Traditional Chinese medicine preparation for treating wind-heat type common cold and preparation method thereof

Abstract

The invention relates to a traditional Chinese medicine preparation for treating wind-heat type common cold. The traditional Chinese medicine preparation is prepared from gypsum, rhizoma anemarrhenae, honeysuckle, fructus forsythiae, radix isatidis, folium isatidis, laggera pterodonta, radix bupleuri, radix scutellariae, rhizoma coptidis, radix puerariae, bamboo leaves, dandelion, herba patriniae, fructus xanthii, flos magnoliae liliflorae, radix angelicae, rhizoma phragmitis, radix arnebiae seu lithospermi, radix platycodonis, bombyx batryticatus, cortex lycii radicis, wax gourd kernels, radix saposhnikoviae, radix paeoniae rubra, indigo naturalis, coix seeds, Chinese yam, rice sprouts, hawthorn fruits, hyacinth beans, centipeda minima, herba schizonepetae, mint, almonds, perilla leaves, fresh ginger and liquorice. The medicament is prepared from 38 raw medicinal materials. The used medicaments can be oral liquid, granules, powder, capsules, electuary and tablets. The preparation method comprises the following steps: extracting the medicines with water to prepare a concentrated solution, and preparing the concentrated solution into the traditional Chinese medicine preparation according to a conventional method. The raw material medicines adopted by the invention are common traditional Chinese medicines, are low in preparation cost and basically have no toxic or side effect. The traditional Chinese medicine composition has the advantages of quick response and high curative effect, can enhance the autoimmunity, and is suitable for various sudden, explosive, epidemic and influenza. The diseases can also be prevented and treated. The invention can be suitable for large-pot decoction, oral administration, fumigation and bath in large places, such as schools, troops, factories and mines and the like. And the traditional Chinese medicine composition is mainly used for treating various types of diseases such as wind heat, summer-heat dampness, influenza, rhinitis, mosquito bite injury and the like.

Description

Technical Field

[0001] The present invention relates to a medicine for treating wind-heat cold prepared from traditional Chinese medicines and its preparation method, specifically a traditional Chinese medicine preparation for treating wind-heat cold and its preparation method. Background Art

[0002] Wind-heat cold is a disease that occurs suddenly or breaks out and spreads, and is contacted through the respiratory tract, mouth, nose, hands, and objects (products) in the air and during personnel flow and enters the respiratory system. Wind-heat cold has become epidemic and is prone to mutation, often causing explosive epidemics or pandemics. The number of patients is large and the symptoms are severe. If not treated in time, it is easy to cause various diseases such as pneumonia, seriously affecting people's physical health. Traditional Chinese medicine believes that wind-heat cold is caused by the invasion of external pathogens and internal damp stasis, and the treatment method should start from treating the root cause. Currently, the incidence rate is relatively high. The main symptoms are relatively high body heat, slightly aversion to wind, unsmooth sweating, headache, nasal congestion, runny nose with yellow and turbid discharge, cough, thick and yellow phlegm, red and swollen throat, thirst and preference for drinking, red tip and edges of the tongue, thin and slightly yellow tongue coating, floating and rapid pulse and other general symptoms, often accompanied by high fever and a relatively long course of disease. Especially in the elderly and weak groups and children with low resistance, if not treated in time, it will induce the original underlying diseases and seriously affect people's physical health. In ancient and modern times, the predecessors in the medical field have summarized and improved the experience of treating wind-heat cold, continuously summarizing and improving, striving to eliminate it in the initial stage and control the spread as much as possible. When treating wind-heat cold, traditional Chinese medicine must first distinguish whether it is influenza, identify the symptoms, and through modern advanced examination means, be timely, stable, accurate, fast and thorough. According to the principle of syndrome differentiation and treatment in traditional Chinese medicine, different types of colds should use different treatment drugs. For patients with strong constitutions and no underlying diseases in the initial stage, drugs with functions of clearing heat and detoxifying, relieving exterior syndrome with pungent and cool herbs, dispersing wind and clearing heat, relieving pain, promoting fluid production to quench thirst, and removing vexation should be used. Then, regulating the stomach and strengthening the spleen, soothing the liver and regulating qi, helping to restore physical strength, enhancing the body's anti-viral ability, and striving for an early recovery are the basic principles. Summary of the Invention

