Needleless injection device for tumor drug injection and injection method thereof

Abstract

The invention discloses a needleless injection device for tumor drug injection and an injection method of the needleless injection device. The needleless injection device comprises an injection mechanism and an atomization mechanism arranged below the injection mechanism. The injection mechanism comprises an outer shell, a pushing assembly arranged on the inner side of the outer shell and a plurality of power sources arranged at the bottom of the outer shell. The power source is mainly used for providing power for the device. The pushing assembly is mainly used for pushing high-speed injection of medicine. The atomization mechanism comprises a medicine kettle, an atomization piece fixedly connected to the interior of the medicine kettle and a negative pressure piece arranged on one side of the atomization piece. The medicine pot is in threaded connection with the bottom of the outer shell, the negative-pressure part is arranged on the atomization part, and the bottom of the negative-pressure part is fixedly connected with a micromotor; therefore, the safety, the convenience and the comfort degree of medicine delivery are improved.

Description

Technical Field

[0001] The present invention relates to the field of tumor drug delivery, in particular to the field of needle-free injection delivery of tumor drugs, and more particularly to a needle-free injection device for tumor drug injection and an injection method thereof. Background Art

[0002] Common routes of administration of anti-tumor drugs include systemic administration, local administration, intrathecal administration, and intra-arterial injection. However, most of these injections are inconvenient for patients to operate, as well as a series of problems such as needle damage and cross infection. It is especially difficult to operate for some patients who are afraid of needles. Currently, needle-free injection can improve patient convenience, safety and injection efficiency, but unlicensed injection uses high-pressure injection. For some pressure-sensitive tumor drugs, needle-free injection will cause drug degradation or inactivation. Summary of the Invention

[0003] The present invention overcomes the deficiencies of the prior art and provides a needle-free injection device for tumor drug injection and an injection method thereof.

[0004] To achieve the above-mentioned object, the technical solution adopted by the present invention is: a needle-free injection device for tumor drug injection and an injection method thereof, comprising: an injection mechanism, and an atomization mechanism disposed below the injection mechanism:

[0005] The injection mechanism includes: an outer shell, a driving assembly disposed inside the outer shell, and a plurality of power supplies disposed at the bottom of the outer shell; the power supplies are mainly used to provide power to the device, and the driving assembly is mainly used to drive the high-speed ejection of the drug;

[0006] The atomization mechanism includes: a medicine pot, an atomization component fixedly connected to the inside of the medicine pot, and a negative pressure component arranged on one side of the atomization component; the medicine pot is threadedly connected to the bottom of the outer shell, and the negative pressure component is arranged on the atomization component.

[0007] In a preferred embodiment of the present invention, the outer shell is configured as a gun-like structure with a hollow inner side. A threaded groove is provided on the top of the outer shell for threaded connection with the gas tank. The outer shell includes an energy zone, a propulsion zone and an injection zone.

[0008] In a preferred embodiment of the present invention, the energy zone is arranged below the outer shell, and a placement groove is provided on the inner side of the energy zone. The placement groove is used to place the power supply, and a power supply cover is clamped on one side of the placement groove; the propulsion zone is arranged at the middle position above the outer shell and is hollow, and the pushing component is arranged at the hollow position of the propulsion zone; the injection zone is arranged at the front end of the outer shell and is provided with an iris mechanism that can seal the inside of the outer shell.

[0009] In a preferred embodiment of the present invention, the iris mechanism is provided with a long thin tube on one side inside the shell, and the iris mechanism is provided with a micro cylinder on one side. The micro cylinder is used to control the switch of the iris mechanism, and the iris mechanism is used to form a sealed space inside the outer shell to control the injection of the medicine.

[0010] In a preferred embodiment of the present invention, the pushing component is mainly composed of a hollow tube, two coil groups, a Hall sensor and a control panel. The hollow tube is arranged in the middle position of the outer shell, and a slider made of iron is slidably connected to the inner side thereof. The coil group is provided with two coils respectively sleeved on the two ends of the outer side of the hollow tube. The hollow tube and the threaded groove are connected and closed by a one-way valve. The hollow tube is made of ceramic material.

[0011] In a preferred embodiment of the present invention, a plurality of coils are provided in the coil group, a Hall sensor is provided in the middle position of the coil, a power supply, a control panel, a transistor, a coil group and a Hall sensor are electrically connected in sequence, and the two coil groups are respectively connected to the circuit.

