SERF atom magnetometer-based brain magnetic color response detection device and method

Abstract

The invention discloses a brain magnetic color response detection device and method based on an SERF atomic magnetometer, and belongs to the technical field of biological brain magnetic detection. The device comprises a brain magnetic measurement platform module. The brain magnetic measurement platform module comprises a magnetic shielding device, an SERF magnetometer sensor, a visual stimulation light source and a positioning helmet. A testee wears a positioning helmet provided with a sensor and lies in the magnetic shielding device, the visual stimulation light source is controlled to circularly generate light of different colors, human brain magnetic signals in the stage are collected and recorded, and brain magnetic responses of the testee to the light of different colors are obtained after processing. By combining the small and convenient SERF magnetometer, low-cost and high-precision brain magnetic signal efficient analysis is achieved, and the method has the advantages of being high in accuracy, low in invasiveness, easy and convenient to operate and the like. The technology not only provides a new research tool for brain science research, but also provides powerful support for nerve stimulation application and early diagnosis and treatment of brain diseases.

Description

Technical Field

[0001] The present invention relates to the technical field of biomagnetic brain detection, and particularly to a color blindness detection device and method based on the brain magnetic color response of a SERF atomic magnetometer. Background Art

[0002] Vision is an important sensory system for humans to perceive and understand the world. Through vision, humans can recognize the environment, interpret information, and communicate with others. The complexity of visual function is closely related to the nervous system. It has been found that approximately half of the cerebral cortex is involved in the processing and analysis of visual information. As a crucial and complex sensory system, vision has always attracted extensive attention from scientists.

[0003] However, the neurological mechanism of the most basic color stimuli in visual perception is still not fully understood. Currently, studies have explored the brain responses under color stimuli through techniques such as electroencephalogram (EEG) and magnetoencephalogram (MEG), but these techniques have certain limitations. The spatial resolution of EEG technology is relatively low, while MEG devices are usually large in volume, high in cost, and have strict environmental requirements. In addition, when detecting brain magnetic signals, the existing technology has not delved deeply enough into the feature extraction and analysis of brain magnetic signals in terms of color response. Therefore, there is an urgent need for a device and method that can efficiently and accurately detect the brain magnetic signals in terms of color response to fill the gap in this field of the existing technology and provide new research tools for brain science research. Summary of the Invention

[0004] To overcome the above problems, the present invention proposes a color blindness detection device based on the brain magnetic color response of a SERF atomic magnetometer

[0005] The first aspect of the present invention proposes a lesion detection device based on the brain magnetic color response of a SERF atomic magnetometer, including a brain magnetic measurement platform module, a control processing unit connected to the brain magnetic measurement platform module, and a system operation unit connected to the control processing unit;

[0006] The brain magnetic measurement platform module includes a magnetic shielding device for shielding the geomagnetic field and environmental noise, a SERF magnetometer sensor for receiving the raw brain magnetic signals, a stimulating visual light source for generating lights of different wavelengths, and a positioning helmet for installing and fixing the SERF magnetometer sensor; the SERF magnetometer sensor includes a SERF sensor probe and a SERF sensor controller; the positioning helmet has slots in multiple places, and the SERF sensor probe is fixed in the slots;

[0007] The stimulating visual light source includes an LED lamp group and a non-magnetic lamp shade. The LED lamp group generates lights with different central wavelengths and transmits them to the non-magnetic lamp shade through optical fibers. The non-magnetic lamp shade is arranged facing the eyes of the person to be tested;

[0008] The SERF sensor probe, positioning helmet, and non-magnetic lamp cover are arranged inside the magnetic shielding device, and the SERF sensor controller, LED lamp group, control processing unit, and system operation unit are arranged outside the magnetic shielding device;

[0009] The control processing unit is used to control the operation of the SERF sensor and light source, and perform data acquisition, processing, and storage; the system operation unit is used to implement the operation of the device.

[0010] The second aspect of the present invention proposes a method for detecting brain magnetic color response based on SERF atomic magnetometer, which includes the following steps:

[0011] Step 1: The subject lies flat in the shielding barrel, wears the positioning helmet, and installs the SERF sensor probe in the occipital lobe area, ensuring that the distance between the cerebral cortex in the occipital lobe area and at least one SERF sensor probe is less than 12 mm;

[0012] Step 2: First, keep the LED lamp group off for more than 50 seconds, then turn on the LED lamp group. The light emitted by the LED lamp group is transmitted to the non-magnetic lamp cover through the optical fiber to perform light stimulation on the visual system of the subject;

[0013] Step 3: The LED lamp group switches to different colors of light for stimulation, and the brain magnetic signals of the subject under different colors of light stimulation are collected by the SERF sensor;

[0014] Step 4: The collected brain magnetic signals are input into the control processing unit, and the method of wavelet packet transform is used to extract the brain magnetic signal characteristics in the α frequency band under different colors of light stimulation.

