Hard candy capable of clearing and nourishing throat and preparation method of hard candy
By using cough-relieving and phlegm-relieving compositions with ingredients such as orange peel and honeysuckle, hard candies for clearing throat and soothing throat and phlegm-relieving tea, the problem that existing throat-relieving products are difficult to take into account both the smell, taste and efficacy, and effective improvement and treatment of various throat discomfort symptoms are achieved, while also having good sensory effects.
Patent Information
- Application Number
- CN202510189035.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2020-12-30
- Publication Date
- 2025-05-30
AI Technical Summary
Existing throat products are difficult to take into account both the smell, taste and efficacy, which leads to restrictions in actual applications.
Provide a cough-relieving composition, including orange peel, honeysuckle, mint, forsythia leaves, reed roots, platycodon, fat sea, lily, harbor fruit and bitter almonds. By preparing hard candies for clearing throat and soothing throat and relieving phlegm alternative tea, it can improve and treat sore throat or itchy throat, dry cough, phlegm cough, and excessive phlegm caused by various reasons.
This composition has more effective improvement and treatment effects on sore throat or itchy throat, dry cough, phlegm cough, excessive phlegm caused by various reasons, and has a good appearance, smell, color, tissue state and taste.
Smart Images
Figure BDA0005279429930000061 
Figure BDA0005279429930000071
Abstract
Description
[0001] This application is a divisional application of the patent application No. 202011617060.X. The filing date of the original application is December 30, 2020, and the invention title is an antitussive and expectorant composition, substitute tea, candy and preparation method. Technical Field
[0002] The present invention relates to the technical field of antitussive and expectorant products, and particularly relates to a throat-soothing hard candy and a preparation method thereof. Background Art
[0003] The oral cavity and pharynx are the first gateway of the respiratory system and are vulnerable and easily damaged parts. Staying up late, diet or stimulation of tobacco, alcohol, large mental stress, emotional excitement and other reasons are likely to cause metabolic disorders and decreased immunity in the body, enabling pathogenic microorganisms to take advantage of the weakness and induce acute pharyngitis. Especially on smoggy days, nasal hairs can only block large particles, but small particles, such as PM2.5, will still reach the pharynx, and these small particles carry harmful viruses, bacteria, heavy metals, etc., which can cause or exacerbate pharyngeal lesions, presenting symptoms such as dry itching, pain, and foreign body sensation in the throat, and will directly enter the human alveoli, not only directly triggering respiratory diseases and causing cough, but also causing long-term and potential health damage. Especially for patients with respiratory diseases such as pharyngitis and pneumonia, a part of the fine particles in the smog will adhere to the pharynx and aggravate the discomfort in the pharynx. At the same time, the smog also contains a lot of bacteria, viruses and a large amount of acidic and alkaline substances, which not only irritate the throat, but also damage the respiratory mucosa, leading to upper respiratory tract infections, presenting symptoms such as pharyngeal inflammation, swelling, pain, congestion, etc., and even further leading to diseases such as acute upper respiratory tract infection, acute pharyngitis, and acute exacerbation of chronic pharyngitis. In addition to smog, smoking or second-hand smoke, automobile exhaust, industrial waste gas, etc. will also cause harm to the throat and lungs, causing cough and pharyngeal discomfort.
[0004] Products such as substitute tea and throat lozenges are commonly used throat-soothing products, but products such as substitute tea and throat lozenges with expectorant and antitussive effects often have poor smell and taste, while products with good smell and taste are difficult to take into account the curative effect, so related products are subject to certain limitations in practical applications. Summary of the Invention
[0005] Aiming at the problem that current throat-soothing products are difficult to take into account smell, taste and curative effect, the present invention provides a throat-soothing hard candy and a preparation method thereof. This hard candy has a more effective improvement and treatment effect on throat swelling and pain, dry itching, dry cough, productive cough, excessive phlegm and other conditions caused by various reasons, and has good appearance, smell, color, tissue state and taste.