[0012] In a preferred embodiment of the present invention, the atomizer is mainly composed of piezoelectric ceramics and a sponge strip. The sponge strip is fixedly connected to the bottom of the piezoelectric ceramics. The piezoelectric ceramics and the micromotor are electrically connected to the power supply through a control panel. A one-way valve is provided on the top of the medicine pot to control the connection and closing of the medicine pot and the hollow tube.

[0013] A method for needle-free injection of tumor drugs, comprising the following steps:

[0014] S1: Install the gas tank on the top of the outer shell and the medicine pot on the bottom of the outer shell;

[0015] S2: The medicine in the medicine pot is atomized by the atomizing element, and the atomized medicine is blown to the pot mouth by the negative pressure element;

[0016] S3: The driving component is controlled by the power supply to inhale the gas in the gas tank and the atomized medicine in the medicine pot into the outer shell;

[0017] S4: The power supply discharges again, pushing the component to push the medicine and gas out of the outer shell, so that the atomized medicine is quickly sprayed to form an air flow beam, which enters the human body through the skin or mucous membrane.

[0018] In a preferred embodiment of the present invention, in S3 and S4, the pushing component performs two actions, namely, sucking the gas inside the gas tank and pushing out the medicine through the electromagnetic field formed by the coil group. During the suction, only the coil group in the pushing component close to the medicine ejection end generates an electromagnetic field. During the ejection, the coil groups at both ends act simultaneously, and the electromagnetic field generated by the coil group far away from the medicine ejection end is greater than the electromagnetic field generated by the coil group at the other end.

[0019] In a preferred embodiment of the present invention, in S4, the injection speed of the medicine is 150m / s-300m / s.

[0020] The present invention solves the defects existing in the background technology and has the following beneficial effects:

[0021] (1) The present invention provides a needle-free injection device for tumor drug injection and an injection method thereof. By the mutual cooperation between the atomizer and the injection mechanism, the granular drug is atomized by the vibration of the piezoelectric ceramic in the atomizer, thereby reducing its particle size and increasing its contact area with the external environment. At the same time, the interaction force between its molecules is enhanced, avoiding the influence of shear force and impact force under pressure, which leads to degradation or inactivation of the drug. Compared with the drug delivery in the prior art, while ensuring the effectiveness of the drug, the safety, convenience and comfort of drug delivery are improved for patients.

[0022] (2) The present invention provides a needle-free injection device and injection method for tumor drug injection. By using the mutual cooperation between the coil group, the control panel and the slider, the two coil groups are energized and controlled separately by the control panel to generate electromagnetic fields at different stages, driving the slider to move back and forth quickly in the hollow tube, while completing the absorption and rapid discharge of the gas and atomized drugs in the high-pressure gas tank, completing the needle-free injection operation. Compared with the existing technology, the needle-free injection of pressure-sensitive tumor drugs is completed by the means of unlicensed injection.

[0023] (3) The present invention provides a needle-free injection device for tumor drug injection and an injection method thereof. By promoting the cooperation between the push component, the ceramic medicine pot and the ceramic hollow tube, the ceramic medicine pot and the hollow tube prevent the external temperature from entering the interior, thereby increasing the temperature of the atomized drug and accelerating the degradation of the drug. At the same time, the drug is always kept in a low-temperature environment. Compared with the prior art, the drug in the low-temperature environment of the device of the present application reduces its sensitivity to the pressure it is subjected to, ensures the stability and activity of the drug under the pressure of needle-free injection, and avoids the influence of shear force and impact force under pressure, which leads to degradation or inactivation of the drug.

[0024] (4) The present invention provides a needle-free injection device and injection method for tumor drug injection, which realizes liquid atomization by utilizing the piezoelectric effect through the mutual cooperation between the sponge strip and the piezoelectric ceramic. By applying a voltage signal, the piezoelectric ceramic sheet is deformed and mechanical stress is generated, thereby realizing the atomization operation of the drug, so that the drug is atomized into a small liquid particle, thereby reducing the distance between the drug particles, the interaction force between molecules is stronger, and it can better resist the influence of shear force and impact force, reduce the degradation and inactivation of the drug, and at the same time, reducing the particle size of the drug can also increase the surface area of the drug, making the drug easier to contact with the surrounding environment, improving the solubility and absorption rate of the drug, and further improving the stability and effect of the drug. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments described in the present invention. Those skilled in the art can also derive other drawings based on these drawings without inventive efforts.

