Radioactive particle placement net bag for vertebroplasty and use method of radioactive particle placement net bag
Through the design of the double-layer mesh bag structure, the precise positioning and firm fixation of radioactive particles are achieved, which solves the problem of particle implantation during vertebroplasty and improves the safety and effectiveness of treatment.
Patent Information
- Application Number
- CN202510921313.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-04
- Publication Date
- 2025-09-09
AI Technical Summary
In existing technologies, it is difficult to accurately position and firmly fix radioactive particles within the vertebral body, resulting in high surgical risks, particle displacement or floating, and affecting the treatment effect.
A double-layer mesh bag structure is adopted, with the inner and outer mesh bodies spaced and connected to form a modular structure. The inner mesh body serves as the bone cement injection channel, and the outer mesh body serves as the radioactive particle storage space. The precise positioning and fixation of the particles are achieved through the injection connection mechanism and the placement mechanism.
It improves the accuracy and safety of radioactive seed implantation, reduces damage to surrounding normal tissues, and ensures the effectiveness and safety of radiotherapy.
Smart Images
Figure CN120605459A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of medical devices, and in particular to a radioactive particle placement mesh bag for vertebroplasty and a method for using the mesh bag. Background Art
[0002] The treatment of vertebral and paravertebral tumors has always been a significant clinical challenge. Because of their proximity to vital neurovascular structures, surgical resection of these tumors is invasive and risky, while external beam radiotherapy is limited by the dose tolerance of sensitive surrounding organs, resulting in suboptimal efficacy. Radioactive seed interstitial brachytherapy, leveraging its unique advantages of delivering high doses to the lesion and rapidly decaying doses to the surrounding tissues, effectively kills the tumor while significantly sparing surrounding normal tissues.
[0003] Combining radioactive seed implantation with vertebroplasty is theoretically the optimal approach for treating vertebral tumors. However, the core bottleneck of this combined technique lies in the precise positioning and secure fixation of the radioactive seeds within the vertebral body during surgery. Existing seed implantation devices widely used in clinical practice are primarily designed for soft tissue. These devices lack bone compatibility, making precise manipulation difficult within hard or damaged bone. Furthermore, the fixation mechanism fails, and the seeds are prone to displacement, sedimentation, or floating in uncured bone cement.
[0004] Therefore, there is an urgent need for a specialized device designed for precise particle positioning and reliable fixation during vertebroplasty. Summary of the Invention
[0005] In order to solve the problems existing in the background technology, the present invention proposes a mesh bag for implanting radioactive particles for vertebroplasty and a method of using the mesh bag, which is adaptable to clinical needs, can be flexibly adjusted and precisely controlled, and realizes the effective combination of radioactive particle implantation and vertebroplasty, thereby improving the safety and effectiveness of treatment.
[0006] To achieve the above object, the present invention adopts the following scheme: The radioactive particles are placed in a mesh bag for vertebroplasty, comprising a double-layer mesh bag, wherein the double-layer mesh bag comprises an inner mesh body and an outer mesh body which are interconnected. The inner mesh body forms a first cavity, and the inner mesh body and the outer mesh body are spaced and joined to form a plurality of second cavities arranged circumferentially. One end of the first cavity and the second cavity on the same side is closed by an end cap, and the other end is used to inject bone cement into the first cavity through an injection connection mechanism. Radioactive particles are placed in the second cavity through an insertion mechanism.
[0007] Optionally, the end head is fixed in the first cavity, the end head axially extends out of the first cavity at one end and circumferentially fixes the edges of the inner mesh body and the outer mesh body, and a baffle is provided at the extended end of the end head, which is used to restrict the inner mesh body and the outer mesh body to the end head.
[0008] Optionally, the injection connection mechanism includes an inner injection tube and an outer injection tube, the inner injection tube is sleeved inside the inner mesh body and connected to the first cavity, and the outer injection tube is sleeved on the outside of the outer mesh body; the end of the end close to the injection connection mechanism is connected to a core needle, and the end of the core needle away from the end is passed through the first cavity and out of the inner injection tube.
[0009] Optionally, the edges of the inner mesh body and the outer mesh body at one end of the injection connection mechanism are bonded to each other and clamped between the inner injection tube and the outer injection tube.
[0010] Optionally, the insertion mechanism includes a sleeve and a push rod, the sleeve is a tubular structure with openings at both ends, the sleeve is movably arranged in the second cavity, and one end extends out of the double-layer mesh bag, and the push rod is used to push the radioactive particles into the sleeve.
[0011] Optionally, the radioactive particles are arranged axially in a single row within the sleeve, and spacers are provided between the radioactive particles.
