A cell detection sampling device
By designing a cell detection sampling device with sealing, flushing, and disinfection mechanisms, the problem of contamination of culture devices during cell sampling was solved, achieving high-precision sampling and detection.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SUZHOU TUOWEI BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-04-01
- Publication Date
- 2026-05-15
AI Technical Summary
Existing technologies can easily lead to contamination of cell culture devices by foreign bacteria during cell sampling, affecting the accuracy of test results.
A cell detection sampling device was designed, comprising a blocking mechanism, a flushing mechanism, and a disinfection mechanism. The drainage tube is blocked and sealed by raising and lowering the blocking block. Combined with the flushing and disinfection mechanisms, the device ensures that the incubator has less contact with the outside world during the sampling process, and cleans and disinfects the drainage tube to avoid contamination.
It effectively reduces the possibility of cell contamination in the cell culture incubator, improves the precision and accuracy of sampling and testing, and ensures that the drainage tube remains clean after each sampling, avoiding any impact on the results of the next sampling.
Smart Images

Figure CN120505180B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of cell detection and sampling technology, specifically a cell detection and sampling device. Background Technology
[0002] Hyperthermia is clinically known as a green therapy for cancer treatment. This is mainly because this treatment method can control the growth and proliferation of tumors, kill tumor cells, and shrink tumors. Heating tumor cells is a common method for studying tumor cells. In the research process, it is necessary to sample tumor cells at different temperatures and study the tumor's response at different temperatures.
[0003] In the existing technology, when sampling cells, the cell culture device is usually turned on and then a sampling probe is used to take the sample. During this process, the cell culture device needs to be turned on, which can easily cause foreign bacteria to enter the cell culture device.
[0004] To address this issue, Chinese Patent Publication No. CN108753592B discloses a heating device for aseptic sampling of tumor cells. This device uses a liftable drainage tube within a cell culture dish. Sampling is achieved when the drainage tube is removed from the dish. While this method eliminates the need to open the culture dish, the drainage tube comes into contact with air when it extends outside, preventing the tube from accumulating airborne bacteria. When the drainage tube re-enters the culture dish, it contaminates the cells, affecting normal cell culture and subsequent sampling, ultimately impacting test results. To address this problem, a cell detection and sampling device is proposed. Summary of the Invention
[0005] The purpose of this invention is to provide a cell detection and sampling device to solve the problems mentioned in the background art.
[0006] To achieve the above objectives, the present invention provides the following technical solution:
[0007] A cell detection and sampling device includes a base, a detection platform and a vertical plate. The detection platform is fixedly installed on the top of the base, the vertical plate is fixedly installed on one side of the detection platform, an incubator is installed above the detection platform, and the device also includes a drainage tube, a sealing mechanism, a rinsing mechanism and a disinfection mechanism.
[0008] The drainage tube is integrally molded and installed at the bottom of the incubator;
[0009] The blocking mechanism includes a blocking block, a lifting assembly, and a connecting assembly. The blocking block is located inside the incubator, and the bottom end of the blocking block is inserted into the top end of the drainage tube. The connecting assembly is slidably mounted on the top of the incubator, and the bottom end of the connecting assembly is fixedly connected to the blocking block. The lifting assembly is located between the vertical plate and the connecting assembly.
[0010] The flushing mechanism includes an annular channel, a transmission assembly, an extraction assembly, an output assembly, and several output channels. The annular channel is located inside the sealing block, and several output channels are equidistantly arranged inside the sealing block. One end of each output channel is connected to the annular channel. The output assembly is located above the detection platform, and the output end of the output assembly is connected to the annular channel.
[0011] The disinfection mechanism includes two sealing covers, two electric heating blocks, and a telescopic assembly. The two sealing covers are symmetrically arranged on both sides of the drainage tube, and each electric heating block is installed inside one of the sealing covers.
[0012] As a further embodiment of the present invention: the connecting assembly includes a lifting ring, two connecting blocks and multiple lifting rods. The lifting ring is located above the incubator, and the multiple lifting rods are equidistantly slidably arranged at the top of the incubator. Both ends of each lifting rod are fixedly connected to the lifting ring and the sealing block, respectively. The two connecting blocks are symmetrically fixed on both sides of the lifting ring.
[0013] As a further embodiment of the present invention: the lifting assembly includes a lifting frame, a first cylinder, two slide grooves, multiple first guide rods, multiple limit blocks and multiple first springs. Both slide grooves are opened on the surface of the vertical plate. The lifting frame is located above the lifting ring. One end of the lifting frame is slidably disposed in the two slide grooves. The first cylinder is fixed on one side of the vertical plate. The output end of the first cylinder is fixedly connected to one end of the lifting frame.
[0014] Each first guide rod is slidably mounted on the lifting frame. The top end of each first guide rod is fixedly connected to a limiting block. The bottom ends of every two first guide rods are fixedly connected to a connecting block. Each first spring is sleeved on the outside of a first guide rod. Both ends of each first spring are respectively connected to the lifting frame and the connecting block.
