Device and method for rapidly screening allergens of skin care products for infants and children

Abstract

The invention belongs to the technical field of allergen screening devices, and discloses an infant skin care product allergen rapid screening device which comprises a kit and a placing mechanism installed on an allergen detector, and the placing mechanism comprises a moving assembly and a first adjusting assembly; the moving assembly comprises a limiting box which is fixedly installed on the allergen detector, and a moving column is installed on the limiting box in a sliding mode. The friction block is slidably mounted in the limiting box; the placing mechanism is provided with a moving assembly and a first adjusting assembly, and in the complete stage of inserting the kit into the allergen detector, the first adjusting assembly can dynamically drive a friction block in a limiting box based on the insertion depth to apply gradient pressure to a moving column slidably mounted on a first gear; the moving speed of the kit is matched with the speed required by the initial stage, the stable stage and the tail end buffer stage, so that the equipment and the kit structure are protected, and the stability and the accuracy of the detection process are guaranteed.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of allergen screening devices, and particularly relates to a baby skin care product allergen rapid screening device and method. BACKGROUND

[0002] The skin of the baby group is in a key stage of growth and development, the skin barrier function thereof is not yet mature, the sebaceous gland secretion function thereof is weak, and the resistance to external stimulation is far lower than that of adults; and the baby skin care product is a daily product directly contacting the skin, and if the baby skin care product contains sensitive components such as fragrances, preservatives and plant extracts, the sensitive components can easily penetrate the weak skin barrier to cause an immune response, resulting in local allergic symptoms such as erythema, papules and itching, and in severe cases, swelling, exudation and even systemic allergic reactions can occur, affecting the healthy growth and life quality of the baby.

[0003] Therefore, accurate identification of potential allergens in baby skin care products through professional allergen screening technology has become a key link to ensure the safety of baby skin. In the prior art, allergen detectors and kits are mainly used for screening operations. In the operation process, the insertion of the kit is mainly completed by manual pushing. Specifically, the operator needs to immerse the swab of the kit in the sample liquid for a certain period of time, and then manually push the kit into the allergen detector to start the detection.

[0004] However, this manual insertion method has obvious defects. The insertion speed is completely affected by subjective factors such as the operator's personal habits, strength control ability and fatigue level, showing significant randomness. The operator may push too fast due to the urgency of completing the operation, the speed may fluctuate greatly due to uneven force, and the speed may suddenly slow down or even stop due to the fear of the kit being stuck or damaging the instrument. This disordered speed mode not only causes the kit to be buckled and collide with the guide rail of the detector, the end of the kit to be rigidly impacted with the sensor inside the detector, but also destroys the dynamic balance of the sample flow rate and the NC membrane adsorption capacity, causing problems such as uneven sample chromatography and color deviation, which seriously affects the reliability, repeatability and consistency of the detection results, and also shortens the service life of the instrument and the kit. SUMMARY

[0005] The purpose of the present application is to provide a baby skin care product allergen rapid screening device and method to solve the technical problems in the prior art that allergen screening relies on a detector and a kit, but the insertion is manual, the speed is random, mechanical damage is easy to occur, the detection result is unreliable, and the service life of the equipment is shortened.

[0006] In order to achieve the above purpose, the present application adopts the following technical solutions: The application discloses a device for rapidly screening allergens of baby skin care products, which comprises a reagent box and a placing mechanism installed on an allergen detector.

[0007] Preferably, the moving assembly further comprises a first spring sleeved on the moving column and fixedly connected with the limiting box, a first magnetic block slidingly installed on the limiting box and fixedly connected with the friction block, two connecting blocks fixedly installed on two sides of the first magnetic block and connected with the limiting box through a second spring, and two first sliding rods slidingly connected with the two connecting blocks and fixedly connected with the limiting box.

