Functional product composition for losing weight, shaping, dehumidifying and bodybuilding and preparation method thereof

Abstract

The functional product composition is prepared from the following medicinal materials in parts by weight: 1 to 375 parts of pericarpium citri reticulatae, 3 to 1000 parts of raw radix astragali seu hedysari, 1 to 450 parts of folium nelumbinis, 1 to 450 parts of herba pogostemonis, 1 to 225 parts of fructus foeniculi, 2 to 450 parts of fructus corni, 1 to 300 parts of rhizoma zingiberis recens, 0.5 to 150 parts of cortex cinnamomi, 0.5 to 135 parts of flos caryophylli and 2 to 600 parts of fructus cannabis. According to the invention, the problem of dysfunction of obesity among multiple dimensions and multiple viscera can be solved, so that radical conditioning is carried out, various health problems caused by obesity are fundamentally solved, and obese people can recover health and enhance vitality in the weight loss process. The invention further discloses a preparation method of the functional product for losing weight, shaping, dehumidifying and building body.

Description

Technical Field

[0001] The present invention relates to a functional product, specifically to a functional composition of medicated diet homologous for weight loss and body shaping, dehumidification and bodybuilding. The present invention also relates to a preparation method of a functional composition of medicated diet homologous for weight loss and body shaping, dehumidification and bodybuilding. Background Art

[0002] At present, the dietary structure is unreasonable, the intake proportion of high-oil and high-sugar foods is relatively large, and life is comfortable, physical labor is reduced, work is sedentary for a long time, lack of exercise, and the calories consumed in eating are often greater than the calories consumed, resulting in an increase in the body fat content and even becoming an obese body shape.

[0003] In recent years, the weight loss market in China has shown explosive growth. The market scale has exceeded the 100 billion level in 2023 and is expected to exceed 200 billion yuan in 2025. Online channels (such as e-commerce platforms) have become the main growth engine. The market scale of functional weight loss foods reached 338.71 billion yuan in 2022, with a year-on-year growth of 21.2%. The market demand continues to expand.

[0004] Research has found that most obese people not only have fat accumulation inside and outside the body, but also their physical fitness deteriorates. Therefore, developing products that can not only effectively control weight, reshape body shape, but also balance the body's internal organs, create an internal ecosystem, establish a healthy environment, maintain the body balance, and have no toxic side effects will solve the pain of more people.

[0005] Existing weight loss products mainly include chemically synthesized drugs, meal replacement foods and exercise assistance products.

[0006] Chemically synthesized drugs may have side effects. For example, orlistat, bupropion, etc. may cause adverse reactions such as diarrhea, palpitations, insomnia, increased blood pressure, etc., and long-term use may damage the liver and kidneys. Some drugs achieve the effect by suppressing appetite or accelerating metabolism. After stopping use, it is easy to rebound, and even lead to metabolic disorders.

[0007] The effect of meal replacement foods is limited. Long-term dependence on meal replacements may lead to insufficient intake of vitamins, minerals or proteins, causing malnutrition. The monotonous taste and dietary restrictions are likely to lead to psychological resistance, and weight is easy to rebound after resuming normal diet. Some products exaggerate the effects of "low calories" or "high fiber", but actually may contain hidden sugars or additives.

[0008] Exercise assistance products require long-term adherence, and the effect depends on self-discipline. The equipment only provides data monitoring (such as calorie consumption), and cannot force users to adhere to exercise or a healthy diet. The heart rate and calorie consumption measurement errors of some equipment are relatively large, which may lead to users misjudging the effect. "Vibration belts", "abdominal slimming devices", etc. claim to reduce local fat, but it cannot be achieved scientifically.

[0009] Most existing weight loss techniques fail to address the fundamental contradiction, namely the balance between short-term effects and long-term health. Most products only treat the symptoms rather than the root cause, and lack personalized interventions for metabolic syndrome (such as insulin resistance). Traditional Chinese medicine has unique advantages in weight loss, but existing Chinese medicine weight loss products mostly have problems such as complex ingredients, unclear effects, and inconvenient administration. Therefore, there is an urgent need for a safe, effective, and easy-to-take Chinese medicine weight loss product. Summary of the Invention

[0010] The technical problem to be solved by the present invention is to provide a functional medicine and food homologous composition for weight loss, shaping, reducing dampness and promoting health. It can not only effectively control weight, but also fundamentally solve various health problems brought by obesity, enabling obese people to regain health and enhance vitality during the weight loss process.

[0011] To solve the above technical problem, the technical solution of the functional medicine and food homologous composition for weight loss, shaping, reducing dampness and promoting health of the present invention is as follows:

[0012] Prepared from the following medicinal materials in parts by weight:

[0013] Tangerine peel 1 - 375 parts, Astragalus membranaceus 3 - 1000 parts, Lotus leaf 1 - 450 parts, Pogostemon cablin 1 - 450 parts, Fennel 1 - 225 parts, Cornus officinalis 2 - 450 parts, Ginger 1 - 300 parts, Cinnamon 0.5 - 150 parts, Clove 0.5 - 135 parts, Cannabis seed 2 - 600 parts.

[0014] In another embodiment, the composition further comprises a pharmaceutically acceptable carrier.

[0015] The present invention also provides a preparation method of a functional medicine and food homologous product granule for weight loss, shaping, reducing dampness and promoting health. Its technical solution is as follows, including the following steps:

[0016] (1) Weigh the medicinal materials according to the following weight ratio, and wash them clean;

[0017] Tangerine peel 1 - 25 parts, Astragalus membranaceus 3 - 70 parts, Lotus leaf 1 - 30 parts, Pogostemon cablin 1 - 30 parts, Fennel 1 - 15 parts, Cornus officinalis 2 - 30 parts, Ginger 1 - 18 parts, Cinnamon 0.5 - 10 parts, Clove 0.5 - 9 parts, Cannabis seed 2 - 40 parts;

[0018] (2) Dry the medicinal materials and grind them into powder;

[0019] (3) After fully mixing the medicinal material powder, perform high-temperature sterilization and disinfection;

[0020] (4) Add excipients, form and granulate to form particulate matter;

[0021] (5) Perform high-temperature sterilization and disinfection again to obtain the product.

