Hydrogen molecule slow-release type anti-inflammatory internal tampon and preparation method thereof

Abstract

The invention relates to the technical field of medical supplies, in particular to a hydrogen molecule slow release type anti-inflammatory internal tampon which comprises a main body, the main body is composed of an absorber and a wrapping layer wrapping the absorber, and a functional additive is arranged in the absorber. The functional additive is composed of an anti-inflammatory traditional Chinese medicine extract, a chemical bacteriostatic agent and magnesium hydride, the content of the magnesium hydride is 0.5-1.6 ppm, the magnesium hydride is uniformly dispersed in the absorber in the form of particles, and hydrogen is triggered to be slowly released through moisture; one end of the pull rope is connected with the wrapping layer; the outer wall of the guide pipe is smooth, the main body is located in the guide pipe, and the pull rope extends outwards through one end of the guide pipe. According to the invention, slow release of hydrogen is triggered by moisture, and the anti-inflammatory traditional Chinese medicine extract and the chemical bacteriostatic agent are combined, so that multiple effects of resisting inflammation, resisting oxidation, relieving pain, inhibiting bacteria and the like are realized.

Description

Technical Field

[0001] This invention relates to the field of medical supplies technology, specifically to a hydrogen molecule sustained-release anti-inflammatory tampon and its preparation method. Background Technology

[0002] Gynecological inflammation is a major issue affecting women's reproductive health. In promoting hydrogen therapy to improve gynecological inflammation, tumors, and infertility, we aim to revolutionize traditional treatments such as common medications (hormones and strong reducing agents) and surgical interventions, providing a non-invasive, low-side-effect, and highly safe alternative. The most distinctive feature of hydrogen molecule sustained-release anti-inflammatory tampons is their high biocompatibility. Their underlying technological principle is based on the well-established anti-inflammatory and antioxidant properties. Their anti-inflammatory effect can reduce inflammatory responses in the reproductive system. Hydrogen, as a selective antioxidant, can neutralize free radicals in the body, reducing oxidative stress damage to reproductive cells. These hydrogen molecule sustained-release anti-inflammatory tampons achieve targeted, high-volume, and continuous delivery of hydrogen molecules to the perineum, vagina, cervix, and uterus. In addition to its anti-inflammatory and antioxidant effects, hydrogen also has significant analgesic effects, relieving menstrual pain, improving cell function, and enhancing the microenvironment. Based on ingredients such as magnesium hydride, motherwort, mugwort, and angelica, it can effectively relieve dysmenorrhea and inflammation, thereby improving reproductive health. Summary of the Invention

[0003] This invention provides a hydrogen molecule sustained-release anti-inflammatory tampon for internal use, which releases hydrogen gas through moisture triggering, and combines it with anti-inflammatory traditional Chinese medicine extracts and chemical antibacterial agents to achieve multiple effects such as anti-inflammatory, antioxidant, analgesic, antibacterial, and anti-tumor.

[0004] To achieve the above objectives, the present invention provides the following technical solution: a hydrogen molecule sustained-release anti-inflammatory tampon, comprising: a main body, the main body being composed of an absorbent body and a covering layer encapsulating the absorbent body, and the absorbent body containing a functional additive, the functional additive being composed of an anti-inflammatory traditional Chinese medicine extract, a chemical antibacterial agent, and magnesium hydride, the magnesium hydride being 0.5-1.6 ppm and uniformly dispersed in the absorbent body in the form of microparticles, releasing hydrogen gas through moisture triggering; a pull cord, one end of the pull cord being connected to the covering layer; and a catheter, the outer wall of the catheter being smooth, and the main body being located inside the catheter, the pull cord extending outward from one end of the catheter.

[0005] Preferably, the absorbent is composed of natural cotton fibers and viscose fibers, wherein the mass ratio of natural cotton fibers to viscose fibers is 7:3 to 9:1.

[0006] Preferably, the anti-inflammatory traditional Chinese medicine extract comprises: 6-12 parts by weight of Leonurus japonicus, 2-8 parts by weight of Artemisia argyi, and 3-6 parts by weight of Angelica sinensis; the anti-inflammatory traditional Chinese medicine extract is atomized and sprayed onto the absorbent body at a spraying pressure of 0.1-0.3 MPa, and dried and cured at 60 degrees Celsius.

