Traditional Chinese medicine composition for treating ear diseases and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating ear diseases. The traditional Chinese medicine composition comprises the following components in parts by weight: 30-35 parts of prepared rehmannia roots, 20-25 parts of wine-processed fructus corni, 30-35 parts of Chinese yam slices, 15-20 parts of poria cocos, 30-35 parts of Chinese wolfberry fruits, 15-20 parts of chrysanthemums, 20-25 parts of radix pseudostellariae, 30-35 parts of astragalus membranaceus, 10-15 parts of bran-fried rhizoma atractylodis macrocephalae, 6-15 parts of bupleurum chinense, 6-10 parts of rhizoma cimicifugae, 10-15 parts of rhizoma acori graminei, 15-20 parts of fried medicated leaven and 10-15 parts of smoked plums. The traditional Chinese medicine is prepared from, by weight, 20-25 parts of fried spina date seeds, 10-15 parts of dried ginger slices, 10-15 parts of fructus amomi and 6-10 parts of licorice slices. The invention belongs to the technical field of ear disease treatment, and particularly relates to a traditional Chinese medicine composition for treating ear diseases and a preparation method thereof. The traditional Chinese medicine is used for tinnitus, deafness, tinnitus cerebri, dizziness, astringency of eyes, photophobia, dim vision, soreness of waist, weakness and the like caused by deficiency of liver-yin and kidney-yin and dysfunction of spleen in transportation.

Description

Technical Field

[0001] The present invention belongs to the technical field of ear disease treatment, and in particular relates to a traditional Chinese medicine composition for treating ear diseases and a preparation method thereof. Background Art

[0002] Tinnitus and deafness refer to the patient's perception of ringing in the ears or brain, such as the chirping of cicadas, roaring sounds, or the sound of the tide. Deafness refers to varying degrees of hearing loss, or even complete absence. Tinnitus can be accompanied by deafness, or deafness can develop from tinnitus. Although the clinical manifestations and associated symptoms of the two conditions differ, they share many similarities in their etiology and pathogenesis, both of which are closely related to the kidneys. Tinnitus and deafness can be common clinical symptoms, often seen in a variety of medical conditions across various disciplines, and can also be a separate ear disease. Because tinnitus is not an independent disease, the causes of tinnitus are complex and are still under discussion in the medical community, making it difficult to unify the classification of tinnitus.

[0003] Tinnitus can be detrimental. It affects mood: Long-term, severe tinnitus can cause feelings of irritability, worry, anxiety, anxiety, and depression. Some people would rather lose their hearing than have tinnitus, which can become unbearable. It affects work: Because it's difficult to hear others, especially those in leadership positions and teachers, and because the pain of tinnitus often makes them feel misunderstood, work efficiency declines and interest in work and school gradually diminishes. It also affects family life: Among the consequences of tinnitus, the need for long-term medical treatment and medication can lead to financial losses and even significant financial stress. Lack of understanding from family members can disrupt family harmony. It affects hearing: Extremely loud tinnitus can interfere with hearing, often causing people to hear voices but not be able to distinguish what others are saying. It affects sleep: Tinnitus is particularly loud late at night, making it difficult to fall asleep. Even when they do fall asleep, it's usually very light. Some people report being woken by tinnitus even during a shallow sleep. Waking in the middle of the night to the persistent tinnitus can cause restlessness and insomnia.

[0004] Tinnitus and deafness are associated with obstruction of the ear canals due to a variety of factors. Besides congenital hearing loss, they are often caused by acute fever, repeated colds, and the obstruction of the orifices by pathogenic heat; phlegm-fire and liver-heat, as well as physical weakness and chronic illness, which prevents qi and blood from reaching the orifices. Externally, wind-heat invades the orifices, obstructing the orifices; internally, phlegm-fire and liver-heat cause turbid qi to rise; or, due to chronic illness, liver and kidney deficiency and visceral deficiency, or spleen and stomach qi deficiency, which prevents the ascending of clear yang and prevents it from reaching the orifices. The etiology is quite complex. Chronic tinnitus and deafness, regardless of internal or external causes, are often linked to a deficiency of vital essence and qi. As stated in the "Ear Theory and Treatment" in the "Ji Sheng Fang": "Excessive fatigue initially depletes vital essence and qi, allowing wind, cold, heat, and dampness to enter from the outside; joy, anger, worry, and anxiety damage the internal organs, resulting in deafness, blindness, and tinnitus." Therefore, the depletion of vital essence and qi is one of the root causes of this condition.

