A diaper cream and a method for preparing the same

Abstract

The present application belongs to the field of cosmetics, and discloses a buttock-protecting cream, which comprises the following components in percentage by weight: petrolatum: 44-57.5%; light polar synthetic oil: 35-45%; lanolin: 3-8%; trihydroxy stearyl alcohol: 2-5%; microcrystalline wax: 1-5%; oil-absorbing powder: 1-3%; white beeswax: 0.5-2%. The buttock-protecting cream of the present application takes petrolatum as the main component, and light polar synthetic oil, lanolin, trihydroxy stearyl alcohol, microcrystalline wax and white beeswax as auxiliary components, and the six components are combined to significantly improve the forming capacity of the isolation layer and the hardness support during temperature change, and achieve better urine isolation effect. Meanwhile, the present application also provides a preparation method of the buttock-protecting cream.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of cosmetics, in particular to a buttock protection cream and a preparation method thereof. BACKGROUND

[0002] Baby red buttocks, also known as diaper rash or diaper dermatitis in medicine, is mainly caused by red buttocks due to skin damage on the buttocks, or secondary infection of bacteria, fungi and other microorganisms on the damaged skin.

[0003] The main function of the buttock protection cream is to inhibit baby red buttocks. By applying the buttock protection cream to the baby's buttocks, a protective film is formed to play an isolation role. Therefore, the isolation performance is the primary performance considered for the buttock protection cream.

[0004] The following documents related to the buttock protection cream can be referred to:

[0005] Patent application with publication number CN112263527A, subjecting to a baby buttock protection cream and a preparation method thereof;

[0006] Patent application with publication number CN112315860A, subjecting to a Chinese herbal medicine system baby buttock protection cream and a preparation method thereof;

[0007] Patent application with publication number CN110638727A, subjecting to a baby buttock protection composition, a preparation method and application thereof;

[0008] Patent application with publication number CN110302121A, subjecting to a baby buttock protection cream containing plant essence and a preparation method thereof, which discloses the following formula: petrolatum 60-90 parts, liquid paraffin 5-15 parts, microcrystalline wax 2-10 parts, camellia seed oil 2-10 parts, zinc oxide 3-8 parts, antioxidant 0.1-1 part, bisabolol 0.1-1 part, evening primrose oil 1-5 parts, olive fruit extract 0.01-1 part, and water 0.01-1 part.

[0009] Patent application with publication number CN103027871A, subjecting to a baby buttock protection cream, which discloses the following formula: 55-78% petrolatum, 3-7% aloe extract essence, 10-15% sterilized deionized water, 2-4% microcrystalline wax, 3-7% sponge gourd extract essence, 1-3% polyglyceryl-3 stearic acid, 1-3% vitamin E, 1-3% hydroxypropyl benzene ester, and 1-3% hydroxybenzyl.

[0010] Among them, CN110302121A and CN103027871A are formulas with petrolatum as the main component. In the above-mentioned solutions, in addition to petrolatum as the main component, other oils such as liquid paraffin, microcrystalline wax, and polyglyceryl-3 stearic acid are also used.

[0011] In the research, it is found that the isolation layer for building stable and effective hardness support in temperature change cannot be fully realized by only using petrolatum.

[0012] Therefore, the core problem and demand of the present case is how to optimize the existing hip balm and improve the forming ability and hardness support of the isolation layer built by the hip balm in temperature change to achieve better urine isolation effect. SUMMARY

[0013] The purpose of the present application is to provide a hip balm, which uses petrolatum as the main component, light polar synthetic oil, lanolin, trihydroxy stearyl, microcrystalline wax and white beeswax as auxiliary components, and the six components are combined to significantly improve the forming ability and hardness support of the isolation layer in temperature change, and achieve better urine isolation effect.

[0014] Meanwhile, the present application also provides a preparation method of the hip balm.

[0015] To achieve the above purpose, the present application provides the following technical solutions:

[0016] A hip balm, comprising the following components by weight percentage:

[0017] Petrolatum: 44-57.5%;

[0018] Light polar synthetic oil: 35-45%;

[0019] Lanolin: 3-8%;

[0020] Trihydroxy stearyl: 2-5%;

[0021] Microcrystalline wax: 1-5%;

[0022] Oil-absorbing powder: 1-3%;

[0023] White beeswax: 0.5-2%.

