Blood coagulation detection device for medical sample

Abstract

The invention discloses a blood coagulation detection device for a medical sample. The blood coagulation detection device is used for reducing the difficulty of blood coagulation detection in a blood sample. The device comprises at least two light source emission modules, a light source integration module, a blood sample test tube and a blood coagulation detection module, the light source emitting module comprises a light beam emitter and a prism, and the light beam emitter is perpendicular to the cylindrical surface of the prism; the light beam integration module is provided with at least two incident areas and an emergent port, the prisms of the at least two light source emitting modules are placed on the rear side of the light beam integration module, so that the emergent cylindrical surface of each prism corresponds to one incident area of the light beam integration module, and the number of the incident areas is larger than or equal to that of the light source emitting modules. The light beam integration module is used for integrating light beams emitted by the emergent cylindrical surface of the prism; the blood sample test tube is arranged on the front side of an exit port of the light beam integration module; the blood coagulation detection module is positioned on one side of the blood sample test tube.

Description

Technical Field

[0001] The embodiments of the present application relate to the field of coagulation detection, and in particular to a coagulation detection device for medical samples. Background Art

[0002] As people pay more attention to their physical health, more and more people regularly evaluate their physical condition through blood tests, or draw blood and store it for future use.

[0003] With the storage of a large number of blood samples, the status of the blood samples needs to be monitored at all times, and abnormal blood samples need to be screened out. In the prior art, waste blood samples require personnel to judge the quality of each blood sample in turn and screen out the waste blood samples, but the placement angle of the blood samples is not suitable, and the placement angle of the samples needs to be adjusted one by one, which consumes a lot of manpower and is extremely inefficient.

[0004] In the prior art, coagulation analysis equipment is used to automatically detect blood samples, which is different from general coagulation detection. General coagulation detection is performed by adding coagulants to the blood samples, and then performing optical detection or magnetic bead detection through the detection equipment. In the process of detecting waste blood samples in bath products, in order to ensure that the blood samples are not contaminated, magnetic bead detection cannot be used, and only optical detection can be used. The emission light beam in the optical detection usually cannot meet the detection requirements of blood. Therefore, different types of emission light sources need to be prepared in advance to solve the defect of small detection range. However, the preparation of different types of emission light sources currently requires the intervention of multiple equipment, which not only increases the volume of the detection device, but also increases the cost, greatly increasing the difficulty of blood sample coagulation detection. Summary of the invention

[0005] The present application discloses a blood coagulation detection device for medical samples, which is used to reduce the difficulty of blood coagulation detection in blood samples.

[0006] The present application provides a blood coagulation detection device for a medical sample, comprising:

[0007] At least two light source emission modules, a light source integration module, a blood sample tube and a coagulation detection module;

[0008] The light source emission module includes a light beam emitter and a prism. The light beam emitter is placed perpendicular to the cylindrical surface of the prism. The prism includes at least three cylindrical surfaces. The cylindrical surface of the prism perpendicular to the light beam emitter is the incident cylindrical surface, and the cylindrical surface from which the light beam emerges is the exit cylindrical surface.

[0009] The beam integration module is provided with at least two incident areas and one exit port, and the prisms of at least two light source emission modules are placed on the rear side of the beam integration module, so that the exit cylindrical surface of each prism corresponds to one of the incident areas of the beam integration module, and the number of the incident areas is greater than or equal to the number of the light source emission modules. The beam integration module is used to integrate the light beams emitted from the exit cylindrical surfaces of the prisms;

[0010] The blood sample tube is arranged in front of the light beam integration module's exit port;

[0011] The coagulation detection module is located on one side of the blood sample tube.

[0012] Optionally, the light source emission module further includes a beam screening plate;

[0013] The beam screening plate is placed on the front side of the beam exiting column of the prism;

[0014] The beam screening plate is provided with a beam transmission area;

[0015] The beam screening plate is provided with a displacement assembly.