[0012] Optionally, each second cavity is provided with a mounting hole at one end of the end head, and the sleeve is movably inserted into the mounting hole; the open end of the sleeve located outside the double-layer mesh bag is a trumpet-shaped expansion structure.
[0013] The method for using a mesh bag for vertebroplasty with radioactive particles includes the following steps: Step 1: Select the mesh bag model according to clinical needs; Step 2: Use the insertion mechanism to load the second cavity of the double-layer mesh bag with the number of radioactive particles that meet the treatment plan. After loading is completed, remove the insertion mechanism. Step 3: Perform standard vertebroplasty procedures, establish a bone puncture working channel, and insert a mesh bag loaded with radioactive particles into the target area of the vertebral body through the working channel, with the mesh bag fully extended out of the vertebroplasty working cannula. Step 4: Connect a dedicated syringe and slowly inject bone cement into the first cavity of the double-layer mesh bag through the injection connection mechanism. The double-layer mesh bag gradually expands as the bone cement is injected, and a small amount of bone cement diffuses through the mesh of the inner mesh to the outer mesh, fixing the radioactive particles in the predetermined position. Step 5, release the fixed connection of the injection connection mechanism to the double-layer mesh bag and remove the injection connection mechanism; Step 6: The radioactive particles in the second cavity of the double-layer mesh bag adhere closely to the lesion area, and targeted radiotherapy begins immediately; Step 7: Local bandage, and the operation is completed.
[0014] The beneficial effects of the present invention are as follows: first, there is a gap connection between the inner mesh body and the outer mesh body, forming a mesh bag with a modular structure, which is conducive to adapting to different vertebral morphologies. Mesh bags of different forms can be made according to clinical needs, which is convenient for flexible adjustment of the distribution of radioactive particles according to the size and location of the lesion, thereby improving the accuracy of radiotherapy, reducing damage to surrounding normal tissues, and realizing individualized treatment.
[0015] Moreover, the first cavity formed by the inner mesh body serves as a channel for injecting bone cement; the second cavity formed between the inner mesh body and the outer mesh body serves as a storage space for radioactive particles, thereby isolating bone cement from radioactive particles. Only a small amount of bone cement diffuses through the mesh holes of the inner mesh body to the outer mesh body, thus avoiding the displacement of radioactive particles, ensuring that the radiation dose accurately acts on the diseased tissue, and improving the safety and effectiveness of the treatment.
[0016] Furthermore, the combination of the cannula and push rod ensures precise control of the number and distribution of radioactive particles within each double-layer mesh bag, consistent with the treatment plan. The clamping connection between the injection tube and the double-layer mesh bag allows for quick disassembly, minimizing tissue damage. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 A flow chart of a method for using a mesh bag according to the present invention; Figure 2 Schematic diagram of the cross-sectional structure of the double-layer mesh bag of the present invention; Figure 3 This is a schematic diagram of the cross-sectional structure of the mesh bag of the present invention; Figure 4 This is a schematic diagram of the working state of the present invention when pushing radioactive particles in a double-layer mesh bag; Figure 5 This is a schematic diagram of the cross-sectional structure of the double-layer mesh bag after the cannula is removed in an embodiment of the present invention; Figure 6 This is a schematic diagram of the cross-sectional structure of the double-layer mesh bag after bone cement is injected into the present invention.
[0018] Numbers in the figure: 1. Double-layer mesh bag; 101. Inner mesh body; 102. Outer mesh body; 103. First cavity; 104. Second cavity; 105. End; 106. Baffle; 2. Core needle; 3. Inner injection tube; 4. Outer injection tube; 5. Sleeve; 6. Radioactive particles; 7. Spacer block; 8. Mounting hole; 9. Push rod; 10. Bone cement. DETAILED DESCRIPTION
[0019] In order to make the present invention clearer and more understandable, the present invention is described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the embodiment given is only one implementation method and does not represent all embodiments.
[0020] Example 1 Combine Figure 2-Figure 6 This embodiment provides a mesh bag for implanting radioactive particles for vertebroplasty, including a double-layer mesh bag 1, wherein the double-layer mesh bag 1 includes an inner mesh body 101 and an outer mesh body 102 which are interconnected. The inner mesh body 101 forms a first cavity 103, and the inner mesh body 101 and the outer mesh body 102 are spaced and joined to form a plurality of second cavities 104 arranged circumferentially; one end of the first cavity 103 and the second cavity 104 on the same side is closed by an end cap 105, and the other end is used to inject bone cement 10 into the first cavity 103 through an injection connection mechanism; radioactive particles 6 are implanted in the second cavity 104 through an implantation mechanism.