[0024] The functions and cooperation mechanisms of the above components are as follows:

[0025] Petrolatum: Petrolatum is a common skin care ingredient, which has the functions of moisturizing, nourishing and protecting skin barrier, and can form a protective film on the skin surface to isolate and reduce the damage of external irritants to the skin,

[0026] Lightweight polar synthetic oils: Take ethylhexyl stearate and caprylic / capric triglyceride as an example, both of which are excellent emollients and humectants. On the one hand, they can bring a smooth and delicate skin feel, making the butt cream easier to spread, and not leaving an oily or sticky feeling on the skin. On the other hand, ethylhexyl stearate has good penetration, which can help the active ingredients in the butt cream penetrate deeper into the skin, thereby achieving better results. In addition, ethylhexyl stearate can also act as a solvent and carrier, helping other ingredients in the butt cream to disperse and dissolve uniformly, improving stability and uniformity, and enhancing the barrier effect.

[0027] Lanolin: The oil compounds contained in lanolin can adhere to the surface of the skin, forming a protective film that reduces the damage of external irritants to the skin. At the same time, the fatty acids and phospholipids contained in lanolin can accelerate cell regeneration and repair, improving healing speed.

[0028] Trihydroxystearin: It is a thickening agent, suspending agent and dispersing agent formed by hydrogenation and oxidation of castor oil. It has a long-chain glyceride structure and forms a three-dimensional network structure through non-covalent bonds between molecules, stabilizing the formula. Trihydroxystearin has good compatibility with mineral oil and lightweight polar synthetic oils, the two main ingredients, and can form a crystalline molecular network structure that is less affected by oil. Under high temperature shear, trihydroxystearin molecules stretch and expand to an inflated state, with a large swelling volume, which can suspend mineral oil, lightweight polar synthetic oils and other ingredients, making the cream stable and not layered at high temperatures, maintaining the texture and hardness of the cream.

[0029] Microcrystalline wax: Microcrystalline wax is a refined synthetic wax with properties similar to microcrystalline wax. It has good gloss, high melting point and light color. It can also be used as a wax base for products, providing good texture and stability. Microcrystalline wax has good oil absorption properties and can form a stable and uniform cream with various solvents and waxes, with good adhesion and spreadability. It is not brittle at low temperatures and can prevent oil from separating when added to liquid oil, maintaining the hardness of the cream.

[0030] Oil-absorbing powder: Take aluminum starch octenylsuccinate as an example. Adding an appropriate amount of aluminum starch octenylsuccinate to the butt cream can significantly reduce the greasy feeling caused by oil components, giving the skin a soft and smooth feel, and improving the skin feel of the product. At the same time, the porous structure can improve air permeability, allowing the butt cream to isolate and not cause redness when used.

[0031] White beeswax: White beeswax can build a moisturizing barrier on the skin surface, deeply nourish to achieve the effect of water, and provide soothing and repair for damaged skin, anti-inflammatory to reduce sensitive symptoms, and help treat red buttocks. Temperature changes have little effect on natural beeswax, and it will not deteriorate at high temperatures, effectively protecting active ingredients in cosmetics. White beeswax can be used as a base for ointments, providing good emulsification and thickening effects, improving the texture, viscosity and permeability of the buttock cream, helping ingredients to disperse evenly, making the product easy to apply and absorb.

[0032] From the aspects of urine isolation and high and low temperature performance, the synergistic mechanism between the above components is as follows: lanolin raw material itself has certain viscosity, which is speculated to fix liquid droplets immediately when it comes into contact with urine, slowing down the diffusion speed of liquid droplets, but lanolin itself has good water absorption, which will absorb urine over time, affecting the urine isolation effect. The increase of the addition amount will also increase the water absorption, which will affect the long-term urine isolation effect of the buttock cream. The use of the inherent characteristics of lanolin can help improve the urine isolation performance; trihydroxy stearyl alcohol and mineral oil and ethylhexyl stearate can form a crystalline molecular network structure, which helps to stabilize the compatibility of each component and ensure the uniformity of the film of the buttock cream. Under high temperature shear, the molecules stretch and expand to an inflated state, which can well suspend light synthetic oils and lanolin with low melting point, ensuring the durability of the film. Based on the high humidity and stuffy environment of infants using diapers for a long time, it is necessary to add trihydroxy stearyl alcohol to improve the urine isolation performance under high temperature conditions. In addition, microcrystalline wax and white beeswax can form a stable and uniform cream with light polar synthetic oils, mineral oil and other active ingredients, which has good adhesion and extensibility, and can help to improve the uniformity and durability of the film of the buttock cream, and synergistically enhance the urine isolation performance.