[0016] Optionally, the beam integration module includes a pyramid, and the pyramid has at least three conical surfaces;

[0017] The incident area is a cone surface;

[0018] The exit ports are the corresponding vertices of the three cone surfaces.

[0019] Optionally, the beam integration module further includes a first rotating motor;

[0020] The first rotating motor is arranged on the bottom surface of the pyramid.

[0021] Optionally, the light source emission module further includes a first condensing lens;

[0022] The first condenser lens is located between the light beam emitter and the prism.

[0023] Optionally, the light source emission module further includes a second rotating motor;

[0024] The second rotating motor is arranged on the top surface or the ground of the prism.

[0025] Optionally, the blood coagulation detection device further includes a light-transmitting plate, a light-splitting optical fiber, and at least two second condensing lenses;

[0026] The splitting fiber includes an input fiber and at least two output fibers;

[0027] The input optical fiber is arranged in front of the light-transmitting hole of the light-transmitting plate, and the light-transmitting hole of the light-transmitting plate corresponds to the position of the exit port of the beam integration module;

[0028] The second condensing lens is arranged in front of the output optical fiber.

[0029] Optionally, the coagulation detection module includes a filter lens and an optical image analyzer;

[0030] The filter lens is arranged between the blood sample tube and the optical image analyzer.

[0031] Optionally, the coagulation detection device further comprises an assembler;

[0032] The assembler is sequentially provided with a front light incident area, a test tube area and a rear light detection area;

[0033] The blood sample test tubes are arranged in the test tube area;

[0034] The second condenser lens is arranged in the front light incident area;

[0035] The filter lens and the optical image analyzer are arranged in the post-light detection area.

[0036] Optionally, a plane light-transmitting area is provided in the middle of the blood sample tube.

[0037] It can be seen from the above technical solutions that the embodiments of the present application have the following advantages:

[0038] In the present application, a blood coagulation detection device for medical samples specifically includes the following components: at least two light source emission modules, a light source integration module, a blood sample tube and a blood coagulation detection module. The connection method of the various components of the blood coagulation detection device is as follows: the light source emission module includes a light beam emitter and a prism, the light beam emitter is placed perpendicular to the cylindrical surface of the prism, the prism includes at least 3 cylindrical surfaces, the cylindrical surface of the prism perpendicular to the light beam emitter is the incident cylindrical surface, and the cylindrical surface where the light beam emerges is the exit cylindrical surface. At least two incident areas and one exit port are provided on the light beam integration module, and the prisms of at least two light source emission modules are placed on the rear side of the light beam integration module so that the exit cylindrical surface of each prism corresponds to one of the incident areas of the light beam integration module, and the number of incident areas is greater than or equal to the light source emission module, and the light beam integration module is used to integrate the light beam emitted from the exit cylindrical surface of the prism. The blood sample tube is arranged in front of the exit port of the light beam integration module. The blood coagulation detection module is located on one side of the blood sample tube.

[0039] The light beam is emitted by the light beam emitter, so that the light beam reaches the incident cylinder of the prism, and will be refracted to split the light into light beams of different wavelengths, which are emitted through the exit cylinder, and the light beams of different wavelengths will enter the light beam integration module. The light beam integration module will receive the light beams emitted by at least two prisms, and these light beams will be superimposed to form an integrated light beam after integration, and will be projected into the blood sample tube through the exit port, and finally through the blood sample tube, the coagulation detection module will perform data analysis by photographing the blood sample tube or receiving the light parameters passing through the blood sample tube to determine whether coagulation occurs. Since the prism can split the light beam and can integrate the light by selecting a certain area of ​​the split light beam, the requirements of the light beam emitter are reduced, and the types of integrated light beams are increased. Compared with the traditional method of making different types of light beams, it is simpler and does not require the intervention of multiple devices, which greatly reduces the volume of the detection device and reduces the difficulty of coagulation detection in blood samples. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0041] Figure 1 A schematic diagram of the structure of a blood coagulation detection device for medical samples in the present application;

