Cerebrospinal fluid replacement and purification device

Abstract

The invention discloses a cerebrospinal fluid replacement and purification device, and relates to the field of medical equipment, the cerebrospinal fluid replacement and purification device comprises a pumping-in replacement system and a pumping-out replacement system, the pumping-in replacement system comprises a first liquid pump and a first storage bag, the pumping-out replacement system comprises a second liquid pump, a second storage bag and a third storage bag, the output end of the first liquid pump is connected with a first transmission pipeline, and the output end of the second liquid pump is connected with a second transmission pipeline; the first transmission pipeline is connected with the input end of the defoamer, the output end of the second liquid pump is connected with a second transmission pipeline, the second transmission pipeline is a three-way pipeline, and the other two ends of the second transmission pipeline are connected with the main filter and the standby filter respectively. Cerebrospinal fluid is filtered in a circulating replacement mode, stability of intracranial pressure is guaranteed, basic guarantee is provided for normal input and discharge of the cerebrospinal fluid, the environment in a cranial cavity is optimized, the mode of directly replacing artificial cerebrospinal fluid is replaced, only a small part of artificial cerebrospinal fluid is left in the cranial cavity, component balance of the cerebrospinal fluid cannot be affected, and the safety of the cranial cavity is improved. And the device is more suitable for different people.

Description

Technical Field

[0001] The present invention relates to the field of medical equipment, in particular to a cerebrospinal fluid replacement and purification device. Background Art

[0002] Cerebrospinal fluid replacement is a medical technique used to treat cerebrospinal fluid-related diseases. It is widely used in the treatment of diseases such as meningitis, ventriculitis, and cerebrospinal fluid circulation disorders. Traditional cerebrospinal fluid replacement methods mainly drain the cerebrospinal fluid in the patient's ventricles or cisterns through drainage and perfusion, while injecting artificial cerebrospinal fluid or saline to purify the cerebrospinal fluid, reduce brain edema, and lower intracranial pressure. However, the existing technology has the following problems:

[0003] First, in traditional cerebrospinal fluid replacement, the drainage and perfusion rates are difficult to precisely control, which can easily lead to fluctuations in intracranial pressure. Excessive or low intracranial pressure can damage brain tissue and affect the patient's recovery.

[0004] Second: During the cerebrospinal fluid replacement process, bubbles in the fluid may enter the cranial cavity, causing serious medical problems such as air embolism. Traditional defoaming methods mainly reduce bubbles through physical stirring, but these methods have limited effects and may affect the composition of the cerebrospinal fluid;

[0005] Third: Traditional cerebrospinal fluid replacement systems usually use a single-layer filter membrane for filtration, which has a limited filtration area and is prone to clogging, resulting in a decrease in filtration efficiency. In addition, a single-layer filter membrane is difficult to completely remove pathogens and blood cells in the cerebrospinal fluid, affecting the replacement effect.

[0006] Therefore, it is necessary to propose a cerebrospinal fluid replacement and purification device to solve the above problems. Summary of the Invention

[0007] The purpose of the present invention is to provide a cerebrospinal fluid replacement and purification device to achieve the purpose of filtering and purifying cerebrospinal fluid, and to ensure stable intracranial pressure during the replacement process.

[0008] To achieve the above-mentioned object, the present invention provides the following technical solution: a cerebrospinal fluid replacement and purification device, comprising:

[0009] A pumping replacement system, comprising a first liquid pump and a first storage bag, wherein the first storage bag is used to store artificial cerebrospinal fluid, the first storage bag is connected to the input end of the first liquid pump, the output end of the first liquid pump is connected to a first transmission pipeline, the first transmission pipeline is connected to the input end of a defoamer, the output end of the defoamer is provided with a pumping pipeline, and the end of the pumping pipeline is butted with a pipeline connector;

[0010] When the first liquid pump is started, the artificial cerebrospinal fluid stored in the first storage bag is pumped out, and the defoamer is used to eliminate bubbles in the cerebrospinal fluid;

