Special cryoprecipitation constant-temperature storage box for blood transfusion department

Abstract

The invention relates to the technical field of medical equipment, in particular to a cryoprecipitation constant-temperature preservation box special for the blood transfusion department, which comprises a box body and a box cover, a placing plate is arranged in the box body, a connecting cylinder is fixedly connected to the bottom end of the placing plate, a temperature adjusting chamber is arranged on the outer side of the connecting cylinder, and a plurality of thermoelectric refrigeration sheets are arranged in the temperature adjusting chamber; a temperature sensor is fixedly connected to the side wall of the box body and is in signal connection with a control system; a storing and taking wall and a drainage wall are arranged on the inner wall of the box body, symmetrical circulation channels are formed in the storing and taking wall, a negative pressure chamber is formed in the containing plate, an airflow driving assembly is arranged in the negative pressure chamber, and a plurality of air return holes are formed in the surface of the containing plate. And a circulating airflow flowing mechanism is arranged, so that air in the box body can uniformly cover each blood cryoprecipitation bag, the influence of non-uniform temperature distribution on the preservation quality is reduced, and the temperature control stability of the preservation box body is improved.

Description

Technical Field

[0001] The invention relates to the technical field of medical equipment, and in particular to a cold precipitation constant temperature storage box dedicated to a blood transfusion department. Background Art

[0002] There are specific requirements for the storage of thawed blood cryoprecipitate bags. Blood cryoprecipitate bags are components that precipitate during the blood thawing process, mainly containing fibrinogen, von Willebrand factor (vWF), plasminogen, etc., which play an important role in the treatment of coagulation disorders, hemophilia and other diseases. Its storage temperature must be strictly controlled between 20-24°C to ensure that its biological activity is not damaged. At the same time, the thawed blood cryoprecipitate bag should be kept at this temperature for no more than 6 hours to avoid component degradation or loss of activity due to long-term storage.

[0003] In order to achieve accurate preservation of the blood cryoprecipitate bag after thawing, the Chinese patent announcement number CN109592185A discloses a platelet constant temperature oscillation storage box for blood transfusion department, including a box body, a partition is arranged in the box body, the partition divides the box body into an upper box body and a lower box body, the lower surface of the upper box body and the lower box body are both provided with a heating plate, and the upper box body and the lower box body are both provided with more than one temperature sensor, and the two side walls of the upper box body are both provided with a retaining frame, the retaining frame is a T-shaped frame, the vertical section of the retaining frame passes through the side wall of the upper box body and is connected with a rotating mechanism, and a box body is arranged between the horizontal sections of the two retaining frames; a water injection port is opened at the upper end of the upper box body, a through hole is opened on the partition, and a water circulation mechanism is arranged in the box body, and the water circulation mechanism allows the liquid to flow between the upper box body and the lower box body. The beneficial effects of the invention are: through the contact between the liquid and the platelet blood bag, the heat transfer between the liquid molecules is accelerated, and the liquid temperature is processed in advance to reach the target temperature, that is, the storage temperature of the platelet blood bag is uniform everywhere.

[0004] However, the above device needs to monitor that the temperature in the box exceeds the preset temperature threshold before the liquid can be pumped and released. The pumping of a liquid flow results in heat loss, which causes different levels of blood bags to be regulated by the liquid temperature and have different heat exchange efficiencies. This causes the temperature of each placement plate to fluctuate greatly, resulting in different quality and activity of platelets at different levels. When this design is applied to the storage of thawed blood cryoprecipitate bags, it will also cause uneven sample storage temperature. In addition, the storage of thawed blood cryoprecipitate bags is different from the storage of platelets, and there is no need to oscillate the sample. For this reason, it is necessary to design a special cryoprecipitate constant temperature storage box for the blood transfusion department to improve the stability of temperature control during storage, ensure the uniformity of sample storage temperature distribution, and improve the preservation effect of thawed blood cryoprecipitate bags. Summary of the invention

[0005] In order to solve the above problems, the present invention provides a cold precipitation constant temperature storage box specially used for blood transfusion department, which realizes the control of the temperature inside the box through thermoelectric cooling sheet combined with intelligent temperature acquisition, and sets a circulating airflow flow mechanism so that the air in the box can evenly cover each blood cold precipitation bag, thereby reducing the influence of uneven temperature distribution on the storage quality and improving the stability of the temperature control of the storage box.

