Perfusion laser balloon catheter and perfusion laser balloon catheter system

Abstract

The invention discloses a perfusion laser balloon catheter and a balloon catheter system, the perfusion laser balloon catheter is provided with a far end and a near end which are opposite to each other, and the perfusion laser balloon catheter comprises a guide wire and a balloon catheter, the inner tube is fixedly arranged on the periphery of the guide wire in a sleeving mode, the far end of the inner tube is blocked by the blocking piece, the inner tube is provided with a medicine channel, and a first outlet communicated with the medicine channel is formed in the far end of the inner tube; the optical fiber extends along the inner tube, and the far-end part of the inner tube is provided with a light-emitting section; the balloon body is located on the periphery of the inner tube, and the far end of the balloon body is connected with the outer wall of the inner tube in a sealed mode; the first outer tube is located on the periphery of the inner tube and communicated with the near-end side of the balloon body, and a radial gap between the first outer tube and the inner tube serves as a fluid channel for inflating the balloon body. According to the perfusion laser balloon catheter, medicine can be better released, the uniformity of light emission is guaranteed, and therefore the treatment effect on vascular diseases is improved.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a perfusion laser balloon catheter and a perfusion laser balloon catheter. Background Art

[0002] Vascular diseases have become a major cause of disease that affects human health. Vascular interventional surgery can effectively diagnose and treat vascular diseases and is the main treatment for such diseases. As a vascular interventional medical device, the balloon catheter can expand the narrow opening or channel of the blood vessel. The fiber optic balloon catheter is a balloon catheter with an optical fiber as a tube power device. It can be used for phototherapy or to promote drug therapy, thereby achieving the treatment of vascular diseases such as vascular stenosis and occlusion.

[0003] At present, drug-loaded fiber optic balloon catheters usually load drugs on the surface of the balloon, and the balloon expands to contact the blood vessel wall, so that the drugs on the balloon surface are quickly released and transferred to the local blood vessel wall, and the optical fiber emits light of a specific wavelength, which passes through the catheter and the balloon to act on the blood vessel, repairing the blood vessel or causing the drug to form a vascular microstent on the blood vessel wall. This type of balloon catheter can have a certain therapeutic effect, but there are problems such as uneven light emission in the balloon, incomplete drug release, and a lot of residue, which leads to poor treatment effects on vascular diseases. Summary of the invention

[0004] In view of the problems in the prior art, the present application provides a perfusion laser balloon catheter and a perfusion laser balloon catheter system to improve the treatment effect of vascular diseases.

[0005] The perfusion laser balloon catheter provided in the present application has a distal end and a proximal end relative to each other, and the perfusion laser balloon catheter comprises:

[0006] A guide wire having an occluding member fixed at a distal portion thereof;

[0007] An inner tube, fixedly sleeved on the outer periphery of the guide wire, and the distal end of the inner tube is blocked by the blocking member, the inner tube has a drug channel, and the distal end of the inner tube is provided with a first outlet connected to the drug channel;

[0008] An optical fiber extends along the inner tube, wherein the optical fiber has a light-emitting segment at a distal end of the inner tube;

[0009] A balloon body is disposed on the outer periphery of the inner tube, and a distal end of the balloon body is sealed and connected to the outer wall of the inner tube;

[0010] The first outer tube is located at the outer periphery of the inner tube and is communicated with the proximal end of the balloon body. The radial gap between the first outer tube and the inner tube serves as a fluid channel for inflating the balloon body.

[0011] Several optional methods are also provided below, but they are not intended to be additional limitations on the above-mentioned overall solution, but are merely further supplements or preferences. Under the premise that there are no technical or logical contradictions, each optional method can be combined with the above-mentioned overall solution separately, and multiple optional methods can also be combined.

[0012] Optionally, the perfusion laser balloon catheter also includes a tail seat, and the proximal ends of the inner tube, the optical fiber and the first outer tube are all connected to the tail seat, and the tail seat is provided with a first interface connected to the drug channel, a second interface connected to the fluid channel and an optical path interface corresponding to the optical fiber, and the proximal end of the guide wire extends and is connected to the tail seat.