[0033] According to the verification of different cases of the present application, each formula has significant advantages in at least one of the urine isolation performance, high temperature performance and low temperature performance compared with the comparative cases.

[0034] In the above-mentioned buttock cream, the following components are included in the following weight percentage:

[0035] Mineral oil: 44.7-54%;

[0036] Light polar synthetic oil: 35-45%;

[0037] Lanolin: 3-8%;

[0038] Trihydroxy stearyl alcohol: 2-3%;

[0039] Microcrystalline wax: 1-1.5%;

[0040] Oil-absorbing powder: 1-1.5%;

[0041] White beeswax: 0.5-1%.

[0042] The urine isolation performance and high temperature performance of the preferred formula are significantly superior to those of the comparative examples.

[0043] The diaper cream also contains 0.1-1% macadamia nut oil.

[0044] Note: Unless otherwise specified, the percentages in the present application are all weight percentages.

[0045] Macadamia nut oil: also known as Hawaiian nut oil, the seed is dark yellow, and the oil content of the dry kernel is 75-79%. Macadamia nut oil is the only natural plant oil containing a large amount of palmitoleic acid. Its fatty acid composition is similar to human sebum, and it has high stability, does not need to add antioxidants, has a high dispersion coefficient and skin permeability. Adding macadamia nut oil to the diaper cream can increase lubricity and nourishment, improve extensibility, make the film more uniform, and improve the isolation effect. At the same time, macadamia nut oil has healing and soothing effects, which can accelerate the repair of red buttocks.

[0046] In the diaper cream described above, the light polar synthetic oil is ethylhexyl stearate and / or caprylic / capric triglyceride.

[0047] In the diaper cream described above, the oil-absorbing powder is aluminum starch octenylsuccinate and / or boron nitride.

[0048] In the diaper cream described above, it also contains a redness-reducing soothing ingredient; the redness-reducing soothing ingredient is one or more of stearyl glycyrrhetinate, bisabolol, and Centella asiatica leaf extract.

[0049] Of course, other plant extracts or other functional ingredients with similar functions can also be added to the formula of the present application in the field to achieve the soothing and redness-reducing effect on the tender skin of babies.

[0050] In the diaper cream described above, the amount of the redness-reducing soothing ingredient is 0.1-1.5%.

[0051] In the diaper cream described above, it also contains an active ingredient for inhibiting urease activity; the active ingredient is pomegranate peel extract and / or quercetin; the amount of the active ingredient is 0.001-0.01%.

[0052] As another core innovation point of the present application, the present application uses pomegranate peel extract in the formula. It has been reported in existing literature that pomegranate peel extract can inhibit urease activity;

[0053] Urease is an enzyme that catalyzes the hydrolysis of urea into ammonia and carbon dioxide, has high specificity, and widely exists in microorganisms and animal and plant tissues, is the earliest enzyme to be crystallized and proved to be a protein. When urea is hydrolyzed, the generated ammonia is the main component causing the redness and irritation of the baby's skin, and inhibiting the activity of urease is another main core means to improve the diaper rash under the premise of realizing the isolation effect.

[0054] Meanwhile, the application also discloses a preparation method of the buttock cream as described in any one of the above, comprising the following steps:

[0055] Step 1: mixing petrolatum, light polar synthetic oil, lanolin, trihydroxystearin, microcrystalline wax and white beeswax, heating to melting and homogenizing;

[0056] Step 2: homogenizing under stirring after cooling to 55-70 DEG C;

[0057] Step 3: adding oil-absorbing powder to step 2, homogenizing under stirring, and then cooling and discharging.

