Traditional Chinese medicine composition for treating chronic pharyngitis
By formulating a composition containing a variety of traditional Chinese medicines, various problems existing in the treatment of chronic pharyngitis of the existing traditional Chinese medicine composition are solved, effective treatment and good safety and tolerance are achieved, while reducing costs and simplifying the production process.
Patent Information
- Application Number
- CN202510494135.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-20
- Publication Date
- 2025-06-06
AI Technical Summary
The existing traditional Chinese medicine compositions are used to treat chronic pharyngitis, which have problems such as excessive medicinal smell, difficult material extraction, expensive cost, complex boiling process, insufficient efficacy and poor treatment effect.
By preparing a traditional Chinese medicine composition, including medicines such as Pinellia ternata, Magnolia officinalis, Bupleurum, Tulipa, Poria cocos, Suzai, Esperus, Ophiopogon japonicus, lily, Angelica sinensis, White Peony, Hawthorn, etc., it is prepared into a decoction by decoction and concentration.
This traditional Chinese medicine composition can effectively treat pharyngeal allergic and relieve the symptoms of pharyngeal inflammation. It has good safety and tolerance, and is cheap and quick to take, which is suitable for large-scale industrial production.
Abstract
Description
Technical Field
[0001] The invention relates to the field of medicine, and in particular to a Chinese medicine composition for treating pharyngeal paresthesia and relieving pharyngitis symptoms and a preparation method thereof. Background Art
[0002] Chronic pharyngitis is a diffuse disease of the pharyngeal mucosa, submucosa and lymphoid tissue, which is often caused by environmental pollution, high pressure of life, staying up late and overwork, smoking and drinking, mood swings and other factors. The typical clinical symptoms are foreign body sensation in the throat or dryness, pain, itching, difficulty in swallowing, dry retching and other discomforts. The cause of chronic pharyngitis is complex and is closely related to occupation, climate, and eating habits. The symptoms are stubborn. If not treated in time, the disease may persist and may affect other organs and cause other diseases.
[0003] Western medicine treatment for chronic pharyngitis is mainly symptomatic treatment, with the use of antibiotics, glucocorticoids and other drug therapies, which are prone to produce a series of adverse reactions and drug resistance, with poor long-term effects, affecting the patient's psychology and poor patient compliance.
[0004] Chronic pharyngitis belongs to the category of "throat paralysis" in traditional Chinese medicine. Traditional Chinese medicine has a variety of methods for treating this disease and a long history. Traditional Chinese medicine has a unique advantage in treating chronic pharyngitis, with its multi-pathway and multi-target synergistic effect, strengthening the body and eliminating evil, with long-lasting efficacy and small toxic side effects. However, existing traditional Chinese medicine compositions have more or less disadvantages, such as too many medicinal flavors, difficult to obtain materials, expensive prices, complicated boiling process, unclear efficacy, poor therapeutic effect, etc. Therefore, it is urgent to develop a safe, effective, low-cost, and quick-to-take traditional Chinese medicine composition for treating chronic pharyngitis to improve the quality of life of patients with chronic pharyngitis. Summary of the invention
[0005] The purpose of the present invention is to provide a Chinese medicine composition for treating chronic pharyngitis, which is a Chinese medicine composition for treating chronic pharyngitis of yin deficiency and lung dryness type. The composition can effectively treat pharyngeal paresthesia and relieve pharyngitis symptoms, and has good safety and tolerability.
[0006] The present invention is achieved through the following technical solutions.
[0007] The Chinese medicine composition for treating chronic pharyngitis of the present invention is composed of the following raw materials in proportion by weight: 8-11 parts of Pinellia ternata, 5-7 parts of Magnolia officinalis, 5-8 parts of Bupleurum chinense, 5-7 parts of Curcuma aromatica, 8-12 parts of Poria cocos, 2-4 parts of Perilla frutescens, 8-12 parts of Belamcanda chinensis, 5-7 parts of Citron, 8-12 parts of Ophiopogon japonicus, 7-12 parts of Lilium bulbs, 7-13 parts of Angelica sinensis, 8-12 parts of White Peony Root and 3-6 parts of Crataegus pinnatifida.
