A fully automatic dry biochemical analyzer and a production process thereof

Abstract

The application belongs to the technical field of biochemical analyzers, and provides a full-automatic dry biochemical analyzer and a production process thereof, which comprise a rack device, a constant temperature control device, an optical path module, a detection and analysis assembly, a mechanical transmission system and a control module; the constant temperature control device is used for implementing constant temperature control, and the optical path module is used for providing a light source required for detection and analysis; the detection and analysis assembly is used for performing biochemical analysis on a target specimen; the mechanical transmission system is used for driving and controlling the work of the detection and analysis assembly; and the control module is used for managing and controlling the constant temperature control device, the optical path module and the mechanical transmission system based on data acquisition of the constant temperature control device and the optical path module. The application can improve the reliability of analysis results, ensure the accuracy of detection signals, quickly and accurately complete biochemical analysis on the target specimen, and improve the overall performance of the analyzer.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of biochemical analyzers, and particularly relates to a full-automatic dry biochemical analyzer and a production process thereof. BACKGROUND

[0002] The biochemical analyzer is used for detecting various biochemical indexes in blood and body fluid samples, such as blood sugar and liver function indexes; the temperature control equipment of the traditional biochemical analyzer adopts Peltier element temperature control, and has the defects of poor temperature uniformity and easy aging of the heating sheet; poor temperature uniformity greatly affects the final test precision of the equipment.

[0003] The light source of the traditional biochemical analyzer is a halogen lamp, which has a relatively short service life, a relatively large light decay, a large amount of heat and concentrated heat, and needs a radiator and a fan to solve the heat dissipation problem; the light source has a large source of late-stage decay, unstable heat dissipation, and affects the final test precision of the product; in addition, due to the short service life of the light source, the light source needs to be replaced in the later use process, which increases the consumable cost, labor cost and efficiency;

[0004] The light path structure of the traditional biochemical analyzer adopts a multi-channel beam splitter, and the light is divided by each channel beam splitter; the cumulative loss of the light is great after the light passes through the light path and the light part; due to the great loss of the light intensity of the last channel, it cannot meet the demand of more light wave testing; currently, there are at most eight different light waves; due to the relatively small number of light waves, the test precision of the product is ultimately affected;

[0005] The mechanical transmission system of the traditional biochemical analyzer has many components and a complex structure, and it is difficult to maintain; and the manufacturing process of the key components is complex;

[0006] The manufacturing process of the traditional biochemical analyzer has a low degree of modularity, which leads to low assembly efficiency, complex calibration process, and long test period.

[0007] Therefore, it is necessary to provide a full-automatic dry biochemical analyzer and a production process thereof. SUMMARY

[0008] The present application provides a full-automatic dry biochemical analyzer and a production process thereof, which can improve the reliability of the analysis result, ensure the accuracy of the detection signal, quickly and accurately complete the biochemical analysis of the target sample, and improve the overall performance of the analyzer.

[0009] The application provides a full-automatic dry biochemical analyzer, comprising: a rack device, a constant temperature control device, an optical path module, a detection and analysis assembly, a mechanical transmission system and a control module; the constant temperature control device is used for implementing constant temperature control, and the optical path module is used for providing a light source required for detection and analysis; the detection and analysis assembly is used for performing biochemical analysis on a target specimen; the mechanical transmission system is used for driving and controlling the work of the detection and analysis assembly; and the control module is used for managing and controlling the constant temperature control device, the optical path module and the mechanical transmission system based on data collection on the constant temperature control device and the optical path module.

[0010] Further, the rack device comprises a base and an integrated support, and a plurality of silica gel shock pads are arranged on the four corners of the base.

[0011] Further, the constant temperature control device comprises a temperature control unit, a heating element and a temperature sensor; the temperature control unit comprises a temperature control circuit and a circulating fan; the temperature control circuit is used for heating the heating element to increase the internal air temperature of the full-automatic dry biochemical analyzer; the circulating fan is used for making the internal air of the full-automatic dry biochemical analyzer flow; and the temperature sensor is used for collecting the internal air temperature of the full-automatic dry biochemical analyzer in real time and feeding back the collected air temperature to the temperature control unit.