[0006] In order to achieve the above-mentioned purpose, the technical scheme of the present invention is as follows: a cold precipitation constant temperature storage box for blood transfusion department, comprising a box body and a box cover, the box cover is detachably connected to the box body, a sealing ring is sleeved on the bottom of the box cover, a placement plate is arranged in the box body, a hollow connecting cylinder is fixedly connected to the bottom end of the placement plate, the bottom end of the connecting cylinder is fixedly connected to the bottom wall of the box body, a temperature regulating chamber is arranged outside the connecting cylinder, a plurality of thermoelectric cooling sheets are arranged in the temperature regulating chamber, a temperature sensor is fixedly connected to the side wall of the box body, the temperature sensor signal is connected to the control system, and the plurality of thermoelectric cooling sheets are all connected to the control system signal;

[0007] The control system is used to receive real-time temperature data collected by the temperature sensor and control several thermoelectric cooling chips to maintain the temperature in the box between 20-24°C.

[0008] The inner wall of the box is provided with a storage wall and a drainage wall from top to bottom, and the storage wall and the drainage wall are integrally formed with the box. The chamber corresponding to the storage wall is the storage chamber, and the chamber corresponding to the drainage wall is the storage chamber. Symmetrical circulation channels are opened on the storage wall, and the two ends of the circulation channels are respectively connected to the storage chamber and the storage chamber. A number of through holes are evenly opened on the side wall of the connecting cylinder in the circumference, a negative pressure chamber is opened in the placement plate, an airflow driving component is arranged in the negative pressure chamber, and a number of return air holes are opened on the surface of the placement plate, and the two ends of the return air holes are respectively connected to the negative pressure chamber and the storage chamber. When the airflow driving component is started, the airflow in the box flows along the through hole, the drainage wall, the circulation channel to the return air hole in sequence to form a flow cycle.

[0009] The technical principle of the above scheme is as follows: through the signal connection of the temperature sensor and the control system, the real-time temperature data in the box is detected, and through the signal connection of a number of thermoelectric cooling sheets and the control system, the temperature in the box is controlled within the range of 20-24°C; the three-dimensional airflow path is formed by the storage and access wall, the circulation channel, the guide surface of the guide wall and the through holes on the placement plate. When the airflow drive component is started, a closed-loop airflow is formed with air intake through the through holes, air diversion through the guide wall, backflow through the circulation channel and negative pressure suction through the return air hole.

[0010] The above scheme has the following beneficial effects:

[0011] 1. Cold precipitate is rich in heat-sensitive biomacromolecules such as coagulation factor VIII, and its three-dimensional conformation will undergo irreversible changes outside the range of 20-24°C, resulting in loss of coagulation function. Traditional temperature control methods have temperature fluctuations of ±2°C, which can easily cause the problem of decreased activity of cold precipitate. This solution uses thermoelectric refrigeration chips combined with intelligent temperature acquisition to control the temperature inside the box. The control system uses temperature sensors to feedback temperature data in real time and dynamically adjusts the cooling or heating power of the thermoelectric refrigeration chips. When the door is opened to cause heat or cold intrusion, the system can respond quickly to ensure that the blood cold precipitate bag is always in the best activity preservation window, thereby improving the clinical infusion efficacy.

[0012] 2. Due to the static storage environment, temperature gradients are prone to occur in the box, and the internal temperature may deviate from the set value, resulting in poor preservation of the cold precipitate. This solution adopts a circulating airflow flow mechanism so that the air in the box can evenly cover each blood cold precipitate bag, reducing the impact of uneven temperature distribution on the preservation quality. The airflow drive component forms a negative pressure environment in the negative pressure chamber, drives the airflow to circulate, ensures heat exchange efficiency, and avoids direct blowing on the cold precipitate bag to cause mechanical damage, thereby improving the efficiency of air heat exchange in the box and controlling the humidity in the box to provide a dry and uniform preservation microenvironment for the cold precipitate.

[0013] Furthermore, the opening direction of the circulation channel connected to one end of the access chamber is directed to the storage chamber, and the airflow in the box body returns to the storage chamber through the circulation channel during the flow circulation.

[0014] Beneficial effect: The directional design of the opening makes the circulation channel have the effect of a directional heat exchange channel. When the airflow passes through the thermoelectric cooling plate in the channel, a laminar flow state is formed. After being guided into the circulation channel by the drainage wall, it returns to the storage room, thereby improving the heat exchange efficiency of the circulating airflow.

[0015] Furthermore, the inner wall of the circulation channel is a Venturi tube structure. When medical staff open the cover to access the blood cryoprecipitate bag, the airflow passes through the circulation channel to form a vortex ring airflow curtain in the access chamber.

[0016] Beneficial effects: The blood transfusion department's operating specifications require a high frequency of cold sediment storage and retrieval. Traditional equipment has the problem of temperature changes every time the door is opened. At this time, it takes time for the temperature in the box to return to normal. This solution sets up an independent storage and access room and cooperates with the Venturi effect of the circulation channel to form a vortex ring airflow curtain to block the intrusion of hot air or cold air, reduce the heat exchange efficiency between the air in the box and the outside air, and ensure the stability of the storage room temperature.