[0006] To achieve the above invention purpose, the embodiments of the present invention adopt the following technical solutions:
[0007] On the one hand, an embodiment of the present invention provides an antitussive and expectorant composition, comprising the following components in parts by weight: 4.5 - 6.5 parts of tangerine peel, 4.5 - 6.5 parts of honeysuckle flower, 5 - 6 parts of mint, 3.5 - 4.5 parts of forsythia leaf, 3 - 4 parts of reed root, 1.5 - 2.5 parts of platycodon root, 0.8 - 1.3 parts of boat-fruited sterculia seed, 0.8 - 1.3 parts of lily bulb, 0.5 - 1.5 parts of monk fruit, and 0.8 - 1.3 parts of bitter apricot kernel.
[0008] In this antitussive and expectorant composition, tangerine peel is pungent, bitter, and warm in nature, enters the spleen and lung meridians, regulates qi, harmonizes the middle, dries dampness, and can promote the secretion of respiratory mucosa, relieve bronchospasm, and play roles in reducing phlegm, relieving cough, and relieving asthma.
[0009] Honeysuckle flower is sweet, cold in nature, and belongs to the lung and stomach meridians. It clears heat and reduces fire, disperses wind-heat, cools blood and stops dysentery, detumescence and detoxification, and can enhance the body's immune ability and inhibit the invasion of viruses.
[0010] Mint is pungent, cool in nature, and belongs to the lung and liver meridians, with the effects of inducing sweating and relieving fever, soothing the liver and regulating qi, clearing the head and eyes, relieving sore throat and pain, and relieving itching.
[0011] Forsythia leaf is bitter, cold in nature, and belongs to the heart and lung meridians. It has the effects of clearing heat and detoxifying, detumescence and pain relief, anti-inflammatory and antibacterial, and can inhibit the reproduction of pathogenic bacteria.
[0012] Reed root is sweet, cold in nature, and belongs to the lung and stomach meridians. It is good at clearing and purging the excess heat in the qi aspect of the lung and stomach, and can also promote the production of body fluid to quench thirst, relieve restlessness, and stop vomiting.
[0013] Platycodon root is bitter, pungent, neutral in nature, enters the lung meridian, pungent for promoting qi movement and bitter for purging, with the property of ascending and floating. It can ventilate and disperse the deficiency of lung qi, reduce phlegm and drain pus, clear and purge the throat, and relieve cough and reduce phlegm. For the syndrome of cough with phlegm, whether it is due to cold or heat in the lung, it can be used.
[0014] Boat-fruited sterculia seed is sweet, cold in nature, and belongs to the lung and large intestine meridians, with the effects of clearing and dispersing lung qi, clearing and moistening the lung, relieving sore throat, and restoring voice. It can be used for hoarseness due to lung heat, dry cough without phlegm, and dry and painful throat, and has a good effect on clearing lung heat and moistening lung dryness.
[0015] Lily bulb is sweet, cold in nature, and belongs to the heart and lung meridians, with the effects of nourishing yin and clearing heat, moistening the lung and relieving cough, calming the mind and relieving uneasiness, nourishing essence and blood, regulating the spleen and stomach.
[0016] Monk fruit is sweet, cool in nature, and belongs to the lung, spleen, and large intestine meridians. It can clear lung heat, moisten lung dryness, relieve sore throat, promote the production of body fluid and moisten the intestine, reduce phlegm and relieve cough, loosen the bowels and relieve constipation, and also has the effects of enhancing immunity, anti-fatigue, anti-hypoxia, and antibacterial.
[0017] Bitter apricot kernel is bitter, slightly warm in nature, and belongs to the lung and large intestine meridians, with the effects of lowering qi, relieving cough and asthma, tonifying the lung, and loosening the bowels.
