Double-layer plate type magnetic hyperthermia treatment device for pets

Abstract

The invention discloses a double-layer plate type magnetic hyperthermia treatment device for pets, and the device comprises a main unit which comprises a bearing platform and a support disposed on the bearing platform; the coil assembly comprises a first treatment plate and a second treatment plate, the first treatment plate is arranged on the support, the second treatment plate is arranged on the bearing table, and orthographic projections of the first treatment plate and the second treatment plate on the vertical plane in the first direction are at least partially overlapped to form an induction area; the sliding plate is arranged on the side, facing the first treatment plate, of the second treatment plate, extends in the first direction, protrudes out of the two ends of the second treatment plate and is used for bearing a treatment object with the focus portion implanted with the magnetic medium so as to generate an alternating magnetic field in the induction area. By arranging the bearing table, the coil assembly and the sliding plate, when the coil assembly is electrified, the focus part of a treatment object generates an alternating magnetic field in the cavity, and magnetic hyperthermia is carried out on the treatment object; the device is simple in structure, convenient to install and more convenient to operate.

Description

Technical Field

[0001] The present invention belongs to the technical field of electromagnetic induction, and in particular relates to a double-layer plate-type magnetic hyperthermia treatment device for pets. Background Art

[0002] In the field of clinical tumor treatment for pets, traditional methods such as surgical resection, radiotherapy, and chemotherapy all have significant limitations. Magnetic Hyperthermia Therapy (MHT) has gradually attracted attention due to its minimally invasive and targeted nature. It offers advantages such as unlimited depth, precise targeting, and repeatable treatment. However, it has the following inherent drawbacks: the lack of an operating console or poorly designed operating console makes the therapeutic device unsuitable for clinical use in pets; the mechanical structure is complex, energy consumption is excessive, and the equipment requires a large footprint; and the lack of modular mechanical design requires integration with improved distributed magnetic field generation technology.

[0003] To sum up, the pet magnetic hyperthermia therapy device needs to be further improved, and proposing a magnetic induction tumor treatment technology solution with a more reasonable layout, better application effect, and more convenient control is a technical problem that technical personnel in this field urgently need to solve. Summary of the Invention

[0004] In order to solve the above problems, the primary purpose of the present invention is to provide a double-layer plate-type pet magnetic hyperthermia treatment device, which is used to solve the technical problems that the current device has a complex mechanical structure, is not suitable for pet clinical applications, and lacks a reasonable combination of mechanical design and magnetic field distribution generation technology.

[0005] To achieve the above object, the technical solution of the present invention is as follows:

[0006] The present invention provides a double-layer plate-type pet magnetic hyperthermia treatment device, comprising:

[0007] The main unit includes a carrying platform and a bracket, wherein the bracket is arranged on the carrying platform;

[0008] The coil assembly includes a first treatment plate and a second treatment plate, wherein the first treatment plate is disposed on the bracket and the second treatment plate is disposed on the supporting platform, and the orthographic projections of the first treatment plate and the second treatment plate on a vertical plane in a first direction at least partially overlap to form an induction area;

[0009] A sliding plate is arranged on the side of the second treatment plate facing the first treatment plate. The sliding plate extends along the first direction and protrudes from the two end portions of the second treatment plate, and is used to support the treatment object with a magnetic medium implanted in the lesion site to generate an alternating magnetic field in the induction area.

[0010] The double-layer plate type pet magnetic hyperthermia treatment device of the present invention is configured by arranging a first treatment plate on a bracket and a second treatment plate on a supporting platform, wherein the orthographic projections of the first treatment plate and the second treatment plate on a vertical plane in a first direction at least partially overlap to form an induction area, so that an alternating magnetic field can be generated in the induction area for a treatment object with a magnetic medium implanted in the lesion site; a sliding plate is arranged on a side of the second treatment plate facing the first treatment plate and is used to support the treatment object with a magnetic medium implanted in the lesion site, the sliding plate extends along the first direction and protrudes from both end portions of the second treatment plate; when the treatment object with a magnetic medium implanted in the lesion site passes through the alternating magnetic field, current is passed into the first treatment plate or the second treatment plate to achieve the purpose of generating an alternating magnetic field at the lesion site of the treatment object for magnetic hyperthermia treatment.

