Skin antibacterial liquid

Abstract

The invention relates to the technical field of antibacterial products, in particular to skin antibacterial liquid. The skin antibacterial liquid is prepared from the following raw materials in parts by mass: akebiaquinata, cortex dictamni, tribulus terrestris, radix sophorae flavescentis, slough, chlorhexidine acetate, sodium benzoate and purified water. The skin antibacterial liquid is a Chinese herbal medicine preparation, does not contain hormones, has the effects of clearing away heat and toxic materials, removing dampness and relieving itching, sterilizing and treating tinea and promoting wound healing, is high in permeability, can eliminate deep skin inflammation, can cure various difficult and miscellaneous diseases of skin, and relieves pains of patients with skin diseases. The ointment has an inhibiting effect on staphylococcus aureus, escherichia coli and candida albicans, and is suitable for acute, subacute and chronic eczema, specific dermatitis, contact dermatitis, insect biting and crawling dermatitis, paronychia, hormone drug sequelae, pompholyx, sweat stain, miliaria, sunburn, burn, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manuum, tinea cruris, tinea corporis and the like.

Description

Technical Field

[0001] The present invention relates to the technical field of antibacterial products, and particularly to a skin antibacterial liquid. Background Art

[0002] At present, in today's society, due to various factors, the number of skin disease patients has been increasing rapidly in recent years. Skin diseases have become a common, frequently-occurring, and easily-recurrent stubborn skin disease. Skin disease symptoms are on the surface, being common and frequently-occurring diseases. In severe cases, they can affect the patient's study, work, and life. There are many types of skin diseases with complex causes, and the pathogenesis of many skin diseases is still not very clear so far. The diseases are stubborn and difficult to cure. Pathologically speaking, due to the large variety of skin diseases, it cannot be generalized. Western medicine treatment of skin diseases has a quick effect, but it is easy to relapse and rebound because hormones are added to the drugs. Therefore, many patients' conditions relapse and rebound repeatedly, and each time it gets worse.

[0003] Infections of the skin and mucous membranes are mainly caused by bacteria or fungi, such as Staphylococcus aureus, Escherichia coli, Candida albicans, etc. Therefore, in the clinical treatment of skin or mucous membrane wounds, first of all, it is necessary to have an antibacterial effect on wound infections and at the same time promote wound healing. An antibacterial liquid is an external medicine that can inhibit fungal and bacterial infections and is used to treat skin diseases such as ulcers, inflammation, and injuries. At present, although there are a wide variety of these drugs and preparations, they all have the problems of unsatisfactory curative effects or most of the drugs for treating skin diseases having a single function. There is still no antibacterial external medicine on the market that is convenient to make, has no peculiar smell, low irritation, meets relevant microbial indicators, has a good antibacterial effect, and strong antibacterial stability.

[0004] Therefore, there is an urgent need in clinical practice to develop an antibacterial liquid that is non-toxic, non-irritating, has a strong anti-inflammatory effect, a wide application range, and remarkable curative effects. Traditional Chinese medicine uses traditional Chinese medicine for treatment, especially for stubborn skin diseases of chronic diseases, and has very good curative effects, which have been recognized through clinical verification. Summary of the Invention

[0005] The purpose of the present application is to provide a skin antibacterial liquid. This skin antibacterial liquid is a Chinese herbal medicine preparation, does not contain hormones, has the effects of clearing heat and detoxifying, removing dampness and relieving itching, sterilizing and treating tinea, and promoting wound healing. It has strong permeability, can eliminate deep skin inflammation, and can cure various skin intractable diseases, relieving the pain of the majority of skin disease patients.

[0006] In order to achieve the above purpose, the present application provides the following technical solutions: A skin antibacterial liquid, comprising the following raw materials in parts by mass: 5 - 20 parts of Akebia quinata, 5 - 20 parts of Dictamnus dasycarpus Turcz., 5 - 20 parts of Tribulus terrestris L., 5 - 20 parts of Sophora flavescens Ait., 5 - 20 parts of Cicada slough, 0.01 - 1 part of chlorhexidine acetate, 0.01 - 10 parts of sodium benzoate, 20 - 50 parts of purified water.

[0007] Preferably, the mass percentage of chlorhexidine acetate is 0.14 - 0.17%.

