhalation comprises an element (11) for forming an airflow, which is configured to force the airflow to form in the inhaled mixture forming pipeline and / or the exhaled gas purification pipeline. The element (11) for forming the airflow comprises an air inlet (42) and an air outlet (43), and is electrically connected to the control unit (5). As the element (11) for forming the airflow, any article and / or device capable of forming the airflow, such as a fan, can be used.

[0125] There are some embodiments according to which the element (11) for forming an air flow can be installed in an inhalation device (1) for administering a drug by inhalation. Fig.18), the element (11) for forming the air flow is installed in the pipeline for conveying the inhaled mixture to the human body, so that the air outlet (43) of the element (11) for forming the air flow is connected to the air inlet (17) of the inhalation sensor (7). According to another embodiment (as shown in FIG. Fig.19 ), the element (11) for forming the air flow is installed in the pipeline for delivering the inhaled mixture to the human body, so that the air inlet (42) of the element (11) for forming the air flow is connected to the air outlet (18) of the inhalation sensor (7), and the air outlet (43) of the element (11) for forming the air flow is connected to the air supply inlet (14) of the housing (12) of the atomization chamber (6). According to another embodiment (as shown in FIG. Fig. 20 As shown in the schematic diagram in FIG. 1 , the element (11) for forming an air flow is installed in the exhaled gas purification line so that the air inlet (42) of the element (11) for forming an air flow is connected to the purified air outlet (23) of the filter (10).

[0126] The presence of the element (11) for forming the air flow and the plug for closing the respiratory inlet (28) of the delivery device (2) enables the inhalation system (3) to discharge drug residues. This discharge is necessary when volatile anesthetics (e.g. methoxyflurane) are used as drugs for administration to humans.

[0127] The discharge process of the inhalation system (3) is as follows. After inhalation using the inhalation system (3), the plug is placed in the respiratory inlet (28) of the delivery device (2). Using the control unit (5), the system discharge option is selected, after which the control unit supplies power to the element for forming the airflow (11). After supplying power to the element for forming the airflow (11), the element for forming the airflow (11) generates a forced airflow through the inhalation sensor (7), the atomization chamber (6), the flexible tube (24), the delivery device (2), the flexible tube (25) and the filter (10). After a period of time, the control unit (5) stops supplying power to the element for forming the airflow (11), after which the plug is removed from the respiratory inlet (28) of the delivery device (2), and the device is ready for further use.

[0128] The inhalation device (1) for administering drugs by inhalation, as well as the corresponding inhalation system (3), can be implemented both in a stationary mode powered by a 220 volt or 110 volt network, and in a mobile mode powered by a power supply element (such as an accumulator or battery). The mobile mode allows the inhalation system (3) to be used in various situations, for example, in emergency situations at the scene of an incident, when a person may be injured and requires anesthesia with a volatile anesthetic. Considering that the air temperature in winter is below zero degrees, anesthesia with volatile anesthetics and the use of air at such a low temperature will be problematic and ineffective, because the volatile anesthetic will condense in the nebulizer chamber (6), the flexible tubes (24) and (25) and the delivery device (2). In order to prevent this problem, the inhalation system (3) can include a heating element.

[0129] In one embodiment, the inhalation device (1) for administering a drug by inhalation may include at least one heating element, which is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5). In this case, the one or more heating elements that heat the housing (12) of the atomization chamber (6) from the outside are located in the housing (4).

[0130] In another embodiment, the atomizing chamber (6) may include at least one heating element, which is configured to heat the housing (12) of the atomizing chamber (6) and is configured to be electrically connected to the control unit (5). In this case, one or more heating elements that directly heat the housing (12) of the atomizing chamber (6) are located in the housing (12) of the atomizing chamber (6).

[0131] In another embodiment, the atomizing chamber (6) may include at least one heating element, which is configured to heat the air or the inhaled mixture in the housing (12) of the atomizing chamber (6) and is configured to be electrically connected to the control unit (5). In this case, one or more heating elements that directly heat the air or the inhaled mixture in the housing (12) of the atomizing chamber (6) are located in the housing (12) of the atomizing chamber (6).