[0011] Furthermore, a plurality of first magnetic conductive blocks are provided on the side of the first treatment plate facing the second treatment plate; a plurality of second magnetic conductive blocks are provided on the side of the second treatment plate facing the first treatment plate; the first magnetic conductive blocks and the second magnetic conductive blocks are aligned along the third direction; any one of the first magnetic conductive blocks and the second magnetic conductive blocks are spaced apart along the first direction; any one of the first magnetic conductive blocks and the second magnetic conductive blocks are spaced apart along the second direction. By aligning the first magnetic conductive blocks and the second magnetic conductive blocks in the third direction, the induction area can be maximized. By setting the relative position between the first magnetic conductive blocks and the second magnetic conductive blocks, the structural design diversity of the first coil assembly and the second coil assembly is increased, and more embodiments can be applicable to different needs of treatment objects on the market, such as more suitable for treatment objects of different species, different body shapes or different degrees of magnetic hyperthermia.

[0012] Furthermore, along the first direction, a first spacing is formed between adjacent first magnetic conductive blocks, and a third spacing is formed between adjacent second magnetic conductive blocks; along the second direction, a second spacing is formed between adjacent first magnetic conductive blocks, and a fourth spacing is formed between adjacent second magnetic conductive blocks; the first spacing, the second spacing, the third spacing, and the fourth spacing are all constant values; the first spacing is equal to the second spacing; and the third spacing is equal to the fourth spacing. By setting the values of the first spacing, the second spacing, the third spacing, and the fourth spacing, the structural design of the first coil assembly and the second coil assembly is simplified, and the first treatment plate and the second treatment plate can generate a more stable alternating magnetic field range when current is passed through them, thereby achieving better magnetic hyperthermia treatment for the treatment object.

[0013] Furthermore, the invention further includes a cooling assembly disposed on opposite sides of the first and second treatment plates; the cooling assembly contacts the surface of the first treatment plate facing away from the second treatment plate; and the cooling assembly contacts the surface of the second treatment plate facing away from the first treatment plate. By disposing the cooling assembly in contact with the first or second treatment plate, the first or second treatment plate is fully cooled by the cooling assembly, thereby reducing heat loss in the first or second coil assembly.

[0014] Furthermore, the cooling assembly includes: a housing frame including a bottom plate, side plates protruding from an edge of the bottom plate, and a connecting plate, wherein the side plates and the bottom plate enclose a housing cavity, the connecting plate being disposed on a side of the side plate away from the housing cavity and connected to the first treatment plate or the second treatment plate; a mold disposed in the housing cavity, the mold having a reflux groove disposed on a side of the mold away from the bottom plate; and a cooling element adapted to fit within the reflux groove. By arranging the cooling element, the mold, the housing frame, and the connecting plate, the bottom plate, the mold, the cooling element, and the first treatment plate are sequentially stacked, or the bottom plate, the mold, the cooling element, and the second treatment plate are sequentially stacked, and the first treatment plate, the cooling element, and the mold are sequentially adapted within the housing cavity, or the second treatment plate, the cooling element, and the mold are sequentially adapted within the housing cavity, and the connecting plate is used to connect the housing frame to the first treatment plate or the second treatment plate, so that the cooling element cools the first treatment plate or the second treatment plate with a maximum contact area, thereby maximizing the cooling effect.

[0015] The cooling assembly further includes: a first connector, disposed on the side panel, one end of which extends to the outside of the housing frame and the other end of which connects the housing cavity and the cooling element; and a second connector, one end of which connects to the mold and the other end of which passes through the side panel and extends to the outside of the housing frame. The first connector connects the cooling element to the outside of the housing frame, facilitating connection or disconnection of the first connector to an external cooling source, and the second connector allows the mold to be mounted on the housing frame.