[0008] A preparation method of the skin bacteriostatic liquid as described above includes the following steps: S1. Clean and remove impurities from Akebia quinata, Dictamni Cortex, Fructus Tribuli, Sophora flavescens, and Periostracum Cicadae Cryptotympanaatrata Fab- ricius, and dry them to ensure their cleanliness. Then, weigh Akebia quinata, Dictamni Cortex, Fructus Tribuli, Sophora flavescens, Periostracum Cicadae Cryptotympanaatrata Fab- ricius, chlorhexidine acetate, sodium benzoate, and purified water respectively according to parts by weight; S2. Process Akebia quinata, Dictamni Cortex, Fructus Tribuli, Sophora flavescens, and Periostracum Cicadae Cryptotympanaatrata Fab- ricius into granules respectively. Then, add the above-mentioned granules into a stirrer and stir evenly; S3. Add chlorhexidine acetate, sodium benzoate, and purified water to the granules after stirring, heat to 100 °C, and ferment. Then, cool naturally, centrifuge the fermented mixture with a centrifuge, take the centrifugal supernatant, and press-filter the residue to obtain a liquid; S4. Sterilize the above-mentioned liquid uniformly and conduct random inspections to obtain the bacteriostatic liquid.

[0009] An application of the skin bacteriostatic liquid as described above, where the bacteriostatic liquid is used for acute eczema, subacute eczema, chronic eczema, atopic dermatitis, contact dermatitis, insect bite and crawling dermatitis, paronychia, sequelae of hormone drugs, pompholyx, tinea versicolor, prickly heat, sunburn, burn, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manus, tinea cruris, or tinea corporis.

[0010] Preferably, the bacteriostatic liquid is used for acute eczema, subacute eczema, chronic eczema, atopic dermatitis, contact dermatitis, insect bite and crawling dermatitis, paronychia, sequelae of hormone drugs, pompholyx, tinea versicolor, prickly heat, sunburn, burn, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manus, tinea cruris, or tinea corporis caused by Staphylococcus aureus, Escherichia coli, or Candida albicans. Beneficial effects

[0011] The present invention uses Akebia quinata, Dictamni Cortex, Fructus Tribuli, Sophora flavescens, Periostracum Cicadae Cryptotympanaatrata Fab- ricius, chlorhexidine acetate, sodium benzoate, and purified water. This skin bacteriostatic liquid is a Chinese herbal medicine preparation without hormones, and has the effects of clearing heat and detoxifying, removing dampness and relieving itching, sterilizing and treating tinea, and promoting wound healing. It has strong permeability, can eliminate deep skin inflammation, and can cure various skin intractable diseases, relieving the pain of the majority of skin disease patients.

[0012] The present invention has an inhibitory effect on Staphylococcus aureus, Escherichia coli, and Candida albicans, and is applicable to acute, subacute, and chronic eczema, atopic dermatitis, contact dermatitis, insect bite dermatitis, paronychia, sequelae of hormone drugs, dyshidrosis, pityriasis versicolor, prickly heat, sunburn, burns, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manus, tinea cruris, tinea corporis, etc. Specific Embodiments

[0013] The following will detail the present application in conjunction with embodiments. Each example is provided by way of explanation of the present application rather than limiting the present application. In fact, those skilled in the art will clearly understand that modifications and variations can be made to the present application without departing from the scope or spirit of the present application. For example, features shown or described as part of one embodiment can be used in another embodiment to yield yet another embodiment. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present invention shall fall within the scope protected by the embodiments of the present invention.

[0014] A skin bacteriostatic liquid, comprising the following raw materials in parts by mass: 5 - 20 parts of Akebia quinata, 5 - 20 parts of Dictamnus dasycarpus Turcz., 5 - 20 parts of Tribulus terrestris L., 5 - 20 parts of Sophora flavescens Ait., 5 - 20 parts of Periostracum cicadae, 0.01 - 1 part of chlorhexidine acetate, 0.01 - 10 parts of sodium benzoate, and 20 - 50 parts of purified water.

[0015] Preferably, the mass percentage of the chlorhexidine acetate is 0.14 - 0.17%.