[0132] In another embodiment, the flexible tube (24) comprises at least one heating element, which is configured to heat the flexible tube (24) or the inhaled mixture passing through the flexible tube (24) and is electrically connected to the control unit (5). In this case, the flexible tube (24) has one or more heating elements, which either directly heat the material of the flexible tube (24) or directly heat the inhaled mixture passing through the flexible tube (24).

[0133] In another embodiment, the flexible tube (25) comprises at least one heating element, which is configured to heat the flexible tube (25) or the exhaled gas passing through the flexible tube (25) and is electrically connected to the control unit (5). In this case, the flexible tube (25) has one or more heating elements inside, which either directly heat the material of the flexible tube (25) or directly heat the exhaled gas passing through the flexible tube (25).

[0134] It is obvious to a person skilled in the art that different embodiments of the heating element arrangement may be combined in different structural elements of the inhalation system (3).

[0135] Since the convenience of inhalation requires the use of a product (e.g., a mouthpiece, a mouthpiece, or a mask) that enables the inhalation mixture to be conveniently delivered to a person's oral or nasal cavity, the inhalation system (3) may include a mouthpiece or a mask configured to be connected to the respiratory inlet (28) of the delivery device (2). Figure 3 An embodiment of an inhalation system (3) is shown, wherein a mouthpiece is connected to the breathing inlet (28) of the delivery device (2).

[0136] The technical contribution of the claimed inhalation device (1) and inhalation system (3) for administering a drug by inhalation lies in the following aspects:

[0137] -Prevent drug vapors (e.g., volatile anesthetics) from entering the environment;

[0138] - Prevent unnecessary drug losses during the loading phase of the drug into the inhalation device or inhalation system, thereby achieving greater economy in drug dosage;

[0139] - Greater safety for patients, i.e. precise and controlled drug dosing to avoid overdose and adverse side effects;

[0140] - Provide greater safety for people, i.e., since the drug does not escape into the environment, there is no risk of inhalation of the drug by non-target groups and people who do not need the drug;

[0141] - Convenience and versatility in use, i.e. the inhalation device can be used with any acceptable delivery device (mouthpiece, mouthpiece or mask), in particular as part of the claimed inhalation system, which ensures maximum convenience and efficiency for the user, as well as various modes of drug delivery (through the nasal cavity or the mouth).

[0142] The examples given are merely illustrative of the claimed subject matter and do not limit them.

Claims

1. An inhalation device for administering a drug by inhalation, characterized in that The inhalation device comprises a housing (4), a pipeline for delivering an inhalation mixture to a human body, an exhalation gas purification pipeline, and a control unit (5) located in the housing (4), wherein the pipeline for delivering an inhalation mixture to a human body comprises a nebulizer chamber (6), an inhalation sensor (7), an interface (8) configured to be connected to a bottle containing a drug, and a metering device (9), wherein the exhalation gas purification pipeline comprises a filter (10) configured to purify the drug in the exhaled gas of a person, wherein the nebulizer chamber (6) comprises a housing (12) and a piezoelectric transducer (13), wherein the piezoelectric transducer (13) is located in the housing (12) of the nebulizer chamber and is configured to form an aerosol of the drug, wherein the housing (12) of the nebulizer chamber (6) comprises an air supply inlet (14), a drug supply hole (15) and an inhalation mixture outlet (16), wherein the inhalation sensor (7) comprises an air inlet (17) and an air outlet (18), wherein the interface (8) comprises a drug outlet (19), wherein the The doser (9) is configured to deliver the drug from the interface (8) to the piezoelectric transducer (13), and comprises a drug inlet (20) and a drug outlet (21), wherein the filter (10) comprises an inlet (22) through which exhaled air enters, and comprises a purified air outlet (23), wherein the air outlet (18) of the inhalation sensor (7) is connected to the air supply inlet (14) of the housing (12) of the nebulization chamber (6), wherein the drug outlet (19) of the interface (8) is connected to the drug inlet (20) of the doser (9), wherein the drug outlet (21) of the doser (9) passes through the drug supply hole (15) of the housing (12) of the nebulization chamber (6), wherein the inhalation sensor (7) is electrically connected to the control unit (5), the piezoelectric transducer (13) is electrically connected to the control unit (5), and the doser (9) is electrically connected to the control unit (5).