[0018] In this cough-relieving and phlegm-dissipating composition, honeysuckle is good at clearing heat and detoxifying, and can treat sore throats, serving as the sovereign drug. Peppermint can clear and benefit the throat, and together with honeysuckle, they act as the sovereign drugs to achieve the effects of clearing heat and detoxifying, and relieving the throat. Tangerine peel is good at drying dampness and resolving phlegm, and is a key drug for treating damp phlegm and cold phlegm. It plays the role of resolving phlegm in this formula and serves as the ministerial drug. Forsythia leaf and honeysuckle in combination can assist honeysuckle in clearing heat and detoxifying, so it is used together with tangerine peel as the ministerial drug. Reed root can clear heat and purge fire, promote the production of body fluid and quench thirst. Platycodon grandiflorum can disperse the lung qi and expel pathogenic factors to benefit the throat. Sterculia lychnophora can moisten the lung and resolve phlegm, and relieve sore throat and voice hoarseness. Momordica grosvenori can clear heat and moisten the lung, and relieve sore throat and voice hoarseness. The four are used together as the assistant drugs to achieve the effects of moistening the lung and resolving phlegm, and clearing and moistening the throat. Lily nourishes yin and moistens the lung to relieve cough, and bitter apricot kernel nourishes yin and moistens the lung, moistens dryness and relieves cough. The two are used together as the envoy drug. Most of the ingredients in the whole formula are mainly those that clear heat and detoxify, moisten the lung and relieve cough, and relieve sore throat and voice hoarseness, achieving the effects of clearing and moistening the throat, clearing heat and detoxifying, and purging the lung qi.
[0019] Meanwhile, this cough-relieving and phlegm-dissipating composition has good appearance, smell, color, texture and taste. The substitute tea and candies made from it can both have good sensory effects while effectively relieving cough and dissipating phlegm, and clearing and moistening the throat.
[0020] This composition can be brewed and taken in the form of substitute tea, or made into oral products such as lozenges and candies.
[0021] Preferably, the composition includes the following components in parts by weight: 5 - 6 parts of tangerine peel, 5 - 6 parts of honeysuckle, 5.3 - 5.7 parts of peppermint, 3.5 - 4 parts of forsythia leaf, 3 - 3.5 parts of reed root, 1.8 - 2.2 parts of platycodon grandiflorum, 1 - 1.2 parts of sterculia lychnophora, 1 - 1.2 parts of lily, 0.8 - 1.2 parts of momordica grosvenori, and 1 - 1.2 parts of bitter apricot kernel.
[0022] Preferably, the composition includes the following components in parts by weight: 5.5 parts of tangerine peel, 5.5 parts of honeysuckle, 5.5 parts of peppermint, 4 parts of forsythia leaf, 3.5 parts of reed root, 2 parts of platycodon grandiflorum, 1 part of sterculia lychnophora, 1 part of lily, 1 part of momordica grosvenori, and 1 part of bitter apricot kernel. When the above components of this composition are in this ratio, it has a more effective improvement and treatment effect on sore throats, dryness or itching in the throat, dry cough, productive cough, excessive phlegm, etc. caused by various reasons, and has a better sensory effect.
[0023] In a second aspect, the embodiments of the present invention also provide the application of the above composition in the preparation of cough-relieving and phlegm-dissipating products.
[0024] The above composition has a quick onset, high cure rate, and no side effects for symptoms such as sore throat, dry cough, productive cough, excessive phlegm, etc., and can be used to prepare various forms of phlegm-dissipating and cough-relieving products, such as powder, substitute tea, lozenges, sprays, candies, etc.
[0025] In a third aspect, the present invention also provides a substitute tea for relieving cough and reducing phlegm, the raw materials of which include the above-mentioned cough and reducing phlegm composition. The substitute tea is easy to carry and use, and can prevent and relieve symptoms such as cough, excessive phlegm, and throat discomfort caused by various reasons by daily brewing and drinking.
