Preparation of breast conditioning ointment

Abstract

The invention discloses an ointment composition for conditioning mammary glands and a preparation method of the ointment composition. The composition is prepared from the following raw materials in parts by mass: 5 to 50 parts of spica prunellae, 5 to 50 parts of herba hedyotidis diffusae, 50 to 200 parts of rhizoma coptidis, 50 to 200 parts of radix scutellariae, 50 to 200 parts of cortex phellodendri, 50 to 200 parts of radix astragali seu hedysari, 10 to 200 parts of radix notoginseng, 10 to 200 parts of radix angelicae sinensis, 50 to 200 parts of silkworm larva, 50 to 200 parts of semen pharbitidis, 10 to 50 parts of white lime, 10 to 50 parts of talcum powder and the like. The solid raw materials are respectively ground and sieved into powder of more than 100 meshes, the powder is mixed according to the proportion of the formula, rosa roxburghii tratt, tribulus terrestris or agilawood seed oil is added into sesame oil, and the mixture is blended with glycerin or sesame oil to prepare the ointment. The traditional Chinese medicine composition is used for conditioning mammary glands, has the effects of softening hardness to dissipate stagnation, removing blood stasis and activating collaterals, is mild in medicine property, good in permeability and free of toxic and side effects, reaches 5 mm or above of mammary glands and interstices, and is used for daily mammary gland conditioning and maintenance and mammary gland disease prevention; the composition is suitable for mammary gland syndromes such as breast pain, breast lumps, milk discharge, hyperplasia of mammary glands, mammary gland fibroma, mammary cyst, mammary nodule, plasma cell mastitis and the like.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine health care and cosmetics, in particular to an ointment for breast conditioning. Background Art

[0002] The mammary gland is located between the superficial and deep layers of the subcutaneous superficial fascia. The mammary gland is a vital organ in the human body, especially in women, responsible for development, growth, and overall health. Hormones produced by the mammary gland through the endocrine system (such as thyroxine and thyroid-stimulating hormone) effectively regulate body temperature, blood sugar, hormone levels, somatic cell proliferation, body tissue and structure, reproductive health, and other physiological and metabolic indicators.

[0003] Common female breast diseases include: breast hyperplasia, mastitis, acute mastitis, breast cancer, etc.

[0004] Fibrocystic breast disease is the most common breast disease in women. It manifests as hyperplasia of the mammary epithelium and fibrous tissue, structural degeneration of the mammary ducts and lobules, and progressive growth of connective tissue. In Traditional Chinese Medicine, fibrocystic breast disease is classified as a "breast disease." Its etiology and pathogenesis are primarily attributed to liver depression, spleen deficiency, kidney deficiency, Chong and Ren meridian imbalance, and the resulting qi stagnation, phlegm congestion, and blood stasis. Fibrocystic breast disease ranks first among breast diseases, accounting for approximately 60%-70% of cases, and has a certain tendency to become cancerous.

[0005] The function of promoting blood circulation and dispersing stagnation in traditional Chinese medicine has a significant effect on breast conditioning, and can also regulate body temperature and blood sugar levels. Some of the commonly used important traditional Chinese medicines and their main functions are: Chuanxiong, which has the effect of promoting blood circulation and promoting qi; peach kernel (fried), which has the effect of promoting blood circulation and dispersing swelling; white mustard seed, which can relieve liver depression; pangolin beads, which have the effect of promoting blood circulation and can regulate anticoagulant effects; dog meat (yam) and trillium, which have the effects of removing wind, promoting blood circulation, reducing swelling and clearing pus; usually these traditional Chinese medicines mainly promote the recovery of breast function by regulating hormone levels.