[0005] Among the five internal organs, ear diseases are closely related to the spleen, kidneys, liver, and gallbladder. The kidneys are particularly closely linked. The ear is the orifice of the kidneys, receiving the twelve meridians and connecting to the brain. The brain is the sea of ​​marrow. Abundant kidney essence nourishes the marrow sea, resulting in normal hearing. Depletion of kidney essence leads to a deficiency of the marrow sea, causing tinnitus and deafness. Furthermore, the Shaoyang meridian ascends to the ear, and liver and gallbladder fire can stagnate along the meridians, easily leading to tinnitus and deafness. However, the liver is a child of the kidneys. Inflammation of liver fire, possibly due to insufficient kidney water, and internal stagnation of liver fire can easily damage kidney yin, exacerbating tinnitus and deafness. The spleen is responsible for transporting essence and promoting its function. A weak spleen prevents clear qi from ascending to the ears, resulting in turbid qi obstructing the ear orifices. Furthermore, a weak spleen impairs transport and transformation, preventing the transformation of dampness and turbidity, leading to the internal accumulation of phlegm, which generates heat and obstructs the clear orifices. Therefore, tinnitus and deafness caused by phlegm fire and dampness are often associated with spleen and stomach qi deficiency. Summary of the Invention

[0006] In view of the above situation and to overcome the shortcomings of the prior art, the present invention aims to provide a traditional Chinese medicine composition for treating ear diseases and its preparation method, which mainly nourishes the kidney and calms the liver, replenishes qi and raises yang. It is used to treat tinnitus, deafness, brain ringing, dizziness, dry eyes, photophobia, blurred vision, back pain, fatigue, etc. caused by liver and kidney yin deficiency and spleen dysfunction.

[0007] The technical solution adopted by the present invention is as follows: A traditional Chinese medicine composition for treating ear diseases comprises the following components in parts by weight: 30-35 parts of prepared rehmannia root, 20-25 parts of cornus officinalis fruit brewed with wine, 30-35 parts of yam slices, 15-20 parts of poria cocos, 30-35 parts of wolfberry fruit, 15-20 parts of chrysanthemum, 20-25 parts of pseudoginseng, 30-35 parts of astragalus, 10-15 parts of fried atractylodes macrocephala with bran, 6-15 parts of northern bupleurum, 6-10 parts of cimicifuga, 10-15 parts of calamus, 15-20 parts of fried Shaanxi six spirits, 10-15 parts of black plum, 20-25 parts of fried jujube seeds, 10-15 parts of dried ginger slices, 10-15 parts of amomum villosum, and 6-10 parts of licorice slices.

[0008] Furthermore, the present invention provides a traditional Chinese medicine composition for treating ear diseases, comprising the following components in parts by weight: 32-33 parts of Rehmannia root, 22-23 parts of cornus officinalis, 32-33 parts of yam slices, 17-18 parts of Poria cocos, 32-33 parts of wolfberry, 17-18 parts of chrysanthemum, 22-23 parts of Pseudostellaria pseudoginseng, 32-33 parts of Astragalus membranaceus, 12-13 parts of stir-fried Atractylodes macrocephala with bran, 10-11 parts of Bupleurum chinense, 7-9 parts of Cimicifuga heracleifolia, 12-13 parts of Acorus calamus, 17-18 parts of stir-fried Shaanxi Six-spirit Qu, 12-13 parts of black plum, 22-23 parts of stir-fried Ziziphus jujuba seeds, 12-13 parts of dried ginger slices, 12-13 parts of Amomum villosum, and 7-9 parts of licorice slices.