[0016] A preparation method of the skin bacteriostatic liquid as described above, comprising the following steps: S1. Wash, remove impurities, and dry Akebia quinata, Dictamnus dasycarpus Turcz., Tribulus terrestris L., Sophora flavescens Ait., and Periostracum cicadae to ensure their cleanliness, and then weigh Akebia quinata, Dictamnus dasycarpus Turcz., Tribulus terrestris L., Sophora flavescens Ait., Periostracum cicadae, chlorhexidine acetate, sodium benzoate, and purified water respectively according to the parts by weight; S2. Process Akebia quinata, Dictamnus dasycarpus Turcz., Tribulus terrestris L., Sophora flavescens Ait., and Periostracum cicadae into granules respectively, and then add the above granules into a stirrer and stir evenly; S3. Add chlorhexidine acetate, sodium benzoate, and purified water to the stirred granules, heat to 100 °C, ferment, then naturally cool, centrifuge the fermented mixture through a centrifuge, take the centrifuged supernatant, and press - filter the residue to obtain a liquid; S4. Sterilize the above liquid uniformly and conduct random inspections to obtain the bacteriostatic liquid.

[0017] Application of a skin bacteriostatic liquid as described above, wherein the bacteriostatic liquid is used for acute eczema, subacute eczema, chronic eczema, atopic dermatitis, contact dermatitis, insect bite and crawling dermatitis, paronychia, sequelae of hormone drugs, pompholyx, tinea versicolor, prickly heat, sunburn, burns, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manus, tinea cruris or tinea corporis.

[0018] Preferably, the bacteriostatic liquid is used for acute eczema, subacute eczema, chronic eczema, atopic dermatitis, contact dermatitis, insect bite and crawling dermatitis, paronychia, sequelae of hormone drugs, pompholyx, tinea versicolor, prickly heat, sunburn, burns, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manus, tinea cruris or tinea corporis caused by Staphylococcus aureus, Escherichia coli or Candida albicans. Example 1

[0019] A skin bacteriostatic liquid, comprising the following raw materials in parts by mass: 10 parts of Akebia quinata, 20 parts of Dictamnus dasycarpus, 10 parts of Tribulus terrestris, 20 parts of Sophora flavescens, 10 parts of Periostracum cicadae, 0.14 part of chlorhexidine acetate, 5 parts of sodium benzoate, 25 parts of purified water, wherein Akebia quinata, Dictamnus dasycarpus, Tribulus terrestris, Sophora flavescens, Periostracum cicadae, chlorhexidine acetate and sodium benzoate are all of medical grade, and the purities of Akebia quinata, Dictamnus dasycarpus, Tribulus terrestris, Sophora flavescens, Periostracum cicadae and sodium benzoate are all ≥99%, the purity of chlorhexidine acetate is ≥98.5%, and the purity of purified water is ≥99%. Example 2

[0020] A skin bacteriostatic liquid, comprising the following raw materials in parts by mass: 20 parts of Akebia quinata, 15 parts of Dictamnus dasycarpus, 10 parts of Tribulus terrestris, 10 parts of Sophora flavescens, 10 parts of Periostracum cicadae, 0.15 part of chlorhexidine acetate, 3 parts of sodium benzoate, 32 parts of purified water. Example 3

[0021] A skin bacteriostatic liquid, comprising the following raw materials in parts by mass: 20 parts of Akebia quinata, 10 parts of Dictamnus dasycarpus, 15 parts of Tribulus terrestris, 10 parts of Sophora flavescens, 5 parts of Periostracum cicadae, 0.17 part of chlorhexidine acetate, 2 parts of sodium benzoate, 38 parts of purified water. Example 4

[0022] A preparation method of a skin bacteriostatic liquid, comprising the following steps: S1. Wash, remove impurities and dry Akebia quinata, Dictamnus dasycarpus, Tribulus terrestris, Sophora flavescens and Periostracum cicadae to ensure their cleanliness, and then weigh Akebia quinata, Dictamnus dasycarpus, Tribulus terrestris, Sophora flavescens, Periostracum cicadae, chlorhexidine acetate, sodium benzoate and purified water respectively according to the parts by weight in Example 1; S2. Process Akebia quinata, Dictamnus dasycarpus, Tribulus terrestris, Sophora flavescens and Periostracum cicadae into particles with a particle size of 1-10 mm respectively, and then add the above powders into a stirrer and stir evenly; S3. Add chlorhexidine acetate, sodium benzoate and purified water to the above-mentioned stirred powder, heat it to 100 °C, carry out fermentation, then cool it naturally, centrifuge the fermented mixture by a centrifuge, take the centrifuged supernatant, and filter-press the residue to obtain a liquid. S4. Sterilize the above-mentioned liquid uniformly and conduct random inspections to obtain the bacteriostatic liquid.

