Traditional Chinese medicine composition for treating waist and leg pain

Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating waist and leg pain. The traditional Chinese medicine composition comprises ligusticum wallichii, liquorice, notopterygium root, myrrh, safflower carthamus, codonopsis pilosula, angelica sinensis, prepared rehmannia root and the like, and has a good effect on treating waist and leg pain.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating lumbocrural pain. Background Art

[0002] Lumbocrural pain is a common disease in life. Many people choose to take painkillers to relieve pain, but this method only treats the symptoms rather than the root cause. At present, some doctors almost associate lumbocrural pain with lumbar disc herniation and osteoproliferation, showing a tendency of overgeneralization and uniformity. Traditional Chinese medicine treats lumbocrural pain by syndrome differentiation to completely cure the disease, and the same is true for lumbocrural pain.

[0003] It is recorded in "Huangdi Neijing": "When cold qi enters the meridians and stagnates, it cannot flow smoothly. When it lodges outside the vessels, there is less blood; when it lodges inside the vessels, qi cannot pass through, so sudden pain occurs." It also says: "When heat qi stays in the small intestine, there is pain in the intestine, accompanied by heat and thirst, and the stool cannot be discharged smoothly, so pain and obstruction occur." These two sentences illustrate the principle of "pain due to obstruction".

[0004] When cold qi invades the meridians of the human body, the originally smooth qi and blood become stagnant due to cold, and pain occurs due to the unsmooth flow of qi and blood. When various pathogenic factors stay in the body, combine with qi and blood, block the meridians, stagnate in the zang-fu organs, causing qi to be unsmooth, blood to be stagnated, and turbid substances such as phlegm-dampness and feces produced by the body metabolism to stay in the body, all of which can cause pain.

[0005] Meridians are the pathways for the flow of qi and blood. They belong to the zang-fu organs internally, connect to the limbs and joints externally, communicate the interior and exterior, and penetrate the upper and lower parts. If the meridians are invaded by external pathogenic factors and blocked by qi stagnation, stasis, cold, heat and other pathological conditions, various pains will occur, qi and blood will condense, blocking the meridians, and pain occurs due to obstruction.

[0006] Neck, shoulder, lumbocrural pain is a common and frequently-occurring disease in orthopedic clinics, seriously affecting people's physical health and normal work, life, study and labor. At present, there are many drugs for treating lumbocrural pain on the market. Most of the western medicine preparations are analgesic drugs, and hormone drugs are used more frequently, which are very harmful to the human body in the long term. Summary of the Invention

[0007] In view of the above problems, the present invention provides a traditional Chinese medicine composition that can effectively treat lumbocrural pain and is beneficial to the human body.

[0008] The technical solution adopted by the present invention is as follows: A traditional Chinese medicine composition for treating waist and leg pain comprises the following components by weight: 45-55 parts of chuanxiong, 35-50 parts of liquorice, 30-40 parts of notopterygium root, 30-37 parts of myrrh, 25-35 parts of safflower, 20-30 parts of codonopsis pilosula, 20-25 parts of angelica sinensis, 18-30 parts of rehmannia glutinosa, 16-35 parts of angelica pubescens, 13-25 parts of white peony root, 20-40 parts of earthworm, 20-25 parts of cynomorium songaricum, 15-20 parts of morinda officinalis, and 13-18 parts of cinnamon bark.

[0009] Further preferably, the Chinese medicine composition comprises the following components by weight: 45-50 parts of Chuanxiong, 35-40 parts of Licorice, 30-37 parts of Notopterygium, 30-35 parts of Myrrh, 25-30 parts of Carthamus, 20-25 parts of Codonopsis, 20-23 parts of Angelica, 20-25 parts of Rehmannia, 25-30 parts of Angelica dahurica, 20-25 parts of Rehmannia glutinosa, 25-30 parts of Angelica dahurica, 20-25 parts of White Peony Root, 20-30 parts of Pheretima, 20-23 parts of Cynomorium songaricum, 15-18 parts of Morinda officinalis, and 15-18 parts of Cinnamon Bark.