[0015] The beneficial effects of the present invention are as follows: Compared with the traditional magnetoencephalogram (MEG) technology, the brain magnetic color response detection device and method based on SERF atomic magnetometer proposed by the present invention, by combining the miniaturized and portable SERF magnetometer, realizes the efficient analysis of brain magnetic signals at low cost and high precision. Moreover, the SERF magnetometer sensor has a small volume, low cost, and is easy to maintain, which is conducive to wide application. By exploring the response of brain magnetic signals in the α wave frequency band to different colors of light, the present invention extracts the brain magnetic signal characteristics of the subject under different colors of light stimulation, can more accurately locate the brain activity areas related to colors, and more reliably reflect the response data of the subject's brain magnetic signals to colors. The detection means provided by the present invention has the advantages of high accuracy, low invasiveness, and simple operation. This technology not only provides a new research tool for brain science research, but also provides strong support for nerve stimulation applications, early diagnosis and treatment of brain diseases. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the measurement system in an embodiment of the present invention;

[0017] Figure 2 Structural diagram of the magnetoencephalogram measurement platform in an embodiment of the present invention;

[0018] Figure 3 Dual-channel magnetoencephalogram normalized original signal in an embodiment of the present invention;

[0019] Figure 4 Signal of the preprocessed α frequency band in an embodiment of the present invention;

[0020] Figure 5 Classification accuracy of magnetoencephalogram signals under different color stimuli for different subjects in an embodiment of the present invention.

[0021] Explanation of reference numerals: 1. Magnetic shielding device; 2. SERF sensor probe; 3. Cable; 4. SERF sensor controller; 5. LED lamp; 6. Non-magnetic lamp shade; 7. Optical fiber; 8. Positioning helmet. Specific implementation manners

[0022] The technical solution of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0023] In the description of the present invention, it should be noted that, as the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, it is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be construed as a limitation of the present invention. In addition, as the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0024] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, as the terms "installed", "connected", "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0025] Embodiment 1

[0026] Reference Figure 1, a color blindness detection device based on brain magneto-color response of SERF atomic magnetometer includes a brain magneto-measuring platform module, a control processing unit connected to the brain magneto-measuring platform module, and a system operation unit connected to the control processing unit;

[0027] The brain magnetometry measurement platform comprises: a magnetic shielding device 1 for shielding the earth's magnetic field and environmental noise, a SERF magnetometer sensor for receiving original brain magnetometry signals, a stimulating visual light source for generating light of different wavelengths, and a positioning helmet for installing and fixing the SERF magnetometer sensor;

[0028] The integrated small SERF magnetometer sensor includes a SERF sensor probe 2, a cable 3 and a SERF sensor controller 4;

[0029] The stimulating visual light source includes an LED lamp 5, a non-magnetic lampshade 6, and an optical fiber 7;

[0030] The biomagnetic signal of the human body is extremely weak. If it is not controlled, the earth's magnetic field and environmental electromagnetic waves will have a serious impact on the measurement. The magnetic shielding device shields the external magnetic field and electromagnetic noise to prevent external interference to its internal device. For some atomic magnetic technologies, such as SERF, the sensor probe needs to work in an environment close to zero magnetic field. In this embodiment, the magnetic shielding device 1 for shielding the earth's magnetic field and environmental noise is made of a high magnetic permeability material to form a cylindrical structure, which can effectively isolate external magnetic field interference and has an internal space to accommodate the person being measured.

[0031] The magnetic shielding device is made of high magnetic permeability alloy materials, such as Permalloy and silicon steel. The magnetic shielding device uses a certain thickness of multi-layer high magnetic permeability alloy plates to make a closed or semi-closed cavity. The size of the cavity must at least be able to accommodate the sensor probe and its accessories, and the person being measured. The magnetic field strength of the entire or partial area in the cavity is less than 50nT (the earth's magnetic field is 45000nT to 60000nT). The size of this area must at least cover all the measurement points.