[0023] Microorganisms inhibited: It has an inhibitory effect on Staphylococcus aureus, Escherichia coli and Candida albicans. Example 5

[0024] A preparation method of a skin bacteriostatic liquid, comprising the following steps: S1. Wash, remove impurities and dry Akebia quinata, Cortex Dictamni, Tribulus terrestris, Sophora flavescens and Cicada slough to ensure their cleanliness, and then weigh Akebia quinata, Cortex Dictamni, Tribulus terrestris, Sophora flavescens and Cicada slough, chlorhexidine acetate, sodium benzoate and purified water respectively according to the weight parts in Example 2. S2. Process Akebia quinata, Cortex Dictamni, Tribulus terrestris, Sophora flavescens and Cicada slough into particles with a particle size of 1-10 mm respectively, and then add the above-mentioned powders into a stirrer and stir evenly. S3. Add chlorhexidine acetate, sodium benzoate and purified water to the above-mentioned stirred powder, heat it to 100 °C, carry out fermentation, then cool it naturally, centrifuge the fermented mixture by a centrifuge, take the centrifuged supernatant, and filter-press the residue to obtain a liquid. S4. Sterilize the above-mentioned liquid uniformly and conduct random inspections to obtain the bacteriostatic liquid.

[0025] Microorganisms inhibited: It has an inhibitory effect on Staphylococcus aureus, Escherichia coli and Candida albicans. Example 6

[0026] A preparation method of a skin bacteriostatic liquid, comprising the following steps: S1. Wash, remove impurities and dry Akebia quinata, Cortex Dictamni, Tribulus terrestris, Sophora flavescens and Cicada slough to ensure their cleanliness, and then weigh Akebia quinata, Cortex Dictamni, Tribulus terrestris, Sophora flavescens and Cicada slough, chlorhexidine acetate, sodium benzoate and purified water respectively according to the weight parts in Example 3. S2. Process Akebia quinata, Cortex Dictamni, Tribulus terrestris, Sophora flavescens and Cicada slough into particles with a particle size of 1-10 mm respectively, and then add the above-mentioned powders into a stirrer and stir evenly. S3. Add chlorhexidine acetate, sodium benzoate and purified water to the above-mentioned stirred powder, heat it to 100 °C, carry out fermentation, then cool it naturally, centrifuge the fermented mixture by a centrifuge, take the centrifuged supernatant, and filter-press the residue to obtain a liquid. S4. Sterilize the above liquid uniformly and conduct spot checks to obtain the bacteriostatic liquid.

[0027] Microorganisms inhibited: It has an inhibitory effect on Staphylococcus aureus, Escherichia coli, and Candida albicans.

[0028] Scope of application of this skin bacteriostatic liquid: Acute, subacute, and chronic eczema.

[0029] Atopic (allergic) dermatitis, contact dermatitis, insect bite dermatitis, paronychia, sequelae of hormone drugs, pompholyx, tinea versicolor, prickly heat, sunburn, burns, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manus, tinea cruris, tinea corporis, etc.

[0030] Method of use and effects: (1) For external use, directly apply or spray this product on the affected area, and then put on clothes after it dries. (2) Wash and dry the affected area with clean water in the morning and evening, and then apply this product.

[0031] (3) For eczema, atopic dermatitis, pompholyx, and sequelae of hormone drugs, apply more than 5 times a day. Depending on the severity of the manifestations and signs of eczema, atopic dermatitis, pompholyx, and sequelae of hormone drugs, those with mild symptoms can improve and recover in about half a month; for those with severe symptoms, some patients may experience increased itching, enlarged area, increased rash, or swelling and oozing of yellow water after using the drug. These are all anti-toxic phenomena, which are the reactions of expressing subcutaneous inflammation (toxins). Continue to apply, and the symptom area will gradually shrink, and the condition will gradually improve until the epidermal symptoms disappear. Generally, it can be cured in 1 - 3 months; for those with sequelae of hormone drugs such as dry, hard, and dark skin caused by long-term use of hormone drugs, cracks will appear on the skin after application, and the treatment time will be longer.

[0032] (4) For contact dermatitis, insect bite dermatitis, paronychia, tinea versicolor, prickly heat, sunburn, burns, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manus, tinea cruris, tinea corporis and other skin diseases, apply 3 to 5 times a day according to the condition, and generally can be cured in 1 to 3 weeks. (5) It is currently the only drug in the world that can cure eczema, atopic (allergic) dermatitis, and sequelae of hormone drugs. The cure rates for the above diseases are all above 90%.

