Pharmacogenomics detection kit

Abstract

The invention discloses a pharmacogenomics detection kit. The kit comprises a shell, a left cover, a right cover, a tube placing structure and a bin box mechanism, the double-side independent opening and closing cover body is adopted to realize one-hand opening and closing operation, and is matched with a three-section type movement track of the liftable test tube platform: the test tube platform is kept stable during horizontal moving-out and is self-locked and fixed after being lifted, and a double-track sliding system is combined to eliminate operation shaking, so that reagent tubes are accurately and smoothly taken and placed; a semiconductor refrigeration and electric heating wire double-temperature-area module is arranged inside, refrigeration and constant-temperature environments are independently maintained, uniform distribution and physical isolation of a temperature field are achieved through the design of a circulating airflow system and a sealing division bar, and cross contamination of reagents is avoided; a three-jaw radial synchronous clamping and bottom lifting linkage mechanism is adopted to adapt to reagent tubes of different specifications, so that dual positioning protection is formed, and tube body inclination, breakage or solution leakage caused by transportation jolt is effectively prevented; the detection efficiency and the reagent safety are remarkably improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a pharmacogenomics detection kit. Background Art

[0002] A pharmacogenomics detection kit is a key device for storing gene detection reagents and maintaining their biological activity, and is widely used in personalized medication guidance.

[0003] Currently, Chinese Patent Application No.: CN202120136793.5 discloses a pharmacogenomics detection kit, which includes a kit device main body, a classification mechanism, and a protection mechanism. The bottom of the kit device main body is fixedly connected with a classification mechanism, the top of the kit device main body is fixedly and movably connected with a protection mechanism, a protection baffle is embedded at the top of the protection mechanism, a protection ring is nested at the top of the protection baffle, a protection plate is embedded at the bottom of the protection ring, and a return spring is embedded in the middle of the protection plate.

[0004] However, the existing pharmacogenomics detection kits have defects such as cumbersome operation, single function, and insufficient protection: the cover body structure mostly adopts a single-side opening and closing or overall lid-lifting design, which requires two hands to operate and is prone to jamming due to uneven force; the temperature control module only supports a single temperature mode, and it is not easy to take into account various reagents that need to be refrigerated and stored at a constant temperature, forcing testers to rely on multiple devices, significantly increasing the operation complexity and space occupation; the test tube clamping mechanism is mostly a fixed card slot or a simple spring clip, with poor adaptability and weak earthquake resistance, and test tubes are prone to breakage or solution leakage due to vibration during transportation. Summary of the Invention

[0005] The purpose of the present invention is to provide a pharmacogenomics detection kit to solve the problems raised in the above background art.

[0006] To achieve the above object, the present invention adopts the following technical solutions: A pharmacogenomics detection kit, comprising a housing, a left cover, a right cover, a tube placement structure and a bin box mechanism. The left and right sides of the rear part of the housing are respectively hinged with a left cover and a right cover, and the front sides of the left cover and the right cover are both engaged with the housing. The interior of the housing is hollow, and a rectangular through groove is provided in the middle and lower part of the front part of the housing. A tube placement structure is arranged in the middle and lower part of the housing interior. Above the inner side of the tube placement structure, a bin box mechanism is arranged, and the left and right sides of the bin box mechanism are respectively fixed to the left and right inner walls of the housing. The tube placement structure includes a plate frame with a circular through groove inside, a rectangular block fixed to the rear side of the plate frame, a first connecting rod and a second connecting rod respectively rotatably connected to the upper and lower sides of the rectangular block, a sliding frame rotatably connected to the rear ends of the first connecting rod and the second connecting rod, a roller rotatably connected to the side of the first connecting rod near the sliding frame, a groove frame slidably wrapped around the outer surface of the roller, a sleeve rod fixed to the rear part of the rectangular block, and two inner rods slidably connected to the left and right sides inside the sleeve rod. The bottom of the sliding frame is slidably connected to the housing. The groove frame is fastened to the inner side wall of the housing. The plate frame is in a Z-shaped structure, and when the plate frame is located at the rearmost side, the bottom contacts the housing.

[0007] Preferably, a partition strip is arranged in the upper middle part of the housing interior, and the bottom of the partition strip contacts the bin box mechanism. Convex strips are arranged at the bottoms of the left and right inner side walls of the housing interior. A protrusion is arranged at the bottom position of the sliding frame close to the housing side wall, and the protrusion is slidably connected between the bottom side of the housing interior and the convex strip.