[0008] Preferably, the first adjusting assembly comprises a mounting plate fixedly installed on the allergen detector, a first rotating shaft and a second rotating shaft rotatably installed on the mounting plate, a transmission disc fixedly installed on the second rotating shaft and provided with a knob column, and a grooved wheel fixedly installed on the first rotating shaft and matched with the transmission disc.

[0009] Preferably, the first adjusting assembly further comprises a mounting seat fixedly installed on the mounting plate, a third rotating shaft rotatably installed on the mounting seat, a second bevel gear fixedly installed on one end of the third rotating shaft, a second gear fixedly installed on the other end of the third rotating shaft, a first bevel gear fixedly installed on the second rotating shaft and engaged with the second bevel gear, and a rack engaged with the second gear.

[0010] Preferably, the first adjusting assembly further comprises a mounting disc fixedly installed on the first rotating shaft and provided with a plurality of second magnetic blocks.

[0011] Preferably, the placing mechanism further comprises a driving assembly, and the driving assembly comprises a containing box slidingly installed on the allergen detector and provided with a hollow box, the hollow box is fixedly connected with the moving column and the first spring, and a protective cover is fixedly installed on the hollow box.

[0012] Preferably, the driving assembly further comprises a folding air bag used for connecting the hollow box with the allergen detector, a first connecting pipe fixedly installed on the hollow box and provided with a hollow disc, a rotating pipe rotatably installed on the hollow disc and provided with a driving box, and a bent pipe fixedly installed on the driving box and provided with a jet nozzle in threaded connection.

[0013] Preferably, the placing mechanism further comprises a clamping assembly, the clamping assembly comprising: a first fixed plate fixedly installed on the storage box, a plurality of fixed boxes fixedly installed inside the first fixed plate; a first screw rotatably installed on the fixed box, a first gear fixedly installed at one end of the first screw, and a first threaded plate threadedly connected to the other end of the first screw and slidably connected to the fixed box; a connecting box fixedly installed inside the fixed box, an inflatable air bag fixedly installed on the connecting box; a crown gear meshingly connected with the first gear and fixedly connected with the driving box.

[0014] Preferably, the placing mechanism further comprises a second adjusting assembly, the second adjusting assembly comprising: a first moving plate fixedly connected with the moving column and the rack, a second slide rod fixedly installed on the first moving plate; a second fixed plate fixedly installed on the allergen detector, a second screw threadedly connected to the second fixed plate; a second moving plate slidably connected with the second slide rod, threadedly connected with the second screw, and connected with the first moving plate through a fourth spring.

[0015] The use method of the infant skin care product allergen rapid screening device comprises the following steps: Step one, preloading: pull out the hollow box to drive the moving column and the rack to extend synchronously, and place the disposable reagent box in the center groove of the first fixed plate; after releasing the hand, the folded air bag is compressed, the airflow drives the crown gear to rotate through the driving box, the four-way inflatable air bag is inflated synchronously, and the reagent box is automatically centered and clamped; Step two, gradient insertion: the moving column is retracted under the combined action of the spring and the magnetic force; the four magnetic blocks with decreasing magnetic force are sequentially close to the first magnetic block, so that the friction block generates three-stage gradient pressure on the moving column, corresponding to the whole process of low-speed collision avoidance, uniform-speed stable lamination and end buffer deceleration of the reagent box insertion; Step three, speed fine adjustment: rotate the second screw in the clockwise direction to increase the pre-tightening force of the fourth spring, so as to realize the increase or decrease of the insertion speed of the reagent box in the complete stage of insertion into the allergen detector; Step four, automatic detection: after the reagent box is completely in place, the allergen detector automatically completes the antigen-antibody reaction, washing and color development process.

