Composition with peculiar smell removing effect
By mixing zinc ricinolate, lemon peel oil and glutathione in a specific proportion to make compositions in the form of spray, gel or cream, the problems of poor efficacy and safety risks of existing odor removal agents are solved, and significant odor removal effect and high safety are achieved.
Patent Information
- Application Number
- CN202510723268.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-30
- Publication Date
- 2025-08-29
AI Technical Summary
Commonly used odor deodorants on the market have poor efficacy and safety risks. People need a natural, significant and safe odor deodorant product.
Compositions in the form of spray, gel, lotion or cream are made by mixing zinc ricinolate, lemon peel oil and glutathione in a specific proportion, and the synergistic effect of its natural ingredients is significantly improved.
It significantly improves the odor removal effect, is safe and has good application prospects, and is suitable for home furnishings, industrial environments and other places.
Smart Images
Figure BDA0005429897220000061 
Figure BDA0005429897220000071 
Figure BDA0005429897220000081
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of biomedicine, and in particular relates to a composition with a deodorizing effect. Background Art
[0002] With increasing awareness of health and environmental issues, people are pursuing healthier, more comfortable, and more environmentally friendly lifestyles. Various odors in the environment, such as ammonia, acid, sulfur, smoke, and formaldehyde, can affect people's health and mood. Industrial environmental pollution, such as paint, spray towers, chemical plants, waste transfer stations, and livestock farms, can cause severe odor damage, harming human health and polluting the environment. Highly effective and safe odor removal products, such as home odor removal products, air fresheners, deodorizers for seniors' rooms, car deodorizers and pet care products, and odor source treatment agents for industrial plants and mines, are attracting widespread attention and demand.
[0003] Odors primarily originate from sulfur-containing molecules (such as sulfur dioxide, hydrogen sulfide, and methyl mercaptan); nitrogen-containing molecules (such as ammonia, trimethylamine, and odor-causing organic amines); oxygen-containing molecules (such as formaldehyde, acetic acid, isovaleric acid, acetaldehyde, and nonenal); and TVOCs, nicotine, and tobacco smoke. The primary cause of underarm odor is excessive secretion and excretion of organic matter by the apocrine sweat glands, which is then broken down by bacteria on the skin (such as Staphylococcus epidermidis). This produces short-chain unsaturated fatty acids and small-molecule ammonia-nitrogen compounds, such as hexanoic acid, octanoic acid, thiols, amines, and indoles, which in turn produce the unpleasant odor.
[0004] Commonly used deodorizers on the market suffer from poor efficacy and safety risks. People are increasingly choosing natural, effective, and safe products, and these products are trending towards being safer, gentler, greener, and more efficient. To address these issues, the market needs to develop a natural, effective, and safe deodorizing product to meet people's needs in both living and industrial environments.
[0005] Therefore, the research and development of such products has good application prospects and is very beneficial and necessary. Summary of the Invention
[0006] The purpose of the present invention is to provide a composition which has significant deodorizing effect and is safe to use.
[0007] The purpose of the present invention is achieved by adopting the following technical solutions:
[0008] The invention discloses a composition with the function of removing odors, which is obtained by uniformly mixing zinc ricinoleate grease, lemon peel oil and glutathione in a mass ratio of 1-15:1-15:1-15.
[0009] In the present invention, the ricinoleate zinc grease is obtained by activating ricinoleate zinc with amino acids, wherein the active zinc content is greater than 5000 ppm.
[0010] In the present invention, the lemon peel oil is extracted from lemon peel, wherein the limonene content is greater than 10%.
[0011] In the preferred technical solution, the mass ratio of zinc ricinoleate, lemon peel oil, and glutathione is 1:1:1.
[0012] In the present invention, zinc ricinoleate grease, lemon peel oil and glutathione are prepared with a solvent (water, ethanol, etc.) into an aqueous solution or a gel.
[0013] In the present invention, the composition is a spray, a gel or an emulsion.
[0014] In the present invention, zinc ricinoleate, lemon peel oil and glutathione are mixed with excipients to prepare a cream.