[0015] As a further embodiment of the present invention: a storage box is installed at the top of the detection platform, and an inlet pipe is connected to the bottom of the storage box. A storage cylinder is installed on one side of the incubator and mounted on the detection platform. The other end of the inlet pipe is connected to the storage cylinder. An outlet pipe is installed at the end of the storage cylinder near the inlet pipe. A one-way valve is installed on both the outlet pipe and the inlet pipe. An extraction component is installed at the end of the storage cylinder away from the outlet pipe. An output component is located between the outlet pipe and the annular channel.
[0016] As a further embodiment of the present invention: the transmission assembly includes an L-shaped rod, a pressure rod, a guide rail, a rack, a top rod, a top plate, a stop block, a limiting plate, a second guide rod, a second spring, and a gear. The guide rail is fixed to the top of the incubator. The rack is slidably disposed inside the guide rail. The top end of the rack is fixedly connected to one end of the top rod, and the other end of the top rod is fixedly connected to the top plate. The stop block is fixedly installed on the top of the top plate. The limiting plate is fixed to one side of the guide rail. The second guide rod is slidably disposed on the limiting plate. The top end of the second guide rod is fixedly connected to the top plate. The second spring is sleeved on the outside of the second guide rod, and the two ends of the second spring are respectively connected to the top plate and the limiting plate.
[0017] The L-shaped rod is fixed at the top of the lifting frame, the pressure rod is located above the abutment block, and the top of the pressure rod is fixedly connected to the end of the L-shaped rod away from the lifting frame. The gear is rotated at the top of the incubator, and the gear meshes with the rack.
[0018] As a further embodiment of the present invention: the extraction assembly includes a push rod, a push plate, a turntable, a hinge rod, and a synchronization component. The push rod is slidably disposed at the end of the storage cylinder away from the water outlet pipe. The push plate is slidably disposed inside the storage cylinder. One end of the push rod is fixedly connected to the push plate. The turntable is rotatably disposed above the detection platform. One end of the hinge rod is hinged to the end of the push rod away from the push plate. The other end of the hinge rod is hinged to the surface of the turntable. The synchronization component is located between the turntable and the gear.
[0019] As a further embodiment of the present invention: the synchronization component includes a transmission belt and two pulleys, the two pulleys being fixed to one side of the turntable and the gear respectively, and the transmission belt being sleeved on the outside of the two pulleys.
[0020] As a further aspect of the present invention: the output component includes a hose, an annular tube, and multiple strip channels. Each strip channel is opened inside a lifting rod, and the bottom end of each strip channel is connected to the annular channel. The annular tube is installed above the lifting ring, the top end of each lifting rod is connected to the surface of the annular tube, and the top end of each strip channel is connected to the interior of the annular tube. One end of the hose is connected to the annular tube, and the other end of the hose is connected to the water outlet pipe.
[0021] As a further embodiment of the present invention: the telescopic assembly includes a rotating rod, a second cylinder, two guide bars, two moving blocks, two connecting rods, and two connecting frames. The two guide bars are fixed to the bottom end of the testing platform, and each moving block is slidably mounted on the two guide bars. The second cylinder is mounted on the bottom end of the testing platform, and the output end of the second cylinder is connected to one of the moving blocks. The middle part of the rotating rod is rotatably mounted on the bottom end of the testing platform via a rotating shaft. The two connecting rods are respectively hinged to the two ends of the rotating rod, and the other end of each connecting rod is hinged to a moving block. The two connecting frames are respectively fixed to the sides of the two sealing covers that are far apart from each other, and each connecting frame is mounted on a moving block.
[0022] As a further aspect of the present invention: a fixing frame is provided below the drainage tube, and the pressure rod is detachably installed on the top of the base.
[0023] Compared with the prior art, the beneficial effects of the present invention are:
[0024] 1. A cell detection sampling device of the present invention, by setting a sealing mechanism, can seal the drainage tube by setting a sealing block. When sampling is required, the lifting component and the connecting component drive the sealing block to move upward, release the sealing of the drainage tube, and use the drainage tube to drain the sample to realize sampling. During the sampling process, the possibility of contact between the inside of the incubator and the outside world can be effectively reduced, the possibility of cell contamination in the incubator can be reduced, and the accuracy of sampling and detection can be improved.
[0025] 2. A cell detection sampling device of the present invention, by setting a rinsing mechanism, allows rinsing water inside the storage tank to enter and exit the storage cylinder during sampling as the sealing block moves upward. After each sampling is completed, the sealing block seals the drainage tube, and the rinsing water inside the storage cylinder can flow out through several output channels on the sealing block, allowing the rinsing water to flow to the inner wall of the drainage tube, thereby rinsing the inner wall of the drainage tube after sampling, avoiding the influence of residual sample on the inner wall of the drainage tube on the next sampling, and improving the detection accuracy.
[0026] 3. The cell detection sampling device of the present invention, through the set disinfection mechanism, after the internal rinsing of the drainage tube is completed, uses the telescopic component to drive the two sealing covers to come closer together, wrapping the drainage tube in the two sealing covers to achieve a sealing effect on the drainage tube. The space inside the two sealing covers is heated by the electric heating block, which on the one hand dries the rinsing water on the inner wall of the drainage tube, and on the other hand, achieves high-temperature sterilization of the drainage tube during heating, so as to avoid the drainage tube being contaminated with bacteria in the air and causing contamination of the sample taken next time.
