Device capable of positioning space division radiotherapy collimator and use method

By designing a device with a fixing structure, a positioning structure, and a collimator-bearing structure, the problem of the existing technology in which high-dose irradiation sites cannot be accurately located is solved, repeated irradiation and precise evaluation of the same site are achieved, and subsequent histological analysis is supported.

CN120643847APending Publication Date: 2025-09-16THE THIRD PEOPLES HOSPITAL OF CHENGDU
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Patent Information

Application Number
CN202511058188.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-29
Publication Date
2025-09-16

AI Technical Summary

Technical Problem

Existing spatially fractionated radiotherapy devices are unable to accurately locate the specific site for high-dose irradiation, resulting in the inability to achieve repeated irradiation of the same site and subsequent histological analysis.

Method used

A device consisting of a fixing structure, a positioning structure, and a collimator supporting structure was designed. Accurate positioning and repeated irradiation were achieved through the correspondence between the observation hole of the transparent positioning structure and the irradiation window of the lead plate. Combined with the adjustment of the detachable penetrating plate and the supporting structure, the accuracy and stability of the radiation range were ensured.

Benefits of technology

It achieves accurate positioning and repeated irradiation of the same part, ensures precise assessment of the radiation coverage point, and supports subsequent histological analysis.

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Abstract

The invention discloses a device capable of positioning a space division radiotherapy collimator and a use method, and relates to the technical field of space division radiotherapy, the device comprises a fixing structure, a positioning structure and a collimator bearing structure which are arranged from bottom to top, the fixing structure is used for clamping a to-be-irradiated part, the positioning structure is a transparent structure, and the collimator bearing structure is used for bearing the collimator. The positioning structure is provided with an observation hole, the collimator bearing structure is a lead plate, the collimator bearing structure is provided with an irradiation window, the irradiation window is used for arranging a collimator, the observation hole corresponds to the irradiation window in position, and X-rays can irradiate a part to be irradiated through the collimator. According to the device capable of positioning the space division radiotherapy collimator, repeated irradiation on the same part can be realized, and accurate positioning can be realized.
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Description

Technical Field

[0001] The present invention relates to the technical field of spatial fractionation radiotherapy, and in particular to a device capable of positioning a spatial fractionation radiotherapy collimator and a method for using the collimator. Background Art

[0002] Spatial fractionation radiotherapy is a radiotherapy technique that delivers uneven irradiation to a tumor, requiring high-dose irradiation to a fixed location within the tumor rather than the entire tumor. Existing methods and equipment for spatial fractionation radiotherapy in mice can only deliver irradiation using a lead collimator, but cannot pinpoint the specific location of the high-dose irradiation. When spatial fractionation radiotherapy requires repeated irradiation of the same tumor site to achieve a high dose, existing devices / methods cannot pinpoint the specific location of the high-dose irradiation, making it impossible to repeat the irradiation of the specific high-dose site between two interval experiments. Summary of the Invention

[0003] The purpose of the present invention is to provide a device and a method for using a positionable spatially segmented radiotherapy collimator to solve the problems existing in the above-mentioned prior art, so as to achieve repeated irradiation of the same part and achieve accurate positioning.

[0004] To achieve the above object, the present invention provides the following solutions:

[0005] The present invention provides a device for a positionable spatially segmented radiotherapy collimator, comprising: a fixing structure, a positioning structure, and a collimator supporting structure arranged from bottom to top, wherein the fixing structure is used to clamp a part to be irradiated, the positioning structure is a transparent structure, and the positioning structure is provided with an observation hole, the collimator supporting structure is a lead plate, and the collimator supporting structure is provided with an irradiation window, and the irradiation window is used to set the collimator, and the positions of the observation hole and the irradiation window correspond to each other, so that X-rays can be irradiated on the part to be irradiated through the collimator.

[0006] In some specific schemes, the fixing structure includes two oppositely arranged first fixing components and two oppositely arranged second fixing components, the second fixing components are arranged perpendicular to the first fixing components, a first clamping plate is provided at the end of the first fixing component, a first marking protrusion is provided on the first clamping plate, and a second clamping plate is provided at the end of the second fixing component, and a second marking protrusion is provided on the second clamping plate.

[0007] In some specific schemes, the fixing structure also includes a fixing plate, an opening is provided at the center position of the fixing plate, the position of the opening corresponds to the position of the irradiation window, and the first clamping plate and the second clamping plate are both located at the opening; the first fixing component and the second fixing component have the same structure, the first fixing component and the second fixing component both include a screw, the screw is threadedly connected to the fixing plate, the first clamping plate or the second clamping plate is provided at one end of the screw, and a knob is provided at the other end of the screw.