[0022] In another embodiment, a pharmaceutically acceptable carrier is further included in the step (1).

[0023] The present invention also provides a preparation method of a functional medicated diet homologous product paste for weight loss and body shaping, and dehumidification and body building. The technical solution is as follows: it includes the following steps:

[0024] (1) Weigh the medicinal materials according to the following weight ratios, wash them cleanly, decoct them strongly to remove the residues, and obtain the concentrated juice;

[0025] 5 - 375 parts of dried tangerine peel, 6 - 1000 parts of astragalus membranaceus, 5 - 450 parts of lotus leaf, 5 - 450 parts of pogostemon cablin, 5 - 225 parts of fennel, 9 - 450 parts of cornel, 5 - 300 parts of ginger, 3 - 150 parts of cinnamon, 3 - 135 parts of cloves, 6 - 600 parts of hemp seeds;

[0026] (2) Add 200 - 500 parts of fructooligosaccharide, melt and collect the paste to obtain the product.

[0027] In another embodiment, a pharmaceutically acceptable carrier is further included in the step (1).

[0028] The present invention also provides the use of a functional medicated diet homologous composition in the preparation of a functional product for assisting in weight loss and body shaping, and dehumidification and body building.

[0029] The technical effects that the present invention can achieve are as follows:

[0030] The present invention can skillfully resolve many factors that lead to disharmony of the spleen and stomach transportation and transformation, whether it is liver qi attacking the spleen, spleen and stomach qi deficiency, or kidney yang deficiency, spleen and stomach stagnation, or pathogenic factors such as phlegm - dampness, damp - heat, accumulation, cold qi, internal heat, etc. Because of this unique advantage, when the present invention is applied, there is no need for complex syndrome differentiation and treatment, and as long as it is a patient with obesity, it can be used.

[0031] The present invention can solve the problem of functional disorders of obesity in multiple dimensions and multiple zang - fu organs, so as to carry out radical conditioning, thereby fundamentally solving various health problems brought about by obesity, and enabling obese people to recover health and enhance vitality during the weight loss process.

[0032] Obesity is a superficial phenomenon, while the disorder of the spleen and stomach functions is the fundamental cause of obesity. The transportation and transformation functions of the spleen are related to the whole process of human life, and are closely related to life activities such as the continuation of life, physiological needs, maintenance of health, and the level of health, which is extremely important. Because of this, "Huangdi Neijing" says: "The spleen is the foundation of acquired constitution." "Huangdi Neijing" believes that human life and health are jointly determined by the five zang-organs. This invention firmly grasps the pathogenesis of obesity and particularly focuses on the core element of the overall health status of the five zang-organs, thus solving the functional disorders of obesity in multiple dimensions and multiple zang-organs. Through this radical conditioning method, this invention can not only effectively control weight, but also fundamentally solve various health problems brought about by obesity, enabling obese people to recover health and enhance vitality during the weight loss process.

[0033] This invention has four major value characteristics: ① General treatment formula: It does not require complex syndrome differentiation and treatment, and can be used by various obese patients. ② No special diet control: When taking it, weight loss people do not need to specially restrict their diet, achieving real healthy weight loss. ③ No fatigue: This invention not only helps with weight loss, but also improves the mental state of weight loss people, making the weight loss process a real health reshaping process. ④ No diarrhea: This invention focuses on regulating the health status of the spleen and stomach and will not cause adverse reactions such as diarrhea.

[0034] This invention belongs to a medicine-food homologous composition. All the drugs in the whole formula are traditional Chinese medicines that are both medicine and food. They are safe and effective for consumption, extremely easy to promote and carry, and have broad market prospects. Detailed implementation methods

[0035] To make the objectives, technical solutions, and advantages of the embodiments of this invention clearer, the technical solutions of the embodiments of this invention will be clearly and completely described below. Obviously, the described embodiments are part of the embodiments of this invention, rather than all of them. Based on the described embodiments of this invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the scope of protection of this invention. Unless otherwise defined, the technical terms or scientific terms used herein shall have the ordinary meaning understood by those of ordinary skill in the art in the field to which this invention belongs. The words "first", "second", and similar words used herein do not indicate any order, quantity, or importance, but are only used to distinguish different components. Words such as "including" mean that the elements or objects appearing before this word cover the elements or objects listed after this word and their equivalents, without excluding other elements or objects.

[0036] This invention is a functional medicine-food homologous composition for weight loss, body shaping, reducing dampness and promoting beauty, and is prepared from the following medicinal materials in parts by weight:

[0037] 1 - 375 parts of dried tangerine peel, 3 - 1000 parts of astragalus membranaceus, 1 - 450 parts of lotus leaf, 1 - 450 parts of agastache rugosa, 1 - 225 parts of fennel, 2 - 450 parts of cornel, 1 - 300 parts of ginger, 0.5 - 150 parts of cinnamon, 0.5 - 135 parts of clove, 2 - 600 parts of cannabis seed.

[0038] The composition further comprises a pharmaceutically acceptable carrier.