[0011] A pump-out replacement system, comprising a second liquid pump, a second storage bag, and a third storage bag; the input end of the second liquid pump is connected to a pump-out pipe, which is connected to another set of pipe connectors; the output end of the second liquid pump is connected to a second transmission pipe, which is a three-way pipe; the other two ends of the second transmission pipe are respectively connected to a main filter and a backup filter; cerebrospinal fluid passing through the second transmission pipe is filtered through the main filter and the backup filter to remove pathogens and blood cells; the output ends of the main filter and the backup filter are both connected to the input end of the second storage bag and the input end of the third storage bag; the cerebrospinal fluid is filtered through the main filter or the backup filter to form clean cerebrospinal fluid, pathogens, and blood cells;

[0012] Among them, clean cerebrospinal fluid is collected into the second storage bag, and pathogens and blood cells are collected into the third storage bag;

[0013] The output end of the second storage bag is connected to a reflux pipe, which is connected to the first liquid pump, and the clean cerebrospinal fluid in the second storage bag is further pumped into the cranial cavity through the first liquid pump;

[0014] Holes leading to the cranial cavity are drilled on two opposite sides of the cranial cavity using aseptic drilling technology, and the two sets of tube connectors are fixed at the hole positions using medical tape or sutures.

[0015] Preferably, the output ends of the main filter and the backup filter are both connected to a second pressure sensor, and the second pressure sensor is used to monitor the pressure of cerebrospinal fluid discharged from the output ends of the main filter and the backup filter.

[0016] Preferably, a second solenoid valve and a third solenoid valve are respectively provided on the pipeline connecting the second transmission pipeline to the main filter and the backup filter.

[0017] Preferably, a first pressure sensor is provided on the pump inlet pipe and the pump out pipe, and the first pressure sensor is used to monitor the pressure of cerebrospinal fluid in and out of the cranial cavity.

[0018] Preferably, the third storage bag is further provided with a waste discharge pipe, and the waste discharge pipe is provided with a fourth solenoid valve.

[0019] Preferably, the output ends of the main filter, the backup filter, the second storage bag, and the first storage bag are provided with first solenoid valves.

[0020] Preferably, the main filter and the backup filter both include a filter housing, a filter membrane is provided inside the filter housing, the filter membrane is provided with multiple pieces, the multiple filter membranes are stacked up and down, and a liquid inlet gap is left between adjacent filter membranes, a rectangular sealing plate is fixedly provided at the same end of the multiple filter membranes, a plurality of second elastic silicone sheets are fixedly provided on the periphery of the rectangular sealing plate, the second elastic silicone sheet is fixedly connected to the inner wall of the filter housing, a rectangular frame is fixedly provided on the other end of the multiple filter membranes, a first elastic silicone sheet is fixedly provided on the periphery of the rectangular frame, the first elastic silicone sheet is fixed on the inner wall of the filter housing, and multiple second elastic silicone sheets are fixedly provided on the inner wall of the filter housing. A flow groove is left between the two elastic silicone sheets; an outer chamber is formed between the outer periphery of the filter membrane and the inner wall of the filter housing, a discharge chamber is formed between the side of the rectangular sealing plate away from the filter membrane and the inner wall of the filter housing, an entry chamber is formed between the side of the rectangular frame away from the filter membrane and the inner wall of the filter housing, the entry chamber is connected to the second transmission pipeline through an entry port, the entry port is provided on the filter housing, a debris removal port is provided at the lower end of the entry chamber, the debris removal port is connected to the third storage bag, the entry chamber is connected to the liquid inlet gap, the outer chamber and the discharge chamber are connected through a flow groove, and the discharge chamber is connected to the second storage bag.

[0021] Preferably, the filter membrane is inclined toward the impurity removal port at one end close to the second transmission pipe.