[0015] Beneficial effects: Zinc ricinoleate is an environmentally friendly, safe and environmentally friendly molecule, lemon peel oil is also a natural volatile oil extract, and glutathione is a small molecule peptide with important physiological activity. The combination of the three significantly improves the deodorization effect. Since the raw materials are derived from natural products, they are relatively safe and have good application prospects. DETAILED DESCRIPTION
[0016] The present invention will be further described below with reference to the embodiments.
[0017] Example 1
[0018] The composition A with deodorizing effect is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 1:1:1.
[0019] The preparation method for ricinoleic acid zinc grease is as follows: 100g of zinc ricinoleate and 1000g of water are added to a reactor, heated to 60°C while stirring and maintained, 100g of arginine is added as an amino acid activation aid, and stirring is continued for 1 hour. Impurities are removed by filtration, the filtrate is collected, and cooled to room temperature to obtain ricinoleic acid zinc grease. Its properties are as follows: a slightly yellow, clear liquid, slightly viscous and greasy, with a characteristic castor oil odor, and soluble in water. The active zinc content in the ricinoleic acid zinc grease was determined by spectrophotometry to be 35190 ppm.
[0020] Lemon peel oil was extracted using supercritical CO₂ extraction. The specific method was as follows: lemon peel was washed, sliced, dried, and then crushed. The oil was extracted using supercritical CO₂ extraction at a temperature of 45°C, a pressure of 25 MPa, an extraction time of 150 minutes, and a CO₂ flow rate of 25 L / h. The resulting lemon peel oil was observed and weighed, and the limonene content (mg / g) was determined by gas chromatography. Results: The lemon peel oil was a light yellow oil with a lemony odor and a limonene content of 532.60 mg / g.
[0021] Glutathione, properties: powder, content: 99.8%, purchased from Zhejiang Yinuo Biotechnology Co., Ltd.
[0022] Preparation of deodorizing spray: To 30 g of deodorizing composition A, add 960 g of deionized water and 10 g of cosolvent hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain 1000 g of deodorizing spray containing 10 g of zinc ricinoleate, 10 g of lemon peel oil, and 10 g of glutathione.
[0023] Example 2
[0024] The composition B having the function of removing odor is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 5:5:1.
[0025] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0026] A cream was prepared using a known and commonly used cream preparation method, using the deodorizing composition B as the active ingredient. 1000 g of the cream contained 55 g of the deodorizing composition B, which included 25 g of zinc ricinoleate, 25 g of lemon peel oil, and 5 g of glutathione.
[0027] Example 3
[0028] The composition C having the function of removing odor is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 1:10:2.
[0029] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0030] According to a known and commonly used gel preparation method, a gel was prepared using the deodorizing composition C as the active ingredient. 1000 g of the gel contained 2 g of zinc ricinoleate, 20 g of lemon peel oil, and 4 g of glutathione.
[0031] Example 4
[0032] The composition D having the function of removing odor is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 10:3:3.
[0033] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0034] Preparation of deodorizing spray: To 32 g of deodorizing composition D, add 958 g of deionized water and 10 g of the cosolvent hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain 1000 g of deodorizing spray containing 20 g of zinc ricinoleate, 6 g of lemon peel oil, and 6 g of glutathione.
[0035] Example 5
[0036] The composition E having the function of removing odor is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 5:2:1.
[0037] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0038] Preparation of deodorizing spray: To 40 g of deodorizing composition E, add 950 g of deionized water and 10 g of cosolvent hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain 1000 g of deodorizing spray containing 25 g of zinc ricinoleate, 10 g of lemon peel oil, and 5 g of glutathione.
[0039] Example 6
[0040] The composition F having the function of removing odor is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 1:1:2.
[0041] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0042] Preparation of deodorizing spray: To 40 g of deodorizing composition F, add 950 g of deionized water and 10 g of the cosolvent hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain 1000 g of deodorizing spray containing 10 g of zinc ricinoleate, 10 g of lemon peel oil, and 20 g of glutathione.
[0043] Example 7
[0044] The composition G having the function of removing odor is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 5:1:1.