[0010] Still further preferably, the Chinese medicine composition comprises the following components by weight: 48 parts of Chuanxiong, 37 parts of Licorice, 34 parts of Notopterygium, 33 parts of Myrrh, 28 parts of Carthamus, 23 parts of Codonopsis, 22 parts of Angelica, 23 parts of Rehmannia, 28 parts of Angelica dahurica, 23 parts of Rehmannia glutinosa, 28 parts of Angelica dahurica, 23 parts of Pheretima, 23 parts of White Peony Root, 25 parts of Pheretima, 22 parts of Cynomorium songaricum, 17 parts of Morinda officinalis, and 17 parts of Cinnamon Bark.

[0011] Furthermore, the Chinese medicine composition also includes 13 to 18 portions of mistletoe.

[0012] Efficacy of the raw materials of the present invention: Chuanxiong: Chuanxiong was first recorded in Tangye Bencao. It is recorded in Benjing, Tangye Bencao and Pharmacopoeia that Chuanxiong can be used to promote blood circulation and qi, dispel wind and relieve pain, and has certain effects on headache, irregular menstruation, promoting blood circulation and qi, etc. Chuanxiong can reduce the content of dynorphin A in plasma and cerebrospinal fluid caused by cerebral ischemia, improve cerebral ischemic damage, and relieve pulmonary hypertension.

[0013] Licorice: Licorice was first recorded in the book "Er Ya". Its medicinal use was first seen in the "Shennong Bencao Jing" of the Han Dynasty: "It tastes sweet, is flat, and is non-toxic. It can treat cold and heat evil spirits in the five internal organs. It strengthens tendons and bones, and grows muscles. It doubles strength, treats wounds, and detoxifies. Long-term use can make the body lighter and prolong life. It grows in rivers and valleys", and is listed as a top-grade product. The "Famous Doctors' Records" written by the medical expert Tao Hongjing called licorice beautiful grass, honey grass, and national elder, and it is the "king of all medicines", which can "warm the middle and lower the qi, relieve irritability and shortness of breath, and cough caused by damaged organs; quench thirst, dredge meridians, benefit blood and qi, and detoxify hundreds of medicines". Zhen Quan, a famous doctor in the Tang Dynasty, pointed out that licorice can "treat 72 kinds of milk stone poisons and detoxify 1,200 kinds of plant poisons".

[0014] Notopterygium Root: According to the "Compendium of Materia Medica", notopterygium root has the effects of antipyretic and analgesic, antibacterial and anti-inflammatory, anti-arrhythmia and protection against myocardial ischemia, etc. It can be used to treat symptoms such as cold and fever, rheumatoid arthritis, joint and muscle soreness, etc. If the dosage is too much, it is easy to cause vomiting, so it is not suitable for those with weak spleen and stomach. Its rhizome contains volatile oil, coumarin, and in addition, it also contains carbohydrates, amino acids, organic acids, sterols, etc.

[0015] Myrrh: It has a pungent and bitter taste and a neutral nature. It belongs to the heart, liver, and spleen meridians. It is used for the treatment of diseases such as chest impediment pain, epigastric pain, dysmenorrhea and amenorrhea, postpartum stasis obstruction, abdominal pain due to mass, rheumatic arthralgia, traumatic injury, carbuncle and sore.

[0016] Safflower: It has a pungent and bitter taste and a neutral nature. It can disperse stasis and relieve pain, reduce swelling and promote granulation. It is used for the treatment of diseases such as chest impediment pain, epigastric pain, dysmenorrhea and amenorrhea, postpartum stasis obstruction, abdominal pain due to mass, rheumatic arthralgia, traumatic injury, carbuncle and sore.

[0017] Codonopsis Pilosula: Codonopsis pilosula was first recorded in the "New Compendium of Materia Medica" in the Qing Dynasty. It has a sweet taste and a neutral nature; it belongs to the spleen and lung meridians; it has the effects of strengthening the spleen and benefiting the lung, nourishing blood and promoting fluid production. Modern pharmacological research shows that codonopsis pilosula also has various pharmacological effects such as enhancing the body's immunity, protecting the gastrointestinal mucosa and anti-ulcer, promoting hematopoiesis, regulating blood sugar, and delaying aging; at the same time, codonopsis pilosula is also a health product and can be used in diets. [9] Codonopsis pilosula can be made into tea or wine. Brewing it with perilla with boiling water is codonopsis pilosula and perilla tea, which is used for wind-cold cold; putting codonopsis pilosula into white wine is codonopsis pilosula wine.