[0021] The inner mesh body 101 and the outer mesh body 102 of the double-layer mesh bag 1 are spaced apart to form a plurality of circumferentially distributed bag-like cavities, namely the second cavity 104. In addition, the first cavity 103 forms a mesh bag with a modular structure, which is conducive to adapting to different vertebral morphologies. According to clinical needs, multiple second cavities 104 can be evenly arranged, spaced apart, or arranged on one side to make mesh bags of different forms, so as to flexibly adjust the distribution of radioactive particles 6 according to the size and location of the lesion, improve the accuracy of radiotherapy, reduce damage to surrounding normal tissues, and realize individualized treatment. The radial dimension of the cross section of each second cavity 104 is ≥1.2mm. The spaced joints here can be bonded or woven, so the second cavity is a plurality of circumferentially distributed bag-like cavities. The first cavity 103 formed by the inner mesh body 101 serves as a channel for injecting bone cement 10 into the mesh bag; the second cavity 104 formed between the inner mesh body 101 and the outer mesh body 102 serves as a storage space for the radioactive particles 6, thereby isolating the bone cement 10 from the radioactive particles 6. Only a small amount of bone cement 10 diffuses through the mesh holes of the inner mesh body 101 to the outer mesh body 102, thereby avoiding the displacement of the radioactive particles 6.
[0022] Therefore, the mesh bag is adaptable to clinical needs, can be flexibly adjusted, and precisely manipulated, achieving an effective combination of radioactive particle placement and vertebroplasty, thereby improving the safety and effectiveness of treatment.
[0023] Specifically, the end cap 105 is fixed within the first cavity 103. One axial end of the end cap 105 extends out of the first cavity 103 and circumferentially secures the edges of the inner mesh 101 and outer mesh 102. A baffle 106 is provided at the extended end of the end cap 105, which is used to confine the inner mesh 101 and outer mesh 102 to the end cap 105. The end cap 105 not only seals the first cavity 103 and the second cavity 104, but also, because it can be clearly seen under X-ray fluoroscopy, it can serve as a reference point for the front end position of the mesh bag during vertebroplasty.
[0024] Specifically, the injection connection mechanism includes an inner injection tube 3 and an outer injection tube 4. The inner injection tube 3 is sleeved inside the inner mesh body 101 and communicates with the first cavity 103, and the outer injection tube 4 is sleeved on the outside of the outer mesh body 102; the end of the terminal 105 close to the injection connection mechanism is connected to a core needle 2, and the end of the core needle 2 away from the terminal 105 is passed through the first cavity 103 and out of the inner injection tube 3. The core needle 2 is convenient for supporting the mesh bag to be implanted into the vertebral body. As a preferred embodiment, the end portion of the terminal 105 connected to the core needle 2 is provided with an internal thread, and the core needle 2 is provided with an external thread that matches the internal thread for easy disassembly. The edges of the inner mesh body 101 and the outer mesh body 102 at one end of the injection connection mechanism are bonded to each other and clamped between the inner injection tube 3 and the outer injection tube 4. This clamping and fixation facilitates rapid disassembly during surgery and can reduce tissue damage. The length of the inner injection tube 3 extending into the double-layer mesh bag 1 is greater than that of the outer injection tube 4. In this embodiment, the inner injection tube 3 extends to the initial point where the inner mesh body 101 and the outer mesh body 102 are bonded and connected, that is, the first cavity 103.
[0025] Specifically, the insertion mechanism includes a sleeve 5 and a push rod 9. The sleeve 5 is a tubular structure with two ends open. The sleeve 5 is movably inserted into the second cavity 104, and one end extends out of the double-layer mesh bag 1. The push rod 9 is used to push the radioactive particles 6 into the sleeve 5. The radioactive particles 6 are arranged axially in a single row in the sleeve 5, and spacer blocks 7 are provided between the radioactive particles 6. It should be noted that the number of radioactive particles 6 to be loaded is determined according to the treatment needs. If the treatment requires a gap between the radioactive particles 6, artificial bones of corresponding lengths can be placed between the particles as spacer blocks 7. On the one hand, the push rod 9 plays a pushing role when the radioactive particles 6 are inserted. On the other hand, when the sleeve 5 is withdrawn, the push rod 9 can be used to press against the end radioactive particles 6 and slowly pull the sleeve 5 outward.
[0026] Each second cavity 104 is provided with a mounting hole 8 at one end of the end cap, into which the sleeve 5 is movably inserted. The open end of the sleeve 5, located outside the double-layer mesh bag 1, has a trumpet-shaped flared structure. This trumpet-shaped flared structure facilitates the insertion of the radioactive particles 6 and the spacer 7. It should be noted that the mounting holes 8 can be sealed after the bone cement 10 is injected, so no further treatment is required.