[0008] Preferably, there are two each of the first connecting rod, the second connecting rod, the sliding frame, the roller and the groove frame, and the two groups are arranged symmetrically left and right in the middle of the plate frame.

[0009] Preferably, a parallelogram structure is formed among the rectangular block, the first connecting rod, the second connecting rod and the sliding frame, and an arc-shaped groove is provided on the upper side of the front part of the sliding frame. When the plate frame is located at the rearmost side, the rotation axis of the roller is located inside the arc-shaped groove.

[0010] Preferably, a horizontal groove, an inclined groove and a sunken groove are arranged in the groove frame from back to front, and the horizontal groove, the inclined groove and the sunken groove are internally connected. During the forward movement of the plate frame, the roller is sequentially slidably connected inside the horizontal groove, the inclined groove and the sunken groove.

[0011] Preferably, the cartridge mechanism includes a cartridge body. On the upper sides of the left and right sides of the cartridge body, there are fixed connection pads, and the other sides of the pads are fixed to the housing. Inside the cartridge body, there are four loading bodies arranged in a row for loading reagent tubes. Inside the two loading bodies on the left, there is a semiconductor refrigeration sheet, and inside the two loading bodies on the right, there is a heating wire. The loading body includes a rectangular seat whose outer wall is fixed to the cartridge body. In the middle of the top of the rectangular seat, there is a through groove, and in the middle of the inside of the rectangular seat, there is a positioning structure. The bottom of the positioning structure is connected to a support piece. Inside the middle and lower part of the rectangular seat, there is a tightly fixed blower. Below the blower, there is a solenoid valve, and the solenoid valve is embedded in the inner side of the bottom of the rectangular seat. In the support piece, there is an air port for gas circulation.

[0012] Preferably, the positioning structure includes a cover seat whose bottom is tightly fixed to the support piece, a support block embedded in the inner side of the top of the cover seat, a columnar block fastened to the top side of the support block, three elastic clamping jaws connected to the top of the columnar block, and a top support assembly that wraps and slides on the outer surfaces of the three elastic clamping jaws. The middle of the top support assembly slides through the middle of the inside of the support block and the columnar block, and the bottom side of the top support assembly is arranged inside the cover seat.

[0013] Preferably, the included angle between two adjacent ones of the three elastic clamping jaws is 120 degrees, and the upper and middle parts of the three elastic clamping jaws are inclined outwards.

[0014] Preferably, the top support assembly includes a servo motor whose bottom is tightly fixed to the cover seat, a screw rod connected to the top output end of the servo motor, a spacer wrapped and rotated at the bottom of the screw rod, an internally threaded sleeve block threadedly connected to the outer surface of the screw rod, a push frame fixedly connected to the top side of the internally threaded sleeve block, a vertical rod connected to the middle of the top of the push frame, a sliding piece connected to the top end of the vertical rod, and a support seat fixedly connected to the middle of the top of the sliding piece. The spacer is fixedly connected to the bottom side inside the cover seat. The internally threaded sleeve block slides longitudinally on the inner wall of the cover seat. The vertical rod slides through the middle of the inside of the support block and the columnar block. The sliding piece wraps and slides on the outer surfaces of the elastic clamping jaws.

[0015] Preferably, on the left and right sides of the inner wall of the cover seat, there are longitudinal sliding grooves, and the left and right sides of the internally threaded sleeve block are respectively inserted and slide inside the two sliding grooves. Inside the sliding piece, there are three arc-shaped grooves, and the three arc-shaped grooves respectively wrap and slide on the outer surfaces of the three elastic clamping jaws.

[0016] Compared with the prior art, the beneficial effects of the present invention are:

[0017] The present invention realizes the integrated operation of opening the cover and pulling out and placing the test tubes with one hand through the coordinated design of the double-sided independent opening and closing cover body and the tube placement structure of the liftable test tube platform. The plate rack of the tube placement structure serves as an external platform for reagent tubes and adopts a mechanical linkage mechanism to drive a three-stage motion trajectory: it remains stable during horizontal movement, maintains the horizontal position of the plate rack and moves upward during the lifting stage, and the self-locking fixation at the end ensures that there is no risk of retraction during operation. The double-track sliding system eliminates lateral shaking, making the reagent tube taking and placing process accurate and smooth, greatly reducing the operational error rate, and ensuring the stability of the reagent tube placement.