[0016] In summary, due to the adoption of the above technical solutions, the present application has the following advantages: 1. The placing mechanism in the application can dynamically drive the friction block in the limiting box based on the insertion depth through the setting of the moving assembly and the first adjusting assembly, so as to apply gradient pressure on the moving column slidingly installed on the first gear; the moving speed of the reagent box can be matched with the speed required in the initial stage, the stable stage and the terminal buffer stage, so that the reagent box can reduce the collision between the reagent box buckle and the instrument guide rail in the initial stage, ensure that the internal components of the reagent box are tightly matched with the detection area in the stable stage, and buffer the contact between the reagent box and the sensor in the terminal stage, thereby protecting the equipment and the reagent box structure and guaranteeing the stability and accuracy of the detection process.

[0017] 2. The placing mechanism in the application can move and extrude the folded air bag through the setting of the clamping assembly, so that the gas in the folded air bag enters the driving box through the first connecting pipe, the gas is sprayed out of the elbow pipe to drive the driving box to rotate, and the crown gear, the first gear and the first screw are driven to rotate, so that the first threaded plate extrudes the gas to the inflated air bag; the inflated air bag limits the reagent box from four directions, adapts to different sizes of reagent boxes, copes with the wear of the fixed plate, and ensures that the reagent box is accurately inserted into the allergen detector, thereby improving the detection stability.

[0018] 3. The placing mechanism in the application can drive the second moving plate to move along the second slide rod by rotating the second screw, adjust the stretching degree of the fourth spring, and change the elastic force that the moving column needs to overcome; while maintaining the staged speed mode, the overall insertion speed of the reagent box can be controlled according to the demand, the speed can be accelerated when the detection amount is large, the adaptability of screening efficiency is improved, and the demand of different scenes is met. DETAILED DESCRIPTION

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or the prior art description. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0020] Figure 1 It is a first assembly structure diagram of the present application; Figure 2 It is a second assembly structure diagram of the present application; Figure 3 It is a structure diagram of the clamping assembly in the present application; Figure 4 It is an internal structure diagram of the fixed box in the present application; Figure 5 It is a third assembly structure diagram of the present application; Figure 6The assembly structure diagram of the first adjusting assembly and the second adjusting assembly in the application; Figure 7 The structure diagram of the first adjusting assembly in the application; Figure 8 The internal structure diagram of the limiting box in the application; Figure 9 The assembly structure diagram of the folding air bag and the driving box in the application; Figure 10 The assembly structure diagram of the first connecting pipe and the air jet nozzle in the application.

[0021] The figure mark: 100, allergen detector; 200, placing mechanism; 211, protective cover; 212, first connecting pipe; 213, hollow box; 214, storage box; 215, elbow pipe; 216, hollow disc; 217, driving box; 218, rotating pipe; 219, folding air bag; 2191, air jet nozzle; 221, crown gear; 222, first fixed plate; 223, first gear; 224, fixed box; 225, first screw rod; 226, first threaded plate; 227, inflatable air bag; 228, connecting box; 231, moving column; 232, first spring; 233, limiting box; 234, first magnetic block; 235, second spring; 236, connecting block; 237, first sliding rod; 238, friction block; 241, rack; 242, mounting plate; 243, first rotating shaft; 244, pushing column; 245, first bevel gear; 246, transmission disc; 247, second rotating shaft; 248, mounting seat; 249, grooved wheel; 2491, third rotating shaft; 2492, second bevel gear; 2493, second magnetic block; 2494, mounting disc; 2495, second gear; 251, first moving plate; 252, fourth spring; 253, second sliding rod; 254, second moving plate; 255, second fixed plate; 256, second screw rod; 300, reagent box. DETAILED DESCRIPTION

[0022] In order to make the above-mentioned purpose, features and advantages of the application more obvious and easy to understand, the specific embodiments of the application will be described in detail below in combination with the drawings of the specification. Obviously, the described embodiments are part of the embodiments of the application, rather than all the embodiments. Based on the embodiments in the application, all other embodiments obtained by those skilled in the art without creative labor should belong to the protection scope of the application.