2. The inhalation device according to claim 1, characterized in that The atomizing chamber (6) is configured in the following manner, that is, the housing (12) of the atomizing chamber (6) is composed of an upper housing element (29) and a lower housing element (30), and the upper housing element (29) includes a main body part (31) in the form of a hollow cylinder opened from below, having a cylindrical side wall (32) and an upper end wall (33), wherein the upper end wall (33) includes an inhaled mixture outlet (16) in the form of a nozzle, and is composed of a first side part (34) and a second side part (35) connected to the lower part of the cylindrical side wall (32) so that they are located on opposite sides of the cylindrical side wall (32), wherein the first side part (34) includes an air supply inlet (14) in the form of a nozzle, and the second side part (35) includes a deepening part (36), air flows from the inner space of the lower housing element (30) through the inner space of the deepening part (36) to the inner space of the main body part (31), and the second side part (35) 5) includes a drug supply hole (15), the lower shell element (30) includes a longitudinal deepening portion (37), and air flows from the air supply inlet (14) to the internal space of the deepening portion (36) through the internal space of the longitudinal deepening portion, wherein the atomization chamber (6) also includes a partition (38) located between the upper shell element (29) and the lower shell element (30), the partition (38) separates the internal space of the longitudinal deepening portion (37) from the internal space of the main body (31), the portion of the partition (38) located below the air supply inlet (14) is provided with one or more holes (55), and air flows from the air supply inlet (14) to the internal space of the longitudinal deepening portion (37) through the one or more holes, and the portion of the partition (38) located below the drug supply hole (15) includes a hole (56), and the piezoelectric transducer (13) is located above or below the hole (56).

3. An inhalation device according to any one of claims 1 to 2, characterized in that The atomizing chamber (6) further comprises an air inlet valve (57), which is configured to introduce air into the atomizing chamber (6) through the air supply inlet (14) and prevent air from escaping from the atomizing chamber (6) through the air supply inlet (14), and the air inlet valve (57) is located at the air supply inlet (14) of the housing (12) of the atomizing chamber (6) or near the air supply inlet (14).

4. An inhalation device according to any one of claims 1 to 3, characterized in that The interface (8) further comprises a first needle (39) which is configured to have a through passage for piercing a stopper on a bottle containing a drug and delivering the drug from the bottle containing the drug to the drug outlet (19) of the interface (8).

5. The inhalation device according to claim 4, characterized in that The interface (8) also includes an air inlet (40) and a second needle (41), which is configured to have a through channel for piercing a stopper on a bottle containing the drug and delivering air from the air inlet (40) to the bottle containing the drug.

6. An inhalation device according to any one of claims 1 to 5, characterized in that The inhalation sensor (7) is configured to provide a signal to the control unit (5) when a person inhales, and the control unit (5) is configured to power the metering device (9) only when a signal is received from the inhalation sensor (7) during the person's inhalation, so that the metering device (9) delivers a dose of the drug to the nebulization chamber (6).

7. An inhalation device according to any one of claims 1 to 6, characterized in that The pipeline for conveying an inhaled mixture to a human body further comprises an element (11) for forming an airflow, which is configured to forcibly form an airflow in the inhaled mixture pipeline and / or the exhaled gas purification pipeline, and is configured to comprise an air inlet (42) and an air outlet (43), wherein the element (11) for forming an airflow is electrically connected to the control unit (5), and the air outlet (43) of the element (11) for forming an airflow is connected to the air inlet (17) of the inhalation sensor (7).

8. An inhalation device according to any one of claims 1 to 6, characterized in that The pipeline for delivering an inhaled mixture to a human body further comprises an element (11) for forming an airflow, which is configured to force an airflow in the inhaled mixture pipeline and / or the exhaled gas purification pipeline, and is configured to include an air inlet (42) and an air outlet (43), wherein the element (11) for forming an airflow is electrically connected to the control unit (5), the air inlet (42) of the element (11) for forming an airflow is connected to the air outlet (18) of the inhalation sensor (7), and the air outlet (43) of the element (11) for forming an airflow is connected to the air supply inlet (14) of the housing (12) of the atomization chamber (6).

9. An inhalation device according to any one of claims 1 to 6, characterized in that The exhaled gas purification line further comprises an element (11) for forming an airflow, which is configured to forcibly form an airflow in the inhaled mixture forming line and / or the exhaled gas purification line, and is configured to include an air inlet (42) and an air outlet (43), wherein the element (11) for forming an airflow is electrically connected to the control unit (5), and the air inlet (42) of the element (11) for forming an airflow is connected to the purified air outlet (23) of the filter (10).

