Fermentation preparation method and synthesis method of microcrystalline cellulose

Abstract

The invention provides a fermentation preparation method and a synthesis method of microcrystalline cellulose, and relates to the field of microcrystalline cellulose. The synthetic method of microcrystalline cellulose comprises the following steps: S1, sequentially injecting water, microcrystalline cellulose and sodium benzoate into a stirring device according to a required proportion; s2, stirring the mixed liquid for a proper time; s3, heating the stirring space to a proper range; s4, the stirred liquid is subjected to vacuum defoaming treatment, the proportion of the microcrystalline cellulose in the S1 is 0.8%-1.2%, the proportion of the sodium benzoate in the S1 is 0.3%-0.7%, and the mixing time in the S2 is longer than 30 minutes. The product has excellent suspension performance and can stably suspend various solid components such as petals, mica and traditional Chinese medicine particles, uniform distribution of diversified components is ensured, the smoothness and smearing experience in the using process are improved through the nano structure of the product, foam forming and stability are not affected, operation is convenient and fast, dissolving or activation in advance is not needed, and the product has good application prospects. The use is more convenient.

Description

Technical Field

[0001] The present invention relates to the field of microcrystalline cellulose, in particular to a fermentation preparation method and a synthesis method of microcrystalline cellulose. Background Art

[0002] Microcrystalline cellulose is a high-purity, highly crystalline cellulose material extracted from plant cellulose and obtained through acid hydrolysis. It is commonly used in pharmaceuticals, food, cosmetics and other fields as a filler, thickener, emulsifier and stabilizer. Due to its excellent stability and non-toxicity, microcrystalline cellulose is widely used in pharmaceutical preparations to help improve the solubility and bioavailability of drugs. It is also often used in food to increase texture and improve taste.

[0003] However, the synthesis process of traditional microcrystalline cellulose usually requires multi-step reactions, long processing time and high temperature and high pressure conditions, resulting in cumbersome processes, low efficiency, high production costs, and affecting the stability of the foam structure. These problems limit its application effect and sustainability in certain fields.

[0004] Therefore, those skilled in the art provide a fermentation preparation method and a synthesis method of microcrystalline cellulose to solve the problems raised in the above background technology. Summary of the Invention

[0005] (1) Technical problems solved

[0006] In view of the shortcomings of the existing technology, the present invention provides a fermentation preparation method and a synthesis method of microcrystalline cellulose, which solves the problems of complicated process and low efficiency.

[0007] (2) Technical solution

[0008] To achieve the above objectives, the present invention is implemented through the following technical solutions:

[0009] A method for synthesizing microcrystalline cellulose comprises the following steps:

[0010] S1. According to the desired ratio, water, microcrystalline cellulose and sodium benzoate are injected into a stirring device;

[0011] S2. Stir the mixed liquid for a suitable time;

[0012] S3. Heat the stirring space to a suitable range;

[0013] S4. Perform vacuum defoaming treatment on the stirred liquid.

[0014] Through the above technical solution, the product uses natural organic materials, is safe and gentle, conforms to the current carbon neutrality trend, and has good environmental properties. At the same time, it has super water-holding capacity and long-lasting moisturizing effect, which helps protect the skin and double care.

[0015] Furthermore, the water content in the S1 is 98.1% to 98.9%.

[0016] Furthermore, the proportion of microcrystalline cellulose in S1 is 0.8% to 1.2%;

[0017] Through the above technical solution, the addition of microcrystalline cellulose can enhance its dispersion effect by increasing the stirring rate.

[0018] Furthermore, the proportion of sodium benzoate in S1 is 0.3% to 0.7%;

[0019] Through the above technical solution, sodium benzoate has a certain antiseptic effect, which helps to extend the shelf life of the product.

[0020] Furthermore, the mixing time in S2 is greater than 30 minutes;

[0021] Through the above technical solution, the consistency of the materials after mixing is suitable and they can be completely dissolved and mixed together.

[0022] Furthermore, the heating temperature in S3 is controlled within the range of 80-100°C;

[0023] Through the above technical solution, the structure of cellulose can be avoided from being destroyed within a suitable temperature, the efficiency of mixing various materials can be improved, and the suitable temperature can better dissolve other raw materials.

[0024] (3) Beneficial effects

[0025] The present invention provides a fermentation preparation method and a synthesis method for microcrystalline cellulose. It has the following beneficial effects:

[0026] 1. The present invention provides a fermentation preparation method and a synthesis method of microcrystalline cellulose. The product uses natural organic materials, is safe and mild, conforms to the current carbon neutrality trend, has good environmental properties, and at the same time, has super water-holding capacity and long-term moisturizing effect, which helps protect the skin and doubles the care.