[0008] Preferably, the Chinese medicine composition is composed of the following raw materials in proportions by weight: 10 parts of Pinellia ternata, 6 parts of Magnolia officinalis, 6 parts of Bupleurum chinense, 6 parts of Curcuma aromatica, 10 parts of Poria cocos, 3 parts of Perilla frutescens, 10 parts of Belamcanda chinensis, 6 parts of Citron, 10 parts of Ophiopogon japonicus, 10 parts of Lilium bulbs, 10 parts of Angelica sinensis, 10 parts of White Peony Root, and 5 parts of Crataegus pinnatifida.
[0009] The method for preparing a traditional Chinese medicine composition for treating chronic pharyngitis of the present invention comprises the following steps.
[0010] S1: According to the weight ratio of the above raw materials, weigh nine herbs including Pinellia ternata, Bupleurum chinense, Curcuma aromatica, Poria cocos, Belamcanda chinensis, Citron, Ophiopogon japonicus, Lilium bulbus, White Peony Root, and Crataegus pinnatifida, add water and boil twice, the first time for 1 hour and the second time for 40 minutes.
[0011] S2: After the second boiling, cool it down a little and add Chinese angelica, Magnolia officinalis, Perilla leaf and Bupleurum to soak.
[0012] S3: Filter, combine the filtrate, concentrate the filtrate to an appropriate amount, add 200 parts of sucrose, 2 parts of benzoic acid and 3 parts of 10% ethylparaben, filter, let stand for 24 hours, filter, add water to 1000 parts, stir well, and fill to obtain the Chinese medicine composition.
[0013] The invention has the advantages that: the Pinellia tuber has the functions of resolving phlegm and drying dampness, descending adverse qi and stopping vomiting; the Bupleurum root has the functions of dispersing wind-heat, soothing the liver and relieving depression, and lifting Yang Qi; the Curcuma root has the functions of promoting Qi and relieving depression, clearing the heart and cooling blood, and promoting bile and relieving jaundice; the Poria has the functions of promoting diuresis and removing dampness, strengthening the spleen, and calming the heart; the Belamcanda can clear away heat and detoxify, and relieve inflammation and relieve sore throat; the Citron can soothe the liver and regulate Qi, soothe the stomach and relieve pain, and remove dampness and resolve phlegm; the Lilium and Ophiopogon japonicus have the functions of nourishing yin and promoting body fluid, moistening the lung and clearing the heart; the White Peony root can restrain yin and stop sweating, and suppress liver yang; the Crataegus can digest food and strengthen the stomach, promote Qi and disperse blood stasis, and remove turbidity and reduce fat; the Angelica sinensis can nourish blood and activate blood circulation, and moisten the intestine and relieve constipation. Magnolia officinalis: removes dampness and eliminates phlegm, and relieves Qi and eliminates fullness; the Perilla leaf has the functions of relieving exterior symptoms and dispersing cold, promoting Qi and harmonizing the stomach. The composition of the present invention is derived from natural plants, is safe and reliable, and has wide applicability; the components cooperate with each other, synergistically enhance the effect, have no obvious toxic and side effects, have mild and lasting medicinal properties, and are suitable for long-term treatment of chronic diseases; the formula drugs are all conventional Chinese medicines, which are abundant in resources, easy to obtain, low in price, easy to popularize, and simple in preparation method, and are suitable for large-scale industrial production. DETAILED DESCRIPTION
[0014] The technical solutions in the embodiments of the present invention will be described clearly and completely below. The described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments.
[0015] The Chinese medicine composition for treating chronic pharyngitis used in this embodiment is made of the following raw materials in proportion by weight: 10 parts of Pinellia ternata, 6 parts of Magnolia officinalis, 6 parts of Bupleurum chinense, 6 parts of Curcuma aromatica, 10 parts of Poria cocos, 3 parts of Perilla frutescens, 10 parts of Belamcanda chinensis, 6 parts of Citron, 10 parts of Ophiopogon japonicus, 10 parts of Lilium bulbs, 10 parts of Angelica sinensis, 10 parts of White Peony Root, and 5 parts of Crataegus pinnatifida.