[0018] Angelica Sinensis: It belongs to the liver, heart, and spleen meridians. It can enrich blood and promote blood circulation, regulate menstruation and relieve pain, moisten the intestines and relieve constipation. It is used for sallow complexion due to blood deficiency, dizziness and palpitations, irregular menstruation, amenorrhea and dysmenorrhea, deficiency-cold abdominal pain, intestinal dryness and constipation, rheumatic arthralgia, traumatic injury, carbuncle and sore. Angelica sinensis processed with wine promotes blood circulation and dredges the meridians. It is used for amenorrhea and dysmenorrhea, rheumatic arthralgia, traumatic injury.

[0019] Prepared Rehmannia Root: It is sweet and slightly warm. "New Compendium of Materia Medica": It nourishes the kidney water, fills the bone marrow, promotes blood circulation, tonifies the true yin, improves hearing and eyesight, makes hair black. It can also tonify the spleen yin, stop chronic diarrhea, treat wind-cold arthralgia, yin deficiency fever, dry cough with phlegm, shortness of breath and asthma, feeling of emptiness and hunger in the stomach, no pus in the pox syndrome due to deficiency of heart qi, soreness of the shins and thighs after illness, acute pain in the umbilical and abdominal regions after childbirth, yin deficiency in the syndrome of infection, constipation without sweating, various types of bleeding, all kinds of deficiency and damage diseases due to yin deficiency of the liver and kidney. It is the main drug for nourishing yin.

[0020] Angelica Pubescens: Recorded in the "Supplementary Records of Famous Physicians": "It has a sweet taste, is slightly warm, and is non-toxic. It mainly treats various pathogenic winds and gout of all joints, regardless of whether it is new or old." It also has the effects of expelling wind and dampness, dispersing cold and relieving pain, and is mainly used to treat symptoms such as wind-cold-damp arthralgia, lumbar and knee pain, headache and toothache.

[0021] White peony root: Medicinal root, pungent and bitter; slightly toxic; with the effects of warming yang and removing dampness, replenishing body deficiency, and strengthening spleen and stomach. White peony root is used in folk medicine to treat rheumatism, cold pain, rheumatoid arthritis, lumbar muscle strain, physical weakness, limb convulsions, slow convulsions, dog bites and other diseases.

[0022] Earthworms: Earthworms are among the 67 kinds of animal medicines recorded in the Chinese medicine monograph "Shennong's Herbal Classic". It is listed as a low-grade product in "Shennong's Herbal Classic". It has the effects of clearing away heat and calming the nerves, unblocking the meridians, calming asthma, and diuresis. It is often used for high fever, coma, convulsions, joint pain, lung heat cough, oliguria, edema, hypertension, etc. after being stir-fried. It mainly contains a variety of amino acids. Because the raw product has a strong fishy smell, it is generally fried before being used as medicine. Tao Hongjing said: "If you take dried earthworms, you must boil them into crumbs." There are many ways to prepare earthworms in traditional Chinese medicine, mainly medicine, vinegar, boiling, wine, oil, clam powder frying, salt, etc., to make it loose, crispy, detoxified, correct the smell, and easy to decoct and take.

[0023] Cynomorium songaricum: The "Compendium of Materia Medica" records that Cynomorium songaricum "replenishes essence and invigorates Yang, moisturizes dryness and nourishes tendons, treats impotence, and lubricates the large intestine. It should be avoided by those with diarrhea and those whose Yang is easily erected but whose essence is not solid". Cynomorium songaricum is known as the "elixir of life". Throughout the dynasties, Cynomorium songaricum has been used to nourish the kidney and Yang to consolidate essence and stop nocturnal emission. It has been used to treat male nocturnal emission and infertility, female infertility and constipation.