[0045] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0046] Preparation of deodorizing spray: To 35 g of deodorizing composition G, add 955 g of deionized water and 10 g of cosolvent hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain 1000 g of deodorizing spray containing 25 g of zinc ricinoleate, 5 g of lemon peel oil, and 5 g of glutathione.
[0047] Example 8
[0048] The composition H having the function of removing odor is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 10:1:1.
[0049] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0050] Preparation of deodorizing spray: To 36 g of deodorizing composition H, add 954 g of deionized water and 10 g of the cosolvent hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain 1000 g of deodorizing spray containing 30 g of zinc ricinoleate, 3 g of lemon peel oil, and 3 g of glutathione.
[0051] Example 9
[0052] The composition I with deodorizing function is obtained by uniformly mixing ricinoleic acid zinc grease, lemon peel oil and glutathione in a mass ratio of 1:5:5.
[0053] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0054] Preparation of deodorizing spray: To 33 g of deodorizing composition I, add 957 g of deionized water and 10 g of the cosolvent hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir until uniform. This yields 1000 g of deodorizing spray containing 3 g of zinc ricinoleate, 15 g of lemon peel oil, and 15 g of glutathione.
[0055] Example 10
[0056] The composition J having the function of removing odor is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 1:5:10.
[0057] The preparation method or sources of ricinoleic acid zinc grease, lemon peel oil and glutathione are the same as those in Example 1.
[0058] Preparation of deodorizing spray: To 32 g of deodorizing composition J, add 958 g of deionized water and 10 g of cosolvent hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain 1000 g of deodorizing spray containing 2 g of zinc ricinoleate, 10 g of lemon peel oil, and 20 g of glutathione.
[0059] Example 11 Deodorization efficacy test and safety evaluation experiment
[0060] The deodorizing spray prepared in Example 1 was subjected to relevant deodorizing efficacy tests and safety evaluation experiments.
[0061] 1. The deodorizing effect of the deodorizing spray prepared in Example 1 on odor sources such as trimethylamine, garlic oil, isovaleric acid, and cigarette smoke
[0062] The deodorizing effect of the deodorizing spray prepared in Example 1 on odor sources such as trimethylamine, garlic oil, isovaleric acid, and cigarette smoke was investigated. The specific method is as follows:
[0063] (1) Preparation of control drug
[0064] Control spray 1: Take 10 g of ricinoleic acid zinc grease, add 980 g of deionized water, and 10 g of hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain control spray 1.
[0065] Control spray 2: Take 10 g of lemon peel oil, add 980 g of deionized water, and 10 g of hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain control spray 2.
[0066] Control spray 3: Take 10 g of glutathione, add 980 g of deionized water, and 10 g of hydrogenated castor oil PEG40 (CO40, BASF, Germany), and stir evenly to obtain control spray 3.
[0067] Control spray 4: 10 g of zinc ricinoleate grease and 10 g of lemon peel oil were mixed, 970 g of deionized water and 10 g of hydrogenated castor oil PEG40 (CO40, BASF, Germany) were added, and stirred evenly to obtain control spray 4.
[0068] Control spray 5: 10 g of zinc ricinoleate and 10 g of glutathione were mixed, 970 g of deionized water and 10 g of hydrogenated castor oil PEG40 (CO40, BASF, Germany) were added, and stirred evenly to obtain control spray 5.
[0069] Control spray 6: 10 g of lemon peel oil and 10 g of glutathione were mixed, 970 g of deionized water and 10 g of hydrogenated castor oil PEG40 (CO40, BASF, Germany) were added, and stirred evenly to obtain control spray 6.
[0070] (2) Preparation of odor source
[0071] Prepare 1% mass concentrations of isovaleric acid, trimethylamine, and garlic oil solutions in deionized water. Add 50 μL of each solution to each cotton pad (5 cm × 5 cm × 2 mm) to serve as a volatile odor source. For the cigarette odor test strips, lay a soaked cotton pad (5 cm × 5 cm × 2 mm) flat on a stainless steel rack. Place the rack in a partially sealed container (30 cm × 30 cm × 20 cm). Place a cigarette under the rack, light it, and secure it. Once the cigarette has burned out, remove the test strips and use them as cigarette strips.