[0032] The thickness of the high magnetic permeability alloy plate is preferably in the range of 0.1 mm to 10 mm. Using multiple layers of alloy plates to make a magnetic shielding device can achieve a better shielding effect and achieve the required shielding performance. In this embodiment, 3 to 5 layers of Permalloy are used to make a magnetic shielding device; in other embodiments, 8 to 10 layers of silicon steel alloy can be used to make a magnetic shielding device.

[0033] In this embodiment, a closed magnetic shielding device 1 is preferably made of four layers of permalloy and an outermost layer of aluminum alloy. One end of the shielding cylinder is covered with four permalloy covers in sequence on the four-layer permalloy cylinder, and an aluminum alloy cover is covered on the aluminum alloy shell.

[0034] In this embodiment, an integrated miniaturized SERF magnetometer sensor is used to receive raw magnetoencephalogram signals;

[0035] The SERF magnetometer sensor detects the change of atomic energy levels under the action of a magnetic field based on the interaction between light and atoms, so as to achieve precise magnetic field measurement. The SERF magnetometer sensor internally includes a laser light source, an optical prism, lenses, an atomic gas cell, and a photoelectric conversion module. The laser light source selects a miniaturized laser chip, and its wavelength corresponds to the selected atom. The optical prism and lenses shape the laser and control its polarization state, and then the laser is incident into the atomic gas cell. The atomic gas cell is a hermetically sealed glass container with high transparency, and a sufficient amount of a certain alkali metal is placed inside. In some instances, rubidium atoms are placed inside the atomic gas cell; in other instances, cesium atoms are placed inside the atomic gas cell. Under low pressure and appropriate heating conditions, an alkali metal atom vapor with a certain concentration is formed in the atomic gas cell. In some instances, an appropriate amount of nitrogen or inert gas is also added to the atomic gas cell to restrict the movement of the gaseous alkali metal to obtain better measurement results. According to the needs of actual engineering, in some instances, the atomic gas cell adopts a cube (elongated) shape; in other instances, the atomic gas cell adopts a cylindrical or spherical shape. The scale of the atomic gas cell is usually below 30 mm.

[0036] By setting appropriate temperature and magnetic field environments for the atomic gas cell and providing specific pump laser, the alkali metal vapor in the atomic gas cell is polarized and enters a certain quantum state, becoming a working medium that can sensitively perceive the magnetic field intensity. The probe laser passes through the atomic gas cell and interacts with the polarized alkali metal atoms, thereby carrying the quantum state information of the alkali metal atoms. The outgoing light is converted into an electrical signal by the photoelectric conversion module and transmitted to the control unit through a cable to achieve the analysis and extraction of the magnetic field.

[0037] One implementation solution is that the SERF magnetometer sensor includes a SERF sensor probe 2, a SERF sensor controller, and a cable 3. Among them, the atomic gas cell is installed in the atomic magnetic sensor probe to detect the magnetic field at its own location. A laser light source, a magnetic field generating device, a temperature control device, and a probe laser detection device are also installed in the sensor probe. The sensor controller provides the control signals required for these working devices of the sensor probe, receives and processes the output signals of the laser detection device. These input and output signals are transmitted through the sensor cable.

[0038] The positioning helmet is used to install and fix the SERF sensor probe of the above-mentioned SERF magnetometer sensor. In this embodiment, the positioning helmet is made by 3D printing technology. To adapt to the differences in the head sizes of different people and the specific positions of the occipital lobe areas, the positioning helmet has multiple slots, and multiple SERF magnetometer sensors are used for multi-channel synchronous acquisition. A plurality of the SERF sensor probes 2 are installed and fixed in the slots of the positioning helmet 8, so that at least one probe thereof is vertically close to the occipital lobe area of the person to be measured, ensuring that the sensor probes can simultaneously and accurately receive the magnetoencephalogram signals from the occipital lobe area; the SERF sensor probe 2 is connected to the SERF sensor controller 4 installed outside the magnetic shielding device 1 through the sensor cable 3. This layout enables the SERF sensor probe 2 to be close to the human brain to receive the magnetoencephalogram signals more closely; at the same time, the SERF sensor controller 4 is placed at a suitable distance from the SERF sensor probe 2, which can reduce magnetic field interference and ensure the accuracy and reliability of magnetoencephalogram signal detection.