[0022] Preferably, a force-bearing sphere is fixedly provided on one side of the rectangular frame close to the second transmission pipe, a rotating rod is rotatably provided on the inner wall of the filter housing, a rotating plate is fixedly provided on the rotating rod, the end of the rotating plate is arc-shaped, and the rotating plate is distributed correspondingly to the force-bearing sphere.

[0023] Preferably, the defoamer includes a defoamer shell, and a partition is vertically arranged inside the defoamer shell, which divides the interior of the defoamer shell into a second chamber and a first chamber. The first chamber is connected to the first transmission pipe, and the second chamber is connected to the pumping pipe. A connecting hole connecting the second chamber and the first chamber is provided on the partition, and a quantity and pressure control electronic valve is also installed on the connecting hole. A vacuum pump for evacuating the interior of the first chamber is provided on the defoamer shell.

[0024] Technical effects and advantages of the present invention:

[0025] 1. This method uses a circulating replacement method to filter cerebrospinal fluid, ensuring the stability of intracranial pressure, providing a basic guarantee for the normal input and discharge of cerebrospinal fluid, optimizing the environment within the cranial cavity, and replacing the method of directly replacing artificial cerebrospinal fluid. Only a small amount of artificial cerebrospinal fluid remains in the cranial cavity, which will not affect the balance of cerebrospinal fluid components and is more suitable for different populations;

[0026] 2. The pump-in replacement system and the pump-out replacement system of the present invention are integrated and cannot be disassembled, which meets the requirements of clinical disposable use. There is no need for temporary assembly of pipelines, which effectively improves the reliability of operation and avoids the contamination of temporary assembly interfaces.

[0027] 3. Since the filter membrane is provided with multiple pieces, instead of the traditional single-piece filter membrane, the purified cerebrospinal fluid is filtered out from the side holes of the filter membrane, which is less likely to cause filter membrane clogging. The filter core is composed of multiple strands of parallel and densely arranged filter membranes, thereby increasing the filtration area in a smaller cavity and minimizing the volume of the filter housing, meeting clinical use requirements;

[0028] 4. When the cerebrospinal fluid passes through the rectangular frame, it pushes the rotating plate to rotate. The rotating plate hits the force-bearing sphere, causing the filter membrane to vibrate, which can further discharge the bacteria and blood cells collected in the liquid inlet gap to avoid blockage.

[0029] 5. The vacuum pump is used to evacuate the first chamber in real time, so that all bubbles in the cerebrospinal fluid can be discharged, avoiding the problem of bubbles adhering to the inner wall of the first chamber and being unable to be discharged. The cerebrospinal fluid after the bubbles are removed is filled into the second chamber at an appropriate speed, enters the pump pipe, and is then supplied to the cranial cavity, so that the pressure of the cerebrospinal fluid entering the cranial cavity is restored;

[0030] 6. The filter membrane of the present invention uses a polyethersulfone hollow fiber membrane, etc., and the bacteria and blood cells blocked by the hollow fiber membrane will be carried away by the cerebrospinal fluid flowing in the membrane. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 It is a structural schematic diagram of the cerebrospinal fluid replacement and purification device of the present invention.

[0032] Figure 2 It is a schematic structural diagram of the main filter of the present invention.

[0033] Figure 3 It is a schematic structural diagram of the defoamer of the present invention.

[0034] Figure 4 Schematic diagram of the filter membrane structure of the present invention.

[0035] Figure 5 It is a schematic structural diagram of the rectangular frame and the rotating rod of the present invention when they cooperate with each other.

[0036] Figure 6 This is a cross-sectional view of the filter membrane of the present invention.

[0037] Figure 7 For the present invention Figure 5 A magnified schematic diagram of the structure in the middle.

