An arc-shaped operating instrument for deep brain surgery in animals
By designing an arc-shaped operating instrument that combines rectangular and polar coordinate systems, the problem of inaccurate positioning in deep brain surgery in animals has been solved. This achieves efficient and precise three-dimensional positioning, making it suitable for brain surgery in large animals such as macaques and improving the versatility and adaptability of the equipment.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- LIANGZHU LAB
- Filing Date
- 2025-07-22
- Publication Date
- 2026-05-19
AI Technical Summary
Existing instruments are insufficient for precise localization in deep brain surgery in animals, especially large animals such as macaques. Furthermore, they cannot directly convert rectangular coordinates to polar coordinates, which is complex and time-consuming, affecting experimental efficiency and animal condition.
An arc-shaped manipulator combining rectangular and polar coordinate systems was designed, including an arc arm assembly and a calibration platform. The zero point of the device is directly calibrated to the zero point of the stereo positioning instrument through multiple adjustable joints, supporting rapid replacement of experimental equipment, realizing flexible interchange between vertical and polar coordinates, and possessing three-dimensional positioning capabilities.
It achieves high-precision and rapid positioning of the equipment in deep brain surgery in animals, reduces computational work, improves the versatility and adaptability of the equipment, meets the needs of complex three-dimensional anatomical paths, and is suitable for brain surgery in non-human primates.
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Figure CN120814926B_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the technical field of animal intracranial surgical positioning tools, specifically relating to an arc-shaped operating instrument for deep brain surgery in animals. Background Technology
[0002] In recent years, the demand for research on deep nuclei (such as the thalamus and basal ganglia) in basic neuroscience has been increasing. Because these nuclei are located deep in the brain, precise localization is required to meet the needs of subsequent operations on the target nuclei, such as electrophysiological recording, electrical stimulation, or viral injection.
[0003] Most instruments on the market currently use a Cartesian coordinate system for localization and construct brain maps of different species within this framework. However, the brain is approximately spherical, and when performing procedures such as electrical stimulation on certain deep nuclei, vertical localization methods make it difficult to ensure that electrodes effectively avoid blood vessels within the brain. Although some instruments on the market also offer rotation capabilities, they suffer from several drawbacks: firstly, these instruments require subsequent coordinate conversion from Cartesian to polar coordinates to obtain usable data, which is complex and time-consuming, making it difficult to handle unexpected situations, and prolonged anesthesia can negatively impact the animal's condition; secondly, these instruments have limited adjustment freedom, making it difficult to cover the entire brain and resulting in inaccurate localization.
[0004] Existing curved manipulators are designed specifically for the human brain based on polar coordinates and are only used in clinical brain surgery. They cannot be adapted to the cranium of large animals (such as macaques). In addition, these curved manipulators cannot directly convert the rectangular coordinates of animal atlases into polar coordinates, making them unusable in basic scientific research. Their application scenarios are relatively limited, and they cannot provide supporting clamping devices for operations such as electrophysiological recording or virus injection in basic scientific research.
[0005] Therefore, it is necessary to design an instrument that combines rectangular and polar coordinate systems and is suitable for deep brain surgery in animals (excluding humans). Summary of the Invention
[0006] To address the aforementioned problems in existing technologies, this solution provides an arc-shaped manipulation instrument for deep brain surgery in animals.
[0007] The technical solution adopted in this invention is as follows:
[0008] An arc-shaped operating instrument for deep brain surgery in animals, including an arc arm assembly and a calibration table;
[0009] The calibration platform includes an X-axis calibration block, a Y-axis calibration block, a Z-axis calibration block, and a calibration axis seat. The X-axis calibration block is connected to the X-axis slide of the stereo positioning instrument and can be adjusted in the X-axis direction. The Y-axis calibration block is connected to the X-axis calibration block and can be adjusted in the Y-axis direction. The Z-axis calibration block is connected to the Y-axis calibration block and can be adjusted in the Z-axis direction. The calibration axis seat is fixed on the Z-axis calibration block. After the calibration platform is installed, the axis of the calibration axis is parallel to the Y-axis and passes through the zero point of the stereo positioning instrument. The X, Y, and Z axes are perpendicular to each other.