[0006] In 2015, Ma Nanxing et al. (Application No. CN201510076013.1) invented a breast conditioning and maintenance composition with breast enhancement properties. This composition includes peony flower, oat, licorice, scutellaria baicalensis, matricaria, olive leaf, myrrh, frankincense, camellia seed oil, linoleic acid, linolenic acid, butylene glycol, glycerin, squalane, caprylic / capric / stearic triglyceride, isopropyl myristate, glyceryl polymethacrylate, polydimethylsiloxane, glyceryl stearate, xanthan gum, sodium hyaluronate, methylparaben, propylparaben, etc. Qu Fujiang et al. (Application No. CN201510345662.7) invented a traditional Chinese medicine composition for treating breast hyperplasia, mainly including Cyperus rotundus, Citrus aurantium, Citrus reticulata, Prunella vulgaris, Dandelion, Trichosanthes kirilowii, Tribulus terrestris, Laminaria japonica, Sargassum macrophylla, and tangerine peel. In 2017, Liu Xingxian (application number CN201710958520.7) invented a conditioning solution for improving breast diseases, the main ingredients of which are red root, dandelion, kudzu root, golden cap, tangerine peel, sophora flavescens, and rhizoma schizonepetae. In 2018, Wei Jieyun et al. (application number CN201810699036.1) invented a traditional Chinese medicine ointment for treating breast hyperplasia, the main ingredients of which are Chuanxiong, peach kernel, pangolin beads, stir-fried white mustard seeds, lindera scutellariae, honeysuckle thorn, trillium, zedoaria, angelica, kudzu root, borneol, frankincense, scutellaria baicalensis, zedoaria officinalis, mirabilite, corydalis yanhusuo, strychnine seeds, polyanthus polyphylla, millettia repens, cynanchum chinense, rhodiola rosea, psoralea corylifolia, and dipsacus root. In 2019, Dai Yan and Dai Wenyi (application number CN201910296611.8) invented a traditional Chinese medicine composition for treating breast diseases, including motherwort, rose, half-branch lotus, pine pollen, kelp, edible sodium sulfate, and Panax notoginseng. In 2023, Guo Li (application number CN202311318743.9) invented a pure natural herbal breast dredging essence containing cyperus rotundus, cinnamon bark, jasmine, tangerine peel, peppermint, angelica, ginger root, Rosa centifolia, sweet almond, and caprylic / capric triglyceride or sunflower seed oil. In 2024, Ye Yuanyun (application number CN202411652526.8) invented a compound Chinese medicine patch for regulating breast hyperplasia. The functional ingredients mainly include bupleurum, white peony root, cyperus rotundus, costus root, green peel, fructus aurantii, angelica, safflower, peach kernel, ligusticum chuanxiong, licorice, dopamine hydrochloride, ethyl oleate, menthol, camphor essential oil, etc.

[0007] At present, breast conditioning technology mainly focuses on the following aspects: (1) the mechanism of promoting blood circulation, dispersing stagnation and reducing swelling and relieving pain, which supports breast conditioning through the blood circulation function of traditional Chinese medicine system; (2) hormone regulation, which combines the traditional Chinese medicine system of traditional Chinese medicine and modern scientific research to improve the balance of the endocrine system; (3) massage therapy, as a non-drug external treatment method, to assist in the prevention and relief of breast diseases. These technologies make breast conditioning more scientific and personalized, and improve breast function and health through a variety of methods. Summary of the Invention

[0008] The present invention aims to provide a composition for breast conditioning ointment and a preparation method thereof.

[0009] The technical solution adopted by the present invention is:

[0010] A traditional Chinese medicine composition for conditioning the mammary gland, the composition comprising the following raw materials in parts by mass: 5-50 parts of Prunella Vulgaris, 5-50 parts of Hedyotis diffusa, 50-200 parts of Gentiana macrophylla, 50-200 parts of Coptis chinensis, 50-200 parts of Scutellaria baicalensis, 50-200 parts of Phellodendron amurense, 50-200 parts of Astragalus membranaceus, 10-200 parts of Panax notoginseng, 10-200 parts of Angelica sinensis, 50-200 parts of Bombyx batryticatus, 50-200 parts of White morning glory, 10-50 parts of white lime, 10-50 parts of talc, 10-200 parts of glycerin, and 10-200 parts of sesame oil. In the specific implementation of the preparation, several appropriate raw materials are selected and combined.