[0039] The preparation method of the granule of the functional medicine and food homologous product for weight loss, body shaping, dehumidification and body building of the present invention comprises the following steps:

[0040] (1) Weigh the medicinal materials according to the following weight ratio, and wash them clean;

[0041] 1 - 25 parts of dried tangerine peel, 3 - 70 parts of astragalus membranaceus, 1 - 30 parts of lotus leaf, 1 - 30 parts of agastache rugosa, 1 - 15 parts of fennel, 2 - 30 parts of cornel, 1 - 18 parts of ginger, 0.5 - 10 parts of cinnamon, 0.5 - 9 parts of clove, 2 - 40 parts of cannabis seed;

[0042] (2) Dry the medicinal materials and grind them into powder;

[0043] (3) After fully mixing the medicinal material powder, perform high-temperature sterilization;

[0044] (4) Add excipients, form and granulate to form particulate matter;

[0045] (5) Perform high-temperature sterilization again to obtain the product.

[0046] The preparation method of the medicated ointment of the functional medicine and food homologous product for weight loss, body shaping, dehumidification and body building of the present invention comprises the following steps:

[0047] (1) Weigh the medicinal materials according to the following weight ratio, wash them clean, decoct them strongly to remove the residue, and take the concentrated juice;

[0048] 5 - 375 parts of dried tangerine peel, 6 - 1000 parts of astragalus membranaceus, 5 - 450 parts of lotus leaf, 5 - 450 parts of agastache rugosa, 5 - 225 parts of fennel, 9 - 450 parts of cornel, 5 - 300 parts of ginger, 3 - 150 parts of cinnamon, 3 - 135 parts of clove, 6 - 600 parts of cannabis seed;

[0049] (2) Add 200 - 500 parts of fructooligosaccharide, melt and collect the ointment to obtain the product.

[0050] Preferably, it further comprises a pharmaceutically acceptable carrier.

[0051] The effects of each component of the present invention are as follows:

[0052] (1) Dried tangerine peel

[0053] It is the mature and dried pericarp of the plant Citrus reticulata Blanco of the Rutaceae family and its cultivated varieties.

[0054] Weight loss-related effects:

[0055] Promote digestion: The volatile oils (such as limonene) in tangerine peel can stimulate gastrointestinal peristalsis, help digest food, and reduce fat accumulation.

[0056] Dry dampness and resolve phlegm: Tangerine peel can eliminate damp phlegm in the body and improve obesity caused by internal obstruction of damp phlegm.

[0057] Regulate blood lipids: The flavonoid components in tangerine peel can reduce the levels of serum cholesterol and triglycerides.

[0058] Mechanism of weight loss action:

[0059] Accelerate fat decomposition and metabolism by promoting bile secretion.

[0060] Inhibit the activity of fat synthase and reduce fat production.

[0061] (2) Astragalus membranaceus

[0062] It is the root of the plants Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao and A. membranaceus (Fisch.) Bge. of the Leguminosae family.

[0063] Weight loss-related effects:

[0064] Enhance metabolism: Astragalus polysaccharide can increase the basal metabolic rate and promote energy consumption.

[0065] Induce diuresis and alleviate edema: Astragalosides have a diuretic effect and can eliminate edema-type obesity.

[0066] Regulate blood sugar: Astragalus membranaceus can improve insulin sensitivity and contribute to weight control.

[0067] Mechanism of weight loss action:

[0068] Promote fat oxidation and energy consumption by activating the AMPK (Adenosine 5‘-monophosphate (AMP)-activated protein kinase) signaling pathway.

[0069] Inhibit adipocyte differentiation and reduce fat accumulation.

[0070] (3) Lotus leaf

[0071] It is the leaf of the lotus.

[0072] Weight loss-related effects:

[0073] Lipid-lowering and weight loss: Nuciferine can inhibit fat absorption and reduce the accumulation of body fat.

[0074] Clearing heat and promoting diuresis: Lotus leaf can eliminate internal damp-heat and improve damp-heat type obesity.

[0075] Antioxidation: Lotus leaf polyphenols can scavenge free radicals and improve metabolic syndrome.

[0076] Mechanism of weight loss action:

[0077] By inhibiting the activity of pancreatic lipase, fat absorption is reduced.

[0078] Regulate the expression of genes related to lipid metabolism and promote fat decomposition.

[0079] (4) Pogostemon cablin

[0080] It is the aerial part of Pogostemon cablin (Blanco) Benth. of the Lamiaceae family.

[0081] Weight loss-related effects:

[0082] Promote digestion: The volatile oil in Pogostemon cablin can stimulate the secretion of digestive juices and help digest food.

[0083] Transform dampness and regulate the middle energizer: Pogostemon cablin can eliminate internal dampness and improve obesity caused by dampness obstructing the middle energizer.

[0084] Antibacterial and anti-inflammatory: The extract of Pogostemon cablin can inhibit harmful intestinal bacteria and improve intestinal health.

[0085] Mechanism of weight loss action:

[0086] By regulating the intestinal flora, the intestinal metabolic function is improved.

[0087] Inhibit the release of inflammatory factors and reduce metabolic disorders caused by chronic inflammation.

[0088] Pogostemon cablin and its different chemical components can affect the glucose metabolism function of mice by adjusting and changing metabolic pathways and maintain the stability of liver glucose content.

[0089] (5) Fennel

[0090] It is the dried ripe fruit of Foeniculum vulgare Mill. of the Umbelliferae family.

[0091] Weight loss-related effects:

[0092] Regulate qi and harmonize the middle energizer: Fennel can relieve gastrointestinal flatulence and promote digestion.

[0093] Disperse cold and relieve pain: Fennel can improve cold constitution and promote blood circulation.

[0094] Anti-inflammatory: The extract of fennel can inhibit the inflammatory response and improve metabolic health.

[0095] Mechanism of weight loss:

[0096] By promoting gastrointestinal motility, accelerating food digestion and excretion.