[0024] Morinda officinalis: Morinda officinalis is a precious Chinese medicinal material, one of the "four major southern medicines". There is a saying among the people that "there is ginseng in the north and Morinda officinalis in the south". It is mainly used to treat impotence and spermatorrhea, uterine coldness and infertility, irregular menstruation, cold pain in the lower abdomen, rheumatic pain, and weakness of tendons and bones.

[0025] Cinnamon: According to the Compendium of Materia Medica, cinnamon has the effects of warming the middle and tonifying the kidney, dispelling cold and relieving pain. It is mainly used to treat cold pain in the waist and knees, stomach pain due to deficiency and cold, chronic indigestion, abdominal pain, vomiting and diarrhea, amenorrhea caused by cold and other diseases.

[0026] Mistletoe: The original plant of the mulberry parasite recorded in "Compendium of Materia Medica", that is, the authentic Chinese medicinal material Miscanthus; the whole plant is used as medicine, which has the effects of treating rheumatism, low back pain, fetal movement, and fetal leakage. Beneficial Effects

[0027] This Chinese medicine composition has the effects of nourishing blood and relaxing muscles, dispelling wind and dampness, can be used to improve symptoms such as soreness of waist and knees, pain, and difficulty in flexion and extension, and has a conditioning effect on nerve compression caused by lumbar disc herniation. Secondly, it has the effects of replenishing fire and supporting yang, dispelling cold and relieving pain, and warming and unblocking meridians. It has a certain relieving effect on soreness and weakness of waist and knees caused by kidney yang deficiency, as well as pain in waist and legs. At the same time, it has the effects of promoting blood circulation and unblocking meridians, dispersing blood stasis and relieving pain, so as to achieve the purpose of promoting qi and blood circulation, unblocking meridians, removing blood stasis and relieving pain, clearing away dampness and heat, unblocking meridians and relieving pain, and using mistletoe for addition and subtraction to achieve the purpose of warming the meridians, dispersing cold, removing dampness and unblocking meridians, thereby effectively treating pain in waist and legs. DETAILED DESCRIPTION

[0028] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be described clearly and completely below. For those not specified in the embodiments, they are carried out according to conventional conditions or conditions recommended by the manufacturer. For reagents or instruments not specified by the manufacturer, they are all conventional products that can be obtained through commercial purchase.

[0029] It should be noted that, without conflict, the embodiments in this application and the features in the embodiments can be combined with each other. The present invention will be described in detail below with reference to specific embodiments. Example 1

[0030] A traditional Chinese medicine composition for treating lumbocrural pain, which comprises the following components by weight: 45 parts of Ligusticum chuanxiong, 35 parts of Glycyrrhiza uralensis, 30 parts of Notopterygium incisum, 30 parts of Myrrha, 25 parts of Carthamus tinctorius, 20 parts of Codonopsis pilosula, 20 parts of Angelica sinensis, 18 parts of Rehmannia glutinosa, 16 parts of Heracleum hemsleyanum, 13 parts of Paeonia lactiflora, 20 parts of Pheretima aspergillum, 2 parts of Cynomorium songaricum, 15 parts of Morinda officinalis, 13 parts of Cinnamomum cassia. Example 2

[0031] A traditional Chinese medicine composition for treating lumbocrural pain, which comprises the following components by weight: 55 parts of Ligusticum chuanxiong, 50 parts of Glycyrrhiza uralensis, 40 parts of Notopterygium incisum, 37 parts of Myrrha, 35 parts of Carthamus tinctorius, 30 parts of Codonopsis pilosula, 25 parts of Angelica sinensis, 30 parts of Rehmannia glutinosa, 35 parts of Heracleum hemsleyanum, 25 parts of Paeonia lactiflora, 40 parts of Pheretima aspergillum, 25 parts of Cynomorium songaricum, 20 parts of Morinda officinalis, 18 parts of Cinnamomum cassia. Example 3