[0016] In this embodiment, according to the above-mentioned preparation method: weigh the raw materials according to the amount, add water to boil, take the filtrate and concentrate it under reduced pressure, and add auxiliary materials to prepare a decoction. Example 1
[0017] Zhang, male, 45 years old, first visit on July 15, 2015. The patient had pharyngeal discomfort after catching a cold 3 months ago. After self-medication, the cold symptoms were relieved, but the foreign body sensation in the throat, dry throat, and itchy throat persisted. The symptoms worsened in the morning, with irritating coughs from time to time, a small amount of white sputum, no fever, sore throat, and normal swallowing. The patient's pharyngeal mucosa was dark red, and the lymph follicles on the posterior pharyngeal wall were hyperplastic; the breath was stable and there was no odor; the mouth was dry and did not want to drink more, and the diet and bowel movements were normal. According to Chinese medicine, it belongs to yin deficiency and lung dryness, and the throat is not nourished. The treatment is mainly to nourish yin and moisten the lungs, and relieve the throat and open the voice. The pharyngitis mixture was given, 10ml each time, 3 times a day, and the symptoms disappeared after 2 months. Example 2
[0018] Jiang, female, 38 years old. The patient suffered from acute upper respiratory tract infection 4 months ago, which left pharyngeal discomfort. She always felt that there was a foreign body in the throat, could not cough or swallow, and often had tingling in the throat, especially when swallowing saliva or eating irritating food, the pain was aggravated, and the symptoms would be aggravated if she spoke more. Self-medication with drugs such as Kaihoujian and Qingyan Lihou Keli can only provide temporary relief. The patient's pharyngeal mucosa was congested, the lymph follicles on the posterior pharyngeal wall were hyperplastic and swollen, the tip of the tongue was red, and the tongue coating was thin and yellow; the breathing was stable, without odor, and the voice of speech was normal; the mouth was dry, liked cold drinks, and had an irritable temperament. The Chinese medicine dialectical syndrome belongs to liver depression and fire, which disturbs the throat. The pharyngitis mixture was given, 10ml each time, 3 times a day. After one month, the foreign body sensation in the throat was not obvious, the pain basically disappeared, and the congestion of the pharyngeal mucosa was significantly reduced. He was advised to eat a light diet and regulate his mood. No recurrence was found in the 2-month follow-up. Example 3
[0019] Sun, male, 50 years old, first diagnosed on July 19, 2015. One year ago, the patient had a feeling of pharyngeal obstruction without obvious cause, as if there was phlegm sticking, sputum was uncomfortable, and he often needed to clear his throat. It was aggravated after fatigue, accompanied by fatigue, shortness of breath, laziness, poor appetite, abdominal distension, and loose stools. The patient's pharyngeal mucosa was pale, the lymph follicles on the posterior pharyngeal wall were hyperplastic, and the tongue coating was white and greasy; the voice was low and the breathing was steady; the stomach was bloated, liked warmth and pressure, and had frequent urination at night. According to Chinese medicine, it belongs to spleen deficiency, endogenous phlegm and dampness, which blocked the throat. The treatment is to strengthen the spleen and replenish qi, resolve phlegm and relieve throat. The patient was given pharyngitis mixture, 10 ml each time, 3 times a day. The symptoms disappeared after 2 months, and the condition was stable after 3 months of follow-up. Example 5
[0020] Zhao, female, 28 years old, first visit on March 20, 2016. The patient is a teacher who usually uses her voice frequently. Two months ago, she developed hoarseness and dry and painful throat due to long-term excessive use of her voice, which was slightly relieved after drinking water, accompanied by fever in the five hearts, hot flashes in the afternoon, night sweats, and soreness of the waist and knees. The patient's pharyngeal mucosa is dry and less saliva, the vocal cords are congested and thickened; the voice is hoarse and the breath is slightly short; Chinese medicine dialectical syndrome belongs to kidney yin deficiency and throat dryness. She was given pharyngitis mixture, 12 ml each time, 3 times a day. On April 20, 2016, she was re-examined. The congestion and hypertrophy of the vocal cords were significantly reduced, and the voice basically returned to normal. She was advised to pay attention to the hygiene of the voice and avoid excessive fatigue. No recurrence was found in the 2-month follow-up. Example 5