[0097] Inhibit adipocyte inflammation and improve insulin resistance.

[0098] (6) Cornus officinalis

[0099] It is the mature sarcocarp of Cornus officinalis Sieb. et Zucc. of the family Cornaceae.

[0100] Weight loss-related effects:

[0101] Benefiting the liver and kidney: Cornus officinalis can improve liver and kidney functions and promote the excretion of metabolic wastes.

[0102] Regulating immunity: Cornus officinalis polysaccharide can enhance immune function and improve metabolic health.

[0103] Antioxidant: The iridoid components in Cornus officinalis can scavenge free radicals and delay aging. Mechanism of weight loss:

[0104] By regulating the hypothalamic-pituitary-adrenal axis, improving energy metabolism.

[0105] Inhibit adipocyte differentiation and reduce fat accumulation.

[0106] (7) Ginger

[0107] It is the fresh rhizome of Zingiber officinale Rose. of the family Zingiberaceae. Weight loss-related effects:

[0108] Warming the middle-jiao to stop vomiting: Ginger can promote gastrointestinal motility and help digest food.

[0109] Dispelling cold and relieving exterior syndrome: Ginger can improve cold constitution and promote blood circulation.

[0110] Anti-inflammatory: Ginger extract can inhibit the inflammatory response and improve metabolic health.

[0111] Mechanism of weight loss:

[0112] By activating TRPV1 receptor, promoting fat oxidation and energy consumption.

[0113] Inhibit adipocyte inflammation and improve insulin sensitivity.

[0114] (8) Cinnamon

[0115] It is the dried bark of the plant Cinnamomum cassia Presl in the Lauraceae family.

[0116] Weight loss-related effects:

[0117] Warming the meridian and promoting blood circulation: Cinnamon can improve blood circulation and promote metabolism.

[0118] Lowering blood sugar: Cinnamon polysaccharide can improve insulin sensitivity and contribute to weight control. Antioxidation: Cinnamon polyphenols can scavenge free radicals and improve metabolic syndrome.

[0119] Mechanism of weight loss action:

[0120] By activating the AMPK signaling pathway, it promotes fat oxidation and energy consumption.

[0121] (9) Clove

[0122] It is the dried flower buds of the plant Eugenia caryophyllata Thunb. in the Myrtaceae family.

[0123] Weight loss-related effects:

[0124] Weight loss: Through controlled experiments, it was found that traditional Chinese medicine clove has an obvious effect of preventing obesity in experimental animals, treating obesity, and reducing the weight of obese patients.

[0125] Warming the middle-jiao and reducing adverse qi: Clove can relieve gastrointestinal spasms and promote digestion.

[0126] Antibacterial: Clove extract can inhibit harmful intestinal bacteria and improve intestinal health.

[0127] Antioxidation: Clove polyphenols can scavenge free radicals and delay aging.

[0128] Mechanism of weight loss action:

[0129] It can inhibit the activities of pancreatic lipase and α-glucosidase, up-regulate the expression level of the low-density lipoprotein receptor mNRA in the body, and enhance the activity of LDLR (Low-Density Lipoprotein Receptor) / Luc luciferase.

[0130] By regulating the intestinal flora, it improves intestinal metabolic function.

[0131] Inhibits fat cell inflammation and improves insulin resistance.

[0132] Inhibits fat cell differentiation and reduces fat accumulation.

[0133] (10) Hemp seeds

[0134] It is the dried and mature fruits of the plant Cannabis sativa L. in the Moraceae family.

[0135] Weight loss-related effects:

[0136] Laxative effect: Hemp seeds can lubricate the intestines, relieve constipation, and promote the excretion of toxins.

[0137] Nourishing yin and tonifying deficiency: Hemp seeds are rich in unsaturated fatty acids, which helps improve blood lipid metabolism.

[0138] Anti-inflammatory: The extract of hemp seeds can inhibit inflammatory reactions and improve metabolic health.

[0139] Mechanism of weight loss:

[0140] By promoting intestinal peristalsis, accelerating food digestion and excretion.

[0141] Regulating the gene expression related to lipid metabolism and promoting fat decomposition.

[0142] Obesity constitutes a disease because it brings many harms and various health problems to the human body. The main problem lies in the disorder of the transportation and transformation function of the spleen. From the perspective of traditional Chinese medicine theory, there are two directions: First, if there is too much accumulation, obesity will form; Second, if there is excessive consumption, emaciation will form. The same pathogenesis of these two directions is caused by the failure of the spleen to function normally. The formation of obesity is a phenomenon caused by the long-term disharmony of the spleen and stomach functions, and even the disharmony of the liver and spleen functions, and the liver and stomach functions. Obesity is a phenomenon, and the disharmony of the spleen and stomach functions is the fundamental pathogenesis of obesity. In traditional Chinese medicine theory, the spleen and stomach are the key organs for digestion and absorption. Once they are disordered, it will lead to poor nutrient absorption and the accumulation of water and fat, and then obesity will form. Traditional rapid weight loss methods, such as restricting calorie intake or using laxatives, are effective in the short term but not sustainable, and are likely to damage the spleen and stomach functions, causing malnutrition and weight rebound.