[0058] More specifically, the method of the application is as follows: Step 1: stirring and heating ethylhexyl stearate, lanolin, trihydroxystearin, microcrystalline wax, white beeswax, macadamia nut oil and stearyl glycyrrhetinate in the redness-removing soothing ingredient to 85-95 DEG C, keeping for 5-20 minutes until completely dissolved, and homogenizing to obtain component A;

[0059] Step 2: homogenizing under stirring after cooling component A to 55-70 DEG C;

[0060] Step 3: separately mixing other components in the redness-removing soothing ingredient such as centella asiatica leaf extract, and active components for inhibiting urease activity such as pomegranate peel extract, and homogenizing until completely dissolved to obtain component B;

[0061] Step 4: homogenizing under stirring after cooling to 38-48 DEG C, adding component B and component C (oil-absorbing powder such as aluminum starch octenylsuccinate, and other components in the redness-removing soothing ingredient such as bisabolol), and then obtaining the buttock cream after cooling to 30-38 DEG C under stirring.

[0062] Compared with the prior art, the application has the following beneficial effects:

[0063] The buttock cream of the application takes petrolatum as the main component, light polar synthetic oil, lanolin, trihydroxystearin, microcrystalline wax and white beeswax as auxiliary components, and the six components are combined, so that the forming capacity of the isolation layer and the hardness support during temperature change are significantly improved, and better urine isolation effect is realized.

[0064] In the preferred scheme of the present application, pomegranate peel extract is used, and we have found that pomegranate peel extract can inhibit urease activity. The present application is another main core means for improving diaper rash by inhibiting the activity of urease, which is the premise for achieving the isolation effect. BRIEF DESCRIPTION OF DRAWINGS

[0065] Figure 1 The contact angle photo of the blank test group in the contact angle test;

[0066] Figure 2 The contact angle photo of Example 2 in the contact angle test. DETAILED DESCRIPTION

[0067] The technical solutions of the present application will be described in detail below with reference to the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0068] Source description of raw materials

[0069] The raw materials used in the present application can refer to Table 1 below;

[0070] Table 1 Raw material source table

[0071]

[0072]

[0073] The first part of the examples and comparative examples refer to the formulations in Table 2, and the formulations are prepared according to the following steps:

[0074] Example 1:

[0075] Step 1: Stir the petrolatum, ethylhexyl stearate, lanolin, trihydroxystearin, microcrystalline wax, white beeswax, and macadamia oil to 85-95℃, and keep the temperature for 5-20 minutes until completely dissolved, and then homogenize to obtain component A;

[0076] Step 2: Stir component A to 55-70℃, and homogenize uniformly;

[0077] Step 3: Mix the pomegranate peel extract and water separately until completely dissolved to obtain component B;

[0078] Step 4: Stir to 38-48℃, add component B and component C (aluminum starch octenylsuccinate and bisabolol), and homogenize uniformly under stirring, and then stir to 30-38℃ to obtain the said nappy cream.

[0079] Table 2 Formulation of buttock cream unit: g

[0080]

[0081]

[0082] The proportion of the redness relieving component in each of the above examples and comparative examples can refer to Table 3 as follows:

[0083] Table 3 Formulation of redness relieving component unit: g

[0084] Bisabolol Bisabolol Centella asiatica leaf extract Example 1 0 0.1 0 Example 2 0.195 0.2 0.1 Example 3 0.5 0 0.5 Example 4 0.33 0.33 0.33 Example 5 0 0.3 0.29 Example 8 0.2 0 0

[0085] Performance test

[0086] The above samples are subjected to the following tests: instant urine isolation effect-contact angle test, overall sensory average score, long-acting 4-hour urine isolation effect, high and low temperature performance, and redness relieving test.

[0087] The specific test method is as follows:

[0088] Test item 1: instant urine isolation effect-contact angle test

[0089] Test method:

[0090] The sample is evenly applied on the pigskin with a sample applicator, and the pigskin is evenly coated with the sample with a latex finger glove finger in an amount of 25 mg / cm 2 . The pigskin after coating is placed in an environment with a temperature of 25.6°C and a relative humidity of 66% for 5 minutes. The artificial urine is quantitatively dropped on the pigskin, and the automatic contact angle measuring instrument is used for testing. Each sample is subjected to three parallel tests, and then the average value is taken.

[0091] Result explanation

[0092] If the contact angle is < 90°, the sample to be tested has hydrophilicity; if the contact angle is ≥ 90°, the sample to be tested has hydrophobicity.

[0093] The test results are shown in Table 4, wherein the test photos of the blank experiment group (pigskin) can be seen in Figure 1 , and the test photos of Example 2 can be seen in Figure 2 .

