Plasma instant freezer

Abstract

The invention provides a plasma instant freezer. The plasma instant freezer comprises a mounting table; the lower refrigeration unit comprises a first refrigeration module, the first refrigeration module is arranged below the mounting table, and the cold end of the first refrigeration module makes contact with the bottom of the mounting table; the upper refrigeration unit is arranged on the mounting table in an inverted mode and comprises a mounting plate, a second refrigeration module is arranged on the mounting plate, a pressing plate is arranged at the bottom of the mounting plate, and the cold end of the second refrigeration module is transmitted into the pressing plate through a heat conduction module; a plurality of pressing feet movably connected with the pressing plate in the vertical direction are arranged in the pressing plate. And the lifting unit enables the lower refrigeration unit and the upper refrigeration unit to move relatively. The height of the presser foot can be automatically adjusted, the presser foot is automatically and tightly attached to the upper surface of the blood bag under the support of the spring, the blood bags of different specifications can be quickly frozen at the same time, the blood bags do not need to be additionally classified, and use is more convenient.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, in particular to a plasma quick-freezing machine. Background Art

[0002] Plasma quick freezer is a key device used in the medical field to quickly freeze plasma and other biological samples. Its core requirement is to reduce the temperature of the center of the blood bag to below -30℃ within 30 minutes. The shorter the time, the better the blood activity can be guaranteed.

[0003] In existing technologies, mainstream plasma quick-freezing machines primarily use compressor refrigeration or liquid nitrogen refrigeration technology, employing contact-type pressure freezing on the upper and lower sides of the blood bag. Compressor refrigeration suffers from relatively low refrigeration efficiency, long freezing times, and large equipment size, making it unsuitable for use in laboratories with limited space. Liquid nitrogen refrigeration also suffers from high liquid nitrogen consumption, high operating costs, and safety risks associated with its storage and transportation. Furthermore, due to the varying heights of blood bags of varying sizes, freezing them together prevents the upper pressure plate of the quick-freezing machine from reaching the upper surface of the shorter bag, necessitating separate quick-freezing of each bag. Summary of the Invention

[0004] In order to solve the problem in the prior art that blood bags of different specifications need to be quickly frozen separately, the present invention provides a plasma quick freezing machine, comprising:

[0005] Mounting table;

[0006] a lower refrigeration unit, the lower refrigeration unit comprising a first refrigeration module, the first refrigeration module being disposed below the mounting platform, a cold end of the first refrigeration module being in contact with a bottom of the mounting platform;

[0007] An upper refrigeration unit is provided upside down on a mounting platform and includes a mounting plate, a second refrigeration module is provided on the mounting plate, a pressing plate is provided at the bottom of the mounting plate, the cold end of the second refrigeration module is transferred to the pressing plate via the heat conduction module, and a plurality of pressing feet are provided in the pressing plate that are movably connected to the pressing plate in a vertical direction;

[0008] The lifting unit is arranged at the bottom of the lower refrigeration unit or the top of the upper refrigeration unit, so that the lower refrigeration unit and the upper refrigeration unit move relative to each other.

[0009] Specifically, the first refrigeration module and the second refrigeration module are Stirling refrigerators.

[0010] Specifically, the heat conduction module includes a heat conduction plate and a heat pipe, the cold end of the second refrigeration module is fixedly mounted on the heat conduction plate, the upper end of the heat pipe is connected to the bottom of the heat conduction plate, and the lower end of the heat pipe is fixedly connected to the pressure plate.

[0011] Specifically, the pressure plate is provided with a plurality of through holes arranged in an array, the pressure foot is provided in the through hole, the pressure foot includes a contact plate, a guide wall and a fixed plate, a plurality of guide columns are provided at the bottom of the through hole, a plurality of guide grooves matching the guide columns are provided in the guide wall, the guide columns are embedded in the guide grooves, a spring is provided on the periphery of the guide wall, and the spring is clamped between the pressure plate and the contact plate.