[0018] A partition bar is provided on the upper middle side of the interior of the shell of the present invention, and the bottom of the partition bar is in contact with the bin box mechanism, thereby increasing the sealing effect and realizing the isolation of the left and right sides of the bin box mechanism, so as to form functional zoning of the bin box mechanism and improve the convenience of use. In addition, a semiconductor refrigeration and electric heating wire dual temperature zone module is integrated in the bin box mechanism to independently maintain the refrigeration and constant temperature environment. The circulating airflow system makes the gas flow through the air duct to evenly distribute the temperature field and eliminate local hot and cold deviations. The integrated design significantly reduces the volume of the equipment to meet the space restriction requirements of multiple scenarios.

[0019] The innovative clamping mechanism of the present invention controls the radial synchronous retraction and extension of three elastic claws through a top support assembly, seamlessly adapting to reagent tubes of different specifications. In the process of radial synchronous retraction and extension of the elastic claws, the top support assembly forms a support at the bottom of the reagent tube and cooperates with the three elastic claws to form a double fixation, effectively preventing the tube from tilting, breaking or solution leakage during transportation. The double clamping and positioning design ensures that the test kit maintains internal stability in a bumpy environment, making it suitable for field testing and long-distance transportation scenarios. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a structural schematic diagram of the present invention;

[0021] Figure 2 This is a schematic diagram of the structure of the present invention after the left cover and the right cover are removed;

[0022] Figure 3 This is a schematic structural diagram of the connection between the housing and the tube placement structure of the present invention;

[0023] Figure 4 It is a side view schematic diagram of the tube placement structure of the present invention;

[0024] Figure 5 Schematic diagram of the structure of the magazine mechanism of the present invention;

[0025] Figure 6 It is a structural schematic diagram of the positioning structure of the present invention;

[0026] Figure 7 It is a structural schematic diagram of the top support assembly of the present invention.

[0027] In the figure: housing - 1, left cover - 2, right cover - 3, catheter - placing structure - 4, bin - box mechanism - 5, partition strip - 11, rib - 12, plate - frame - 41, rectangular block - 42, first connecting rod - 43, second connecting rod - 44, sliding carriage - 45, roller - 46, groove - frame - 47, sleeve rod - 48, inner rod - 49, horizontal groove - 471, inclined groove - 472, sunken groove - 473, bin body - 51, cushion block - 52, rectangular seat - 53, through - slot - 54, positioning structure - 55, support piece - 56, fan - 57, solenoid valve - 58, cover - seat - 551, support block - 552, columnar block - 553, elastic jaw - 554, top - support assembly - 555, servo motor - 5551, screw rod - 5552, spacer - 5553, internally - threaded sleeve block - 5554, push - frame - 5555, vertical rod - 5556, sliding piece - 5557, support - seat - 5558. Detailed implementation manners

[0028] In order to further explain the technical solution of the present invention, the following will be elaborated in detail through specific embodiments.

[0029] Please refer to Figure 1 and Figure 2 The present invention provides a pharmacogenomics detection kit, including a housing 1, a left cover 2, a right cover 3, a catheter - placing structure 4 and a bin - box mechanism 5. Functional partitions are realized through modular design. The left and right sides of the rear part of the housing 1 are respectively hinged with a left cover 2 and a right cover 3, and the front sides of the left cover 2 and the right cover 3 are both engaged with the housing 1. The bilateral independent opening and closing structure facilitates single - hand operation, and the engagement design ensures the sealing and dust - proof performance during transportation. The interior of the housing 1 is in a hollow shape, and a rectangular through - slot is opened in the middle and lower part of the front of the housing 1. A catheter - placing structure 4 is arranged in the middle and lower part of the interior of the housing 1, and a bin - box mechanism 5 is arranged above the inner side of the catheter - placing structure 4. The catheter - placing structure 4 can be pulled out from below the bin - box mechanism 5 to facilitate the placement of reagents during use and prevent the reagents from tipping over. The left and right sides of the bin - box mechanism 5 are respectively fixed to the left and right inner walls of the housing 1. A partition strip 11 is arranged in the middle and upper part of the interior of the housing 1, and the bottom of the partition strip 11 is in contact with the bin - box mechanism 5, increasing the sealing effect and realizing the isolation of the left and right sides of the bin - box mechanism 5, so as to form functional partitions for the bin - box mechanism 5 and improve the convenience of use.