[0017] Furthermore, the airflow driving component includes an outer shell, the outer wall of the outer shell is fixedly connected to the inner wall of the negative pressure chamber, the outer shell is rotatably connected with a rotating blade, the bottom wall of the box is fixedly connected to a servo motor corresponding to the position of the rotating blade, and the output shaft of the servo motor passes through the bottom wall of the outer shell and is coaxially fixedly connected to the rotating blade.

[0018] Beneficial effects: The design of the rotating blades generates a directional negative pressure gradient field driven by a servo motor. This negative pressure field causes the airflow to form a spiral downward flow along the circulation channel, establishes a stable laminar flow circulation in the storage room, and improves the organization efficiency of the airflow in the box.

[0019] Furthermore, the servo motor is connected to the control system signal, and the control system adjusts the rotation power of the servo motor according to the temperature of the box body, so that the driving power of the servo motor is inversely proportional to the difference.

[0020] Beneficial effects: The servo motor and control system form a closed-loop speed regulation system, which realizes dynamic speed regulation through signal connection. When the temperature of the storage room deviates from the set value, the control system adjusts the motor speed in real time according to the deviation value. This dynamic matching keeps the air flow speed balanced with the heat load at all times, which is more energy-efficient than traditional fixed-speed fans.

[0021] Furthermore, several thermoelectric cooling sheets are arranged vertically, one end of the thermoelectric cooling sheets is fixedly connected to the connecting tube, and the other end of the thermoelectric cooling sheets is fixedly connected to the inner wall of the box body. The gap between adjacent thermoelectric cooling sheets is a temperature adjustment unit, and the position and number of the temperature adjustment units correspond to the position and number of the through holes.

[0022] Beneficial effects: The vertically arranged thermoelectric cooling chips form a cold surface array perpendicular to the airflow. Each thermoelectric cooling chip is independently temperature-controlled, and the spatial distribution of cooling capacity is controlled through the control system. This layout reduces the horizontal and vertical temperature differences in the storage room, and can improve temperature uniformity compared to traditional flat cooling solutions. In addition, the temperature adjustment unit between adjacent cooling chips forms a fault isolation zone. When a single cooling chip fails, the control system automatically increases the power of adjacent cooling chips, reduces the failure rate, improves equipment reliability, and meets the safety standards of medical equipment.

[0023] Furthermore, a plurality of protrusions with a honeycomb structure are provided on the top surface of the placement plate, and air passages are provided between adjacent protrusions.

[0024] Beneficial effects: The airway realizes the function of a venturi tube, accelerates the airflow speed in the airway, produces a venturi effect, strengthens the convection heat exchange of cold and hot air, and improves the heat exchange coefficient of the placement plate surface. In addition, the honeycomb structure forms a uniform temperature field at the bottom of the blood cryoprecipitation bag. The honeycomb structure can reduce the surface temperature difference, improve the uniformity of temperature distribution, and ensure that each bag of blood cryoprecipitation bag is in the same thermal environment.

[0025] Furthermore, the protrusions are all made of a paraffin mixture material. When the temperature inside the box changes, the protrusions undergo phase change according to the temperature change, releasing or storing latent heat. At the same time, the width of the airway changes with the phase change expansion of the protrusions, and the change in the width of the airway is proportional to the temperature.

[0026] Beneficial effects: Each protrusion unit can store latent heat of phase change. When the temperature of the box fluctuates, the protrusion absorbs or releases heat through solid-liquid phase change to form a temperature buffer layer, which reduces the temperature fluctuation range of the surface of the blood cryoprecipitation bag and meets the storage temperature requirements of the blood cryoprecipitation bag. In addition, the solid-liquid change of the protrusion causes the volume of the protrusion to change, achieving the effect that the width of the airway is proportional to the temperature. When the airway width is reduced, a closed insulation layer is formed; when the airway width is expanded, heat dissipation is enhanced. This adaptive adjustment can dynamically adjust the system thermal resistance of the device to achieve intelligent thermal management.

[0027] Furthermore, a display screen is embedded and fixed on the top of the box, and the display screen is connected to the control system signal.

[0028] Beneficial effects: The display screen can display the temperature data and humidity output of the storage room in real time. Through the control system, the complex sensor data is converted into intuitive data presentation, so that the operator can understand the temperature conditions in the storage room and facilitate emergency response.