[0011] The basic functions of the components of the Chinese medicine composition of the present invention are as follows:

[0012] Prunella Vulgaris: bitter and pungent in taste, cold in nature, enters the liver and gallbladder meridians, has the effect of clearing liver fire and relieving depression;

[0013] Hedyotis diffusa: bitter, light, and cold in nature, its main functions are clearing away heat and detoxifying, relieving pain and dispersing stagnation, and promoting diuresis and removing dampness. It is especially good at treating various types of inflammation.

[0014] Gentiana macrophylla: pungent, bitter and flat in nature, it enters the stomach, liver and gallbladder meridians and has the effects of dispelling rheumatism, relieving pain, relieving deficiency fever and clearing damp heat.

[0015] Coptis chinensis: bitter and cold in nature, it enters the heart, spleen, stomach, liver, gallbladder, and large intestine meridians, and has the effects of clearing heat and dampness, purging fire and detoxifying;

[0016] Scutellaria baicalensis: bitter and cold in nature, it enters the lung, gallbladder, spleen, large intestine and small intestine meridians, and has the effects of clearing heat and dampness, purging fire and detoxifying, cooling blood and stopping bleeding;

[0017] Huang Bai: bitter, cold, and sinking in nature, it is good at clearing away dampness and heat in the lower jiao, clearing away heat and dampness, and purging fire and detoxifying.

[0018] Astragalus: sweet in taste and warm in nature, it mainly enters the lung and spleen meridians, and has the effects of strengthening the spleen and lungs, promoting diuresis and reducing swelling, strengthening the exterior and stopping sweating, and supporting sores and promoting tissue regeneration.

[0019] Panax notoginseng: sweet and cool in nature, it has the effects of removing blood stasis, stopping bleeding, promoting blood circulation and relieving pain;

[0020] Angelica sinensis: warm in nature, sweet and spicy in taste, enters the liver meridian, heart meridian, and spleen meridian. Its effects are to nourish blood, regulate menstruation and relieve pain, and moisten the intestines and promote bowel movements.

[0021] Bombyx batryticatus: pungent and salty in taste, neutral in nature, has the effects of dispelling wind and relieving spasms, resolving phlegm and dispersing nodules;

[0022] White morning glory: bitter in taste, cold in nature, has the effects of clearing away heat and detoxifying, dispelling wind and dampness, promoting blood circulation and relieving pain;

[0023] White lime: Mainly used as an auxiliary additive for the above-mentioned pharmaceutical compositions, and can also be used as an intermediate in the synthesis of certain drugs, because the calcium contained in it may participate in the formation of some biologically active molecules;

[0024] Talc: As an auxiliary additive of the above-mentioned pharmaceutical composition, it has sweet, light and cold properties, and has the effects of antibacterial, moisture-absorbing and sore-healing, heat-clearing, diuretic, and intestinal wall protection;

[0025] Glycerin: As a blending agent for the above-mentioned pharmaceutical composition ointment, it has the functions of moisturizing, hydrating, sun-proofing and nourishing the skin;

[0026] Sesame oil: As a blending and modulating agent for the above-mentioned pharmaceutical composition ointment, it is sweet and cool in nature, and has the effects of moistening the intestines, promoting bowel movements, detoxifying and promoting tissue regeneration.

[0027] The preparation method of the Chinese medicine composition of the present invention is as follows:

[0028] 1. Prepare the ingredients. Prepare the basic Chinese medicinal raw materials for making the ointment, mainly including Prunella Vulgaris, Hedyotis Diffusa, Gentiana Macrophylla, Coptis chinensis, Scutellaria baicalensis, Phellodendron amurense, Astragalus membranaceus, Panax notoginseng, Angelica sinensis, Bombyx batryticatus, and Psoralea corylifolia. Also prepare auxiliary materials for blending, such as white lime and talcum powder. Liquid glycerin and sesame oil are also needed for the preparation of the ointment. The sesame oil needs to be freshly squeezed from sesame seeds. Sesame seeds also need to be mixed with a small amount of Rosa roxburghii seeds, Tribulus terrestris seeds, and Aquilaria sinensis seeds. Prepare the appropriate amount.