[0012] Further, the temperature control unit integrates an environmental temperature compensation algorithm, and dynamically adjusts the parameters of a PID controller according to the internal air temperature of the full-automatic dry biochemical analyzer fed back by the temperature sensor.

[0013] Further, the optical path module comprises a light source assembly and a photoelectric detector; the light source assembly comprises a light emitter and a light receiver; the light source assembly is an LED array, and the LED array adopts 12 or 16 independent LED light sources; each independent LED light source corresponds to an independent photoelectric detection channel; and the photoelectric detector is used for implementing photoelectric signal conversion on the LED light source.

[0014] Further, the optical path module further comprises an intelligent attenuation compensation unit; the intelligent attenuation compensation unit comprises:

[0015] Based on the current sensor and the light intensity detector, the driving current and the output light intensity of each LED light source are collected respectively;

[0016] According to the driving current and the output light intensity, the life of each LED light source is predicted based on an Arrhenius correction model to obtain a life prediction result of the LED light source;

[0017] According to the life prediction result of the LED light source, a multi-level alarm strategy is set;

[0018] If the life prediction value in the life prediction result of the LED light source is less than a set life threshold value, the driving current is dynamically adjusted according to a real-time light decay rate, and a temperature drift term generated is corrected.

[0019] Further, the mechanical transmission system comprises a motor and a transmission assembly; the motor is configured to provide power for the transmission assembly, and the transmission assembly is configured to drive the control detection analysis assembly to work.

[0020] Further, the control module comprises a main control chip and a data acquisition assembly; the data acquisition assembly is configured to acquire temperature data of the constant temperature control device, light source intensity data of the light path module, and position positioning data of the transmission assembly; the main control chip controls the constant temperature control device, the light path module, and the mechanical transmission system to work based on a dynamic compensation strategy according to an analysis and processing result of the temperature data, the light source intensity data, and the position positioning data.

[0021] The dynamic compensation strategy comprises temperature drift compensation, light path attenuation compensation, and mechanical error compensation; the temperature drift compensation is to adjust the rotating speed of the circulating fan when the temperature difference is greater than a set temperature threshold; the light path attenuation compensation is to real-time correct the detection signal of the photoelectric detector according to a matching relationship curve between the LED current in the photoelectric detector and the light intensity; and the mechanical error compensation is to update the control parameters of the mechanical transmission system based on the position positioning data.

[0022] Further, the control module further comprises a device health degree evaluation unit, which is configured to:

[0023] acquire device health degree evaluation parameters of the full-automatic dry biochemical analyzer; the device health degree evaluation parameters comprise a motor current ripple coefficient, a heating sheet resistance change rate, and a photoelectric detector dark current value;

[0024] acquire working environment parameters of the full-automatic dry biochemical analyzer; the working environment parameters comprise an environmental temperature and an environmental humidity;

[0025] acquire working running state data of the full-automatic dry biochemical analyzer; the working running state data comprises an accumulated running time length and a daily average detection frequency;

[0026] establish a component life degradation model based on a long short-term memory network;

[0027] based on the device health degree evaluation detection parameters, the working environment parameters, and the working running state data, the component life degradation model is used to predict the life of the full-automatic dry biochemical analyzer; if the predicted remaining life is less than a set first life threshold, a self-repair strategy is triggered to be executed; if the predicted remaining life is less than a set second life threshold, a warning is issued; the self-repair strategy comprises light path attenuation compensation and mechanical transmission system reverse gap compensation; the light path attenuation compensation comprises executing reference light path calibration; and the mechanical transmission system reverse gap compensation comprises compensation based on a set mapping table of position and compensation amount.

[0028] A production process of a full-automatic dry biochemical analyzer, comprising the following steps:

[0029] S1: install silica gel shock pad to the base, and then assemble integrated support;

[0030] S2: implement modular assembly, specifically comprising:

[0031] S201: assemble constant temperature module, install heating element and temperature sensor to the biochemical analysis detection area arranged in the integrated support, and connect with the arranged temperature control unit;

[0032] S202: assemble optical path module, install light source assembly and photodetector in the biochemical analysis detection area arranged in the integrated support, and use standard sample to calibrate optical path; optical path calibration comprises light source intensity calibration, wavelength accuracy calibration and photodetector response linearity calibration;

[0033] S203: install detection analysis assembly in the biochemical analysis detection area arranged in the integrated support; wherein the guide rail of target sample tray support in the detection analysis assembly is integrally printed and produced based on laser selective melting technology;

[0034] S204: install mechanical transmission system in the integrated support, and perform motion precision test and position positioning calibration;

[0035] S205: install control module in the integrated support, and burn control program;

[0036] S3: perform function test and performance verification on the full-automatic dry biochemical analyzer.