[0016] Furthermore, the host also includes a control component, which is electrically connected to the sliding plate and is used to drive the sliding plate to move in a direction, displacement, or speed relative to the supporting platform. When the double-layer plate-type pet magnetic hyperthermia treatment device needs to be operated, the control component first controls the sliding plate to move along a first direction toward the end away from the induction area. The treatment object with the lesion site already implanted with a magnetic medium is placed on the sliding plate. The control component first controls the sliding plate to move toward the end close to the induction area. The treatment object with the lesion site already implanted with a magnetic medium is moved into the induction area. Therefore, when the first coil assembly or the second coil assembly provides an alternating current, an alternating magnetic field is generated in the induction area for the treatment object to perform magnetic hyperthermia treatment.

[0017] Furthermore, it further comprises a lifting assembly, wherein the lifting assembly is arranged between the side of the cooling assembly facing away from the first treatment plate and the bracket, or the lifting assembly is arranged between the side of the cooling assembly facing away from the second treatment plate and the supporting platform;

[0018] The control assembly is connected to the lifting assembly, and is used to control the lifting assembly to drive the cooling mechanism and the first treatment plate to move, and to control the lifting assembly to drive the cooling assembly and the second treatment plate to move. When the lifting assembly is controlled by the control assembly to move the first treatment plate toward the side closer to the second treatment plate, or when the lifting assembly is controlled to move the second treatment plate toward the side closer to the first treatment plate, the height of the induction area is reduced, the generated magnetic field is strengthened, and the magnetic hyperthermia effect is enhanced. When the lifting assembly is controlled by the control assembly to move the first treatment plate toward the side farther from the second treatment plate, or when the lifting assembly is controlled to move the second treatment plate toward the side farther from the first treatment plate, the height of the induction area is increased, the generated magnetic field is weakened, and the magnetic hyperthermia effect is reduced.

[0019] Furthermore, the control assembly is connected to the cooling assembly and is used to control the cooling assembly to provide or stop providing a cooling source to the first or second treatment plate. By placing the cooling assembly in contact with the first or second treatment plate, the cooling assembly can fully cool the first or second treatment plate, thereby reducing heat loss from the first or second treatment plate. Furthermore, the control assembly is connected to the cooling assembly and is used to control the cooling assembly to provide or stop providing a cooling source to the first or second treatment plate.

[0020] Furthermore, the host further includes:

[0021] A power supply component is arranged on the supporting platform, the first treatment plate and / or the second treatment plate are connected to the power supply component and are used to provide alternating current to the first treatment plate and / or the second treatment plate; the control component is electrically connected to the power supply component and is used to control the intensity or frequency of the alternating current.

[0022] Furthermore, the sliding plate includes a first plate body and a second plate body that are arranged in contact with each other, the second plate body is arranged on the side of the first plate body close to the supporting platform, the two end portions of the first plate body are respectively protruded along the first direction at the two end portions of the second plate body, and the second plate body is connected to the side of the second treatment plate close to the first treatment plate.

[0023] The beneficial effects of the present invention are as follows: compared with the prior art, the present application sets a first treatment plate on the bracket and a second treatment plate on the supporting platform, and the orthographic projections of the first treatment plate and the second treatment plate on the vertical plane in the first direction at least partially overlap to form an induction area, so that the treatment object with the magnetic medium implanted in the lesion site can generate an alternating magnetic field in the induction area; by setting a sliding plate on the side of the second treatment plate facing the first treatment plate and used to support the treatment object with the magnetic medium implanted in the lesion site, the sliding plate extends along the first direction and protrudes from the two end portions of the second treatment plate; when the treatment object with the magnetic medium implanted in the lesion site passes through the alternating magnetic field, current is passed into the first treatment plate or the second treatment plate to generate an alternating magnetic field at the lesion site of the treatment object, thereby performing magnetic hyperthermia therapy on the treatment object; at the same time, the structure of the present application is simple and easy to install, making operation more convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a three-dimensional schematic diagram of a double-layer plate pet magnetic hyperthermia treatment device.