[0027] 2. The present invention provides a fermentation preparation method and a synthesis method of microcrystalline cellulose. The product has excellent suspension properties and can stably suspend a variety of solid ingredients such as flower petals, mica, and traditional Chinese medicine particles, ensuring uniform distribution of diverse ingredients. Its nanostructure enhances the smoothness and application experience during use without affecting the formation and stability of foam. It is easy to operate and does not require pre-dissolution or activation, making it more convenient to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 Schematic diagram of the microcrystalline cellulose composition of the present invention;

[0029] Figure 2 It is a schematic diagram of the process of the present invention. DETAILED DESCRIPTION

[0030] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0031] Example 1:

[0032] like Figure 1-2 As shown, the embodiment of the present invention provides a method for synthesizing microcrystalline cellulose, comprising the following steps:

[0033] S1. According to the desired ratio, water, microcrystalline cellulose and sodium benzoate are injected into a stirring device;

[0034] S2. Stir the mixed liquid for a suitable time;

[0035] S3. Heat the stirring space to a suitable range;

[0036] S4. Perform vacuum defoaming treatment on the stirred liquid.

[0037] This product has excellent suspension properties and can stably suspend a variety of solid ingredients such as flower petals, mica, Chinese medicine particles, etc., ensuring that the diverse ingredients are evenly distributed. Its nanostructure enhances the smoothness and application experience during use without affecting the formation and stability of foam. It is easy to operate and does not require pre-dissolution or activation, making it more convenient to use.

[0038] The proportion of water in S1 is 98.1% to 98.9%, the proportion of microcrystalline cellulose in S1 is 0.8% to 1.2%, and the addition of microcrystalline cellulose can enhance its dispersion effect by increasing the stirring rate. The proportion of sodium benzoate in S1 is 0.3% to 0.7%. Sodium benzoate has a certain preservative effect and helps to extend the shelf life of the product. The mixing time in S2 is greater than 30 minutes, so that the consistency of the mixed materials is suitable and can be completely dissolved and mixed together. The heating temperature in S3 is controlled in the range of 80 to 100°C. Within the suitable temperature, the structure of cellulose can be avoided from being destroyed, the efficiency of mixing of various materials can be improved, and the suitable temperature can better dissolve other raw materials.

[0039] Example 2:

[0040] How to use:

[0041] 1. It has little effect on the viscosity of the system. It needs to have a consistency when added. During production, it is necessary to ensure sufficient stirring / low-speed homogenization for 30 minutes until it is completely dissolved;

[0042] 2. The most suitable suspension base formula for the product is recommended to be added at a dosage of more than 15%. The higher the surfactant content, the better the suspension power, which is conducive to forming a stable 3D suspension structure.

[0043] 3. 2.5% can suspend mica powder, etc.

[0044] 4. 2.5-5% can effectively suspend petals (real flowers);

[0045] 5. 2.5-6% can be used to suspend various particles (such as ginger, Chinese medicine, etc.);

[0046] 6. The product is compatible with anionic systems, but more testing is needed for cationic systems.

[0047] Among them, it is worth noting that:

[0048] 1. The long-term antifreeze (-18°C) surface of this product is not stable enough at present. Customers who need to test the antifreeze conditions can test it by themselves;

[0049] 2. The higher the amount of AES added, the higher the surfactant content, the better the suspension power and the better the transparency;

[0050] 3. Ensure that the added product system has appropriate sufficient viscosity;

[0051] 4. The formula cannot achieve complete transparency. There will be slightly acceptable blue light and fogging. Adding some pigments can enhance the transparent appearance of the product.

[0052] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A method for synthesizing microcrystalline cellulose, characterized in that: The following steps are involved: S1. According to the desired ratio, water, microcrystalline cellulose and sodium benzoate are injected into a stirring device; S2. Stir the mixed liquid for a suitable time; S3. Heat the stirring space to a suitable range; S4. Perform vacuum defoaming treatment on the stirred liquid.

2. The method for synthesizing microcrystalline cellulose according to claim 1, wherein: The water content in the S1 is 98.1% to 98.9%.

3. The method for synthesizing microcrystalline cellulose according to claim 1, wherein: The content of microcrystalline cellulose in the S1 is 0.8% to 1.2%.

4. The method for synthesizing microcrystalline cellulose according to claim 1, wherein: The proportion of sodium benzoate in S1 is 0.3% to 0.7%.

5. The method for synthesizing microcrystalline cellulose according to claim 1, wherein: The mixing time in S2 is greater than 30 minutes.

6. The method for synthesizing microcrystalline cellulose according to claim 1, wherein: The heating temperature in S3 is controlled within the range of 80-100°C.

7. The fermentation preparation method of the microcrystalline cellulose according to claim 1-6, characterized in that: The following steps are involved: 1) Seed culture: preparing microbial seeds required for fermentation production; 2) Fermentation production: In the fermenter, microorganisms convert the raw sugar into microcrystalline cellulose; 3) Solid-liquid separation: separating the microcrystalline cellulose solids from the fermentation material; 4) Microcrystalline cellulose cake: The separated solid is the microcrystalline cellulose cake, which is washed to remove impurities; 5) Activation and compounding: obtaining an easily dispersible microcrystalline cellulose solution; 6) Finished product packaging: Packed into different specifications and put into storage after passing inspection.

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