Composition for improving scalp and hair health of pets and application thereof

Abstract

The invention discloses a composition for improving pet scalp and hair health and application thereof, and belongs to the technical field of pet washing and care. The composition is prepared from the following components in parts by mass: 60 to 75 parts of water, 3 to 8 parts of mesoporous carbon loaded polysaccharide, 1 to 3 parts of a cationic surfactant, 3 to 5 parts of an ampholytic surfactant, 5 to 8 parts of glycerol, 0.5 to 1 part of panthenol, 0.1 to 0.3 part of rosa canina fruit extract, 0.05 to 0.15 part of annona squamosa seed extract, 0.05 to 0.2 part of African amomum kravanh seed extract, 0.1 to 0.3 part of herba schizonepetae extract and 0.01 to 0.1 part of citrus medica essential oil. The cleaning agent is prepared from the following components in parts by weight: 0.1 to 0.3 part of octanoyl hydroxamic acid, 0.5 to 1 part of 1, 2-hexanediol, 0.1 to 0.3 part of p-hydroxyacetophenone, 0.05 to 0.2 part of essence, 0.1 to 0.5 part of preservative, 0.5 to 2 parts of thickening agent, 0.1 to 0.5 part of sodium citrate and 0.5 to 1 part of sodium chloride. Sphingosine is adopted for covalently modifying mesoporous carbon, the adhesive force of components on pet scalp and hair is remarkably improved through hydrogen bond anchoring and lipid layer insertion effects, the three-dimensional pore channel structure of the mesoporous carbon can efficiently load active substances such as fucoidin and centella asiatica polysaccharide, and therefore the residence time of the active substances is prolonged.

Description

Technical Field

[0001] The present invention belongs to the technical field of pet washing and care, and in particular relates to a composition for improving the health of a pet's scalp and hair and an application thereof. Background Art

[0002] With economic development and rising incomes, pets have become an emotional support and life companion for modern families. Consumer demand for pet care products has evolved beyond basic cleaning. Pet owners are not only concerned with the effectiveness of products for hair cleansing, but also prioritize the mildness of ingredients and comprehensive care for the scalp microbiome and hair regeneration cycle. For example, pets' fragile skin barrier and rapid hair turnover cycle require care products to incorporate multi-dimensional benefits such as antibacterial, anti-inflammatory, and barrier repair. Today, multi-functional pet care products are becoming mainstream. For example, a formula containing tea tree oil and oat protein can reduce dandruff residue by 67%, while natural eucalyptus extract effectively removes mites by disrupting their cell membranes, while being less irritating than traditional permethrin ingredients. Targeting the specific characteristics of pet hair regeneration cycles, multi-component, all-in-one formulas combine antibacterial, moisturizing, and softening properties to meet pet owners' needs for convenience and comprehensive care.

[0003] The invention patent with publication number CN119606803A discloses a pet bathing lotion with natural plant extract for repelling insects and health care and its preparation method. The pet bathing lotion with natural plant extract for repelling insects and health care comprises the following components by mass: 2-8 parts of surfactant, 10-15 parts of moisturizer, 0.1-0.2 parts of pH adjuster, 2-10 parts of natural plant extract and 70-90 parts of water. The invention can achieve cleaning care, calming health care, anti-inflammatory and analgesic effects and repellent effects on pets. For example, the invention patent with publication number CN109833239A discloses a multifunctional pet shower gel and its preparation method. The multifunctional pet shower gel is prepared from the following raw materials in mass fractions: 5-20 parts of soap bean stock solution, 2-4 parts of glycerin, 70-85 parts of rose hydrosol, 1-2 parts of angelica dahurica, 2-3 parts of sweet almond oil, and 10-15 parts of PHMB. The invention not only cleans the pet's fur, but also moisturizes the skin, makes the fur shiny, soft and easy to comb, removes body odor from the pet's fur, inhibits the growth of bacteria, and can expel parasites on the pet's body while bathing. The use of natural plant extracts in pet care products can achieve deodorization, insect removal, and sterilization effects. At the same time, it has low irritation to pets and is not likely to cause allergies or inflammation in pets. However, the above invention and the pet care products of the prior art all have the problem that the effective ingredients are easily lost and difficult to stay on the skin surface for a long time. Therefore, it is difficult to achieve the effects of long-term care, insect repellent, and sterilization. Summary of the Invention

[0004] In response to the above situation, in order to overcome the defects of the existing technology, the present invention adopts a mesoporous carbon substrate with carboxylation-sphingosine dual modification technology, which significantly improves the adhesion of components on the pet's scalp and hair through hydrogen bond anchoring and lipid layer insertion. At the same time, the three-dimensional pore structure of mesoporous carbon can efficiently load active substances such as fucoidan and Centella asiatica polysaccharide, thereby increasing the residence time of effective substances.