[0038] In the figure: 1, pipe connector; 2, pump inlet pipe; 3, pump outlet pipe; 4, first storage bag; 5, first liquid pump; 6, first transmission pipe; 7, defoamer; 8, first pressure sensor; 9, second liquid pump; 10, main filter; 11, third storage bag; 12, second storage bag; 13, first solenoid valve; 14, return pipe; 15, second solenoid valve; 16, third solenoid valve; 17, second transmission pipe; 18, spare filter; 19, second pressure sensor; 20, one-way valve; 21, drainage pipe; 22, first Four solenoid valves; 23. Filter housing; 24. Rectangular frame; 25. Filter membrane; 26. Rectangular sealing plate; 27. First elastic silicone sheet; 28. Second elastic silicone sheet; 29. Peripheral chamber; 30. Exhaust chamber; 31. Inlet chamber; 32. Inlet port; 33. De-impurity port; 34. Defoamer housing; 35. Partition; 36. First chamber; 37. Second chamber; 38. Vacuum pump; 39. Connecting hole; 40. Quantity and pressure control electronic valve; 41. Circulation slot; 42. Rotating rod; 43. Rotating plate; 44. Force-bearing sphere. DETAILED DESCRIPTION

[0039] The present invention provides Figure 1-Figure 7 The cerebrospinal fluid replacement and purification device shown in the present invention can achieve the purpose of filtering and purifying cerebrospinal fluid, and can ensure the stability of intracranial pressure during the replacement process.

[0040] refer to Figure 1 As shown in , the cerebrospinal fluid replacement and purification device includes two major systems: a pump-in replacement system and a pump-out replacement system.

[0041] Among them, the pumping replacement system includes a first liquid pump 5 and a first storage bag 4. The first storage bag 4 is used to store artificial cerebrospinal fluid. When the first liquid pump 5 is started, the artificial cerebrospinal fluid stored in the first storage bag 4 can be pumped out. The first storage bag 4 is connected to the input end of the first liquid pump 5, and the output end of the first liquid pump 5 is connected to the first transmission pipe 6. The first transmission pipe 6 is connected to the input end of the defoamer 7. The defoamer 7 is used to eliminate bubbles in the cerebrospinal fluid so that the cerebrospinal fluid entering the cranial cavity does not contain bubbles and is safer. The output end of the defoamer 7 is provided with a pumping pipe 2, and the end of the pumping pipe 2 is connected to a pipeline connector 1.

[0042] When performing surgery on a patient, holes leading into the cranial cavity are first drilled on two opposite sides of the cranial cavity using sterile drilling technology, and the tube connector 1 is fixed at the hole position using medical tape or sutures. The tube connector 1 is also arranged in the same way on the other side of the cranial cavity, and the tube connector 1 on the other side of the cranial cavity is connected to the pump-out replacement system.

[0043] Among them, the pumping replacement system includes a second liquid pump 9, a second storage bag 12 and a third storage bag 11. The input end of the second liquid pump 9 is connected to a pumping pipe 3, and the pumping pipe 3 is connected to the corresponding pipe connector 1. When the second liquid pump 9 is started, the cerebrospinal fluid in the cranial cavity can be pumped out. The replacement method of pumping out the cerebrospinal fluid in the cranial cavity while pumping artificial cerebrospinal fluid into the cranial cavity ensures that the cerebrospinal fluid pressure in the cranial cavity is stable, and the intracranial pressure will not be too high or too low, which will damage the brain tissue.

[0044] The output end of the second liquid pump 9 is connected to a second transmission pipe 17. The second transmission pipe 17 is a three-way pipe. The other ends of the second transmission pipe 17 are respectively connected to the main filter 10 and the backup filter 18. The cerebrospinal fluid passing through the second transmission pipe 17 can be filtered by the main filter 10 and the backup filter 18 to remove pathogens and blood cells. The output ends of the main filter 10 and the backup filter 18 are both connected to the input end of the second storage bag 12 and the input end of the third storage bag 11. After the cerebrospinal fluid is filtered by the main filter 10 or the backup filter 18, clean cerebrospinal fluid, pathogens, and blood cells are formed. The clean cerebrospinal fluid is collected into the second storage bag 12, and the pathogens and blood cells are collected into the third storage bag 11. The output end of the second storage bag 12 is connected to a return pipe 14. The return pipe 14 is connected to the first liquid pump 5. The first liquid pump 5 can continue to pump the clean cerebrospinal fluid in the second storage bag 12 into the cranial cavity, so that the artificial cerebrospinal fluid in the cranial cavity is discharged and the clean cerebrospinal fluid is replaced with the clean cerebrospinal fluid.