[0029] 2. The raw materials are powdered separately. All the above-mentioned plant or solid raw materials are separated, and each raw material is ground into powder separately. According to the characteristics of the raw materials themselves, after proper drying and removal of moisture, the large pieces of raw materials are first sheared or crushed appropriately, or they are then crushed with a grinder. The coarse powder after crushing is then finely ground with a grinder or fine grinder. The obtained powder is sieved with a sieve of 200 mesh or more, and the sieved fraction is retained. The coarser particle powder that is not sieved is finely ground again, and the sieved fractions are combined and mixed evenly to make a separate raw material powder.

[0030] 3. Powders are mixed according to the formula ratio. The various raw material powders are added one by one in a larger container according to the following mass ratio: 5-50 parts of Prunella Vulgaris, 5-50 parts of Hedyotis diffusa, 50-200 parts of Gentiana macrophylla, 50-200 parts of Coptis chinensis, 50-200 parts of Scutellaria baicalensis, 50-200 parts of Phellodendron amurense, 50-200 parts of Astragalus membranaceus, 10-200 parts of Panax notoginseng, 10-200 parts of Angelica sinensis, 50-200 parts of Bombyx batryticatus, 50-200 parts of White morning glory, 10-50 parts of lime, and 10-50 parts of talc. After all the powders are added, stir them repeatedly to mix them evenly.

[0031] 4. Blending oil to form an ointment. The oil used for blending or preparing can be glycerin or sesame oil. Glycerin or sesame oil alone can be used, or glycerin and sesame oil can be mixed in a certain proportion. When sesame oil is used, a small amount of roxburgh seeds, tribulus terrestris seeds, or agarwood seeds needs to be added to the sesame seeds before squeezing the oil. The added ratio is sesame seeds: roxburgh / tribulus terrestris / agarwood = 5000 grams: 1 to 500 grams. After adding, the mixture is mixed together to squeeze out sesame oil. The oil is slowly added to the uniformly mixed raw material powder while stirring, and the oil is blended to form an ointment with suitable viscosity.

[0032] The breast conditioning ointment produced by the present invention is used for breast conditioning and has the effects of softening and dispersing lumps, removing blood stasis and activating collaterals. It has mild medicinal properties, is soothing and smooth, is easily dispersed, has good skin permeability, can reach more than 5 mm of breast pores, has no toxic side effects, can be used for daily breast conditioning and maintenance, prevents the occurrence of breast diseases, and is suitable for breast syndromes such as premenstrual breast pain, hard lumps felt by touch, discharge, breast hyperplasia, breast fibroma, breast cyst, breast nodules and plasma cell mastitis. DETAILED DESCRIPTION

[0033] 1. A composition for a breast conditioning ointment and its preparation method. The composition comprises the following raw materials in parts by weight: 5 parts of Prunella Vulgaris, 5 parts of Hedyotis diffusa, 80 parts of Gentiana macrophylla, 50 parts of Coptis chinensis, 60 parts of Scutellaria baicalensis, 50 parts of Phellodendron amurense, 60 parts of Astragalus membranaceus, 10 parts of Panax notoginseng, 10 parts of Angelica sinensis, 60 parts of Bombyx batryticatus, 70 parts of Pharbitis ulmoides, 20 parts of lime, 20 parts of talc, 10 parts of glycerin, and 50 parts of sesame oil. The solid raw materials are ground and sieved into powders with a mesh size of 200 or larger, the powders are mixed according to the formula ratio, and then blended with glycerin or sesame oil to form an ointment.

