Allergy-relieving, swelling-eliminating and itching-relieving mixture and production process thereof

By combining plant extracts with 1,3-propanediol and employing ultrasonic extraction technology, the problem of low extraction rate of effective ingredients in natural compound preparations has been solved, achieving highly efficient and stable soothing, swelling-reducing, and antipruritic effects, making it suitable for a variety of cosmetics.

CN120837404APending Publication Date: 2025-10-28BEIJING YUSHENGTANG BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202511034367.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-25
Publication Date
2025-10-28

AI Technical Summary

Technical Problem

Existing natural ingredient compound preparations have low extraction rates of active ingredients and poor formulation stability, while long-term use of chemically synthesized ingredients poses a risk of irritation.

Method used

Extracts from plants such as purslane, licorice, dandelion, scutellaria, and gentian are combined with 1,3-propanediol and water, and then processed using ultrasonic extraction and vacuum distillation. After fine filtration and blending, the mixture is sterilized and filled to control product quality.

Benefits of technology

It improves the dissolution rate of active ingredients and product stability, reduces the risk of irritation from chemically synthesized ingredients, is suitable for sensitive skin, and is applicable to various types of cosmetics.

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Abstract

The invention discloses an allergy-relieving, swelling-eliminating and itching-relieving mixture and a production process thereof. The mixture takes 1, 3-propylene glycol and water as matrixes, is compounded with plant extracts such as purslane, liquorice, dandelion, scutellaria baicalensis and gentiana scabra bunge, has the effects of relieving allergy, diminishing swelling and relieving itching, and is suitable for resident and drip washing cosmetics. The production process adopts an ultrasonic extraction technology and comprises the steps of raw material pretreatment, ultrasonic extraction, solvent recovery, refined filtration and blending, sterilization and filling, and the finished product meets the safety control standards of heavy metals, microorganisms, pesticide residues and the like.
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Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, specifically to a soothing, swelling-reducing, and itch-relieving compound and its manufacturing process. Background Technology

[0002] Currently, most soothing cosmetics for sensitive skin on the market use chemically synthesized ingredients. While these can relieve symptoms in the short term, long-term use may pose a risk of irritation. Natural plant extracts, due to their gentle and low-irritant properties, are gradually becoming a focus of research and development for soothing products. However, existing natural ingredient compound preparations often suffer from low extraction rates of active ingredients and poor formula stability, necessitating improvements in process optimization and scientific ingredient formulation to enhance product efficacy.

[0003] Therefore, we propose a soothing, swelling-reducing, and antipruritic compound and its production process to address the problems mentioned above. Summary of the Invention

[0004] The purpose of this invention is to provide a soothing, swelling-reducing, and antipruritic compound and its manufacturing process, in order to solve the problem mentioned in the background art that the natural ingredient compound preparations for reducing swelling and relieving itching on the market often have low extraction rates of effective ingredients.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a soothing, swelling-reducing, and antipruritic compound, composed of the following ingredients by weight percentage: 1,3-Propylene glycol: 55-65%, typical value 60.85% Water: 30-40%, typical value 35% Purslane (Portulaca oleracea) extract: 0.8-1.2%, typical value 1%. Licorice (Glycyrrhiza uralensis) root extract: 0.8-1.2%, typical value 1%. Dandelion (TARAXACUM MONGOLICUM) extract: 0.8-1.2%, typical value 1%. Scutellaria baicalensis root extract: 0.8-1.2%, typical value 1%. Gentian (Gentiana scabra) extract: 0.12-0.18%, typical value 0.15%.

[0006] A manufacturing process for a soothing, swelling-reducing, and antipruritic compound includes the following steps: Raw material pretreatment: The whole plants of purslane, gentian, and dandelion, as well as the roots of licorice and scutellaria, are sorted, impurities are removed, and then they are washed, dried and crushed to a suitable particle size.

[0007] Ultrasonic extraction: The pulverized plant material is added to an ethanol solution and 1,3-propanediol, and ultrasonic extraction is performed. The specific parameters are optimized and determined according to the characteristics of the raw material.

[0008] Solvent recovery: The extract is subjected to vacuum distillation to recover the ethanol solvent and increase the concentration of active ingredients.

[0009] Fine filtration and preparation: The extract after solvent recovery is finely filtered to remove impurities, and water and other excipients are added according to the formula ratio and stirred evenly for preparation.

[0010] Sterilization and filling: The prepared mixture is sterilized and then filled and packaged in a sterile environment.

[0011] Product Usage This compound can be used as a skin protectant in the preparation of leave-on or rinse-off cosmetics, with a recommended addition amount of 1-10%.