[0012] Specifically, the heat pipes are distributed between two adjacent through holes in the pressing plate at equal intervals, and the heat pipes are L-shaped, so that a gap is separated between the pressing plate and the mounting plate.

[0013] Specifically, an insulation wall is provided on the periphery of the mounting plate to form a closed low-temperature cavity between the upper refrigeration unit and the mounting platform. Multiple layers of vacuum insulation layers are provided in the insulation wall and the mounting plate, and a flexible insulation layer is provided at the bottom of the insulation wall.

[0014] Specifically, the flexible thermal insulation layer is silicone rubber.

[0015] Specifically, the lifting unit includes an electric telescopic rod arranged on the top of the mounting plate and a guide slide rail arranged on the back of the insulation wall. Mounting frames are provided on both sides of the mounting platform. The fixed end of the electric telescopic rod is mounted upside down on the bottom of the mounting frame, and the telescopic end of the electric telescopic rod is fixedly connected to the mounting plate. A guide slider matching the guide slide rail is provided on the back of the insulation wall, and the guide slider is slidably connected to the guide slide rail.

[0016] Specifically, at least two first refrigeration modules are provided in the lower refrigeration unit, and at least two second refrigeration modules are provided in the upper refrigeration unit.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] 1. The present invention provides a plasma quick-freezing machine. Blood bags of any specifications can be placed at any position in a single tray. When blood bags of different specifications are placed in the freezer, the height can be automatically adjusted by the presser foot. The presser foot automatically and tightly fits the upper surface of the blood bag under the support of a spring. When quick-freezing blood bags, there is no need to additionally classify the blood bags and freeze them separately according to their categories, which makes it more convenient to use.

[0019] 2. The present invention adopts a Stirling refrigerator for refrigeration. Compared with conventional compression refrigeration systems, it has a strong rapid cooling capability and lower noise. The Stirling refrigerator can cool the blood bag from room temperature to the target temperature within a few minutes, so that the center point temperature of the blood bag can be quickly reduced to below -30°C, meeting the rapid cooling requirements of the blood bag. In addition, the Stirling refrigerator can be recycled and has low operating costs.

[0020] 3. Each refrigeration unit of the present invention adopts multiple Stirling refrigerators. Each refrigeration module can be started and stopped independently. When fewer blood bags need to be frozen, only the refrigeration unit covering the blood bag area can be turned on to reduce ineffective energy consumption. Multiple refrigeration modules form a fault-tolerant mechanism. If a single refrigeration module fails, it can still be used normally. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the overall structure of the plasma quick freezing machine of the present invention;

[0022] Figure 2 This is a schematic diagram of the internal structure of the plasma quick freezing machine of the present invention;

[0023] Figure 3 This is a schematic diagram of the internal structure of the refrigeration unit of the present invention;

[0024] Figure 4 This is a schematic diagram of the pressing plate structure of the present invention;

[0025] Figure 5 It is a schematic structural diagram of the presser foot of the present invention.

[0026] Figure numerals: 1. Mounting table; 11. Fixing frame; 12. Mounting frame; 2. Lower refrigeration unit; 21. First refrigeration module; 3. Upper refrigeration unit; 31. Mounting plate; 32. Second refrigeration module; 33. Heat conduction plate; 34. Heat pipe; 35. Pressing plate; 351. Guide column; 36. Presser foot; 361. Contact plate; 362. Guide wall; 363. Fixing plate; 364. Spring; 365. Guide groove; 37. Insulation wall; 38. Flexible insulation layer; 4. Lifting unit; 41. Slide rail; 42. Electric telescopic rod. DETAILED DESCRIPTION

[0027] The following embodiments of the present invention are described in further detail with reference to the accompanying drawings and examples. The following examples are used to illustrate the present invention but are not intended to limit the scope of the present invention.