[0042] Figure 2 is a structural diagram of the assembler in this application;

[0043] Figure 3 It is a schematic diagram of the structure of the blood sample tube in this application. DETAILED DESCRIPTION

[0044] In the following description, specific details such as specific system structures, technologies, etc. are provided for the purpose of illustration rather than limitation, so as to provide a thorough understanding of the embodiments of the present application. However, it should be clear to those skilled in the art that the present application may also be implemented in other embodiments without these specific details. In other cases, detailed descriptions of well-known systems, devices, circuits, and methods are omitted to prevent unnecessary details from obstructing the description of the present application.

[0045] It should be understood that when used in the present specification and the appended claims, the term "comprising" indicates the presence of described features, wholes, steps, operations, elements and / or components, but does not exclude the presence or addition of one or more other features, wholes, steps, operations, elements, components and / or combinations thereof.

[0046] It should also be understood that the term “and / or” used in the specification and appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes these combinations.

[0047] As used in the specification and appended claims of this application, the term "if" can be interpreted as "when" or "uponce" or "in response to determining" or "in response to detecting", depending on the context. Similarly, the phrase "if it is determined" or "if [described condition or event] is detected" can be interpreted as meaning "uponce it is determined" or "in response to determining" or "uponce [described condition or event] is detected" or "in response to detecting [described condition or event]", depending on the context.

[0048] In addition, in the description of the present application specification and the appended claims, the terms "first", "second", "third", etc. are only used to distinguish the descriptions and cannot be understood as indicating or implying relative importance.

[0049] References to "one embodiment" or "some embodiments" etc. described in the specification of this application mean that one or more embodiments of the present application include specific features, structures or characteristics described in conjunction with the embodiment. Therefore, the statements "in one embodiment", "in some embodiments", "in some other embodiments", "in some other embodiments", etc. that appear in different places in this specification do not necessarily refer to the same embodiment, but mean "one or more but not all embodiments", unless otherwise specifically emphasized in other ways. The terms "including", "comprising", "having" and their variations all mean "including but not limited to", unless otherwise specifically emphasized in other ways.

[0050] In the existing technology, as a large number of blood samples are stored, the status of the blood samples needs to be monitored at all times, and abnormal blood samples need to be screened out. In the existing technology, waste blood samples require personnel to judge the quality of each blood sample in turn and screen out the waste blood samples, but the placement angle of the blood samples is not suitable, and the placement angle of the samples needs to be adjusted one by one, which consumes a lot of manpower and is extremely inefficient.

[0051] In the prior art, coagulation analysis equipment is used to automatically detect blood samples, which is different from general coagulation detection. General coagulation detection is performed by adding coagulants to the blood sample, and then performing optical detection or magnetic bead detection through the detection equipment. In the process of detecting waste blood samples in toiletries, in order to ensure that the blood samples are not contaminated, magnetic bead detection cannot be used, and only optical detection can be used. The emission light beam in the optical detection is usually a single light source, and the wavelength range of the spectrum of the light source is limited, which cannot meet the various detection requirements of blood. Therefore, it is necessary to prepare emission light sources of different wavelengths in advance to solve the defect of small detection range. However, the preparation of emission light sources of different wavelengths currently requires the installation and embedding of multiple devices, which greatly increases the difficulty of blood sample coagulation detection.

[0052] Based on this, the present application discloses a blood coagulation detection device for medical samples, which is used to reduce the difficulty of blood coagulation detection in blood samples.

[0053] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0054] See also Figure 1 , Figure 2 and Figure 3 The present application provides an embodiment of a blood coagulation detection device for a medical sample, comprising:

[0055] At least two light source emission modules 1, a light source integration module 2, a blood sample tube 3 and a coagulation detection module 4;

[0056] The light source emission module 1 includes a light beam emitter 5 and a prism 6. The light beam emitter 5 is placed perpendicular to the cylindrical surface of the prism 6. The prism 6 includes at least three cylindrical surfaces. The cylindrical surface of the prism 6 perpendicular to the light beam emitter 5 is the incident cylindrical surface, and the cylindrical surface from which the light beam emerges is the exit cylindrical surface.