[0027] 4. The cell detection sampling device of the present invention, combined with a rinsing mechanism and a disinfection mechanism, can clean and disinfect the drainage tube after each sampling, so that the drainage tube is in a clean state when sampling next, avoiding contamination of the next batch of samples by the drainage tube, and improving the detection accuracy of the samples.
[0028] 5. A cell detection sampling device of the present invention, through a transmission component, when sampling is required, the blocking block moves upward to release the anti-blocking of the drainage tube. At this time, under the action of the transmission component, flushing water enters the interior of the storage cylinder. After sampling is completed, the blocking block moves back into the interior of the drainage tube to block the drainage tube. At this time, under the action of the transmission component, the flushing water inside the storage cylinder can be squeezed out to flush the interior of the drainage tube. The synchronization is high and meets the usage requirements. Attached Figure Description
[0029] Figure 1 This is a schematic diagram of the structure of the present invention. Figure 1 .
[0030] Figure 2 For the present invention Figure 1 A magnified structural diagram of part A in the middle.
[0031] Figure 3 This is a schematic diagram of the structure of the present invention. Figure 2 .
[0032] Figure 4 For the present invention Figure 3 A magnified structural diagram of part B.
[0033] Figure 5 This is a front view of the present invention.
[0034] Figure 6 This is a schematic cross-sectional view of the incubator in this invention.
[0035] Figure 7 For the present invention Figure 6 A magnified structural diagram of section C.
[0036] Figure 8 This is a schematic diagram of the cross-sectional structure of the storage cylinder in this invention.
[0037] Figure 9 This is a schematic diagram of the lifting frame in this invention.
[0038] Figure 10 This is a schematic diagram of the sealing block in this invention.
[0039] Figure 11 This is a schematic diagram of the structure of the second cylinder in this invention.
[0040] Figure 12 For the present invention Figure 11 A magnified structural diagram of part D in the middle.
[0041] Figure 13 This is a schematic diagram of the sealing cover in this invention.
[0042] The components include: 11. Base; 12. Testing table; 13. Vertical plate; 14. Clearance groove; 15. Incubator; 16. Drainage tube; 17. Sealing block; 18. Lifting rod; 19. Lifting ring; 20. Connecting block; 21. First guide rod; 22. Lifting frame; 23. Limiting block; 24. First spring; 25. L-shaped rod; 26. Pressure rod; 27. Guide rail; 28. Rack; 29. Top rod; 30. Top plate; 31. Abutment block; 32. Limiting plate; 33. Second guide rod; 34. Second spring; 35. Gear; 36. Pulley; 7. Drive belt; 38. Turntable; 39. Hinge rod; 40. Push rod; 41. Push plate; 42. Storage cylinder; 43. Water outlet pipe; 44. Water inlet pipe; 45. Storage box; 46. Through hole; 47. Hose; 48. Ring pipe; 49. Strip channel; 50. Ring channel; 51. Output channel; 52. First cylinder; 53. Slide groove; 54. Second cylinder; 55. Sealing cover; 56. Electric heating block; 57. Connecting frame; 58. Guide bar; 59. Moving block; 60. Rotating rod; 61. Connecting rod; 62. Fixed frame. Detailed Implementation
[0043] The principles and features of the present invention are described below with reference to the accompanying drawings. The examples given are only for explaining the present invention and are not intended to limit the scope of the present invention.
[0044] The present invention provides the following preferred embodiments:
[0045] Example 1, as Figures 1-13 As shown, a cell detection and sampling device includes a base 11, a detection platform 12, and a vertical plate 13. The detection platform 12 is fixedly installed on the top of the base 11, and the vertical plate 13 is fixedly installed on one side of the detection platform 12. An incubator 15 is installed above the detection platform 12. The incubator 15 is a device specifically used for cell, tissue, and bacterial culture. The incubator 15 is existing technology and will not be described in detail here. It should be noted that, in order to facilitate the study of tumor cells, the incubator 15 is equipped with a temperature control system for heating the cells. Heating tumor cells is a common method for studying tumor cells. During the research process, tumor cell samples at different temperatures are sampled to facilitate the study of the tumor's response at different temperatures. The device also includes a drainage tube 16, a sealing mechanism, a flushing mechanism, and a disinfection mechanism.
[0046] The drainage tube 16 is integrally formed and set at the bottom of the incubator 15. It should be noted that the detection table 12 is provided with a relief groove 14 for the drainage tube 16 to pass through.
[0047] The blocking mechanism includes a blocking block 17, a lifting assembly, and a connecting assembly. The blocking block 17 is located inside the incubator 15, and the bottom end of the blocking block 17 is inserted into the top end of the drainage tube 16. The connecting assembly is slidably disposed at the top end of the incubator 15, and the bottom end of the connecting assembly is fixedly connected to the blocking block 17. The lifting assembly is located between the vertical plate 13 and the connecting assembly.
[0048] The blocking block 17 can block the drainage tube 16. When sampling is required, the sampling tube is first placed in the fixed frame 62. The lifting component and the connecting component can drive the blocking block 17 to move upward, thereby releasing the blockage of the drainage tube 16. The telescopic component can drive the two sealing covers 55 to move away from each other, so that the drainage tube 16 can smoothly drain. The drainage tube 16 can be used to drain the sample, so that the sample can enter the sampling tube below to achieve sampling.