[0028] In the description of the present invention, unless otherwise specified, "plurality" means two or more. Terms such as "upper," "lower," "left," "right," "inner," "outer," "front," and "rear" indicate positions or relationships based on those shown in the accompanying drawings. These terms are intended solely to facilitate and simplify the description of the present invention and are not intended to indicate or imply that the devices or components referred to must have, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on the present invention. Furthermore, terms such as "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0029] like Figure 1-Figure 5As shown, the present invention provides a plasma quick-freezing machine, including a mounting platform 1, a lower refrigeration unit 2, an upper refrigeration unit 3 and a lifting unit 4. A pressing plate 35 and a plurality of presser feet 36 movably connected to the pressing plate 35 along the vertical direction are provided in the upper refrigeration unit 3. The presser feet 36 are provided on the blood bag. During the pressing process, the contact between the presser feet 36 and the blood bag makes the presser feet 36 suitable for multiple blood bags of different specifications, thereby realizing one-time quick freezing of multiple blood bags of different specifications.

[0030] Mounting platform 1 is used to hold trays, which contain blood bags to be frozen. Mounting platforms 1 have mounting brackets 12 on either side of a fixed frame 11 at the bottom. Mounting bracket 11 houses a lower refrigeration unit 2, which includes at least two first refrigeration modules 21. The cold ends of these first refrigeration modules 21 are in direct contact with the bottom of the mounting platform 1, rapidly freezing the bottoms of the blood bags placed on the mounting platform. These first refrigeration modules 21 utilize Stirling refrigerators, which achieve low-temperature refrigeration through the isothermal compression, isothermal expansion, and isochoric reheating of gases.

[0031] Above the mounting frame 12, an upper refrigeration unit 3 is installed in an inverted manner. The upper refrigeration unit 3 includes a mounting plate 31. At least two second refrigeration modules 32 are installed on the mounting plate 31, and the cold ends of the second refrigeration modules 32 are arranged downward. A heat conduction module is installed below the mounting plate 31, and the cold ends of the second refrigeration modules 32 are connected to the heat conduction module. The heat conduction module includes a heat conduction plate 33 and a heat pipe 34. The cold end of the second refrigeration module 32 is fixedly installed on the heat conduction plate 33. The heat pipe 34 is connected to the bottom of the heat conduction plate 33. A low-temperature working fluid, such as acetone, propane, etc., is installed in the heat pipe 34. One end of the heat pipe 34 is fixedly connected to the mounting plate 31, and the other end is fixedly connected to the pressure plate 35. The heat pipe 34 efficiently transfers the cooling capacity of the second refrigeration module 32 from the heat conduction plate 33 to the pressure plate 35 through the internal working fluid phase change cycle.

[0032] The pressure plate 35 is disposed at the bottom of the mounting plate 31. The pressure plate 35 is provided with a plurality of through holes arranged in an array. A plurality of presser feet 36 that can move in a vertical direction are disposed in the through holes. The presser feet 36 include a contact plate 361, a guide wall 362, and a fixed plate 363. The fixed plate 363 is fixedly connected to the guide wall 362 by bolts. A plurality of guide posts 351 are disposed at the bottom of the through holes. The guide walls 362 are provided with a plurality of guide grooves 365 that match the guide posts 351. The guide posts 351 are embedded in the guide grooves 365, so that the vertical movement of the guide posts 351 is delayed when the pressure foot 36 moves. The guide posts 351 are in direct contact with the guide grooves 365, increasing the contact area between the presser feet 36 and the pressure plate 35 and improving the transfer rate of cooling capacity. A spring 364 is installed around the outer periphery of the guide wall 362. Spring 364 is clamped between the pressure plate 35 and the contact plate 361. When the blood bag is pressed, the elastic force of spring 364 forces the contact plate 361 to adhere tightly to the blood bag. Spring 364 is a low-temperature-resistant spring, maintaining excellent toughness and elasticity even in low-temperature environments. Heat pipes 34 are evenly spaced between adjacent through-holes in the pressure plate 35. The heat pipes 34 are L-shaped, creating a gap between the pressure plate 35 and the mounting plate 31, providing space for the vertical movement of the pressure foot 36.