[0143] The present invention not only focuses on the weight loss effect, but also pays more attention to the overall health during the weight loss process, ensuring that every obese friend can comprehensively restore and improve their health level while losing weight. In the formula, tangerine peel is the monarch drug that plays a leading and directional role. Tangerine peel mainly plays a neutralizing role in the middle jiao, not only has the effect of soothing the liver, regulating qi and relieving depression, but more importantly, has the effect of "harmonizing the middle". Then, astragalus membranaceus is directly used to replenish qi and enhance the transportation and transformation ability of the spleen. Qi itself is energy, which can generate kinetic energy, directly assisting the function of the spleen and enhancing the transportation and transformation function of the spleen. While replenishing qi, astragalus membranaceus also has the effect of transforming essence and blood, which is the ability of transportation and transformation. The present invention not only enhances the transportation and transformation ability of the spleen, but also provides the material components for tonifying qi and blood. It not only tonifies and enhances it in terms of function, but also supplements it in terms of substance. Then, the transportation and transformation function of the spleen will be correspondingly strengthened and improved. Lotus leaf has been used for weight loss since ancient times. It not only has the effect of weight loss, but also has a very good maintenance effect on the human skin. Here, the lotus leaf complements the functions of harmonizing the middle (tangerine peel) and enhancing the spleen and stomach (astragalus membranaceus). The lotus leaf is equivalent to building a water channel for the human body, allowing excess water to drain out through this channel. Agastache rugosa is also diuretic here. Based on the lotus leaf, it further drains out part of the water that has not been filtered clean on the epidermis or has not been discharged in the water channel. Fennel and ginger together assist the lotus leaf and agastache rugosa to further resolve the dampness in the body and relieve the state of internal obstruction of phlegm-dampness. Cornus officinalis can tonify essence, replenish qi, and also enhance people's spirit. In the formula, it assists astragalus membranaceus to tonify the essence of the human body and relieve the fatigue feeling generated during the weight loss process. Cinnamon is a hot medicine that can tonify the fire of the pericardium of the gate of vitality. Traditional Chinese medicine believes that "when the fire of the pericardium is sufficient, it can naturally stimulate the appetite to dispel phlegm; when the fire of the gate of vitality is sufficient, it can strengthen the spleen to dispel dampness." In this formula, cinnamon plays its role of dredging and making water and dampness have nowhere to gather, so that weight loss and fat reduction can be achieved naturally. Eugenia caryophyllata can warm the middle-jiao to reduce adverse qi, disperse cold and relieve pain, warm the kidney and boost yang, promote qi movement and relieve stagnation, can promote gastric juice secretion, enhance digestion, relieve nausea and vomiting, and relieve abdominal flatulence. Cannabis seed can lubricate the intestines, relieve constipation, and promote the discharge of toxins. The combined action of various herbs fundamentally metabolizes the excess water in the body, regulates the physique, and thus achieves the purpose of weight loss.

[0144] Weight loss in traditional Chinese medicine is not a simple "calorie addition and subtraction", but a systematic project of coordinating the zang-fu organs and balancing qi and blood. Therefore, the goal of the present invention is that the weight loss speed should not be fast, nor should it be fast, but should be carried out slowly under control. This goal aims to achieve gradual changes in the body and figure, ensuring a steady reduction in weight. In this way, obese friends can not only effectively lose weight, but also synchronously obtain high-quality health.

[0145] Examples, comparative examples

[0146] The preparation method of the functional medicine and food homologous product granule for weight loss, body shaping, dampness reduction and body building of the present invention includes the following steps:

[0147] 1. Weigh the medicinal materials according to the above weight ratio and wash them clean.

[0148] 2. Dry the medicinal materials and grind them into powder.

[0149] 3. After fully mixing the medicinal material powder, conduct high-temperature sterilization.

[0150] 4. Add excipients, form and granulate to form fine particles.

[0151] 5. Conduct high-temperature sterilization again to obtain the product.

[0152] The preparation method of the functional medicine-food-homologous product paste for weight loss, body shaping, moisture reduction and body building of the present invention includes the following steps:

[0153] 1. Weigh the medicinal materials according to the above weight ratio, wash them clean, decoct them strongly to remove residues, and obtain the concentrated juice.

[0154] 2. Add 200 to 500 parts of fructooligosaccharide, melt and collect the paste to obtain the product.

[0155] Example 1

[0156] A kind of functional medicine-food-homologous product granule for weight loss, body shaping, moisture reduction and body building, the raw materials thereof are as follows:

[0157] 1 part of dried tangerine peel, 3 parts of astragalus membranaceus, 1 part of lotus leaf, 1 part of agastache rugosa, 1 part of fennel, 2 parts of cornel, 1 part of ginger, 0.5 part of cinnamon, 0.5 part of clove, 2 parts of cannabis seed.

[0158] The specific preparation method is as follows:

[0159] 1. Weigh the medicinal materials according to the above weight ratio and wash them clean.

[0160] 2. Dry the medicinal materials and grind them into powder.

[0161] 3. After fully mixing the medicinal material powder, conduct high-temperature sterilization at a temperature above 100 °C.

[0162] 4. Add excipients, form and granulate to form fine particles.

[0163] 5. Conduct high-temperature sterilization at a temperature above 100 °C again to obtain the product.

[0164] Example 2

[0165] A kind of functional medicine-food-homologous product granule for weight loss, body shaping, moisture reduction and body building, the raw materials thereof are as follows:

[0166] 9 parts of dried tangerine peel, 30 parts of astragalus membranaceus, 9 parts of lotus leaf, 10 parts of agastache rugosa, 6 parts of fennel, 9 parts of cornel, 6 parts of ginger, 4 parts of cinnamon, 3 parts of clove, 12 parts of cannabis seed.

[0167] The specific preparation method is as follows:

[0168] 1. Weigh the medicinal materials according to the above weight ratio, and wash them clean.

[0169] 2. Dry the medicinal materials and grind them into powder.

[0170] 3. After fully mixing the medicinal material powder, conduct high-temperature sterilization at a temperature above 100 °C.

[0171] 4. Add excipients, form and granulate to form fine particles.

[0172] 5. Conduct high-temperature sterilization again at a temperature above 100 °C to obtain the product.