[0025] Figure 2 This is an exploded view of a double-layer plate pet magnetic hyperthermia treatment device.

[0026] Figure 3 yes Figure 3 Partial exploded view of the first treatment plate and cooling assembly.

[0027] Figure 4 yes Figure 3 Partial exploded view of the second treatment plate and cooling assembly.

[0028] In the figure: 10, main unit; 11, supporting platform; 12, bracket; 13, first coil assembly; 131, first treatment plate; 132, first magnetic conductive block; 14, second coil assembly; 141, second treatment plate; 142, second magnetic conductive block; 15, cooling assembly; 151, accommodating frame; 152, side panel; 153, bottom panel; 154, accommodating cavity; 155, connecting plate; 156, mold; 157, reflux groove; 158, cooling part; 159, first conductive part; 150, second conductive part; 16, lifting assembly; 17, control assembly; 18, power supply assembly; 20, sliding plate; 21, first plate body; 22, second plate body. DETAILED DESCRIPTION

[0029] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0030] To achieve the above object, the technical solution of the present invention is as follows:

[0031] See also Figure 1-Figure 4 As shown, this embodiment provides a double-layer plate-type pet magnetic hyperthermia treatment device, comprising: a main unit 10, including a carrier 11, a bracket 12, the bracket 12 being disposed on the carrier 11; a first coil assembly 13, disposed on the bracket 12; a second coil assembly 14, disposed on the carrier 11; the first coil assembly 13 including a first treatment plate 131; the second coil assembly 14 including a second treatment plate 141; the orthographic projections of the first treatment plate 131 and the second treatment plate 141 on a vertical plane in a first direction at least partially overlap to form an induction area, which is used to generate an alternating magnetic field in the induction area for a treatment object in which a magnetic medium has been implanted at a lesion site;

[0032] The sliding plate 20 is arranged on the side of the second treatment plate 141 facing the first treatment plate 131 and is used to support the treatment object in which the magnetic medium has been implanted at the lesion site. The sliding plate 20 extends along the first direction and protrudes from the two end portions of the second treatment plate 141; wherein the first direction is the longitudinal direction of the sliding plate 20.

[0033] The double-layer plate type pet magnetic hyperthermia treatment device of the present invention is configured by arranging a first treatment plate 131 on a bracket 12 and a second treatment plate 141 on a supporting platform 11. The orthographic projections of the first treatment plate 131 and the second treatment plate 141 on a vertical plane in a first direction at least partially overlap to form an induction area, so that the treatment object with a magnetic medium implanted in the lesion site can generate an alternating magnetic field in the induction area; by arranging a sliding plate 20 on the side of the second treatment plate 141 facing the first treatment plate 131 and used to support the treatment object with a magnetic medium implanted in the lesion site, the sliding plate 20 extends along the first direction and protrudes from the two end portions of the second treatment plate 141; when the treatment object with a magnetic medium implanted in the lesion site passes through the induction area, current is passed into the first treatment plate 131 or the second treatment plate 141 to generate an alternating magnetic field at the lesion site of the treatment object for the purpose of magnetic hyperthermia therapy.

[0034] Furthermore, a plurality of first magnetic conductive blocks 132 are provided on a side of the first treatment plate 131 facing the second treatment plate 141 , and a plurality of second magnetic conductive blocks 142 are provided on a side of the second treatment plate 141 facing the first treatment plate 131 .

[0035] Furthermore, the first magnetic conductive block 132 and the second magnetic conductive block 142 are aligned along a third direction, where the second treatment plate 141 points toward the first treatment plate 131. By aligning the first magnetic conductive block 132 and the second magnetic conductive block 142 in the third direction, the sensing area can be maximized.

[0036] Furthermore, either the first magnetic conductive blocks 132 or the second magnetic conductive blocks 142 are spaced apart along the first direction, and either the first magnetic conductive blocks 132 or the second magnetic conductive blocks 142 are spaced apart along the second direction; wherein any two of the second direction, the third direction, and the first direction intersect perpendicularly. The relative positioning of the first magnetic conductive blocks 132 and the second magnetic conductive blocks 142 increases the structural design diversity of the first coil assembly 13 and the second coil assembly 14, allowing for a wider range of embodiments to meet the diverse needs of treatment subjects in the market, such as those of different species, body types, or with varying degrees of magnetic hyperthermia.