[0039] The visual stimulation light source is used to generate lights of different wavelengths, and it includes an LED lamp 5, a non-magnetic lamp cover 6 and an optical fiber 7; the LED lamp 5 is a narrow-band patch lamp group, which is arranged outside the magnetic shielding device 1. The system operation unit controls the communication of the control processing unit, and outputs a trigger signal at every fixed time interval. After receiving the trigger signal, the single-chip microcomputer switches the color of the LED lamp 5. By adjusting the time interval and cycle duration of the digital output, it is possible to control the narrow-band LED lamps 5 with different central wavelengths in the lamp group to emit light for the same time; since lights of different colors have different degrees of sensitivity to the human eye vision, lights with the same light brightness but different frequencies have different stimulations to the human eye. The spectral luminous efficiency function is used to relate the light-sensitive characteristics of the human eye to the light brightness, so that the actual light power felt by the human is as consistent as possible. The light beam generated by the LED lamp 5 is transmitted to the non-magnetic lamp cover 6 in front of the human eye through the optical fiber 7 and projected onto the screen.

[0040] The non-magnetic lamp shade 6 includes three parts. The first part is a hemispherical cover made of polyvinyl chloride plastic material, with a reflective coating inside, covering the LED lamp 5. The second part is a cylindrical structure of a polyvinyl chloride plastic shell, with optical fibers installed inside. When the optical fibers transmit light, the loss is small and the transmission efficiency is high. The third part is flat, made of sulfuric acid paper material, and has the function of scattering and diffusing light. It can scatter the light beam transmitted by the optical fiber, making the light present a uniformly distributed light spot, effectively reducing the harm of the direct light source to the eyes. The three parts are connected in sequence and are all made of non-magnetic materials. The non-magnetic lamp shade 6 can also reduce the influence of external magnetic fields and external light sources on the test. Preferably, the purpose of setting the non-magnetic lamp shade 6 is as follows: 1. Uniform light spot distribution: The main purpose of the non-magnetic lamp shade is to ensure that the light beam transmitted by the LED light source through the optical fiber can be evenly distributed on the screen. Since the light source is a narrow-band LED lamp group and the light beam emitted by it may be relatively concentrated, it is easy to form uneven light spots. The non-magnetic lamp shade can scatter and evenly distribute the light beam from the optical fiber, ensuring that the light spots on the screen present a uniform brightness distribution, thereby improving the accuracy and repeatability of visual tests. 2. Prevent the direct light source from harming the eyes: After the LED light source is transmitted through the optical fiber, its light beam may directly irradiate the eyes of the subject without proper adjustment, which will cause discomfort to the eyes and may even cause temporary blurred vision or eye fatigue. The non-magnetic lamp shade can effectively prevent the strong light introduced by the optical fiber from directly irradiating the eyes, thus protecting the eyesight of the subject and improving the comfort of the test. 3. Provide the diffusion and softening effect of the light source: In addition to evenly distributing the light spots, the design of the lamp shade can also achieve the diffusion and softening of the light source. Through a reasonably designed optical structure, the lamp shade can soften the light beam from the LED light source, avoiding strong contrasts or dazzling phenomena caused by high-brightness light beams, and thus reducing visual fatigue or discomfort caused by overly strong light. 4. Isolate the magnetic field and avoid interfering with the optical system: Since the device contains electronic components and LED light sources, it will interfere with the normal operation of the magnetometer system. The non-magnetic lamp shade can play a role in isolating the magnetic field, avoiding the introduction of external magnetic fields to interfere with the magnetometer system, thereby ensuring the stable operation of the system and the reliability of the test results. 5. Improve the test accuracy and controllability: By setting the non-magnetic lamp shade, the influence of external light sources on the test can be reduced (such as the interference of ambient light). Control the propagation direction and intensity of the light source, reduce the errors caused by environmental changes, and thus improve the accuracy and controllability during the test. 6. Optimization of optical design and human-computer comfort: The design of the lamp shade also takes into account ergonomics, enabling the subject to conduct visual tests in a comfortable and interference-free environment. The non-magnetic lamp shade not only provides optical protection but also ensures the comfort of the subject during the visual test, reducing physical discomfort or anxiety caused by light discomfort, so that the subject can participate in the test more concentratedly.

[0041] The system control and data processing unit includes several modules such as sensor control, light source switch control, data acquisition, and data processing, as well as auxiliary devices such as power supply, and is set outside the magnetic shielding device 1. Among them, the functions of the sensor control, light source switch control, data acquisition, and data processing modules are implemented by computer programs.

[0042] The system operation unit consists of intelligent electronic devices such as computers or tablet computers and programs, and is connected to the system control and data processing unit through a high-speed data channel. It supports multiple system operation units to operate the system simultaneously.