[0037] Compared with the prior art, the present application has the following advantages and beneficial effects: through the highly integrated module design, an efficient biochemical analysis process is realized; the modules work in cooperation to ensure the accuracy and stability of the analysis results; the intelligent temperature control system of the constant temperature control device, combined with the environmental temperature compensation algorithm, can accurately control the internal temperature of the instrument, reduce the influence of temperature fluctuations on the analysis results, and improve the accuracy and repeatability of the analysis; the optical path module adopts advanced liquid crystal adjustable filter and multi-channel LED light source design, which not only improves the stability and flexibility of the light source, but also predicts and dynamically adjusts the service life of the light source through the intelligent attenuation compensation unit, effectively prolongs the service life of the light source, and reduces the maintenance cost; the mechanical transmission system adopts high-precision motor and transmission components to ensure the accurate positioning and smooth running of the detection and analysis components; the control module integrates powerful data processing and analysis functions, can monitor and analyze various parameters of the instrument in real time, and dynamically adjusts the working state of the instrument according to the analysis results, realizing intelligent management and control. In addition, the equipment health evaluation unit can comprehensively evaluate the health status of the instrument, predict the remaining life of the instrument, and provide strong support for the maintenance and maintenance of the instrument.

[0038] Other features and advantages of the present application will be set forth in the following description, and in part will become apparent to those skilled in the art from the description, or can be learned by practice of the present application. The objects and other advantages of the present application can be achieved and obtained by the structure particularly pointed out in the written description and the accompanying drawings.

[0039] The technical solutions of the present application will be further described in detail below by means of the accompanying drawings and examples. BRIEF DESCRIPTION OF DRAWINGS

[0040] The accompanying drawings are used to provide a further understanding of the present application, and constitute a part of the specification, together with the embodiments of the present application, to explain the present application, and do not constitute a limitation on the present application. In the drawings:

[0041] Figure 1 It is a structural schematic diagram of a full-automatic dry biochemical analyzer;

[0042] Figure 2 It is a structural schematic diagram of a constant temperature control device;

[0043] Figure 3 It is a production process schematic diagram of a full-automatic dry biochemical analyzer. DETAILED DESCRIPTION

[0044] The preferred embodiments of the present application will be described below in conjunction with the accompanying drawings, and it should be understood that the preferred embodiments described herein are only used to illustrate and explain the present application, and do not limit the present application.

[0045] The present application provides a full-automatic dry biochemical analyzer, asFigure 1 As shown, comprising:

[0046] The rack device, the constant temperature control device, the optical path module, the detection analysis component, the mechanical transmission system and the control module; the constant temperature control device is used for implementing constant temperature control, the optical path module is used for providing light source required by detection analysis; the detection analysis component is used for biochemical analysis on target specimen; the mechanical transmission system is used for driving control of the work of the detection analysis component; the control module is used for management control of the constant temperature control device, the optical path module and the mechanical transmission system based on data acquisition of the constant temperature control device and the optical path module.

[0047] The working principle of the above technical solution is that: the constant temperature control device provided by the application can ensure that the temperature inside the analyzer remains stable, providing a suitable environment for biochemical analysis; the light source emitted by the optical path module is precisely adjusted to illuminate the target specimen, making the detection analysis more accurate; the detection analysis component contains high-sensitivity sensors that can capture biochemical reaction information of the specimen and convert it into analyzable data; the mechanical transmission system ensures that the detection analysis component can move and operate according to the predetermined program through precise mechanical structure; the control module as the core of the whole system receives data from the constant temperature control device and the optical path module, processes quickly and issues instructions to accurately regulate the constant temperature control device, the optical path module and the mechanical transmission system, to ensure the accuracy and reliability of biochemical analysis.

[0048] The beneficial effects of the above technical solution are: the design of the fully automatic dry biochemical analyzer provided by the embodiment not only improves the efficiency of biochemical analysis, but also reduces the error caused by human operation, providing strong support for medical research and clinical diagnosis.