[0023] In the following description, many specific details are set forth in order to provide a thorough understanding of the application, but the application can also be implemented in other ways different from those described herein, and those skilled in the art can make similar generalizations without departing from the connotation of the application, therefore the application is not limited by the specific embodiments disclosed below.

[0024] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that is mutually exclusive with other embodiments.

[0025] This invention is described in detail with reference to the accompanying drawings. When detailing the embodiments of this invention, for ease of explanation, the cross-sectional views illustrating the device structure may be partially enlarged, not to scale. Furthermore, the accompanying drawings are merely examples and should not be construed as limiting the scope of protection of this invention. In actual fabrication, the three-dimensional spatial dimensions of length, width, and depth should be included.

[0026] Furthermore, it should be noted in the description of this invention that the terms "first," "second," or "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0027] Unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" in this invention should be interpreted broadly. For example, they can refer to fixed connections, detachable connections, or integral connections; similarly, they can refer to mechanical connections, electrical connections, or direct connections, or indirect connections through an intermediate medium, or internal connections between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0028] Example 1: As Figures 1 to 10 As shown, the rapid screening device for allergens in infant skincare products includes a reagent kit 300 and a placement mechanism 200 installed on an allergen detector 100. The placement mechanism 200 includes a moving component and a first adjusting component. The moving component includes a limiting box 233 and a friction block 238. The limiting box 233 is fixedly installed on the allergen detector 100, and a moving column 231 is slidably installed on the limiting box 233. The friction block 238 is slidably installed inside the limiting box 233.

[0029] During the entire process of inserting the reagent kit 300 into the allergen detector 100, the first adjustment component dynamically drives the friction block 238 to apply gradient pressure to the moving column 231 based on the insertion depth, adapting the reagent kit 300 to mechanically fit the allergen detector 100 at different stages.

[0030] It should be noted that the selection of skin care products: priority is given to simple ingredients, low sensitivity, baby-specific skin care products such as squalane, glycerol, and other basic moisturizing ingredients. Such skin care products are more valuable for testing, avoiding high-risk formulations containing fragrances, preservatives such as methylisothiazolinone, and plant extracts such as chamomile; extract samples: take 1-2 drops of the skin care product to be tested, dilute with normal saline at a ratio of 1:3, and then load into a clean test tube. Gently shake to avoid vigorous shaking to damage the ingredients, and use as a test sample; Prepare reagent kit 300: use allergen detection kit 300 containing pre-coated antibody swabs, nitrocellulose membranes and other components to ensure that the reagent kit is within the expiration date and is sealed properly; Instrument detection: immerse the reagent kit 300 swab in the sample liquid for 30 seconds, then place it in the allergen detector. During this process, the first adjustment assembly will continuously switch between driving modes, causing the friction block 238 to change the pressure on the moving column 231. This reduces the initial pressure to reduce the initial collision between the reagent kit 300 buckle and the guide rail inside the allergen detector 100, maintains moderate pressure in the stable stage to ensure that the NC membrane inside the reagent kit 300 is tightly attached to the binding pad, and adapts to the structure of the detection area of the allergen detector 100. The end stage reduces the pressure to buffer the contact between the end of the reagent kit 300 and the sensor inside the allergen detector 100, meeting the mechanical fitting and motion coordination requirements of the reagent kit 300 and the allergen detector 100 at different stages; Finally, start the detection, and the allergen detector 100 automatically completes the antigen-antibody reaction, washing and color development. The results are displayed after about 15 minutes.

[0031] As shown in Figures 6 to 8 The moving assembly further includes a first spring 232, a first magnetic block 234, a connecting block 236, and a first sliding rod 237. The first spring 232 is sleeved on the moving column 231, and the first spring 232 is fixedly connected with the limiting box 233. The first magnetic block 234 is slidingly installed on the limiting box 233, and the first magnetic block 234 is fixedly connected with the friction block 238. Two connecting blocks 236 are fixedly installed on both sides of the first magnetic block 234, and the two connecting blocks 236 are connected with the limiting box 233 through the second spring 235. Two first sliding rods 237 are slidingly connected with the two connecting blocks 236, and the two first sliding rods 237 are fixedly connected with the limiting box 233.