[0012] IV. Quality Control Indicators Appearance requirements: Yellow to yellowish-brown transparent liquid with a characteristic odor.

[0013] Physicochemical properties: Soluble solids: controlled by refractive index testing.

[0014] Solid content: ≥55%, determined by refractive index method.

[0015] Content of indicative components (flavonoids): ≥0.5%, detected by spectrophotometry.

[0016] Safety indicators: Heavy metal limits: lead < 10 mg / kg, mercury < 1 mg / kg, arsenic < 2 mg / kg, cadmium < 5 mg / kg.

[0017] Microbial limits: Total bacterial count < 100 CFU / mL, total mold and yeast count < 10 CFU / mL, and thermotolerant coliforms, Staphylococcus aureus, and Pseudomonas aeruginosa must not be detected.

[0018] Pesticide residue limits: Residues of multiple pesticides, including α-hexachlorocyclohexane, β-hexachlorocyclohexane, δ-hexachlorocyclohexane, and chlordane, are all <1 mg / kg.

[0019] Methanol limit: ≤2000mg / kg.

[0020] Compared with the prior art, the beneficial effects of the present invention are: the soothing, swelling-reducing and antipruritic compound is made of natural and mild ingredients: plant extracts are the main active ingredients, combined with 1,3-propanediol and water, which reduces the irritation of chemically synthesized ingredients and is suitable for use on sensitive skin.

[0021] Synergistic effects: The combination of extracts from purslane, licorice and other herbs has soothing, anti-inflammatory and antioxidant effects, which can effectively relieve discomfort symptoms such as skin redness, swelling and itching.

[0022] Highly efficient and stable process: Ultrasonic extraction technology can improve the dissolution rate of plant active ingredients, and the production process is sterilized to ensure the product's microbial safety and good stability.

[0023] Wide range of applications: Suitable for leave-on cosmetics such as face creams and lotions, as well as rinse-off products such as facial cleansers and shower gels, offering flexible usage options. Attached Figure Description

[0024] Figure 1 This is a schematic diagram illustrating the heavy metal risk limits of the present invention; Figure 2 This is a schematic diagram illustrating the microbial risk limits of the present invention; Figure 3 This is a schematic diagram illustrating the pesticide residue risk limit of the present invention; Figure 4 This is a schematic diagram illustrating the source of the extract of the present invention. Detailed Implementation

[0025] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention. Example 1

[0026] Formula: 60.85 kg of 1,3-propylene glycol, 35 kg of water, 1 kg of purslane extract, 1 kg of licorice root extract, 1 kg of dandelion extract, 1 kg of scutellaria root extract, and 0.15 kg of gentian extract.

[0027] Process: After the raw materials are crushed, 80% ethanol and 1,3-propanediol are added, and ultrasonic extraction is performed at 50℃ and 300W for 30 minutes. After recovering the ethanol, the mixture is finely filtered and blended, sterilized at 121℃ for 20 minutes, and then filled. Example 2

[0028] Formula: 55kg of 1,3-propylene glycol, 40kg of water, 0.8kg of purslane extract, 0.8kg of licorice root extract, 0.8kg of dandelion extract, 0.8kg of scutellaria root extract, and 0.12kg of gentian extract.

[0029] Process: Extraction with 70% ethanol, ultrasonic extraction at 45℃ and 250W for 40 minutes, the remaining steps are the same as in Example 1.

[0030] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A soothing, swelling-reducing, and antipruritic compound, characterized in that, It consists of the following components by weight percentage: 1,3-Propane glycol: 55-65%; Water: 30-40%; Purslane extract: 0.8-1.2%; Licorice root extract: 0.8-1.2%; Dandelion extract: 0.8-1.2%; Scutellaria baicalensis root extract: 0.8-1.2%; Gentian extract: 0.12-0.18%.

2. The soothing, swelling-reducing, and antipruritic compound according to claim 1, characterized in that: The purslane extract, licorice root extract, dandelion extract, scutellaria root extract, and gentian extract are all solvent extracts of the whole plant or root.

3. A production process for the soothing, swelling-reducing, and antipruritic compound as described in any one of claims 1-2, characterized in that, Includes the following steps: Plant materials are sorted, washed, dried, and crushed; The mixture was extracted with ethanol solution and 1,3-propanediol by ultrasonic extraction. Recover the solvent, filter it thoroughly, and then blend it. Sterilization and filling.

4. The production process according to claim 3, characterized in that, The ultrasonic extraction temperature is 45-50℃, the ultrasonic power is 250-300W, and the extraction time is 30-40 minutes.

5. The production process according to claim 3, characterized in that, The sterilization method is moist heat sterilization, and the conditions are sterilization at 121°C for 20 minutes.