[0049] In one embodiment, the rack device includes a base and an integrated support, and the base is provided with a plurality of silica gel shock pads on the four corners.

[0050] The working principle of the above technical solution is that: the design of the silica gel shock pad is to reduce the influence of external vibration on the internal precision components of the analyzer, to ensure the stability and accuracy of the biochemical analysis process; the integrated support uses high-strength lightweight materials, which not only ensures the stability of the structure, but also facilitates the overall transportation and installation; on the rack device, through the design of the sliding rail and the fixed buckle, each functional module such as the constant temperature control device, the optical path module and the detection analysis component can be conveniently and quickly installed and disassembled, facilitating daily maintenance and upgrading.

[0051] The beneficial effects of the above technical solution are: by the design of the rack device, the flexibility of the equipment is improved, and the service life of the instrument is prolonged.

[0052] In one embodiment, as shown inFigure 2 As shown, the constant temperature control device includes a temperature control unit, a heating element and a temperature sensor; the temperature control unit includes a temperature control circuit and a circulating fan; the temperature control circuit is used for heating the heating element to increase the internal air temperature of the fully automatic dry biochemical analyzer; the circulating fan is used for circulating the internal air of the fully automatic dry biochemical analyzer; the temperature sensor is used for collecting the internal air temperature of the fully automatic dry biochemical analyzer in real time, and feeding back the collected air temperature to the temperature control unit.

[0053] The working principle of the above technical solution is that: the temperature control unit adjusts the heating power of the heating element accurately through the temperature control circuit according to the temperature information fed back by the temperature sensor, so as to keep the internal temperature of the analyzer constant; the continuous operation of the circulating fan effectively promotes the uniform distribution of the internal air of the analyzer, avoiding the situation that the local temperature is too high or too low, thereby ensuring the consistency and stability of the temperature in the biochemical analysis process.

[0054] The beneficial effects of the above technical solution are: the scheme provided in this embodiment not only improves the accuracy of biochemical analysis, but also effectively reduces the influence of temperature change on the analysis result, further improving the performance of the fully automatic dry biochemical analyzer.

[0055] In one embodiment, the temperature control unit integrates an environmental temperature compensation algorithm, and dynamically adjusts the parameters of the PID controller according to the internal air temperature of the fully automatic dry biochemical analyzer fed back by the temperature sensor.

[0056] The working principle of the above technical solution is that: the environmental temperature compensation algorithm built-in the temperature control unit can intelligently identify and analyze the influence of the current environmental temperature on the internal temperature of the analyzer, when the temperature sensor feeds back the internal air temperature of the analyzer to the temperature control unit in real time, the algorithm will quickly calculate the PID controller parameter adjustment amount required to maintain the internal temperature constant, by dynamically adjusting the proportional, integral and differential coefficients of the PID controller, the temperature control unit can accurately control the heating power of the heating element, to compensate for the disturbance caused by the change of environmental temperature, and ensure that the internal temperature of the analyzer always remains in an ideal constant range.

[0057] The beneficial effects of the above technical solution are: the scheme provided in this embodiment effectively improves the flexibility and accuracy of temperature control, further enhances the adaptability and analysis accuracy of the fully automatic dry biochemical analyzer under different environmental conditions.

[0058] In one embodiment, the optical path module includes a light source assembly and a photoelectric detector; the light source assembly includes a light emitting device and a light receiving device; the light source assembly is an LED array, and the LED array adopts 12 or 16 independent LED light sources; each independent LED light source corresponds to an independent photoelectric detection channel; the photoelectric detector is used for implementing photoelectric signal conversion on the LED light source.

[0059] The working principle of the technical solution is that the LED array in the application serves as a light source assembly, which can provide stable and high-intensity light to ensure the stability and reliability of the optical signal in the biochemical analysis process. Each independent LED light source corresponds to an independent photoelectric detection channel. This design enables the analyzer to flexibly select specific LED light sources and corresponding photoelectric detection channels for different detection items or different reaction systems. When the LED light source emits light to irradiate the biochemical reaction sample, the biochemical reaction in the sample will produce specific optical signal changes. These optical signals are then captured by the corresponding photoelectric detector and converted into electrical signals. The photoelectric detector has high sensitivity and fast response characteristics, and can accurately convert the captured optical signals into electrical signals, which are then analyzed and processed by the subsequent signal processing unit to obtain accurate biochemical analysis results.