[0013] Optionally, the optical fiber extends along the interior of the inner tube and is fixed to the inner wall of the inner tube.

[0014] Optionally, the tube wall of the inner tube has a first installation channel, and the optical fiber extends along the first installation channel.

[0015] Optionally, the guide wire comprises a body section and a guide section respectively connected to two ends of the blocking member, and the guide section extends out of the distal end of the inner tube;

[0016] The length of the guide section extending out of the distal end of the inner tube is 3 to 5 cm.

[0017] Optionally, the optical fiber extends along the outside of the inner tube and is fixed to the outer wall of the inner tube, and the perfusion laser balloon catheter also includes a second outer tube, and the second outer tube is provided with a second outlet connected to the drug channel.

[0018] Optionally, the inner wall of the second outer tube is provided with a second installation channel, and the optical fiber extends along the second installation channel.

[0019] Optionally, a sealant is poured into a radial gap between the second outer tube and the inner tube, and the optical fiber is buried in the sealant.

[0020] Optionally, the sealant has an intermediate channel connecting the first outlet and the second outlet.

[0021] The present application also provides a perfusion laser balloon catheter system, comprising:

[0022] A perfusion laser balloon catheter, using the perfusion laser balloon catheter;

[0023] a drug delivery device for supplying a fluid containing a drug to the drug passage;

[0024] a filling device, for supplying fluid to the fluid channel to inflate the balloon body;

[0025] A light source device is used to connect with the optical fiber light path.

[0026] Compared with the prior art, the perfusion laser balloon catheter provided in the present application has good luminous uniformity, simple drug release, and is not prone to drug residue, which can effectively improve the therapeutic effect on vascular diseases. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a schematic diagram of the structure of a perfusion laser balloon catheter in one embodiment of the present application;

[0028] Figure 2 A schematic diagram of the partial structure of a perfusion laser balloon catheter in one embodiment;

[0029] Figure 3 This is a schematic diagram of the distal structure of the perfusion laser balloon catheter in one embodiment;

[0030] Figure 4 It is a schematic diagram of the distal structure of the perfusion laser balloon catheter in another embodiment;

[0031] Figure 5 is a schematic diagram of the structure of an inner tube and an optical fiber in one embodiment;

[0032] Figure 6 is a schematic diagram of the structure of an inner tube and an optical fiber in another embodiment;

[0033] Figure 7 This is a schematic diagram of the structure of an inner tube, an optical fiber and a second outer tube in one embodiment;

[0034] Figure 8 This is a schematic diagram of the structure of an inner tube, an optical fiber, a sealant, and a second outer tube in one embodiment;

[0035] Fig. 9 This is a schematic diagram of the structure of a perfusion laser balloon catheter in one embodiment;

[0036] Fig.10 This is a schematic diagram of the structure of a composite section in an embodiment;

[0037] Fig.11 is a schematic structural diagram of a composite section in another embodiment;

[0038] Fig.12 The present invention is a flow chart of a method for processing a perfusion laser balloon catheter in one embodiment.

[0039] The reference numerals in the figures are described as follows:

[0040] 100, perfusion laser balloon catheter; 110, guide wire; 111, body section; 112, plugging piece; 113, guide section; 120, inner tube; 121, drug channel; 122, first outlet; 123, first installation channel; 130, optical fiber; 131, light-emitting section; 140, balloon body; 150, first outer tube; 151, fluid channel; 160, second outer tube; 161, second installation channel; 162, second outlet; 170, sealant; 171, middle channel; 180, developing ring; 190, tailstock; 191, first interface; 192, second interface; 193, optical path interface; 194, stress release tube; 195, first tailstock; 196, second tailstock; 197, locking mechanism; 1971, locking sleeve; 1972, locking cap;

[0041] 200, light source device; 210, optical fiber connector; 220, optical fiber protective cover;

[0042] 1. Proximal end; 2. Distal end. DETAILED DESCRIPTION

[0043] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0044] It should be noted that when a component is referred to as being "connected" to another component, it may be directly connected to the other component or there may be a central component. When a component is referred to as being "disposed on" another component, it may be directly disposed on the other component or there may be a central component at the same time.