[0008] In some specific embodiments, the positioning structure is a transparent plate.

[0009] In some specific schemes, a marking structure is further included, and a marking portion is provided at one end of the marking structure. The marking structure can pass through the observation hole, and the marking portion can contact the part to be irradiated to achieve marking of the irradiation point; the number, size and position of the observation hole and the through hole of the collimator are set correspondingly.

[0010] In some specific solutions, the positioning structure is provided with an observation window, and a transmission plate is provided at the observation window. The transmission plate is detachably connected to the positioning structure, and the observation hole is provided on the transmission plate.

[0011] In some specific embodiments, a base is further included, which is located below the fixed structure and has a scale set on it.

[0012] In some specific schemes, a supporting structure is further included, which is vertically arranged. The fixing structure, the positioning structure and the collimator supporting structure can all be detachably connected to the supporting structure. The connection position between the fixing structure and the supporting structure, the connection position between the positioning structure and the supporting structure, and the connection position between the collimator supporting structure and the supporting structure can be adjusted.

[0013] In some specific embodiments, the support structure includes a support column, and a position adjustment structure is provided on the support column, and the connection position between the position adjustment structure and the support column can be adjusted.

[0014] The present invention discloses a method for using the device of the positionable spatially fractionated radiotherapy collimator, comprising:

[0015] Use fixed structures to fix and mark the area to be irradiated;

[0016] Adjust the positioning structure so that the observation hole corresponds to the part to be irradiated, and mark the irradiation point of the part to be irradiated;

[0017] Place the collimator corresponding to the observation hole on the collimator supporting structure.

[0018] Compared with the prior art, the present invention has achieved the following technical effects:

[0019] The present invention uses a lead plate and a collimator that can block radiation to make the radiation range uniform and stable, and the range of radiation passing through the penetrating part is accurate and reliable. Through the cooperation of the fixed structure and the collimator bearing structure, repeated irradiation of the part to be irradiated can be achieved. By matching the position of the observation hole of the positioning structure with the position of the irradiation window, accurate positioning can be achieved, and the coverage point of the radiation passing through the collimator on the target tissue can be accurately evaluated. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0021] Figure 1 Axonometric view of a positionable spatially fractionated radiotherapy collimator in some embodiments of the present invention Figure 1 ;

[0022] Figure 2 Axonometric view of a positionable spatially fractionated radiotherapy collimator in some embodiments of the present invention Figure 2 ;

[0023] Figure 3 A front view of a positionable spatially fractionated radiotherapy collimator in some embodiments of the present invention;

[0024] Figure 4 A side view of a positionable spatially fractionated radiotherapy collimator according to some embodiments of the present invention;

[0025] Figure 5 A top view of a collimator supporting structure in some embodiments of the present invention;

[0026] Figure 6 Schematic diagram of a collimator in some embodiments of the present invention Figure 1 ;

[0027] Figure 7 Schematic diagram of a collimator in some embodiments of the present invention Figure 2 ;

[0028] Figure 8 Schematic diagram of a collimator in some embodiments of the present invention Figure 3 ;

[0029] Figure 9 Schematic diagram of a collimator in some embodiments of the present invention Figure 4 ;

[0030] Figure 10 Schematic diagram of a collimator in some embodiments of the present invention Figure 5 ;

[0031] Figure 11 Schematic diagram of a collimator in some embodiments of the present invention Figure 6 ;

[0032] Figure 12 Schematic diagram of a collimator in some embodiments of the present invention Figure 7 ;

[0033] Figure 13 Schematic diagram of a collimator in some embodiments of the present invention Figure 8 ;

[0034] Figure 14 Schematic diagram of a collimator in some embodiments of the present invention Figure 9 ;

[0035] Figure 15 A top view of the positioning structure in some embodiments of the present invention Figure 1 ;

[0036] Figure 16 A top view of the positioning structure in some embodiments of the present invention Figure 2 ;

[0037] Figure 17 A top view of a fixing structure in some embodiments of the present invention;

[0038] Figure 18 A front view of a first fixing assembly and a second fixing assembly in some embodiments of the present invention;

[0039] Figure 19 A side view of a first fixing assembly and a second fixing assembly in some embodiments of the present invention;