[0032] A traditional Chinese medicine composition for treating lumbocrural pain, which comprises the following components by weight: 47 parts of Ligusticum chuanxiong, 39 parts of Glycyrrhiza uralensis, 37 parts of Notopterygium incisum, 33 parts of Myrrha, 29 parts of Carthamus tinctorius, 26 parts of Codonopsis pilosula, 23 parts of Angelica sinensis, 19 parts of Rehmannia glutinosa, 22 parts of Heracleum hemsleyanum, 17 parts of Paeonia lactiflora, 28 parts of Pheretima aspergillum, 23 parts of Cynomorium songaricum, 18 parts of Morinda officinalis, 16 parts of Cinnamomum cassia. Example 4

[0033] A traditional Chinese medicine composition for treating lumbocrural pain, which comprises the following components by weight: 48 parts of Ligusticum chuanxiong, 37 parts of Glycyrrhiza uralensis, 34 parts of Notopterygium incisum, 33 parts of Myrrha, 28 parts of Carthamus tinctorius, 23 parts of Codonopsis pilosula, 22 parts of Angelica sinensis, 23 parts of Rehmannia glutinosa, 28 parts of Heracleum hemsleyanum, 23 parts of Paeonia lactiflora, 25 parts of Pheretima aspergillum, 22 parts of Cynomorium songaricum, 17 parts of Morinda officinalis, 17 parts of Cinnamomum cassia.

[0034] Examples 5 - 8 Basically the same as Examples 1 - 4, the only difference is that 15 parts of Taxillus chinensis are added.

[0035] Respectively take the traditional Chinese medicine compositions in Examples 1 to 8, and mix them with 10 to 15 times the weight of water of the taken compositions. Boil them at 80 to 90 °C for 10 h, then add 3 times the amount of water, raise the temperature to 100 °C, and boil for 3 h. Filter to obtain a traditional Chinese medicine decoction suitable for treating lumbocrural pain.

[0036] After solicitation and screening, a total of 160 volunteers with lumbocrural pain were selected and divided into 8 groups, with 20 people in each group. Each group had those with severe, moderate, and mild pain. Among them, there were 6 people with severe pain, 6 people with moderate pain, and 8 people with mild pain in each group. They were divided into experimental groups 1 to 8, and each group used the traditional Chinese medicine decoction prepared from the corresponding traditional Chinese medicine compositions in Examples 1 to 8, 60 mL per person per day, twice a day, for 1 month. The usage results are as follows: The traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition in Example 1 used in experimental group 1: Among them, those with mild symptoms completely disappeared, reaching the cure standard. Among those with moderate symptoms, 5 were cured, 1 became mild, among those with severe symptoms, 3 were cured, 2 became moderate, and 1 became mild.

[0037] The traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition in Example 2 used in experimental group 2: Among them, those with mild symptoms completely disappeared, reaching the cure standard. Among those with moderate symptoms, 6 were cured, among those with severe symptoms, 2 were cured, 3 became moderate, and 1 became mild.

[0038] The traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition in Example 3 used in experimental group 3: Among them, those with mild symptoms completely disappeared, reaching the cure standard. Among those with moderate symptoms, 5 were cured, 1 became mild, among those with severe symptoms, 3 were cured, 1 became moderate, and 2 became mild.

[0039] The traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition in Example 4 used in experimental group 4: Among them, those with mild symptoms completely disappeared, reaching the cure standard. Among those with moderate symptoms, 6 were cured, among those with severe symptoms, 4 were cured, 1 became moderate, and 1 became mild.

[0040] The traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition in Example 5 used in experimental group 5: Among them, those with mild symptoms completely disappeared, reaching the cure standard. Among those with moderate symptoms, 5 were cured, 1 became mild, among those with severe symptoms, 4 were cured, 1 became moderate, and 1 became mild.

[0041] The traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition in Example 6 used in experimental group 6: Among them, those with mild symptoms completely disappeared, reaching the cure standard. Among those with moderate symptoms, 5 were cured, 1 became mild, among those with severe symptoms, 3 were cured, 2 became moderate, and 1 became mild.