[0003] The purpose of the present invention is to provide a new traditional Chinese medicine preparation that can quickly treat wind-heat cold, specifically a technical solution for a traditional Chinese medicine preparation for treating wind-heat cold and its preparation method.

[0004] The technical solution of the present invention is a medicine for treating wind-heat cold, which is characterized in that it is a medicament prepared from the following raw medicinal materials in parts by weight:

[0005] Gypsum Fibrosum 9 - 12 Anemarrhena Rhizome 6 - 9 Lonicera Japonica Flower 6 - 9 Forsythia Fruit 4 - 8

[0006] Isatis Root 9 - 12 Folium Isatidis 9 - 12 Laggera Pterodonta 13 - 18 Bupleurum Root 4 - 9

[0007] Scutellaria Root 3 - 6 Coptis Rhizome 1 - 1.5 Pueraria Root 9 - 12 Bambusa Leaves 4.5 - 6

[0008] Taraxacum 4.5 - 6, Patrinia 4.5 - 6, Xanthium 3 - 4.5, Magnolia Flower Bud 4.5 - 9

[0009] Angelica Dahurica 6 - 9, Reed Root 6 - 9, Lithospermum 4.5 - 6, Platycodon Root 4.5 - 6

[0010] Bombyx Batryticatus 6 - 9, Lycium Root - Bark 6 - 9, Benincasa Seed 4.5 - 6, Saposhnikovia Root 6 - 9

[0011] Red Peony Root 6 - 9, Indigo Naturalis 1 - 1.5, Coix Seed 25 - 35, Chinese Yam 13 - 18

[0012] Fructus Setariae Germinatus 6 - 12, Hawthorn Fruit 4.5 - 6, Hyacinth Bean 13 - 18, Herba Centipedae 3 - 12

[0013] Schizonepeta 3 - 9, Mentha 3 - 9, Apricot Kernel 3 - 9, Perilla Leaf 3 - 9

[0014] Ginger 3 - 9, Licorice Root 3 - 5

[0015] The said medicament is oral liquid, granule, powder, capsule, medicinal extract, tablet.

[0016] A preparation method of a drug for treating wind - heat cold, characterized by comprising the following steps;

[0017] (1) Extract the drug described in claim 1 with water,

[0018] (2) Make it into a concentrated liquid with a water content of 10%,

[0019] (3) Make it into a traditional Chinese medicine preparation by conventional methods.

[0020] The said traditional Chinese medicine preparation is oral liquid. Add excipients to the concentrated liquid by conventional methods to make an oral liquid for treating wind - heat cold.

[0021] The said traditional Chinese medicine preparation is powder. Concentrate, dry and pulverize the concentrated liquid by conventional methods to make a powder for treating wind - heat cold.

[0022] The said traditional Chinese medicine preparation is granule. Add excipients to the powder by conventional methods to make a granule for treating wind - heat cold.

[0023] The said traditional Chinese medicine preparation is capsule. Make the powder into a capsule for treating wind - heat cold by conventional methods.

[0024] The said traditional Chinese medicine preparation is medicinal extract. Make the powder into a medicinal extract for treating wind - heat cold by conventional methods.

[0025] The said traditional Chinese medicine preparation is tablet. Make the powder into a tablet for treating wind - heat cold by conventional methods.

