Mild anti-dandruff and deoiling shampoo

Abstract

The invention belongs to the technical field of wash care products, and particularly provides a mild anti-dandruff and deoiling shampoo. The shampoo is prepared from the following raw materials: 13 to 19 percent of cleaning type surfactant, 1.8 to 2.5 percent of glycerol, 1.8 to 2.2 percent of polydimethylsiloxane alcohol, 1.8 to 2.2 percent of coconut oil monoethanolamide, 1.8 to 2 percent of cocamidopropyl betaine, 1.5 to 2 percent of distearyl phthalic amide, 0.8 to 1 percent of selenium disulfide, 0.7 to 1 percent of modified salicylic acid, 0.6 to 0.9 percent of compound plant extract, 0.45 to 0.55 percent of sodium chloride, 0.4 to 0.6 percent of essence and the balance of water. The cleaning agent is prepared from the following components in percentage by weight: 0.4 to 0.5 percent of phenoxyethanol, 0.35 to 0.45 percent of guar gum hydroxypropyl trimethyl ammonium chloride, 0.3 to 0.5 percent of eucalyptus oil, 0.1 to 0.14 percent of sodium hydroxide, 0.81 to 1.16 percent of other trace components and the balance of water. The shampoo provided by the invention can maintain the stability of selenium disulfide, all the components are compatible with one another, hair and scalp can be mildly cleaned, the shampoo is fresh and not greasy, and the effects of deeply removing dandruff and relieving itching are achieved.

Description

Technical Field

[0001] The invention belongs to the technical field of washing and care products, and in particular relates to a mild dandruff and oil-removing shampoo. Background Art

[0002] As people's pace of life accelerates and environmental problems become increasingly severe, scalp health issues are gradually gaining attention. Dandruff and excessive oil secretion are among the most common scalp problems. They not only affect personal image, but may also cause health problems such as scalp inflammation. Although traditional anti-dandruff shampoos have significant anti-dandruff effects, long-term use may affect scalp health, such as dry scalp, allergies and other problems.

[0003] Chinese patent CN 18402968 A discloses a herbal deep anti-dandruff shampoo, which includes the following components: an anti-dandruff agent, a detergent, a plant scalp care solution, a film-forming agent, a fragrance, a thickener, a preservative, a cooling agent, and a solvent. The shampoo provided by this invention can deeply remove scalp dandruff. However, this invention does not introduce a chelating agent or a stabilizer component. After long-term storage, the selenium disulfide in the anti-dandruff agent is very likely to be stratified, which is not conducive to its function.

[0004] Therefore, there is an urgent need for a mild anti-dandruff and oil-removing shampoo that can simultaneously maintain the stability of selenium disulfide in the system. Summary of the invention

[0005] In view of the existing technical problems, the purpose of the present invention is to provide a mild dandruff and oil-removing shampoo. The shampoo provided by the present invention can maintain the stability of selenium disulfide, and the various components are compatible with each other, can gently clean the hair and scalp, and is refreshing and non-greasy, achieving the effects of deep dandruff removal and itching relief.

[0006] In order to achieve the above object, the technical solution adopted by the present invention is as follows:

[0007] The present invention provides a mild anti-dandruff and degreasing shampoo, which comprises the following raw materials by mass percentage: 13-19% of a cleansing surfactant, 1.8-2.5% of glycerol, 1.8-2.2% of dimethiconol, 1.8-2.2% of coconut acid monoethanolamide, 1.8-2% of cocamidopropyl betaine, 1.5-2% of distearyl phthalamide, 0. 8-1%, modified salicylic acid 0.7-1%, compound plant extract 0.6-0.9%, sodium chloride 0.45-0.55%, flavor 0.4-0.6%, phenoxyethanol 0.4-0.5%, guar hydroxypropyltrimonium chloride 0.35-0.45%, eucalyptus oil 0.3-0.5%, sodium hydroxide 0.1-0.14%, other trace ingredients 0.81-1.16%, and the balance is water.

[0008] The reaction mechanism and effects of the present invention are as follows:

[0009] 1. Eucalyptus oil of the present invention has good bactericidal and anti-inflammatory effects, and fragrance can provide a refreshing and refreshing feeling, which helps to improve mental vitality. Eucalyptus globulus leaf oil contains high concentration of eucalyptol, which has powerful antibacterial and anti-inflammatory effects, while the main component of lemon eucalyptus oil is citronellal, which also has antibacterial and insecticidal effects, and eucalyptus leaf oil has antibacterial activity and has therapeutic effects on skin diseases. The applicant unexpectedly found that using the three in the system after compounding can enhance the antibacterial and anti-inflammatory effects of shampoo, has a synergistic effect, helps to clean the scalp, reduces oil accumulation, and removes dandruff. At the same time, eucalyptus essential oil has a high oxygen content, which may have potential therapeutic effects on people such as asthma, influenza, and upper respiratory tract infections. In addition, the present invention adds sodium hydroxide to the distillate to make the polyphenols and free acid substances with bad smell react with the sodium hydroxide during the distillation process to generate new substances such as sodium phenolate or salt, which not only reduces the possible bad smell, but also greatly improves the boiling point, so that in the fractionation and purification process, such substances will not be fractionated out together with the target product, greatly improving the product quality of the extracted eucalyptus oil and reducing material loss.