[0010] The arc arm assembly includes an arc-shaped ruler, a clamp assembly, and a radial adjuster. One end of the arc-shaped ruler is connected to a calibration shaft seat and can rotate about the axis of the calibration shaft. The center of the arc of the arc-shaped ruler coincides with the zero point of the stereo positioning instrument. A slidable arc rail slider is provided on the arc-shaped ruler. The radial adjuster is mounted on the arc rail slider and slides along the arc-shaped ruler. The clamp assembly is mounted on the radial adjuster and is adjusted by it to position itself radially on the arc-shaped ruler. Surgical tools or adjustment pointers can be mounted on the clamp assembly, and the axes of the surgical tools and adjustment pointers coincide with the radial direction of the arc-shaped ruler.
[0011] As an alternative or supplement to the above structure: the X-axis calibration block is L-shaped, and an X-axis adjustment knob is provided on the X-axis calibration block. The screw connected to the X-axis adjustment knob is threadedly connected to the X-axis slide.
[0012] As an alternative or supplement to the above structure: the end of the Y-axis calibration block connected to the X-axis calibration block has a connection hole parallel to the Y-axis, and the end of the Z-axis calibration block connected to the Y-axis calibration block has a connection hole parallel to the Z-axis.
[0013] As an alternative or supplement to the above structure: the stereo positioning instrument is provided with a movable positioning lug, the positioning lug is parallel to the Y direction, the movement trajectory of the positioning lug is parallel to the Y direction, and the axis of the positioning lug passes through the zero point of the stereo positioning instrument; the Z-axis calibration block is provided with a calibration hole, the calibration hole is coaxial with the calibration shaft seat, and when the positioning lug is inserted into the calibration hole, the calibration shaft seat is coaxial with it.
[0014] As an alternative or supplement to the above structure: the radial adjuster includes an adjustment platform, a radial adjustment knob, a threaded rod, a radial slide, and a guide rod; the threaded rod and the guide rod are parallel to the radial direction of the arc ruler; the threaded rod is connected to the radial adjustment knob and rotatably connected to the adjustment platform; the radial slide is slidably engaged with the guide rod and threadedly engaged with the threaded rod; the adjustment platform is detachably connected to the slider fixed on the arc rail.
[0015] As an alternative or supplement to the above structure: the clamp assembly includes an upper clamping arm, a radial seat rod, a lower clamping arm, and a chuck; the upper end of the radial seat rod is connected to the radial slide via the upper clamping arm, one end of the lower clamping arm straightens the middle of the radial seat rod, and the other end is connected to the adjustment table; the chuck is connected to the lower end of the radial seat rod, and the clamping jaws of the chuck are used to install surgical tools or adjust pointers.
[0016] As an alternative or supplement to the above structure: the upper and lower clamping arms are provided with elongated holes, and a clamp is connected to the elongated holes, the clamp being used to connect the radial seat rod.
[0017] As an alternative or supplement to the above structure: an adjusting chuck is fixedly connected to the end of the arc-shaped ruler, the adjusting chuck is sleeved on the calibration shaft seat, and a clamping screw for adjusting the clamping force is provided on the adjusting chuck.
[0018] As an alternative or supplement to the above structure: a limiter is installed at the other end of the arc-shaped ruler, which is used to limit the sliding range of the surgical instruments and the adjustment pointer.
[0019] The beneficial effects of this invention are as follows:
[0020] 1. The structure of this solution is designed with a large number of adjustable joints, combining the rectangular coordinate system and the polar coordinate system. By adjusting, the zero point of this device can be directly calibrated to the position that coincides with the zero point of the stereo positioning instrument, without the need for subsequent conversion, reducing subsequent calculation work, enabling real-time response during surgery, and realizing flexible conversion between vertical coordinates and polar coordinates.
[0021] 2. The structure of this solution adopts a modular design, which supports quick replacement and is compatible with the installation of various experimental equipment (such as electrophysiological electrodes, injection needles, etc.), improving the versatility and adaptability of the equipment and increasing the application scenarios; when the adjustment knobs are replaced with stepper motors, electric control can also be achieved to meet different experimental needs.
[0022] 3. The structure of this solution breaks through the limitations of traditional two-dimensional positioning and can meet the needs of complex three-dimensional anatomical paths; it provides fine-tuning capabilities in horizontal, vertical and rotational directions, and can accurately locate multiple deep areas within the whole brain at complex angles; through precise adjustment of structures such as dials, lead screws and sliders, high-precision positioning can be achieved, ensuring the stability of the equipment in complex operations.