[0173] Example 3

[0174] A granule of a functional medicine-food homologous product for weight loss, body shaping, dehumidification and body building, and its raw materials are as follows:

[0175] 25 parts of dried tangerine peel, 70 parts of astragalus membranaceus, 30 parts of lotus leaf, 30 parts of agastache rugosa, 15 parts of fennel, 30 parts of cornel, 18 parts of ginger, 10 parts of cinnamon, 9 parts of cloves, 40 parts of hemp seeds.

[0176] The specific preparation method is as follows:

[0177] 1. Weigh the medicinal materials according to the above weight ratio, and wash them clean.

[0178] 2. Dry the medicinal materials and grind them into powder.

[0179] 3. After fully mixing the medicinal material powder, conduct high-temperature sterilization at a temperature above 100 °C.

[0180] 4. Add excipients, form and granulate to form fine particles.

[0181] 5. Conduct high-temperature sterilization again at a temperature above 100 °C to obtain the product.

[0182] Example 4

[0183] An ointment of a functional medicine-food homologous product for weight loss, body shaping, dehumidification and body building, and its raw materials are as follows:

[0184] 5 parts of dried tangerine peel, 6 parts of astragalus membranaceus, 5 parts of lotus leaf, 5 parts of agastache rugosa, 5 parts of fennel, 9 parts of cornel, 5 parts of ginger, 3 parts of cinnamon, 3 parts of cloves, 6 parts of hemp seeds.

[0185] The specific preparation method is as follows:

[0186] 1. Weigh the medicinal materials according to the above weight ratio, wash them clean, then decoct them strongly to remove the residue, and obtain the concentrated juice.

[0187] 2. Add 200 parts of fructooligosaccharide, melt and collect the extract to obtain the product.

[0188] Example 5

[0189] A functional medicinal and edible homologous product paste for weight loss, body shaping, moisture reduction and body building, with the following raw materials:

[0190] 135 parts of dried tangerine peel, 450 parts of astragalus membranaceus, 135 parts of lotus leaf, 150 parts of pogostemon cablin, 90 parts of fennel, 135 parts of cornel, 90 parts of ginger, 60 parts of cinnamon, 45 parts of clove, 180 parts of cannabis seed.

[0191] The specific preparation method is as follows:

[0192] 1. Weigh the medicinal materials according to the above weight ratio, wash them clean, add 8 times the amount of water, decoct for 1 hour, remove the residue, and obtain the concentrated juice.

[0193] 2. Add 300 parts of fructooligosaccharide, melt and collect the extract to obtain the product.

[0194] Example 6

[0195] A functional medicinal and edible homologous product paste for weight loss, body shaping, moisture reduction and body building, with the following raw materials:

[0196] 375 parts of dried tangerine peel, 1000 parts of astragalus membranaceus, 450 parts of lotus leaf, 450 parts of pogostemon cablin, 225 parts of fennel, 450 parts of cornel, 300 parts of ginger, 150 parts of cinnamon, 135 parts of clove, 600 parts of cannabis seed.

[0197] The specific preparation method is as follows:

[0198] 1. Weigh the medicinal materials according to the above weight ratio, wash them clean, add 8 times the amount of water, decoct for 1 hour, remove the residue, and obtain the concentrated juice.

[0199] 2. Add 500 parts of fructooligosaccharide, melt and collect the extract to obtain the product.

[0200] Comparative Example 1

[0201] This comparative example is based on Example 1, using two less medicinal materials, dried tangerine peel and astragalus membranaceus, and its preparation method is the same as that of Example 1.

[0202] Comparative Example 2

[0203] This comparative example is based on Example 1, using two less medicinal materials, lotus leaf and pogostemon cablin, and its preparation method is the same as that of Example 1.

[0204] Comparative Example 3

[0205] This comparative example is based on Example 1, using two less medicinal materials, fennel and cornel, and its preparation method is the same as that of Example 1.

[0206] Comparative Example 4

[0207] This comparative example is based on Example 4, using two less drugs, namely ginger and cinnamon, and its preparation method is the same as that of Example 4.

[0208] Comparative Example 5

[0209] This comparative example is based on Example 4, using three less drugs, namely cloves, cannabis seeds, and dried tangerine peel, and its preparation method is the same as that of Example 4.

[0210] Comparative Example 6

[0211] This comparative example is based on Example 4, using four less drugs, namely lotus leaf, agastache, fennel, and cornel, and its preparation method is the same as that of Example 4.

[0212] The effect test of the present invention is as follows:

[0213] 360 testers diagnosed with simple obesity were randomly divided into 12 groups, with 30 people in each group. 6 of the groups were respectively given the compositions prepared in Examples 1 - 6 of the present invention; the other 6 groups were given the compositions prepared in Comparative Examples 1 - 6 of the present invention. Each group was orally administered 2 times a day, 15 grams of the paste or granules each time. It was taken continuously for 8 weeks. Each group of patients was not required to deliberately diet during the treatment, but it was advisable to have a light, reasonable, and regular diet, and control the intake of high-fat foods. Three meals a day were essential, and each meal was maintained at 70 - 80% full, with a balanced diet nutrition, and moderate aerobic exercise such as walking, jogging, yoga, etc.

[0214] Diagnostic criteria: Refer to the "Diagnosis and Efficacy Evaluation Criteria for Simple Obesity" revised at the 5th National Obesity Research Academic Conference in 1997.