[0026] Figure 1 It is a three-dimensional structural diagram of a preferred embodiment of the present invention;

[0027] Figure 2 It is a preferred embodiment of the present invention;

[0028] In the picture:

[0029] 1. Injection mechanism; 10. Outer shell; 11. Push assembly; 12. Energy zone; 13. Propulsion zone; 14. Injection zone; 15. Iris mechanism; 16. Long thin tube; 17. Hollow tube; 18. Coil assembly

[0030] 2. Atomization mechanism; 20. Medicine pot. DETAILED DESCRIPTION

[0031] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0032] In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the scope of protection of the present invention is not limited to the specific embodiments disclosed below.

[0033] In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the scope of protection of the present application. In addition, the terms "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, features defined as "first", "second", etc. may explicitly or implicitly include one or more of the features. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0034] In the description of this application, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; and they can refer to internal connections between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on specific circumstances.

[0035] like Figure 1 and Figure 2 As shown, a needle-free injection device for tumor drug injection and an injection method thereof include: an injection mechanism 1, and an atomization mechanism 2 arranged below the injection mechanism 1.

[0036] It should be noted that some tumor-targeted radiotherapy drugs may be sensitive to pressure, including protein kinase inhibitors: Some tumor-targeted therapy drugs are protein kinase inhibitors, such as erlotinib and gefitinib. These drugs are usually administered orally in tablets or capsules, but when used in needle-free injection, the drug molecules may be damaged or decomposed due to the effect of high-pressure airflow, resulting in drug inactivation; similar drugs are also in this category: antibody drugs are a class of drugs commonly used in tumor-targeted therapy, such as pertuzumab and trastuzumab. These drugs are usually administered by intravenous injection, but when used in needle-free injection, the antibody structure of the drug may change due to the effect of high-pressure airflow, resulting in inactivation or aggregation of the drug; therefore, we first perform atomization operation on the drug using a practical atomization mechanism 2, and then use the injection mechanism 1 for needle-free injection. Before both operations are performed, the drugs are stored at low temperatures. The hollow tube and medicine pot in the device of this application are made of ceramic material. Ceramics have good insulation properties, so that the external high temperature will not be transmitted into the medicine pot, thereby keeping the internal temperature at a lower temperature at all times.

[0037] The injection mechanism 1 includes: an outer shell 10, a push assembly 11 disposed inside the outer shell 10, and a plurality of power supplies disposed at the bottom of the outer shell 10; the power supply is mainly used to provide power to the device, and the push assembly 11 is mainly used to promote the high-speed injection of the drug;

[0038] In a preferred embodiment of the present invention, the outer shell 10 is configured as a gun-like structure with a hollow inner side. A threaded groove is provided on the top of the outer shell 10 for threaded connection with the gas tank. The outer shell 10 includes an energy zone 12, a propulsion zone 13 and an injection zone 14.

[0039] In a preferred embodiment of the present invention, the energy zone 12 is arranged below the outer shell 10, and a placement groove is provided on the inner side of the energy zone 12. The placement groove is used to place the power supply, and a power supply cover is clamped on one side of the placement groove; the propulsion zone 13 is arranged in the middle position above the outer shell 10 and is hollow, and the pushing component 11 is arranged at the hollow position of the propulsion zone 13; the injection zone 14 is arranged at the front end of the outer shell 10 and is provided with an iris mechanism 15 that can seal the interior of the outer shell 10.

[0040] It should be noted that the outer shell 10 is an L-shaped gun body structure as a whole. The handle below the outer shell 10 is the energy zone 12, which is mainly used to place the power supply. The upper part of the handle is arranged horizontally, and its front end outlet is the injection zone 14. The injection zone 14 is mainly used to spray the medicine in the form of a wire bundle from the inside of the gun body. The injection zone 14 is provided with an iris mechanism 15 for controlling the opening and closing of the injection zone 14. The iris mechanism 15 is sealed, and the propulsion zone 13 is between the rear end of the injection zone 14 and the handle, that is, the energy zone 12. A threaded hole is provided at the top of the outer shell 10 of the propulsion zone 13. The threaded hole is threadedly connected to the high-pressure gas tank, and a one-way valve is provided on the inside of the threaded hole. The direction of the one-way valve can only allow the gas in the high-pressure gas tank to enter the interior of the outer shell 10, but not to be discharged.