[0027] Example 2 Combine Figure 1 This embodiment provides a method for placing radioactive particles into a mesh bag for vertebroplasty, comprising the following steps: Step 1, select the mesh bag model according to clinical needs, that is, arrange the second cavity 104 of the double-layer mesh bag 1 evenly, at intervals or on one side to make different forms of mesh bags, so as to flexibly adjust the distribution of radioactive particles 6 according to the size and location of the lesion, improve the accuracy of radiotherapy, reduce damage to surrounding normal tissues, and achieve individualized treatment.
[0028] Step 2: Load the second cavities 104 of the double-layer mesh bag 1 with the number of radioactive particles 6 that matches the treatment plan. The radioactive particles 6 are placed one by one into the open end of the cannula 5 and pushed into the cannula 5 using the push rod 9. Spacers 7 are placed between the radioactive particles 6 when necessary. This operation allows for precise control of the number and distribution of radioactive particles 6 within each double-layer mesh bag 1 according to the treatment plan. The radioactive particles 6 are introduced sequentially along the axial direction of the cannula 5 in a single queue, forming an orderly array of particles within the cannula.
[0029] After the filling is completed, the push rod 9 is used to press against the end radioactive particles 6, and the sleeve 5 is slowly pulled outward so that the radioactive particles 6 remain in the second cavity 104 of the double-layer mesh bag 1. This can ensure that the radioactive particles 6 are accurately placed in the predetermined position, avoid displacement in subsequent operations, ensure the accuracy of the radiotherapy dose, and thus improve the treatment effect.
[0030] Step 3: Perform standard vertebroplasty procedures. Establish a bone puncture working channel and insert the mesh bag loaded with radioactive particles 6 through the working channel into the target vertebral area. X-ray fluoroscopy is used to confirm that the front end 105 of the mesh bag and the rear end internal and external injection tubes 3 and 4 are clearly visible, and that the mesh bag is fully extended from the working cannula 5. This X-ray confirmation allows for real-time observation of the mesh bag's position and status, ensuring accurate placement of the mesh bag at the lesion site. It also prevents incomplete extension of the mesh bag from effectively releasing the radioactive particles 6, ensuring precise targeting of the radiotherapy. It is important to note that after the mesh bag is accurately implanted, the core needle 2 must be removed. Furthermore, the working cannula used in vertebroplasty is common knowledge, and further description of the working cannula is omitted here.
[0031] Step 4: Connect a dedicated syringe and slowly inject bone cement 10 into the first cavity 103 of the double-layer mesh bag 1 through the inner injection tube 3. The double-layer mesh bag 1 gradually expands as the cement is injected, and the radioactive particles 6, constrained by the outer mesh 102, are uniformly distributed around the lesion. The expansion properties of the bone cement 10 cause the double-layer mesh bag 1 to expand, while the restraining effect of the outer mesh 102 allows the radioactive particles 6 to be evenly distributed around the lesion.
[0032] A small amount of bone cement 10 diffuses through the mesh of inner mesh 101 into outer mesh 102, where it engages with spacer 7 to secure radioactive particles 6 in their predetermined positions, preventing them from shifting or falling out during treatment. Because stable particle positioning is key to ensuring accurate radiotherapy doses and consistent therapeutic effects, this improves the safety and reliability of treatment.
[0033] Step 5: Release the fixed connection of the injection connection mechanism to the mesh bag, and sequentially remove the inner injection tube 3 and the outer injection tube 4. Since the injection connection mechanism is clamped and connected to the double-layer mesh bag 1, it can be quickly disassembled to reduce tissue damage.
[0034] Step 6: The radioactive particles 6 in the second cavity 104 of the double-layer mesh bag 1 are brought into close contact with the lesion area, and targeted radiotherapy begins immediately. The mesh bag can protect the surrounding normal tissues to the greatest extent possible and reduce the adverse reactions caused by radiotherapy.
[0035] Step 7: Local bandage, and the operation is completed.
[0036] This method of use can flexibly adjust the distribution of radioactive particles 6 according to the characteristics of the lesion, and fix the position of the radioactive particles 6 with the help of bone cement 10 to ensure that the radiation accurately acts on the lesion tissue. It can not only accurately locate the disease, but also reduce radiation to normal tissue, thereby improving the safety and effectiveness of treatment.