[0215] (1) The measured weight exceeds the standard weight by more than 20%, that is, the obesity degree ≥ 20%;

[0216] Calculation of the standard weight for adults: [height (cm) - 100] × 0.9 = standard weight (kg)

[0217] Obesity degree = (measured weight - standard weight) / standard weight × 100%

[0218] (2) Body Mass Index (BMI): Calculation of Body Mass Index (BMI): Body Mass Index (BMI) = weight (kg) / [height (m)] 2

[0219] Classification <![CDATA[Body Mass Index (kg / m 2 )]]> Comorbidity risk Normal range 18.5-23.9 Average level Overweight 24.0-27.9 Increase Obesity ≥28 Severe increase

[0220] Table 1 Diagnostic Criteria for Obesity

[0221] (3) The fat percentage (F%) is over 25% for men and over 30% for women.

[0222] Calculation of the fat percentage (F%): F% = (4.570 / D - 4.142) × 100%

[0223] The calculation of D (body density) is shown in Table 2 below:

[0224] Age Male Female 9-11 1.0879-0.00151·X 1.0794-0.00142·X 12-14 1.0868-0.00133·X 1.0888-0.00153·X 15-18 1.0977-0.00146·X 1.0931-0.00160·X ≥19 1.0913-0.00116·X 1.0897-0.00133·X

[0225] Table 2 Method for calculating D (body density)

[0226] Note: X = Subscapular skin fold thickness (mm) + Triceps skin fold thickness (mm), take the right side.

[0227] (4) Medical history, physical examination and laboratory tests can rule out symptomatic obesity (secondary obesity).

[0228] Inclusion criteria:

[0229] ① Meet the diagnostic criteria for simple obesity;

[0230] ② No other weight loss methods were used in the month before treatment and during treatment;

[0231] ③ Aged between 18 and 60 years old;

[0232] ④ Medical history, physical examination and laboratory tests can rule out symptomatic obesity (secondary obesity);

[0233] ⑤ Measured body weight and body mass index: The measured body mass index exceeds 20% of the standard body weight, and the body mass index exceeds 26;

[0234] Exclusion criteria:

[0235] ① Those who do not meet the inclusion criteria;

[0236] ② Pregnant or lactating women;

[0237] ③ Secondary obesity caused by other reasons: diseases such as hypothalamic, pituitary diseases, hypothyroidism, hypercortisolism, hyperinsulinism, gonadal secretion changes, water retention obesity, genetic obesity syndrome and drug-induced obesity;

[0238] ④ Those with combined critical illnesses such as hypertension, type II diabetes, coronary heart disease and certain cancers;

[0239] ⑤ Those with primary diseases of the cardiovascular, liver, kidney, digestive and hematopoietic systems, and psychiatric patients;

[0240] ⑥ Patients who are lost to follow-up for various reasons during treatment or follow-up, and patients who withdraw voluntarily for other reasons.

[0241] Efficacy evaluation criteria: According to the obesity efficacy evaluation criteria formulated by the International Federation of Chinese and Western Medicine in 1992:

[0242] Marked effect: Body weight reduction > 5 kg or average abdominal circumference reduction > 10 cm;

[0243] Effective: Body weight reduction 2 - 5 kg or average abdominal circumference reduction 3 - 10 cm;

[0244] Ineffective: Body weight reduction < 2 kg or average abdominal circumference reduction < 3 cm.

[0245] Blood lipid evaluation criteria: According to the criteria formulated in the "Guiding Principles for Clinical Research of Blood Lipid - regulating Drugs" by the Ministry of Health (see Table 3).

[0246] TC TG HDL-C Marked effect Decrease ≥ 20% Decrease ≥ 40% Increase ≥ 0.26 mmol / l Effective Decrease 10% - 20% Decrease 20% - 40% Increase 0.104 - 0.26 mmol / l Ineffective Increase ≥ 10% Increase ≥ 10% Decrease ≥ 0.104 mmol / l

[0247] Table 3 Blood lipid treatment evaluation criteria

[0248] Statistical method: The research data were statistically processed using the SPSS 10.0 statistical software package. All indicators in the experiment were expressed using , and when P < 0.05, it indicated that the data had statistical significance.

[0249] Treatment effect:

[0250] Comparison of clinical efficacy of 12 groups

[0251] Group Number of people Marked effect Effective Ineffective Total effective rate Example group 1 30 3 19 8 73.33％ Example group 2 30 8 20 2 93.33％ Example group 3 30 4 23 3 90％ Example group 4 30 4 21 5 83.33％ Example group 5 30 11 18 1 96.67％ Example group 6 30 5 22 3 90％ Control group 1 30 0 13 17 43.33％ Control group 2 30 1 16 13 56.67％ Control group 3 30 1 12 17 43.33％ Control group 4 30 0 15 15 50％ Control group 5 30 0 11 19 36.67％ Control group 6 30 0 9 21 30％ P - - - - <0.05

[0252] Table 4 Comparison of the efficacy of 12 groups of cases after 8 - week treatment

[0253] After 8 - week treatment, according to the indicators of body weight and average abdominal circumference, the treatment effective rate of the compositions prepared in Examples 1 - 6 for simple obesity was significantly higher than that of the compositions prepared in Comparative Examples 1 - 6 (P < 0.05). From the results of Examples 1 - 6, it can be seen that the number of cases with marked effect and effective cases in the paste - formula group was slightly more than that in the granule group.

[0254] Comparison of blood lipid change efficacy

[0255] Group Number of people Marked effect Effective Ineffective Total effective rate Example group 1 30 6 14 10 66.67％ Example group 2 30 11 17 2 93.33％ Example group 3 30 8 13 9 70％ Example group 4 30 6 14 10 66.67％ Example group 5 30 14 15 1 96.67 Example group 6 30 9 14 7 76.67％ Control group 1 30 0 10 20 33.33％ Control group 2 30 0 13 17 43.33％ Control group 3 30 0 12 18 40％ Control group 4 30 0 13 17 43.33％ Control group 5 30 0 8 22 26.67％ Control group 6 30 0 6 24 20％ P - - - - <0.01

[0256] Table 5 Comparison of blood lipid efficacy of 12 groups of cases after 8 - week treatment

[0257] From the data in Table 5, it can be seen that the total effective rate of blood lipid of the compositions prepared in Examples 1 - 6 was significantly higher than that of the compositions prepared in Comparative Examples 1 - 6 (P < 0.01). From the results of Examples 1 - 6, it can be seen that the number of cases with marked effect and effective cases in the paste - formula group was slightly more than that in the granule group.