[0094] Table 4 Contact angle test results

[0095] Sample First time Second time Third time Mean value Blank test group (pigskin) 68.40° 67.90° 70.21° 68.84° Example 1 94.78° 94.21° 95.26° 94.75° Example 2 102.67° 101.13° 103.53° 102.44° Example 3 95.21° 96.03° 95.35° 95.53° Example 4 93.45° 93.56° 94.57° 93.86° Example 5 110.32° 113.35° 112.34° 112.00° Example 6 103.67° 101.23° 103.53° 102.81° Example 7 103.13° 101.57° 103.23° 102.64° Example 8 102.22° 102.39° 102.43° 102.35° Comparative Example 1 92.18° 93.34° 92.09° 92.54° Comparative Example 2 94.67° 95.03° 94.34° 94.68° Comparative Example 3 95.02° 95.33° 94.89° 95.08° Comparative Example 4 94.93° 95.31° 95.05° 95.10° Comparative Example 5 93.67° 93.54° 93.55° 93.59°

[0096] Test item 2: long-acting 4-hour urine isolation effect

[0097] Test method:

[0098] Apply the diaper rash product (0.4g, just enough to cover the filter paper) on the surface of 1 / 4 filter paper, then put a layer of filter paper under it, drop 0.4g of artificial urine on the upper layer of filter paper, stand for 0h and observe whether the filter paper can form a protective film to isolate the artificial urine after 4 hours, whether the filter paper coated with diaper rash cream is wetted.

[0099] The results show

[0100] If the filter paper is not wet and the water droplets are obviously granular, it proves that the diaper rash product has excellent urine isolation effect; if the filter paper is partially wet with a small amount of water droplets, it proves that the diaper rash product has general urine isolation effect; if the filter paper is wet without water droplets, it proves that the diaper rash product has poor urine isolation effect; the evaluation results are divided into three levels: excellent, general and poor.

[0101] The original data results of the urine isolation effect of diaper rash cream are shown in Table 5.

[0102] Table 5 Test results of long-acting 4-hour urine isolation effect

[0103] Sample Smear 0h Smear 4h Evaluation result Example 1 Filter paper was not wetted, water droplets were formed Filter paper was not wetted, water droplets were still present Excellent Example 2 Filter paper was not wetted, water droplets were formed Filter paper was not wetted, water droplets were still present Excellent Example 3 Filter paper was not wetted, water droplets were formed Filter paper was not wetted, water droplets were still present Excellent Example 4 Filter paper was not wetted, water droplets were formed Filter paper was not wetted, water droplets were still present Excellent Example 5 Filter paper was not wetted, water droplets were formed Filter paper was partially wetted, a small amount of water droplets were present Fair Example 6 Filter paper was not wetted, water droplets were formed Filter paper was not wetted, water droplets were still present Excellent Example 7 Filter paper was not wetted, water droplets were formed Filter paper was not wetted, water droplets were still present Excellent Example 8 Filter paper was not wetted, water droplets were formed Filter paper was not wetted, water droplets were still present Excellent Comparative Example 1 Filter paper was not wetted, water droplets were formed Filter paper was partially wetted, a small amount of water droplets were present Fair Comparative Example 2 Filter paper was not wetted, water droplets were formed Filter paper was partially wetted, a small amount of water droplets were present Fair Comparative Example 3 Filter paper was not wetted, water droplets were formed Filter paper was partially wetted, a small amount of water droplets were present Fair Comparative Example 4 Filter paper was not wetted, water droplets were formed Filter paper was partially wetted, a small amount of water droplets were present Fair Comparative Example 5 Filter paper was not wetted, water droplets were formed Filter paper was partially wetted, a small amount of water droplets were present Fair

[0104] Test item 3: sensory evaluation

[0105] Test method

[0106] Using the sensory evaluation method of the test personnel, 0.1mg of diaper rash cream is evenly applied to the inside of the tester's (not less than 5) arm 5.0cmx5.0cm square area, and the skin's load feeling is evaluated, scoring from 1 to 10, with 10 points for skin feeling very light and easy to spread, no oil light, no sticky, no burden feeling. Take the average value of the test personnel. The test results are shown in Table 6.