[0041] In a preferred embodiment of the present invention, the iris mechanism 15 is provided with a long thin tube 16 on one side inside the shell, and the iris mechanism 15 is provided with a micro cylinder on one side. The micro cylinder is used to control the switch of the iris mechanism 15, and the iris mechanism 15 is used to form a sealed space inside the outer shell 10 to control the injection of the drug.

[0042] It should be noted that the iris mechanism 15 is mainly composed of a fixed plate, a rotating ring, a transmission shaft and several opening plates; a through hole is opened in the middle position of the rotating plate, the rotating ring is rotatably connected to the fixed plate, the fixed plate is fixedly connected to the inner side of the outer shell 10, the rotating ring is fixedly connected to the micro cylinder, one end of the rotating shaft is rotatably connected to the rotating ring, and the other end is rotatably connected to the opening plate. The opening plate is similar to the Leclerc triangle design, but the difference is that the Leclerc triangle is three times arranged in an outward arc shape, while one side of the opening plate is recessed inwardly. The other two sides of the opening plate except the bottom side are arranged in an arc shape convex outwardly, while the other side is arranged in an arc shape concave inwardly. A protruding fitting block is provided between the inwardly concave sides, and a fitting groove is provided on the protruding arc side, and the fitting groove and the fitting block can engage with each other. The top of the opening plate is arranged at the center of the circular through hole of the fixed plate, and the two end points of the bottom are located on the circumference of the through hole, one end point is rotatably connected to the bottom plate, and the other end point is rotatably connected to the transmission shaft.

[0043] Therefore, when working, the contraction of the micro cylinder drives the rotating ring to rotate on the rotating plate, thereby driving the transmission shaft to deflect, so that the transmission shaft drives the opening plate to rotate at the rotating connection point between the opening plate and the fixed plate, so that the fitting block and the fitting groove are engaged, and the fitting block and the fitting groove are interference fit, thereby achieving sealing of the through hole on the fixed plate. A long thin tube 16 is provided on the inner side of the outer shell 10, and the long thin tube 16 is provided at the center of the through hole of the fixed plate, and the long thin tube 16 is sealed with the opening plate, and the inner diameter of the long thin tube 16 is 0.1 mm-0.3 mm.

[0044] In a preferred embodiment of the present invention, the pushing component 11 is mainly composed of a hollow tube 17, two coil groups 18, a Hall sensor and a control panel. The hollow tube 17 is arranged in the middle position of the outer shell 10, and a slider made of iron is slidably connected to the inner side thereof. The coil group 18 is provided with two coils respectively sleeved on the two ends of the outer side of the hollow tube 17. The hollow tube 17 and the threaded groove are connected and closed by a one-way valve. The hollow tube is made of ceramic material.

[0045] In a preferred embodiment of the present invention, a plurality of coils are provided in the coil group 18, and a Hall sensor is provided in the middle of the coils. The power supply, the control panel, the transistor, the coil group 18 and the Hall sensor are electrically connected in sequence, and the two coil groups 18 are respectively connected to the circuit.

[0046] It should be noted that the hollow tube 17 is arranged in the middle position of the outer shell 10, the rear end of which is in a sealed state, and the front end is fixedly connected to the long thin tube 16, which is also sealed. The top of the hollow tube 17 is fixedly connected to the one-way valve, so that the gas in the high-pressure gas tank can enter the hollow tube 17 through the one-way valve, and the bottom is threadedly connected to the medicine pot 20 at the bottom of the outer shell 10. The iron slider is slidably connected to the inside of the hollow tube 17. There are two coil groups 18 respectively arranged at both ends of the hollow tube 17. Each coil group 18 is provided with a number of coils. Based on Faraday's law of electromagnetic induction and Lorentz force law, when the coil is energized, the coil A magnetic field is generated around the coil, and the generated magnetic field will attract the metal iron slider. That is, according to Fleming's left-hand rule, the magnetic field generates an Ampere force on the metal slider to push it to move, so that the slider obtains an initial speed and moves quickly toward the coil. When the slider slides to the middle of the coil, the slider speed reaches the maximum. When the slider slides to the other end of the coil due to inertia and the attraction of the magnetic field, the slider is attracted by the attraction and slides back due to the action of the magnetic field. The hollow tube is made of ceramic material with low thermal conductivity, which can effectively prevent the heat generated by the electromagnetic field from being transmitted into the hollow tube, causing the temperature of the drug to rise faster and degrade faster.