[0258] In Comparative Example 1, since two herbs, dried tangerine peel and astragalus root, were used less, although the changes in body weight and blood lipid tended to improve compared with those before treatment, the effect was not as good as that of Example 1. It can be seen that when these two herbs, dried tangerine peel and astragalus root, are used together with the other eight herbs, they can produce a synergistic effect, thus achieving the effect of weight loss.

[0259] In Comparative Example 2, since two herbs, lotus leaf and pogostemon herb, were used less, although the changes in body weight and blood lipid tended to improve compared with those before treatment, the effect was not as good as that of Example 2. It can be seen that when these two herbs, lotus leaf and pogostemon herb, are used together with the other eight herbs, they can produce a synergistic effect, thus achieving the effect of weight loss.

[0260] In Comparative Example 3, since two herbs, fennel fruit and medicinal cornel, were used less, although the changes in body weight and blood lipid tended to improve compared with those before treatment, the effect was not as good as that of Example 3. It can be seen that when these two herbs, fennel fruit and medicinal cornel, are used together with the other eight herbs, they can produce a synergistic effect, thus achieving the effect of weight loss.

[0261] In Comparative Example 4, since two herbs, ginger and cassia bark, were used less, although the changes in body weight and blood lipid tended to improve compared with those before treatment, the effect was not as good as that of Example 4. It can be seen that when these two herbs, ginger and cassia bark, are used together with the other eight herbs, they can produce a synergistic effect, thus achieving the effect of weight loss.

[0262] In Comparative Example 5, since three herbs, clove, hemp seed, and dried tangerine peel, were used less, although the changes in body weight and blood lipid tended to improve compared with those before treatment, the effect was not as good as that of Example 5. It can be seen that when these three herbs, clove, hemp seed, and dried tangerine peel, are used together with the other seven herbs, they can produce a synergistic effect, thus achieving the effect of weight loss.

[0263] In Comparative Example 6, since four herbs, lotus leaf, pogostemon herb, fennel fruit, and medicinal cornel, were used less, although the changes in body weight and blood lipid tended to improve compared with those before treatment, the effect was not as good as that of Example 6. It can be seen that when these four herbs, lotus leaf, pogostemon herb, fennel fruit, and medicinal cornel, are used together with the other six herbs, they can produce a synergistic effect, thus achieving the effect of weight loss.

[0264] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications of the present invention fall within the scope of the claims of the present invention and their equivalent technologies, the present invention also intends to include these changes and modifications.

Claims

1. A functional medicine-food composition for weight loss, body shaping, dehumidification and bodybuilding, characterized in that: It is prepared from the following medicinal materials in parts by weight: 1-375 parts of dried tangerine peel, 3-1000 parts of raw astragalus, 1-450 parts of lotus leaves, 1-450 parts of patchouli, 1-225 parts of fennel, 2-450 parts of cornus officinalis, 1-300 parts of ginger, 0.5-150 parts of cinnamon, 0.5-135 parts of cloves, and 2-600 parts of hemp seeds.

2. The functional medicine-food composition for weight loss, body shaping, dehumidification and bodybuilding according to claim 1, characterized in that: The composition further comprises a pharmaceutically acceptable carrier.

3. A method for preparing a functional edible and medicinal product granule for weight loss, body shaping, dehumidification and bodybuilding, comprising the following steps: (1) Weigh the medicinal materials according to the following weight ratio and wash them clean; 1-25 parts of dried tangerine peel, 3-70 parts of raw astragalus, 1-30 parts of lotus leaf, 1-30 parts of patchouli, 1-15 parts of fennel, 2-30 parts of cornus officinalis, 1-18 parts of ginger, 0.5-10 parts of cinnamon, 0.5-9 parts of cloves, 2-40 parts of hemp seed; (2) drying the medicinal materials and grinding them into powder; (3) mixing the medicinal material powders and sterilizing them at high temperature; (4) adding excipients, forming granules, and forming granules; (5) Sterilize again at high temperature to obtain the product.

4. The method for preparing the functional medicinal and edible product paste prescription for weight loss, body shaping, dehumidification and bodybuilding according to claim 3, characterized in that: The step (1) further comprises a pharmaceutically acceptable carrier.

5. A method for preparing a functional medicinal and edible product paste for weight loss, body shaping, dehumidification and bodybuilding, comprising the following steps: (1) Weigh the medicinal materials according to the following weight ratio, wash them thoroughly, decoct them, remove the residue, and take the concentrated juice; 5-375 parts of dried tangerine peel, 6-1000 parts of raw astragalus, 5-450 parts of lotus leaf, 5-450 parts of patchouli, 5-225 parts of fennel, 9-450 parts of cornus officinalis, 5-300 parts of ginger, 3-150 parts of cinnamon, 3-135 parts of cloves, and 6-600 parts of hemp seed; (2) Add 200 to 500 parts of oligofructose and melt until it becomes a paste.

6. The method for preparing the functional medicinal and edible product paste for weight loss, body shaping, dehumidification and bodybuilding according to claim 5, characterized in that: The step (1) further comprises a pharmaceutically acceptable carrier.

7. Use of the functional medicine-food composition according to claim 1 in preparing functional products for assisting weight loss, body shaping, dehumidification and bodybuilding.