10. An inhalation device according to any one of claims 7 to 9, characterized in that A fan is used as an element (11) for forming an air flow.

11. An inhalation device according to any one of claims 1 to 10, characterized in that The inhalation device further comprises at least one heating element, which is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

12. An inhalation device according to any one of claims 1 to 10, characterized in that The atomization chamber (6) further comprises at least one heating element, wherein the at least one heating element is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

13. An inhalation device according to any one of claims 1 to 10, characterized in that The atomization chamber (6) further comprises at least one heating element, which is configured to heat the air or the inhaled mixture in the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

14. An inhalation device according to any one of claims 1 to 13, characterized in that The volatile anesthetic is methoxyflurane.

15. An inhalation system (3), characterized in that The inhalation system comprises an inhalation device (1) for administering drugs by inhalation, a delivery device (2), a flexible tube (24) and a flexible tube (25), wherein the delivery device (2) is configured to deliver an inhalation mixture from the inhalation device (1) for administering drugs by inhalation to the oral cavity or nasal cavity of the person when the person inhales, and to deliver exhaled gas from the oral cavity or nasal cavity of the person back to the inhalation device (1) for administering drugs by inhalation when the person exhales, wherein the inhalation device (1) for administering drugs by inhalation comprises a housing (4), a pipeline for delivering the inhalation mixture to the human body, an exhaled gas purification pipeline, and a control unit (5) located in the housing (4), wherein the pipeline for delivering the inhalation mixture to the human body comprises an atomization chamber (6), an inhalation sensor (7 ), an interface (8) configured to connect a bottle containing a drug, and a dosing device (9), wherein the exhaled gas purification line includes a filter (10) configured to purify the drug in the exhaled gas of a person, wherein the nebulizer chamber (6) includes a shell (12) and a piezoelectric transducer (13), wherein the piezoelectric transducer (13) is located in the shell (12) of the nebulizer chamber and is configured to form an aerosol of the drug, wherein the shell (12) of the nebulizer chamber (6) includes an air supply inlet (14), a drug supply hole (15) and an inhaled mixture outlet (16), wherein the inhalation sensor (7) includes an air inlet (17) and an air outlet (18), wherein the interface (8) includes a drug outlet (19), and wherein the The doser (9) is configured to deliver the drug from the interface (8) to the piezoelectric transducer (13), and comprises a drug inlet (20) and a drug outlet (21), wherein the filter (10) comprises an inlet (22) through which exhaled air enters, and comprises a purified air outlet (23), wherein the air outlet (18) of the inhalation sensor (7) is connected to the air supply inlet (14) of the housing (12) of the nebulizer chamber (6), wherein the drug outlet (19) of the interface (8) is connected to the drug inlet (20) of the doser (9), wherein the drug outlet (21) of the doser (9) passes through the drug outlet (22) of the housing (12) of the nebulizer chamber (6) and enters the nebulizer chamber (6). The invention relates to a material supply hole (15), wherein the inhalation sensor (7) is electrically connected to the control unit (5), the piezoelectric transducer (13) is electrically connected to the control unit (5), and the metering device (9) is electrically connected to the control unit (5), wherein the delivery device (2) comprises an inhalation mixture inlet (26), an exhalation gas outlet (27) and a breathing inlet (28), and when a human body inhales, the inhalation mixture is delivered to the human oral cavity or nasal cavity through the breathing inlet, and when a human body exhales, the exhalation gas is discharged from the human oral cavity or nasal cavity through the breathing inlet, wherein a first end of the flexible tube (24) is connected to the inhalation mixture outlet (16) of the housing (12) of the atomization chamber (6),The second end of the flexible tube (24) is connected to the inhaled mixture inlet (26) of the delivery device (2), wherein the first end of the flexible tube (25) is connected to the inlet (22) of the filter (10), and the second end of the flexible tube (25) is connected to the exhaled gas outlet (27) of the delivery device (2).