[0010] 2. Salicylic acid is an active substance derived from nature, which has a significant inhibitory effect on microorganisms such as bacteria and fungi. Salicylic acid can decompose the connecting substances between keratinocytes, promote the shedding of aged stratum corneum, help remove excessively thick keratin, and accelerate the skin's renewal process. However, salicylic acid may cause certain irritation when it comes into direct contact with the skin, which has a potential discomfort effect on the skin. At the same time, due to the poor solubility of salicylic acid in water, it is easy to separate from the solution and recrystallize, which limits its effect in practical applications.

[0011] The present invention uses polyquaternium-7 and cyclodextrin to modify salicylic acid, thereby enhancing the solubility and stability of salicylic acid in water, promoting the improvement of antibacterial effect, and reducing irritation to the skin. At the same time, polyquaternium-7 will electrostatically adsorb with guar hydroxypropyltrimethylammonium chloride in the formula, further promoting the dispersion of salicylic acid.

[0012] 3. The composite plant extract of the present invention is a natural crop, mild, safe and effective, and has synergistic effects in antibacterial, anti-inflammatory, soothing and oil control effects.

[0013] Purslane extract has anti-inflammatory effects, can reduce the secretion of inflammatory factor interleukin, soothe skin inflammation, and inhibit skin itching; at the same time, Purslane extract has an inhibitory effect on hyaluronidase, can inhibit allergic reactions, protect skin cells from ultraviolet damage, and has the function of soothing and repairing the skin barrier.

[0014] Sophora flavescens root extract has antibacterial and anti-inflammatory effects and is known as a "natural anti-inflammatory antibiotic". It can effectively kill bacteria, inhibit bacteria and fight inflammation. Malassezia is the main factor causing seborrheic dermatitis. The antibacterial properties of Sophora flavescens root extract balance the oil secretion, thereby dredging and tightening pores, removing toxins and impurities in the skin, and promoting the growth and repair of damaged blood vessel nerve cells. The applicant has found that the combination of Pelargonium odoratum flower / leaf / stem extract and Sophora flavescens root extract has a synergistic antibacterial effect, especially the antibacterial effect on Malassezia.

[0015] Aloe barbadensis extract has the properties of astringent, softening, moisturizing and anti-inflammatory. It can remove hardening, keratinization, improve scars, keep the scalp moist and tender, and has a care effect on hair, which can keep the hair moist and smooth and prevent hair loss. Field mint leaf extract usually has a cooling effect and can bring a refreshing feeling to the scalp. Golden chamomile extract has anti-inflammatory and soothing effects, which can help reduce scalp inflammation and allergic reactions. It can be seen that the three synergistically improve the comfort of the scalp from multiple angles.

[0016] 4. Selenium disulfide can effectively inhibit the growth of fungi on the scalp, reduce the production of dandruff, and can also deeply clean the scalp and remove excess oil and dirt. However, selenium disulfide is easily oxidized and discolored, and its particle size distribution is uneven and easy to agglomerate. The suspension system formed is very unstable, resulting in product stratification, which in turn affects the product's anti-dandruff effect; at the same time, using lotions containing selenium disulfide can easily make hair tangled, dry, and not smooth.

[0017] The present invention makes selenium disulfide stable and effective by adding multiple auxiliary agents. On the one hand, the introduction of citric acid and ethylhexylglycerol has a chelating effect on the metal ions in selenium disulfide, preventing the shampoo from changing color. On the other hand, by adding coconut acid monoethanolamide and hydrogenated castor oil to synergistically stabilize selenium disulfide, the problem that selenium disulfide shampoo foam is not persistent, and the shampoo is easy to stratify, change color, and precipitate is solved. Then, the applicant introduces a surfactant (such as: sodium laureth sulfate, ammonium lauryl sulfate, cocamidopropyl betaine, sodium methyl cocoyl taurate) to synergistically reduce the surface tension of water, which is conducive to making selenium disulfide uniformly ground during the preparation process, preventing selenium disulfide from agglomerating. In addition, the synergistic effect of coconut acid monoethanolamide and cocamidopropyl betaine can enhance the foam performance of shampoo, provide more abundant foam and better wet hair flushing softness, reduce the generation of static electricity, improve the shampooing experience of consumers, and make the shampoo gentle and non-irritating, and can also play a thickening effect.

[0018] 5. The cleansing surfactant of the present invention is a compound of sodium lauryl polyether sulfate and ammonium lauryl sulfate, which can not only produce dense foam to help clean the grease and dirt on the scalp and hair, but also reduce irritation and achieve a mild effect.

[0019] In some embodiments, the cleansing surfactant is a combination of sodium laureth sulfate and ammonium lauryl sulfate.

[0020] Preferably, the mass ratio of sodium laureth sulfate to ammonium lauryl sulfate is (1.5-1.8):1.