[0037] Furthermore, a first spacing is formed between adjacent first magnetic conductive blocks 132 along the first direction; a second spacing is formed between adjacent first magnetic conductive blocks 132 along the second direction; a third spacing is formed between adjacent second magnetic conductive blocks 142 along the first direction; and a fourth spacing is formed between adjacent second magnetic conductive blocks 142 along the second direction. By setting the first, second, third, and fourth spacings, the first and second coil assemblies 13 and 14 can generate a more stable alternating magnetic field range when current is passed through them, thereby achieving better magnetic hyperthermia treatment for the treated subject.

[0038] Furthermore, the first spacing, the second spacing, the third spacing and the fourth spacing are all constant values.

[0039] Furthermore, the first spacing is equal to the second spacing, and the third spacing is equal to the fourth spacing. By setting the values of the first spacing, the second spacing, the third spacing, and the fourth spacing, the structural design of the first coil assembly 13 and the second coil assembly 14 is simplified.

[0040] Furthermore, the double-layer plate-type pet magnetic hyperthermia treatment device of the present invention further includes cooling assemblies 15, disposed on opposite sides of the first treatment plate 131 and the second treatment plate 141. One group of cooling assemblies 15 contacts the surface of the first treatment plate 131 facing away from the second treatment plate 141, while another group of cooling assemblies 15 contacts the surface of the second treatment plate 141 facing away from the first treatment plate 131. By disposing the cooling assemblies 15 in contact with the first treatment plate 131 or the second treatment plate 141, the cooling assemblies 15 can fully cool the first treatment plate 131 or the second treatment plate 141, thereby reducing heat loss in the first coil assembly 13 or the second coil assembly 14.

[0041] Furthermore, the cooling assembly 15 includes: a accommodating frame 151, a mold 156 and a cooling member 158; the accommodating frame 151 includes a bottom plate 153, a side plate 152 protruding around the edge of the bottom plate 153 and a connecting plate 155, the side plate 152 and the bottom plate 153 enclose a accommodating cavity 154, the connecting plate 155 is arranged on the outside of the side plate 152 and is used to connect the first treatment plate 131 or the second treatment plate 141; the mold 156 is arranged in the accommodating cavity 154, and a reflux groove 157 is provided on the side of the mold 156 facing away from the bottom plate 153; the cooling member 158 is adapted to be in the reflux groove 157. By arranging the cooling member 158, the mold 156, the accommodating frame 151 and the connecting plate 155, the base plate 153, the mold 156, the cooling member 158 and the first treatment plate 131 are stacked in sequence, or the base plate 153, the mold 156, the cooling member 158 and the second treatment plate 141 are stacked in sequence, and the first treatment plate 131, the cooling member 158 and the mold 156 are sequentially adapted in the accommodating cavity 154, or the second treatment plate 141, the cooling member 158 and the mold 156 are sequentially adapted in the accommodating cavity 154, and the connecting plate 155 is used to connect the accommodating frame 151 to the first treatment plate 131, or the connecting plate 155 is used to connect the accommodating frame 151 to the second treatment plate 141, so that the cooling member 158 cools the first treatment plate 131 or the second treatment plate 141 with the maximum contact area, thereby maximizing the cooling effect.

[0042] Furthermore, the cooling assembly 15 also includes a first connecting member 159 connected to the side plate 152, one end of which extends outside the accommodating frame 151 and the other end of which communicates with the accommodating cavity 151 and the cooling member 158; and a second connecting member 150, one end of which is connected to the mold 156 and the other end of which passes through the side plate 152 and extends outside the accommodating frame 151. The first connecting member 159 connects the cooling member 158 to the outside of the accommodating frame 151, facilitating connection or disconnection of the first connecting member 159 with an external cooling source. The second connecting member 150 secures the mold 156 to the accommodating frame 151.