[0021] Liang, male, 40 years old, had a foreign body sensation in the throat 6 months ago due to work pressure. He frequently cleared his throat and felt that there was phlegm in the throat, but he could not cough it out or swallow it. The symptoms worsened when his mood fluctuated, accompanied by chest tightness, flank pain, belching, and sighing. The patient had no obvious congestion in the throat, mild hyperplasia of the lymph follicles on the posterior pharyngeal wall, dark complexion, and frequent sighing; the TCM syndrome was liver depression and qi stagnation, phlegm and qi intertwined, and reflux to the throat. He was given pharyngitis mixture, 10 ml each time, 3 times a day, and the symptoms disappeared after 1 month. The condition did not recur after 4 months of follow-up. Example 6
[0022] Zhou, female, 75 years old. One and a half months ago, the patient developed dry itchy throat and foreign body sensation after catching a cold, followed by coughing, no sputum or little sputum, irritating dry cough, aggravated cough at night, affecting sleep, aggravated cough after cold air and odor stimulation, and poor effect of taking cough medicine. The patient's pharyngeal mucosa is slightly pale, and a small amount of mucus can be seen attached to the posterior pharyngeal wall; the cough is crisp, without sputum sound; nasal itching, sneezing, clear runny nose, fear of wind and cold, spontaneous sweating. Chinese medicine dialectical belongs to wind evil invading the lungs, and the lungs fail to vent. Give pharyngitis mixture, 10ml each time, 3 times a day, two weeks later, the second visit, all symptoms have been relieved, advise to keep warm, prevent colds, exercise appropriately to strengthen physical fitness, follow-up for 3 months without recurrence. Example 7
[0023] Mr. Wu, male, 60 years old. The patient had a sore throat after catching a cold 3 weeks ago. The pain worsened when swallowing, accompanied by fever, with the highest body temperature of 38.5℃. After anti-infection treatment by Western medicine, the fever subsided, but the sore throat and difficulty swallowing persisted, and the mouth and throat were dry, the stool was dry and hard, and the urine was short and red. The patient's pharyngeal mucosa was congested and ulcerated, with purulent secretions, red tip of the tongue, yellow fur; slightly coarse breathing; headache, bad breath, and irritability. Chinese medicine dialectics belong to excessive heat in the lungs and stomach, and heat toxicity. The patient was given a pharyngitis mixture, 15ml each time, 3 times a day. The symptoms disappeared after 1 month, and no abnormalities were found in the 2-month follow-up. Example 8
[0024] Zheng, female, 25 years old. Two months ago, the patient had a foreign body sensation in the throat for unknown reasons. She felt nauseous when brushing her teeth in the morning, had dry heaves from time to time, and coughed up phlegm in the throat, which was white and sticky. Her diet was OK, her bowel movements were normal, and her menstrual cycle and quantity were normal. The patient's pharyngeal mucosa was slightly congested, the lymph follicles on the posterior pharyngeal wall were hyperplastic, and her tongue coating was white and slippery; there was a small amount of phlegm sound in the throat; there was sometimes fullness in the epigastric area, she liked to press it, and her mouth was bland and not thirsty; Chinese medicine dialectical analysis showed that the patient had phlegm and dampness blocking the middle part of the body, and the upper part invaded the throat. She was given a pharyngitis mixture, 10 ml each time, 3 times a day. After half a month, the second visit showed that all symptoms had basically disappeared. She was advised to eat regularly and avoid raw, cold and greasy food. The condition was stable after 3 months of follow-up. Example 9
[0025] Chen, male, 48 years old. One month ago, the patient developed tingling and burning pain in the throat after drinking, which worsened when swallowing, accompanied by bad breath, swollen and painful gums, constipation, yellow and red urine, and a preference for cold drinks. The patient's pharyngeal mucosa was red and swollen, the lymph follicles on the posterior pharyngeal wall were congested, the gums were red and swollen, the tongue coating was thick and greasy, and the breath was suffocating. According to Chinese medicine, it belongs to the blazing stomach fire, which burns the throat. He was given pharyngitis mixture, 10 ml each time, 3 times a day. After one month, the pharyngeal symptoms basically disappeared, and his diet was normal. He was advised to quit drinking and eat a light diet. There was no recurrence during the six-month follow-up.