[0021] In some embodiments, the other trace ingredients include the following raw materials: peppermint oil, hydrogenated castor oil, sodium methyl cocoyl taurate, laureth-23, TEA dodecylbenzenesulfonate, lauric acid, laureth-4, PEG-55 stearate, citric acid, pigment, glyceryl laurate, glyceryl caprylate, ethylhexylglycerin, sodium benzoate, butylene glycol, 1,2-hexanediol, and p-hydroxyacetophenone.

[0022] In some embodiments, the composite plant extract is a combination of Portulaca oleracea extract, golden chamomile extract, Pelargonium graveolens flower / leaf / stem extract, mint leaf extract, Aloe vera extract and Sophora flavescens root extract.

[0023] Preferably, the mass ratio of the purslane extract, the sophora flavescens root extract, the golden chamomile extract, the pelargonium graveolens flower / leaf / stem extract, the mint leaf extract and the aloe vera extract is (1-1.5):(1-1.2):1:1:1:(1-1.2).

[0024] In some embodiments, the method for preparing eucalyptus oil comprises the following steps:

[0025] Q1. Take fresh eucalyptus leaves, lemon eucalyptus leaves and eucalyptus leaves, wash, dry and crush them to obtain eucalyptus leaf powder, lemon eucalyptus leaf powder and eucalyptus leaf powder;

[0026] Q2. The eucalyptus globulus leaf powder, lemon eucalyptus leaf powder and eucalyptus eucalyptus leaf powder obtained in step Q1 were mixed with distilled water at a solid-liquid ratio of 1 g: (2-3.5) mL, treated at 6000-9000 r / min for 8-15 min, ultrasonically treated, and then distilled water was added to adjust the solid-liquid ratio to 1 g: (5-8) mL to obtain a eucalyptus slurry;

[0027] Q3. The eucalyptus slurry obtained in step Q2 is distilled for 2-3 hours, and the oil and water are separated after condensation to obtain eucalyptus crude oil;

[0028] Q4. The crude eucalyptus oil obtained in step Q3 and an aqueous sodium hydroxide solution are mixed and distilled, the fractions are collected, and dried over anhydrous sodium sulfate to obtain eucalyptus oil.

[0029] In some embodiments, the conditions of the ultrasonic treatment in step Q2 are: ultrasonic power 200-350W, ultrasonic time 15-30min.

[0030] In some embodiments, the mass ratio of the eucalyptus globulus leaf powder, the eucalyptus lemon leaf powder and the eucalyptus eucalyptus leaf powder in step Q2 is 1:(0.4-0.7):(0.6-0.9).

[0031] In some embodiments, the mass ratio of the eucalyptus crude oil to the sodium hydroxide in the sodium hydroxide aqueous solution in step Q4 is 100:(0.4-0.8).

[0032] In some embodiments, the method for preparing the modified salicylic acid comprises the following steps:

[0033] T1. Dissolve salicylic acid in anhydrous ethanol to obtain a solution; dissolve polyquaternium-7 and cyclodextrin in deionized water, stir for 24-48h, and dry to obtain a solid;

[0034] T2. The solution obtained in step T1 is mixed with the solid, stirred at 50-70°C for 15-20h, ground, poured into a reaction kettle, reacted at 120-160°C for 3-5h, cooled, washed, and dried to obtain modified salicylic acid.

[0035] In some embodiments, the mass ratio of salicylic acid to solid in the solution in step T2 is (0.05-0.2):1.

[0036] Preferably, the mass ratio of polyquaternium-7 to cyclodextrin in step T1 is (1-2):1.

[0037] Compared with the prior art, the present invention has the following beneficial effects:

[0038] 1. The shampoo provided by the present invention can maintain the stability of selenium disulfide, and the various components are compatible with each other, can gently clean the hair and scalp, is refreshing and non-greasy, and achieves the effects of deep dandruff removal and itching relief.

[0039] 2. The eucalyptus oil of the present invention has good bactericidal and anti-inflammatory effects, and the fragrance can provide a refreshing and invigorating feeling, which helps to improve mental vitality. The applicant not only improved the product quality of the extracted eucalyptus oil, but also unexpectedly found that the combination of the three can enhance the antibacterial and anti-inflammatory effects of shampoo, has a synergistic effect, helps to clean the scalp, reduce oil accumulation, and remove dandruff.

[0040] 3. The modified salicylic acid synthesized by the present invention enhances the solubility and stability of salicylic acid in water, promotes the improvement of antibacterial effect, and reduces irritation to the skin.

[0041] 4. The composite plant extract of the present invention is a natural crop, mild, safe and effective, and has synergistic effects in antibacterial, anti-inflammatory, soothing and oil control effects.

[0042] 5. The present invention adds a variety of additives to ensure that selenium disulfide can exert its efficacy stably, thereby avoiding stratification and discoloration of selenium disulfide and improving the user experience of customers. DETAILED DESCRIPTION

[0043] The present invention will be described below in conjunction with specific embodiments. It should be noted that the following embodiments are examples of the present invention and are only used to illustrate the present invention, rather than to limit the present invention. Other combinations and various modifications within the concept of the present invention may be performed without departing from the spirit or scope of the present invention.