[0005] In order to achieve the above-mentioned object, the following technical scheme is adopted: On the one hand, the present invention provides a composition for improving the health of pet scalp and hair, which is composed of the following components in parts by weight: 60-75 parts of water, 3-8 parts of mesoporous carbon-supported polysaccharide, 1-3 parts of cationic surfactant, 3-5 parts of amphoteric surfactant, 5-8 parts of glycerin, 0.5-1 parts of panthenol, 0.1-0.3 parts of dog rose fruit extract, and 0.05-0. 15 parts, African cardamom seed extract 0.05-0.2 parts, schizonepeta extract 0.1-0.3 parts, golden bergamot essential oil 0.01-0.1 parts, caprylhydroxamic acid 0.1-0.3 parts, 1,2-hexanediol 0.5-1 parts, p-hydroxyacetophenone 0.1-0.3 parts, flavor 0.05-0.2 parts, preservative 0.1-0.5 parts, thickener 0.5-2 parts, sodium citrate 0.1-0.5 parts and sodium chloride 0.5-1 parts.

[0006] Rosa canina fruit extract is rich in vitamin C, vitamin E, and various minerals. Vitamin C, a powerful antioxidant, neutralizes free radicals in your pet's scalp, reducing oxidative stress damage to hair follicle cells and providing a healthy growth environment for them. Vitamin E improves blood circulation in the scalp, ensuring adequate nutrients for hair follicles and promoting keratin synthesis, making hair stronger and reducing breakage and shedding. It also stimulates the activity of hair follicle stem cells, accelerating the hair growth cycle and promoting thicker fur.

[0007] Key components of Nepeta extract, such as nepetalactone, have a significant repellent effect against common pet parasites such as mites, fleas, and ticks. These components interfere with the parasites' nervous systems, making it difficult for them to attach and survive on pets' hair and skin. Furthermore, the distinctive scent of Golden Buddha's Hand essential oil further enhances this repellent effect, providing long-lasting protection for pets and reducing skin inflammation and other health issues caused by parasite bites.

[0008] An imbalance in oil production on your pet's scalp can lead to greasy, dull, and easily stained fur. Annona mume seed extract and Afroleum cardamomum seed extract contain several bioactive ingredients that regulate the function of sebaceous glands on the scalp. When the scalp's oil production is excessive, these ingredients inhibit excessive secretion; when it's insufficient, they stimulate sebaceous glands, thereby maintaining a dynamic balance of oil production on the scalp and keeping your pet's fur fresh and smooth.

[0009] The complex system composed of octanoylhydroxamic acid, 1,2-hexanediol and parahydroxyacetophenone not only has antibacterial effects on its own, but can also effectively inhibit the growth and reproduction of common Gram-positive bacteria, Gram-negative bacteria, fungi and other microorganisms. At the same time, combined with the soothing prickly pear cactus polysaccharides and Centella asiatica polysaccharides, while inhibiting harmful microorganisms, it can also relieve scalp discomfort caused by microbial infection or other reasons, and reduce symptoms such as itching, redness and swelling.

[0010] Furthermore, the mesoporous carbon-loaded polysaccharide is prepared by the following steps:

[0011] (1) Immersing the mesoporous carbon substrate in 65% concentrated nitric acid and refluxing for 6-8 hours for carboxylation treatment, then washing the mesoporous carbon substrate with deionized water and drying to obtain carboxylated mesoporous carbon, then adding it together with phytosphingosine into a PBS buffer solution at pH = 6.0, then adding EDC and NHS, reacting at 40-50°C for 24-36 hours, centrifuging and purifying, and freeze-drying to obtain sphingosine covalently modified mesoporous carbon;

[0012] (2) The polysaccharide composition is dissolved in deionized water to prepare a mixed polysaccharide solution with a mass fraction of 5%, the sphingosine covalently modified mesoporous carbon is immersed in the polysaccharide solution, and ultrasonic assisted adsorption is performed at 50-60°C and 200-500W power for 6-8 hours, followed by vacuum freeze drying, and the freeze-dried product is immersed in a sodium alginate solution with a mass fraction of 0.1%, and a 0.5 mol / L CaCl2 solution is added for cross-linking for 30 minutes. After washing with deionized water, vacuum freeze drying is performed to obtain the mesoporous carbon-loaded polysaccharide.

[0013] Furthermore, in step (1), the mass ratio of the mesoporous carbon substrate to concentrated sulfuric acid is 1:15-30; and the mass ratio of the carboxylated mesoporous carbon, phytosphingosine, PBS buffer, EDC, and NHS in step (1) is 1:0.2-0.5:50-100:0.05-0.1:0.05-0.1.

[0014] Furthermore, the polysaccharide composition in step (2) is composed of the following components in parts by mass: 25-35 parts of fucoidan, 15-25 parts of tremella polysaccharide, 10-20 parts of opuntia polysaccharide, 10-20 parts of oat β-glucan, 5-15 parts of Centella asiatica polysaccharide and 5-10 parts of chitosan oligosaccharide.