[0023] 4. The structure of this solution is optimized for the needs of brain surgery in non-human primates (such as macaques), and the size and structure of the equipment are optimized, filling the gap in the field of basic brain science research. The equipment simplifies the operation process through the visual design of the dial, slider and lead screw, enabling experimental personnel to quickly and intuitively complete positioning and adjustment tasks. Attached Figure Description
[0024] To more clearly illustrate the technical solutions in the embodiments of this scheme or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below.
[0025] Figure 1 This is a schematic diagram of the arc-shaped operating device in this scheme;
[0026] Figure 2 This is another perspective structural diagram of the arc-shaped operating device in this scheme;
[0027] Figure 3 This is a schematic diagram of the structure of a stereo positioning device;
[0028] Figure 4 This is a schematic diagram of the calibration platform;
[0029] Figure 5 It is a structural diagram of the mating structure between the arc-shaped ruler and the calibration platform;
[0030] Figure 6 This is a diagram showing the assembly structure of the radial adjuster and the clamp assembly.
[0031] In the diagram: 1-Stereopositioner; 11-X-axis rail; 12-Positioning lug; 13-Fixed seat; 14-X-axis slide; 2-Arc ruler; 3-Arc rail slider; 4-Radial adjuster; 41-Adjusting platform; 42-Radial adjustment knob; 43-Threaded rod; 44-Radial slide; 45-Guide rod; 5-Adjustment pointer; 6-Calibration platform; 61-X-axis calibration block; 62-X-axis adjustment knob; 63-Y-axis calibration block; 64-Z-axis calibration block; 641-Calibration hole; 65-Calibration shaft seat; 7-Adjusting chuck; 71-Clamping screw; 8-Clamping assembly; 81-Upper clamp arm; 82-Radial seat rod; 83-Lower clamp arm; 84-Chuck. Detailed Implementation
[0032] The technical solutions in this embodiment will be clearly and completely described below with reference to the accompanying drawings. The described embodiments are only a part of the embodiments, not all of them. All other embodiments obtained by those skilled in the art based on the embodiments in this solution without creative effort are within the protection scope of this solution.
[0033] like Figures 1 to 6 As shown, this design presents an arc-shaped operating instrument for deep brain surgery in animals, comprising an arc arm assembly and a calibration platform 6. The calibration platform 6 is mounted on a stereotactic instrument 1, and the arc arm assembly is mounted on the calibration platform 6.
[0034] The stereoscopic positioning device 1 includes components such as an X-axis rail 11, positioning lugs 12, a fixed base 13, and an X-axis slide 14. The X-axis rail 11 comprises two parallel rails, with their length direction parallel to the X-axis. One end of each rail 11 is fixedly connected by the fixed base 13. In use, the fixed base 13 is fixed to an operating table or laboratory table. A positioning lug 12 is located on the lower side of the middle of each X-axis rail 11, with the two lugs 12 aligned on the same straight line. The midpoint between the two lugs coincides with the zero point of the stereoscopic positioning device 1. The positioning lugs 12 are parallel to the Y-axis, and their movement trajectory is parallel to the Y-axis. The axis of the positioning lugs 12 passes through the zero point of the stereoscopic positioning device 1. The X-axis slide 14 is slidably mounted on the X-axis rail 11. When the X-axis slide 14 slides back and forth along the X-axis, it can adjust the position of the arc arm assembly and the calibration platform 6 in the forward and backward direction.
[0035] The calibration platform 6 includes components such as an X-axis calibration block 61, a Y-axis calibration block 63, a Z-axis calibration block 64, and a calibration bearing 65. The X, Y, and Z axes are perpendicular to each other.
[0036] The X-axis calibration block 61 is connected to the X-axis slide 14 of the stereo positioning device 1 and can be adjusted in the X-axis direction. The X-axis calibration block 61 is L-shaped and has an X-axis adjustment knob 62. The screw connected to the X-axis adjustment knob 62 is threadedly connected to the X-axis slide 14. After the X-axis slide 14 has slid back and forth to its approximate position and is fixed by a pin, the X-axis adjustment knob 62 can be rotated to finely adjust the position of the X-axis calibration block 61.
[0037] The Y-axis calibration block 63 is connected to the X-axis calibration block 61 and can be adjusted in the Y-axis position. One end of the Y-axis calibration block 63 has a connecting hole (elongated hole) parallel to the Y-axis. By adjusting the connection position of the screw in the connecting hole, the Y-axis calibration block 63 can be precisely adjusted in the Y-axis direction. A Y-axis scale area can be set on the side surface of the Y-axis calibration block 63 to facilitate viewing and recording the adjustment position of the Y-axis calibration block 63 in the Y-axis direction.