[0033] The refrigeration unit adopts a presser foot 36 design. The cold capacity of the second refrigeration module 32 is quickly transferred to the surface of the blood bag through the mounting plate 31, the heat pipe 34 and the pressure plate 35. Blood bags of any specifications can be placed at any position in a single tray. When blood bags of different specifications are placed in the freezer, the height of the presser foot 36 can be automatically adjusted. The presser foot 36 automatically fits tightly to the upper surface of the blood bag under the support of the spring 364. When quick-freezing the blood bags, there is no need to additionally classify the blood bags and freeze them separately according to categories, which is more convenient to use.

[0034] To reduce energy consumption, mounting plate 31 is constructed of insulating material. An insulating wall 37 is installed around the periphery of mounting plate 31. Multiple layers of vacuum insulation are incorporated within the insulating wall 37 and the mounting plate 31. A flexible insulating layer 38 is installed at the bottom of the insulating wall 37. Silicone rubber, with a thermal conductivity of approximately 0.04-0.08 W / m∙K and a low-temperature brittleness temperature below -60°C, ensures a tight seal. When the lifting unit 4 lowers the upper refrigeration unit 3, the flexible insulating layer 38 on the bottom of the insulating wall 37 adheres tightly to the top surface of the mounting platform 1, creating a sealed low-temperature cavity between the upper refrigeration unit 3 and the mounting platform 1. This isolates the upper refrigeration unit 3 from external hot air and prevents frost formation and cold air leakage within the cavity. An insulating coating is applied to the surfaces of the heat pipe 34, mounting plate 31, and the top surface of the pressure plate 35, effectively minimizing cold loss and reducing energy consumption during cold transfer.

[0035] The lifting unit 4 is connected to the mounting platform 1 or the upper refrigeration unit 3 and is used to enable relative movement between the mounting platform 1 and the upper refrigeration unit 3 so that the presser foot 36 is attached to the upper surface of the blood bag. Preferably, the lifting unit 4 is installed in the upper refrigeration unit 3 so that the upper refrigeration unit 3 moves downward to press the upper surface of the blood bag. The lifting unit 4 includes an electric telescopic rod 42 arranged on the top of the mounting plate 31 and a guide rail 41 arranged on the back of the insulation wall 37. The fixed end of the electric telescopic rod 42 is mounted upside down on the bottom of the mounting frame 12, and the telescopic end of the electric telescopic rod 42 is fixedly connected to the mounting plate 31. The back of the insulation wall 37 is provided with a guide slider that matches the guide rail 41. The guide slider is slidably connected to the guide rail 41, and the vertical movement of the upper refrigeration unit 3 is guided by the guide slider. In addition, the lifting unit 4 can also be set at the bottom of the mounting platform 1, and the presser foot 36 is attached to the upper surface of the blood bag by lifting the mounting platform 1.

[0036] The first refrigeration module 21 and the second refrigeration module 32 are Stirling refrigerators. These refrigerators are compact and offer rapid cooling capabilities and quieter operation compared to conventional compression refrigeration systems. They can cool blood bags from ambient temperature to the target temperature within minutes, rapidly reducing the center temperature of the blood bag to below -30°C, meeting the rapid cooling requirements. Compared to liquid nitrogen refrigeration, Stirling refrigerators are recyclable and cost-effective. During the freezing process, a fuzzy logic-based PID control algorithm generates a speed adjustment gradient based on the load and temperature change rate, enabling more precise temperature control.

[0037] The lower refrigeration unit 2 is equipped with at least two first refrigeration modules 21, and the upper refrigeration unit 3 is equipped with at least two second refrigeration modules 32. Each refrigeration module can be started and stopped independently. When fewer blood bags need to be frozen, only the refrigeration unit covering the blood bags can be activated, reducing inefficient energy consumption. Multiple refrigeration modules form a fault-tolerant mechanism, ensuring normal operation even if a single refrigeration module fails.