[0015] Furthermore, in the step (2), the mass ratio of the mixed polysaccharide solution and the sphingosine covalently modified mesoporous carbon is 2:5-1; and the mass ratio of the freeze-dried product, the sodium alginate solution and the CaCl2 solution in the step (2) is 1:10-20:1-3.

[0016] Furthermore, the mesoporous carbon substrate is prepared using bamboo fiber or coconut shell as a raw material.

[0017] Furthermore, the cationic surfactant is a combination of one or more of polyquaternium-10, quaternium-80, behenyltrimethylammonium chloride, hexadecyltrimethylammonium methylsulfate, stearyltrimethylammonium chloride, dodecyldimethylbenzylammonium chloride and distearylhydroxyethyl methylsulfate.

[0018] Furthermore, the amphoteric surfactant is a combination of one or more of lauramidopropyl betaine, cocamidopropyl betaine, cocamidopropyl hydroxysulfonate, cocamidopropyl PG-dimethylammonium chloride phosphate, disodium lauroamphodiacetate, sodium cocoamphoacetate and disodium cocoamphodiacetate.

[0019] Furthermore, the preservative is a combination of one or more of phenoxyethanol, potassium sorbate, ethylhexylglycerin, sodium benzoate and sodium dehydroacetate.

[0020] Furthermore, the thickener is a combination of one or more of casein, xanthan gum, carbomer, xanthan gum, hydroxyethyl cellulose and ethylene acrylate copolymer.

[0021] On the other hand, the present invention also provides an application of the composition for improving the health of a pet's scalp and hair, that is, applying the composition to bathing and caring for a pet.

[0022] The beneficial effects of the present invention are:

[0023] (1) The present invention realizes the covalent modification of mesoporous carbon with sphingosine by condensing the carboxyl group of mesoporous carbon with the amino group of sphingosine. The hydroxyl group of plant sphingosine forms hydrogen bonds with pet hair and scalp keratin due to its similar structure to ceramide and cholesterol ester in the stratum corneum, providing alkyl chains to insert into the lipid layer, significantly enhancing the anchoring effect of the mesoporous carbon, reducing the loss of effective ingredients, and providing a guarantee for the continuous efficacy of the polysaccharide compound. At the same time, the mesoporous carbon has a rich mesoporous structure and absorbs a large amount of polysaccharide composition and slowly releases it, prolonging the residence time of the polysaccharide. Among them, the polar groups of fucoidan enhance the adsorption of hair dirt to improve the cleaning power, Tremella polysaccharide can form a film to moisturize and enhance the gloss of pet hair, prickly pear cactus polysaccharide and Centella asiatica polysaccharide contain active ingredients such as flavonoids and terpenes, which inhibit the release of inflammatory factors, anti-inflammatory repair, soothe the scalp, and prevent sensitivity, oat β-glucan and chitosan oligosaccharide can regulate cell signal transduction, promote cell proliferation and differentiation, enhance the skin barrier, and change the permeability of bacterial and fungal cell membranes to inhibit their growth.

[0024] (2) Vitamin C in dog rose fruit extract neutralizes free radicals and reduces oxidative damage to hair follicle cells. Vitamin E improves blood circulation in the scalp, promotes hair keratin synthesis, and stimulates the activity of hair follicle stem cells, making hair strong, growing faster and thicker. Nepetalactone and other ingredients in schizonepeta extract interfere with the parasite nervous system. The special smell of golden bergamot essential oil forms an insect repellent aura, which together play a role in repelling mites and other parasites, reducing health problems such as skin inflammation caused by mites. The bioactive ingredients of Annona mume seed extract and African cardamom seed extract can regulate the function of scalp sebaceous gland cells, maintain the dynamic balance of oil secretion, and ensure that the hair is fresh and smooth. Caprylhydroxamic acid, 1,2-hexanediol and parahydroxyacetophenone form a composite antibacterial system, which synergistically inhibits Gram-positive bacteria, Gram-negative bacteria and fungi and other microorganisms. Combined with prickly pear cactus polysaccharides and Centella asiatica polysaccharides, it relieves pets' scalp discomfort and reduces itching and redness. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 The antibacterial effect test results of the compositions of various embodiments and comparative examples of the present invention are shown in FIG.

[0026] Figure 2 The following are the mite killing test results of the compositions of various embodiments and comparative examples of the present invention;

[0027] Figure 3 The following are the evaluation results of the health of pet hair after washing and caring with the compositions of various embodiments of the present invention and comparative examples.

[0028] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0030] Unless otherwise defined, all technical and scientific terms used herein have the same meanings as those familiar to those skilled in the art. Furthermore, any methods and materials similar or equivalent to those described herein can be applied to the present invention. The preferred embodiments and materials described herein are for illustrative purposes only and are not intended to limit the scope of this application.

[0031] The experimental methods in the following examples, unless otherwise specified, are all conventional methods, and the experimental materials used in the following examples, unless otherwise specified, are all purchased from commercial channels.