[0044] According to the ratios of the raw materials and the preparation methods specified in the following examples and comparative examples, various shampoos were prepared.

[0045] In order to facilitate those skilled in the art to implement the present invention, some raw material manufacturers of the embodiments and comparative examples are described as follows:

[0046] Polydimethylsiloxane alcohol: purchased from Hubei Shineng Chemical Technology Co., Ltd., model number DC-1501;

[0047] Laureth-23 and Laureth-4: purchased from Haian Petrochemical Plant, Jiangsu Province;

[0048] PEG-55 stearate: purchased from Tianjin Xiensi Biochemical Technology Co., Ltd.;

[0049] Polyquaternium-7: purchased from Jinan Henghan Chemical Co., Ltd.

[0050] Cyclodextrin: purchased from Xi'an Jinxiang Pharmaceutical Excipients Co., Ltd.

[0051] Other raw materials are not specially specified and can be purchased from the market.

[0052] Preparation Example 1

[0053] The preparation method of eucalyptus oil A comprises the following steps:

[0054] Q1. Take fresh eucalyptus globulus leaves, lemon eucalyptus leaves and eucalyptus eucalyptus leaves, wash each with deionized water, dry to constant weight at 80°C, and grind through a 100-mesh sieve to obtain eucalyptus globulus leaf powder, lemon eucalyptus leaf powder and eucalyptus eucalyptus leaf powder;

[0055] Q2. 500 g of eucalyptus globulus leaf powder, 275 g of lemon eucalyptus leaf powder and 375 g of eucalyptus eucalyptus leaf powder obtained in step Q1 were mixed with 3000 mL of distilled water, treated with a high-speed tissue crusher at 8000 r / min for 10 min, 300 W ultrasonic treatment for 20 min, and then 4800 mL of distilled water was added to obtain a eucalyptus slurry;

[0056] Q3. The eucalyptus slurry obtained in step Q2 was distilled for 2.5 hours, and the oil and water were separated after condensation to obtain eucalyptus crude oil;

[0057] Q4. A sodium hydroxide solution having a mass concentration of 40% was prepared by mixing sodium hydroxide having a mass concentration of 0.6% of the mass of the crude eucalyptus oil, and the crude eucalyptus oil obtained in step Q3 and the sodium hydroxide solution were mixed and distilled for 4 hours, and the fraction at 170-180° C. was collected and dried with anhydrous sodium sulfate for 24 hours to obtain eucalyptus oil A.

[0058] Preparation Example 2

[0059] The preparation method of eucalyptus oil B is the same as that of Preparation Example 1, except that in step Q2, 500 g of eucalyptus globulus leaf powder, 400 g of lemon eucalyptus leaf powder and 375 g of eucalyptus eucalyptus leaf powder obtained in step Q1 are mixed with 3000 mL of distilled water, processed with a high-speed tissue crusher at 8000 r / min for 10 min, ultrasonically treated at 300 W for 20 min, and then 4800 mL of distilled water are added to obtain a eucalyptus slurry.

[0060] Preparation Example 3

[0061] The preparation method of eucalyptus oil C is the same as that of Preparation Example 1, except that in step Q2, 1200 g of eucalyptus globulus leaf powder obtained in step Q1 is mixed with 3000 mL of distilled water, treated with a high-speed tissue crusher at 8000 r / min for 10 min, ultrasonically treated at 300 W for 20 min, and then 4800 mL of distilled water is added to obtain a eucalyptus leaf slurry.

[0062] Preparation Example 4

[0063] The preparation method of eucalyptus oil D is the same as that of Preparation Example 1, except that in step Q4: sodium hydroxide having a mass percentage of 0.3% of the mass of the crude eucalyptus oil is prepared into a sodium hydroxide aqueous solution having a mass concentration of 40%.

[0064] Preparation Example 5

[0065] The preparation method of modified salicylic acid A comprises the following steps:

[0066] T1. Dissolve 100 g of salicylic acid in 1600 mL of anhydrous ethanol to obtain a solution; dissolve 150 g of polyquaternium-7 and 100 g of cyclodextrin in 1000 mL of deionized water, stir for 36 h, and dry at 80 ° C to constant weight to obtain a solid;

[0067] T2. Mix 240 mL of the solution obtained in step T1 and 100 g of the solid, stir at 60 ° C for 18 h, dry at 75 ° C for 2 h, grind, pour into a sealed pressure bottle, react at 150 ° C for 4 h, cool to room temperature, wash with deionized water 3 times, and dry at 85 ° C to constant weight to obtain modified salicylic acid A.

[0068] Preparation Example 6

[0069] The preparation method of modified salicylic acid B is the same as that of Preparation Example 5, except that 48 mL of solution is added in step T2.