[0060] The beneficial effects of the technical solution are that the full-automatic dry biochemical analyzer can accurately detect multiple biochemical indicators by the design of the optical path module.

[0061] In one embodiment, the optical path module further includes an intelligent attenuation compensation unit; the intelligent attenuation compensation unit includes:

[0062] Based on the current sensor and the light intensity detector, the driving current and the output light intensity of each LED light source are collected respectively;

[0063] According to the driving current and the output light intensity, the life of each LED light source is predicted based on the Arrhenius correction model to obtain the life prediction result of the LED light source;

[0064] According to the life prediction result of the LED light source, a multi-level alarm strategy is set;

[0065] If the life prediction value in the life prediction result of the LED light source is less than the set life threshold, the driving current is dynamically adjusted according to the real-time light attenuation rate, and the generated temperature drift term is corrected.

[0066] The working principle of the above technical solution is that the core function of the intelligent attenuation compensation unit is to monitor and compensate the attenuation of the LED light source in real time. During the working process of the analyzer, the current sensor accurately measures the driving current of each LED light source, and the light intensity detector detects the corresponding output light intensity. These two parameters are key indicators for evaluating the state of the LED light source. After obtaining the driving current and output light intensity data, the system processes these data using the Arrhenius correction model. This model can consider factors such as the working conditions and material properties of the LED light source to accurately predict the remaining life of the LED light source. The prediction results serve as the basis for subsequent operations. Based on the life prediction results, the intelligent attenuation compensation unit sets up a multi-level alarm strategy. When it is predicted that the life of a certain LED light source will reach or has fallen below the set life threshold, the system triggers the corresponding alarm mechanism to remind the operator to take timely measures. The unit can also dynamically adjust the driving current of the LED light source according to the real-time light decay rate. Through this adjustment, the light intensity attenuation of the LED light source due to long-term operation can be effectively compensated, ensuring the stability and accuracy of the analyzer. At the same time, the system also corrects the drift term caused by temperature changes, further improving the reliability of the detection results.

[0067] The beneficial effects of the above technical solution are that the scheme provided in this embodiment can significantly prolong the service life of the LED light source, reduce detection errors caused by light source attenuation, and improve the overall performance and reliability of the fully automatic dry biochemical analyzer.

[0068] In one embodiment, the mechanical transmission system includes a motor and a transmission assembly; the motor is used to provide power for the transmission assembly, and the transmission assembly is used to drive and control the work of the detection and analysis assembly.

[0069] The working principle of the above technical solution is that after the motor is started, power is transmitted to the transmission assembly through precise speed control; the transmission assembly drives the detection and analysis assembly to perform various actions such as sample suction, distribution, mixing, and movement of the detection area according to the preset program and path; these actions work together to ensure that the sample can accurately and efficiently pass through the detection area, and the detection and analysis assembly can accurately perform the detection task.

[0070] The beneficial effects of the above technical solution are that the scheme provided in this embodiment fully considers stability and durability in the design of the entire mechanical transmission system, ensuring that high precision and high efficiency can be maintained even under long-term continuous operation.

[0071] In one embodiment, the control module comprises a master chip and a data acquisition component; the data acquisition component is used to acquire temperature data of the constant temperature control device, light source intensity data of the light path module and position positioning data of the transmission component; the master chip controls the constant temperature control device, the light path module and the mechanical transmission system to work based on the dynamic compensation strategy according to the analysis and processing results of the temperature data, the light source intensity data and the position positioning data;

[0072] The dynamic compensation strategy comprises temperature drift compensation, light path attenuation compensation and mechanical error compensation; the temperature drift compensation is to adjust the rotating speed of the circulating fan when the temperature difference is greater than the set temperature threshold; the light path attenuation compensation is to real-time correct the detection signal of the photoelectric detector according to the matching relationship curve of the LED current and the light intensity in the photoelectric detector; and the mechanical error compensation is to update the control parameters of the mechanical transmission system based on the position positioning data.