[0032] Example 1

[0033] Composition for improving pet scalp and hair health

[0034] The composition is composed of the following components in parts by mass: 60 parts of water, 3 parts of mesoporous carbon-supported polysaccharide, 1 part of a cationic surfactant (composed of polyquaternium-10, quaternium-80, and dodecyldimethylbenzyl ammonium chloride in a mass ratio of 3:2:1), 3 parts of an amphoteric surfactant (composed of lauramidopropyl betaine, cocamidopropyl betaine, and cocamidopropyl hydroxysulfonyl betaine in a mass ratio of 1:2:1), 5 parts of glycerin, 0.5 parts of panthenol, 0.1 parts of dog rose fruit extract, and Annona chebula seed. 0.05 parts of extract, 0.05 parts of African cardamom seed extract, 0.1 parts of schizonepeta extract, 0.01 parts of golden bergamot essential oil, 0.1 parts of caprylhydroxamic acid, 0.5 parts of 1,2-hexanediol, 0.1 parts of p-hydroxyacetophenone, 0.05 parts of flavor, 0.1 parts of preservatives (composed of phenoxyethanol, potassium sorbate, and sodium benzoate in a mass ratio of 2:1:1), 0.5 parts of thickener (composed of casein, xanthan gum, and carbomer in a mass ratio of 1:3:1), 0.1 parts of sodium citrate and 0.5 parts of sodium chloride.

[0035] The mesoporous carbon-loaded polysaccharide is prepared by the following steps:

[0036] (1) The mesoporous carbon substrate (prepared from bamboo fiber) was immersed in concentrated nitric acid with a mass fraction of 65%, and the mass ratio of the mesoporous carbon substrate to concentrated sulfuric acid was 1:15. The substrate was refluxed for 6 hours for carboxylation treatment. The mesoporous carbon substrate was then washed with deionized water and dried to obtain carboxylated mesoporous carbon. The carbon was then added to a PBS buffer solution with a pH of 6.0 together with phytosphingosine. The mass ratio of carboxylated mesoporous carbon, phytosphingosine, PBS buffer solution, EDC and NHS was 1:0.2:50:0.05:0.05. The reaction was carried out at 40°C for 24 hours. The carbon was purified by centrifugation and freeze-dried to obtain sphingosine covalently modified mesoporous carbon.

[0037] (2) The polysaccharide composition was dissolved in deionized water to prepare a mixed polysaccharide solution with a mass fraction of 5%. The polysaccharide composition consisted of the following components in mass parts: 25 parts of fucoidan, 15 parts of tremella polysaccharide, 10 parts of prickly pear cactus polysaccharide, 10 parts of oat β-glucan, 5 parts of Centella asiatica polysaccharide and 5 parts of chitosan oligosaccharide. The mass ratio of the mixed polysaccharide solution to sphingosine covalently modified mesoporous carbon was 2:5. The mixture was subjected to ultrasonic assisted adsorption at 50°C and 200W power for 6 hours, followed by vacuum freeze-drying. The freeze-dried product was immersed in a sodium alginate solution with a mass fraction of 0.1%. The mass ratio of the freeze-dried product, sodium alginate solution and CaCl2 solution was 1:10:1. 0.5 mol / L CaCl2 solution was added for cross-linking for 30 minutes. After washing with deionized water, the mixture was vacuum freeze-dried to obtain the mesoporous carbon-loaded polysaccharide.

[0038] Example 2

[0039] Composition for improving pet scalp and hair health

[0040] The composition is composed of the following components in parts by mass: 75 parts of water, 8 parts of mesoporous carbon-supported polysaccharide, 3 parts of a cationic surfactant (composed of behenyltrimethylammonium chloride, hexadecyltrimethylammonium methylsulfate, and stearyltrimethylammonium chloride in a mass ratio of 1:3:1), 5 parts of an amphoteric surfactant (composed of cocamidopropyl hydroxysulfobetaine, sodium cocamidopropyl PG-dimethylammonium chloride phosphate, and disodium lauroamphodiacetate in a mass ratio of 3:1:1), 8 parts of glycerin, 1 part of panthenol, and 0.01% glycerin. .3 parts, custard apple seed extract 0.15 parts, African cardamom seed extract 0.2 parts, schizonepeta extract 0.3 parts, golden bergamot essential oil 0.1 parts, caprylhydroxamic acid 0.3 parts, 1,2-hexanediol 1 part, p-hydroxyacetophenone 0.3 parts, essence 0.2 parts, preservative 0.5 parts (consisting of ethylhexylglycerin, sodium benzoate, sodium dehydroacetate in a mass ratio of 1:2:2), thickener 2 parts (consisting of carbomer, xanthan gum, hydroxyethyl cellulose in a mass ratio of 2:1:2), 0.5 parts of sodium citrate and 1 part of sodium chloride.