[0072] (3) Deodorization experimental method
[0073] The deodorizing spray prepared in Example 1 and control sprays 1-6 were sprayed on the odorous cotton pads obtained in step (2), respectively, with 1 ml sprayed on the front and back of each odorous cotton pad. At the same time, an odorous cotton pad not sprayed with any substance was set as a blank, and deionized water was used instead of the deodorizing spray as a negative control group.
[0074] (4) Deodorization effect evaluation - subjective evaluation method
[0075] Ten panelists evaluated the deodorizing effect of the spray one hour after application. The subjects' subjective perception of odor reduction after application was compared to an unapplied cotton pad. A 100% odor reduction rate indicated complete odor removal, a 0% odor reduction rate, and a partial odor reduction rate of 0 < 100% odor reduction. See Table 1 for details.
[0076] Table 1 Score criteria for sensory evaluation of odor
[0077] Odor removal rate 100％ 75％ 50％ 25％ 0 Subjects' subjective feelings Completely remove odor Odor removal 1 / 4 Odor removal 1 / 2 Odor removal 3 / 4 The odor is not removed at all
[0078] (4) Experimental results and analysis
[0079] The results (Table 2) show that the deodorizing spray prepared in Example 1 has a good effect of removing odors of trimethylamine, isovaleric acid, garlic oil, and cigarette smoke.
[0080] Table 2 Deodorizing effect of the deodorizing spray prepared in Example 1 (odor removal rate / %)
[0081] Spray name Trimethylamine Isovalerate Garlic oil Smoke Deionized water (negative control group) 9％ 8％ 9％ 11％ Control spray 2 35％ 39％ 29％ 37％ Control spray 3 19％ 18％ 16％ 15％ Control spray 1 46％ 52％ 52％ 47％ Control spray 6 41％ 40％ 34％ 40％ Control spray 5 46％ 53％ 56％ 48％ Control spray 4 55％ 59％ 70％ 69％ Deodorant spray prepared in Example 1 96％ 95％ 90％ 92％
[0082] 2. Quantitative Analysis of the Deodorizing Effect of the Deodorizing Spray Prepared in Example 1 on the Odor Sources of Trimethylamine and Isovaleric Acid (1) Experimental Method
[0083] Isovaleric acid and trimethylamine were prepared into 0.01 g / mL aqueous solutions. 2.5 μL of isovaleric acid or trimethylamine aqueous solution was added to a 2 mL Dulbecco's tube, which was then placed in a 20 mL headspace vial. The deodorizing spray prepared in Example 1 and control sprays 1-6 were then added to the headspace vials to examine the odor removal effects of each spray. The headspace vials were heated in a 40°C water bath for 20 minutes, then left at 25°C overnight before measuring the odorous gas content using solid phase microextraction-gas chromatography-mass spectrometry (GC-MS). A blank control was also performed, with isovaleric acid and trimethylamine solutions added but no deodorant added.
[0084] SPME conditions: After equilibration overnight at 25°C, the headspace vial was placed in a 45°C water bath for 20 minutes. Extraction was then performed using a 50 / 30 μm DVB / CAR / PDMS tip for 15 minutes, followed by inlet desorption for 6 minutes. The tip was conditioned at 270°C for 10 minutes.
[0085] Gas chromatography conditions: chromatographic column: DB-5MS, 30m×0.25mm×0.25μm, carrier gas: high-purity helium, flow rate: 1.0mL / min, inlet temperature: 220℃, split ratio: 10:1, temperature program (for detection of trimethylamine): hold at 40℃ for 3min, increase to 120℃ at a rate of 10℃ / min, hold at 120℃ for 2min, then increase to 270℃ at a rate of 5℃ / min, hold at 270℃ for 2min; temperature program (for detection of isovaleric acid): hold at 40℃ for 3min, then increase to 100℃ at a rate of 10℃ / min, hold at 100℃ for 2min, then increase to 270℃ at a rate of 5℃ / min, hold at 270℃ for 2min.