[0073] The working principle of the above technical solution is that the data acquisition component in the present application monitors the temperature of the constant temperature control device, the light source intensity of the light path module and the accurate position of the transmission component in real time; after the master chip receives these data, it will immediately perform complex analysis and processing; according to the processing result, the master chip will use the dynamic compensation strategy to finely control each component; when the temperature drifts, that is, the difference between the actual temperature and the ideal temperature exceeds the preset threshold, the master chip will instruct the circulating fan to adjust the rotating speed to quickly restore the constant temperature state; when the light source intensity in the light path module attenuates with time, the master chip will real-time correct the signal of the photoelectric detector according to the preset matching relationship curve of the LED current and the light intensity, to ensure the accuracy of detection; for the small error in the mechanical transmission system, the master chip dynamically adjusts the control parameters according to the position positioning signal to maintain the high accuracy of the mechanical transmission; this series of actions seamlessly connects together to jointly ensure that the fully automatic dry biochemical analyzer can always complete the task stably and accurately in the complex and changeable detection environment.

[0074] The above technical solution has the beneficial effects that: by using the scheme provided in the embodiment, the detection accuracy and stability of the fully automatic dry biochemical analyzer can be significantly improved; through real-time monitoring and dynamic compensation strategy, the problems of temperature drift, light source intensity attenuation and mechanical transmission error are effectively solved, and the accuracy of the detection result is ensured; the fast response and fine control ability of the master chip enable the instrument to maintain stable performance when facing complex and changeable detection environment; the automation degree of the instrument is also improved, and the demand for manual intervention is reduced, thereby improving the detection efficiency and reliability.

[0075] In one embodiment, the control module further comprises a device health degree evaluation unit, and the health degree evaluation unit is used to:

[0076] Detecting and acquiring equipment health degree evaluation parameters of the full-automatic dry biochemical analyzer; the equipment health degree evaluation parameters include motor current ripple coefficient, heating plate resistance change rate and photoelectric detector dark current value;

[0077] Detecting and acquiring working environment parameters of the full-automatic dry biochemical analyzer; the working environment parameters include environmental temperature and environmental humidity;

[0078] Detecting and acquiring working running state data of the full-automatic dry biochemical analyzer; the working running state data includes cumulative running time length and daily average detection times;

[0079] Establishing a component life degradation model based on a long short-term memory network;

[0080] Based on the equipment health degree evaluation detection parameters, the working environment parameters and the working running state data, the component life degradation model is used to predict the life of the full-automatic dry biochemical analyzer, if the predicted remaining life is less than the set first life threshold, a self-repair strategy is triggered to be executed, if the predicted remaining life is less than the set second life threshold, a warning is issued; the self-repair strategy includes optical path attenuation compensation and mechanical transmission system reverse gap compensation; the optical path attenuation compensation includes executing reference optical path calibration; the mechanical transmission system reverse gap compensation includes compensation based on the mapping table of the set position and compensation amount.

[0081] The working principle of the above technical solution is that: the control module monitors and analyzes various key indicators of the full-automatic dry biochemical analyzer in real time through the integrated equipment health degree evaluation unit; the motor current ripple coefficient reflects the stability of the motor running state, the heating plate resistance change rate reveals the aging degree of the heating system, and the photoelectric detector dark current value is directly related to the sensitivity of the optical system; the accurate acquisition of these equipment health degree evaluation parameters provides a solid foundation for subsequent life prediction; at the same time, the monitoring of environmental temperature and humidity ensures that the analyzer can operate under the best working conditions, avoiding performance degradation or failure caused by environmental factors, and the collection of working running state data such as cumulative running time length and daily average detection times provides an important basis for evaluating the use intensity and maintenance requirements of the analyzer; the component life degradation model established based on the long short-term memory network can comprehensively consider historical data and current state to realize accurate prediction of the life of each component of the analyzer; when the predicted remaining life is lower than the preset first life threshold, the control module will automatically trigger the self-repair strategy, effectively prolonging the service life of the analyzer, reducing downtime and improving overall operating efficiency through means such as optical path attenuation compensation and mechanical transmission system reverse gap compensation; if the predicted remaining life further decreases to below the second life threshold, the system will issue a warning to notify the operator to take further maintenance measures or replace key components in time to avoid potential failures and ensure the continuous and stable operation of the full-automatic dry biochemical analyzer.