[0007] Preferably, the chemical antibacterial agent includes an organic acid and a physical regulator; the organic acid is lactic acid, and the physical regulator is far-infrared ceramic powder.

[0008] Preferably, the wrapping layer is made of a breathable membrane or non-woven fabric with a thickness of ≤0.1 mm and has liquid permeability.

[0009] Preferably, the pull rope is made of cotton or polyester thread with a length of 8 to 15 centimeters and has a tensile strength of ≥2.5 kg.

[0010] Preferably, the catheter is made of medical-grade polyethylene or polypropylene.

[0011] Preferably, the magnesium hydride microparticles are coated with a slow-release coating of varying thicknesses.

[0012] Preferably, a preparation method for preparing hydrogen molecule sustained-release anti-inflammatory tampons includes the following steps:

[0013] Step 1: Raw material pretreatment, in which natural cotton fibers are boiled, desized, and softened in a caustic soda solution;

[0014] Step 2: Fiber forming, mixing natural cotton fibers and viscose fibers, followed by carding, web laying and high-pressure hydroentangling reinforcement;

[0015] Step 3: Functional processing. The anti-inflammatory Chinese herbal extract is atomized and sprayed onto the absorbent and dried and solidified. Magnesium hydride particles with different sustained-release coating thicknesses are mixed and dispersed into the absorbent by air jet or mechanical stirring.

[0016] Step 4: Assembly and compression. The main body is wound and shaped and placed inside the conduit, and the ends are beveled.

[0017] Step 5: Sterilization and packaging. After sterilization with ethylene oxide or irradiation, the products are individually sealed and packaged.

[0018] The beneficial effects of this invention are as follows: This tampon releases hydrogen gas slowly through moisture triggering, and combines it with anti-inflammatory traditional Chinese medicine extracts and chemical antibacterial agents to achieve multiple effects such as anti-inflammation, anti-oxidation, analgesia, antibacterial properties, and potential anti-tumor activity. The specific mechanism is as follows: Magnesium hydride (MgH2) particles are dispersed in the absorbent body. Upon encountering moisture in the vagina / perineum, they undergo a hydrolysis reaction and release hydrogen gas. The released hydrogen gas has selective antioxidant capacity, which can effectively scavenge harmful free radicals such as ·OH and ONOO-, reducing the damage of oxidative stress to reproductive cells. In addition, hydrogen gas can also inhibit inflammatory pathways such as NF-κB, reduce pro-inflammatory factors such as IL-6 and TNF-α, alleviate chronic inflammation, and thus play a potential role in the prevention and treatment of tumors. Furthermore, it can regulate cell membrane permeability, improve local microcirculation, and relieve menstrual pain.

[0019] Anti-inflammatory herbal extracts are used for synergistic effects. Motherwort invigorates blood circulation and regulates menstruation, relieving uterine spasmodic pain. Artemisia argyi warms the meridians and dispels cold, inhibiting pathogenic bacteria such as Staphylococcus aureus. Angelica sinensis nourishes and invigorates blood, promoting tissue repair. Atomized spraying technology ensures uniform loading and stable release of the medicinal effects.

[0020] The combination of chemical antibacterial agents and anti-inflammatory traditional Chinese medicine extracts provides dual protection. The lactic acid in the formula regulates the vaginal pH to 3.8–4.5, inhibiting pathogenic microorganisms such as Candida and Gardnerella vaginalis. Far-infrared ceramic powder radiates far-infrared rays (8–14 μm), promoting local blood circulation and enhancing cell metabolism.

[0021] The breathable coating layer ensures liquid permeability while preventing hydrogen from escaping too quickly. With the slow-release control technology, magnesium hydride microparticles are coated with slow-release coatings of different thicknesses to achieve gradient release of hydrogen, resulting in rapid initial effect and sustained action in the later stages.