[0042] The traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition in Example 7 used in experimental group 7: Among them, those with mild symptoms completely disappeared, reaching the cure standard. Among those with moderate symptoms, 6 were cured, among those with severe symptoms, 4 were cured, 1 became moderate, and 1 became mild.

[0043] The traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition of Example 8 used in Experimental Group 8: Among them, the complete disappearance of mild symptoms reached the cure standard, 6 people with moderate symptoms were cured, 5 people with severe symptoms were cured, and 1 person turned into mild symptoms.

[0044] In summary, the traditional Chinese medicine combination of this application has good effects in treating lumbocrural pain.

[0045] Although the present invention has been described in detail with general descriptions and specific embodiments above, based on the present invention, some modifications or improvements can be made, which are obvious to those skilled in the art. Therefore, these modifications or improvements made without departing from the spirit of the present invention all fall within the scope of protection required by the present invention.

Claims

1. A traditional Chinese medicine composition for treating lumbocrural pain, characterized in that, the traditional Chinese medicine composition comprises the following components by weight parts: 45 - 55 parts of Ligusticum chuanxiong, 35 - 50 parts of Glycyrrhiza uralensis Fisch., 30 - 40 parts of Notopterygium incisum Ting ex H. T. Chang, 30 - 37 parts of Myrrha, 25 - 35 parts of Carthamus tinctorius L., 25 - 30 parts of Ligusticum chuanxiong, 20 - 30 parts of Codonopsis pilosula (Franch.) Nannf., 20 - 25 parts of Angelica sinensis (Oliv.) Diels, 18 - 30 parts of Rehmannia glutinosa Libosch., 16 - 35 parts of Heracleum hemsleyanum Diels, 13 - 25 parts of Paeonia lactiflora Pall., 20 - 40 parts of Pheretima aspergillum (E. Perrier), 20 - 25 parts of Cynomorium songaricum Rupr., 15 - 20 parts of Morinda officinalis How, 13 - 18 parts of Cinnamomum cassia Presl.

2. The traditional Chinese medicine composition for treating lumbocrural pain according to claim 1, characterized in that, the traditional Chinese medicine composition comprises the following components by weight parts: 45 - 50 parts of Ligusticum chuanxiong, 35 - 40 parts of Glycyrrhiza uralensis Fisch., 30 - 37 parts of Notopterygium incisum Ting ex H. T. Chang, 30 - 35 parts of Myrrha, 25 - 30 parts of Carthamus tinctorius L., 20 - 25 parts of Codonopsis pilosula (Franch.) Nannf., 20 - 23 parts of Angelica sinensis (Oliv.) Diels, 20 - 25 parts of Rehmannia glutinosa Libosch., 25 - 30 parts of Heracleum hemsleyanum Diels, 20 - 25 parts of Paeonia lactiflora Pall., 20 - 30 parts of Pheretima aspergillum (E. Perrier), 20 - 23 parts of Cynomorium songaricum Rupr., 15 - 18 parts of Morinda officinalis How, 15 - 18 parts of Cinnamomum cassia Presl.

3. The traditional Chinese medicine composition for treating lumbocrural pain according to claim 2, characterized in that, the traditional Chinese medicine composition comprises the following components by weight parts: 48 parts of Ligusticum chuanxiong, 37 parts of Glycyrrhiza uralensis Fisch., 34 parts of Notopterygium incisum Ting ex H. T. Chang, 33 parts of Myrrha, 28 parts of Carthamus tinctorius L., 23 parts of Codonopsis pilosula (Franch.) Nannf., 22 parts of Angelica sinensis (Oliv.) Diels, 23 parts of Rehmannia glutinosa Libosch., 28 parts of Heracleum hemsleyanum Diels, 23 parts of Paeonia lactiflora Pall., 25 parts of Pheretima aspergillum (E. Perrier), 22 parts of Cynomorium songaricum Rupr., 17 parts of Morinda officinalis How, 17 parts of Cinnamomum cassia Presl.

4. The traditional Chinese medicine composition for treating lumbocrural pain according to claim 1, characterized in that, the traditional Chinese medicine composition further comprises 13 - 18 parts of Taxillus chinensis (DC.) Danser.