[0038] The Z-axis calibration block 64 is connected to the Y-axis calibration block 63 and can be adjusted in the Z-axis position. The upper end of the Z-axis calibration block 64 has a connecting hole (elongated hole) parallel to the Z-axis. By adjusting the connection position of the screw in the connecting hole, the precise position adjustment of the Z-axis calibration block 64 in the Z-axis direction can be achieved. A calibration hole 641 is provided on the side surface of the Z-axis calibration block 64. The calibration hole 641 is coaxial with the calibration shaft seat 65. When the positioning lug 12 is inserted into the calibration hole 641, it can quickly ensure that the calibration shaft seat 65 and the positioning lug 12 are coaxial.
[0039] The calibration shaft seat 65 is fixed on the Z-axis calibration block 64. After the calibration platform 6 is installed, the axis of the calibration shaft is parallel to the Y-axis and passes through the zero point of the stereo positioning instrument 1; the end of the calibration shaft seat 65 is cylindrical.
[0040] The arc arm assembly includes an arc ruler 2, a clamp assembly 8, and a radial adjuster 4.
[0041] One end of the arc-shaped ruler 2 is connected to the calibration shaft seat 65 via an adjusting chuck 7, allowing the arc-shaped ruler 2 to rotate about the axis of the calibration shaft. The adjusting chuck 7 is fixedly connected to the end of the arc-shaped ruler 2 and is fitted onto the calibration shaft seat 65. A clamping screw 71 for adjusting the clamping force is provided on the adjusting chuck 7. A circular scale is provided at one end of the adjusting chuck 7, and the scale on the scale displays the distance the arc-shaped ruler 2 has rotated. The center of the arc of the arc-shaped ruler 2 coincides with the zero point of the stereoscopic positioning instrument 1. A sliding arc-shaped slider 3 is provided on the arc-shaped ruler 2; when the arc-shaped slider 3 slides to different positions, the scale data at that position can be read. Furthermore, a limiter is installed at the other end of the arc-shaped ruler 2 to limit the sliding range of the surgical instruments and the calibration pointer 5.
[0042] A radial adjuster 4 is mounted on the arc-shaped slider 3. The radial adjuster 4 slides along the arc-shaped ruler 2 with the arc-shaped slider 3 and has graduations on the arc-shaped ruler 2. The radial adjuster 4 includes an adjustment platform 41, a radial adjustment knob 42, a threaded rod 43, a radial slide 44, and a guide rod 45. The threaded rod 43 and the guide rod 45 are parallel to the radial direction of the arc-shaped ruler 2. The threaded rod 43 is connected to the radial adjustment knob 42 and rotatably connected to the adjustment platform 41. The radial slide 44 is slidably engaged with the guide rod 45 and threadedly engaged with the threaded rod 43. The adjustment platform 41 is detachably connected to the arc-shaped slider 3.
[0043] The clamp assembly 8 is mounted on the radial adjuster 4 and is adjusted by it to position itself radially on the arc-shaped ruler 2. Surgical tools or adjustment pointers 5 can be mounted on the clamp assembly 8, with the axes of the surgical tools and adjustment pointers 5 coinciding radially with the arc-shaped ruler 2. The clamp assembly 8 includes an upper clamping arm 81, a radial seat rod 82, a lower clamping arm 83, and a clamp head 84. The upper end of the radial seat rod 82 is connected to the radial slide table 44 via the upper clamping arm 81. One end of the lower clamping arm 83 straightens the middle of the radial seat rod 82, and the other end is connected to the adjustment table 41. The clamp head 84 is connected to the lower end of the radial seat rod 82, and its jaws are used to mount surgical tools or adjustment pointers 5.
[0044] The upper clamping arm 81 and the lower clamping arm 83 are provided with elongated holes, and a clamp is connected to the elongated holes. The clamp is used to connect the radial seat rod 82. When the clamp is connected to different positions of the upper clamping arm 81 and the lower clamping arm 83, the axial deviation of the radial seat rod 82 can be adjusted, thereby ensuring that the axis of the radial seat rod 82 is parallel to the radial direction of the arc ruler 2.