[0040] Figure 20 Schematic diagram of using a marking structure to mark a radiation point in some embodiments of the present invention;

[0041] In the figure: 100 - a device for a positionable spatially segmented radiotherapy collimator, 1 - a base, 2 - a fixing plate, 3 - a positioning structure, 4 - a collimator bearing structure, 5 - an observation hole, 6 - an irradiation window, 7 - a collimator, 8 - a first clamping plate, 9 - a second clamping plate, 10 - a first marking protrusion, 11 - a second marking protrusion, 12 - a screw, 13 - a knob, 14 - a nut, 15 - a support column, 16 - a position adjustment structure, 17 - a bolt, 18 - a transparent plate, 19 - a part to be irradiated, 20 - a marking structure. DETAILED DESCRIPTION

[0042] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0043] The purpose of the present invention is to provide a device and a method for using a positionable spatially segmented radiotherapy collimator to solve the problems existing in the above-mentioned prior art, so as to achieve repeated irradiation of the same part and achieve accurate positioning.

[0044] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific embodiments.

[0045] Example 1

[0046] like Figures 1 to 20 As shown, this embodiment provides a device 100 for positioning a spatially fractionated radiotherapy collimator, comprising: a base 1, a fixing structure, a positioning structure 3, and a collimator supporting structure 4 arranged from bottom to top. The fixing structure is used to clamp the part to be irradiated 19 (i.e., the target tissue, tumor). The positioning structure 3 is a transparent structure and is provided with an observation hole 5. The collimator supporting structure 4 is a lead plate and is provided with an irradiation window 6. The irradiation window 6 is used to set the collimator 7. The positions of the observation hole 5 and the irradiation window 6 correspond to each other. X-rays can irradiate the part to be irradiated 19 through the collimator 7. This embodiment uses a lead plate that can block radiation and the collimator 7 to make the radiation range uniform and stable, so that the range of radiation passing through the penetrating part is accurate and reliable, and repeated irradiation can be achieved. By matching the position of the observation hole 5 of the positioning structure 3 with the position of the irradiation window 6, accurate positioning can be achieved, and the coverage point of the radiation passing through the collimator 7 on the target tissue can be accurately evaluated.

[0047] In some specific implementations of the embodiments, the base 1 is an iron plate with a length of 200 mm, a width of 100 mm, and a height of 10 mm. The base 1 is provided with scales in both the length and width directions. The length direction is marked with a scale of 1 mm-200 mm, and the width direction is marked with a scale of 1 mm-100 mm.

[0048] In the specific implementation manner of some embodiments, the fixing structure also includes a fixing plate 2, which is arranged parallel to the base 1, and an opening is provided at the center position of the fixing plate 2, and the position of the opening corresponds to the position of the irradiation window 6; the fixing plate 2 is an iron plate with a length of 200 mm, a width of 100 mm, and a height of 10 mm, and the opening is a square through hole with a side length of 10 mm; the fixing structure also includes two oppositely arranged first fixing components and two oppositely arranged second fixing components, a first clamping plate 8 is provided at the end of the first fixing component, a first marking protrusion 10 is provided at the center position of the first clamping plate 8, and the first marking protrusion 10 is circular; the second fixing component is arranged perpendicular to the first fixing component, a second clamping plate 9 is provided at the end of the second fixing component, a second marking protrusion 11 is provided at the center position of the second clamping plate 9, and the second marking protrusion 11 is circular; the first clamping plate 8 and the second clamping plate 9 are both located at the opening, and the first clamping plate 8 and the second clamping plate 9 are both resin plates with a length of 8 mm and a width of 2 mm. During use, the biological colorimetric agent is impregnated on the first marking protrusion 10 and the second marking protrusion 11, and the side of the first clamping plate 8 provided with the first marking protrusion 10 and the side of the second clamping plate 9 provided with the second marking protrusion 11 are in contact with the part to be irradiated 19, thereby achieving the positioning and fixation of the part to be irradiated 19, and leaving a "circular" mark around the part to be irradiated 19, thereby locating the orientation of the part to be irradiated 19 on the horizontal plane, so that the range and area of ​​the fractionated radiotherapy can be accurately known in subsequent analysis and detection.

[0049] In the specific implementation manner of some embodiments, the first fixing assembly and the second fixing assembly have the same structure, and both the first fixing assembly and the second fixing assembly include a screw 12, the length of the screw 12 is 40 mm, the screw 12 passes through the through slot on the fixing plate 2, the screw 12 is threadedly connected to the nut 14 provided on the fixing plate 2, the first clamping plate 8 or the second clamping plate 9 is provided at one end of the screw 12, and a knob 13 is provided at the other end of the screw 12. The position of the first clamping plate 8 and the second clamping plate 9 can be adjusted by holding the knob 13 and rotating the screw 12 forward or backward.