[0022] The technology can be expanded to include male applications. Although initially designed for women's gynecological health and reproductive improvement, this technology, after adjustment, can be extended to the adjuvant treatment of colorectal cancer and the improvement of male urogenital health through rectal administration (similar to suppositories). The anti-tumor effects of hydrogen have been demonstrated in multiple studies; local administration can increase hydrogen concentration and improve efficacy. In male infertility and sexual dysfunction, hydrogen therapy improves sperm quality and erectile function through antioxidant mechanisms, contributing to eugenics and population structure optimization. Multicenter clinical trials have shown a side effect rate of <0.01%, overcoming the invasiveness of traditional hormone replacement therapy. In prostatitis / chronic pelvic pain syndrome (CPPS), hydrogen slow-release inhibits prostate inflammation, relieves perineal pain, and improves urinary retention symptoms. In patients with urethritis / balanitis, local application with tampons utilizes lactic acid for antibacterial activity combined with hydrogen for anti-inflammatory effects, reducing antibiotic dependence. In addition, when used by men, the shape can be optimized, such as by changing to a short suppository or patch, and the magnesium hydride concentration can be finely adjusted to suit the slightly higher tolerance of male mucous membranes.

[0023] Therefore, this tampon uses a non-invasive approach to replace hormones / antibiotics, reducing the risk of drug resistance. It precisely delivers hydrogen gas to the lesion, achieving a highly effective local therapeutic effect through its strong penetrability. Through a multi-mechanism synergy, chemical antibacterial agents, traditional Chinese medicine conditioning, and physical regulation cover multiple aspects of inflammation. Its sustained-release coating technology ensures stable hydrogen release for 12-24 hours, making it suitable for daily use. This solution is clearly innovative in the field of women's reproductive health and has the potential to expand into the men's market. Attached Figure Description

[0024] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0025] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0026] Figure 2 This is a cross-sectional view of the main body of the present invention. Detailed Implementation

[0027] The technical solution of the present invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0028] according to Figure 1 , Figure 2As shown, a hydrogen molecule sustained-release anti-inflammatory tampon includes: a main body 1, which is composed of an absorbent body 2 and a wrapping layer 3 covering the outside of the absorbent body 2, and the absorbent body 2 contains functional additives. The absorbent body 2 is composed of natural cotton fibers and viscose fibers, with a mass ratio of natural cotton fibers to viscose fibers of 7:3 to 9:1. The wrapping layer 3 is composed of a breathable membrane or non-woven fabric with a thickness ≤0.1 mm and is liquid permeable. The functional additives consist of an anti-inflammatory traditional Chinese medicine extract 4, a chemical antibacterial agent 5, and magnesium hydride 6. The anti-inflammatory traditional Chinese medicine extract 4 includes extracts of 6-12 parts by mass of Leonurus japonicus, 2-8 parts by mass of Artemisia argyi, and 3-6 parts by mass of Angelica sinensis; the anti-inflammatory traditional Chinese medicine extract 4 is atomized and sprayed into the absorbent body 2 at a spraying pressure of 0.1-0.3 MPa and dried and cured at 60 degrees Celsius. The chemical antibacterial agent 5 includes an organic acid and a physical regulator; the organic acid is lactic acid, and the physical regulator is far-infrared ceramic powder. The magnesium hydride 6 is 0.5–1.6 ppm and is uniformly dispersed in particulate form within the absorber 2, releasing hydrogen gas through moisture triggering. The magnesium hydride 6 particles are coated with a slow-release coating of varying thicknesses. A pull cord 7 is attached to the wrapping layer 3 at one end and is made of cotton or polyester thread with a length of 8–15 cm and a tensile strength ≥2.5 kg. A catheter 8 is made of medical-grade polyethylene or polypropylene with a smooth wall. The main body 1 is located inside the catheter 8, and the pull cord 7 extends outward from one end of the catheter 8.

[0029] A method for preparing hydrogen molecule sustained-release anti-inflammatory tampons for internal use includes the following steps:

[0030] Step 1: Raw material pretreatment, in which natural cotton fibers are boiled, desized, and softened in a caustic soda solution;

[0031] Step 2: Fiber forming, mixing natural cotton fibers and viscose fibers, followed by carding, web laying and high-pressure hydroentangling reinforcement;

[0032] Step 3: Functional processing. The anti-inflammatory Chinese herbal extract is atomized and sprayed into the absorber 2 and dried and solidified. Magnesium hydride 6 particles with different sustained-release coating thicknesses are mixed and dispersed into the absorber 2 by air jet or mechanical stirring.