16. The inhalation system according to claim 15, characterized in that The atomizing chamber (6) is configured in the following manner, that is, the housing (12) of the atomizing chamber (6) is composed of an upper housing element (29) and a lower housing element (30), and the upper housing element (29) includes a main body part (31) in the form of a hollow cylinder opened from below, having a cylindrical side wall (32) and an upper end wall (33), wherein the upper end wall (34) includes an inhaled mixture outlet (16) in the form of a nozzle, and is composed of a first side part (34) and a second side part (35) connected to the lower part of the cylindrical side wall (32) so that they are located on opposite sides of the cylindrical side wall (32), wherein the first side part (34) includes an air supply inlet (14) in the form of a nozzle, and the second side part (35) includes a deepening part (36), air flows from the inner space of the lower housing element (30) through the inner space of the deepening part (36) to the inner space of the main body part (31), and the second side part (35) 5) includes a drug supply hole (15), the lower shell element (30) includes a longitudinal deepening portion (37), and air flows from the air supply inlet (14) to the internal space of the deepening portion (36) through the internal space of the longitudinal deepening portion, wherein the atomization chamber (6) also includes a partition (38) located between the upper shell element (29) and the lower shell element (30), the partition (38) separates the internal space of the longitudinal deepening portion (37) from the internal space of the main body (31), the portion of the partition (38) located below the air supply inlet (14) is provided with one or more holes (55), and air flows from the air supply inlet (14) to the internal space of the longitudinal deepening portion (37) through the one or more holes, and the portion of the partition (38) located below the drug supply hole (15) includes a hole (56), and the piezoelectric transducer (13) is located above or below the hole (56).

17. An inhalation system according to any one of claims 15-16, characterized in that The atomizing chamber (6) comprises an air inlet valve (57), which is configured to introduce air into the atomizing chamber (6) through the air supply inlet (14) and prevent air from escaping from the atomizing chamber (6) through the air supply inlet (14), and the air inlet valve (57) is located at the air supply inlet (14) of the housing (12) of the atomizing chamber (6) or near the air supply inlet (14).

18. An inhalation system according to any one of claims 15 to 17, characterized in that The delivery device (2) comprises an inhalation channel for delivering the inhalation mixture to a human body, an inhalation mixture inlet (26) connected to a first end of the inhalation channel, an exhalation channel for discharging exhaled gas, an exhalation gas outlet (27) connected to the first end of the exhalation channel, an exhalation valve located in the inhalation channel and opened only during a person's inhalation, an exhalation valve located in the exhalation channel and opened only during a person's exhalation, and a breathing chamber, wherein the breathing chamber is configured to deliver the inhalation mixture from the inhalation channel to the oral cavity or nasal cavity of the person when the person inhales, and to discharge the exhaled gas from the oral cavity or nasal cavity of the person to the exhalation channel when the person exhales, wherein the breathing chamber comprises a first inlet connected to a second end of the inhalation channel, a second inlet connected to a second end of the exhalation channel, and a breathing inlet (28), wherein during a person's inhalation, the inhalation mixture is delivered to the oral cavity or nasal cavity of the person through the breathing inlet (28), and during a person's exhalation, the exhaled gas is discharged from the oral cavity or nasal cavity of the person.

19. An inhalation system according to any one of claims 15 to 17, characterized in that The delivery device (2) comprises a housing (44), a channel element (47) located in the housing (44) and a breathing chamber (48) located in the housing (44), wherein the housing (44) comprises a first housing element (45) and a second housing element (46), wherein the channel element (47) comprises a tubular inhalation channel (49), a tubular exhalation channel (50), an inhalation mixture inlet (26) configured in the form of a nozzle and connected to a first end of the inhalation channel (49), an exhalation gas outlet (27) configured in the form of a nozzle and connected to the exhalation channel (50), ), an inhalation valve (51) located in the inhalation channel (49) and opened only when a person inhales, an exhalation valve (52) located in the exhalation channel (50) and opened only when a person exhales, the breathing chamber (48) includes a first inlet (53) connected to the second end of the inhalation channel (49), a second inlet (54) connected to the second end of the exhalation channel (50), and a breathing inlet (28), through which the inhaled mixture is delivered to the oral cavity or nasal cavity of the person when the person inhales, and the exhaled gas is discharged from the oral cavity or nasal cavity of the person when the person exhales.

20. An inhalation system according to any one of claims 15 to 19, characterized in that The interface (8) further comprises the first needle (39), which is configured to have a through passage for piercing a stopper on a bottle containing a drug and delivering the drug from the bottle containing the drug to the drug outlet (19) of the interface (8).