[0045] This method uses a cyclic replacement method to filter cerebrospinal fluid, ensuring the stability of intracranial pressure, providing a basic guarantee for the normal input and discharge of cerebrospinal fluid, optimizing the environment within the cranial cavity, and replacing the method of directly replacing artificial cerebrospinal fluid. Only a small amount of artificial cerebrospinal fluid remains in the cranial cavity, which will not affect the composition balance of cerebrospinal fluid and is more suitable for different populations.

[0046] Furthermore, in the present invention, a second pressure sensor 19 is connected to the output ends of the main filter 10 and the backup filter 18. The second pressure sensor 19 is used to monitor the pressure of cerebrospinal fluid discharged from the output ends of the main filter 10 and the backup filter 18. If the pressure is too low, it proves that there is blockage inside the main filter 10 and the backup filter 18. In order to uninterrupted the surgical process, the corresponding solenoid valve can be opened and the main filter 10 and the backup filter 18 can be used alternately.

[0047] A second solenoid valve 15 and a third solenoid valve 16 are respectively provided on the pipeline connecting the second transmission pipeline 17 to the main filter 10 and the backup filter 18, which are used to control the on and off of the second transmission pipeline 17 so that cerebrospinal fluid enters the main filter 10 or the backup filter 18. The use can be intelligently adjusted according to the actual blockage situation.

[0048] It should also be noted that a first pressure sensor 8 is also provided on the pump-in pipe 2 and the pump-out pipe 3. The first pressure sensor 8 is used to monitor the pressure of cerebrospinal fluid in and out of the cranial cavity. If the pressure of cerebrospinal fluid pumped into the cranial cavity is low, the power of the first liquid pump 5 can be increased to increase the pumping power; if the pressure of cerebrospinal fluid pumped out of the cranial cavity is high, the power of the second liquid pump 9 can be increased to quickly discharge the high-pressure cerebrospinal fluid in the cranial cavity and avoid excessive pressure of cerebrospinal fluid in the cranial cavity; it can be intelligently adjusted according to actual needs, reducing the difficulty of surgery.

[0049] Furthermore, a drain pipe 21 is provided on the third storage bag 11, and a fourth solenoid valve 22 is provided on the drain pipe 21. When the fourth solenoid valve 22 is opened, the waste liquid in the third storage bag 11 can be discharged to avoid excessive pressure in the entire pipeline system, thereby achieving the purpose of rapid pressure reduction.

[0050] Correspondingly, a first solenoid valve 13 is provided at the output end of the main filter 10, the backup filter 18, the output end of the second storage bag 12, and the output end of the first storage bag 4 to facilitate control of the flow direction of cerebrospinal fluid in the entire pipeline. A one-way valve 20 is also provided at the output end of the main filter 10 and the backup filter 18 to prevent cerebrospinal fluid from flowing back. This is a common existing technology and will not be described in detail here.

[0051] The pump-in replacement system and the pump-out replacement system of the present invention are integrated and cannot be disassembled, which meets the requirements of clinical disposable use. There is no need for temporary assembly of pipelines, which effectively improves the reliability of operation and avoids the contamination of temporary assembly interfaces.