[0030] Please refer to Figures 1 - 4, the present invention provides a pharmacogenomics detection kit. The tube placement structure 4 includes a plate rack 41 with a circular through groove inside, a rectangular block 42 fixed to the rear side of the plate rack 41, a first connecting rod 43 and a second connecting rod 44 respectively rotatably connected to the upper and lower sides of the rectangular block 42, a carriage 45 rotatably connected to the rear ends of the first connecting rod 43 and the second connecting rod 44, a roller 46 rotatably connected to the side of the first connecting rod 43 near the carriage 45, a groove rack 47 slidably wrapped around the outer surface of the roller 46, a sleeve rod 48 fixedly connected to the rear part of the rectangular block 42, and two inner rods 49 slidably connected to the left and right sides inside the sleeve rod 48. The stable telescopic movement of the plate rack 41 is realized through a multi-link cooperation mechanism, so that the plate rack 41 can be moved into the housing 1 for storage or pulled out from the housing 1 and lifted upward to facilitate the placement of reagents, preventing the reagents from tipping over. Moreover, the inner rod 49 can be pulled out of the sleeve rod 48 to prevent the plate rack 41 from retracting when the plate rack 41 is at the most forward position, improving the stability effect of the plate rack 41. The bottom of the carriage 45 is slidably connected to the housing 1, the groove rack 47 is fastened to the inner side wall of the housing 1, the plate rack 41 has a Z-shaped structure, and when the plate rack 41 is at the rearmost side, the bottom contacts the housing 1. The Z-shaped bending structure improves the bearing stiffness and ensures the stability of the placement of reagent tubes.

[0031] Among them, convex strips 12 are provided at the bottoms of the left and right side walls inside the housing 1. A protrusion is provided at the bottom position of the carriage 45 close to the side wall of the housing 1, and the protrusion is slidably connected between the bottom side inside the housing 1 and the convex strip 12 to form a double-track sliding system to eliminate lateral shaking. The convex strip 12 constitutes an anti-derailment barrier. There are two first connecting rods 43, second connecting rods 44, carriages 45, rollers 46 and groove racks 47, and the two groups are symmetrically arranged left and right in the middle of the plate rack 41. A parallelogram structure is formed among the rectangular block 42, the first connecting rod 43, the second connecting rod 44 and the carriage 45. The parallelogram connecting rods ensure the horizontal displacement of the plate rack 41, so that the plate rack 41 remains horizontal after being pulled out, facilitating the placement of reagent tubes. An arc-shaped groove is opened on the upper side of the front part of the carriage 45. When the plate rack 41 is at the rearmost side, the shaft of the roller 46 is located inside the arc-shaped groove. A horizontal groove 471, an inclined groove 472 and a sunken groove 473 are opened in the groove rack 47 from back to front. The horizontal groove 471, the inclined groove 472 and the sunken groove 473 are internally connected. During the forward movement of the plate rack 41, the roller 46 is sequentially slidably connected inside the horizontal groove 471, the inclined groove 472 and the sunken groove 473. The movement trajectory is controlled by a three-stage guide groove. The horizontal groove 471 maintains the horizontal position of the plate rack 41, the inclined groove 472 makes the plate rack 41 slowly lift the height position during the pulling-out process, and the sunken groove 473 positions and locks, so that the plate rack 41 remains fixed in position when pulled out to the most forward side, improving the horizontal stability of the placement of reagent tubes.