[0026] Preferably, the preparation process of the cough relieving and phlegm reducing substitute tea is:
[0027] Weigh the components of the cough-relieving and phlegm-reducing composition according to weight, dry them to a moisture content of ≤3.0% respectively, and grind them to obtain orange peel powder, honeysuckle powder, mint powder, forsythia leaf powder, reed root powder, platycodon powder, sterculia lychnophora powder, lily powder, monk fruit powder and bitter almond powder; components with a moisture content of ≤3.0% do not need to be dried and can be directly grinded;
[0028] The honeysuckle powder, forsythia leaf powder, reed root powder, platycodon powder, sterculia lychnophora powder, lily powder, monk fruit powder and bitter almond powder are mixed, dry granulated, the orange peel powder and mint powder are added, mixed and sterilized by ultraviolet light to obtain the product.
[0029] The dry granulation process ensures the drug ratio of the original formula to the greatest extent and has the advantage of reducing the formulation.
[0030] Drying can be done by microwave drying.
[0031] Dry granulation can first be carried out by using a vacuum pressure rod twin screw extrusion granulator for granulation, and then the granulation is crushed by a roller crusher, sieved, and the coarse particles and fine powder are granulated again by using a vacuum pressure rod twin screw extrusion granulator, and the granulation is crushed by a roller crusher. This granulation method is different from the traditional dry granulation. Instead, it uses the method of first extrusion and then crushing. The coarse particles and fine powder contained in the particles obtained after the above-mentioned powders of each component are granulated and crushed twice are very small. They can be retained in actual production, or they can be screened out according to product requirements. The impact on the raw material ratio is minimal, and it will hardly affect the product efficacy and taste. The granulation mesh number is preferably 18 to 22 meshes. After crushing, an electric sieve can be used to sieve out particles with a fineness of 20 to 40 meshes, and the obtained fine powder and large particles with a particle size greater than 20 meshes are granulated again. The present invention has found in the research that the above raw material powder can avoid the uneven particles that occur in the actual production of conventional dry granulation or one-time granulation (only one granulation and crushing) as much as possible by using this process, and the precipitation efficiency is more than 3 times the precipitation efficiency of conventional dry granulation or one-time granulation process. At the same time, the obtained particles can increase the volumetric efficiency of tea bags by about 10% compared with the fine powder without granulation. The volumetric rate of the raw materials that have only been granulated once is only 90% of that of normal raw materials, and because the particles are coarse, the filter paper cannot be controlled to be crushed during production, resulting in broken bags, leaking bags, etc. The advantages of reciprocating granulation in tea bags are large formula capacity, more precipitated substances, and easy absorption.
[0032] Fourthly, the embodiment of the present invention also provides a throat-soothing hard candy, the raw materials of which include the dried powder of the water extract of the above cough-relieving and phlegm-removing composition.
[0033] Preferably, the preparation process of the dried powder of the water extract is as follows:
[0034] Weigh each component of the cough-relieving and phlegm-removing composition according to parts by weight, extract with 10-16 times the total mass of the cough-relieving and phlegm-removing composition with water for 2-3 times, 1-2 hours each time, combine and concentrate the obtained extraction liquid, and spray-dry to obtain the dried powder of the water extract. The paste yield of the obtained extraction liquid and the polysaccharide content in the obtained dried powder of the composition are both relatively high under this extraction method.
[0035] Preferably, the raw materials of the throat-soothing hard candy further include isomaltitol, a sweetening agent, and a food flavor. The sweetening agent can be selected from at least one of sucralose, aspartame, acesulfame potassium, and steviol glycoside.
[0036] The mass ratio of the dried powder of the water extract, isomaltitol, the sweetening agent, and the food flavor is (0.1-1.0):(97-99):(0.01-0.06):(0.3-1.5);
[0037] The preparation process of the throat-soothing hard candy is as follows:
[0038] Weigh the isomaltitol, add water equivalent to 25-35% of its mass, heat to dissolve all the isomaltitol at 0.4-0.5 MPa and 105-110 °C, and boil the sugar at 0.8-0.9 MPa and 160-165 °C until the water content drops below 2% by mass;
[0039] When the temperature of the sugar solution reaches 130-140 °C, add the dried powder of the water extract, the sweetening agent, and the food flavor, mix evenly, pour into a mold, and cool and dry to obtain the throat-soothing hard candy.