[0009] Furthermore, the present invention provides a traditional Chinese medicine composition for treating ear diseases, comprising the following components in parts by weight: 32.5 parts of Rehmannia root, 22.5 parts of wine-soaked Cornus officinalis, 32.5 parts of Chinese yam slices, 17.5 parts of Poria cocos, 32.5 parts of Lycium barbarum, 17.5 parts of Chrysanthemum, 22.5 parts of Pseudostellaria pseudoginseng, 32.5 parts of Astragalus, 12.5 parts of fried Atractylodes macrocephala with bran, 10.5 parts of Bupleurum chinense, 8 parts of Cimicifuga heracleifolia, 12.5 parts of Acorus calamus, 17.5 parts of fried Shaanxi Six-spirit Qu, 12.5 parts of black plums, 22.5 parts of fried Ziziphus jujuba seeds, 12.5 parts of dried ginger slices, 12.5 parts of Amomum villosum, and 8 parts of liquorice tablets.

[0010] Furthermore, the present invention provides a method for preparing a traditional Chinese medicine composition for treating ear diseases, comprising the following steps:

[0011] Step 1:

[0012] Grind eleven medicinal materials including yam slices, poria cocos, chrysanthemum, pseudoginseng, bran-fried atractylodes macrocephala, cimicifuga heracleifolia, calamus, fried Shaanxi six-spirit malt, fried spinach seeds, dried ginger slices, and amomum villosum into fine powder;

[0013] Step 2:

[0014] Mix the seven herbs: Rehmannia root, cornus officinalis, wolfberry fruit, astragalus root, bupleurum root, black plum, and liquorice slices, add 8 times the amount of water and boil three times, each time for 2 hours;

[0015] Step 3:

[0016] Filter the decoction each time and combine the filtered liquid into the filtrate;

[0017] Step 4:

[0018] The filtrate is concentrated to an extract with a relative density of 1.25-1.30. This step is carried out at a temperature of 60°C-65°C.

[0019] Step 5:

[0020] Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly;

[0021] Step 6:

[0022] Making pellets from the fine powder mixed after pulverization in step 4;

[0023] Step 7:

[0024] The pellets were dried at 60°C.