[0043] Furthermore, the double-layer plate type pet magnetic hyperthermia treatment device of the present invention also includes a control component 17, which is arranged on the supporting platform 11. The control component 17 is electrically connected to the sliding plate 20, and the control component 17 is used to drive the movement direction, displacement or speed of the sliding plate 20 relative to the supporting platform 11. When the double-layer plate type pet magnetic hyperthermia treatment device needs to work, the control component 17 first controls the sliding plate 20 to move along the first direction toward the end away from the induction area, and the treatment object with the magnetic medium implanted in the lesion area is placed on the sliding plate 20. The control component 17 first controls the sliding plate 20 to move toward the end close to the induction area, and the treatment object with the magnetic medium implanted in the lesion area moves into the induction area, so that when the first coil assembly 13 or the second coil assembly 14 provides an alternating current, the treatment object generates an alternating magnetic field in the induction area for magnetic hyperthermia treatment.

[0044] Furthermore, the double-layer plate type pet magnetic hyperthermia treatment device of the present invention also includes a lifting component 16, which is arranged between the side of the cooling component 15 away from the first treatment plate 131 and the bracket 12, or the lifting component 16 is arranged between the side of the cooling component 15 away from the second treatment plate 141 and the main unit 10.

[0045] Furthermore, the control assembly 17 is connected to the lifting assembly 16. The control assembly 17 is used to control the lifting assembly 16 to move the cooling mechanism 15 and the first treatment plate 131 toward or away from the support platform 11, and to control the lifting assembly 16 to move the cooling assembly 15 and the second treatment plate 141 toward or away from the support 12. When the control assembly 17 controls the lifting assembly 16 to move the first treatment plate 131 toward the side closer to the second treatment plate 141, or controls the lifting assembly 16 to move the second treatment plate 141 toward the side closer to the first treatment plate 131, the height of the induction area is reduced, the generated magnetic field is strengthened, and the magnetic hyperthermia effect is enhanced. When the control assembly 17 controls the lifting assembly 16 to move the first treatment plate 131 away from the second treatment plate 141, or controls the lifting assembly 16 to move the second treatment plate 141 away from the first treatment plate 131, the height of the induction area is increased, the generated magnetic field is weakened, and the magnetic hyperthermia effect is reduced.

[0046] Furthermore, the control assembly 17 is connected to the cooling assembly 15 and is used to control the cooling assembly 15 to provide or stop providing a cooling source to the first treatment plate 131 or the second treatment plate 141. By placing the cooling assembly 15 in contact with the first treatment plate 131 or the second treatment plate 141, the cooling assembly 15 can fully cool the first treatment plate 131 or the second treatment plate 141, thereby reducing heat loss from the first treatment plate 131 or the second treatment plate 141. Furthermore, the control assembly 17 is connected to the cooling assembly 15 and is used to control the cooling assembly 15 to provide or stop providing a cooling source to the first treatment plate 131 or the second treatment plate 141.

[0047] Furthermore, the host 10 also includes: a power supply component 18, which is arranged on the supporting platform 11, the first treatment plate 131 and / or the second treatment plate 141 is connected to the power supply component 18, and is used to provide alternating current to the first treatment plate 131 and / or the second treatment plate 141; the control component 17 is connected to the power supply component 18, and is used to control the intensity or frequency of the alternating current.

[0048] Furthermore, the host 10 further includes: a transformer (not numbered), which is disposed on the carrier 11 and is connected to the power supply assembly 18 and is used to provide an alternating voltage to the power supply assembly 18;

[0049] The control component 17 is electrically connected to the transformer and is used to control the intensity or frequency of the alternating current.

[0050] Furthermore, the sliding plate 20 includes a first plate body 21 and a second plate body 22 that are arranged in contact with each other. The second plate body 22 is arranged on the side of the first plate body 21 close to the supporting platform 11. The two end portions of the first plate body 21 are respectively protruded along the first direction and arranged on the two end portions of the second plate body 22. The second plate body 22 is connected to the side of the second treatment plate 141 close to the first treatment plate 131.