[0029] Furthermore, the control system includes a temperature acquisition module, a display module, an analysis module, a regulation module and a drive module;

[0030] The temperature acquisition module is used to receive the real-time temperature signal in the box collected by the temperature sensor, convert the real-time temperature signal into real-time temperature data, and transmit the real-time temperature data to the display module, the analysis module and the adjustment module;

[0031] A display module is used to receive the real-time temperature data transmitted by the temperature acquisition module, convert the temperature data into a display signal, and transmit the display signal to a display screen, which displays the real-time temperature in the box;

[0032] The analysis module is used to receive the real-time temperature data, and when the real-time temperature data is greater than 24°C or the real-time temperature data is less than 20°C, the difference between the real-time temperature data and 24°C or the absolute value of the difference between the real-time temperature data and 20°C is calculated, and the rotation drive signal converted into different rotation powers of the servo motor is calculated according to the difference and the absolute value of the difference, and then the rotation drive signal is transmitted to the drive module, and when the real-time temperature is between 20-24°C, the rotation stop drive signal is transmitted to the drive module;

[0033] The regulating module is used to receive real-time temperature data, and transmit a cooling drive signal to a plurality of thermoelectric cooling sheets when the real-time temperature data is greater than 24°C, and transmit a heating drive signal to a plurality of thermoelectric cooling sheets when the real-time temperature data is less than 20°C, and transmit a regulating stop drive signal to a plurality of thermoelectric cooling sheets when the real-time temperature data is between 20-24°C;

[0034] The driving module is used to receive the rotation driving signal or the rotation stop driving signal transmitted by the analysis module, and transmit the rotation driving signal or the rotation stop driving signal to the servo motor.

[0035] Beneficial effect: The temperature data in the box is collected by the temperature sensor in conjunction with the control system. When the temperature in the storage room fluctuates, the system can respond quickly and improve the stability of temperature control by adjusting the speed of the servo motor and the power of the thermoelectric cooling chip.

[0036] Additional aspects and advantages of the present invention will be given in part in the following description and in part will be obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Figure 1 This is a schematic diagram of the overall structure of an embodiment of a cryoprecipitation constant temperature storage box dedicated to a blood transfusion department of the present invention;

[0038] Figure 2 It is an axonometric cross-sectional schematic diagram of an embodiment of a cryoprecipitate constant temperature storage box dedicated to a blood transfusion department of the present invention;

[0039] Figure 3 This is a schematic diagram of the airflow circulation in the box in the embodiment of the cryoprecipitation constant temperature storage box for blood transfusion department of the present invention;

[0040] Figure 4 It is a schematic diagram showing the effect of opening the cover of the cryoprecipitation constant temperature storage box for blood transfusion department on the air flow velocity in the embodiment of the present invention;

[0041] Figure 5 The invention is a special cryoprecipitation constant temperature storage box for blood transfusion department. Figure 2 A schematic diagram of the effect of the airway on the airflow velocity;

[0042] Figure 6 The invention is a special cryoprecipitation constant temperature storage box for blood transfusion department. Figure 2 The enlarged schematic diagram of the circulation channel at B in the middle;

[0043] Figure 7 It is a schematic diagram of the operation of the control system in the embodiment of the cryoprecipitate constant temperature storage box for blood transfusion department of the present invention.

[0044] The figure marks in the drawings of the specification include: 1. box body; 2. box cover; 3. placement plate; 4. connecting tube; 5. thermoelectric cooling plate; 6. temperature sensor; 7. storage and access wall; 701. storage and access chamber; 8. drainage wall; 801. storage chamber; 9. circulation channel; 10. through hole; 11. negative pressure chamber; 12. return air hole; 13. outer shell; 14. rotating blade; 15. servo motor; 16. protrusion; 17. air duct; 18. display screen. DETAILED DESCRIPTION

[0045] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0046] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0047] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0048] The following is further described in detail through specific implementation methods:

[0049] Embodiment 1:

[0050] As attached Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 and Figure 6 As shown: A cold precipitation constant temperature storage box specially used for blood transfusion department comprises a box body 1 and a box cover 2. A take-in and put-out opening corresponding to the shape and size of the box cover 2 is provided on the top of the box body 1. The box cover 2 is detachably connected to the box body 1 through the take-in and put-out opening. A sealing ring is sleeved on the bottom of the box cover 2. The design of the sealing ring can effectively isolate the air outside the box body 1 from entering the box body 1, and also prevent the air inside the box body 1 from overflowing, thereby avoiding any adverse effect on the temperature control inside the box body 1 and ensuring that the blood cold precipitation bag can be properly stored in a constant temperature environment.