[0040] This preparation process adopts a vacuum boiling process, which can reduce the boiling point of the sugar solution, reduce the decomposition and change of sugar, make the obtained sugar cubes light in color, correct in flavor, and have good storage stability. Specific Embodiments
[0041] In order to make the objectives, technical solutions, and advantages of the present invention clearer, the following further describes the present invention in detail with reference to specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.
[0042] The experimental methods used in the following examples are all conventional methods in the art unless otherwise specified.
[0043] The tangerine peel (i.e., dried tangerine peel), honeysuckle flower, mint, reed rhizome, platycodon root, boat-fruited sterculia seed, lily bulb, monk fruit, and bitter apricot kernel used in the following examples all comply with the relevant provisions under each medicinal material item in Part I of the Chinese Pharmacopoeia (2015 Edition); forsythia leaf should comply with the provisions of each item in the text of DBS14 / 001-2017 Local Food Safety Standard Forsythia Leaf.
[0044] The raw materials, reagents, etc. used in the following examples are all obtained from commercial channels unless otherwise specified.
[0045] Examples 1-9
[0046] The embodiments of the present invention provide a cough-relieving and phlegm-dissolving composition, and each embodiment includes the following raw materials in the weight part ratios shown in Table 1:
[0047] Table 1 Cough-relieving and phlegm-dissolving composition of Examples 1-9
[0048]
[0049]
[0050] Example 10
[0051] The embodiments of the present invention provide a cough-relieving and phlegm-dissolving substitute tea, and the raw material is the cough-relieving and phlegm-dissolving composition of Example 1. The preparation process is as follows:
[0052] (1) Select the tangerine peel, honeysuckle flower, mint, forsythia leaf, reed rhizome, platycodon root, boat-fruited sterculia seed, lily bulb, monk fruit, and bitter apricot kernel, and remove impurities and inferior-quality raw materials. Weigh each of the selected raw materials according to the weight parts of the cough-relieving and phlegm-dissolving composition in Example 1;
[0053] (2) Use a microwave dryer to dry each raw material to a moisture content of ≤3%;
[0054] (3) Grind the dried raw materials separately through a 100-mesh sieve to obtain tangerine peel powder, honeysuckle flower powder, mint powder, forsythia leaf powder, reed rhizome powder, platycodon root powder, boat-fruited sterculia seed powder, lily bulb powder, monk fruit powder, and bitter apricot kernel powder;
[0055] (4) Mix the honeysuckle flower powder, forsythia leaf powder, reed rhizome powder, platycodon root powder, boat-fruited sterculia seed powder, lily bulb powder, monk fruit powder, and bitter apricot kernel powder with a mixer, and use a vacuum pressure rod twin-screw extrusion granulator to make granules of about 20 mesh, and use a roller crusher to crush the granules;
[0056] (5) Use an electric sieve to screen the crushed particles, screen out particles with a fineness of 20 - 40 mesh, mix the coarse particles and fine powder outside the range of 20 - 40 mesh evenly again, and use a vacuum pressure rod twin-screw extrusion granulator and a roller crusher to make particles of about 20 mesh again. Mix the products obtained from the two granulations, add the orange peel powder and mint powder, mix them evenly, and irradiate with ultraviolet light for 30 min for sterilization.
[0057] (6) Package using a double-piece packaging machine.
[0058] Example 11
[0059] The embodiment of the present invention provides a throat-soothing hard candy, the raw materials of which are the dried powder of the water extract of the cough-relieving and phlegm-reducing composition in Example 1, isomaltulose, sucralose, and food flavor. The mass ratio of the dried powder of the water extract, isomaltulose, sucralose, and food flavor is 0.5:98:0.03:0.9.