[0050] In some embodiments, the positioning structure 3 is a transparent resin plate 200 mm long and 100 mm wide. The number, size, and location of the observation holes 5 correspond to those of the through holes of the collimator 7. The observation holes 5 are located below the collimator 7, at the film development area. The positioning structure 3 is provided with an observation window, which is a square through hole with a side length of 10 mm. A transmissive plate 18 is provided at the observation window. The transmissive plate 18 is detachably connected to the positioning structure 3 and has the observation holes 5 formed therein. In this embodiment, the observation holes 5 can be provided directly in the positioning structure 3 or in the transmissive plate 18.

[0051] In the specific implementation of some embodiments, a marking structure 20 is further included. The marking structure 20 is preferably an ultra-fine hollow capillary. A marking portion is provided at one end of the marking structure 20. When the position of the target tissue and the positioning structure is determined, the marking portion is dipped in biological ink, and the marking structure 20 passes through the observation hole 5. The marking portion can contact the part to be irradiated, thereby marking the irradiation point and playing a positioning role.

[0052] In some embodiments, the collimator support structure 4 is a lead plate 200 mm long, 100 mm wide, and 10 mm high. The irradiation window 6 is a square through-hole with a side length of 10 mm. The edge of the irradiation window 6 is provided with a stopper for the collimator 7, which can accommodate collimators 7 of varying micron apertures. Before each fractionated radiotherapy session, collimators 7 of varying apertures can be assembled based on the specific requirements for the irradiation aperture and channel spacing, maximizing irradiation of the target tissue.

[0053] In some embodiments, the irradiation window 6, the observation window, and the opening are all of the same size and position, and the size can be set according to the size of the tumor. The irradiation window 6 and the observation window are positioned and sized in a one-to-one correspondence to achieve precise irradiation of the target tissue during the irradiation process.

[0054] In a specific implementation manner of some embodiments, a support structure is further included, and the support structure includes support columns 15, preferably four support columns 15, and the four support columns 15 are respectively located at the four corners of the base 1, and the support columns 15 pass through the fixed plate 2, the positioning structure 3 and the collimator bearing structure 4 of the fixed structure in sequence, and the support columns 15 are vertically arranged. The base 1, the fixed plate 2, the positioning structure 3 and the collimator bearing structure 4 of the fixed structure can all be detachably connected to the support columns 15, and the connection position of the fixed plate 2 of the fixed structure and the support columns 15, the connection position of the positioning structure 3 and the support columns 15, and the connection position of the collimator bearing structure 4 and the support columns 15 can be adjusted.

[0055] In the specific implementation of some embodiments, a position adjustment structure 16 is provided on the support column 15. The position adjustment structure 16 is a sleeve, which is sleeved on the support column 15. The position of the sleeve and the support column 15 is fixed by a bolt 17 on the side of the sleeve. The connection position of the position adjustment structure 16 and the support column 15 can be adjusted.

[0056] In some embodiments, the position adjustment structure 16 can be fixedly connected to the fixed plate 2, the positioning structure 3, and the collimator support structure 4 of the fixed structure. By loosening and tightening the bolts 17, the position of the position adjustment structure 16 on the support column 15 is adjusted, thereby achieving the vertical position adjustment of the fixed plate 2, the positioning structure 3, and the collimator support structure 4 of the fixed structure. By adjusting the position of the positioning structure 3, the positioning structure 3 can be brought close to the target tissue to locate a specific irradiation point on the target tissue.

[0057] The device 100 of this embodiment, which features a positionable spatially fractionated radiotherapy collimator, can address issues with existing spatially fractionated radiotherapy devices, such as the inability to locate the specific site of high-dose irradiation, resulting in repeated irradiation of the specific high-dose site, the inability to determine the specific irradiated site during the detection phase, and the inability to perform subsequent histological analysis of the irradiated site. In this embodiment, the distance between the various structures is adjustable, and the collimator 7 is replaceable. This embodiment locates the target tissue using the positioning structure 3; only the target tissue is exposed to X-rays, enabling repeated irradiation of the target tissue; and the target tissue is secured using the fixing structure, and the target tissue position is marked, facilitating subsequent histological analysis of the irradiated site.