[0026] The present invention is summarized on the basis of traditional medicine through a large number of clinical trials. It can treat wind-heat cold, which is caused by external pathogenic qi of warmth, heat, high fever and fire poison, which injures qi and enters the camp. The heat poison of qi is blazing, and the heat of blood causes the virus to fill the inside and outside. The external evil is not resolved and spreads to the yangming qi, invading the camp and blood organs, and the "qi and blood are both burning", which is manifested by high fever, thirst, vomiting, epistaxis, rash, and coma and wandering in severe cases.

[0027] The invention takes gypsum and rhizoma anemarrhenae of the coldest season as the main ingredients, which are mainly used to treat the raging fire poison in the qi, and first calm the excess; it is matched with coptis chinensis and scutellaria baicalensis, which are bitter and cold, and jointly treat the heat poison in the lung and stomach; honeysuckle, forsythia, platycodon, bamboo leaf, reed root, and mint are the secondary ingredients, which are mainly used to treat the warm evil of wind-heat cold, dry mouth and sore throat, red tongue with yellow fur, and even oral sores, erosion and suppuration; it further uses isatis root, isatis indigotica, kudzu root, indigo, lycium bark, lithospermum officinale, and red peony root to clear away heat, cool blood, detoxify and quench thirst; magnolia flower, xanthium sibiricum, angelica dahurica, siler, schizonepeta tenuifolia, and perilla The leaves dispel wind and relieve the symptoms, open the nasal passages, and lead the pathogens out of the upper respiratory tract; Bombyx batryticatus, Patrinia scabra, Taraxacum officinale, wax gourd seeds, and apricot kernels clear away heat, detoxify, and promote urination, leading the pathogens out of the bladder; Bupleurum and Scutellaria baicalensis harmonize the Shaoyang meridians and eliminate the pathogens; Stinky Elsholtzia and Pueraria root work together to cool the throat, quench thirst, and promote the production of body fluids; Chinese yam, lentil, coix seed, and ginger are used to treat the spleen and stomach qi damaged by pathogens. Because the raw gypsum and other drugs in the prescription are very cold, they further punish the spleen yang, and they are used to moderate the excessive force to avoid damaging the spleen and stomach. Sweet and soothing the middle, awakening the spleen and stomach, so that the pathogens are removed without hindering the stomach. Platycodon grandiflorum is used to lead the medicine to the upper part of the mouth, nose, and throat, and has the effect of sailing the upper respiratory tract. Adding malt sprouts and hawthorns can help digestion, relieve stagnation, and relieve urgency, and licorice harmonizes the various drugs. The present invention has a unique compatibility, and many drugs are properly compatible. It has the advantages of clearing the fire of the main body, saving the water that is about to be exhausted, removing rheumatism, heat and toxic evil, strengthening the body and removing evil, and removing evil without hurting the body. The yang body of children is more than the original yang. If the wind, heat and toxic evil invade, it will add fuel to the fire, and the high fever will not subside. The present invention is used to treat the fever of wind-heat cold in children with significant efficacy. It is effective for large sores, sores on the head and face, appendicitis, intestinal carbuncle, hemorrhoids, fire eyes where the wind and heat evil go, and toothache. The raw material medicine used in the present invention is a commonly used common Chinese medicine, with low production cost and basically no toxic and side effects. The present invention takes effect quickly, has high efficacy, can enhance its own immunity, and is particularly suitable for treating wind-heat cold. The important difference between the present invention and other existing wind-heat cold medicines is that it has a significant effect on treating severe colds, viral wind-heat colds, epidemic wind-heat colds, high fever, and even wind-heat colds with high fever. The present invention is faster than infusion for fever caused by wind-heat colds, and has no toxic and side effects.

[0028] Clinical trial: The present invention was used to follow up and treat 576 cases of wind-heat cold, including 273 males, 203 females, aged 3-80 years old, and 378 children, 12-48 hours after onset.