[0060] The preparation process of the dried powder of the water extract is as follows:
[0061] Extract with 10 times the total mass of water of the cough-relieving and phlegm-reducing composition for 3 times, 1 hour each time. After filtering the extraction liquid, combine and concentrate it, and concentrate it under reduced pressure (temperature 60 - 80 °C, vacuum degree 0.04 - 0.08 MPa) to a relative density of 1.07 (measured at 60 °C), and filter with a 300-mesh sieve to obtain a concentrated liquid. Dry the concentrated liquid under the conditions of an inlet air temperature of 170 ± 5 °C and an outlet air temperature of 80 ± 5 °C to obtain the dried powder of the water extract.
[0062] The preparation process of the throat-soothing hard candy is as follows:
[0063] (1) Weigh isomaltulose and place it in a sugar melting pot, and add water equivalent to 30% of its mass;
[0064] (2) Open the steam of the sugar melting pot and heat until all the sugar materials are melted; during the sugar melting process, the air pressure is maintained at 0.4 - 0.5 MPa, and the temperature is controlled at 105 - 110 °C;
[0065] (3) Send the melted sugar liquid to a vacuum continuous sugar boiling pot for boiling; the preheating steam pressure is controlled between 0.4 - 0.5 MPa, the sugar boiling steam pressure is controlled between 0.8 - 0.9 MPa, and the sugar boiling temperature is controlled at 160 - 165 °C;
[0066] (4) Wait for the above sugar liquid to cool to 130 - 140 °C, add the dried powder, sucralose, and food flavor, and stir evenly;
[0067] (5) Use a molding machine to pour and mold the hard candy;
[0068] (6) The molded sugar blocks enter a low-temperature drying room for cooling and drying to obtain the product.
[0069] Example 12
[0070] An embodiment of the present invention provides a hard candy for clearing the throat and moistening the larynx, the raw materials of which are the dried powder of the water extract of the cough-relieving and phlegm-reducing composition of Example 1, isomaltulose, sucralose, and food flavor. The mass ratio of the dried powder of the water extract, isomaltulose, sucralose, and food flavor is 0.1:99:0.01:0.3.
[0071] The preparation process of the dried powder of the water extract is as follows:
[0072] Extract with 16 times the total mass of the cough-relieving and phlegm-reducing composition of water for 3 times, 2 hours each time. After filtering the extract, combine and concentrate it, and concentrate it under reduced pressure (temperature 60 - 80°C, vacuum degree 0.04 - 0.08 MPa) to a relative density of 1.05 (measured at 60°C), and filter with 300 meshes to obtain a concentrated solution. Dry the concentrated solution at an inlet air temperature of 170 ± 5°C and an outlet air temperature of 80 ± 5°C to obtain the dried powder of the composition.
[0073] The preparation process of this hard candy for clearing the throat and moistening the larynx is the same as that of Example 11.
[0074] Example 13
[0075] An embodiment of the present invention provides a hard candy for clearing the throat and moistening the larynx, the raw materials of which are the dried powder of the water extract of the cough-relieving and phlegm-reducing composition of Example 1, isomaltulose, sucralose, and food flavor. The mass ratio of the dried powder of the water extract, isomaltulose, sucralose, and food flavor is 1.0:97:0.06:1.5. The preparation process is as follows:
[0076] The preparation process of the dried powder of the water extract is as follows:
[0077] Extract with 14 times the total mass of the cough-relieving and phlegm-reducing composition of water for 2 times, 2 hours each time. After filtering the extract, combine and concentrate it, and concentrate it under reduced pressure (temperature 60 - 80°C, vacuum degree 0.04 - 0.08 MPa) to a relative density of 1.10 (measured at 60°C), and filter with 300 meshes to obtain a concentrated solution. Dry the concentrated solution at an inlet air temperature of 170 ± 5°C and an outlet air temperature of 80 ± 5°C to obtain the dried powder of the composition.
[0078] The preparation process of this hard candy for clearing the throat and moistening the larynx is the same as that of Example 11.