[0058] To address this issue, the present invention combines a replaceable collimator 7, a cross-sectional positioning plastic sheet, a horizontal plane locator, and a biological color marker. Four horizontal plane locators are used to mark the four horizontal positions of the tumor, while a cross-sectional plastic sheet aligned with the holes in the collimator 7 is used to mark the tumor's cross section. Furthermore, the modular collimator 7 enables selection of various irradiation point sizes and distances for spatially fractionated radiotherapy. The result is a spatially fractionated radiotherapy device capable of locating the tumor for radiotherapy.

[0059] Example 2

[0060] This embodiment discloses a method for using the device 100 of the first embodiment for positioning a spatially fractionated radiotherapy collimator, as follows:

[0061] First, assemble the base 1 and the fixing plate 2 of the fixed structure using four support columns 15;

[0062] Second, anesthetize the mouse using an inhalation gas anesthesia machine and wipe the entire body of the mouse with 75% alcohol to achieve the effect of disinfection; place the anesthetized mouse on the base 1, and record the placement of the mouse's head and feet according to the scales around the base 1;

[0063] 3. Adjust the position adjustment structure 16 corresponding to the fixing structure to fully expose the part to be irradiated (tumor tissue) to the opening of the fixing plate 2, so that the part to be irradiated (tumor tissue) is positioned slightly upward. Apply a biological color marker to the first marking protrusion 10 of the first clamping plate 8 and the second marking protrusion 11 of the second clamping plate 9. Gently rotate the knob 13 to ensure that the first marking protrusion 10 of the first clamping plate 8 and the second marking protrusion 11 of the second clamping plate 9 are in full contact with the part to be irradiated (tumor tissue) to achieve enhanced tissue fixation and marking of the range of the spatial radiotherapy area. When the first clamping plate 8 and the second clamping plate 9 clamp the part to be irradiated (tumor tissue), it is necessary to ensure that the first clamping plate 8 and the second clamping plate 9 are in maximum contact with the surrounding area of ​​the part to be irradiated (tumor tissue), but do not squeeze the part to be irradiated (tumor tissue) to prevent damage to the part to be irradiated (tumor tissue);

[0064] Fourth, the positioning structure 3 is fixed above the fixed structure via four support columns 15. The position adjustment structure 16 corresponding to the positioning structure 3 is adjusted so that the observation window at the center of the positioning structure 3 faces the highlighted part to be irradiated (tumor tissue) in the fixed structure. The marking portion is dipped in bio-ink, and the marking structure 20 passes through the observation hole 5. The marking portion can contact the highlighted part to be irradiated (tumor tissue), thereby marking the irradiation point. Since the observation hole 5 corresponds to the position of the irradiation window 6, the irradiation position of the part to be irradiated (tumor tissue) can be determined through the observation hole 5.

[0065] 5. Fix the collimator supporting structure 4 on the top of the positioning structure 3 through four support columns 15, and place the micron-level hole corresponding to the observation hole 5 of the positioning structure 3 on the illumination window 6 through the collimator 7;

[0066] 6. Place the device in an X-ray environment and irradiate the area to be irradiated (tumor tissue) based on the principle of spatially fractionated radiotherapy to achieve the elimination of the area to be irradiated (tumor tissue).

[0067] In the description of the present invention, it should be understood that the terms "longitudinal", "transverse", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", "third" and the like are used for descriptive purposes only and cannot be understood as indicating or implying relative importance. Thus, features defined as "first", "second", etc. may explicitly or implicitly include one or more of such features. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0068] In the description of the present invention, unless otherwise specified or limited, the terms "mounted," "connected," and "connected" should be understood in a broad sense. For example, they may refer to fixed, detachable, or integral connections; they may refer to mechanical or electrical connections; they may refer to direct connections or indirect connections through an intermediate medium; and they may refer to internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in this application.

[0069] If the present invention discloses or involves components or structural parts that are fixedly connected to each other, then, unless otherwise stated, the fixed connection can be understood as: a detachable fixed connection (for example, connection using bolts or screws), and can also be understood as: a non-detachable fixed connection (for example, riveting, welding). Of course, the mutual fixed connection can also be replaced by an integrated structure (for example, manufactured by integrated molding using a casting process) (except where it is obviously impossible to use an integrated molding process).

[0070] In addition, unless otherwise stated, the terms used in any technical solution disclosed in the present invention to express positional relationships or shapes include states or shapes that are approximate, similar, or close thereto.