[0070] Example 1

[0071] A mild anti-dandruff and degreasing shampoo comprises the following raw materials, calculated by mass percentage of 100%, including 16% of a cleansing surfactant, 2.2% of glycerol, 2% of dimethicone, 2% of cocoyl monoethanolamide, 1.9% of cocamidopropyl betaine, 1.7% of distearyl phthalamide, 0.9% of selenium disulfide, 0.85% of modified salicylic acid A, 0.75% of a composite plant extract, 0.5% of sodium chloride, 0.5% of orange essence, 0.45% of phenoxyethanol, 0.4% of guar hydroxypropyltrimonium chloride, 0.4% of eucalyptus oil A, 0.12% of sodium hydroxide, 0.1% of peppermint oil, 0.1% of hydrogenated castor oil, 0.1% of sodium methyl cocoyl taurate, and 0.1% of laureth-23. 0.07%, TEA dodecylbenzenesulfonate 0.07%, lauric acid 0.07%, laureth-4 0.07%, PEG-55 stearate 0.07%, citric acid 0.05%, pigment 0.045%, glyceryl laurate 0.045%, glyceryl caprylate 0.045%, ethylhexylglycerin 0.045%, sodium benzoate 0.03%, butylene glycol 0.03%, 1,2-hexanediol 0.03%, p-hydroxyacetophenone 0.015%, the balance is water;

[0072] The cleaning surfactant includes sodium laureth sulfate and ammonium lauryl sulfate, and the mass ratio of the two is 1.65:1;

[0073] The composite plant extract comprises purslane extract, golden chamomile extract, geranium flower / leaf / stem extract, mint leaf extract, aloe vera extract and sophora flavescens root extract, and the mass ratio of the six is ​​1.25:1.1:1:1:1:1.1;

[0074] The pigment contains a mixture of CI 19140 and CI 42090 in a mass ratio of 1:1.

[0075] The preparation method of the shampoo of this embodiment comprises the following steps:

[0076] Add water to the cleaned and disinfected emulsifying pot, add a cleaning surfactant, disperse evenly, start heating to 80°C, add guar hydroxypropyltrimonium chloride, cocoyl monoethanolamide, cocamidopropyl betaine, distearyl phthalamide, keep warm for 30 minutes, cool to 30°C, add glycerin, dimethicone, selenium disulfide, modified salicylic acid A, complex plant extract, sodium chloride, orange essence, phenoxyethanol, eucalyptus oil A, sodium hydroxide, peppermint oil, hydrogenated castor oil, sodium methyl cocoyl taurate, laureth-23, TEA dodecylbenzenesulfonate, lauric acid, laureth-4, PEG-55 stearate, citric acid, pigment, glyceryl laurate, glyceryl caprylate, ethylhexylglycerin, sodium benzoate, butylene glycol, 1,2-hexanediol, and p-hydroxyacetophenone, stir evenly, pass the inspection, fill and package to obtain shampoo.

[0077] Example 2

[0078] A mild anti-dandruff and degreasing shampoo comprises the following raw materials, calculated by mass percentage of 100%, including 13% of a cleansing surfactant, 1.8% of glycerin, 1.8% of dimethicone, 1.8% of cocoyl monoethanolamide, 1.8% of cocamidopropyl betaine, 1.5% of distearyl phthalamide, 0.8% of selenium disulfide, 0.7% of modified salicylic acid A, 0.6% of a composite plant extract, 0.45% of sodium chloride, 0.4% of orange essence, 0.4% of phenoxyethanol, 0.35% of guar hydroxypropyltrimonium chloride, 0.3% of eucalyptus oil A, 0.1% of sodium hydroxide, 0.08% of peppermint oil, 0.08% of hydrogenated castor oil, 0.08% of sodium methyl cocoyl taurate, and 0.08% of laureth-23. 0.06%, TEA dodecylbenzenesulfonate 0.06%, lauric acid 0.06%, laureth-4 0.06%, PEG-55 stearate 0.06%, citric acid 0.04%, pigment 0.04%, glyceryl laurate 0.04%, glyceryl caprylate 0.04%, ethylhexylglycerin 0.04%, sodium benzoate 0.02%, butylene glycol 0.02%, 1,2-hexanediol 0.02%, p-hydroxyacetophenone 0.01%, the balance is water;

[0079] The cleaning surfactant includes sodium laureth sulfate and ammonium lauryl sulfate, and the mass ratio of the two is 1.5:1;

[0080] The composite plant extract comprises purslane extract, golden chamomile extract, geranium flower / leaf / stem extract, mint leaf extract, aloe vera extract and sophora flavescens root extract, and the mass ratio of the six is ​​1:1:1:1:1:1:1;

[0081] The pigment contains a mixture of CI 19140 and CI 42090 in a mass ratio of 1:1.

[0082] The preparation method of the shampoo of this embodiment is the same as that of Example 1.