[0043] Preferably, the data processing unit preprocesses the original magnetoencephalogram signals, extracts the signals in the α frequency band by using the method of wavelet packet transform; segments the magnetoencephalogram signals obtained from different color stimulations, and extracts features based on the energy domain, frequency domain, time domain, and non-linear dynamics domain. The present invention selects spectral entropy, entropy, Hjorth mobility, Hjorth complexity, variance, root mean square, absolute value mean, average frequency, maximum power spectral density, variance of average power spectral density, average power spectral density, skewness, standard fourth power deviation, power, and energy as feature indicators. The specific calculation content of the α frequency band characteristic values is as follows:

[0044]

[0045]

[0046] Reference Figure 2 , the operation steps of the magnetoencephalogram color response detection method based on SERF atomic magnetometer are as follows:

[0047] Step 1: The subject lies flat in the magnetic shielding device 1, wears the positioning helmet 8, and installs the SERF sensor probe 2 in the occipital lobe area of the posterior brain. At this time, the cerebral cortex in the occipital lobe area is 10 mm away from the detection center area. The subject maintains a quiet state in a lightless environment and adapts to the dark environment. All the subjects in this test are normal color-recognizing people without color blindness or color weakness.

[0048] Step 2: The subject receives light stimulation. There is a screen directly in front of the subject's eyes. The stimulating light source is generated by the LED lamp 5 outside the magnetic shielding device 1 and is projected onto the screen after being expanded by the fiber optic 7 and the non-magnetic lamp shade 6. The intensity of the outgoing light is about 500 μw.

[0049] Step 3: Generate different color light stimulations for 10 seconds. There is a lightless process of 60 seconds before each light stimulation to restore the subject to the quiet state of adapting to the dark environment. Then change the color and repeat this process.

[0050] Step 4: After the subject completes two color cycles and leaves the magnetic shielding device 1, the subject enters the next measurement cycle after sufficient rest, and multiple measurement cycles are repeated, so as to provide richer data for subsequent machine learning.

[0051] Step 5: The collected magnetoencephalogram signals are input into the control and processing unit for analysis to extract the magnetoencephalogram signal features in the α frequency band.

[0052] Reference Figure 3 ,4, According to the embodiment of the present invention, the magnetoencephalogram signals under different color stimuli are detected by a SERF atomic magnetometer. The part before 10 seconds is the lightless part, and the part after 10 seconds is the lighted part. When the data is not preprocessed, the difference is hardly reflected. After the extraction of the α frequency band signals, the process of light stimulation (the position of the red dotted line) can be faintly distinguished.

[0053] Embodiment 2

[0054] The present invention not only provides a new research tool for brain science research, but also provides strong support for nerve stimulation applications, early diagnosis and treatment of brain diseases. The application of the present invention in color blindness detection is described in this embodiment. After obtaining the magnetoencephalogram signal features of the subject by using the above-mentioned magnetoencephalogram color response detection method, the features of the multi-channel signals are input into a machine learning model for training. With the support of a large amount of sample data, a high classification accuracy can be achieved. The present invention provides a brand-new and objective detection method for detecting color blindness. At present, the methods for detecting color blindness mostly rely on the subjective judgment of patients. Affected by factors such as the subject's attention, visual fatigue, and environmental pressure in different test environments, the true color perception ability of the subject cannot be objectively reflected. When detecting color blindness patients with a magnetometer, the response of the α frequency band of the magnetoencephalogram signal to different color lights will show significant abnormalities, that is, differences in eigenvalue manifestations. For example, color blindness patients may have a weakened or abnormally enhanced response to certain color lights, or even present different eigenvalues. These abnormal features can be identified by a machine learning model, so as to effectively detect the presence of color blindness from a non-subjective perspective.

[0055] Preferably, the machine learning method adopted in the embodiment of the present invention is the XGBoost classification algorithm based on the Newton-Raphson optimization algorithm proposed by R. Soumya in 2024. This XGBoost classification algorithm combined with the Newton-Raphson optimization algorithm has shown significant advantages in the process of dealing with hyperparameter adjustment and model optimization.