[0026] The Chinese medicine compound for treating chronic pharyngitis of the present application eliminates fullness and distension, regulates qi and resolves phlegm with Radix Pinelliae, Cortex Magnoliae, and Folium Perillae, relieves liver qi and resolves depression with Radix Bupleuri, Radix Curcumae, and Fructus Citri Reticulatae, and promotes smooth qi movement with Radix Ophiopogonis, Bulbus Lilii, Radix Angelicae Sinensis, and Radix Paeoniae Alba, nourishes blood and nourishes yin, moistens the lungs and calms the mind, relieves sore throat and relieves voice, clears fire and detoxifies, and resolves phlegm and eliminates dampness. In addition, Poria is added to invigorate the spleen and infiltrate dampness, Belamcanda is added to clear away heat and relieve sore throat, and Crataegus is added to digest food and resolve accumulation, and promotes smooth qi movement, and the whole side plays together, promotes qi and resolves depression, descends adverse reactions and resolves phlegm, and moistens the lungs and relieves sore throat. The effect of this prescription for treating chronic pharyngitis is clear and has no obvious toxic and side effects, and the drug components are in sufficient supply, and the finished product is a decoction, which is easy to adhere to, and has a good therapeutic effect for chronic pharyngitis.
Claims
1. A Chinese medicine composition for treating chronic pharyngitis, characterized by The following raw materials are composed by weight: 8-11 parts of Pinellia ternata, 5-7 parts of Magnolia officinalis, 5-8 parts of Bupleurum chinense, 5-7 parts of Curcuma aromatica, 8-12 parts of Poria cocos, 2-4 parts of Perilla frutescens, 8-12 parts of Belamcanda chinensis, 5-7 parts of Citron, 8-12 parts of Ophiopogon japonicus, 7-12 parts of Lilium bulgur, 7-13 parts of Angelica sinensis, 8-12 parts of White Peony Root, and 3-6 parts of Crataegus pinnatifida.
2. A Chinese medicine composition for treating chronic pharyngitis according to claim 1, characterized in that The composition is composed of the following raw materials in proportion by weight: 10 parts of Pinellia ternata, 6 parts of Magnolia officinalis, 6 parts of Bupleurum chinense, 6 parts of Curcuma aromatica, 10 parts of Poria cocos, 3 parts of Perilla frutescens, 10 parts of Belamcanda chinensis, 6 parts of Citron, 10 parts of Ophiopogon japonicus, 10 parts of Lilium bulbs, 10 parts of Angelica sinensis, 10 parts of White Peony Root, and 5 parts of Crataegus pinnatifida.
3. A method for preparing a Chinese medicine composition for treating chronic pharyngitis according to claim 1 or 2, characterized in that The following steps are involved: S1: According to the weight ratio of the above raw materials, nine herbs including Pinellia ternata, Bupleurum chinense, Curcuma aromatica, Poria cocos, Belamcanda chinensis, Citron, Ophiopogon japonicus, Lilium bulbuscularis, White Peony Root and Crataegus pinnatifida were weighed and decocted twice, the first time for 1 hour and the second time for 40 minutes; S2: After the second boiling, add Chinese angelica, Magnolia officinalis, Perilla leaf and Bupleurum chinense to soak; S3: Filter, combine the filtrate, concentrate the filtrate to an appropriate amount, add 200 parts of sucrose, 2 parts of benzoic acid and 3 parts of 10% ethylparaben, filter, let stand for 24 hours, filter, add water to 1000 parts, stir well, and fill to obtain the Chinese medicine composition.