[0051] Regarding the temperature control in the box 1, a placement plate 3 is provided in the box 1, and the placement plate 3 is used to carry a blood cold precipitation bag, that is, the medical staff places the blood cold precipitation bag on the surface of the placement plate 3, and a hollow connecting tube 4 is welded at the bottom end of the placement plate 3, and the bottom end of the connecting tube 4 is welded to the bottom wall of the box 1, and a temperature adjustment chamber is provided on the outside of the connecting tube 4, and a plurality of thermoelectric cooling sheets 5 are arranged in the temperature adjustment chamber. A temperature sensor 6 is fixedly connected to the side wall of the box 1 by screws, and the temperature sensor 6 is used to monitor the temperature inside the box 1 in real time. The temperature sensor 6 signal is connected to a control system, and the control system is used to receive the temperature signal detected by the temperature sensor 6, and analyze whether the temperature in the box 1 is within the temperature range of 20-24°C. The plurality of thermoelectric cooling sheets 5 are all connected to the control system signal, and the control system analyzes the temperature and transmits the corresponding driving signal to the plurality of thermoelectric cooling sheets 5 according to the temperature conditions, so as to drive the plurality of thermoelectric cooling sheets 5 to adjust the temperature.

[0052] The special thing is that the inner wall of the box body 1 is provided with a storage wall 7 and a drainage wall 8 from top to bottom, and the storage wall 7 and the drainage wall 8 are integrally formed with the box body 1. The chamber corresponding to the storage wall 7 is the storage chamber 701, and the chamber corresponding to the drainage wall 8 is the storage chamber 801. Figure 2 As shown, the cross-sectional area of ​​the inner side of the access wall 7 is equal to the area of ​​the placement plate 3, and a symmetrical circulation channel 9 is opened on the access wall 7. Both ends of the circulation channel 9 are connected to the access chamber 701 and the storage chamber 801 respectively. The opening direction of the circulation channel 9 connected to the access chamber 701 is directed to the storage chamber 801. The airflow in the temperature regulating chamber that is regulated by the thermoelectric cooling sheet 5 can enter the circulation channel 9 through the drainage effect of the drainage wall 8. Due to the design of the direction of the opening of the circulation channel 9, these gases form an orderly reflux flow in the channel, as shown in FIG. Figure 3 As shown, heat or cold can be effectively exchanged and recycled between the access chamber 701 and the storage chamber 801. For example, before the hot air flow passes through the circulation channel 9, it transfers part of the heat to the blood cryoprecipitation bag in the storage chamber 801, while its own temperature gradually decreases. Subsequently, this part of the cooled air flow flows back to the storage chamber 801 through the circulation channel 9 and the access chamber 701, and mixes with the subsequent hot air flow in the storage chamber 801, further promoting the uniform distribution of temperature.

[0053] Secondly, the inner wall of the circulation channel 9 is a Venturi tube structure. When the airflow passes through the circulation channel 9, the circulation channel 9 can accelerate the airflow. When the medical staff opens the box cover 2 to deposit or take out the blood cold sedimentation bag, when the box cover 2 and the sealing ring are released, the enclosed space inside the box body 1 generates a transient pressure gradient due to the pressure balance requirement. At this time, the storage space in the box body 1 and the external environment form a pressure difference driven flow field. Under the combined influence of buoyancy and Bernoulli effect, the cold air or hot air forms a directional rising airflow along the inner wall of the box body 1. The movement trajectory of the rising airflow is affected by the drainage effect of the drainage wall 8, so that the airflow flows along the wall and merges into the circulation channel 9. The circulation channel 9 adopts a Venturi tube structure, and its tapered section accelerates the airflow, forming a low pressure area at the throat, driving the airflow to flow downstream (near the storage chamber 801). In this process, the turbulent boundary layer of the accelerated airflow is periodically separated from the inner wall of the access wall 7 to form a shear layer with an axial velocity gradient. When the main flow gas exchanges momentum with the secondary flow gas at the outlet of the circulation channel 9, the shear layer becomes unstable and rolls up to form a coherent vortex ring structure. These vortex rings break away from the trailing edge of the access wall 7 at a specific frequency, that is, move toward the center of the box 1, and build a dynamically balanced vortex ring airflow curtain in the upper space of the box 1, such as Figure 4 As shown, the generation of the vortex ring airflow curtain, on the one hand, can effectively inhibit molecular heat conduction due to the centrifugal force field perpendicular to the mainstream direction generated by the rotational motion, that is, reduce the heat exchange between the airflow in the box 1 and the external airflow at the moment of opening the cover; on the other hand, the secondary flow induced by the vortex ring airflow curtain forms a stable temperature stratification at the top of the box 1, thereby improving the stability of temperature control in the box 1.