[0051] The process of operating the double-layer plate-type pet magnetic hyperthermia treatment device of the present invention on a treatment object in which a magnetic medium has been implanted at the lesion site includes:

[0052] Take appropriate sanitation and disinfection measures before treatment, such as trimming the treatment area and disinfecting the injection area with iodine;

[0053] After determining the appropriate dose, draw the necessary volume into a sterile syringe using a 23-27 gauge needle;

[0054] To inject, insert the needle into a single injection site within the tumor mass. While applying even pressure to the syringe plunger, move the needle back and forth to inject the drug into different locations within the tumor. Ensure that the injection is confined to the tumor mass only and do not inject into the edges of the tumor or beyond its periphery.

[0055] After the entire dose of the veterinary drug has been injected, pause for 5 seconds to allow it to diffuse into the tissue before withdrawing the needle from the tumor;

[0056] After the injection, CT scans were used to locate the position of the magnetic fluid, and the pet was then placed in a magnetic field generating device;

[0057] Adjust the intensity and frequency of the magnetic field generator, wait until the temperature in the center of the hyperthermia treatment area reaches a stable 46°C, and then continue the treatment for another 15 minutes.

[0058] It should be noted that the magnetic medium implanted in the lesion site of the treatment object is equivalent to a magnetic fluid, the main component of which is PEG2000-coated ferroferric oxide nanoparticles with a concentration of 200 mg / mL, or a concentration of 112 mg / mL measured in Fe. The treatment object of the present invention is mainly used for cats and dogs with solid tumors, and is suitable for tumors with a volume of 1 cm 3 ~8cm 3 The magnetic fluid is stored in a vial for intratumoral injection, wherein the injection dose is per cm 3 Tumor volume was injected with 0.2ul magnetic fluid. The calculation formula of tumor size should meet the following requirements: tumor volume (cm 3 )=π / 6(length*width*height)). This tumor volume calculation formula is closer to the actual volume. The dose calculation formula satisfies: injection volume (mL)=tumor volume (cm 3 )*0.2.

[0059] The double-layer plate-type pet magnetic hyperthermia treatment device provided by the present invention is provided with a first coil assembly 13 on the bracket 12 and a second coil assembly on the supporting platform 11. The first coil assembly 13 includes a first treatment plate 131, and the second coil assembly 14 includes a second treatment plate 141. The orthographic projections of the first treatment plate 131 and the second treatment plate 141 on the vertical plane in the first direction at least partially overlap to form an induction area, so that the treatment object with the lesion site implanted with a magnetic medium can generate an alternating magnetic field within the induction area; by arranging the sliding plate 20 on the side of the second treatment plate 141 facing the first treatment plate 131 and being used to support the treatment object with the lesion site implanted with a magnetic medium, the sliding plate 20 extends along the first direction and protrudes from the two end portions of the second treatment plate 141; when the treatment object with the lesion site implanted with a magnetic medium passes through the alternating magnetic field, current is passed into the first treatment plate 131 or the second treatment plate 141 to generate an alternating magnetic field at the lesion site of the treatment object, thereby performing magnetic hyperthermia treatment on the treatment object; at the same time, the structure of the present application is simple and easy to install, making operation more convenient.

[0060] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A double-layer plate type pet magnetic hyperthermia treatment device, characterized in that: include: The main unit includes a carrying platform and a bracket, wherein the bracket is arranged on the carrying platform; The coil assembly includes a first treatment plate and a second treatment plate, wherein the first treatment plate is disposed on the bracket and the second treatment plate is disposed on the supporting platform, and the orthographic projections of the first treatment plate and the second treatment plate on a vertical plane in a first direction at least partially overlap to form an induction area; A sliding plate is arranged on the side of the second treatment plate facing the first treatment plate. The sliding plate extends along the first direction and protrudes from the two end portions of the second treatment plate, and is used to support the treatment object with a magnetic medium implanted in the lesion site to generate an alternating magnetic field in the induction area.