[0052] refer to Figure 2 、 Figures 4 to 7As shown in the figure, the main filter 10 and the spare filter 18 have the same internal and external structures, specifically including a filter housing 23, a filter membrane 25 is provided inside the filter housing 23, and the filter membrane 25 is provided with multiple pieces. The multiple filter membranes 25 are stacked up and down, and there is a liquid inlet gap between adjacent filter membranes 25. A rectangular sealing plate 26 is fixedly provided at the same end of the multiple filter membranes 25, and a plurality of second elastic silicone sheets 28 are fixedly provided on the periphery of the rectangular sealing plate 26. The second elastic silicone sheet 28 is fixedly connected to the inner wall of the filter housing 23, and a rectangular frame 24 is fixedly provided on the other end of the multiple filter membranes 25. A first elastic silicone sheet 27 is fixed on the periphery of the rectangular frame 24. The first elastic silicone sheet 27 is fixed on the inner wall of the filter housing 23. A flow groove 41 is left between the films 28; the outer periphery of the filter membrane 25 and the inner wall of the filter housing 23 form an outer chamber 29, the side of the rectangular sealing plate 26 away from the filter membrane 25 and the inner wall of the filter housing 23 form a discharge chamber 30, and the side of the rectangular frame 24 away from the filter membrane 25 and the inner wall of the filter housing 23 form an entry chamber 31. The entry chamber 31 is connected to the second transmission pipe 17 through an entry port 32. The entry port 32 is provided on the filter housing 23. A debris removal port 33 is provided at the lower end of the entry chamber 31. The debris removal port 33 is connected to the third storage bag 11, and the entry chamber 31 is connected to the liquid inlet gap. The outer chamber 29 and the discharge chamber 30 are connected through a flow groove 41, and the discharge chamber 30 is connected to the second storage bag 12.

[0053] During operation, cerebrospinal fluid is discharged into the chamber 31 through the second transmission pipe 17, and then enters multiple liquid inlet gaps through the interior of the rectangular frame 24. Since the filter membrane 25 is provided with multiple pieces, instead of the traditional method of providing a single filter membrane, the purified cerebrospinal fluid is filtered out from the side holes of the filter membrane 25, and the filter membrane is not easily clogged. The filter core is composed of multiple strands of densely arranged parallel filter membranes 25, thereby increasing the filtration area in a smaller cavity, so that the volume of the filter housing 23 is minimized, meeting clinical use requirements.

[0054] In the present invention, the filter membrane 25 is also arranged at an angle, and one end of the filter membrane 25 close to the second transmission pipe 17 is inclined toward the impurity removal port 33, so that the pathogens and blood cells filtered out in the liquid inlet gap can slide along the filter membrane 25 to the impurity removal port 33, and then be collected in the third storage bag 11.

[0055] Furthermore, a force-bearing sphere 44 is fixedly provided on one side of the rectangular frame 24 close to the second transmission pipe 17, and a rotating rod 42 is rotatably provided on the inner wall of the filter housing 23. A rotating plate 43 is fixedly provided on the rotating rod 42. The end of the rotating plate 43 is arc-shaped. When the cerebrospinal fluid passes through the rectangular frame 24, it pushes the rotating plate 43 to rotate, and the rotating plate 43 hits the force-bearing sphere 44, causing the filter membrane 25 to vibrate, which can further discharge the pathogens and blood cells collected in the liquid inlet gap to avoid blockage.

[0056] refer to Figure 3 As shown in the figure, the defoamer 7 includes a defoamer shell 34, and a partition 35 is vertically arranged inside the defoamer shell 34. The partition 35 divides the interior of the defoamer shell 34 into a second chamber 37 and a first chamber 36. The first chamber 36 is connected to the first transmission pipe 6, and the second chamber 37 is connected to the pump-in pipe 2. A connecting hole 39 is provided on the partition 35 to connect the second chamber 37 and the first chamber 36. A quantity and pressure control electronic valve 40 is also installed on the connecting hole 39. A vacuum pump 38 for evacuating the interior of the first chamber 36 is provided on the defoamer shell 34. When cerebrospinal fluid enters the second chamber 36 through the first transmission pipe 6, the cerebrospinal fluid is discharged from the second chamber 37. When in a chamber 36, the interior of the first chamber 36 is evacuated in real time by the vacuum pump 38, thereby reducing the air pressure in the first chamber 36, causing the bubbles in the cerebrospinal fluid to expand and escape under a lower air pressure. Because the first chamber 36 is evacuated in real time by the vacuum pump 38, all bubbles in the cerebrospinal fluid can be discharged, avoiding the problem of bubbles adhering to the inner wall of the first chamber 36 and being unable to be discharged. Then, the quantity and pressure control electronic valve 40 is started, and the cerebrospinal fluid after the bubbles are removed is filled into the second chamber 37 at an appropriate speed and then enters the pumping pipe 2, and then supplied to the cranial cavity, so that the pressure of the cerebrospinal fluid entering the cranial cavity is restored.