[0045] The working process of the arc-shaped operating device in this scheme is as follows:
[0046] (1) Zero point calibration of equipment: First, fix the stereo positioning instrument 1, assemble the arc-shaped operating instrument and install it on the X-axis slide 14 of the stereo positioning instrument 1 with zero point, and install the calibration pointer 5 on the clamp assembly 8. Slide the X-axis slide 14 back and forth until the calibration pointer 5 roughly points to the zero point on the stereoscopic locator 1. Rotate the radial adjustment knob 42 to lower the height of the calibration pointer 5, bringing it as close to the zero point as possible. At this time, loosen the X-axis calibration block 61, Y-axis calibration block 63, and Z-axis calibration block 64 to fine-tune the calibration pointer 5 in the horizontal, back-and-forth, and vertical directions. Simultaneously, fine-tune the rotation angle of the arc ruler 2 as needed, aligning the 0° line of the scale with the pointing line on its right side, ensuring that the calibration pointer 5 is completely perpendicular to the zero point on the stereoscopic locator 1. At this point, the entire arc ruler 2 is considered to have completed zero-point calibration. Record the scale readings of each component at this time, which are the "zero points" of all scales on the operating arm. Based on this, the calibration pointer 5 is considered to be completely at the "zero point" in the animal brain atlas coordinate system. After zeroing, raise the calibration pointer 5 to a safe height and tighten all screws to prevent accidents and prepare for subsequent use.
[0047] (2) After the macaque is induced to be anesthetized, its head is fixed on the stereotactic device 1. Two ear rods are inserted into the left and right ear canals of the macaque, respectively. The positions of the ear rods are adjusted so that the macaque's head is fixed in the middle of the stereotactic device 1 as much as possible.
[0048] (3) After disinfecting the macaque’s head skin, the head skin is cut open with a scalpel, and the muscles and periosteum are removed to fully expose the skull. The position of the animal’s head is then slightly adjusted left and right according to the midline of the skull surface so that the midline of the animal’s skull is as completely as possible on the central axis of the stereo positioning instrument 1. The midline of the skull and the ear rod lines on the left and right sides are drawn on the surface of the animal’s skull with a marker. The intersection of the two lines on the skull can be considered as the projection of the coordinate zero point in the brain atlas onto the skull.
[0049] (4) Remove the entire manipulator arm, along with the X-axis slide 14 on the stereo locator 1, from the zeroed stereo locator 1 and install it on the animal's stereo locator 1. Move the slider of the stereo locator 1 to the "zero point position" after zero-point calibration. First, observe whether the height of the calibration axis seat 65 is level with the ear rod. If it is not on the same horizontal line, the arc ruler 2 will not be pointing completely to the "zero point position" in the brain map coordinates. Then, lower the height of the calibration pointer 5 so that it is as close as possible to the surface of the animal's skull. Observe whether the calibration pointer 5 is pointing vertically to the intersection on the skull. If not, prioritize fine-tuning the position of the animal's head on the stereo locator 1. If it is impossible to completely match the calibration pointer 5 by adjusting the animal's head due to factors such as excessive differences in the animal's head, consider fine-tuning the part on the manipulator arm so that the calibration pointer 5 is pointing completely vertically to the intersection on the skull. Record the scale at this time and mark it as the new "zero point position". Subsequent movements and other operations are calculated based on this "zero point position".
[0050] (5) Based on the three-dimensional spatial coordinates of the target brain region in the brain map, plan the route to the target brain region to meet the special requirements such as avoiding dangerous areas or taking into account other target areas at the same time. Convert this route into a polar coordinate system and adjust the coordinates according to the new "zero point position". By rotating the arc ruler 2, the positioning requirements of the special position can be achieved.
[0051] (6) After the positioning work is completed, remove the calibration pointer 5 and replace it with a metal electrode or glass electrode, etc., according to the experimental requirements, install the surgical tools such as metal electrodes or glass electrodes on the clamp assembly 8, and slowly insert the metal electrodes or glass electrodes into the target depth by rotating the screw. After waiting for several minutes until it is stable, tighten the corresponding pin screws to help fix the clamp assembly 8.
[0052] The above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation; it is neither necessary nor possible to exhaustively list all possible implementations. However, obvious variations or modifications derived therefrom remain within the scope of this technology.