[0041] The mesoporous carbon-loaded polysaccharide is prepared by the following steps:

[0042] (1) The mesoporous carbon substrate (prepared from coconut shell) was immersed in concentrated nitric acid with a mass fraction of 65%, and the mass ratio of the mesoporous carbon substrate to concentrated sulfuric acid was 1:30. The substrate was refluxed for 8 hours for carboxylation treatment. The mesoporous carbon substrate was then washed with deionized water and dried to obtain carboxylated mesoporous carbon. The carbon was then added to a PBS buffer solution with a pH of 6.0 together with phytosphingosine. The mass ratio of carboxylated mesoporous carbon, phytosphingosine, PBS buffer solution, EDC and NHS was 1:0.5:100:0.1:0.1. The reaction was carried out at 50°C for 36 hours. After purification by centrifugation, the carbon was freeze-dried to obtain sphingosine covalently modified mesoporous carbon.

[0043] (2) The polysaccharide composition was dissolved in deionized water to prepare a mixed polysaccharide solution with a mass fraction of 5%. The polysaccharide composition consisted of the following components in mass parts: 35 parts of fucoidan, 25 parts of tremella polysaccharide, 20 parts of prickly pear cactus polysaccharide, 20 parts of oat β-glucan, 15 parts of Centella asiatica polysaccharide and 10 parts of chitosan oligosaccharide. The mass ratio of the mixed polysaccharide solution to sphingosine covalently modified mesoporous carbon was 2:1. The mixture was subjected to ultrasonic assisted adsorption at 60°C and 500W power for 8h, followed by vacuum freeze-drying. The freeze-dried product was immersed in a sodium alginate solution with a mass fraction of 0.1%. The mass ratio of the freeze-dried product, sodium alginate solution and CaCl2 solution was 1:20:3. 0.5 mol / L CaCl2 solution was added for cross-linking for 30min. After washing with deionized water, the mixture was vacuum freeze-dried to obtain the mesoporous carbon-loaded polysaccharide.

[0044] Example 3

[0045] Composition for improving pet scalp and hair health

[0046] The composition is composed of the following components in parts by mass: 68 parts of water, 5 parts of mesoporous carbon-supported polysaccharide, 2 parts of a cationic surfactant (composed of stearyltrimethylammonium chloride, dodecyldimethylbenzylammonium chloride, and distearylhydroxyethylmethylammonium sulfate in a mass ratio of 1:3:2), 4 parts of an amphoteric surfactant (composed of disodium lauroamphodiacetate, sodium cocoamphoacetate, and disodium cocoamphodiacetate in a mass ratio of 2:1:2), 6.5 parts of glycerin, 0.75 parts of panthenol, and 0.2 parts of Rosa canina fruit extract. , 0.1 part of custard apple seed extract, 0.12 part of African cardamom seed extract, 0.2 part of schizonepeta extract, 0.05 part of golden bergamot essential oil, 0.2 part of caprylhydroxamic acid, 0.75 part of 1,2-hexanediol, 0.2 part of p-hydroxyacetophenone, 0.12 part of flavor, 0.3 part of preservative (composed of phenoxyethanol, potassium sorbate, and ethylhexylglycerin in a mass ratio of 3:1:2), 1.2 parts of thickener (composed of casein, xanthan gum, and carbomer in a mass ratio of 1:2:2), 0.3 part of sodium citrate and 0.75 part of sodium chloride.

[0047] The mesoporous carbon-loaded polysaccharide is prepared by the following steps:

[0048] (1) The mesoporous carbon substrate (prepared from bamboo fiber) was immersed in concentrated nitric acid with a mass fraction of 65%, and the mass ratio of the mesoporous carbon substrate to concentrated sulfuric acid was 1:22. The solution was refluxed for 7 hours for carboxylation treatment. The mesoporous carbon substrate was then washed with deionized water and dried to obtain carboxylated mesoporous carbon. The carbon was then added to a PBS buffer solution with a pH of 6.0 together with phytosphingosine. The mass ratio of carboxylated mesoporous carbon, phytosphingosine, PBS buffer solution, EDC and NHS was 1:0.35:75:0.075:0.075. The solution was reacted at 45°C for 30 hours, purified by centrifugation and freeze-dried to obtain sphingosine covalently modified mesoporous carbon.

[0049] (2) The polysaccharide composition was dissolved in deionized water to prepare a mixed polysaccharide solution with a mass fraction of 5%. The polysaccharide composition consisted of the following components in mass parts: 30 parts of fucoidan, 20 parts of tremella polysaccharide, 15 parts of prickly pear cactus polysaccharide, 15 parts of oat β-glucan, 10 parts of Centella asiatica polysaccharide and 7.5 parts of chitosan oligosaccharide. The mass ratio of the mixed polysaccharide solution to sphingosine covalently modified mesoporous carbon was 2:3. The mixture was subjected to ultrasonic assisted adsorption at 55°C and 350W power for 7h, and then vacuum freeze-dried. The freeze-dried product was immersed in a sodium alginate solution with a mass fraction of 0.1%. The mass ratio of the freeze-dried product, sodium alginate solution and CaCl2 solution was 1:15:2. 0.5 mol / L CaCl2 solution was added for cross-linking for 30min. After washing with deionized water, the mixture was vacuum freeze-dried to obtain the mesoporous carbon-loaded polysaccharide.