[0047] The Hall effect sensor is located near the center of each coil and typically consists of a Hall element, an amplifier, and an output interface. A Hall effect element is a semiconductor device with electrodes and a Hall effect sensing area. When a magnetic field acts on the Hall effect element, the charge distribution within the sensing area changes, generating a voltage difference. The amplifier amplifies the weak signal output by the Hall effect element to enable accurate measurement, and the output interface transmits the amplified signal to the controller. The Hall effect sensor is located in the center of the coil. The moment the Hall effect sensor senses the slider, it sends a signal to the control panel, which uses a transistor to de-energize the coil at that location. As a result, the slider relies on inertia to slide out of the magnetic field of that coil at that speed and enter the magnetic field of the next coil.

[0048] A triode, also known as a transistor, is a common electronic device used to amplify and switch electrical signals. Its operating principle is based on the properties of semiconductor materials. In an NPN triode, the emitter and base are P-type semiconductors, while the collector is an N-type semiconductor. When a small current (called the base current) is applied between the base and emitter, a large current (called the collector current) changes between the emitter and collector. When the base current is zero, the collector current is also zero, and the triode is in the off state. When the base current increases sufficiently, the collector current becomes very large, and the triode is in the on state. Switching mode is often used in digital circuits and logic gate circuits.

[0049] The power supply is provided with several groups, which form two circuits with the control panel and the transistor respectively. The two coil groups 18 are connected in series in the two circuits and are controlled by the control panel. The Hall sensor is connected to the coil, and the current directions in the two circuits are opposite.

[0050] During operation, the control panel controls the power supply to energize the circuits respectively. When it is necessary to absorb the gas in the high-pressure gas tank, the coil group 18 near the long thin tube 16 is energized, so that a magnetic field is generated in the coil group 18, and an Ampere force is generated on the slider in the direction away from the long thin tube 16, pushing the slider to the end of the hollow tube 17, that is, the end away from the long thin tube 16. Since the long thin tube 16 and the hollow tube 17 are connected and sealed, the gas in the high-pressure gas tank above and the atomized medicine at the bottom are absorbed into the hollow tube 17 through the one-way valve. After that, when injecting, the control panel energizes the other coil group 18, and since the current directions of the two coil groups 18 are opposite, the Ampere forces generated by them are in opposite directions, which produces a deceleration effect on the slider to prevent the slider from being hit by excessive inertia and damaging the equipment after long-term use.

[0051] The atomization mechanism 2 includes: a medicine pot 20, an atomizing component fixedly connected to the inside of the medicine pot 20, and a negative pressure component arranged on one side of the atomizing component; the medicine pot 20 is threadedly connected to the bottom of the outer shell 10, and the negative pressure component is arranged on the atomizing component; a one-way valve is provided on the top of the medicine pot 20 for controlling the connection and closing of the medicine pot 20 and the hollow tube 17.

[0052] In a preferred embodiment of the present invention, the atomizer is mainly composed of piezoelectric ceramics and a sponge strip, the sponge strip is fixedly connected to the bottom of the piezoelectric ceramics, and the piezoelectric ceramics and the micromotor are electrically connected to the power supply through the control panel.

[0053] It should be noted that piezoelectric ceramic atomizers utilize the piezoelectric effect to atomize liquids. Applying a voltage signal causes the piezoelectric ceramic to deform, generating mechanical stress and thus atomizing the liquid. Controlling the amplitude and frequency of the applied voltage signal can adjust the atomized particle size; the negative pressure element can...

[0054] A piezoelectric ceramic atomizer typically consists of two components: a piezoelectric ceramic disc and a spray orifice. The piezoelectric ceramic disc is the core component of the entire atomizer. It is connected to an external power source via electrodes, generating an electric field. When voltage is applied, the electric field acts on the piezoelectric ceramic disc, causing it to deform. This deformation is transmitted to the spray orifice, causing it to vibrate. The spray orifice is a thin plate located above the piezoelectric ceramic disc and has numerous tiny holes. When the piezoelectric ceramic disc vibrates, the spray orifice vibrates with it, causing a thin film of liquid to form around the holes. As the vibration intensifies, the liquid film gradually breaks down, forming tiny droplets that are ejected outward as the spray orifice vibrates. By adjusting the magnitude and frequency of the external voltage, the vibration characteristics of the piezoelectric ceramic disc can be controlled, thereby adjusting the size and volume of the spray particles. The rotation of the piezoelectric ceramic disc disperses the fluid into tiny droplets, which are then dispersed through the airflow into a fine spray, thereby reducing the particle size of the drug.