[0057] It should be noted that the filter membrane 25 in the present invention uses a polyethersulfone hollow fiber membrane, etc., and its membrane pores are 80A° to 100A°. The bacteria and blood cells blocked by the hollow fiber membrane will be carried away by the cerebrospinal fluid flowing in the membrane.

Claims

1. A cerebrospinal fluid replacement and purification device, characterized in that: include: A pumping replacement system, comprising a first liquid pump (5) and a first storage bag (4), wherein the first storage bag (4) is used to store artificial cerebrospinal fluid, the first storage bag (4) is connected to the input end of the first liquid pump (5), the output end of the first liquid pump (5) is connected to a first transmission pipeline (6), the first transmission pipeline (6) is connected to the input end of a defoamer (7), the output end of the defoamer (7) is provided with a pumping pipeline (2), and the end of the pumping pipeline (2) is butt-jointed with a pipeline connector (1); When the first liquid pump (5) is started, the artificial cerebrospinal fluid stored in the first storage bag (4) is pumped out, and the defoamer (7) is used to eliminate bubbles in the cerebrospinal fluid; A pump-out replacement system, comprising a second liquid pump (9), a second storage bag (12) and a third storage bag (11); an input end of the second liquid pump (9) is connected to a pump-out pipe (3); the pump-out pipe (3) is connected to another set of pipeline connectors (1); an output end of the second liquid pump (9) is connected to a second transmission pipe (17); the second transmission pipe (17) is a three-way pipe; the other two ends of the second transmission pipe (17) are respectively connected to a main filter (10) and a spare filter (18); cerebrospinal fluid passing through the second transmission pipe (17) is filtered by the main filter (10) and the spare filter (18) to remove pathogens and blood cells; the output ends of the main filter (10) and the spare filter (18) are both connected to the input end of the second storage bag (12) and the input end of the third storage bag (11); the cerebrospinal fluid is filtered by the main filter (10) or the spare filter (18) to form clean cerebrospinal fluid, pathogens and blood cells; The clean cerebrospinal fluid is collected into the second storage bag (12), and the pathogens and blood cells are collected into the third storage bag (11); The output end of the second storage bag (12) is connected to a return pipe (14), which is connected to the first liquid pump (5), and the clean cerebrospinal fluid in the second storage bag (12) is continuously pumped into the cranial cavity through the first liquid pump (5); Holes leading to the cranial cavity are drilled on two opposite sides of the cranial cavity using a sterile drilling technique, and two sets of tube connectors (1) are fixed at the hole positions using medical tape or sutures.

2. The cerebrospinal fluid replacement and purification device according to claim 1, characterized in that: The output ends of the main filter (10) and the backup filter (18) are both connected to a second pressure sensor (19), and the second pressure sensor (19) is used to monitor the pressure of cerebrospinal fluid discharged from the output ends of the main filter (10) and the backup filter (18).

3. The cerebrospinal fluid replacement and purification device according to claim 1, characterized in that: A second solenoid valve (15) and a third solenoid valve (16) are respectively provided on the pipeline connecting the second transmission pipeline (17) to the main filter (10) and the backup filter (18).