[0079] Test Example 1
[0080] This test example conducted a sensory evaluation on the cough-relieving and phlegm-reducing compositions prepared in the above Examples 1 - 9.
[0081] To evaluate the quality of the compositions obtained in the present invention, a 10-member evaluation panel consisting of professionals conducted a sensory evaluation experiment on the samples prepared in Examples 1 to 9. The compositions were subjected to simple pulverization, and a comprehensive score was given based on the appearance, dissolution state, taste of the compositions, as well as the odor and color of the brewed water. The calculation method for the comprehensive score is as follows: Each of the five evaluation indicators has a full score of 100 points, and the weights in the evaluation system are 20% respectively. The score of each indicator is multiplied by the proportion of the weight, and the scores are added up to obtain the comprehensive score. The specific results are shown in Table 2.
[0082] Table 2 Comprehensive evaluation results of the compositions
[0083] Group 1 2 3 4 5 6 7 8 9 10 Average comprehensive score Example 1 94 89 92 94 90 88 92 94 91 89 91.3 Example 2 73 82 71 81 81 83 78 81 73 80 78.3 Example 3 82 81 75 81 72 73 81 80 72 88 78.5 Example 4 80 79 82 73 74 82 71 76 85 71 77.3 Example 5 85 72 81 75 81 72 75 73 80 82 77.6 Example 6 80 85 82 80 76 80 78 81 77 75 79.4 Example 7 84 84 79 80 82 78 79 80 76 74 79.4 Example 8 82 82 76 79 72 69 68 72 70 67 73.7 Example 9 79 77 80 74 68 70 65 69 70 65 71.7
[0084] From the above test results, it can be seen that the compositions prepared using the formulations of the examples all have the appearance, odor, color, dissolution state and flavor that this variety should have. Among them, the sensory evaluation score of the composition obtained in Example 1 is above 90 points, and each index is better than the standard regulations, indicating that its performance is the best and it is suitable for large-scale industrial production and wide promotion. The scores of the compositions prepared in other examples are all below 80 points, indicating that changing the proportion of raw materials will have a greater impact on the appearance, odor, color, tissue state, taste, etc. of this variety, directly affecting the quality of the product.
[0085] Test Example 2
[0086] From the above test examples, it can be seen that the cough-relieving and phlegm-dissipating composition prepared in Example 1 has the best sensory score. Therefore, in this test example, the cough-relieving and phlegm-dissipating composition prepared in Example 1 of the above effect examples was investigated for its use effects in different populations.
[0087] 1. Statistical results of clinical use effects:
[0088] There were 30 subjects in total, aged 24 to 50 years old, with clinical symptoms of cough, swollen and red throat, and expectoration.
[0089] Treatment method: Under the premise of voluntariness, the patients took the cough-relieving and phlegm-dissipating composition prepared in Example 1 of the present invention, 3 g each time, brewed with boiling water, taken orally, once in the morning and once in the evening, and the symptoms of the patients were observed after two weeks.
[0090] Diagnostic criteria:
[0091] Cough cured: No cough and expectoration phenomena, and the swollen and red throat subsides.
[0092] Cough effective: The phenomena of cough, swollen and red throat, and expectoration are alleviated.
[0093] Cough ineffective: The symptoms are not improved.
[0094] Results: Among 30 patients with cough, 27 were cured, 3 were effective, the cure rate was 90%, and the effective rate was 100%. There were no obvious changes in blood routine, urine routine, and stool routine tests after taking, indicating that the present invention has no obvious impact on the health of the subjects. The clinical trial results show that the present invention has an obvious improvement effect on symptoms such as cough, sore throat, and expectoration.
[0095] 2. Typical cases
[0096] Case 1:
[0097] Mr. Wang, male, 43 years old, smokes, has had a cough for many days without improvement, and has a lot of phlegm. The anti-cough and anti-phlegm composition prepared in Example 1 of the present invention was used for treatment, 3 g each time, brewed with boiling water, taken orally, once in the morning and once in the evening. After two weeks, there were no cough and expectoration symptoms, he spoke powerfully, was full of vitality, and there was no recurrence.
