Application of an amino imidazole compound HY-W051988 and its derivatives in resisting RNA virus
By developing the aminoimidazolium compound HY-W051988 targeting Arl8b, the problem of the lack of Arl8-targeted anti-RNA virus agents in the existing technology has been solved, achieving broad-spectrum inhibition and low toxicity against a variety of RNA viruses.
CN120093737BActive Publication Date: 2026-06-05WUHAN UNIV
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- WUHAN UNIV
- Filing Date
- 2025-03-14
- Publication Date
- 2026-06-05
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Figure CN120093737B_ABST
Abstract
The application discloses application of an amino imidazole compound HY-W051988 and a derivative thereof in resisting RNA viruses, and relates to the technical field of biological medicines. 20 H 17 N3O4, and a molecular weight is 362.368. It is verified through a large amount of experimental research that the HY-W051988 has a better RNA virus resisting effect at a low concentration (400 nM), has a significant inhibiting effect on various RNA viruses, has a better broad spectrum, has a small toxicity, and does not affect the normal growth of host cells.
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