[0029] Common symptoms of general wind-heat cold include sneezing, nasal congestion, runny nose, cough, sore throat, headache, etc. There are 417 cases with aversion to wind and fever, with body temperature ranging from 37.5 to 40°C, accompanied by dizziness, headache, weakness and soreness in the limbs and back, and general discomfort.

[0030] Traditional Chinese medicine diagnosis: internal heat and external cold, manifested as fever with slight aversion to cold, headache, general body aches, unsmooth sweating, thirst, nasal congestion, sore throat, cough, thin yellow tongue coating, red tip and edge of the tongue or red tongue with yellow coating, rapid or surging pulse. In severe cases, there are four major syndromes of high fever, profuse sweating, great thirst, and surging pulse.

[0031] Treatment method: Take 10 - 20 ml of the oral liquid each time, three times a day. For granules, powders, capsules, extracts, etc., take 3 - 10 grams each time, three times a day. The dosage for children is halved.

[0032] After taking the medicine for three days, among the patients with body temperature ranging from 37.5 to 40°C, 237 patients had completely subsided fever, with body temperature returning to normal and all clinical symptoms disappearing, and the total cure rate was 41.11%. 208 patients had significantly effective results, with completely subsided fever and basically disappeared clinical symptoms, and the total significant effective rate was 36.11%. 102 patients had effective results, with decreased body temperature but incomplete subsidence of fever, body temperature still higher than normal, and partial disappearance of clinical symptoms, and the total effective rate was 17.7%. 29 patients had no improvement in clinical symptoms, and the total ineffective rate was 0.503%. Among them, the average time for the fever to start subsiding was 7.35 hours, and the average time for complete subsidence of fever to normal was 24.24 hours. For teenagers, children and patients with strong constitutions, the average time for the fever to start subsiding was 5.30 hours, and the average time for complete subsidence of fever to normal was 22.24 hours. No obvious drug adverse reactions and toxic side effects were observed during the treatment process, indicating that the drug is relatively safe to take.

[0033] Precautions: It is prohibited for pregnant women, infants and patients with diarrhea. Elderly and weak patients should stop taking the medicine immediately after the fever subsides and should not continue taking it to avoid diarrhea due to spleen and stomach deficiency and cold. If the above symptoms occur, you can eat thin porridge or easily digestible foods to soothe the spleen and stomach. Specific implementation method

[0035] Extract the raw material medicine in the above proportion by water extraction and make it into a concentrated solution with a water content of 10%.

[0036] Add excipients to the concentrated solution by conventional methods to make an oral liquid for treating wind-heat cold with a water content of 5 - 8%. Concentrate, dry and pulverize the concentrated solution by conventional methods to make a powder for treating wind-heat cold, with each bag weighing 3 - 5 grams.

[0037] Add the powder to the adjuvant and prepare it into granules for treating wind-heat cold according to the conventional method, with each bag containing 3-5 grams of the medicinal powder.

[0038] Prepare the powder into capsules for treating wind-heat cold according to the conventional method, with each capsule containing 0.2-0.5 grams.

[0039] Prepare the powder into infusion for treating wind-heat cold according to the conventional method, with each bag containing 3-5 grams of the medicinal powder.

[0040] Prepare the powder into tablets for treating wind-heat cold according to the conventional method, with each tablet containing 0.2-0.5 grams of the medicinal powder.

Claims

1. A traditional Chinese medicine preparation for treating wind-heat cold, characterized in that it is a medicament prepared from the following raw medicinal materials in parts by weight:

2. The traditional Chinese medicine preparation for treating wind-heat cold according to claim 1, characterized in that the traditional Chinese medicine preparation is oral liquid, powder, capsule, granule, tablet.

3. The preparation method of the traditional Chinese medicine preparation for treating wind-heat cold according to claim 1, characterized in that it consists of the following steps: (1) Water-extracting the raw medicinal materials described in claim 1 (2) Preparing a concentrated solution with a water content of 10%, (3) Preparing the traditional Chinese medicine preparation by conventional methods.

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