[0054] In order to improve the stability of temperature control in the box body 1, a plurality of through holes 10 are designed to be evenly opened on the side wall of the connecting tube 4 in the circumferential direction. Correspondingly, a negative pressure chamber 11 is opened in the placement plate 3, and a plurality of return air holes 12 are opened on the surface of the placement plate 3. Both ends of the return air holes 12 are respectively connected to the negative pressure chamber 11 and the storage chamber 801. An airflow driving component for driving the airflow to flow from top to bottom is provided in the negative pressure chamber 11. The airflow driving component includes an outer shell 13. The outer wall of the outer shell 13 is fixedly connected to the inner wall of the negative pressure chamber 11 by a snap-fit ​​structure. Rotating blades 14 are rotatably connected to the outer shell 13 through bearings. The bottom wall of the box body 1 is fixedly connected to a servo motor 15 corresponding to the position of the rotating blades 14 by bolts. The output shaft of the servo motor 15 passes through the bottom wall of the outer shell 13 and is coaxially fixedly connected to the rotating blades 14 through a coupling. When the servo motor 15 is started, the rotating blades 14 start to rotate, generating an airflow driving flow force. The airflow in the storage chamber 801 is sucked into the negative pressure chamber 11 through the air return hole 12, and then driven by the rotating blades 14, the airflow flows from top to bottom and enters the temperature regulating chamber through the through hole 10. Subsequently, the airflow continues to circulate in the access chamber 701 and the storage chamber 801 to form a closed airflow circulation loop. By controlling the flow path of the airflow, the airflow is evenly distributed and circulated in the box body 1, which helps to evenly distribute the heat in the box body 1, thereby improving the stability of temperature control.

[0055] In addition, the servo motor 15 is connected to the control system signal, and the control system can dynamically adjust the rotation power of the servo motor 15 according to the difference between the real-time temperature and the set temperature threshold (20 / 24°C). For example, when the temperature is closer to 24°C, in order to adjust the temperature more finely and avoid overheating or overcooling, the control system will increase the rotation power of the servo motor 15. At this time, the speed of the rotating blade 14 will increase accordingly, accelerating the circulation of the airflow, thereby taking away or replenishing heat more quickly, so that the temperature inside the box 1 is kept within a more stable range. By adjusting the rotation power of the servo motor 15 in real time, the control system can more accurately control the temperature inside the box 1, reduce temperature fluctuations, and improve the accuracy of temperature control. Secondly, accelerating the circulation of the airflow helps to respond more quickly to changes in the external temperature or the generation and dissipation of heat inside the box 1, and enhances the dynamic response capability of the system. Furthermore, this intelligent adjustment method can be automatically adjusted according to actual needs without manual intervention, improving the automation and convenience of the system, and by optimizing the airflow circulation, effectively reducing the temperature gradient, so that the temperature inside the box 1 is more uniform.

[0056] Embodiment 2:

[0057] As attached Figure 2As shown, the difference from Example 1 is that, in order to improve the stability of temperature control, several thermoelectric cooling sheets 5 are designed to be arranged vertically, one end of the thermoelectric cooling sheet 5 is welded to the connecting tube 4, and the other end of the thermoelectric cooling sheet 5 is welded to the inner wall of the box body 1. The gap between adjacent thermoelectric cooling sheets 5 is a temperature regulating unit. The position and number of the temperature regulating units correspond one-to-one to the position and number of the through holes 10. When the airflow flows out through the through holes 10, it will directly pass through the corresponding temperature regulating units. When the airflow flows through these units, it will fully exchange heat with the surface of the thermoelectric cooling sheet 5, thereby absorbing or releasing heat, so that the temperature of the airflow is adjusted. On the one hand, due to the one-to-one correspondence between the temperature regulating units and the positions of the through holes 10, the airflow can fully contact the thermoelectric cooling sheet 5 during the outflow process, ensuring the sufficiency and uniformity of the heat exchange. On the other hand, the vertical arrangement of the thermoelectric cooling sheet 5 maximizes its surface area, further improving the efficiency of heat exchange, which not only improves the stability of temperature control, but also makes the temperature distribution inside the box 1 more uniform. No matter how the external environment changes, or how much heat is generated inside the box 1, the precise control of the thermoelectric cooling sheet 5 and the effective heat exchange of the airflow can ensure that the temperature inside the box 1 remains within the set range, providing a more stable and reliable temperature environment for the storage of the blood cold sedimentation bag.