[0056] Reference Figure 5, the extracted eigenvalue is subjected to ten-fold cross-validation. After shuffling the sample set, 1 / 10 of the samples are divided as the test set, and the rest are used as the training set. After training the training set in the machine learning model, the classification results show a relatively high classification accuracy, which indicates that the magnetoencephalogram signal features extracted by the present invention have high reliability and effectiveness and can accurately reflect the response differences of the brain to different color light stimuli. By combining a miniaturized and portable SERF magnetometer and machine learning algorithms, the present invention realizes the efficient analysis of magnetoencephalogram signals at low cost and high precision. By exploring the responses of magnetoencephalogram signals in the α-wave frequency band to different colors of light, the present invention is applied to color blindness detection and has the advantages of high accuracy, low invasiveness, and simple operation.

[0057] The content described in the embodiments of this specification is only an enumeration of the implementation forms of the inventive concept. The protection scope of the present invention should not be regarded as limited to the specific forms stated in the embodiments. The protection scope of the present invention also extends to equivalent technical means that can be conceived by those skilled in the art according to the inventive concept.

Claims

1. A brain magnetic color response detection device based on SERF atomic magnetometer, characterized in that The device includes a magnetoencephalography measurement platform module, a control and processing unit connected to the magnetoencephalography measurement platform module, and a system operation unit connected to the control and processing unit; The magnetoencephalography measurement platform module includes a magnetic shielding device for shielding the geomagnetic field and environmental noise, a SERF magnetometer sensor for receiving magnetoencephalography raw signals, a stimulation visual light source for generating lights of different wavelengths, and a positioning helmet for installing and fixing the SERF magnetometer sensor; the SERF magnetometer sensor includes a SERF sensor probe and a SERF sensor controller; the positioning helmet is provided with slots for fixing the SERF sensor probe at multiple positions, so that at least one probe in the slot is vertically close to the occipital lobe area of the subject when the subject wears the positioning helmet; The stimulation visual light source includes an LED lamp group and a non-magnetic lamp cover, the LED lamp group generates lights of different central wavelengths and transmits them to the non-magnetic lamp cover through optical fibers, and the non-magnetic lamp cover is arranged facing the eyes of the subject; The SERF sensor probe, the positioning helmet and the non-magnetic lamp cover are arranged inside the magnetic shielding device, and the SERF sensor controller, the LED lamp group, the control and processing unit and the system operation unit are arranged outside the magnetic shielding device; The control and processing unit is used to control the operation of the SERF sensor and the light source, and perform data acquisition, processing and storage; the system operation unit is used to realize the operation of the device.

2. The brain magnetic color response detection device based on SERF atomic magnetometer according to claim 1, wherein The LED lamp group is a narrow-band patch lamp group, including a plurality of narrow-band patch LED light sources.

3. The brain magnetic color response detection device based on SERF atomic magnetometer according to claim 1, characterized in that The control and processing unit includes a sensor control module, a light source switch control module, a data acquisition module and a data processing module. The sensor control module is used to control the switch of the SERF magnetometer sensor, the light source switch control module is used to control the switch of the LED lamp group, the data acquisition module is used to acquire the magnetoencephalography raw signals obtained by the SERF magnetometer sensor, and the data processing module is used to extract the magnetoencephalography features in the α frequency band from the magnetoencephalography raw signals.

4. The brain magnetic color response detection device based on the SERF atomic magnetometer according to claim 1, characterized in that, The data processing unit uses the wavelet packet transform method to perform time-frequency analysis on the magnetoencephalography signal, and further extracts the magnetoencephalography features in the α frequency band.

5. The brain magnetic color response detection device based on SERF atomic magnetometer according to claim 1, wherein The system operation unit uses a computer, a tablet computer or other intelligent devices as a control platform to realize data transmission and control with the control and processing unit.

6. A method for detecting brain magnetic color response based on SERF atomic magnetometer, characterized in that, Including the following steps: Step 1: The subject lies flat in the shielding barrel, wears the positioning helmet, installs the SERF sensor probe in the occipital lobe area, and ensures that the distance between the cerebral cortex in the occipital lobe area and at least one SERF sensor probe is less than 12 mm; Step 2: First, keep the LED lamp group turned off for more than 50 seconds, then turn on the LED lamp group. The light emitted by the LED lamp group is transmitted to the non-magnetic lamp cover through optical fibers to perform light stimulation on the visual system of the subject; Step 3: The LED lamp group switches to lights of different colors for stimulation, and the magnetoencephalography signals of the subject under the stimulation of lights of different colors are collected through the SERF sensor; Step 4: The collected magnetoencephalography signals are input into the control and processing unit and the magnetoencephalography signal features in the α frequency band under the stimulation of lights of different colors are extracted by using the wavelet packet transform method.

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