[0032] The first adjustment assembly includes a rack 241, a mounting plate 242, a first rotating shaft 243, a pushing column 244, a first bevel gear 245, a transmission disc 246, a second rotating shaft 247, a mounting seat 248, a grooved wheel 249, a third rotating shaft 2491, a second bevel gear 2492, a second magnetic block 2493, a mounting disc 2494, and a second gear 2495. The mounting plate 242 is fixedly mounted on the allergen detector 100, the first rotating shaft 243 and the second rotating shaft 247 are rotatably mounted on the mounting plate 242, the transmission disc 246 is fixedly mounted on the second rotating shaft 247, the transmission disc 246 is fixedly provided with the poking column 244, the grooved wheel 249 is fixedly mounted on the first rotating shaft 243, the grooved wheel 249 is matched with the transmission disc 246, the mounting seat 248 is fixedly mounted on the mounting plate 242, the third rotating shaft 2491 is rotatably mounted on the mounting seat 248, one end of the third rotating shaft 2491 is fixedly provided with the second bevel gear 2492, the other end of the third rotating shaft 2491 is fixedly provided with the second gear 2495, the first bevel gear 245 is fixedly mounted on the second rotating shaft 247, the first bevel gear 245 is engaged with the second bevel gear 2492, the rack 241 is engaged with the second gear 2495, the mounting disc 2494 is fixedly mounted on the first rotating shaft 243, and the mounting disc 2494 is fixedly provided with a plurality of second magnetic blocks 2493.

[0033] It should be noted that when the moving column 231 starts to move and the reagent box 300 enters the inside of the allergen detector 100, the rack 241 will move synchronously with the moving column 231, when the rack 241 moves, the rack 241 will make the second gear 2495 rotate, the rotation of the second gear 2495 will make the third rotating shaft 2491 rotate, the rotation of the third rotating shaft 2491 will make the second rotating shaft 247 rotate through the second bevel gear 2492 and the first bevel gear 245, so that the transmission disc 246 drives the poking column 244 to rotate, the poking column 244 rotates on the grooved wheel 249, so that the grooved wheel 249 rotates intermittently, the rotation of the grooved wheel 249 drives the first rotating shaft 243 to rotate, the first rotating shaft 243 drives the mounting disc 2494 to rotate, the rotation of the mounting disc 2494 drives the plurality of second magnetic blocks 2493 to rotate, the magnetic force of the plurality of second magnetic blocks 2493 is different, the second magnetic block 2493 repels the first magnetic block 234, the repulsive force of the second magnetic block 2493 pushes the first magnetic block 234 to move, so that the first magnetic block 234 drives the friction 238 to press and move the moving column 231, thereby limiting the moving speed of the moving column 231, that is, the speed of the reagent box 300 inserted into the allergen detector 100 is controlled.

[0034] The entire process of inserting the reagent kit 300 into the allergen detector 100 can be divided into three stages: an initial low-speed stage, a stable running stage, and an end buffering stage, and the four second magnetic blocks 2493 also correspondingly, the magnetic force of the second magnetic block 2493 on the first magnetic block 234 is the largest in the initial state, which will make the friction block 238 have a larger extrusion force to extrude the moving column 231, so that the moving speed of the moving column 231 will be very slow, and when moving to the stable running stage, it will be switched to another second magnetic block 2493, the effect of the second magnetic block 2493 on the first magnetic block 234 will be weakened, so that the moving speed of the moving column 231 will be faster, and continue to move stably, when reaching the last end buffering stage, it will also be switched to the remaining second magnetic block 2493, the remaining two second magnetic blocks 2493 will enhance the effect of the first magnetic block 234, so that the moving speed of the moving column 231 gradually decreases, so that the reagent kit 300 can be finally inserted into the allergen detector 100 stably, and no harm is caused.