[0045] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those generally understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application. The term "and / or" used herein includes any and all combinations of one or more of the related listed items.

[0046] See also Figures 1 to 9The perfusion laser balloon catheter 100 provided in one embodiment of the present application has a relative proximal end 1 and a distal end 2, including a guide wire 110, an inner tube 120, an optical fiber 130, a balloon body 140 and a first outer tube 150; wherein the guide wire 110 is fixed with a blocking member 112 at the distal end, the inner tube 120 is fixedly sleeved on the outer periphery of the guide wire 110, and the distal end of the inner tube 120 is blocked by the blocking member 112, the inner tube 120 has a drug channel 121, and in order to effectively release the drug, the distal end of the inner tube 120 is provided with a first outlet 122 connected to the drug channel 121. The optical fiber 130 extends along the inner tube 120, and has a light-emitting section 131 at the distal end of the inner tube 120 for emitting light of a specific wavelength band. The balloon body 140 is located at the outer periphery of the inner tube 120, and the distal end of the balloon body 140 is sealed and connected to the outer wall of the inner tube 120; the first outer tube 150 is located at the outer periphery of the inner tube 120 and is connected to the proximal side of the balloon body 140, and the radial gap between the first outer tube 150 and the inner tube 120 serves as a fluid channel 151 for inflating the balloon body 140.

[0047] The perfusion laser balloon catheter 100 is used to treat vascular diseases, such as vascular stenosis. The inflated balloon body 140 can block the blood flow of the diseased segment in the blood vessel, and then deliver the drug through the drug channel 121 and release it through the first outlet 122 of the inner tube 120. In addition, the optical fiber 130 can emit light and act on the blood vessel through the inner tube 120 or stimulate the drug reaction to form a vascular microstent. Compared with the drug-loaded balloon catheter, the perfusion laser balloon catheter 100 provided in this embodiment can better release the drug and has better light uniformity, which is conducive to improving the treatment effect of vascular diseases.

[0048] See also Figure 1 , 9 In the illustrated embodiment, the perfusion laser balloon catheter 100 further includes a tailstock 190, the inner tube 120, the optical fiber 130 and the proximal end of the first outer tube 150 are all connected to the tailstock 190, and the tailstock 190 is provided with a first interface 191, a second interface 192 and an optical path interface 193, wherein the first interface 191 is communicated with the drug channel 121 for perfusing fluid drugs; the second interface 192 is communicated with the fluid channel 151 for perfusing fluid into the fluid channel 151 to inflate the balloon body 140; the optical path interface 193 corresponds to the optical fiber 130, and is used to facilitate the access of the optical fiber 130 to the light source device 200. The proximal end of the guide wire 110 extends and is connected to the tailstock 190.

[0049] Specifically, the inner tube 120 also has a guide wire 110 channel, such as a drug channel 121 as the guide wire 110 channel, the guide wire 110 is inserted into the drug channel 121 and the proximal end extends and is connected to the tailstock 190. The proximal end of the guide wire 110 can be movably set or fixedly set on the tailstock 190, and the fixed setting is, for example, to lock the proximal end of the guide wire 110 by a locking mechanism 197 that cooperates with the tailstock 190, and the locking mechanism 197 includes a locking sleeve 1971 and a locking cap 1972 that cooperate with each other, wherein the locking sleeve 1971 is fixed to the distal end of the tailstock 190, and the locking cap 1972 is movably matched with the guide wire 110.

[0050] A stress relief tube 194 is further provided at the proximal end of the tailstock 190 , and the proximal ends of the inner tube 120 and the first outer tube 150 are both connected to the stress relief tube 194 .

[0051] See also Fig. 9 In the illustrated embodiment, tailstock 190 comprises a first tailstock 195 and a second tailstock 196 of detachable matching, the first tailstock 195 is provided with a first interface 191 that is communicated with the drug passage, and the second tailstock 196 is provided with a second interface 192 that is communicated with the fluid passage 151 and an optical path interface 193 corresponding to the optical fiber. Specifically, the first tailstock 195 and the second tailstock 196 are connected by a Luer connector. In addition, the proximal ends of interior tube 120, first outer tube 150 and optical fiber 130 are all connected to the second tailstock 195, and locking mechanism 197 is arranged on the first tailstock 196.