[0032] Please refer to Figure 1 , Figure 2 , Figures 5 - 7, the present invention provides a pharmacogenomics detection kit. The bin mechanism 5 includes a bin body 51. On the upper sides of the left and right sides of the bin body 51, there are fixed connection pads 52, and the other side of the pads 52 is fixed to the housing 1, so as to install and position the bin body 51 through the pads 52. Inside the bin body 51, there are arranged four loading bodies for loading reagent tubes. On the inner sides of the two loading bodies on the left, there are semiconductor refrigeration chips, and on the inner sides of the two loading bodies on the right, there are heating wires. Through independent temperature control in the dual-temperature zones, a 4-degree refrigeration effect is presented in the two loading bodies on the left, and a 37-degree constant temperature effect is presented in the two loading bodies on the right, adapting to the preservation requirements of different reagents. The loading body includes a rectangular seat 53 whose outer wall is fixed to the bin body 51. In the middle of the top of the rectangular seat 53, there is a through groove 54, and in the middle of the inside of the rectangular seat 53, there is a positioning structure 55. The bottom of the positioning structure 55 is connected to the support piece 56. Under the action of the positioning structure 55, the reagent tube is stably clamped inside, and the bottom is supported by the positioning structure 55, forming an all-round positioning and clamping effect on different reagent tubes, ensuring stability during transportation. Inside the middle and lower part of the rectangular seat 53, there is a tightly fixed blower 57. Below the blower 57, there is a solenoid valve 58. The solenoid valve 58 is embedded in the inner side of the bottom of the rectangular seat 53. In the support piece 56, there are air ports for gas circulation. Through the cooperation of the solenoid valve 58 and the blower 57, an air flow circulation system is constructed to achieve uniform distribution of the temperature field and reduce the temperature difference.

[0033] Among them, the positioning structure 55 includes a cover seat 551 whose bottom is tightly fixed to the support piece 56, a support block 552 embedded in the inner side of the top of the cover seat 551, a columnar block 553 fastened to the top side of the support block 552, three elastic clamping claws 554 connected to the top of the columnar block 553, and a top support assembly 555 that wraps and slides on the outer surfaces of the three elastic clamping claws 554. The middle part of the top support assembly 555 passes through and slides in the middle of the inside of the support block 552 and the columnar block 553, and the bottom side of the top support assembly 555 is arranged inside the cover seat 551. Through the top support assembly 555, the tension of the three elastic clamping claws 554 can be changed to adapt to the diameters of various reagent tubes. And after the longitudinal movement of the top support assembly 555, the top contacts the bottom side of the reagent tube, improving the clamping and positioning effect on the reagent tube. The included angle between two adjacent ones of the three elastic clamping claws 554 is 120 degrees, and the upper and middle parts of the three elastic clamping claws 554 are all inclined outward, so as to facilitate clamping and positioning of the reagent tube and ensure the stability of the reagent tube.

[0034] Among them, the top support assembly 555 includes a servo motor 5551 with its bottom fastened to the cover base 551, a screw rod 5552 connected to the top output end of the servo motor 5551, a spacer 5553 wrapped around and rotating at the bottom of the screw rod 5552, an internally threaded sleeve block 5554 threadedly connected to the outer surface of the screw rod 5552, a push frame 5555 fixedly connected to the top side of the internally threaded sleeve block 5554, a vertical rod 5556 connected to the middle side of the top of the push frame 5555, a sliding piece 5557 connected to the top end of the vertical rod 5556, and a support 5558 fixedly connected to the middle side of the top of the sliding piece 5557. Using the servo motor 5551 as the power source, through the cooperation of the screw rod 5552 and the internally threaded sleeve block 5554, the height position of the vertical rod 5556 can be precisely adjusted up and down, so as to facilitate driving the heights of the sliding piece 5557 and the support 5558 to be adjusted, enabling the support 5558 to contact and form a supporting effect under the reagent tube. The spacer 5553 is fixedly connected to the inner bottom side of the cover base 551. The vertical rod 5556 penetrates and slides in the middle sides of the support block 552 and the columnar block 553, ensuring the stability of the longitudinal displacement of the vertical rod 5556. Longitudinal chutes are provided on both the left and right sides of the inner wall of the cover base 551, and the left and right sides of the internally threaded sleeve block 5554 are respectively inserted and slide inside the two chutes, ensuring the stability of the longitudinal displacement of the internally threaded sleeve block 5554. Three arc-shaped grooves are provided inside the sliding piece 5557, and the three arc-shaped grooves respectively wrap around and slide on the outer surfaces of the three elastic clamping jaws 554, so as to guide the synchronous expansion and contraction of the three elastic clamping jaws 554 through the change of the longitudinal position of the sliding piece 5557, generating different clamping forces and ensuring the stable clamping effect of the three elastic clamping jaws 554 on the reagent tube.