[0035] Initial low-speed stage: smoothly push the reagent kit 300 to avoid violent collision of metal buckles or hard structures with the guide rail of the allergen detector 100; this stage protects the fragile buckles such as thin metal sheets and the contact area of the guide rail such as plastic guide rail from impact damage by controlling the initial kinetic energy, and ensures the integrity of the mechanical fit of the two.

[0036] Stable running stage: compared with the initial low-speed stage, the speed is increased and uniform motion is maintained to adapt to the synchronous displacement requirements of internal components such as NC membrane and binding pad of the reagent kit; the speed fluctuation in this stage is very small to ensure the uniformity of detection reactions such as sample chromatography and marker migration, and to avoid color deviation or signal loss caused by unstable speed.

[0037] End buffering stage: adopt deceleration mode to gradually reduce the pushing speed to prevent rigid impact of the end of the reagent kit 300 such as water absorption pad or buffer structure with the sensor photoelectric contact of the allergen detector 100; this stage absorbs the remaining kinetic energy through buffering design such as elastic limit block to protect the sensor contact from deformation and the reagent kit 300 structure from rupture, and ensures the stability at the end of detection.

[0038] As shown in Figure 2 and Figure 9 and Figure 10 The placing mechanism further includes a driving assembly, and the driving assembly includes a protective cover 211, a first connecting pipe 212, a hollow box 213, a storage box 214, an elbow pipe 215, a hollow disc 216, a driving box 217, a rotating pipe 218, a folding air bag 219, and a jet nozzle 2191. The storage box 214 is slidingly installed on the allergen detector 100, and the hollow box 213 is fixedly installed on the storage box 214; the hollow box 213 is fixedly connected with the moving column 231, and the hollow box 213 is fixedly connected with the first spring 232; and the protective cover 211 is fixedly installed on the hollow box 213.

[0039] It should be noted that by pulling the hollow box 213, the moving column 231 and the rack 241 can be moved, so that the rack 241 can be moved out of the inside of the allergen detector 100, and the reagent box 300 is stored in the inside of the storage box 214, so that the required reagent box 300 can be taken out for detection, and when the hollow box 213 is released, the moving column 231 and the rack 241 will return to the original state, and the reagent box 300 is inserted into the inside of the allergen detector 100 for detection.

[0040] As shown in Figure 2 and Figures 9 to 10 , the driving assembly further comprises a folding air bag 219 for connecting the hollow box 213 with the allergen detector 100; the folding air bag 219 is in communication with the hollow box 213, a first one-way valve is installed at the communication position of the folding air bag 219 and the hollow box 213, the first one-way valve allows gas to be discharged only from the inside of the folding air bag 219 to the inside of the hollow box 213, the folding air bag 219 is provided with an inflation nozzle, a second one-way valve is installed on the inflation nozzle, the second one-way valve allows external gas to enter only the folding air bag 219 through the inflation nozzle, and cannot be discharged from the folding air bag 219; the first connecting pipe 212 is fixedly installed on the hollow box 213, and the hollow disc 216 is fixedly installed on the first connecting pipe 212; the rotating pipe 218 is rotatably installed on the hollow disc 216, and the driving box 217 is fixedly installed on the rotating pipe 218; the elbow pipe 215 is fixedly installed on the driving box 217, and the air jet nozzle 2191 is threadedly connected to the elbow pipe 215.