21. The inhalation system according to claim 21, characterized in that The interface (8) also includes an air inlet (40) and a second needle (41), which is configured to have a through channel for piercing a stopper on a bottle containing the drug and delivering air from the air inlet (40) to the bottle containing the drug.

22. An inhalation system according to any one of claims 15 to 21, characterized in that The inhalation sensor (7) is configured to provide a signal to the control unit (5) when a person inhales, and the control unit (5) is configured to power the metering device (9) only when a signal is received from the inhalation sensor (7) during the person's inhalation, so that the metering device (9) delivers a dose of the drug to the nebulization chamber (6).

23. The air inhalation system according to any one of claims 15 to 22, characterized in that The inhalation system further comprises a plug configured to close the breathing inlet (28) of the delivery device (2), and the pipeline for delivering the inhalation mixture to the human body further comprises an element for forming an airflow (11), which is configured to forcibly form an airflow in the inhalation mixture forming pipeline and / or the exhalation gas purification pipeline, and is configured to include an air inlet (42) and an air outlet (43), wherein the element for forming an airflow (11) is electrically connected to the control unit (5), and the air outlet (43) of the element for forming an airflow (11) is connected to the air inlet (17) of the inhalation sensor (7).

24. The air inhalation system according to any one of claims 15 to 22, characterized in that The inhalation system also includes a plug configured to close the breathing inlet (28) of the delivery device (2), and the pipeline for delivering the inhalation mixture to the human body also includes an element (11) for forming an airflow, which is configured to force an airflow in the inhalation mixture forming pipeline and / or the exhalation gas purification pipeline, and is configured to include an air inlet (42) and an air outlet (43), and the element (11) for forming an airflow is electrically connected to the control unit (5), the air inlet (42) of the element (11) for forming an airflow is connected to the air outlet (18) of the inhalation sensor (7), and the air outlet (43) of the element (11) for forming an airflow is connected to the air supply inlet (14) of the housing (12) of the atomization chamber (6).

25. The air inhalation system according to any one of claims 15 to 22, characterized in that The inhalation system further comprises a plug configured to close the breathing inlet (28) of the delivery device (2), and the exhaled gas purification line further comprises an element (11) for forming an airflow, which is configured to force an airflow in the inhaled mixture forming line and / or the exhaled gas purification line, and is configured to include an air inlet (42) and an air outlet (43), wherein the element (11) for forming an airflow is electrically connected to the control unit (5), and the air inlet (42) of the element (11) for forming an airflow is connected to the purified air outlet (23) of the filter (10).

26. An inhalation system according to any one of claims 23 to 25, characterized in that A fan is used as an element (11) for forming an air flow.

27. An inhalation system according to any one of claims 15 to 26, characterized in that The inhalation device (1) for administering a drug by inhalation further comprises at least one heating element, which is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

28. An inhalation system according to any one of claims 15 to 26, characterized in that The atomization chamber (6) further comprises at least one heating element, wherein the at least one heating element is configured to heat the housing (12) of the atomization chamber (6) and is configured to be electrically connected to the control unit (5).

29. An inhalation system according to any one of claims 15 to 26, characterized in that The atomizing chamber (6) further comprises at least one heating element, wherein the at least one heating element is configured to heat the air or the inhaled mixture in the housing (12) of the atomizing chamber (6) and is configured to be electrically connected to the control unit (5).

30. An inhalation system according to any one of claims 15 to 29, characterized in that The flexible tube (24) comprises at least one heating element, which is configured to heat the flexible tube (24) or heat the inhaled mixture passing through the flexible tube (24) and is configured to be electrically connected to the control unit (5).

31. The air inhalation system according to any one of claims 15 to 30, characterized in that The flexible tube (25) includes at least one heating element, which is configured to heat the flexible tube (25) or heat the exhaled gas passing through the flexible tube (25) and is configured to be electrically connected to the control unit (5).

32. An inhalation system according to any one of claims 15 to 31, characterized in that The inhalation system also includes a mouthpiece, a mouthpiece or a mask, each of which is configured to be connected to the respiratory inlet (28) of the delivery device (2).

33. An inhalation system according to any one of claims 14 to 32, characterized in that The volatile anesthetic is methoxyflurane.

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