[0098] Case 2:
[0099] Ms. Liu, female, 37 years old, has a sore throat, a weak cough, and a sallow complexion. The anti-cough and anti-phlegm composition prepared in Example 1 of the present invention was used for treatment, 3 g each time, brewed with boiling water, taken orally, once in the morning and once in the evening. After two weeks, all aspects of the body function improved, the complexion turned rosy, there were no cough and sore throat phenomena, and she lived and went to work normally.
[0100] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, or improvements made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. A hard candy for clearing the throat and moistening the larynx, characterized in that, it is made of the following components in parts by weight: 4.5 - 6.5 parts of tangerine peel, 4.5 - 6.5 parts of honeysuckle flower, 5 - 6 parts of mint, 3.5 - 4.5 parts of forsythia leaf, 3 - 4 parts of phragmites rhizome, 1.5 - 2.5 parts of platycodon root, 0.8 - 1.3 parts of boat-fruited sterculia seed, 0.8 - 1.3 parts of lily bulb, 0.5 - 1.5 parts of monk fruit and 0.8 - 1.3 parts of bitter almond.
2. The hard candy for clearing the throat and moistening the larynx according to claim 1, characterized in that, it is made of the following components in parts by weight: 5 - 6 parts of tangerine peel, 5 - 6 parts of honeysuckle flower, 5.3 - 5.7 parts of mint, 3.5 - 4 parts of forsythia leaf, 3 - 3.5 parts of phragmites rhizome, 1.8 - 2.2 parts of platycodon root, 1 - 1.2 parts of boat-fruited sterculia seed, 1 - 1.2 parts of lily bulb, 0.8 - 1.2 parts of monk fruit and 1 - 1.2 parts of bitter almond.
3. The hard candy for clearing the throat and moistening the larynx according to claim 2, characterized in that, it is made of the following components in parts by weight: 5.5 parts of tangerine peel, 5.5 parts of honeysuckle flower, 5.5 parts of mint, 4 parts of forsythia leaf, 3.5 parts of phragmites rhizome, 2 parts of platycodon root, 1 part of boat-fruited sterculia seed, 1 part of lily bulb, 1 part of monk fruit and 1 part of bitter almond.
4. A hard candy for clearing the throat and moistening the larynx, characterized in that, the raw materials include the dried powder of the water extract of the components described in any one of claims 1 - 3.
5. The hard candy for clearing the throat and moistening the larynx according to claim 4, characterized in that, the preparation process of the dried powder of the water extract is: weighing each component according to the parts by weight, extracting with 10 - 16 times the total mass of the components with water for 2 - 3 times, each time for 1 - 2 hours, combining and concentrating the obtained extraction liquid, and spray drying to obtain the dried powder of the water extract.
6. The hard candy for clearing the throat and moistening the larynx according to claim 4 or 5, characterized in that, the raw materials of the hard candy for clearing the throat and moistening the larynx further include isomaltulose, sweetener, and food flavor. The mass ratio of the dried powder of the water extract, isomaltulose, sweetener, and food flavor is (0.1 - 1.0):(97 - 99):(0.01 - 0.06):(0.3 - 1.5); the preparation process of the hard candy for clearing the throat and moistening the larynx is: weighing the isomaltulose, adding water equivalent to 25 - 35% of its mass, heating to dissolve all the isomaltulose at 0.4 - 0.5 MPa and 105 - 110 °C, and boiling the sugar to reduce its moisture content to less than 2% by mass at 0.8 - 0.9 MPa and 160 - 165 °C; when the temperature of the sugar solution reaches 130 - 140 °C, adding the dried powder of the water extract, sweetener, and food flavor, mixing evenly, casting and molding, and cooling and drying to obtain the hard candy for clearing the throat and moistening the larynx.