[0086] Mass spectrometry conditions: Ion source: electron impact ionization source (EI source), temperature: 220°C; ionization energy: 70 eV; quadrupole temperature: 150°C; transfer line temperature: 230°C; solvent delay: 0 min; scan mode: selected ion scanning (SIM); scan ion selection: ammonia m / z 16, 17, 18, trimethylamine m / z 30, 42, 58, 59, isovaleric acid m / z 41, 43, 60, 87; scan range: m / z 10-110. The deodorization effect was calculated using the following formula:
[0087]
[0088] Where: S1 is the peak area of odorous gas before deodorization; S2 is the peak area of odorous gas after deodorization.
[0089] (5) Experimental results and analysis
[0090] The results show (see Table 3) that the deodorizing spray prepared in Example 1 has a good odor removal effect on both trimethylamine and isovaleric acid.
[0091] Table 3 Deodorizing effect of the deodorizing spray prepared in Example 1 (odor gas removal rate / %)
[0092] Spray name Trimethylamine Isovalerate Blank control 0 0 Control spray 2 25.96％ 20.37％ Control spray 3 21.97％ 25.79％ Control spray 1 40.57％ 41.21％ Control spray 6 38.46％ 42.05％ Control spray 5 54.49％ 60.41％ Control spray 4 61.60％ 56.84％ Deodorant spray prepared in Example 1 98.97％ 96.01％
[0093] 3. Deodorizing effect of the deodorizing spray prepared in Example 1 on underarm odor
[0094] (1) Experimental method: The following method was used to test the deodorizing effects of the deodorizing spray prepared in Example 1 and control sprays 1-6 on underarm odor: a patient with underarm odor was randomly selected, and the axilla of the patient was wiped with sterile facial tissue to obtain a sample. The sample was immediately placed in 25 ml of ammonia-free water, and the ammonia nitrogen content (which can reflect the amount of protein decomposition products in underarm secretions) and the free fatty acid content of the solution were measured, and recorded as the initial ammonia nitrogen content and the initial free fatty acid content. Every 24 hours (the time interval between two adjacent sprays), 1 ml of the deodorizing spray prepared in Example 1, control sprays 1-6, and deionized water were sprayed on the underarm, and 6 hours after each spray or deionized water was sprayed, the same method was used to obtain a sample, and the sample was immediately placed in 25 ml of ammonia-free water, and the ammonia nitrogen content (which can reflect the amount of protein decomposition products in underarm secretions) and the free fatty acid content of the solution were measured. The reduction in ammonia nitrogen and free fatty acids in the patients' axillary secretions after treatment with each deodorizing spray was calculated relative to the initial ammonia nitrogen content and the initial free fatty acid content.
[0095] (2) Experimental results and analysis: The results show (see Table 4) that the deodorizing spray prepared in Example 1 can significantly reduce the content of ammonia nitrogen compounds, that is, it can significantly inhibit the decomposition of underarm sweat protein and reduce the production of ammonia nitrogen compound odor substances; the deodorizing spray prepared in Example 1 can also significantly reduce the content of free fatty acids, thereby reducing the production of odor-causing substances.
[0096] Table 4 Deodorizing effect of the deodorizing spray prepared in Example 1 on underarm odor
[0097]
[0098]
[0099] 3. Safety evaluation experiment
[0100] (1) Acute inhalation toxicity test
[0101] Experimental method: The acute inhalation toxicity test was conducted using the application limit test method. 20 ICR mice, half male and half female, SPF grade, weighing 18-22 g. In a static poison control cabinet, the deodorizing spray prepared in Example 1 was tested at a concentration of 10,000 mg / m 3 The experiment was conducted under the following conditions: the 20 mice were exposed to the deodorizing spray prepared in Example 1 for 2 hours in a static exposure mode. The toxicity of the mice was observed 14 days after the end of the exposure. At the end of the experiment, the pathological changes of the tissues and organs were observed with the naked eye. The acute inhalation median lethal concentration (LC50) of the test sample in mice was determined based on the death of the animals. 50 ) and determine the toxicity classification of the test sample in accordance with the evaluation provisions of the "Acute Inhalation Toxicity Test" in the "Technical Specifications for Disinfection" (2002 edition).