[0082] The technical scheme has the beneficial effects that: the scheme provided by the embodiment can realize comprehensive health monitoring and life prediction of the full-automatic dry biochemical analyzer, significantly improves the maintenance efficiency and service life of the equipment; by monitoring key indicators such as motor current ripple coefficient, heating plate resistance change rate and photoelectric detector dark current value in real time, potential operation problems of the equipment can be found in time, accurate fault information is provided for maintenance personnel, and downtime caused by fault troubleshooting is reduced; the component life degradation model established based on the long short-term memory network can accurately predict the residual life of each component of the analyzer, and provides a scientific basis for the maintenance plan of the equipment.

[0083] A production process of a full-automatic dry biochemical analyzer, as shown in Figure 3 The production process comprises the following steps:

[0084] S1: install silica gel shock pads to the base, and then assemble an integrated support;

[0085] S2: implement modular assembly, specifically comprising:

[0086] S201: assemble the constant temperature module, install the heating element and the temperature sensor to the biochemical analysis detection area provided in the integrated support, and connect with the provided temperature control unit;

[0087] S202: assemble the optical path module, install the light source assembly and the photoelectric detector in the biochemical analysis detection area provided in the integrated support, and use a standard sample to calibrate the optical path; the optical path calibration comprises light source intensity calibration, wavelength accuracy calibration and photoelectric detector response linearity calibration;

[0088] S203: install the detection and analysis assembly in the biochemical analysis detection area configured in the integrated support; wherein the guide rail of the target sample tray support in the detection and analysis assembly is integrally printed and produced based on the laser selective melting technology;

[0089] S204: install the mechanical transmission system in the integrated support, and perform motion precision test and position positioning calibration;

[0090] S205: install the control module in the integrated support, and burn the control program;

[0091] S3: perform function test and performance verification on the full-automatic dry biochemical analyzer.

[0092] The working principle of the technical scheme is as follows: in order to realize the production process of the full-automatic dry biochemical analyzer, the instrument running vibration is effectively reduced by the silica gel damping pad, and the detection precision is improved; then the modular assembly is implemented, specifically, the temperature of the biochemical analysis detection area is accurately controlled by the heating element and the temperature sensor, and the consistency of the reaction condition is ensured; then the light path module is assembled, after strict calibration, the light source intensity is stable, the wavelength is accurate, and the photoelectric detector response linearity is good, so as to improve the detection accuracy and sensitivity; the guide rail of the target sample tray support in the detection and analysis assembly is integrally printed by the laser selective melting technology, has high precision and stability, and ensures the accurate placement and movement of the sample; the mechanical transmission system is tested and calibrated in motion precision and position positioning, ensures the accurate cooperation and movement of each part, and improves the stability and reliability of the instrument; the control module is burned with the control program, realizes the automatic control and data processing of the instrument; finally, after the function test and performance verification, it is ensured that the full-automatic dry biochemical analyzer can meet the design requirements, and accurate, fast and reliable detection results are provided for biochemical analysis.

[0093] The beneficial effects of the technical scheme are as follows: the design of the full-automatic dry biochemical analyzer provided by the embodiment not only improves the efficiency of biochemical analysis, but also reduces the error caused by human operation, and provides strong support for medical research and clinical diagnosis.

[0094] Obviously, those skilled in the art can make various modifications and variations to the present application without departing from the spirit and scope of the present application. Thus, if these modifications and variations of the present application belong to the scope of the claims of the present application and their equivalent technologies, the present application also intends to include these modifications and variations.