[0049] The flushing mechanism includes an annular channel 50, a transmission assembly, an extraction assembly, an output assembly, and several output channels 51. The annular channel 50 is located inside the sealing block 17. Several output channels 51 are equidistantly arranged inside the sealing block 17. One end of each output channel 51 is connected to the annular channel 50. The output assembly is located above the detection table 12, and the output end of the output assembly is connected to the annular channel 50.
[0050] The disinfection mechanism includes two sealing covers 55, two electric heating blocks 56, and a telescopic component. The two sealing covers 55 are symmetrically arranged on both sides of the drainage tube 16. Each electric heating block 56 is installed inside one sealing cover 55. The telescopic component can drive the two sealing covers 55 to move closer to each other, wrapping the drainage tube 16 in the two sealing covers 55, thereby achieving a sealing effect on the drainage tube 16.
[0051] like Figures 1-13 As shown, the connecting assembly includes a lifting ring 19, two connecting blocks 20 and multiple lifting rods 18. The lifting ring 19 is located above the incubator 15. The multiple lifting rods 18 are equidistantly slidably arranged at the top of the incubator 15. Both ends of each lifting rod 18 are fixedly connected to the lifting ring 19 and the sealing block 17, respectively. The two connecting blocks 20 are symmetrically fixed on both sides of the lifting ring 19.
[0052] When the lifting assembly is working, it can drive the two connecting blocks 20 to move. The two connecting blocks 20 can drive the lifting ring 19 to move. When the lifting ring 19 moves, multiple lifting rods 18 can slide on the incubator 15, thereby driving the sealing block 17 to move.
[0053] like Figures 1-13As shown, the lifting assembly includes a lifting frame 22, a first cylinder 52, two slide grooves 53, multiple first guide rods 21, multiple limit blocks 23, and multiple first springs 24. Both slide grooves 53 are formed on the surface of the vertical plate 13. The lifting frame 22 is located above the lifting ring 19. One end of the lifting frame 22 is slidably disposed in the two slide grooves 53. The first cylinder 52 is fixed to one side of the vertical plate 13. The output end of the first cylinder 52 is fixedly connected to one end of the lifting frame 22. The first cylinder 52 can drive the lifting frame 22 to slide in the two slide grooves 53.
[0054] Each first guide rod 21 is slidably mounted on the lifting frame 22. The top end of each first guide rod 21 is fixedly connected to a limiting block 23. The bottom ends of every two first guide rods 21 are fixedly connected to a connecting block 20. Each first spring 24 is sleeved on the outside of a first guide rod 21. Both ends of each first spring 24 are respectively connected to the lifting frame 22 and the connecting block 20.
[0055] In the initial state, the bottom end of the blocking block 17 is inserted into the inside of the drainage tube 16, and the first spring 24 is in a compressed state;
[0056] When sampling is required, the controller controls the first cylinder 52 to work. The first cylinder 52 can drive the lifting frame 22 to slide upward inside the two slide grooves 53. Since the first spring 24 is initially in a compressed state, when the lifting frame 22 slides upward, the first spring 24 gradually extends. As the lifting frame 22 continues to move upward, when the first spring 24 returns to its natural state, the top of the lifting frame 22 contacts the bottom of the first guide rod 21. As the lifting frame 22 continues to move, the lifting frame 22 can drive the connecting block 20 to move upward through the limiting block 23 and the first guide rod 21. The connecting block 20 can drive the sealing block 17 to move upward through the lifting ring 19 and multiple lifting rods 18, releasing the blockage of the drainage pipe 16 and using the drainage pipe 16 to achieve drainage, thereby realizing sampling.
[0057] like Figures 1-13 As shown, a storage box 45 is installed at the top of the detection platform 12, and an inlet pipe 44 is connected to the bottom of the storage box 45. A storage cylinder 42 is installed on one side of the incubator 15 on the detection platform 12. The other end of the inlet pipe 44 is connected to the storage cylinder 42. An outlet pipe 43 is installed at the end of the storage cylinder 42 near the inlet pipe 44. A one-way valve is installed on both the outlet pipe 43 and the inlet pipe 44. The extraction component is installed at the end of the storage cylinder 42 away from the outlet pipe 43. The output component is located between the outlet pipe 43 and the annular channel 50.
[0058] The storage tank 45 contains flushing water for cleaning the inner wall of the drainage tube 16.
[0059] like Figures 1-13As shown, the transmission assembly includes an L-shaped rod 25, a pressure rod 26, a guide rail 27, a rack 28, a top rod 29, a top plate 30, a stop block 31, a limiting plate 32, a second guide rod 33, a second spring 34, and a gear 35. The guide rail 27 is fixed to the top of the incubator 15. The rack 28 is slidably disposed inside the guide rail 27. The top end of the rack 28 is fixedly connected to one end of the top rod 29. The other end of the top rod 29 is fixedly connected to the top plate 30. The stop block 31 is fixedly installed on the top of the top plate 30. The limiting plate 32 is fixed to one side of the guide rail 27. The second guide rod 33 is slidably disposed on the limiting plate 32. The top end of the second guide rod 33 is fixedly connected to the top plate 30. The second spring 34 is sleeved on the outside of the second guide rod 33. The two ends of the second spring 34 are respectively connected to the top plate 30 and the limiting plate 32.