2. A double-layer plate type pet magnetic hyperthermia treatment device as claimed in claim 1, characterized in that: A plurality of first magnetic conductive blocks are provided on a side of the first treatment plate facing the second treatment plate; a plurality of second magnetic conductive blocks are provided on a side of the second treatment plate facing the first treatment plate; Along the third direction, the first magnetic conductive block and the second magnetic conductive block are aligned; Any one of the first magnetic conductive blocks and the second magnetic conductive blocks is arranged at intervals along the first direction; Any one of the first magnetic conductive blocks and the second magnetic conductive blocks is arranged at intervals along the second direction.

3. A double-layer plate type pet magnetic hyperthermia treatment device as claimed in claim 2, characterized in that: Along the first direction, a first spacing is formed between adjacent first magnetic conductive blocks, and a third spacing is formed between adjacent second magnetic conductive blocks; along the second direction, a second spacing is formed between adjacent first magnetic conductive blocks, and a fourth spacing is formed between adjacent second magnetic conductive blocks; The first spacing, the second spacing, the third spacing and the fourth spacing are all constant values; the first spacing is equal to the second spacing; and the third spacing is equal to the fourth spacing.

4. The double-layer plate type pet magnetic hyperthermia treatment device according to claim 1, characterized in that: Also includes: The cooling components are respectively arranged on the side of the first treatment plate and the second treatment plate facing away from each other; the cooling component is in contact with the surface of the first treatment plate facing away from the second treatment plate; the cooling component is in contact with the surface of the second treatment plate facing away from the first treatment plate.

5. The double-layer plate type pet magnetic hyperthermia treatment device according to claim 4, characterized in that: The cooling assembly comprises: A receiving frame, comprising a bottom plate, side plates protruding from an edge of the bottom plate, and a connecting plate, wherein the side plates and the bottom plate enclose a receiving cavity, and the connecting plate is disposed on a side of the side plate away from the receiving cavity and connected to the first treatment plate or the second treatment plate; A mold is arranged in the accommodating cavity, and a reflux groove is provided on a side of the mold away from the bottom plate; The cooling element is adapted to be placed in the reflux groove.

6. The double-layer plate type pet magnetic hyperthermia treatment device according to claim 5, characterized in that: The cooling assembly further comprises: a first conductive member, disposed on the side plate, with one end extending to the outside of the accommodating frame and the other end communicating with the accommodating cavity and the cooling member; One end of the second connecting member is connected to the mold, and the other end passes through the side plate and extends to the outside of the accommodating frame.

7. The double-layer plate type pet magnetic hyperthermia treatment device according to claim 4, characterized in that: The host further includes a control component, which is electrically connected to the sliding plate and is used to drive the sliding plate to move in a direction, displacement or speed relative to the supporting platform.

8. The double-layer plate type pet magnetic hyperthermia treatment device according to claim 7, characterized in that: Also included is a lifting assembly, the lifting assembly being disposed between a side of the cooling assembly facing away from the first treatment plate and the bracket, or the lifting assembly being disposed between a side of the cooling assembly facing away from the second treatment plate and the supporting platform; The control component is connected to the lifting component, and the control component is used to control the lifting component to drive the cooling mechanism and the first treatment plate to move, and to control the lifting component to drive the cooling component and the second treatment plate to move.

9. The double-layer plate type pet magnetic hyperthermia treatment device according to claim 7, characterized in that: The host also includes: A power supply component is arranged on the supporting platform, the first treatment plate and / or the second treatment plate are connected to the power supply component and are used to provide alternating current to the first treatment plate and / or the second treatment plate; the control component is electrically connected to the power supply component and is used to control the intensity or frequency of the alternating current.

10. The double-layer plate type pet magnetic hyperthermia treatment device according to claim 1, characterized in that: The sliding plate includes a first plate body and a second plate body that are arranged in contact with each other, the second plate body is arranged on a side of the first plate body close to the supporting platform, the two end portions of the first plate body are respectively protruded along the first direction at the two end portions of the second plate body, and the second plate body is connected to the side of the second treatment plate close to the first treatment plate.

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