[0035] A pharmacogenomics detection kit of the present invention realizes its functions through the following collaborative working mechanisms:

[0036] First, modular structure linkage:

[0037] The housing 1 is designed with independent opening and closing on both sides of the left cover 2 and the right cover 3, enabling one-handed operation for opening and closing. The tube placement structure 4 adopts a parallelogram linkage mechanism formed by a rectangular block 42, a first connecting rod 43, a second connecting rod 44, and a sliding carriage 45, and completes a three-stage movement by pulling the Z-shaped plate frame 41: when initially stored, the plate frame 41 is horizontally placed inside the housing; when pulled out, the roller 46 translates along the horizontal groove 471 of the groove frame 47, and after entering the inclined groove 472, the plate frame 41 remains horizontal and moves upward; when reaching the sunken groove 473, the roller 46 falls into the sunken groove 473 to generate self-locking and fixation, forming a stable operation platform; after the plate frame 41 is pulled out, the inner rod 49 can be further pulled out from the side of the sleeve rod 48 through the telescopic cooperation of the sleeve rod 48 and the inner rod 49 to further prevent the plate frame 41 from retracting, and the reagent tube can be stably placed inside the plate frame 41;

[0038] Second, dual-temperature zone dynamic temperature control:

[0039] The left area of the bin box mechanism 5 loads a semiconductor refrigeration chip to achieve 4°C refrigeration, and the right area maintains a constant temperature of 37°C through a heating wire; after the air flow is driven by the fan 57 and adjusted by the solenoid valve 58, a circulating air duct is formed from the air port of the support piece 56, so as to improve the temperature field uniformity and ensure the temperature control effect of the reagent tube clamped and positioned inside the positioning structure 55;

[0040] Third, the adaptive clamping system:

[0041] The positioning structure 55 drives the screw rod 5552 through the servo motor 5551, drives the internally threaded sleeve block 5554 to move vertically along the chute, and makes the arc groove of the sliding piece 5557 slide longitudinally along the surface of the elastic claw 554, so as to control the expansion and contraction of the elastic claw. When the sliding piece 5557 moves upward and the three elastic claws 554 are tightened and contact the surface of the reagent tube to achieve radial clamping; at the same time, during the upward displacement movement of the sliding piece 5557, the support 5558 synchronously moves longitudinally, and after the support 5558 moves upward, it supports against the bottom of the reagent tube to form axial positioning, forming a dual fixing mechanism of three-point clamping + bottom lifting to ensure the clamping and positioning effect of reagent tubes of different sizes.

[0042] The above are only the preferred examples of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A pharmacogenomics detection kit, comprising a housing (1), characterized in that: On the left and right sides of the rear part of the housing (1), a left cover (2) and a right cover (3) are respectively hinged, and the front sides of the left cover (2) and the right cover (3) are both engaged with the housing (1). The interior of the housing (1) is hollow, and a rectangular through groove is provided in the middle and lower part of the front of the housing (1). A pipe placement structure (4) is provided in the middle and lower part of the interior of the housing (1). Above the inner side of the pipe placement structure (4), a bin box mechanism (5) is provided. The left and right sides of the bin box mechanism (5) are respectively fixed to the left and right inner walls of the housing (1). The pipe placement structure (4) includes a plate frame (41) with a circular through groove inside, a rectangular block (42) fixed to the rear side of the plate frame (41), a first connecting rod (43) and a second connecting rod (44) respectively rotatably connected to the upper and lower sides of the rectangular block (42), a sliding frame (45) rotatably connected to the rear ends of the first connecting rod (43) and the second connecting rod (44), a roller (46) rotatably connected to the side of the first connecting rod (43) near the sliding frame (45), a groove frame (47) wrapped and sliding on the outer surface of the roller (46), a sleeve rod (48) fixedly connected to the rear part of the rectangular block (42), and two inner rods (49) slidably connected to the left and right sides inside the sleeve rod (48). The bottom of the sliding frame (45) is slidably connected to the housing (1). The groove frame (47) is fastened to the inner side wall of the housing (1). The plate frame (41) is in a Z-shaped structure, and when the plate frame (41) is located at the rearmost side, the bottom contacts the housing (1).

2. The drug genomics detection kit according to claim 1, wherein: A partition strip (11) is provided in the upper middle part of the interior of the housing (1), and the bottom of the partition strip (11) contacts the bin box mechanism (5). Convex strips (12) are provided at the bottoms of the left and right inner side walls of the housing (1). A protrusion is provided at the bottom position of the sliding frame (45) close to the side wall of the housing (1), and the protrusion is slidably connected between the bottom side inside the housing (1) and the convex strip (12).