[0025] After adopting the above technical scheme, the beneficial effects of the present invention are as follows: a traditional Chinese medicine composition for treating ear diseases and a preparation method thereof are provided, which is suitable for patients with tinnitus, deafness and the like who meet the above-mentioned traditional Chinese medicine symptoms. The present application is composed of 18 traditional Chinese medicines including Rehmannia root, wine-soaked Cornus officinalis, Chinese yam slices, Poria cocos, Lycium barbarum, chrysanthemum, Pseudostellaria baicalensis, Astragalus membranaceus, stir-fried Atractylodes macrocephala with bran, Bupleurum chinense, Cimicifuga heracleifolia, Acorus gramineus, stir-fried Shaanxi Six-spirited Qu, Prunus mume, stir-fried Ziziphus jujuba seeds, dried ginger slices, Amomum villosum, and licorice slices. Among them, Rehmannia root is sweet, nourishing and slightly warming, good at nourishing yin and blood, benefiting the kidney and replenishing essence, and is an important medicine for nourishing the liver and kidney and benefiting essence and blood. Astragalus membranaceus is sweet and slightly warming, can induce sleep in the lung meridian, replenish the middle and benefit qi, and raise yang and consolidate the exterior, so they are both monarch medicines. Cornus officinalis is sour, sweet, slightly warm, and astringent, effectively nourishing the liver and kidneys. Chinese yam is sweet, astringent, and neutral, effectively nourishing yin and tonifying qi, tonifying the spleen, lungs, and kidneys, making it a key herb for balancing qi and yin. Lycium barbarum is sweet, moist, and neutral, effectively nourishing the liver and kidneys, improving essence and vision. Chrysanthemum is sweet, bitter, and slightly cold, effectively dispelling wind and clearing heat, calming the liver, and improving eyesight. These four herbs combined not only assist the main herb in nourishing the kidneys and liver, but also dispel wind, purging fire, and improving eyesight. Pseudostellaria chinensis, licorice, and stir-fried Atractylodes macrocephala are assistant herbs, tonifying qi and strengthening the spleen. Poria cocos is sweet, tonic, mild, and penetrating, effectively strengthening the spleen, dispelling dampness, and combining it with Amomum villosum to dissipate dampness and stimulate the appetite, warming the spleen and regulating qi. Chinese yam strengthens the spleen and kidneys without retaining dampness. Combined with stir-fried Shenqu (Shenqu), it helps digest food, resolves accumulation, strengthens the spleen and harmonizes the stomach. Black plums promote fluid production and benefit the stomach, while dried ginger warms the middle and dispels cold, warming the lungs and eliminating dampness. Small amounts of Cimicifuga heracleifolia and Bupleurum chinense raise yang and lift sunken qi, assisting the main herb in activating and lifting sunken qi. Licorice harmonizes the other herbs and serves as an adjuvant. Ziziphus jujuba seeds nourish the heart and calm the mind. Acorus calamus: Its pungent flavor and warm nature enter the Heart and Stomach meridians. Its aromatic properties eliminate dampness, dissipate phlegm and reduce oiliness, brighten the eyes and ears, and open the nine orifices. Acorus calamus is a sacred medicine for opening the ears, clearing phlegm, opening the orifices, and promoting heart qi. Its fragrance can invigorate the spirit, its pungent properties can control wind, its warmth can unblock the meridians, and its bitterness can dry dampness and resolve phlegm. Its pungent and bitter properties can act both upward and downward, making it effective in treating tinnitus, deafness, and shortness of breath. Furthermore, its pill formulation is more convenient for patients, expanding the medication population and thus improving patient compliance. DETAILED DESCRIPTION

[0026] The technical solutions in the embodiments of the present invention are clearly and completely described below. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0027] Example 1:

[0028] The invention discloses a traditional Chinese medicine composition for treating ear diseases. The composition comprises the following components in parts by weight: 30 parts of prepared rehmannia root, 20 parts of cornus officinalis fruit cooked with wine, 30 parts of yam slices, 15 parts of poria cocos, 30 parts of wolfberry fruit, 15 parts of chrysanthemum, 20 parts of pseudoginseng, 30 parts of astragalus, 10 parts of fried atractylodes macrocephala with bran, 6 parts of northern bupleurum, 6 parts of cimicifuga heracleifolia, 10 parts of calamus, 15 parts of fried Shaanxi six spirit qu, 10 parts of black plum, 20 parts of fried jujube seeds, 10 parts of dried ginger slices, 10 parts of amomum villosum, and 6 parts of liquorice slices.

[0029] The present invention provides a method for preparing a traditional Chinese medicine composition for treating ear diseases, comprising the following steps:

[0030] Step 1:

[0031] Grind eleven medicinal materials including yam slices, poria cocos, chrysanthemum, pseudoginseng, bran-fried atractylodes macrocephala, cimicifuga heracleifolia, calamus, fried Shaanxi six-spirit malt, fried spinach seeds, dried ginger slices, and amomum villosum into fine powder;

[0032] Step 2:

[0033] Mix the seven herbs: Rehmannia root, cornus officinalis, wolfberry fruit, astragalus root, bupleurum root, black plum, and liquorice slices, add 8 times the amount of water and boil three times, each time for 2 hours;

[0034] Step 3:

[0035] Filter the decoction each time and combine the filtered liquid into the filtrate;

[0036] Step 4:

[0037] The filtrate is concentrated to an extract with a relative density of 1.25-1.30. This step is carried out at a temperature of 60°C-65°C.

[0038] Step 5:

[0039] Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly;

[0040] Step 6:

[0041] Making pellets from the fine powder mixed after pulverization in step 4;

[0042] Step 7:

[0043] The pellets were dried at 60°C.