[0060] L-shaped rod 25 is fixed to the top of lifting frame 22, pressure rod 26 is located above abutment block 31, and the top of pressure rod 26 is fixedly connected to the end of L-shaped rod 25 away from lifting frame 22. Gear 35 is rotatably mounted on the top of incubator 15. Specifically, the top of incubator 15 is fixed with a first mounting plate, and gear 35 is rotatably mounted on the first mounting plate. Gear 35 meshes with rack 28.
[0061] In the initial state, the bottom end of the pressure rod 26 is in contact with the top end of the abutment block 31, and the second spring 34 is in a compressed state;
[0062] When it is necessary to unblock the drainage tube 16, that is, when the lifting frame 22 moves upward, the lifting frame 22 can drive the L-shaped rod 25 and the pressure rod 26 on the L-shaped rod 25 to move upward. Since the second spring 34 is initially in a compressed state, when the pressure rod 26 moves upward, it can drive the top plate 30 to move upward under the action of the second spring 34. The top plate 30 drives the rack 28 to slide upward inside the guide rail 27 through the top rod 29. When the rack 28 moves upward, it can drive the gear 35 to rotate.
[0063] like Figures 1-13 As shown, the extraction assembly includes a push rod 40, a push plate 41, a turntable 38, a hinge rod 39, and a synchronization component. The push rod 40 is slidably disposed at the end of the storage cylinder 42 away from the water outlet pipe 43. The push plate 41 slides inside the storage cylinder 42. One end of the push rod 40 is fixedly connected to the push plate 41. The turntable 38 is rotatably disposed above the detection platform 12. Specifically, a second mounting plate is fixed above the detection platform 12, and the turntable 38 is rotatably disposed on the second mounting plate. One end of the hinge rod 39 is hinged to the end of the push rod 40 away from the push plate 41, and the other end of the hinge rod 39 is hinged to the surface of the turntable 38. The synchronization component is located between the turntable 38 and the gear 35.
[0064] In the initial state, the push plate 41 is located inside the storage cylinder 42 on the side close to the water outlet pipe 43. It should be noted that a through hole 46 is opened on the surface of the storage cylinder 42 away from the water outlet pipe 43.
[0065] like Figures 1-13 As shown, the synchronization component includes a transmission belt 37 and two pulleys 36. The two pulleys 36 are fixed to one side of the turntable 38 and the gear 35, respectively. That is, one pulley 36 is coaxially fixedly connected to the turntable 38, and the other pulley 36 is coaxially fixedly connected to the gear 35. The transmission belt 37 is sleeved on the outside of the two pulleys 36.
[0066] When the rack 28 moves upward, it can drive the gear 35 to rotate. The gear 35 can drive the turntable 38 to rotate through the transmission belt 37 and two pulleys 36. Under the action of the hinge rod 39, when the turntable 38 rotates, it can drive the push rod 40 to slide on the storage cylinder 42 away from the water outlet pipe 43, so that the push plate 41 can move away from the water outlet pipe 43. At this time, the rinsing water inside the storage box 45 can enter the storage cylinder 42 through the water inlet pipe 44 for storage.
[0067] After sampling is completed, the sampling tube containing the sample is removed from the fixing frame 62. Then, the controller controls the first cylinder 52 to work. The first cylinder 52 can drive the lifting frame 22 to slide downward inside the two slide grooves 53. When the lifting frame 22 moves, it can drive the L-shaped rod 25 and the pressure rod 26 on the L-shaped rod 25 to move downward. When the lifting frame 22 moves, it can drive the connecting block 20 to move downward through the first guide rod 21, the limiting block 23, and the first spring 24. The connecting block 20 drives the sealing block 17 to move downward through the lifting ring 19 and multiple lifting rods 18, so that the sealing block 17 can move back into the interior of the drainage tube 16 to seal the drainage tube 16. At this time, the pressure rod 26 contacts the abutment block 31.
[0068] After the blocking block 17 blocks the drainage pipe 16, the first cylinder 52 continues to work, causing the lifting frame 22 to continue to move down, at which time the first spring 24 is compressed;
[0069] As the lifting frame 22 continues to move downward, it can push the rack 28 to move downward inside the guide rail 27 through the L-shaped rod 25 and the pressure rod 26. At this time, the second spring 34 is compressed. When the rack 28 moves downward, it can drive the gear 35 to rotate in the opposite direction. The gear 35 drives the turntable 38 to rotate in the opposite direction through the transmission belt 37 and two pulleys 36. Under the action of the hinge rod 39, it can drive the push rod 40 and the push plate 41 to move in the opposite direction, so that the rinsing water stored inside the storage cylinder 42 can be squeezed out through the water outlet pipe 43.
[0070] like Figures 1-13As shown, the output assembly includes a hose 47, an annular tube 48, and multiple strip channels 49. Each strip channel 49 is opened inside a lifting rod 18. The bottom end of each strip channel 49 is connected to an annular channel 50. The annular tube 48 is installed above the lifting ring 19. The top end of each lifting rod 18 is connected to the surface of the annular tube 48. The top end of each strip channel 49 is connected to the interior of the annular tube 48. One end of the hose 47 is connected to the annular tube 48, and the other end of the hose 47 is connected to the outlet pipe 43.