[0052] There are multiple optical fibers 130, for example, four optical fibers, arranged along the circumference of the inner tube 120, and the arrangement is arranged at intervals, for example, arranged at equal intervals along the circumference of the inner tube 120, which can further improve the uniformity of light emission. There are many ways to fix the optical fiber 130, for example, see Figure 5 The optical fiber 130 extends along the interior of the inner tube 120 and is fixed to the inner wall of the inner tube 120, so as to avoid interfering with the movement of the guide wire 110. Figure 6 The wall of the inner tube 120 has a first installation channel 123, and the optical fiber 130 extends along the first installation channel 123. On the one hand, it can avoid interfering with the movement of the guide wire 110, and on the other hand, it can prevent the drug from adhering to the light-emitting section 131 of the optical fiber 130 and affecting the light-emitting effect.

[0053] See also Figure 7 , 8 In the illustrated embodiment, the optical fiber 130 extends along the outside of the inner tube 120 and is fixed to the outer wall of the inner tube 120. The perfusion laser balloon catheter 100 further includes a second outer tube 160, which is provided with a second outlet 162 communicating with the drug channel 121. The drug in the drug channel 121 needs to be released through the first outlet 122 and the second outlet 162 in sequence.

[0054] In one embodiment, the inner wall of the second outer tube 160 has a second installation channel 161, and the optical fiber 130 extends along the second channel, that is, the second outer tube 160 is a multi-lumen tube ( Figure 7 ), which plays a role in protecting the light-emitting segment 131 and preventing the drug from adhering to the light-emitting segment 131 and affecting the light-emitting effect.

[0055] Since there is a gap between the inner tube 120 and the second outer tube 160, the drug is easily retained in the gap, resulting in incomplete drug release and drug residue. To solve this problem, in one embodiment, a sealant 170 is poured into the radial gap between the second outer tube 160 and the inner tube 120, and the optical fiber 130 is buried in the sealant 170. The inner tube 120, the sealant 170 and the second outer tube 160 form a composite section, see Figure 8 .

[0056] To avoid affecting the luminous effect of the optical fiber 130, the sealant 170 uses a transparent glue with a high refractive index, such as a UV glue with a refractive index of 1.42 to 1.67, such as Loctite 3011 UV curing glue. The light scattered by the optical fiber 130 is refracted and then transmitted, making the illumination more uniform.

[0057] To ensure smooth release of the drug, the sealant 170 has an intermediate channel 171 connecting the first outlet 122 and the second outlet 162. The intermediate channel 171 can be a straight channel, and its two ends are connected to the first outlet 122 and the second outlet 162. Figure 8 , the first outlet 122 and the second outlet 162 are aligned, the intermediate channel 171 extends along the radial direction of the composite section and is connected to the first outlet 122 and the second outlet 162, that is, the drug is released along the radial direction of the composite section. For another example, the intermediate channel 171 can be set at an angle to the radial direction of the composite section, that is, the drug is released obliquely. In addition, according to the scene requirements, the composite section can be divided into multiple release zones, and each release zone is provided with a different intermediate channel 171, for example, divided into a proximal release zone, an intermediate release zone and a distal release zone. In the intermediate release zone, the drug is released along the radial direction of the composite section, and in the proximal release zone and the distal release zone, the drug is released obliquely relative to the axial direction of the composite section.

[0058] The composite section has an inner cavity and a side wall surrounding the inner cavity. The side wall has a first outlet 122, a middle channel 171 and a second outlet 162 to form a liquid outlet. The shape of the liquid outlet affects the effect of drug release. The shape of the liquid outlet can be a circular hole or a slit hole, see Fig.10 , 11 The diameter of the circular hole is 0.3-2 mm, for example, 1 mm; the slit hole can be a "I" hole, and the long diameter of the slit hole is 2-10 mm, and the short diameter is 0.01-0.1 mm, for example, the long diameter is 5 mm, the short diameter is 0.01 mm, and another example is the long diameter is 7 mm, and the short diameter is 0.05 mm.