[0037] The above detailed description of the specific embodiments of the present invention is provided in conjunction with the drawings, but the present invention is not limited to the described embodiments. It is apparent to those skilled in the art that various changes, modifications, substitutions, and variations of these embodiments may be made without departing from the principles and spirit of the present invention, and these changes and modifications still fall within the scope of protection of the present invention.
Claims
1. Radioactive particles are placed in a mesh bag for vertebroplasty, characterized by: The invention comprises a double-layer mesh bag (1), wherein the double-layer mesh bag (1) comprises an inner mesh body (101) and an outer mesh body (102) which are connected inside and outside, wherein the inner mesh body (101) encloses a first cavity (103), and the inner mesh body (101) and the outer mesh body (102) are spaced and joined to form a plurality of second cavities (104) arranged circumferentially; one end of the first cavity (103) and the second cavity (104) on the same side is closed by an end cap (105), and the other end is used to inject bone cement (10) into the first cavity (103) through an injection connection mechanism; and radioactive particles (6) are placed in the second cavity (104) through an insertion mechanism.
2. The radioactive particle placement mesh bag for vertebroplasty according to claim 1, characterized in that: The end head (105) is fixed in the first cavity (103), and the end head (105) extends out of the first cavity (103) at one axial end and circumferentially fixes the edges of the inner mesh body (101) and the outer mesh body (102); a baffle (106) is provided at the extended end of the end head (105), and the baffle (106) is used to restrict the inner mesh body (101) and the outer mesh body (102) on the end head (105).
3. The radioactive particle placement mesh bag for vertebroplasty according to claim 2, characterized in that: The injection connection mechanism comprises an inner injection tube (3) and an outer injection tube (4), wherein the inner injection tube (3) is sleeved inside the inner mesh body (101) and communicates with the first cavity (103), and the outer injection tube (4) is sleeved outside the outer mesh body (102); an end of the terminal (105) close to the injection connection mechanism is connected to a core needle (2), and an end of the core needle (2) away from the terminal (105) is passed through the first cavity (103) and out of the inner injection tube (3).
4. The radioactive particle placement mesh bag for vertebroplasty according to claim 3, characterized in that: The edges of the inner mesh body (101) and the outer mesh body (102) at one end of the injection connection mechanism are bonded to each other and clamped between the inner injection tube (3) and the outer injection tube (4).
5. The radioactive particle placement mesh bag for vertebroplasty according to claim 1, characterized in that: The insertion mechanism comprises a sleeve (5) and a push rod (9). The sleeve (5) is a tubular structure with two ends open. The sleeve (5) is movably arranged in the second cavity (104), and one end extends out of the double-layer mesh bag (1). The push rod (9) is used to push the radioactive particles (6) into the sleeve (5).
6. The radioactive particle placement mesh bag for vertebroplasty according to claim 5, characterized in that: The radioactive particles (6) are arranged axially in a single row within the sleeve (5), and spacer blocks (7) are provided between the radioactive particles (6).
7. The radioactive particle placement mesh bag for vertebroplasty according to claim 5, characterized in that: Each second cavity (104) is provided with a mounting hole (8) at one end of the end head, and the sleeve (5) is movably inserted into the mounting hole (8); the open end of the sleeve (5) located outside the double-layer mesh bag (1) is a trumpet-shaped expansion structure.
8. The method for using the mesh bag for placement of radioactive particles for vertebroplasty according to any one of claims 1 to 7, characterized in that: The steps include: Step 1: Select the mesh bag model according to clinical needs; Step 2, using an inserting mechanism to load the second cavity (104) of the double-layer mesh bag (1) with the number of radioactive particles (6) that matches the treatment plan one by one; after loading is completed, removing the inserting mechanism; Step 3: Perform standard vertebroplasty operations, establish a bone puncture working channel, and implant the mesh bag loaded with radioactive particles (6) into the target area of the vertebral body through the working channel, with the mesh bag fully extended out of the vertebroplasty working cannula (5); Step 4, connecting a dedicated syringe, slowly injecting bone cement (10) into the first cavity (103) of the double-layer mesh bag (1) through the injection connection mechanism, the double-layer mesh bag (1) gradually expands as the bone cement (10) is injected, and a small amount of bone cement (10) diffuses through the mesh of the inner mesh body (101) to the outer mesh body (102), fixing the radioactive particles (6) at a predetermined position; Step 5, releasing the fixed connection of the injection connection mechanism to the double-layer mesh bag (1), and removing the injection connection mechanism; Step 6, the radioactive particles (6) in the second cavity (104) of the double-layer mesh bag (1) are brought into close contact with the lesion area, and targeted radiotherapy begins immediately; Step 7: Local bandage, and the operation is completed.