4. The cerebrospinal fluid replacement and purification device according to claim 1, characterized in that: The pump inlet pipe (2) and the pump outlet pipe (3) are provided with a first pressure sensor (8), and the first pressure sensor (8) is used to monitor the pressure of cerebrospinal fluid in and out of the cranial cavity.

5. The cerebrospinal fluid replacement and purification device according to claim 1, characterized in that: The third storage bag (11) is further provided with a waste discharge pipe (21), and the waste discharge pipe (21) is provided with a fourth electromagnetic valve (22).

6. The cerebrospinal fluid replacement and purification device according to claim 1, characterized in that: The output ends of the main filter (10), the backup filter (18), the second storage bag (12), and the first storage bag (4) are provided with a first solenoid valve (13).

7. The cerebrospinal fluid replacement and purification device according to claim 1, characterized in that: The main filter (10) and the standby filter (18) both comprise a filter housing (23), a filter membrane (25) is provided inside the filter housing (23), a plurality of filter membranes (25) are provided, the plurality of filter membranes (25) are stacked and distributed up and down, and a liquid inlet gap is left between adjacent filter membranes (25), a rectangular sealing plate (26) is fixedly provided at the same end of the plurality of filter membranes (25), a plurality of second elastic silicone sheets (28) are fixedly provided on the periphery of the rectangular sealing plate (26), the second elastic silicone sheets (28) are fixedly connected to the inner wall of the filter housing (23), a rectangular frame (24) is fixedly provided at the other end of the plurality of filter membranes (25), a first elastic silicone sheet (27) is fixedly provided on the periphery of the rectangular frame (24), the first elastic silicone sheet (27) is fixed on the inner wall of the filter housing (23), and a flow groove (28) is left between the plurality of second elastic silicone sheets (28) 41); an outer chamber (29) is formed between the periphery of the filter membrane (25) and the inner wall of the filter housing (23); a discharge chamber (30) is formed between the side of the rectangular sealing plate (26) away from the filter membrane (25) and the inner wall of the filter housing (23); an entry chamber (31) is formed between the side of the rectangular frame (24) away from the filter membrane (25) and the inner wall of the filter housing (23); the entry chamber (31) is communicated with the second transmission pipe (17) through an entry port (32); the entry port (32) is provided on the filter housing (23); a de-impurity port (33) is provided at the lower end of the entry chamber (31); the de-impurity port (33) is communicated with the third storage bag (11); the entry chamber (31) is communicated with the liquid inlet gap; the outer chamber (29) and the discharge chamber (30) are communicated with the flow groove (41); and the discharge chamber (30) is communicated with the second storage bag (12).

8. The cerebrospinal fluid replacement and purification device according to claim 7, characterized in that: One end of the filter membrane (25) close to the second transmission pipe (17) is inclined toward the impurity removal port (33).

9. The cerebrospinal fluid replacement and purification device according to claim 7, characterized in that: A force-bearing sphere (44) is fixedly provided on one side of the rectangular frame (24) close to the second transmission pipe (17); a rotating rod (42) is rotatably provided on the inner wall of the filter housing (23); a rotating plate (43) is fixedly provided on the rotating rod (42); the end of the rotating plate (43) is arc-shaped; the rotating plate (43) and the force-bearing sphere (44) are distributed correspondingly.

10. The cerebrospinal fluid replacement and purification device according to claim 1, characterized in that: The defoamer (7) comprises a defoamer housing (34), a partition (35) is vertically arranged inside the defoamer housing (34), and the partition (35) divides the interior of the defoamer housing (34) into a second chamber (37) and a first chamber (36), the first chamber (36) is connected to the first transmission pipe (6), and the second chamber (37) is connected to the pumping pipe (2), and a connecting hole (39) is provided on the partition (35) and is connected between the second chamber (37) and the first chamber (36), and a quantity and pressure control electronic valve (40) is also installed on the connecting hole (39), and a vacuum pump (38) for evacuating the interior of the first chamber (36) is provided on the defoamer housing (34).

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