[0059] To control the drug release rate, the porosity of the composite section is 40-70%, for example 50-70%, and for example 65%. Along the circumference of the composite section, at least two liquid discharge holes are provided between two adjacent optical fibers 130, for example, two liquid discharge holes are provided, and the spacing between the two liquid discharge holes is 0.5-1 mm.

[0060] See also Figure 1 , 3 In the illustrated embodiment, the guide wire 110 further includes a body section 111 and a guide section 113 respectively connected to both ends of the blocking member 112, wherein the proximal end of the body section 111 extends and is connected to the tailstock 190, and the guide section 113 extends out of the distal end of the inner tube 120. Considering the guiding effect of the guide wire 110, the length of the guide section 113 extending out of the distal end of the inner tube 120 is 3 to 5 cm.

[0061] The guide section 113 is an elastic member, such as a spring, which is formed by winding a metal wire, the material of the metal wire is stainless steel or platinum tungsten, and the diameter of the metal wire is 0.01-0.05 mm, such as 0.03 mm. The body section 111 of the guide wire 110 is made of metal, such as stainless steel, platinum tungsten or nickel-titanium alloy wire, and the material of the blocking member 112 is metal, such as stainless steel.

[0062] The material of the balloon body 140 is selected from silicone. The material of the inner tube 120 is selected from one of PTFE, HDPE, PA, and Pebax, preferably PTFE or HDPE, with a wall thickness of 0.025 to 0.1 mm. The material of the first outer tube 150 is selected from PA or Pebax, with a wall thickness of 0.025 to 0.1 mm. The material of the second outer tube 160 is selected from PA or Pebax, with a wall thickness of 0.025 to 0.1 mm.

[0063] A developing ring 180 is also disposed at the distal end of the inner tube 120 or the second outer tube 160. Usually, a plurality of developing rings 180 are disposed at intervals, for example, Figure 4 Two developing rings 180 are fixed at intervals at the far end of the second outer tube 160 , and the positions of the two developing rings 180 correspond to the two ends of the axial direction of the light-emitting segment 131 respectively.

[0064] See also Figure 1 , 9An embodiment of the present application provides a perfusion laser balloon catheter system, comprising the perfusion laser balloon catheter 100, a drug delivery device, a filling device, and a light source device 200, wherein the drug delivery device is used to supply a fluid containing a drug to the drug channel 121, the filling device is used to supply a fluid to the fluid channel 151 to inflate the balloon body 140, and the light source is used to be connected to the optical fiber 130 pipeline. Specifically, the drug delivery device supplies the fluid containing a drug to the drug channel 121 through the first interface 191, the filling device supplies the fluid to inflate the balloon body 140 to the fluid channel 151 through the second interface 192, and the light source is connected to the optical fiber 130 through the optical path interface 193.

[0065] The light source device 200 includes an optical fiber connector 210 and an optical fiber protective cover 220 , wherein the optical fiber protective cover 220 is made of TPU and can be used to protect the optical fiber 130 from bending.

[0066] See also Fig.12 An embodiment of the present application provides a method for processing a perfusion laser balloon catheter 100, comprising:

[0067] Step S100, connecting the first outer tube 150, the balloon body 140 and the second outer tube 160 end to end in sequence to obtain a first preform;

[0068] Step S200, arranging and fixing the optical fiber 130 along the outer circumference of the inner tube 120 to obtain a second preform;

[0069] Step S300, sleeve and fix the first preform on the outer circumference of the second preform, and fill the radial gap between the inner tube 120 and the second outer tube 160 with sealant 170, so that the inner tube 120, the sealant 170 and the second outer tube 160 form a composite section;

[0070] Step S400: The composite section has an inner cavity and a side wall surrounding the inner cavity, and a liquid outlet hole communicating with the inner cavity is provided on the side wall.

[0071] Specifically, in step S100, the balloon body 140 has a proximal end and a distal end opposite to each other, the proximal end of the balloon body 140 is connected to the end of the first outer tube 150, and the distal end of the balloon body 140 is connected to the end of the second outer tube 160, so that the first outer tube 150, the balloon body 140 and the second outer tube 160 are connected end to end in sequence. The connection can be made by gluing and / or welding, wherein gluing and welding are, for example, ultrasonic welding and hot pressing welding.