[0057] The beam integration module is provided with at least two incident areas and one exit port, and the prisms 6 of at least two light source emission modules 1 are placed on the rear side of the beam integration module, so that the exit cylindrical surface of each prism 6 corresponds to one of the incident areas of the beam integration module, and the number of the incident areas is greater than or equal to the number of the light source emission modules 1. The beam integration module is used to integrate the light beams emitted from the exit cylindrical surfaces of the prisms 6;

[0058] The blood sample tube 3 is arranged in front of the light beam integration module's outlet;

[0059] The blood coagulation detection module 4 is located on one side of the blood sample tube 3 .

[0060] In this embodiment, the light source emission module 1 includes a light beam emitter 5 and a prism 6. The light beam emitter 5 can emit a light beam set of a respective wavelength, and the prism 6 is used to split the light beam sets of different wavelengths.

[0061] Furthermore, the light beam emitters 5 in at least two light source emission modules 1 are of different models, that is, the types of the light beams are different from each other, thereby producing more types of integrated light beams.

[0062] In this embodiment, the light source integration module 2 is used to integrate a plurality of split light beams to form a required light beam.

[0063] In this embodiment, the coagulation detection module 4 is divided into a traditional light detection device and an image analysis device. Since the traditional light detection device cannot detect some special blood types, it needs to cooperate with the image analysis device to perform image analysis detection.

[0064] In this embodiment, the light beam is emitted by the light beam emitter 5, so that the light beam reaches the incident cylinder of the prism 6, and will be refracted to split the light into light beams of different wavelengths, which are emitted through the exit cylinder, and the light beams of different wavelengths will enter the light beam integration module. The light beam integration module will receive the light beams emitted by at least two prisms 6, and these light beams will be superimposed to form an integrated light beam after integration, and will be projected into the blood sample tube 3 through the exit port, and finally pass through the blood sample tube 3. The blood coagulation detection module 4 will perform data analysis by photographing the blood sample tube 3 or receiving the light parameters passing through the blood sample tube 3 to determine whether blood coagulation occurs. Since the prism 6 can split the light beam and can integrate the light of a certain area of ​​the split light beam, the requirements of the light beam emitter 5 are reduced, and the types of integrated light beams are increased. Compared with the traditional method of making different types of light beams, it is simpler and does not require the intervention of multiple devices, which greatly reduces the volume of the detection device and reduces the difficulty of blood coagulation detection in blood samples.

[0065] Optionally, the light source emission module 1 further includes a beam screening plate 7;

[0066] The beam screening plate 7 is placed on the front side of the beam exiting cylindrical surface of the prism 6;

[0067] The beam screening plate 7 is provided with a beam transmission area;

[0068] The beam screening plate 7 is provided with a displacement assembly.

[0069] In this embodiment, a beam screening plate 7 is provided on the exit cylindrical surface of the prism 6, and the movement of the beam screening plate 7 can accurately transmit the required light beam through the beam transmission area. Such a design can block the redundant light beam so that only the selected light beam enters the beam integration module.

[0070] Optionally, the beam integration module includes a pyramid, and the pyramid has at least three conical surfaces;

[0071] The incident area is a cone surface;

[0072] The exit ports are the corresponding vertices of the three cone surfaces.

[0073] In this embodiment, the light beam integration module includes a pyramid, and the screened light beam enters the interior of the pyramid through the cone surface (incident area), and finally converges at the vertex and emits out.

[0074] Optionally, the beam integration module further includes a first rotating motor 8;

[0075] The first rotating motor 8 is provided on the bottom surface of the pyramid.