[0107] Table 6 Sensory evaluation results

[0108]

[0109] Test item 4: low temperature hardness performance test

[0110] Test method

[0111] Fill the diaper rash cream samples into the same package, then place them in a refrigerator at a temperature of 4±1℃, take out the samples after 48 hours, observe the difficulty of the cream body extrusion when it is taken out, and observe the hardness of the cream body.

[0112] The extrusion performance of diaper rash cream at low temperature is shown in Table 7.

[0113] Table 7 Test results of low temperature hardness performance

[0114]

[0115]

[0116] Test item 5: high temperature performance test

[0117] The nappy cream samples were filled into the same packaging material, and then placed in an oven at 60±1°C for 24 hours. After taking out the samples, the hardness of the cream body and whether the cream was layered were observed.

[0118] The high temperature performance of the nappy cream was as shown in Table 8.

[0119] Table 8: Results of high temperature performance test

[0120]

[0121] Test item 6: soothing redness test

[0122] Test method: First, 2% SDS was used to artificially model, and a small frame of 2x2 was cut. 20ul of SDS was added to each small chamber, and the patch tester was attached to the back. The next day, the patch tester was removed, and the subject was asked to sit quietly for 30 minutes at the required temperature. During this time, the subject was not allowed to walk or eat, and the test site was exposed. The subject was asked to remain relaxed, and the test area, sample area and control area were randomly allocated according to the blinding table. After 30 minutes, the SDS modeling was visually judged. If there were more than 2 obvious red spots in each area, the red pigment content at T0 was directly collected. The collection method was to mark the two smallest frames in each area that were visually the reddest as the data collection area. After completing data collection, the staff followed the blinding table to apply the sample to each area. If the subject's arm modeling area had no obvious red spots, the skin barrier was damaged by using a low-sensitization adhesive tape and DMSO stimulation (4cm x 4cm, 30ul of DMSO was applied, and the reaction lasted for more than 30 minutes, and then the skin was washed with water).

[0123] After completing sample application (2h, 4h): The test area of the subject was determined by the same laboratory technician, and the data was recorded.

[0124] The experimental results can be seen in Table 9.

[0125] Table 9: Results of soothing redness test

[0126]

[0127]

[0128] The data of Tables 4 to 9 above were summarized and analyzed, and the summary results can be seen in Table 10.

[0129] Table 10: Test results

[0130]

[0131] Results analysis:

[0132] 1. From the test results of 4h soothing redness fading, examples 2, 3, 4 are the best, there are two factors: one is the amount of active ingredients, the other is the selection of active ingredients, through the results of multiple cases, the amount generally needs to reach 0.2% or more, and at least has hardening alcohol glycyrrhizin acid ester and at least one of bisabolol, yunnan baiyao leaf extract is the best;

[0133] 2. From the test results of contact angle, examples 2, 6-8 are better, and example 5 is the best; further combined with the test results of example 6 and comparative example 1, we can be more sure that lanolin is helpful to improve the instant contact angle of the nappy cream.

[0134] From the test results of comparative example 2, comparative example 3, comparative example 4 and example 6, it can be seen that trihydroxy stearyl, microcrystalline wax, white beeswax are also very important for good contact angle.

[0135] From the test results of comparative example 5 and example 6, it can be seen that the amount of petrolatum needs to be kept more than light weight polar synthetic oil;

[0136] 3. From the test results of nappy cream urine isolation effect, all comparative examples are worse than example 6, which shows that lanolin, trihydroxy stearyl, microcrystalline wax, white beeswax and the ratio of main ingredients all have an impact on urine isolation performance; Each case in the example has good performance, except for example 5, which shows that with the increase of lanolin addition amount, the long-term urine isolation effect will decrease.

[0137] The possible synergistic mechanism of the above in terms of urine isolation performance is that lanolin raw material itself has certain viscosity, which is speculated to fix liquid drops immediately when it comes into contact with urine, slowing down the diffusion speed of liquid drops, but lanolin itself has good water absorption, which will absorb urine over time, affecting the urine isolation effect. The increase in the amount of addition will increase the amount of water absorption, which will affect the long-term urine isolation effect of the diaper rash cream. The use of the inherent properties of lanolin raw materials can help improve the urine isolation performance; trihydroxy stearyl ester, mineral oil and ethylhexyl stearate can form a crystalline molecular network structure, which helps to stabilize the compatibility of each component and ensures the uniformity of the diaper rash cream film. Under high temperature shear, the molecules stretch and expand to an inflated state, which can well suspend light synthetic oils and lanolin with low melting point, ensuring the durability of the film. Based on the high humidity and stuffy environment of infants using diapers for a long time, the addition of trihydroxy stearyl ester is necessary to improve the urine isolation performance under high temperature conditions. In addition, microcrystalline wax and white beeswax can form a stable and uniform cream with light polar synthetic oils, mineral oil and other active ingredients, which has good adhesion and spreadability, and helps to improve the uniformity and durability of the diaper rash cream film, and can synergistically enhance the urine isolation performance.