[0072] In step S200, the inner tube 120 has a relative proximal end and a distal end, and the portion of the optical fiber 130 located at the distal end of the inner tube 120 is exposed as a light-emitting segment 131. Specifically, the optical fiber 130 includes an inner core 132 and a sheathing layer, and the sheathing layer wraps the inner core 132 to protect the optical fiber 130 and reduce the energy loss of the optical fiber 130. The portion of the optical fiber 130 located at the distal end of the inner tube 120 is stripped of the sheathing to serve as the light-emitting segment 131. The stripping method may be physical stripping (e.g., sandblasting, grinding, scraping, etc.) or chemical stripping. The surface of the light-emitting segment 131 is ground to make the surface more uniform and improve the uniformity of light emission.

[0073] Multiple optical fibers 130, for example, four optical fibers 130, are fixed at intervals along the outer periphery of the inner tube 120. The optical fibers 130 can be fixed by gluing or splicing. In step S300, when the first preform is sleeved and fixed on the outer periphery of the second preform, the second outer tube 160 is sleeved on the outer periphery of the light-emitting segment 131.

[0074] The connection between the second outer tube 160 and the balloon body 140 is sealed to the outer wall of the inner tube 120, and the free section of the second outer tube 160 is sealed to the outer wall of the inner tube 120, so that both ends of the second outer tube 160 are closed. The sealing connection can be made by gluing or welding.

[0075] For example, in one embodiment, the sealing connection is achieved by using a glue injection mechanism to inject glue into the radial gap between the inner tube 120 and the second outer tube 160. Specifically, the glue injection mechanism has a tubular glue injection head. Before injecting glue, the glue injection head extends into the radial gap until the connection between the second outer tube 160 and the balloon body 140. When injecting glue, the glue injection head withdraws toward the distal end of the inner tube 120 while injecting glue until the radial gap is filled with the sealant 170.

[0076] Since the optical fiber 130 is embedded in the sealant 170, in order to ensure the light transmission effect, the sealant 170 uses a transparent glue with a high refractive index, such as a UV glue with a refractive index of 1.42 to 1.67, such as Loctite 3011 UV curing glue. The light scattered by the optical fiber 130 is refracted and then transmitted, making the illumination more uniform.

[0077] In step S400, laser drilling is used to drill holes from the outside to the inside of the side wall of the composite section, and the second outer tube 160, the sealant 170 and the inner tube 120 are penetrated in sequence to form a liquid outlet. The power of the laser drilling is 300-500mW, for example, 300-400mW, and for example, 320mW. Medical catheter laser drilling equipment can be used for drilling holes, such as the medical catheter drilling machine of Chuangxuan Laser. By setting different drilling shapes and sizes, circular holes and slit holes can be punched on the catheter, and the slit holes are, for example, "I" holes; specifically, the laser head is usually point-shaped. According to the shape of the expected liquid outlet, different walking paths of the laser head can be set to obtain liquid outlets of different shapes. Furthermore, the composite section is provided with two rows of liquid outlets in the area between two adjacent optical fibers 130.

[0078] The perfusion laser balloon catheter 100 is also provided with a developing ring 180. During processing, the developing ring 180 can be fixed to the outer periphery of the second preform in step S200, that is, the outer periphery of the inner tube 120; or the developing ring 180 can be fixed to the outer periphery of the composite section in step S400, that is, the outer periphery of the second outer tube 160.

[0079] The perfusion laser balloon catheter 100 also includes a guide wire 110 fixedly inserted into the inner tube 120, and the guide wire 110 includes a guide section 113, a blocking member 112, and a body section 111 connected in sequence, wherein the guide section 113 extends out of the distal end of the inner tube 120, the blocking member 112 blocks the distal end of the inner tube 120, and the body section 111 extends out of the proximal end of the inner tube 120. At least a portion of the distal end of the guide wire 110 is fixed to the distal end of the inner tube 120, for example, the blocking member 112 is fixed to the distal end of the inner tube 120, and the fixing method can be adhesive or welding.