[0083] Example 3

[0084] A mild anti-dandruff and degreasing shampoo comprises the following raw materials, calculated by mass percentage of 100%, including 19% of a cleansing surfactant, 2.5% of glycerin, 2.2% of dimethicone, 2.2% of cocoyl monoethanolamide, 2% of cocamidopropyl betaine, 2% of distearyl phthalamide, 1% of selenium disulfide, 1% of modified salicylic acid A, 0.9% of a composite plant extract, 0.55% of sodium chloride, 0.6% of orange essence, 0.5% of phenoxyethanol, 0.45% of guar hydroxypropyltrimonium chloride, 0.5% of eucalyptus oil A, 0.14% of sodium hydroxide, 0.12% of peppermint oil, 0.12% of hydrogenated castor oil, 0.12% of sodium methyl cocoyl taurate, and 0.12% of laureth-23. 0.08%, TEA dodecylbenzenesulfonate 0.08%, lauric acid 0.08%, laureth-4 0.08%, PEG-55 stearate 0.08%, citric acid 0.06%, pigment 0.05%, glyceryl laurate 0.05%, glyceryl caprylate 0.05%, ethylhexylglycerin 0.05%, sodium benzoate 0.04%, butylene glycol 0.04%, 1,2-hexanediol 0.04%, p-hydroxyacetophenone 0.02%, the balance is water;

[0085] The cleaning surfactant includes sodium laureth sulfate and ammonium lauryl sulfate, and the mass ratio of the two is 1.8:1;

[0086] The composite plant extract comprises purslane extract, golden chamomile extract, geranium flower / leaf / stem extract, mint leaf extract, aloe vera extract and sophora flavescens root extract, and the mass ratio of the six is ​​1.5:1.2:1:1:1:1.2;

[0087] The pigment contains a mixture of CI 19140 and CI 42090 in a mass ratio of 1:1.

[0088] The preparation method of the shampoo of this embodiment is the same as that of Example 1.

[0089] Example 4

[0090] A mild anti-dandruff and degreasing shampoo, the specific implementation manner is the same as that of Example 1, except that an equal amount of eucalyptus oil B is used instead of eucalyptus oil A.

[0091] Example 5

[0092] A mild anti-dandruff and degreasing shampoo, the specific implementation manner is the same as that of Example 1, except that an equal amount of eucalyptus oil C is used instead of eucalyptus oil A.

[0093] Example 6

[0094] A mild anti-dandruff and degreasing shampoo, the specific implementation manner is the same as that of Example 1, except that an equal amount of eucalyptus oil D is used instead of eucalyptus oil A.

[0095] Example 7

[0096] A mild anti-dandruff and degreasing shampoo, the specific implementation manner is the same as that of Example 1, except that an equal amount of modified salicylic acid B is used to replace modified salicylic acid A.

[0097] Example 8

[0098] A mild anti-dandruff and degreasing shampoo, the specific implementation manner is the same as that of Example 1, except that the composite plant extract comprises a purslane extract and an aloe vera extract in a mass ratio of 1:1.

[0099] Comparative Example 1

[0100] A mild anti-dandruff and degreasing shampoo, the specific implementation manner is the same as that of Example 1, except that an equal amount of commercially available eucalyptus globulus leaf oil is used instead of eucalyptus oil A.

[0101] Comparative Example 2

[0102] A mild anti-dandruff and degreasing shampoo, the specific implementation manner is the same as that of Example 1, except that an equal amount of commercially available salicylic acid is used to replace modified salicylic acid A.

[0103] Comparative Example 3

[0104] A mild anti-dandruff and degreasing shampoo, the specific implementation manner is the same as that of Example 1, except that citric acid and coconut oil monoethanolamide are not added.

[0105] Effect evaluation:

[0106] The shampoos prepared in the above Examples 1-8 and Comparative Examples 1-3 were tested and analyzed, and the specific results are shown in Tables 1-3.

[0107] Performance Testing:

[0108] (1) Anti-dandruff test:

[0109] Principle: Dandruff is a desquamation phenomenon caused by excessive proliferation of keratinocytes of the scalp, and the main cause of excessive proliferation of keratinocytes of the scalp is the excessive proliferation of Malassezia in the scalp. Studies have shown that the symptoms of excessive dandruff will improve with the reduction of the level of Malassezia, and relapse with the increase of the amount of bacteria, which has a correlation. The shampoos prepared in the above Examples 1-8 and Comparative Examples 1-3 were subjected to antibacterial tests, and the results are shown in Table 1.

[0110] Steps: 1) Dilute the Malassezia suspension appropriately with PBS solution. The required concentration is: take 0.1 mL and drop it into 5.0 mL of control sample solution (PBS). The number of recovered bacteria is 1×10 4 CFU / mL-9x10 4 CFU / mL; 2) Pipette 5.0mL of the original solution of the test sample into a sterile test tube; 3) Pipette 0.1mL of the test bacterial solution into a test tube containing 5.0mL of the sample, mix quickly, and start timing immediately; 4) After 10 minutes, take 0.5mL of the mixed solution of the test bacteria and the sample, add it to a test tube containing 4.5mL of sterilized PBS, and mix thoroughly; 5) Pipette 1mL of the sample solution (3 dilutions) and place it in a sterile plate, inoculate two sterile plates for each dilution, pour 15mL of the modified Leeming-Notman medium cooled to 45℃, rotate the plate to make it fully uniform, turn the plate over after the agar solidifies, and culture at 30℃ for 72h, and then count the live bacterial colonies; 6) Replace the test sample with PBS and follow the above steps as the control group; 7) Repeat the test 3 times and calculate the average value.