[0076] In this embodiment, the first rotating motor 8 is installed at the bottom of the pyramid, so that the pyramid can rotate, and the light beam passing through the incident area can be better integrated through the adjustment of the pyramid.

[0077] Optionally, the light source emission module 1 further includes a first condensing lens 9;

[0078] The first condenser lens 9 is located between the light beam emitter 5 and the prism 6 .

[0079] Optionally, the light source emission module 1 further includes a second rotating motor 10;

[0080] The second rotating electrical machine 10 is disposed on the top surface of the prism 6 or on the ground.

[0081] In this embodiment, the light source emission module 1 further includes a first condenser lens 9, which is used to condense the light beam, better project the light beam onto the cylindrical surface of the prism 6, and make the prism 6 split more neatly, so that light beams of different wavelengths will not mix with each other. A second rotating motor 10 is also provided on the top surface or the ground of the prism 6, which enables the splitting of the light beam to be precisely controlled.

[0082] Optionally, the blood coagulation detection device further includes a light-transmitting plate 11, a light-splitting optical fiber 12, and at least two second condensing lenses 13;

[0083] The splitting optical fiber 12 includes an input optical fiber and at least two output optical fibers;

[0084] The input optical fiber is arranged in front of the light-transmitting hole of the light-transmitting plate 11, and the light-transmitting hole of the light-transmitting plate 11 corresponds to the position of the exit port of the beam integration module;

[0085] The second condensing lens 13 is arranged in front of the output optical fiber.

[0086] In this embodiment, in order to increase the rate of coagulation detection, the light integrated by the pyramid is first selected through the light-transmitting holes on the light-transmitting plate 11 to prevent additional light beams from mixing in. At this time, the integrated light beam enters the input optical fiber and is divided into at least two light beams emitted from the output light beam. The light beam is then pipeline-focused by the second focusing lens 13 so that it can be better projected into the blood sample tube 3.

[0087] Optionally, the coagulation detection module 4 includes a filter lens 14 and an optical image analyzer 15;

[0088] The filter lens 14 is disposed between the blood sample tube 3 and the optical image analyzer 15 .

[0089] In this embodiment, in order to prevent the influence of other light beams, a filter lens 14 is provided between the blood sample tube 3 and the optical image analyzer 15. The optical image analyzer 15 can analyze the light beam passing through the blood sample tube 3 and the image of the blood sample tube 3 to obtain an analysis of whether coagulation exists.

[0090] Optionally, the blood coagulation detection device further includes an assembler 16;

[0091] The assembler 16 is provided with a front light incident area, a test tube area and a rear light detection area in sequence;

[0092] The blood sample test tube 3 is arranged in the test tube area;

[0093] The second condenser lens 13 is arranged in the front light incident area;

[0094] The filter lens 14 and the optical image analyzer 15 are arranged in the post-light detection area.

[0095] In this embodiment, the main function of the assembler 16 is to prevent external light beams from affecting the detection, so the second focusing lens 13, the blood sample tube 3, the filter lens 14 and the optical image analyzer 15 are all installed inside the assembler 16, which greatly reduces the influence of external light.

[0096] Optionally, a planar light-transmitting area 17 is provided in the middle of the blood sample tube 3 .

[0097] The side of the traditional test tube is cylindrical, and the light will be refracted when entering, which affects the light transmission to a certain extent. In this embodiment, the side of the blood sample test tube 3 is modified, and a small section of the side is modified into a plane, that is, a plane light-transmitting area 17 is obtained, so that the pipeline can penetrate better during the detection process.

[0098] In the present application, the terms "upper", "lower", "left", "right", "front", "back", "top", "bottom", "inside", "outside", "middle", "vertical", "horizontal", "lateral", "longitudinal" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only used to illustrate the relative positional relationships between the various components or components, and do not particularly limit the specific installation orientations of the various components or components.

[0099] In addition, some of the above terms may be used to express other meanings in addition to indicating orientation or positional relationship. For example, the term "on" may also be used to express a certain dependency or connection relationship in some cases. For those of ordinary skill in the art, the specific meanings of these terms in this application can be understood according to specific circumstances.