[0080] Regarding the timing of fixing the guide wire 110, in one embodiment, the guide wire 110 is inserted into the second preform of step S200, i.e., the outer periphery of the inner tube 120, the surface of the sealing member 112 is pre-coated with a colloid, the sealing member 112 is pushed to a predetermined position of the inner tube 120, and then the sealing member 112 is bonded to the side wall of the inner tube 120 by heat pressing or ultrasound.

[0081] The perfusion laser balloon catheter 100 further includes a tailstock 190, and the processing method further includes step S500. After step S400, a fourth preform is obtained, and the proximal end of the fourth preform is connected to the tailstock 190, and the proximal end of the guide wire 110 extends out of the tailstock 190. The connection method can be gluing and / or welding.

[0082] The perfusion laser balloon catheter 100 provided in the present application has good light emission uniformity, simple drug release, and is not prone to drug residue, and can effectively improve the treatment effect on vascular diseases.

[0083] The technical features of the above-mentioned embodiments can be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification. When the technical features in different embodiments are embodied in the same figure, it can be regarded that the figure also discloses the combination examples of the various embodiments involved.

[0084] The above-described embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.

Claims

1. An irrigated laser balloon catheter having opposed distal and proximal ends, It is characterized in that The perfusion laser balloon catheter comprises: A guide wire having an occluding member fixed at a distal portion thereof; An inner tube, fixedly sleeved on the outer circumference of the guide wire, and the distal end of the inner tube is blocked by the blocking member, the inner tube has a drug channel, and the distal end of the inner tube is provided with a first outlet connected to the drug channel; An optical fiber extends along the inner tube, wherein the optical fiber has a light-emitting segment at a distal end of the inner tube; A balloon body is disposed on the outer periphery of the inner tube, and a distal end of the balloon body is sealed and connected to the outer wall of the inner tube; The first outer tube is located at the outer periphery of the inner tube and is communicated with the proximal end of the balloon body. The radial gap between the first outer tube and the inner tube serves as a fluid channel for inflating the balloon body.

2. The perfusion laser balloon catheter according to claim 1, It is characterized in that The perfusion laser balloon catheter also includes a tail seat, and the inner tube, the optical fiber and the proximal ends of the first outer tube are all connected to the tail seat. The tail seat is provided with a first interface connected to the drug channel, a second interface connected to the fluid channel and an optical path interface corresponding to the optical fiber, and the proximal end of the guide wire extends and is connected to the tail seat.

3. The perfusion laser balloon catheter according to claim 1, It is characterized in that The optical fiber extends along the interior of the inner tube and is fixed to the inner wall of the inner tube.

4. The perfusion laser balloon catheter according to claim 1, It is characterized in that The tube wall of the inner tube is provided with a first installation channel, and the optical fiber extends along the first installation channel.

5. The perfusion laser balloon catheter according to claim 1, It is characterized in that The guide wire comprises a body section and a guide section respectively connected to two ends of the blocking member, and the guide section extends out of the distal end of the inner tube; The length of the guide section extending out of the distal end of the inner tube is 3 to 5 cm.

6. The perfusion laser balloon catheter according to claim 1, It is characterized in that The optical fiber extends along the outside of the inner tube and is fixed to the outer wall of the inner tube. The perfusion laser balloon catheter also includes a second outer tube, and the second outer tube is provided with a second outlet communicated with the drug channel.

7. The perfusion laser balloon catheter according to claim 6, It is characterized in that The inner wall of the second outer tube is provided with a second installation channel, and the optical fiber extends along the second installation channel.

8. The perfusion laser balloon catheter according to claim 6, It is characterized in that A sealant is poured into the radial gap between the second outer tube and the inner tube, and the optical fiber is buried in the sealant.

9. The perfusion laser balloon catheter according to claim 6, It is characterized in that The sealant has a middle channel communicating with the first outlet and the second outlet.

10. Perfusion laser balloon catheter system, It is characterized in that include: A perfusion laser balloon catheter, comprising the perfusion laser balloon catheter as claimed in any one of claims 1 to 9; a drug delivery device for supplying a fluid containing a drug to the drug passage; a filling device, for supplying fluid to the fluid channel to inflate the balloon body; A light source device is used to connect with the optical fiber light path.

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