[0111] Calculation method: The antibacterial rate is calculated according to the formula, and the result is expressed as a percentage (%), with 2 decimal places reserved:

[0112] Bacterial inhibition rate % = (I-II) / I × 100%, where:

[0113] I--average colony count of control samples, in colony forming units per milliliter (CFU / mL);

[0114] Ⅱ--Average colony count of the test sample, in colony forming units per milliliter (CFU / mL).

[0115] Table 1

[0116] Serial number Antibacterial rate / % Example 1 99.5 Example 2 99.4 Example 3 99.6 Example 4 96.5 Example 5 94.4 Example 6 95.2 Example 7 89.8 Example 8 91.1 Comparative Example 1 90.5 Comparative Example 2 85.3 Comparative Example 3 97.5

[0117] From the results in Table 1, it can be seen that the shampoos of Examples 1-3 have good antibacterial rates and good anti-dandruff effects.

[0118] Compared with Example 1, when preparing eucalyptus oil, Example 4 changes the mass ratio of eucalyptus globulus leaf powder, lemon eucalyptus leaf powder and eucalyptus eucalyptus leaf powder, and the antibacterial and anti-inflammatory effects are reduced. Example 5 only uses eucalyptus globulus leaf powder, and the synergistic effect is lost. Example 6 changes the mass ratio of eucalyptus crude oil and sodium hydroxide in sodium hydroxide aqueous solution, which reduces the product quality of eucalyptus oil, thereby reducing the antibacterial rate and affecting the anti-dandruff effect.

[0119] Compared with Example 1, in Example 7, the mass ratio of salicylic acid to solid in the solution was changed when preparing the modified salicylic acid, which reduced the antibacterial effect and further reduced the anti-dandruff effect.

[0120] Compared with Example 1, Example 8 changed the type of composite plant extract, which reduced the antibacterial effect and further reduced the anti-dandruff effect.

[0121] Compared with Example 1, Comparative Example 1 and Comparative Example 2 replace eucalyptus oil A with an equal amount of commercially available eucalyptus globulus leaf oil, and the bactericidal and anti-inflammatory effects are significantly reduced. Comparative Example 2 replaces modified salicylic acid A with an equal amount of commercially available salicylic acid, and salicylic acid has poor water solubility. Comparative Example 3 does not add citric acid and coconut oil monoethanolamide, which makes the product stability poor, and then the antibacterial rate will be reduced. Among them, Comparative Example 3 only slightly affects the anti-dandruff effect because the product has not been placed for a long time.

[0122] (2) Stability test: The shampoos prepared in Examples 1-3 and Comparative Example 3 were placed at 25°C, 45°C and -15°C for 4 months respectively. The properties of the samples under various conditions before and after storage were examined. The results are shown in Table 2.

[0123] Table 2

[0124] Serial number 25℃ 45℃ -15℃ Example 1 No delamination, no obvious discoloration No delamination, no obvious discoloration No delamination, no obvious discoloration Example 2 No delamination, no obvious discoloration No delamination, no obvious discoloration No delamination, no obvious discoloration Example 3 No delamination, no obvious discoloration No delamination, no obvious discoloration No delamination, no obvious discoloration Comparative Example 3 Slight discoloration due to delamination Obvious discoloration Obvious discoloration

[0125] (3) Mildness test: Select qualified patch test equipment and use the closed patch test method to place about 0.020 mL to 0.025 mL of the test substance (the shampoo prepared in Examples 1-3 above) in the patch tester, which is fixed on the inner side of the subject's forearm. Remove the test substance after 24 hours, and observe the skin reaction 0.5 hours, 24 hours, and 48 hours after removal. The number of subjects in each group is 10 people who meet the health test standards, and the results are recorded according to the skin reaction grading standards in the "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0126] After testing, no allergic reaction was found among the 30 test subjects, indicating that the shampoo product of the present invention is mild.

[0127] (4) Satisfaction test:

[0128] 200 volunteers with dandruff and oily hair were divided into 5 groups, 40 people in each group, and used the test sample shampoo (Examples 1-3 and Comparative Examples 1-2) twice a week for 4 consecutive weeks. The safety and anti-dandruff and oil-removing efficacy were evaluated through the volunteers' experience. Anti-dandruff and oil-removing efficacy standards: a. Very effective: The anti-dandruff and oil-removing effect is very good, the foam is delicate and full, and the hair is refreshed and not tight after washing; b. Effective: There is a certain anti-dandruff and oil-removing effect, the foam is easier to rinse, and the hair is not dry after washing; c. Ineffective: There is no change before and after use, and the results are shown in Table 3.

[0129] Table 3

[0130]

[0131]

[0132] It can be seen that the shampoos prepared in Examples 1-3 of the present invention have a higher satisfaction rate, while the shampoos prepared in Comparative Examples 1-2 have a lower satisfaction rate.

[0133] In summary, the shampoos prepared in Examples 1-3 can maintain the stability of selenium disulfide, and the ingredients are compatible with each other, can gently clean the hair and scalp, are refreshing and non-greasy, achieve deep dandruff removal and antipruritic effects, and have high customer satisfaction.