3. The drug genomics detection kit according to claim 1, wherein: There are two each of the first connecting rod (43), the second connecting rod (44), the sliding frame (45), the roller (46) and the groove frame (47), and the two groups are arranged symmetrically left and right in the middle of the plate frame (41).

4. The pharmaceutical genomics detection kit according to claim 1, wherein: A parallelogram structure is formed among the rectangular block (42), the first connecting rod (43), the second connecting rod (44) and the sliding frame (45). An arc groove is provided on the upper side of the front part of the sliding frame (45). When the plate frame (41) is at the rearmost side, the rotation axis of the roller (46) is located inside the arc groove.

5. The pharmaceutical genomics detection kit according to claim 1, characterized in that: A horizontal groove (471), an inclined groove (472) and a sunken groove (473) are provided in the groove frame (47) from back to front. The horizontal groove (471), the inclined groove (472) and the sunken groove (473) are internally connected. During the forward movement of the plate frame (41), the roller (46) is sequentially slidably connected inside the horizontal groove (471), the inclined groove (472) and the sunken groove (473).

6. The drug genomics detection kit according to claim 1, characterized in that: The cartridge mechanism (5) includes a cartridge body (51). On the upper sides of the left and right sides of the cartridge body (51), pads (52) are fixedly connected, and the other sides of the pads (52) are fixed to the housing (1). Inside the cartridge body (51), four loading bodies for loading reagent tubes are arranged in a row. A semiconductor refrigerating sheet is arranged inside the two loading bodies on the left, and heating wires are arranged inside the two loading bodies on the right. The loading body includes a rectangular seat (53) whose outer wall is fixed to the cartridge body (51). A through slot (54) is opened in the middle of the top of the rectangular seat (53), and a positioning structure (55) is arranged in the middle of the rectangular seat (53). The bottom of the positioning structure (55) is connected to a support piece (56). A fan (57) is fastened inside the lower middle part of the rectangular seat (53). A solenoid valve (58) is arranged below the fan (57). The solenoid valve (58) is embedded in the inner side of the bottom of the rectangular seat (53). An air port for gas flow is opened inside the support piece (56).

7. The drug genomics detection kit according to claim 6, wherein: The positioning structure (55) includes a cover seat (551) whose bottom is fastened to the support piece (56), a support block (552) embedded in the inner side of the top of the cover seat (551), a columnar block (553) fastened to the top side of the support block (552), three elastic clamping jaws (554) connected to the top of the columnar block (553), and a top support assembly (555) that wraps and slides on the outer surfaces of the three elastic clamping jaws (554). The middle part of the top support assembly (555) slides through the middle of the support block (552) and the columnar block (553), and the bottom side of the top support assembly (555) is arranged inside the cover seat (551).

8. The drug genomics detection kit according to claim 7, characterized in that: The included angle between every two adjacent ones of the three elastic clamping jaws (554) is 120 degrees, and the upper parts of the three elastic clamping jaws (554) are all inclined outward.

9. The pharmaceutical genomics detection kit according to claim 7, characterized in that: The top support assembly (555) includes a servo motor (5551) whose bottom is fastened to the cover seat (551), a screw rod (5552) connected to the top output end of the servo motor (5551), a spacer (5553) that wraps and rotates around the bottom of the screw rod (5552), an internally threaded sleeve block (5554) threadedly connected to the outer surface of the screw rod (5552), a push frame (5555) fixedly connected to the top side of the internally threaded sleeve block (5554), a vertical rod (5556) connected to the middle of the top of the push frame (5555), a sliding piece (5557) connected to the top end of the vertical rod (5556), and a support (5558) fixedly connected to the middle of the top of the sliding piece (5557). The spacer (5553) is fixedly connected to the inner bottom side of the cover seat (551). The internally threaded sleeve block (5554) slides longitudinally on the inner wall of the cover seat (551). The vertical rod (5556) slides through the middle of the support block (552) and the columnar block (553). The sliding piece (5557) wraps and slides on the outer surfaces of the elastic clamping jaws (554).

10. The drug genomics detection kit according to claim 9, wherein: Longitudinal sliding grooves are formed on the left and right sides of the inner wall of the cover base (551), and the left and right sides of the internally threaded sleeve block (5554) are respectively inserted and slide inside the two sliding grooves. Three arc-shaped grooves are arranged inside the sliding piece (5557), and the three arc-shaped grooves respectively wrap and slide on the outer surfaces of the three elastic clamping jaws (554).

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