[0138] 4. From the change of the hardness of the diaper rash cream at different temperatures, i.e. high and low temperature performance data, it can be seen that there are obvious differences among the examples, among which examples 2, 6-8 are excellent; the reason why the high and low temperature performance of example 1 is poor is that as the amount of trihydroxy stearyl ester increases, the space for stretching of the molecular network structure is limited, the network structure is dense, which reduces the flexibility of the diaper rash cream, and the cream as a whole is hard. In addition, the increase in the amount of microcrystalline wax and white beeswax will increase the melting point of the cream, making the cream hard. The increase in the amount of oil absorbing raw materials will absorb more liquid oil, making the cream thick and hard to spread. The reason why the low temperature performance of examples 4 to 5 is general is that as the amount of white beeswax and microcrystalline wax increases in examples 4 and 5, the cream has a strong waxiness under low temperature conditions, and the cream as a whole appears slightly hard. The reason why the high temperature performance of examples 3 to 4 is general is that the decrease in the amount of white beeswax in example 3 will reduce the melting point of the cream, making it slightly flowable under high temperature conditions. The increase in the amount of liquid oil in example 4 will reduce the melting point of the cream, making it slightly flowable under high temperature conditions, so the high temperature performance is general.

[0139] In addition, the high temperature performance data of comparative examples 1-5 shows that they are all poor, which shows the importance of lanolin, trihydroxy stearyl ester, microcrystalline wax and white beeswax for the hardness of the diaper rash cream at different temperatures, and they are indispensable;

[0140] Considering the contact angle, overall sensory score, long-term urine isolation effect, high and low temperature performance and soothing redness reduction effect, example 2 is the best.

[0141] It will be apparent to those skilled in the art that the application is not limited to the details of the above-exemplified embodiments and that the present application can be implemented in other particular forms without departing from the spirit or essential characteristics of the present application. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the application being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. No reference signs in the claims shall be construed as limiting the scope of the claims.

Claims

1. A diaper rash cream, characterized in that, Includes the following components by weight percentage: Mineral oil: 49.6~50.3%; Light polar synthetic oils: 40%; Lanolin: 5%; Trihydroxystearin: 2%; Microcrystalline wax: 1%; Oil-absorbing powder: 1%; White beeswax: 0.7%; The light polar synthetic oil is ethylhexyl stearate and / or caprylic / capric triglyceride.

2. The diaper rash cream according to claim 1, characterized in that, It also includes 0.1% to 1% macadamia nut oil.

3. The diaper rash cream according to claim 1, characterized in that, The oil-absorbing powder is aluminum octenyl succinate starch and / or boron nitride.

4. The diaper rash cream according to claim 1, characterized in that, It also includes redness-reducing and soothing ingredients; the redness-reducing and soothing ingredients are one or more of stearyl glycyrrhizate, bisabolol, and centella asiatica leaf extract.

5. The diaper rash cream according to claim 4, characterized in that, The amount of the redness-reducing and soothing ingredient is 0.1-1.5%.

6. The diaper rash cream according to claim 1, characterized in that, It also includes an active ingredient for inhibiting urease activity; the active ingredient is pomegranate peel extract and / or quercetin; the amount of the active ingredient is 0.001~0.01%.

7. A method for preparing a diaper rash cream as described in claim 1, characterized in that, Includes the following steps: Step 1: Mix petrolatum, light polar synthetic oils, lanolin, trihydroxystearin, microcrystalline wax, and white beeswax, heat until melted, and homogenize; Step 2: Cool to 55~70℃ and stir to homogenize; Step 3: Add oil-absorbing powder to Step 2, stir to homogenize, and then cool and discharge.

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