[0134] The above is only a preferred embodiment of the present invention and does not constitute any form of limitation to the present application. Although the present application is disclosed as above in the preferred embodiment, it is not intended to limit the present application. Any technician familiar with the profession, without departing from the scope of the technical solution of the present application, using the technical content disclosed above to make slight changes or modifications are equivalent to equivalent implementation cases. However, any simple modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution.

Claims

1. A mild anti-dandruff and degreasing shampoo, characterized in that: The shampoo comprises the following raw materials, calculated by mass percentage of 100%, 13-19% of cleansing surfactant, 1.8-2.5% of glycerol, 1.8-2.2% of dimethicone alcohol, 1.8-2.2% of cocoyl monoethanolamide, 1.8-2% of cocamidopropyl betaine, 1.5-2% of distearyl phthalamide, 0.8-1% of selenium disulfide, 0.7-1% of modified salicylic acid, 0.6-0.9% of composite plant extract, 0.45-0.55% of sodium chloride, 0.4-0.6% of flavor, 0.4-0.5% of phenoxyethanol, 0.35-0.45% of guar hydroxypropyltrimethylammonium chloride, 0.3-0.5% of eucalyptus oil, 0.1-0.14% of sodium hydroxide, 0.81-1.16% of other trace ingredients, and the balance is water.

2. A mild anti-dandruff and degreasing shampoo according to claim 1, characterized in that: The cleansing surfactant is a composition of sodium laureth sulfate and ammonium lauryl sulfate.

3. A mild anti-dandruff and degreasing shampoo according to claim 1, characterized in that: The other trace ingredients include the following raw materials: peppermint oil, hydrogenated castor oil, sodium methyl cocoyl taurate, laureth-23, TEA dodecylbenzenesulfonate, lauric acid, laureth-4, PEG-55 stearate, citric acid, pigment, glyceryl laurate, glyceryl caprylate, ethylhexylglycerin, sodium benzoate, butylene glycol, 1,2-hexanediol, and p-hydroxyacetophenone.

4. A mild anti-dandruff and degreasing shampoo according to claim 1, wherein the composite plant extract is a combination of purslane extract, golden chamomile extract, geranium flower / leaf / stem extract, field mint leaf extract, aloe vera extract and sophora flavescens root extract.

5. A mild anti-dandruff and degreasing shampoo according to claim 1, characterized in that: The preparation method of the eucalyptus oil comprises the following steps: Q1. Take fresh eucalyptus leaves, lemon eucalyptus leaves and eucalyptus leaves, wash, dry and crush them to obtain eucalyptus leaf powder, lemon eucalyptus leaf powder and eucalyptus leaf powder; Q2. The eucalyptus globulus leaf powder, lemon eucalyptus leaf powder and eucalyptus eucalyptus leaf powder obtained in step Q1 were mixed with distilled water at a solid-liquid ratio of 1 g: (2-3.5) mL, treated at 6000-9000 r / min for 8-15 min, ultrasonically treated, and then distilled water was added to adjust the solid-liquid ratio to 1 g: (5-8) mL to obtain a eucalyptus slurry; Q3. The eucalyptus slurry obtained in step Q2 is distilled for 2-3 hours, and the oil and water are separated after condensation to obtain eucalyptus crude oil; Q4. The crude eucalyptus oil obtained in step Q3 and an aqueous sodium hydroxide solution are mixed and distilled, the fractions are collected, and dried over anhydrous sodium sulfate to obtain eucalyptus oil.

6. A mild anti-dandruff and degreasing shampoo according to claim 5, characterized in that: The conditions of the ultrasonic treatment in step Q2 are: ultrasonic power 200-350W, ultrasonic time 15-30min.

7. A mild anti-dandruff and degreasing shampoo according to claim 5, characterized in that: The mass ratio of the eucalyptus globulus leaf powder, the eucalyptus lemon leaf powder and the eucalyptus eucalyptus leaf powder in step Q2 is 1:(0.4-0.7):(0.6-0.9).

8. A mild anti-dandruff and degreasing shampoo according to claim 5, characterized in that: The mass ratio of the eucalyptus crude oil to the sodium hydroxide in the sodium hydroxide aqueous solution in step Q4 is 100:(0.4-0.8).

9. A mild anti-dandruff and degreasing shampoo according to claim 1, characterized in that: The preparation method of the modified salicylic acid comprises the following steps: T1. Dissolve salicylic acid in anhydrous ethanol to obtain a solution; dissolve polyquaternium-7 and cyclodextrin in deionized water, stir for 24-48h, and dry to obtain a solid; T2. The solution obtained in step T1 is mixed with the solid, stirred at 50-70°C for 15-20h, ground, poured into a reaction kettle, reacted at 120-160°C for 3-5h, cooled, washed, and dried to obtain modified salicylic acid.

10. A mild anti-dandruff and degreasing shampoo according to claim 9, characterized in that: The mass ratio of salicylic acid to solid in the solution in step T2 is (0.05-0.2):1.

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