[0050] Example 4

[0051] Composition for improving pet scalp and hair health

[0052] The cationic surfactant in this embodiment is composed of polyquaternium-10, quaternium-80, and behenyltrimethylammonium chloride in a mass ratio of 2:1:2, and the amphoteric surfactant is composed of cocamidopropyl betaine, cocamidopropyl hydroxysulfonyl betaine, and disodium lauroamphodiacetate in a mass ratio of 1:3:1, and the rest are the same as in Example 3.

[0053] Example 5

[0054] Composition for improving pet scalp and hair health

[0055] The cationic surfactant in this embodiment is composed of dodecyldimethylbenzyl ammonium chloride, stearyltrimethylammonium chloride, and distearylhydroxyethylmethylammonium sulfate in a mass ratio of 3:1:1, and the amphoteric surfactant is composed of sodium lauroylamphoacetate, disodium cocoamphodiacetate, and sodium cocamidopropyl PG-dimethylammonium chloride phosphate in a mass ratio of 1:2:2. The rest are the same as in Example 3.

[0056] Example 6

[0057] Composition for improving pet scalp and hair health

[0058] In this embodiment, the preservative is composed of phenoxyethanol, potassium sorbate, and sodium benzoate in a mass ratio of 1:1:3, and the rest are the same as in Example 3.

[0059] Comparative Example 1

[0060] In this comparative example, phytosphingosine is not used to covalently modify the mesoporous carbon. That is, an equal amount of mesoporous carbon substrate is used to replace sphingosine to covalently modify the mesoporous carbon for step (2) to load the polysaccharide. The rest is the same as Example 3.

[0061] Comparative Example 2

[0062] The sugar composition in this comparative example only retained oat β-glucan and chitosan oligosaccharide, and the rest were the same as those in Example 3.

[0063] Comparative Example 3

[0064] The composition of the composition in this comparative example does not contain Rosa canina fruit extract, and the rest is the same as that of Example 3.

[0065] Comparative Example 4

[0066] The composition of the composition in this comparative example does not contain Annona mume seed extract and Aframomum melegueta seed extract, and the rest is the same as that in Example 3.

[0067] Test Example 1

[0068] Safety evaluation of the composition

[0069] Male C57BL / 6 mice aged 6-8 weeks were selected, with 10 mice in each group. Before the experiment, the back of the neck of the mice was shaved and the composition of each example and comparative example was applied. After 30 minutes, the mice were washed with warm water. The necks of the mice were observed 1 hour and 24 hours after washing for the presence of erythema and edema. The results are shown in Table 1.

[0070] The results in Table 1 show that Examples 1-6 showed no erythema or edema 1 and 24 hours after application to the back of the neck of mice, while Comparative Example 3 showed erythema but no edema 24 hours later, demonstrating the superior safety of the compositions of the Examples. This is attributed to the synergistic effects of the various components in the Examples. The anti-inflammatory, repairing, and scalp-soothing effects of the various polysaccharides supported by the covalently modified mesoporous carbon with sphingosine reduce skin irritation.

[0071] Table 1 Safety evaluation results of the composition

[0072] time 1h 24h Example 1 No erythema or edema No erythema or edema Example 2 No erythema or edema No erythema or edema Example 3 No erythema or edema No erythema or edema Example 4 No erythema or edema No erythema or edema Example 5 No erythema or edema No erythema or edema Example 6 No erythema or edema No erythema or edema Comparative Example 1 No erythema or edema No erythema or edema Comparative Example 2 No erythema or edema No erythema or edema Comparative Example 3 No erythema or edema There is erythema but no edema Comparative Example 4 No erythema or edema No erythema or edema

[0073] Test Example 2

[0074] Evaluation of antibacterial effect of the composition

[0075] GB / T 20944.3-2008 oscillation method was used, with Staphylococcus aureus, Escherichia coli and Malassezia as the test strains. Wool fabrics were immersed in the solution of the composition of the embodiment and the comparative example, and cultured at a constant temperature of 37°C. The antibacterial rates were measured after 0 days, 1 day, 3 days and 7 days, respectively. The results are shown in FIG. Figure 1 .

[0076] The results of Test Example 2 show that the antibacterial rate of the composition of the embodiment against Staphylococcus aureus, Escherichia coli and Malassezia is higher than that of the comparative example at each time point. This is because the composite antibacterial system composed of octanoylhydroxamic acid, 1,2-hexanediol and parahydroxyacetophenone in the embodiment synergistically inhibits various microorganisms. At the same time, the polysaccharide component can also inhibit the release of inflammatory factors, creating an environment that is not conducive to the survival of microorganisms. The covalent modification of mesoporous carbon with sphingosine prolongs the residence time of the polysaccharide compound, so the antibacterial effect of the embodiment is better.