[0044] Example 2:

[0045] The invention discloses a traditional Chinese medicine composition for treating ear diseases. The composition comprises the following components in parts by weight: 32.5 parts of prepared rehmannia root, 22.5 parts of cornus officinalis fruit, 32.5 parts of yam slices, 17.5 parts of tuckahoe, 32.5 parts of wolfberry fruit, 17.5 parts of chrysanthemum, 22.5 parts of pseudoginseng, 32.5 parts of astragalus, 12.5 parts of fried atractylodes macrocephala with bran, 10.5 parts of northern bupleurum, 8 parts of cimicifuga, 12.5 parts of calamus, 17.5 parts of fried Shaanxi six spirit qu, 12.5 parts of black plum, 22.5 parts of fried jujube seeds, 12.5 parts of dried ginger slices, 12.5 parts of amomum villosum, and 8 parts of liquorice slices.

[0046] The present invention provides a method for preparing a traditional Chinese medicine composition for treating ear diseases, comprising the following steps:

[0047] Step 1:

[0048] Grind eleven medicinal materials including yam slices, poria cocos, chrysanthemum, pseudoginseng, bran-fried atractylodes macrocephala, cimicifuga heracleifolia, calamus, fried Shaanxi six-spirit malt, fried spinach seeds, dried ginger slices, and amomum villosum into fine powder;

[0049] Step 2:

[0050] Mix the seven herbs: Rehmannia root, cornus officinalis, wolfberry fruit, astragalus root, bupleurum root, black plum, and liquorice slices, add 8 times the amount of water and boil three times, each time for 2 hours;

[0051] Step 3:

[0052] Filter the decoction each time and combine the filtered liquid into the filtrate;

[0053] Step 4:

[0054] The filtrate is concentrated to an extract with a relative density of 1.25-1.30. This step is carried out at a temperature of 60°C-65°C.

[0055] Step 5:

[0056] Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly;

[0057] Step 6:

[0058] Making pellets from the fine powder mixed after pulverization in step 4;

[0059] Step 7:

[0060] The pellets were dried at 60°C.

[0061] Example 3:

[0062] The invention discloses a traditional Chinese medicine composition for treating ear diseases. The composition comprises the following components in parts by weight: 35 parts of prepared rehmannia root, 25 parts of cornus officinalis fruit cooked with wine, 35 parts of yam slices, 20 parts of tuckahoe, 35 parts of wolfberry fruit, 20 parts of chrysanthemum, 25 parts of pseudoginseng, 35 parts of astragalus, 15 parts of fried atractylodes macrocephala with bran, 15 parts of northern bupleurum, 10 parts of cimicifuga, 15 parts of calamus, 20 parts of fried Shaanxi six spirit qu, 15 parts of black plum, 25 parts of fried jujube seeds, 15 parts of dried ginger slices, 15 parts of amomum villosum, and 10 parts of liquorice slices.

[0063] The present invention provides a method for preparing a traditional Chinese medicine composition for treating ear diseases, comprising the following steps:

[0064] Step 1:

[0065] Grind eleven medicinal materials including yam slices, poria cocos, chrysanthemum, pseudoginseng, bran-fried atractylodes macrocephala, cimicifuga heracleifolia, calamus, fried Shaanxi six-spirit malt, fried spinach seeds, dried ginger slices, and amomum villosum into fine powder;

[0066] Step 2:

[0067] Mix the seven herbs: Rehmannia root, cornus officinalis, wolfberry fruit, astragalus root, bupleurum root, black plum, and liquorice slices, add 8 times the amount of water and boil three times, each time for 2 hours;

[0068] Step 3:

[0069] Filter the decoction each time and combine the filtered liquid into the filtrate;

[0070] Step 4:

[0071] The filtrate is concentrated to an extract with a relative density of 1.25-1.30. This step is carried out at a temperature of 60°C-65°C.

[0072] Step 5:

[0073] Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly;

[0074] Step 6:

[0075] Making pellets from the fine powder mixed after pulverization in step 4;

[0076] Step 7:

[0077] The pellets were dried at 60°C.