Claims
1. An arc-shaped operating instrument for deep brain surgery in animals, characterized in that: Including the arc arm assembly and calibration platform (6); The calibration platform (6) includes an X-axis calibration block (61), a Y-axis calibration block (63), a Z-axis calibration block (64), and a calibration shaft seat (65). The X-axis calibration block (61) is connected to the X-axis slide (14) of the stereo positioning instrument (1) and can be adjusted in the X-axis position. The Y-axis calibration block (63) is connected to the X-axis calibration block (61) and can be adjusted in the Y-axis position. The Z-axis calibration block (64) is connected to the Y-axis calibration block (63) and can be adjusted in the Z-axis position. The calibration shaft seat (65) is fixed on the Z-axis calibration block (64). After the calibration platform (6) is installed, the axis of the calibration shaft is parallel to the Y-axis and passes through the zero point of the stereo positioning instrument (1). The X-axis, Y-axis, and Z-axis are perpendicular to each other. The arc arm assembly includes an arc ruler (2), a clamp assembly (8), and a radial adjuster (4); one end of the arc ruler (2) is connected to a calibration shaft seat (65) and can rotate about the axis of the calibration shaft, with the arc center of the arc ruler (2) coinciding with the zero point of the stereo positioning instrument (1); a slidable arc rail slider (3) is provided on the arc ruler (2); the radial adjuster (4) is mounted on the arc rail slider (3) and slides along the arc ruler (2); the clamp assembly (8) is mounted on the radial adjuster (4) and is adjusted by it to position itself radially on the arc ruler (2); a surgical tool or a calibration pointer (5) can be mounted on the clamp assembly (8), with the axes of the surgical tool and the calibration pointer (5) coinciding with the radial direction of the arc ruler (2); The stereo positioning device (1) is provided with a movable positioning lug (12), which is parallel to the Y direction. The movement trajectory of the positioning lug (12) is parallel to the Y direction, and the axis of the positioning lug (12) passes through the zero point of the stereo positioning device (1). The Z-axis calibration block (64) is provided with a calibration hole (641), which is coaxial with the calibration bearing (65). When the positioning lug (12) is inserted into the calibration hole (641), the calibration bearing (65) is coaxial with it. The radial adjuster (4) includes an adjustment platform (41), a radial adjustment knob (42), a threaded rod (43), a radial slide (44), and a guide rod (45); the threaded rod (43) and the guide rod (45) are parallel to the radial direction of the arc ruler (2); the threaded rod (43) is connected to the radial adjustment knob (42) and rotatably connected to the adjustment platform (41); the radial slide (44) is slidably engaged with the guide rod (45) and threadedly engaged with the threaded rod (43); the adjustment platform (41) is detachably connected to the slider fixed on the arc rail (3); The clamp assembly (8) includes an upper clamping arm (81), a radial seat rod (82), a lower clamping arm (83), and a clamp (84). The upper end of the radial seat rod (82) is connected to the radial slide (44) through the upper clamping arm (81). One end of the lower clamping arm (83) straightens the middle part of the radial seat rod (82), and the other end is connected to the adjustment table (41). The clamp (84) is connected to the lower end of the radial seat rod (82), and the clamping jaw of the clamp (84) is used to install surgical tools or adjust the pointer (5). The upper clamping arm (81) and the lower clamping arm (83) are provided with elongated holes, and a clamp is connected to the elongated holes. The clamp is used to connect the radial seat rod (82).
2. The arc-shaped operating instrument for deep brain surgery in animals according to claim 1, characterized in that: The X-axis calibration block (61) is L-shaped, and an X-axis adjustment knob (62) is provided on the X-axis calibration block (61). The screw connected to the X-axis adjustment knob (62) is threadedly connected to the X-axis slide (14).
3. The arc-shaped operating instrument for deep brain surgery in animals according to claim 1, characterized in that: The Y-axis calibration block (63) has a connection hole parallel to the Y-axis at one end connected to the X-axis calibration block (61), and the Z-axis calibration block (64) has a connection hole parallel to the Z-axis at one end connected to the Y-axis calibration block (63).
4. The arc-shaped operating instrument for deep brain surgery in animals according to claim 1, characterized in that: The end of the arc-shaped ruler (2) is fixedly connected to an adjusting chuck (7), which is sleeved on the calibration bearing (65). A clamping screw (71) for adjusting the clamping force is provided on the adjusting chuck (7).
5. The arc-shaped operating instrument for deep brain surgery in animals according to claim 4, characterized in that: A limiter is installed at the other end of the arc-shaped ruler (2), which is used to limit the sliding range of the surgical instruments and the adjustment pointer (5).