Claims

1. A fully automatic dry-chemistry biochemical analyzer characterized by comprising: The rack device, the constant temperature control device, the optical path module, the detection and analysis assembly, the mechanical transmission system and the control module are included; the constant temperature control device is used for implementing constant temperature control, and the optical path module is used for providing light sources required by detection and analysis; the detection and analysis assembly is used for biochemical analysis on target samples; the mechanical transmission system is used for driving and controlling the work of the detection and analysis assembly; and the control module is used for managing and controlling the constant temperature control device, the optical path module and the mechanical transmission system based on data collection of the constant temperature control device and the optical path module; The control module further includes a device health degree evaluation unit, and the health degree evaluation unit is used for: detecting and acquiring device health degree evaluation parameters of the full-automatic dry biochemical analyzer; the device health degree evaluation parameters include a motor current ripple coefficient, a heating sheet resistance change rate and a photodetector dark current value; detecting and acquiring working environment parameters of the full-automatic dry biochemical analyzer; the working environment parameters include environmental temperature and environmental humidity; detecting and acquiring working running state data of the full-automatic dry biochemical analyzer; the working running state data includes cumulative running time length and daily average detection times; a component life degradation model is established based on a long short-term memory network; based on the device health degree evaluation detection parameters, the working environment parameters and the working running state data, the component life degradation model is used for life prediction of the full-automatic dry biochemical analyzer, if the predicted remaining life is less than a set first life threshold, a self-repair strategy is triggered to be executed, if the predicted remaining life is less than a set second life threshold, a warning is issued; the self-repair strategy includes optical path attenuation compensation and mechanical transmission system reverse gap compensation; the optical path attenuation compensation includes executing reference optical path calibration; and the mechanical transmission system reverse gap compensation includes compensation based on a set mapping table of positions and compensation amounts.

2. The fully automatic dry-type biochemical analyzer according to claim 1, wherein The rack device includes a base and an integrated support, and the base is provided with a plurality of silica gel shock pads at four corners.

3. The fully automatic dry-type biochemical analyzer according to claim 1, wherein The constant temperature control device includes a temperature control unit, a heating element and a temperature sensor; the temperature control unit includes a temperature control circuit and a circulating fan; the temperature control circuit is used for heating the heating element to increase the internal air temperature of the full-automatic dry biochemical analyzer; the circulating fan is used for making the internal air of the full-automatic dry biochemical analyzer flow; and the temperature sensor is used for collecting the internal air temperature of the full-automatic dry biochemical analyzer in real time and feeding back the collected air temperature to the temperature control unit.

4. The fully automatic dry-type biochemical analyzer according to claim 3, wherein The temperature control unit integrates an environmental temperature compensation algorithm, and dynamically adjusts the parameters of the PID controller according to the internal air temperature of the full-automatic dry biochemical analyzer fed back by the temperature sensor.

5. The fully automatic dry-type biochemical analyzer according to claim 1, wherein The optical path module includes a light source assembly and a photodetector; the light source assembly includes a light emitter and a light receiver; the light source assembly is an LED array, and the LED array adopts 12 or 16 independent LED light sources; each independent LED light source corresponds to an independent photodetection channel; and the photodetector is used for implementing photoelectric signal conversion on the LED light source.

6. The fully automatic dry-type biochemical analyzer according to claim 5, wherein The optical path module further includes an intelligent attenuation compensation unit; the intelligent attenuation compensation unit includes: based on a current sensor and a light intensity detector, the driving current and the output light intensity of each LED light source are collected respectively; According to the driving current and the output light intensity, the life of each LED light source is predicted based on an Arrhenius correction model to obtain a life prediction result of the LED light source; According to the life prediction result of the LED light source, a multi-level alarm strategy is set; If the life prediction value in the life prediction result of the LED light source is less than a set life threshold, the driving current is dynamically adjusted according to a real-time light decay rate, and a generated temperature drift term is corrected.

7. The fully automatic dry-type biochemical analyzer according to claim 1, wherein The mechanical transmission system comprises a motor and a transmission assembly; the motor is used to provide power for the transmission assembly, and the transmission assembly is used to drive the work of the control detection analysis assembly.

8. The fully automatic dry biochemical analyzer according to claim 7, characterized in that, The control module comprises a main control chip and a data acquisition assembly; the data acquisition assembly is used to acquire temperature data of the constant temperature control device, light source intensity data of the light path module and position positioning data of the transmission assembly; the main control chip controls the work of the constant temperature control device, the light path module and the mechanical transmission system based on a dynamic compensation strategy according to the analysis and processing results of the temperature data, the light source intensity data and the position positioning data; The dynamic compensation strategy comprises temperature drift compensation, light path attenuation compensation and mechanical error compensation; the temperature drift compensation is to adjust the rotating speed of the circulating fan when the temperature difference is greater than a set temperature threshold; the light path attenuation compensation is to correct the detection signal of the photoelectric detector in real time according to a set matching relationship curve of the LED current and the light intensity in the photoelectric detector; and the mechanical error compensation is to update the control parameters of the mechanical transmission system based on the position positioning data.

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