[0033] Precautions: ①. There is no need to avoid certain foods during medication. ②. This product shall not be mixed with other drugs. ③. If it accidentally gets into the eyes, rinse with clean water in time. ④. It can be used by pregnant women and children. ⑤. It is ineffective for eczema caused by allergies to animal proteins such as fish, shrimp, milk, eggs, and meat (such eczema accounts for less than 5% of the total number of eczema cases). ⑥. It is prohibited to take orally and should be placed out of the reach of children. ⑦. If it accidentally gets into the eyes, rinse with clean water in time.

[0034] Storage conditions: Keep sealed, protected from light, and placed in a cool and dry place.

[0035] The present invention uses Akebia quinata, Dictamnus dasycarpus Turcz., Tribulus terrestris, Sophora flavescens, Periostracum cicadae, chlorhexidine acetate, sodium benzoate and purified water. This skin bacteriostatic liquid is a Chinese herbal medicine preparation without hormones, and has the effects of clearing heat and detoxifying, removing dampness and relieving itching, sterilizing and treating tinea, and promoting wound healing. It has strong permeability, can eliminate deep inflammation of the skin, and can cure various intractable skin diseases, relieving the pain of patients with skin diseases. The present invention has an inhibitory effect on Staphylococcus aureus, Escherichia coli, and Candida albicans, and is applicable to acute, subacute, and chronic eczema, atopic dermatitis, contact dermatitis, insect bite and crawl dermatitis, paronychia, sequelae of hormone drugs, pompholyx, tinea versicolor, prickly heat, sunburn, burns, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manus, tinea cruris, tinea corporis, etc.

[0036] In the present invention, the terms "an embodiment", "some embodiments", "example", "specific example", or "some examples", etc. mean that the specific features, structures, materials, or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0037] The above are only the preferred embodiments of the present application and are not used to limit the present application. For those skilled in the art, the present application can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A skin antibacterial liquid, characterized in that: The invention comprises the following raw materials in parts by weight: 5-20 parts of Akebia, 5-20 parts of White Ringworm Peels, 5-20 parts of Tribulus Terrestris, 5-20 parts of Sophora Flavescens, 5-20 parts of Insect Exuviae, 0.01-1 parts of Chlorhexidine Acetate, 0.01-10 parts of Sodium Benzoate, and 20-50 parts of Purified Water.

2. The skin antibacterial liquid according to claim 1, characterized in that The mass percentage of the chlorhexidine acetate is 0.14-0.17%.

3. A method for preparing the skin antibacterial liquid according to claim 1, characterized in that: The following steps are involved: S1, clean and remove impurities from Akebia, white ringworm skin, Tribulus terrestris, Sophora flavescens and insect exuviae, dry them to ensure their cleanliness, and then weigh Akebia, white ringworm skin, Tribulus terrestris, Sophora flavescens, insect exuviae, chlorhexidine acetate, sodium benzoate and purified water respectively according to weight parts; S2, processing Akebia, White Ringworm Cortex, Tribulus Terrestris, Sophora Flavescens and Exuviae into granules respectively, and then adding the granules into a blender respectively, and stirring them thoroughly and evenly; S3, adding chlorhexidine acetate, sodium benzoate and purified water to the above-mentioned stirred particles, heating to 100 ° C, fermenting, then naturally cooling, centrifuging the fermented mixed solution by a centrifuge, taking the centrifugal supernatant, and filter pressing the residue to obtain a liquid; S4. Sterilize the above liquids uniformly and conduct random inspection to obtain antibacterial liquid.

4. A use of the skin antibacterial liquid as claimed in claim 1, characterized in that: The antibacterial liquid is used for acute eczema, subacute eczema, chronic eczema, atopic dermatitis, contact dermatitis, insect bite and crawling dermatitis, paronychia, sequelae of hormone drugs, dyshidrosis, tinea versicolor, prickly heat, sunburn, burn, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manuum, tinea cruris or tinea corporis.

5. The use of the skin antibacterial liquid according to claim 4, characterized in that: The antibacterial liquid is used for acute eczema, subacute eczema, chronic eczema, atopic dermatitis, contact dermatitis, insect bite and crawling dermatitis, paronychia, sequelae of hormone drugs, dyshidrosis, tinea versicolor, prickly heat, sunburn, burns, frostbite, wound infection, scabies, tinea capitis, tinea pedis, tinea manuum, tinea cruris or tinea corporis caused by Staphylococcus aureus, Escherichia coli or Candida albicans.