[0038] During use, the blood bag placed in the tray is placed on the mounting table 1, and the plasma quick freezer is started. The lifting unit 4 controls the upper refrigeration unit 3 to descend, so that the upper refrigeration unit 3 and the mounting table 1 form a closed chamber. The contact surface of the presser foot 36 is directly attached to the upper surface of the blood bag based on the height of the blood bag, and the blood bag is flattened under the elastic force of the spring 364. Then the first refrigeration module 21 and the second refrigeration module 32 are started to cool the blood bag from the upper and lower sides at the same time, and the center point temperature of the blood bag is quickly reduced to below -30°C. After the freezing is completed, the lifting unit 4 controls the upper refrigeration unit 3 to rise, and the tray is taken out to complete the first quick freezing of the blood bag.

[0039] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any modifications or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in the present invention should be included in the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be based on the scope of protection of the claims.

Claims

1. A plasma quick freezing machine, characterized in that: include: Mounting table; a lower refrigeration unit, the lower refrigeration unit comprising a first refrigeration module, the first refrigeration module being disposed below the mounting platform, a cold end of the first refrigeration module being in contact with a bottom of the mounting platform; An upper refrigeration unit is provided upside down on a mounting platform and includes a mounting plate, a second refrigeration module is provided on the mounting plate, a pressing plate is provided at the bottom of the mounting plate, the cold end of the second refrigeration module is transferred to the pressing plate via the heat conduction module, and a plurality of pressing feet are provided in the pressing plate that are movably connected to the pressing plate in a vertical direction; The lifting unit is arranged at the bottom of the lower refrigeration unit or the top of the upper refrigeration unit, so that the lower refrigeration unit and the upper refrigeration unit move relative to each other.

2. The plasma quick freezing machine according to claim 1, characterized in that The first refrigeration module and the second refrigeration module are Stirling refrigerators.

3. The plasma quick freezing machine according to claim 1, characterized in that The heat conduction module includes a heat conduction plate and a heat pipe. The cold end of the second refrigeration module is fixedly mounted on the heat conduction plate. The upper end of the heat pipe is connected to the bottom of the heat conduction plate, and the lower end of the heat pipe is fixedly connected to the pressing plate.

4. The plasma quick freezing machine according to claim 3, characterized in that The pressure plate is provided with a plurality of through holes arranged in an array, the pressure foot is provided in the through hole, the pressure foot includes a contact plate, a guide wall and a fixed plate, a plurality of guide posts are provided at the bottom of the through hole, a plurality of guide grooves matching the guide posts are provided in the guide wall, the guide posts are embedded in the guide grooves, a spring is provided on the outer periphery of the guide wall, and the spring is clamped between the pressure plate and the contact plate.

5. The plasma quick freezing machine according to claim 4, characterized in that The heat pipes are distributed between two adjacent through holes in the pressing plate at equal intervals. The heat pipes are L-shaped, so that a gap is separated between the pressing plate and the mounting plate.

6. The plasma quick freezing machine according to claim 1, characterized in that An insulation wall is provided on the periphery of the mounting plate to form a closed low-temperature cavity between the upper refrigeration unit and the mounting platform. Multiple layers of vacuum insulation layers are provided in the insulation wall and the mounting plate, and a flexible insulation layer is provided at the bottom of the insulation wall.

7. The plasma quick freezing machine according to claim 6, characterized in that The flexible thermal insulation layer is made of silicone rubber.

8. The plasma quick freezing machine according to claim 6, characterized in that: The lifting unit includes an electric telescopic rod arranged on the top of the mounting plate and a guide slide rail arranged on the back of the insulation wall. Mounting frames are provided on both sides of the mounting platform. The fixed end of the electric telescopic rod is mounted upside down on the bottom of the mounting frame. The telescopic end of the electric telescopic rod is fixedly connected to the mounting plate. A guide slider matching the guide slide rail is provided on the back of the insulation wall, and the guide slider is slidably connected to the guide slide rail.

9. The plasma quick freezing machine according to claim 1, characterized in that At least two first refrigeration modules are provided in the lower refrigeration unit, and at least two second refrigeration modules are provided in the upper refrigeration unit.

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