[0078] The above description of the present invention and its embodiments is non-limiting, and the actual structure is not limited thereto. In short, if a person skilled in the art is inspired by the above description and, without departing from the purpose of the present invention, designs a structure and embodiment similar to the technical solution without creatively designing, they shall fall within the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for treating ear diseases, characterized in that: The invention comprises the following components in parts by weight: 30-35 parts of prepared rehmannia root, 20-25 parts of cornus officinalis fruit, 30-35 parts of yam slices, 15-20 parts of poria cocos, 30-35 parts of wolfberry fruit, 15-20 parts of chrysanthemum, 20-25 parts of pseudoginseng, 30-35 parts of astragalus, 10-15 parts of fried atractylodes macrocephala with bran, 6-15 parts of northern bupleurum, 6-10 parts of cimicifuga, 10-15 parts of calamus, 15-20 parts of fried Shaanxi six spirit qu, 10-15 parts of black plum, 20-25 parts of fried jujube seeds, 10-15 parts of dried ginger slices, 10-15 parts of amomum villosum, and 6-10 parts of licorice slices.

2. The Chinese medicine composition for treating ear diseases according to claim 1, characterized in that The invention comprises the following components in parts by weight: 32-33 parts of prepared rehmannia root, 22-23 parts of cornus officinalis fruit, 32-33 parts of yam slices, 17-18 parts of poria cocos, 32-33 parts of wolfberry fruit, 17-18 parts of chrysanthemum, 22-23 parts of pseudoginseng, 32-33 parts of astragalus, 12-13 parts of fried atractylodes macrocephala with bran, 10-11 parts of northern bupleurum, 7-9 parts of cimicifuga, 12-13 parts of calamus, 17-18 parts of fried Shaanxi six spirit qu, 12-13 parts of black plum, 22-23 parts of fried jujube seeds, 12-13 parts of dried ginger slices, 12-13 parts of amomum villosum, and 7-9 parts of licorice slices.

3. The Chinese medicine composition for treating ear diseases according to claim 1, characterized in that The invention comprises the following components in parts by weight: 32.5 parts of prepared rehmannia root, 22.5 parts of cornus officinalis fruit, 32.5 parts of yam slices, 17.5 parts of poria cocos, 32.5 parts of wolfberry fruit, 17.5 parts of chrysanthemum, 22.5 parts of pseudoginseng, 32.5 parts of astragalus, 12.5 parts of fried atractylodes macrocephala with bran, 10.5 parts of northern bupleurum, 8 parts of cimicifuga, 12.5 parts of calamus, 17.5 parts of fried Shaanxi six spirit qu, 12.5 parts of black plum, 22.5 parts of fried jujube seeds, 12.5 parts of dried ginger slices, 12.5 parts of amomum villosum, and 8 parts of licorice slices.

4. A method for preparing the traditional Chinese medicine composition for treating ear diseases according to any one of claims 1 to 3, characterized in that: The following steps are involved: Step 1: Grind eleven medicinal materials including yam slices, poria cocos, chrysanthemum, pseudoginseng, bran-fried atractylodes macrocephala, cimicifuga heracleifolia, calamus, fried Shaanxi six-spirit malt, fried spinach seeds, dried ginger slices, and amomum villosum into fine powder; Step 2: Mix the seven herbs: Rehmannia root, cornus officinalis, wolfberry fruit, astragalus root, bupleurum root, black plum, and liquorice slices, add 8 times the amount of water and boil three times, each time for 2 hours; Step 3: Filter the decoction each time and combine the filtered liquid into the filtrate; Step 4: The filtrate is concentrated to an extract with a relative density of 1.25-1.

30. This step is carried out at a temperature of 60°C-65°C. Step 5: Mix the fine powder and extract evenly, dry them to 60℃, grind them into fine powder and mix them evenly; Step 6: Making pellets from the fine powder mixed after pulverization in step 4; Step 7: The pellets were dried at 60°C.