[0071] The flushing water squeezed out through the outlet pipe 43 enters the interior of the hose 47, and then passes through the annular pipe 48 and multiple strip channels 49, so that the flushing water is collected in the annular channel 50. Finally, the flushing water flows out through several outlet channels 51 to the inner wall of the drainage pipe 16, thereby flushing the inner wall of the drainage pipe 16 after sampling.
[0072] That is, after each sampling is completed, the blocking block 17 can block the drainage tube 16. After the blocking block 17 blocks the drainage tube 16, the drainage tube 16 can be cleaned and disinfected, so that the drainage tube 16 can be in a clean state when sampling next, avoiding the drainage tube 16 from contaminating the next batch of samples, which is conducive to improving the detection accuracy of the samples.
[0073] like Figures 1-13 As shown, the telescopic assembly includes a rotating rod 60, a second cylinder 54, two guide bars 58, two moving blocks 59, two connecting rods 61, and two connecting frames 57. The two guide bars 58 are fixed to the bottom of the testing table 12. Each moving block 59 is slidably mounted on the two guide bars 58. The second cylinder 54 is mounted on the bottom of the testing table 12. The output end of the second cylinder 54 is connected to one of the moving blocks 59. The middle part of the rotating rod 60 is rotatably mounted on the bottom of the testing table 12 via a rotating shaft. The two connecting rods 61 are respectively hinged to the two ends of the rotating rod 60. The other end of each connecting rod 61 is hinged to a moving block 59. The two connecting frames 57 are respectively fixed to the two sealing covers 55 on opposite sides. Each connecting frame 57 is mounted on a moving block 59.
[0074] Before sampling is required, the controller first controls the second cylinder 54 to work. The second cylinder 54 drives the moving block 59 connected to the output end of the second cylinder 54 to move. Under the action of the rotating rod 60 and the two connecting rods 61, it can drive another moving block 59 to move, so that the two moving blocks 59 can move in a direction away from each other. At this time, the two connecting frames 57 can drive the two sealing covers 55 to move in a direction away from each other, so that the drainage tube 16 can smoothly achieve drainage.
[0075] After the drainage tube 16 is rinsed inside, the telescopic component can be used to move the two sealing covers 55 closer together, wrapping the drainage tube 16 in the two sealing covers 55 to achieve a sealing effect. The electric heating block 56 heats the space inside the two sealing covers 55, which on the one hand dries the rinsing water on the inner wall of the drainage tube 16, and on the other hand, the high temperature sterilization of the drainage tube 16 can be achieved during heating, so as to prevent the drainage tube 16 from being contaminated by bacteria in the air and causing contamination of the next sample taken out.
[0076] like Figures 1-13 As shown, a fixing frame 62 is provided below the drainage tube 16, and the pressure rod 26 is detachably installed on the top of the base 11. Specifically, the fixing frame 62 is a test tube rack.
[0077] The specific working process of this invention is as follows:
[0078] When sampling is required, the sampling tube is first placed in the fixed frame 62. The controller first controls the second cylinder 54 to work. The second cylinder 54 drives the moving block 59 connected to the output end of the second cylinder 54 to move. Under the action of the rotating rod 60 and the two connecting rods 61, it can drive another moving block 59 to move, so that the two moving blocks 59 can move in a direction away from each other. At this time, the two connecting frames 57 can drive the two sealing covers 55 to move in a direction away from each other, so that the drainage tube 16 can smoothly achieve drainage.
[0079] The controller controls the first cylinder 52 to work. The first cylinder 52 can drive the lifting frame 22 to slide upward inside the two slide grooves 53. Since the first spring 24 is initially in a compressed state, when the lifting frame 22 slides upward, the first spring 24 gradually extends. As the lifting frame 22 continues to move upward, when the first spring 24 returns to its natural state, the top of the lifting frame 22 contacts the bottom of the first guide rod 21. As the lifting frame 22 continues to move, the lifting frame 22 can drive the connecting block 20 to move upward through the limiting block 23 and the first guide rod 21. The connecting block 20 can drive the sealing block 17 to move upward through the lifting ring 19 and multiple lifting rods 18, thereby releasing the blockage of the drainage pipe 16 and realizing drainage through the drainage pipe 16, thus realizing sampling.
[0080] When the lifting frame 22 moves upward, it can drive the L-shaped rod 25 and the pressure rod 26 on the L-shaped rod 25 to move upward. Since the second spring 34 is initially in a compressed state, when the pressure rod 26 moves upward, it can drive the top plate 30 to move upward under the action of the second spring 34. The top plate 30 drives the rack 28 to slide upward inside the guide rail 27 through the push rod 29. When the rack 28 moves upward, it can drive the gear 35 to rotate. The gear 35 can drive the turntable 38 to rotate through the transmission belt 37 and two pulleys 36. Under the action of the hinge rod 39, when the turntable 38 rotates, it can drive the push rod 40 to slide on the storage cylinder 42 away from the water outlet pipe 43, so that the push plate 41 can move away from the water outlet pipe 43. At this time, the flushing water inside the storage box 45 can enter the storage cylinder 42 through the water inlet pipe 44 for storage.