[0055] During operation, the medicine pot 20 is threadedly connected to the bottom of the outer shell 10; the atomizer is fixedly connected to the inner side of the medicine pot 20, and the negative pressure part is rotatably connected to the inner side of the medicine pot 20. The negative pressure part is arranged at the bottom of the atomizer and is driven by a micromotor. During operation, the atomizer atomizes the medicine. The negative pressure part is mainly used to make the upper part of the medicine pot exceed the negative pressure, thereby drawing the atomized medicine upward. Preferably, it is through a combination of a micromotor and a fan blade, the fan blade is rotatably connected to the upper part of the medicine pot, and the fan blade is driven by a micromotor. The micromotor is fixedly connected to the medicine pot, and the combination of the fan blade and the micromotor is arranged on one side of the pressed ceramic. By creating a pressure difference between the upper and lower sides of the fan blade, the air inside the medicine pot surges upward without affecting the rise of the medicine. The water mist medicine atomized by the atomizer is blown into the hollow tube 17 through the negative pressure part. The medicine pot is also made of ceramic material. The medicine is always preserved by a low-temperature preservation method, which effectively ensures the effectiveness of the medicine and reduces its sensitivity to pressure.

[0056] A method for needle-free injection of tumor drugs, comprising the following steps:

[0057] S1: Install the gas tank on the top of the outer shell and the medicine pot on the bottom of the outer shell;

[0058] S2: The medicine in the medicine pot is atomized by the atomizing element, and the atomized medicine is blown to the pot mouth by the negative pressure element;

[0059] S3: The power control push component sucks the gas in the gas tank into the outer shell, and then opens the mouth of the medicine pot, and the atomized medicine gradually rises into the inner side of the outer shell;

[0060] S4: The power supply discharges again, pushing the component to push the medicine and gas out of the outer shell, so that the atomized medicine is quickly sprayed to form an air flow beam, which enters the human body through the skin or mucous membrane.

[0061] In a preferred embodiment of the present invention, in S3 and S4, the pushing component 11 performs two actions of absorbing the gas inside the gas tank and pushing out the medicine respectively through the electromagnetic field formed by the coil group 18. During the absorption, only the coil group 18 close to the medicine ejection end in the pushing component 11 generates an electromagnetic field. During the ejection, the coil groups 18 at both ends act simultaneously, and the electromagnetic field generated by the coil group 18 far away from the medicine ejection end is greater than the electromagnetic field generated by the coil group 18 at the other end.

[0062] In a preferred embodiment of the present invention, in S4, the injection speed of the medicine is 150m / s-300m / s. When the present invention is used, the high-pressure gas tank is installed at the threaded hole above the outer shell 10, and the medicine pot 20 is installed at the bottom of the outer shell 10. The control panel controls the slider to move back and forth in the hollow tube 17. The end of the hollow tube 17 close to the injection area 14 is the front end, and the other end is the rear end. When injecting, the iris mechanism 15 is controlled by the micro cylinder to open the atomizer in the medicine pot 20 to atomize the medicine. The control panel energizes the coil group 18 at the rear end, thereby pushing the slider to move to the front end of the hollow tube 17. , the air inside the hollow tube 17 is discharged, and the iris mechanism 15 is closed through the micro cylinder. Then the control panel energizes the front coil group 18, so that the slider moves to the rear end of the hollow tube 17. At the same time, the gas and medicine in the high-pressure gas tank are absorbed through the one-way valve and absorbed into the hollow tube 17. At this time, the iris mechanism 15 is opened again, and then the control panel quickly pushes the slider through the Ampere force generated by the rear coil group 18, so that the medicine and gas quickly enter the long and thin tube 16. Since the aperture of the long and thin tube 16 is 0.1-0.3 mm, the atomized medicine and gas form a bundle shape, which is quickly sprayed out and injected into the human body.

[0063] The above description is based on the ideal embodiment of the present invention. Based on the above description, relevant personnel can make various changes and modifications without departing from the technical scope of this invention. The technical scope of this invention is not limited to the content of the specification and must be determined according to the scope of the claims.