[0100] In addition, the terms "installed", "set", "provided with", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection, or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be an internal connection between two devices, elements, or components. For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0101] In addition, the structures, proportions, sizes, etc. drawn in the drawings in the present application are only used to match the contents disclosed in the specification for the technical personnel in this field to understand and read, and are not used to limit the restrictive conditions under which the present application can be implemented. Therefore, they have no substantive technical significance. Any structural modification, change in proportional relationship or adjustment of size should still fall within the scope of the technical content disclosed in the present application without affecting the effects and purposes that can be achieved by the present application.

Claims

1. A blood coagulation detection device for medical samples, characterized in that: include: At least two light source emission modules, a light source integration module, a blood sample tube and a coagulation detection module; The light source emission module includes a light beam emitter and a prism, the light beam emitter is placed perpendicular to the cylindrical surface of the prism, the prism includes at least three cylindrical surfaces, the cylindrical surface of the prism perpendicular to the light beam emitter is the incident cylindrical surface, and the cylindrical surface from which the light beam emerges is the exit cylindrical surface; The beam integration module is provided with at least two incident areas and one exit port, and at least two prisms of the light source emission modules are placed at the rear side of the beam integration module, so that the exit cylindrical surface of each prism corresponds to one of the incident areas of the beam integration module, and the number of the incident areas is greater than or equal to the number of light source emission modules, and the beam integration module is used to integrate the light beams emitted from the exit cylindrical surfaces of the prisms; The blood sample test tube is arranged in front of the exit port of the light beam integration module; The coagulation detection module is located on one side of the blood sample tube.

2. The blood coagulation detection device according to claim 1, characterized in that: The light source emission module also includes a beam screening plate; The beam screening plate is placed on the front side of the beam exiting column of the prism; The beam screening plate is provided with a beam transmission area; The beam screening plate is provided with a displacement assembly.

3. The blood coagulation detection device according to claim 1, characterized in that: The beam integration module includes a pyramid, and the pyramid has at least three cone surfaces; The incident area is a cone surface; The emission ports are corresponding vertices of the three cone surfaces.

4. The blood coagulation detection device according to claim 3, characterized in that: The beam integration module also includes a first rotating motor; The first rotating motor is arranged on the bottom surface of the pyramid.

5. The blood coagulation detection device according to claim 1, characterized in that: The light source emission module also includes a first condensing lens; The first condenser lens is located between the light beam emitter and the prism.

6. The blood coagulation detection device according to claim 1, characterized in that: The light source emission module also includes a second rotating motor; The second rotating motor is arranged on the top surface or the ground of the prism.

7. The blood coagulation detection device according to any one of claims 1 to 6, characterized in that: The blood coagulation detection device also includes a light-transmitting plate, a light-splitting optical fiber, and at least two second condensing lenses; The splitting optical fiber includes an input optical fiber and at least two output optical fibers; The input optical fiber is arranged in front of the light-transmitting hole of the light-transmitting plate, and the light-transmitting hole of the light-transmitting plate corresponds to the position of the exit port of the light beam integration module; The second condensing lens is arranged in front of the output optical fiber.

8. The blood coagulation detection device according to claim 7, characterized in that: The coagulation detection module includes a filter lens and an optical image analyzer; The filter lens is arranged between the blood sample tube and the optical image analyzer.

9. The blood coagulation detection device according to claim 8, characterized in that: The blood coagulation detection device also includes an assembler; The assembler is sequentially provided with a front light incident area, a test tube area and a rear light detection area; The blood sample test tube is arranged in the test tube area; The second condenser lens is arranged at the front light incident area; The filter lens and the optical image analyzer are arranged in the post-light detection area.

10. The blood coagulation detection device according to claims 1 to 6, characterized in that: A plane light-transmitting area is arranged in the middle of the blood sample test tube.

Images