[0034] 2. A composition for a breast conditioning ointment and its preparation method. The composition comprises the following raw materials in parts by weight: 30 parts of Prunella Vulgaris, 20 parts of Hedyotis diffusa, 70 parts of Gentiana macrophylla, 50 parts of Coptis chinensis, 50 parts of Scutellaria baicalensis, 50 parts of Phellodendron amurense, 50 parts of Astragalus membranaceus, 70 parts of Bombyx batryticatus, 70 parts of Pharbitis nigra, 20 parts of lime, 20 parts of talc, 20 parts of glycerin, and 50 parts of sesame oil. The solid raw materials are ground and sieved into powders with a mesh size of 200 or larger, and the powders are mixed according to the formula ratio and then blended with glycerin or sesame oil to form an ointment.

[0035] 3. A composition for a breast conditioning ointment and its preparation method. The composition comprises the following raw materials by weight: 80 parts of Gentiana macrophylla, 60 parts of Coptis chinensis, 60 parts of Scutellaria baicalensis, 60 parts of Phellodendron amurense, 60 parts of Astragalus membranaceus, 70 parts of Bombyx batryticatus, 70 parts of Pharbitis nigra, 20 parts of lime, 20 parts of talc, and 60 parts of sesame oil. The solid raw materials are ground and sieved into powders with a mesh size of 200 or larger. The powders are mixed according to the formula ratio and then blended with glycerin or sesame oil to form an ointment.

Claims

1. An ointment composition for breast conditioning and a preparation method thereof.

2. The composition according to claim 1, characterized in that The composition comprises the following raw materials in parts by mass: 5-50 parts of Prunella Vulgaris, 5-50 parts of Hedyotis diffusa, 50-200 parts of Gentiana macrophylla, 50-200 parts of Coptis chinensis, 50-200 parts of Scutellaria baicalensis, 50-200 parts of Phellodendron amurense, 50-200 parts of Astragalus membranaceus, 10-200 parts of Panax notoginseng, 10-200 parts of Angelica sinensis, 50-200 parts of Bombyx batryticatus, and 50-200 parts of White morning glory, among which 11 kinds of Chinese medicinal raw materials are included; 10-50 parts of white lime and 10-50 parts of talc are used as auxiliary additives for preparing the ointment; and 10-200 parts of glycerin and 10-200 parts of sesame oil are selected, one or two of which are used as ointment modifiers to promote skin penetration.

3. The preparation method according to claim 1, characterized in that The preparation method is as follows: each Chinese medicinal raw material is ground or milled separately, and then sieved into powder with a mesh size of more than 100, the powders are mixed according to a formula ratio, and then blended with glycerin or sesame oil to form an ointment.

4. The ointment for breast conditioning according to claim 1, characterized in that This ointment is used for breast conditioning and has the effects of softening and dispersing nodules, removing blood stasis and activating blood circulation. It has mild medicinal properties, good skin permeability, can reach more than 5 mm of breast pores, and has no toxic side effects.

5. The ointment for breast conditioning according to claim 1, characterized in that This ointment can be used for daily breast conditioning and maintenance, and to prevent breast diseases. It is suitable for breast syndromes such as premenstrual breast pain, breast lumps, milk discharge, breast hyperplasia, breast fibroids, breast cysts, breast nodules and plasma cell mastitis.

6. The 11 raw materials according to claim 2, characterized in that: When making the ointment from the 11 raw materials, you can choose only one of them, or choose several of them, or choose all 11 of them.

7. The ointment preparation according to claim 2, characterized in that The ointment can be prepared by selecting one or both of glycerol and sesame oil to prepare the ointment, or can be directly prepared into a powder preparation without adding glycerol or sesame oil.

8. The sesame oil according to claim 3, wherein Sesame oil is squeezed from sesame seeds. During squeezing, a small amount of one or more of roxburghii seeds, tribulus terrestris seeds or agarwood seeds is added and mixed into the sesame seeds, with the adding ratio being 5000 grams:1 to 500 grams.