Claims

1. A needle-free injection device for tumor drug injection, comprising: The injection mechanism and the atomization mechanism arranged below the injection mechanism are characterized by: The injection mechanism includes: an outer shell, a pushing assembly disposed inside the outer shell, and a plurality of power supplies disposed at the bottom of the outer shell; the power supplies are mainly used to provide power to the device, and the pushing assembly is mainly used to push the drug to be ejected at high speed; The atomization mechanism includes: a medicine pot, an atomization component fixedly connected to the inside of the medicine pot, and a negative pressure component arranged on one side of the atomization component; the medicine pot is threadedly connected to the bottom of the outer shell, and the negative pressure component is rotatably connected to the atomization component.

2. The needle-free injection device for tumor drug injection according to claim 1, characterized in that: The outer shell is configured as a gun-like structure with a hollow inner side. A threaded groove is provided on the top of the outer shell to be threadedly connected to the gas tank. The outer shell includes an energy area, a propulsion area, and a spray area.

3. The needle-free injection device for tumor drug injection according to claim 2, characterized in that: The energy zone is arranged below the outer shell, and a placement groove is arranged inside the energy zone. The placement groove is used to place the power supply, and a power supply cover is clamped on one side of the placement groove; the propulsion zone is arranged at the middle position above the outer shell and is hollow, and the pushing component is arranged at the hollow position of the propulsion zone; the injection zone is arranged at the front end of the outer shell and is provided with an iris mechanism that can seal the inside of the outer shell.

4. The needle-free injection device for tumor drug injection according to claim 3, characterized in that: The iris mechanism is provided with a long thin tube on one side inside the shell, and the iris mechanism is provided with a micro cylinder on one side. The micro cylinder is used to control the switch of the iris mechanism, and the iris mechanism is used to form a sealed space inside the outer shell to control the injection of medicine.

5. The needle-free injection device for tumor drug injection according to claim 1, characterized in that: The pushing component is mainly composed of a hollow tube, two coil groups, a Hall sensor and a control panel. The hollow tube is arranged in the middle position of the outer shell, and a slider made of iron is slidably connected to the inner side of the hollow tube. The coil group is provided with two coils respectively sleeved on the two ends of the outer side of the hollow tube. The hollow tube and the threaded groove are connected and closed by a one-way valve.

6. The needle-free injection device for tumor drug injection according to claim 5, characterized in that: Several coils are arranged in the coil group, and the Hall sensor is arranged in the middle of the coil. The power supply, the control panel, the transistor, the coil group and the Hall sensor are electrically connected in sequence, and the two coil groups are respectively connected to the circuit.

7. The needle-free injection device for tumor drug injection according to claim 1, characterized in that: The atomizer is mainly composed of piezoelectric ceramics and a sponge strip. The sponge strip is fixedly connected to the bottom of the piezoelectric ceramics. The piezoelectric ceramics and the micromotor are electrically connected to the power supply through a control panel. A one-way valve is provided on the top of the medicine pot to control the connection and closing of the medicine pot and the hollow tube.

8. An injection method for needle-free injection of tumor drugs, based on the injection method of the needle-free injection device according to claims 1-7, characterized in that: Follow these steps: S1: Install the gas tank on the top of the outer shell and the medicine pot on the bottom of the outer shell; S2: The medicine in the medicine pot is atomized by the atomizing element, and the atomized medicine is blown to the pot mouth by the negative pressure element; S3: driving the component to inhale the gas in the gas cylinder and the atomized medicine into the outer shell through power control; S4: The power supply discharges again, pushing the component to push the medicine and gas out of the outer shell, so that the atomized medicine is quickly sprayed to form an air flow beam, which enters the human body through the skin or mucous membrane.

9. The method for needle-free injection of tumor drugs according to claim 8, characterized in that: In S3 and S4, the pushing component performs two actions, namely, sucking the gas inside the gas tank and pushing out the medicine through the electromagnetic field formed by the coil group. During the suction, only the coil group close to the medicine ejection end in the pushing component generates an electromagnetic field. During the ejection, the coil groups at both ends act simultaneously, and the electromagnetic field generated by the coil group far away from the medicine ejection end is greater than the electromagnetic field generated by the coil group at the other end.

10. The method for needle-free injection of tumor drugs according to claim 8, characterized in that: In the above-mentioned S4, the ejection speed of the medicine is 150 m / s-300 m / s.

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