[0033] Step 4: Assembly and compression. The main body 1 is wound and shaped and placed inside the conduit 8, and the ends are beveled.

[0034] Step 5: Sterilization and packaging. After sterilization with ethylene oxide or irradiation, the products are individually sealed and packaged.

[0035] This tampon releases hydrogen through moisture-triggered slow release, combined with an anti-inflammatory traditional Chinese medicine extract 4 and a chemical antibacterial agent 5, achieving multiple effects including anti-inflammatory, antioxidant, analgesic, antibacterial, and potential anti-tumor properties. The specific mechanism is as follows: Magnesium hydride (6MgH2) particles are dispersed within the absorbent body 2. Upon contact with vaginal / perineal moisture, they undergo a hydrolysis reaction, releasing hydrogen gas. This released hydrogen gas has selective antioxidant capabilities, effectively scavenging harmful free radicals such as ·OH and ONOO-, reducing oxidative stress damage to reproductive cells. Furthermore, hydrogen gas can inhibit inflammatory pathways such as NF-κB, reduce pro-inflammatory factors such as IL-6 and TNF-α, alleviate chronic inflammation, and thus potentially play a role in preventing and treating tumors. It can also regulate cell membrane permeability, improve local microcirculation, and relieve menstrual pain.

[0036] Four anti-inflammatory herbal extracts are used for synergistic effects. Motherwort invigorates blood circulation and regulates menstruation, relieving uterine spasmodic pain. Artemisia argyi warms the meridians and dispels cold, inhibiting pathogenic bacteria such as Staphylococcus aureus. Angelica sinensis nourishes and invigorates blood, promoting tissue repair. Uniform loading through atomized spraying technology ensures stable release of the medicinal effects.

[0037] The combination of chemical antibacterial agent 5 and anti-inflammatory traditional Chinese medicine extract 4 provides dual protection. The lactic acid in the extract regulates the vaginal pH to 3.8–4.5, inhibiting pathogenic microorganisms such as Candida and Gardnerella vaginalis. Far-infrared ceramic powder radiates far-infrared rays at 8–14 μm, promoting local blood circulation and enhancing cell metabolism.

[0038] The breathable coating layer 3 ensures liquid permeability while preventing hydrogen from escaping too quickly. Under the slow-release control technology, magnesium hydride 6 particles are coated with slow-release coatings of different thicknesses, wherein the thickness of the slow-release coating is preferably 0.1 mm, 0.5 mm, 0.7 mm, and 0.8 mm, thereby achieving gradient release of hydrogen, with rapid initial effect and sustained effect in the later stage.

[0039] The technology can be expanded to include male applications. Although initially designed for women's gynecological health and reproductive improvement, this technology, after adjustment, can be extended to the adjuvant treatment of colorectal cancer and the improvement of male urogenital health through rectal administration (similar to suppositories). The anti-tumor effects of hydrogen have been demonstrated in multiple studies; local administration can increase hydrogen concentration and improve efficacy. In male infertility and sexual dysfunction, hydrogen therapy improves sperm quality and erectile function through antioxidant mechanisms, contributing to eugenics and population structure optimization. Multicenter clinical trials have shown a side effect rate of <0.01%, overcoming the invasiveness of traditional hormone replacement therapy. In prostatitis / chronic pelvic pain syndrome (CPPS), hydrogen slow-release inhibits prostate inflammation, relieves perineal pain, and improves urinary retention symptoms. In patients with urethritis / balanitis, local application with tampons utilizes lactic acid for antibacterial activity combined with hydrogen for anti-inflammatory effects, reducing antibiotic dependence. In addition, when used by men, the shape can be optimized, such as by changing to a short suppository or patch, and the magnesium hydride concentration can be finely adjusted to suit the slightly higher tolerance of male mucous membranes.