[0102] Experimental results: During and after the exposure, no abnormal signs related to the exposure were observed in the experimental animals. No deaths occurred in either male or female animals during the observation period. The test sample (the deodorizing spray prepared in Example 1) had an acute inhalation median lethal concentration (LC50) greater than 10,000 mg / m2 for both female and male ICR mice. 3 Weight, toxicity level was determined to be practically non-toxic.
[0103] (2) Acute oral toxicity test
[0104] Experimental method: The acute oral toxicity test was conducted using a single maximum test method. Twenty ICR mice, half male and half female, SPF grade, weighing 18-22 g, were administered with the deodorizing spray prepared in Example 1 at a dose of 5000 mg / kg. Before the test, the animals were fasted overnight, and drinking water was not restricted. The deodorizing spray prepared in Example 1 was administered to the test animals once by oral gavage, with a sample volume of 0.2 mL / 10 g·bw. The animals were closely observed for 4 hours after the sample was administered, and the toxicity of the mice was observed 14 days after the sample was administered. At the end of the test, gross dissection was performed, and the pathological changes of the tissues and organs were observed with the naked eye. According to the death of the animals, the acute oral median lethal dose (LD50) of the test sample (deodorizing spray prepared in Example 1) in mice was determined. 50 ) and determine the toxicity classification of the test sample in accordance with the evaluation provisions of 2.3.1.6 in the Technical Specifications for Disinfection (2002 edition).
[0105] Experimental results: After the sample was administered, no abnormal physical signs related to the sample were observed in the experimental animals. During the observation period, no deaths occurred in either male or female animals. At the end of the experimental observation, the test animals were subjected to gross anatomical examination and no abnormal changes were found. The test sample (the deodorizing spray prepared in Example 1) had an acute oral median lethal dose (LD50) of 1.5 mg / dL in female and male ICR mice. 50 ) were greater than 5000 mg / kg body weight, and the toxicity level was judged to be practically non-toxic.
[0106] (3) Local skin irritation test
[0107] Experimental method: 8 adult rabbits were collected, half male and half female, and each animal was housed in a separate cage. They were first raised in the laboratory for 3-4 days. Then, the hair on both sides of the rabbit spine was shaved with an electric shaver, with an area of 5×10 cm on each side. 2 Carefully check the hair removal area for redness, swelling, and damage. If any, discard the area and do not proceed with the test. A multiple-dose test method was used. Apply the deodorizing spray prepared in Example 1 to the hair removal area, 2 ml each time, twice a day for 7 consecutive days. Wash off the smear with warm water 24 hours after the last application. Observe local skin reactions such as erythema, edema, desquamation, scabs, etc., and whether there are bleeding spots, rough or thin skin, etc., and record the time of occurrence and disappearance.
[0108] Experimental results: After continuous application of the deodorizing spray prepared in Example 1 for 7 days, none of the rabbits showed obvious skin irritation or allergic reaction, indicating that the deodorizing spray prepared in Example 1 is safe, has no adverse reactions, is non-toxic, and is non-irritating.
Claims
1. A composition having a deodorizing effect, characterized in that: The invention is obtained by uniformly mixing zinc ricinoleate, lemon peel oil and glutathione in a mass ratio of 1-15:1-15:1-15.
2. The composition according to claim 1, characterized in that The ricinoleate zinc grease is obtained by activating ricinoleate zinc with amino acids, wherein the active zinc content is greater than 5000 ppm.
3. The composition according to claim 2, characterized in that The lemon peel oil is extracted from lemon peel, wherein the limonene content is greater than 10%.
4. The composition according to claim 1, 2 or 3, characterized in that: The mass ratio of zinc ricinoleate, lemon peel oil and glutathione is 1:1:
1.
5. The composition according to claim 4, characterized in that: Zinc ricinoleate, lemon peel oil and glutathione are prepared into an aqueous solution or gel with a solvent (water, ethanol, etc.).
6. The composition according to claim 5, characterized in that The composition is in the form of a spray, a gel or an emulsion.
7. The composition according to claim 4, characterized in that Zinc ricinoleate, lemon peel oil and glutathione are mixed with excipients to form a cream.