[0077] Test Example 3

[0078] Evaluation of the mite-killing effect of the composition

[0079] The mite killing rate of each group of examples and comparative examples after 24 hours and 72 hours was tested using the NY / T 1151.2-2006 test method. The results are shown in Figure 2 .

[0080] In Test Example 3, the mite-killing rate of the Example was higher than that of the Comparative Example after 24 and 72 hours. This is mainly due to the fact that the components of the Schizonepeta extract in the Example, such as nepetalactone, interfere with the parasite's nervous system, and the unique odor of the golden bergamot essential oil also has an insect repellent effect. The two work together to repel mites and other parasites, resulting in a better mite-killing effect in the Example.

[0081] Test Example 4

[0082] Evaluation of the cleaning and care effect of the composition

[0083] (1) Experimental groups:

[0084] Experimental group: using the compositions of the embodiments of the present invention and the comparative examples;

[0085] Control group: water treatment (basic cleaning only, no functional ingredients);

[0086] Sample size: 10 healthy adult pet dogs (same breed, similar age) and 10 healthy adult pet cats (same breed, similar age) were selected from each group at a pet center.

[0087] (2) Treatment method and detection time:

[0088] Treatment method: Follow the following steps each time: wet the hair, apply the shampoo evenly, massage for 5 minutes, rinse thoroughly, blow dry and comb;

[0089] Environmental control: uniform feeding conditions, living environment temperature and humidity (25±2℃, 50%±5%RH);

[0090] Sampling and testing time: 0h, 24h, 48h, 72h.

[0091] (3) Evaluation and scoring:

[0092] Cleanliness scoring: Ten independent observers observed the pet's skin cleanliness after washing and care (whether there was dander or dust) and scored it. No visible dirt was scored as 5 points, slight dirt was scored as 4 points, moderate dirt was scored as 3 points, obvious dirt was scored as 2 points, and severe dirt was scored as 1 point.

[0093] Moisture score: Ten independent observers judge the dryness / wetness of the pet's hair by touching it and scoring it. The hair is moist and elastic, with a score of 5 points; slightly dry but plastic, with a score of 4 points; obviously dry, with a score of 3 points; severely dry, with a score of 2 points; and brittle and easily broken, with a score of 1 point.

[0094] Lubricity score: Use a Furminator pet comb to comb a fixed length of hair, record the resistance value (N), and randomly select hair samples for scanning electron microscopy analysis of scale structural integrity. 5 points are assigned if the resistance is ≤0.5N and the scales are intact and tightly arranged; 4 points are assigned if the scales are slightly lifted and the resistance is 0.6-1.0N; 3 points are assigned if the scales are moderately damaged and the resistance is 1.1-1.5N; 2 points are assigned if the scales are extensively detached and the resistance is 1.6-2.0N; and 1 point is assigned if the scales are severely damaged and the resistance is >2.0N.

[0095] The above scoring results are shown in Table 2.

[0096] Table 2 Evaluation results of the cleaning and care effects of the compositions

[0097]

[0098] As can be seen from the table above, the Example scored higher than the Comparative Example and Control at 0, 12, 24, and 48 hours in terms of cleanliness, moisturizing, and lubricity. Regarding cleanliness, the polar groups of fucoidan enhance the adsorption of hair dirt, improving cleaning power; regarding moisturizing, Tremella fuciformis polysaccharide forms a film and moisturizes; and regarding lubricity, the synergistic effect of various ingredients protects the structural integrity of the hair scales. Therefore, the Example achieves superior cleaning and conditioning results.

[0099] Test Example 5

[0100] Evaluation of pet hair health after washing and caring with the composition

[0101] The instantaneous tensile force of the pet hair after washing and conditioning in each group of Example 4 was measured at 20°C and 45% relative humidity. Five hairs were taken from each pet sample in each group. The peak force at which the hair was pulled apart reflects the toughness and strength of the pet hair. Hair with good toughness and high strength has higher quality, indicating that the pet hair is in a higher health. The above results are shown in Table 1. Figure 3 .

[0102] Figure 3 As can be seen, the instantaneous tensile force of the pet's hair after washing and conditioning in the Example is higher, indicating better hair toughness and strength, indicating a healthier pet hair. This is because the vitamin C in the Rosa canina fruit extract neutralizes free radicals, while the vitamin E improves scalp blood circulation, promotes hair keratin synthesis, and stimulates hair follicle stem cell activity, strengthening hair. Therefore, the Example is more effective in improving the health of pet hair.

[0103] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

[0104] The present invention and its embodiments are described above. Such description is not restrictive. The drawings show only one embodiment of the present invention, and actual applications are not limited thereto. In short, if a person skilled in the art is inspired by the above, and does not deviate from the purpose of the present invention, any method and embodiment similar to the technical solution without creative design shall fall within the scope of protection of the present invention.