[0081] After sampling is completed, the sampling tube containing the sample is removed from the fixing frame 62. Then, the controller controls the first cylinder 52 to work. The first cylinder 52 can drive the lifting frame 22 to slide downward inside the two slide grooves 53. When the lifting frame 22 moves, it can drive the L-shaped rod 25 and the pressure rod 26 on the L-shaped rod 25 to move downward. When the lifting frame 22 moves, it can drive the connecting block 20 to move downward through the first guide rod 21, the limiting block 23, and the first spring 24. The connecting block 20 drives the sealing block 17 to move downward through the lifting ring 19 and multiple lifting rods 18, so that the sealing block 17 can move back into the interior of the drainage tube 16 to seal the drainage tube 16. At this time, the pressure rod 26 contacts the abutment block 31.
[0082] After the blocking block 17 blocks the drainage pipe 16, the first cylinder 52 continues to work, causing the lifting frame 22 to continue to move down, at which time the first spring 24 is compressed;
[0083] As the lifting frame 22 continues to move downward, it can push the rack 28 to move downward inside the guide rail 27 through the L-shaped rod 25 and the pressure rod 26. At this time, the second spring 34 is compressed. When the rack 28 moves downward, it can drive the gear 35 to rotate in the opposite direction. The gear 35 drives the turntable 38 to rotate in the opposite direction through the transmission belt 37 and two pulleys 36. Under the action of the hinge rod 39, it can drive the push rod 40 and the push plate 41 to move in the opposite direction, so that the flushing water stored inside the storage cylinder 42 can be squeezed out through the water outlet pipe 43. The flushing water squeezed out through the water outlet pipe 43 enters the interior of the hose 47, and then through the annular pipe 48 and multiple strip channels 49, so that the flushing water is collected in the annular channel 50. Finally, the flushing water flows out through several output channels 51 to the inner wall of the drainage pipe 16, realizing the flushing of the inner wall of the sampling drainage pipe 16.
[0084] That is, after each sampling is completed, the blocking block 17 can block the drainage tube 16. After the blocking block 17 blocks the drainage tube 16, the drainage tube 16 can be cleaned and disinfected, so that the drainage tube 16 can be in a clean state when sampling next, avoiding the drainage tube 16 from contaminating the next batch of samples, which is conducive to improving the detection accuracy of the samples.
[0085] After the drainage tube 16 is rinsed inside, the telescopic component can be used to move the two sealing covers 55 closer together, wrapping the drainage tube 16 in the two sealing covers 55 to achieve a sealing effect. The electric heating block 56 heats the space inside the two sealing covers 55, which on the one hand dries the rinsing water on the inner wall of the drainage tube 16, and on the other hand, the high temperature sterilization of the drainage tube 16 can be achieved during heating, so as to prevent the drainage tube 16 from being contaminated by bacteria in the air and causing contamination of the next sample taken out.
[0086] The beneficial effects of the present invention are specifically reflected in the fact that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.
Claims
1. A cell detection and sampling device, comprising a base (11), a detection platform (12), and a vertical plate (13), wherein the detection platform (12) is fixedly installed on the top of the base (11), the vertical plate (13) is fixedly installed on one side of the detection platform (12), and an incubator (15) is installed above the detection platform (12), characterized in that, It also includes a drainage tube (16), a sealing mechanism, a flushing mechanism, and a disinfection mechanism; The drainage tube (16) is integrally formed and installed at the bottom of the incubator (15); The sealing mechanism includes a sealing block (17), a lifting assembly and a connecting assembly. The sealing block (17) is located inside the incubator (15), and the bottom end of the sealing block (17) is inserted into the top end of the drainage tube (16). The connecting assembly is slidably disposed at the top end of the incubator (15), and the bottom end of the connecting assembly is fixedly connected to the sealing block (17). The lifting assembly is located between the vertical plate (13) and the connecting assembly. The flushing mechanism includes an annular channel (50), a transmission assembly, an extraction assembly, an output assembly, and several output channels (51). The annular channel (50) is located inside the sealing block (17), and several output channels (51) are equidistantly arranged inside the sealing block (17). One end of each output channel (51) is connected to the annular channel (50). The output assembly is located above the detection table (12), and the output end of the output assembly is connected to the annular channel (50). The disinfection mechanism includes two sealing covers (55), two electric heating blocks (56) and a telescopic assembly. The two sealing covers (55) are symmetrically arranged on both sides of the drainage tube (16), and each electric heating block (56) is installed inside a sealing cover (55). The connecting assembly includes a lifting ring (19), two connecting blocks (20) and multiple lifting rods (18). The lifting ring (19) is located above the incubator (15). Multiple lifting rods (18) are equidistantly slidably arranged at the top of the incubator (15). Both ends of each lifting rod (18) are fixedly connected to the lifting ring (19) and the sealing block (17) respectively. The two connecting blocks (20) are symmetrically fixed on both sides of the lifting ring (19). The lifting assembly includes a lifting frame (22), a first cylinder (52), two slides (53), multiple first guide rods (21), multiple limit blocks (23) and multiple first springs (24). The two slides (53) are both