[0058] Embodiment 3:

[0059] As attached Figure 5 As shown, the difference from Example 2 is that when a blood cryoprecipitation bag is placed on the surface of the placement plate 3, the airflow in the box body 1 will pass through the surface of the blood cryoprecipitation bag, exchange heat with the blood cryoprecipitation bag, and then gather on the top surface of the placement plate 3. The top surface of the placement plate 3 is designed to be provided with a plurality of protrusions 16 with a honeycomb structure, and an air passage 17 is provided between adjacent protrusions 16. The design of the air passage 17 is similar to a tapered Venturi structure. When the circulating airflow of the box body 1 flows through the plurality of protrusions 16, the airflow is accelerated in the air passage 17. After the airflow collides with the surface of the protrusion 16, the turbulent boundary layer is separated, and a coherent turbulence is formed through a periodically shed vortex street structure, such as Figure 5 The air flow streamlines shown in the figure enhance the convective heat transfer efficiency.

[0060] Embodiment 4:

[0061] As attached Figure 1 and Figure 2 As shown, the difference from Example 3 is that a display screen 18 is embedded on the top of the box body 1, and the display screen 18 is connected to the control system signal. The design of the display screen 18 can display the temperature in the box body 1, the set temperature and other information in real time. Through the control system, the complex sensor data is converted into an intuitive data presentation, so that the operator can understand the temperature conditions in the storage room 801, which is convenient for the operator to carry out emergency processing.

[0062] Embodiment 5:

[0063] As attached Figure 7 As shown, the difference from Example 4 is that the control system includes a temperature acquisition module, a display module, an analysis module, a regulation module and a drive module.

[0064] The temperature acquisition module receives the real-time temperature signal in the box 1 acquired by the temperature sensor 6, converts the real-time temperature signal into real-time temperature data, and transmits the real-time temperature data to the display module, the analysis module and the adjustment module;

[0065] The display module receives the real-time temperature data transmitted by the temperature acquisition module, converts the temperature data into a display signal, and transmits the display signal to the display screen 18 , which displays the real-time temperature in the box 1 .

[0066] The analysis module receives real-time temperature data. When the real-time temperature data is greater than 24°C or the real-time temperature data is less than 20°C, the difference between the real-time temperature data and 24°C or the absolute value of the difference between the real-time temperature data and 20°C is calculated respectively, and a rotation drive signal with different rotation power of the servo motor 15 is converted according to the difference and the absolute value of the difference, and then the rotation drive signal is transmitted to the drive module. When the real-time temperature is between 20-24°C, the rotation stop drive signal is transmitted to the drive module.

[0067] The regulating module receives real-time temperature data. When the real-time temperature data is greater than 24°C, a cooling drive signal is transmitted to the thermoelectric cooling sheets 5. When the real-time temperature data is less than 20°C, a heating drive signal is transmitted to the thermoelectric cooling sheets 5. When the real-time temperature is between 20-24°C, a regulating stop drive signal is transmitted to the thermoelectric cooling sheets 5.

[0068] The driving module receives the rotation driving signal or the rotation stopping driving signal transmitted by the analyzing module, and transmits the rotation driving signal or the rotation stopping driving signal to the servo motor 15 .

[0069] Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived from these are still within the scope of protection of the invention.

Claims

1. A cryoprecipitation constant temperature storage box for a blood transfusion department, comprising a box body (1) and a box cover (2), wherein the box cover (2) is detachably connected to the box body (1), and a sealing ring is provided at the bottom of the box cover (2), characterized in that: A placement plate (3) is provided inside the box body (1), a hollow connection tube (4) is fixedly connected to the bottom end of the placement plate (3), the bottom end of the connection tube (4) is fixedly connected to the bottom wall of the box body (1), a temperature adjustment chamber is provided outside the connection tube (4), a plurality of thermoelectric cooling sheets (5) are provided in the temperature adjustment chamber, a temperature sensor (6) is fixedly connected to the side wall of the box body (1), the temperature sensor (6) is signal-connected to a control system, and the plurality of thermoelectric cooling sheets (5) are signal-connected to the control system; The control system is used to receive real-time temperature data collected by the temperature sensor (6), and to control a plurality of thermoelectric cooling sheets (5) through signals so that the temperature inside the box (1) is maintained between 20° C. and 24° C.; The inner wall of the box body (1) is provided with a storage and access wall (7) and a drainage wall (8) in sequence from top to bottom. The storage and access wall (7) and the drainage wall (8) are integrally formed with the box body (1). The chamber corresponding to the storage and access wall (7) is the storage and access chamber (701), and the chamber corresponding to the drainage wall (8) is the storage chamber (801). The storage and access wall (7) is provided with symmetrical circulation channels (9). Both ends of the circulation channels (9) are respectively connected to the storage and access chamber (701) and the storage chamber (801). The side wall of the connecting tube (4) is uniformly circumferentially A plurality of through holes (10) are provided, a negative pressure chamber (11) is provided in the placement plate (3), an air flow driving component is provided in the negative pressure chamber (11), a plurality of return air holes (12) are provided on the surface of the placement plate (3), both ends of the return air holes (12) are respectively connected to the negative pressure chamber (11) and the storage chamber (801), when the air flow driving component is started, the air flow in the box body (1) flows in sequence along the path of the through holes (10), the guide wall (8), the circulation channel (9) to the return air holes (12) to form a flow cycle.

2. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 1, characterized in that: The opening direction of the circulation channel (9) connected to one end of the access chamber (701) is directed toward the storage chamber (801), and the airflow in the box body (1) returns to the storage chamber (801) through the circulation channel (9) during the circulation.

3. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 2, characterized in that: The inner wall of the circulation channel (9) is a Venturi tube structure. When medical personnel open the cover to access the blood cryoprecipitate bag, the airflow passes through the circulation channel (9) to form a vortex ring airflow curtain in the access chamber (701).

4. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 3, characterized in that: The airflow driving component comprises a shell (13), the outer wall of the shell (13) is fixedly connected to the inner wall of the negative pressure chamber (11), a rotating blade (14) is rotatably connected inside the shell (13), a servo motor (15) corresponding to the position of the rotating blade (14) is fixedly connected to the bottom wall of the box body (1), and an output shaft of the servo motor (15) passes through the bottom wall of the shell (13) and is coaxially fixedly connected to the rotating blade (14).

5. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 4, characterized in that: The servo motor (15) is connected to the control system signal. The control system adjusts the rotation power of the servo motor (15) according to the temperature of the box (1), so that the driving power of the servo motor (15) is inversely proportional to the difference.

6. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 5, characterized in that: A plurality of thermoelectric cooling sheets (5) are arranged vertically, one end of each thermoelectric cooling sheet (5) is fixedly connected to the connecting tube (4), and the other end of each thermoelectric cooling sheet (5) is fixedly connected to the inner wall of the box body (1), and the gap between adjacent thermoelectric cooling sheets (5) is a temperature adjustment unit, and the position and number of the temperature adjustment units correspond to the position and number of the through holes (10).

7. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 6, characterized in that: The top surface of the placement plate (3) is provided with a plurality of protrusions (16) with a honeycomb structure, and air passages (17) are provided between adjacent protrusions (16).

8. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 7, characterized in that: The protrusions (16) are all made of a paraffin mixture material. When the temperature in the box (1) changes, the protrusions (16) undergo phase change according to the temperature change, releasing or storing latent heat. At the same time, the width of the air passage (17) changes with the phase change expansion of the protrusion (16), and the change in the width of the air passage (17) is proportional to the temperature.

9. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 8, characterized in that: A display screen (18) is inlaid and fixed on the top of the box body (1), and the display screen (18) is connected to the control system signal.

10. The cryoprecipitation constant temperature storage box for blood transfusion department according to claim 9, characterized in that: The control system includes a temperature acquisition module, a display module, an analysis module, a regulation module and a drive module; A temperature acquisition module, used for receiving a real-time temperature signal in the box (1) acquired by a temperature sensor (6), converting the real-time temperature signal into real-time temperature data, and transmitting the real-time temperature data to a display module, an analysis module and an adjustment module; A display module, used for receiving the real-time temperature data transmitted by the temperature acquisition module, converting the temperature data into a display signal, and transmitting the display signal to a display screen (18), so that the display screen (18) displays the real-time temperature inside the box (1); An analysis module is used to receive real-time temperature data, and when the real-time temperature data is greater than 24°C or the real-time temperature data is less than 20°C, the difference between the real-time temperature data and 24°C or the absolute value of the difference between the real-time temperature data and 20°C is calculated, and a rotation drive signal with different rotation powers of the servo motor (15) is converted according to the difference and the absolute value of the difference, and then the rotation drive signal is transmitted to the drive module, and when the real-time temperature is between 20-24°C, a rotation stop drive signal is transmitted to the drive module; The regulating module is used to receive real-time temperature data, and when the real-time temperature data is greater than 24°C, transmit a cooling drive signal to the plurality of thermoelectric cooling sheets (5); when the real-time temperature data is less than 20°C, transmit a heating drive signal to the plurality of thermoelectric cooling sheets (5); and when the real-time temperature is between 20°C and 24°C, transmit a regulating stop drive signal to the plurality of thermoelectric cooling sheets (5); The driving module is used to receive the rotation driving signal or the rotation stopping driving signal transmitted by the analyzing module, and transmit the rotation driving signal or the rotation stopping driving signal to the servo motor (15).

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