Claims

1. A composition for improving the health of a pet's scalp and hair, characterized by: The invention is composed of the following components in parts by mass: 60-75 parts of water, 3-8 parts of mesoporous carbon-supported polysaccharide, 1-3 parts of cationic surfactant, 3-5 parts of amphoteric surfactant, 5-8 parts of glycerin, 0.5-1 part of panthenol, 0.1-0.3 parts of Rosa canina fruit extract, 0.05-0.15 parts of Annona custardii seed extract, 0.05-0.2 parts of African cardamom seed extract, 0.1-0.3 parts of Nepeta tenuifolia extract, 0.01-0.1 parts of golden bergamot essential oil, 0.1-0.3 parts of caprylhydroxamic acid, 0.5-1 parts of 1,2-hexanediol, 0.1-0.3 parts of p-hydroxyacetophenone, 0.05-0.2 parts of fragrance, 0.1-0.5 parts of preservatives, 0.5-2 parts of thickener, 0.1-0.5 parts of sodium citrate and 0.5-1 parts of sodium chloride; The mesoporous carbon-loaded polysaccharide is prepared by the following steps: (1) Immersing the mesoporous carbon substrate in 65% concentrated nitric acid and refluxing for 6-8 hours for carboxylation treatment, then washing the mesoporous carbon substrate with deionized water and drying to obtain carboxylated mesoporous carbon, then adding it together with phytosphingosine into a PBS buffer solution at pH = 6.0, then adding EDC and NHS, reacting at 40-50°C for 24-36 hours, centrifuging and purifying, and freeze-drying to obtain sphingosine covalently modified mesoporous carbon; (2) The polysaccharide composition is dissolved in deionized water to prepare a mixed polysaccharide solution with a mass fraction of 5%, the sphingosine covalently modified mesoporous carbon is immersed in the polysaccharide solution, and ultrasonic assisted adsorption is performed at 50-60°C and 200-500W power for 6-8 hours, followed by vacuum freeze drying, and the freeze-dried product is immersed in a sodium alginate solution with a mass fraction of 0.1%, and a 0.5 mol / L CaCl2 solution is added for cross-linking for 30 minutes. After washing with deionized water, vacuum freeze drying is performed to obtain the mesoporous carbon-loaded polysaccharide.

2. The composition for improving the health of a pet's scalp and hair according to claim 1, characterized in that: The mass ratio of the mesoporous carbon substrate to concentrated sulfuric acid in the step (1) is 1:15-30; the mass ratio of the carboxylated mesoporous carbon, phytosphingosine, PBS buffer, EDC and NHS in the step (1) is 1:0.2-0.5:50-100:0.05-0.1:0.05-0.

1.

3. The composition for improving pet scalp and hair health according to claim 2, characterized in that: The polysaccharide composition in step (2) is composed of the following components in parts by mass: 25-35 parts of fucoidan, 15-25 parts of tremella polysaccharide, 10-20 parts of opuntia polysaccharide, 10-20 parts of oat β-glucan, 5-15 parts of Centella asiatica polysaccharide and 5-10 parts of chitosan oligosaccharide.

4. The composition for improving pet scalp and hair health according to claim 3, characterized in that: The mass ratio of the mixed polysaccharide solution and the sphingosine covalently modified mesoporous carbon in step (2) is 2:5-1; the mass ratio of the freeze-dried product, the sodium alginate solution and the CaCl2 solution in step (2) is 1:10-20:1-3.

5. The composition for improving pet scalp and hair health according to claim 4, characterized in that: The mesoporous carbon substrate is prepared by using bamboo fiber or coconut shell as a raw material.

6. The composition for improving pet scalp and hair health according to claim 5, characterized in that: The cationic surfactant is a combination of one or more of polyquaternium-10, quaternium-80, behenyltrimethylammonium chloride, hexadecyltrimethylammonium methylsulfate, stearyltrimethylammonium chloride, dodecyldimethylbenzyl ammonium chloride and distearylhydroxyethyl methylsulfate.

7. The composition for improving pet scalp and hair health according to claim 6, characterized in that: The amphoteric surfactant is a combination of one or more of lauroyl propyl betaine, cocamidopropyl betaine, cocamidopropyl hydroxysulfonyl betaine, sodium cocamidopropyl PG-dimethyl ammonium chloride phosphate, disodium lauroamphodiacetate, sodium cocoamphoacetate and disodium cocoamphodiacetate.

8. The composition for improving pet scalp and hair health according to claim 7, characterized in that: The preservative is a combination of one or more of phenoxyethanol, potassium sorbate, ethylhexylglycerin, sodium benzoate and sodium dehydroacetate.

9. The composition for improving pet scalp and hair health according to claim 8, characterized in that: The thickener is a combination of one or more of casein, xanthan gum, carbomer, xanthan gum, hydroxyethyl cellulose and ethylene acrylate copolymer.

10. Use of the composition for improving pet scalp and hair health according to any one of claims 1 to 9, characterized in that: The composition is applied to pet bathing and care.

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