[0071] Any component provided by the present invention may be assembled from multiple separate components, or may be a separate component manufactured by an integral molding process.

[0072] It should be noted that the structures, proportions, sizes, etc. depicted in the drawings of this specification are only used to match the contents disclosed in the specification so that people familiar with this technology can understand and read them. They are not used to limit the conditions under which the present invention can be implemented. Therefore, they have no substantive technical significance. Any modification of the structure, change in the proportional relationship or adjustment of the size should still fall within the scope of the technical content disclosed in the present invention without affecting the efficacy and purpose that can be achieved by the present invention.

[0073] It should also be noted that in the embodiments of the present application, the same figure mark represents the same component or the same part.

[0074] Adaptive changes based on actual needs are all within the scope of protection of the present invention.

[0075] The present invention uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only intended to help understand the method and core concept of the present invention. At the same time, those skilled in the art will find that the specific implementation methods and application scopes may vary based on the concept of the present invention. In summary, the contents of this specification should not be construed as limiting the present invention.

Claims

1. A device for positioning a spatially fractionated radiotherapy collimator, characterized by: include: The fixing structure, positioning structure and collimator supporting structure are arranged from bottom to top, the fixing structure is used to clamp the part to be irradiated, the positioning structure is a transparent structure, the positioning structure is provided with an observation hole, the collimator supporting structure is a lead plate, the collimator supporting structure is provided with an irradiation window, the irradiation window is used to set the collimator, the positions of the observation hole and the irradiation window correspond, and X-rays can be irradiated on the part to be irradiated through the collimator.

2. The device for positionable spatially fractionated radiotherapy collimator according to claim 1, characterized in that: The fixing structure includes two oppositely arranged first fixing components and two oppositely arranged second fixing components, the second fixing components are arranged perpendicular to the first fixing components, a first clamping plate is provided at the end of the first fixing component, a first marking protrusion is provided on the first clamping plate, and a second clamping plate is provided at the end of the second fixing component, and a second marking protrusion is provided on the second clamping plate.

3. The device for positionable spatially fractionated radiotherapy collimator according to claim 2, characterized in that: The fixing structure also includes a fixing plate, an opening is provided at the center position of the fixing plate, the position of the opening corresponds to the position of the irradiation window, and the first clamping plate and the second clamping plate are both located at the opening; the first fixing assembly and the second fixing assembly have the same structure, the first fixing assembly and the second fixing assembly both include a screw, the screw is threadedly connected to the fixing plate, the first clamping plate or the second clamping plate is provided at one end of the screw, and a knob is provided at the other end of the screw.

4. The device for positionable spatially fractionated radiotherapy collimator according to claim 1, characterized in that: The positioning structure is a transparent plate.

5. The device for positionable spatially fractionated radiotherapy collimator according to claim 1, characterized in that: It also includes a marking structure, one end of which is provided with a marking portion. The marking structure can pass through the observation hole, and the marking portion can contact the part to be irradiated to achieve the marking of the irradiation point; the number, size and position of the observation hole and the through hole of the collimator are set correspondingly.

6. The device for positionable spatially fractionated radiotherapy collimator according to claim 1, characterized in that: The positioning structure is provided with an observation window, and a transmission plate is provided at the observation window. The transmission plate is detachably connected to the positioning structure, and the observation hole is opened on the transmission plate.

7. The device for positionable spatially fractionated radiotherapy collimator according to claim 1, characterized in that: It also includes a base, which is located below the fixed structure and has a scale set on it.

8. The device for positionable spatially fractionated radiotherapy collimator according to claim 1, characterized in that: It also includes a supporting structure, which is vertically arranged. The fixing structure, the positioning structure and the collimator supporting structure can all be detachably connected to the supporting structure. The connection position between the fixing structure and the supporting structure, the connection position between the positioning structure and the supporting structure, and the connection position between the collimator supporting structure and the supporting structure can be adjusted.

9. The device for positionable spatially fractionated radiotherapy collimator according to claim 8, characterized in that: The support structure includes a support column, and a position adjustment structure is provided on the support column. The connection position between the position adjustment structure and the support column can be adjusted.

10. A method for using the device of any one of claims 1 to 9, characterized in that: include: Use fixed structures to fix and mark the area to be irradiated; Adjust the positioning structure so that the observation hole corresponds to the part to be irradiated, and mark the irradiation point of the part to be irradiated; Place the collimator corresponding to the observation hole on the collimator supporting structure.