[0040] Therefore, this tampon uses a non-invasive approach to replace hormones / antibiotics, reducing the risk of drug resistance. It precisely delivers hydrogen to the lesion, avoiding systemic side effects. Through a multi-mechanism synergy, chemical antibacterial agents, traditional Chinese medicine conditioning, and physical regulation cover multiple aspects of inflammation. Its sustained-release coating technology ensures stable hydrogen release for 12-24 hours, making it suitable for daily use. This solution is clearly innovative in the field of women's reproductive health and has the potential to expand into the men's market.

[0041] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the scope of the claims.

Claims

1. A hydrogen molecule sustained-release anti-inflammatory tampon for internal use, characterized in that, include: The main body (1) is composed of an absorber (2) and a wrapping layer (3) covering the outside of the absorber (2). The absorber (2) contains a functional additive, which is composed of an anti-inflammatory Chinese herbal extract (4), a chemical antibacterial agent (5), and magnesium hydride (6). The magnesium hydride (6) is 0.5 to 1.6 ppm and is uniformly dispersed in the absorber (2) in the form of particles. It releases hydrogen gas slowly through moisture triggering. A pull cord (7), one end of which is connected to the wrapping layer (3); The conduit (8) has a smooth outer wall, and the body (1) is located inside the conduit (8), and the pull rope (7) extends outward from one end of the conduit (8).

2. The hydrogen molecule sustained-release anti-inflammatory tampon according to claim 1, characterized in that, The absorber (2) is composed of natural cotton fiber and viscose fiber, and the mass ratio of natural cotton fiber to viscose fiber is 7:3 to 9:

1.

3. The hydrogen molecule sustained-release anti-inflammatory tampon according to claim 1, characterized in that, The anti-inflammatory Chinese herbal extract (4) includes: 6-12 parts by weight of Leonurus japonicus, 2-8 parts by weight of Artemisia argyi, and 3-6 parts by weight of Angelica sinensis; the anti-inflammatory Chinese herbal extract (4) is sprayed into the absorber (2) by atomization at a pressure of 0.1-0.3 MPa and dried and cured at 60 degrees Celsius.

4. The hydrogen molecule sustained-release anti-inflammatory tampon according to claim 1, characterized in that, The chemical antibacterial agent (5) includes an organic acid and a physical regulator; the organic acid is lactic acid, and the physical regulator is far-infrared ceramic powder.

5. The hydrogen molecule sustained-release anti-inflammatory tampon according to claim 1, characterized in that, The wrapping layer (3) is made of a breathable membrane or non-woven fabric with a thickness of ≤0.1 mm and is liquid permeable.

6. The hydrogen molecule sustained-release anti-inflammatory tampon according to claim 1, characterized in that, The pull rope (7) is made of cotton or polyester thread with a length of 8 to 15 cm and has a tensile strength of ≥2.5 kg.

7. The hydrogen molecule sustained-release anti-inflammatory tampon according to claim 1, characterized in that, The catheter (8) is made of medical-grade polyethylene or polypropylene.

8. The hydrogen molecule sustained-release anti-inflammatory tampon according to claim 1, characterized in that, The magnesium hydride (6) particles are coated with slow-release coatings of varying thicknesses.

9. A preparation method for preparing the hydrogen molecule sustained-release anti-inflammatory tampons as described in claims 1 to 8, characterized in that, Includes the following steps: Step 1: Raw material pretreatment, in which natural cotton fibers are boiled, desized, and softened in a caustic soda solution; Step 2: Fiber forming, mixing natural cotton fibers and viscose fibers, followed by carding, web laying and high-pressure hydroentangling reinforcement; Step 3: Functional processing. The anti-inflammatory Chinese herbal extract is atomized and sprayed into the absorber (2) and dried and solidified. Magnesium hydride (6) particles with different sustained-release coating thicknesses are mixed and dispersed into the absorber (2) by air jet or mechanical stirring. Step 4: Assembly and compression. The main body (1) is wound and shaped and placed inside the conduit (8), and the ends are beveled. Step 5: Sterilization and packaging. After sterilization with ethylene oxide or irradiation, the products are individually sealed and packaged.

Images