opened on the surface of the vertical plate (13). The lifting frame (22) is located above the lifting ring (19). One end of the lifting frame (22) is slidably set in the two slides (53). The first cylinder (52) is fixed on one side of the vertical plate (13). The output end of the first cylinder (52) is fixedly connected to one end of the lifting frame (22). Each first guide rod (21) is slidably mounted on the lifting frame (22). The top end of each first guide rod (21) is fixedly connected to a limiting block (23). The bottom ends of every two first guide rods (21) are fixedly connected to a connecting block (20). Each first spring (24) is sleeved on the outside of a first guide rod (21). Both ends of each first spring (24) are respectively connected to the lifting frame (22) and the connecting block (20). A storage box (45) is installed at the top of the testing platform (12). A water inlet pipe (44) is connected to the bottom of the storage box (45). A storage cylinder (42) is installed on one side of the incubator (15) on the testing platform (12). The other end of the water inlet pipe (44) is connected to the storage cylinder (42). A water outlet pipe (43) is installed on the end of the storage cylinder (42) near the water inlet pipe (44). A one-way valve is installed on both the water outlet pipe (43) and the water inlet pipe (44). The extraction component is installed at the end of the storage cylinder (42) away from the water outlet pipe (43). The output component is located between the water outlet pipe (43) and the annular channel (50). The transmission assembly includes an L-shaped rod (25), a pressure rod (26), a guide rail (27), a rack (28), a top rod (29), a top plate (30), a stop block (31), a limiting plate (32), a second guide rod (33), a second spring (34), and a gear (35). The guide rail (27) is fixed to the top of the incubator (15). The rack (28) is slidably disposed inside the guide rail (27). The top end of the rack (28) is fixedly connected to one end of the top rod (29). 9) The other end is fixedly connected to the top plate (30), the abutment (31) is fixedly installed on the top of the top plate (30), the limiting plate (32) is fixed on one side of the guide rail (27), the second guide rod (33) is slidably set on the limiting plate (32), the top of the second guide rod (33) is fixedly connected to the top plate (30), the second spring (34) is sleeved on the outside of the second guide rod (33), and the two ends of the second spring (34) are respectively connected to the top plate (30) and the limiting plate (32); The L-shaped rod (25) is fixed at the top of the lifting frame (22), the pressure rod (26) is located above the abutment block (31), and the top of the pressure rod (26) is fixedly connected to the end of the L-shaped rod (25) away from the lifting frame (22). The gear (35) is rotatably set at the top of the incubator (15), and the gear (35) meshes with the rack (28).
2. The cell detection and sampling device according to claim 1, characterized in that, The extraction assembly includes a push rod (40), a push plate (41), a turntable (38), a hinge rod (39), and a synchronization component. The push rod (40) is slidably disposed at the end of the storage cylinder (42) away from the water outlet pipe (43). The push plate (41) is slidably disposed inside the storage cylinder (42). One end of the push rod (40) is fixedly connected to the push plate (41). The turntable (38) is rotatably disposed above the detection platform (12). One end of the hinge rod (39) is hinged to the end of the push rod (40) away from the push plate (41). The other end of the hinge rod (39) is hinged to the surface of the turntable (38). The synchronization component is located between the turntable (38) and the gear (35).
3. The cell detection and sampling device according to claim 2, characterized in that, The synchronization component includes a drive belt (37) and two pulleys (36). The two pulleys (36) are fixed to one side of the turntable (38) and the gear (35), respectively, and the drive belt (37) is sleeved on the outside of the two pulleys (36).
4. The cell detection and sampling device according to claim 3, characterized in that, The output assembly includes a hose (47), an annular pipe (48), and multiple strip channels (49). Each strip channel (49) is opened inside a lifting rod (18). The bottom end of each strip channel (49) is connected to the annular channel (50). The annular pipe (48) is installed above the lifting ring (19). The top end of each lifting rod (18) is connected to the surface of the annular pipe (48). The top end of each strip channel (49) is connected to the interior of the annular pipe (48). One end of the hose (47) is connected to the annular pipe (48), and the other end of the hose (47) is connected to the outlet pipe (43).
5. The cell detection and sampling device according to claim 4, characterized in that, The telescopic assembly includes a rotating rod (60), a second cylinder (54), two guide bars (58), two moving blocks (59), two connecting rods (61), and two connecting frames (57). The two guide bars (58) are fixed at the bottom of the testing table (12). Each moving block (59) is slidably mounted on the two guide bars (58). The second cylinder (54) is mounted at the bottom of the testing table (12). The output end of the second cylinder (54) is connected to one of the moving blocks (59). The middle part of the rotating rod (60) is rotatably mounted at the bottom of the testing table (12) via a rotating shaft. The two connecting rods (61) are respectively hinged to the two ends of the rotating rod (60). The other end of each connecting rod (61) is hinged to a moving block (59). The two connecting frames (57) are respectively fixed on the opposite sides of the two sealing covers (55). Each connecting frame (57) is mounted on a moving block (59).
6. The cell detection and sampling device according to claim 5, characterized in that, A fixing bracket (62) is provided below the drainage tube (16), and the pressure rod (26) is detachably installed on the top of the base (11).