[0041] As shown in Figures 2 to 4 , the placing mechanism 200 further comprises a clamping assembly, and the clamping assembly comprises a crown gear 221, a first fixed plate 222, a first gear 223, a fixed box 224, a first screw 225, a first threaded plate 226, an expansion air bag 227, and a connecting box 228; The first fixed plate 222 is fixedly installed on the storage box 214, and a plurality of fixed boxes 224 are fixedly installed in the inside of the first fixed plate 222; the first screw 225 is rotatably installed in the fixed box 224, one end of the first screw 225 is fixedly installed with the first gear 223, and the other end of the first screw 225 is threadedly connected with the first threaded plate 226 which is slidingly connected with the fixed box 224; the connecting box 228 is fixedly installed in the fixed box 224, and the expansion air bag 227 is fixedly installed on the connecting box 228; the crown gear 221 is engaged with the first gear 223, and the crown gear 221 is fixedly connected with the driving box 217.

[0042] It should be noted that the first fixed plate 222 has a placement slot in the center for placing the reagent box 300. When the reagent box 300 is placed inside the first fixed plate 222, the hollow box 213 is released. After the hollow box 213 is released, it will continuously drive the hollow box 213 to move closer to the allergen detector 100 due to the action of the first spring 232. During the movement of the hollow box 213, the hollow box 213 will also squeeze the folded air bag 219, causing the gas inside the folded air bag 219 to be transported to the inside of the hollow box 213. Then, the gas is transported to the inside of the drive box 217 through the first connecting pipe 212 and discharged from the bend pipe 215. Since there are four bend pipes 215 for spraying gas, the gas will cause the drive box 217 to rotate, so that the drive box 217 can make the crown gear 221 rotate. The rotation of the crown gear 221 will drive the first gear 223 to rotate, and the rotation of the first gear 223 will drive the first screw 225 to rotate, and the rotation of the first screw 225 will drive the first threaded plate 226 to move. The movement of the first threaded plate 226 will squeeze the gas in the fixed box 224. Since the fixed box 224 is in communication with the connecting box 228, and the connecting box 228 is in communication with the expansion air bag 227, the gas squeezed by the first threaded plate 226 can enter the expansion air bag 227 through the connecting box 228. In this way, the expansion air bag 227 will expand. Since the reagent box 300 has expansion air bags 227 in the upper, lower, left and right four directions, the four expansion air bags 227 will expand, which can make the reagent box 300 be at the center of the first fixed plate 222. This can facilitate the reagent box 300 to enter the allergen detector 100 accurately and avoid the problem of not being able to insert due to the position of the reagent box 300.

[0043] Moreover, the reagent box 300 is a disposable product and is mass-produced, so it cannot be guaranteed that the size of each reagent box 300 is exactly the same, and there will always be some errors. These errors often cause the reagent box 300 to be unable to be directly inserted into the inside of the allergen detector 100, affecting use. In addition, the first fixed plate 222 will be worn out during long-term use, which will also affect the accuracy of the placement of the reagent box 300 and affect the direct insertion of the reagent box 300 into the inside of the allergen detector 100. Therefore, the reagent box 300 is limited by the expansion air bag 227 at the center of the first fixed plate 222, which can better enable the reagent box 300 to be stably inserted into the allergen detector 100.

[0044] The jet nozzle 2191 can be replaced, and a plurality of jet nozzles 2191 are provided. The jet nozzles 2191 are away from the gas outlets of the bend pipes 215, and have different diameters. By controlling the diameter, the rotation speed of the drive box 217 can be adjusted, so as to change the limiting speed of the expansion air bag 227 on the reagent box 300, avoiding too fast or too slow limiting, which affects the accuracy of the limiting.

[0045] As Figure 2 And Figure 6 As shown in the second adjusting assembly further comprises a first moving plate 251, a fourth spring 252, a second slide rod 253, a second moving plate 254, a second fixed plate 255, a second screw rod 256; The first moving plate 251 is fixedly connected with the moving column 231 and the rack 241, and the second slide rod 253 is fixedly installed on the first moving plate 251; the second fixed plate 255 is fixedly installed on the allergen detector 100, and the second screw rod 256 is threadedly connected with the second fixed plate 255; the second moving plate 254 is slidably connected with the second slide rod 253, and the second moving plate 254 is threadedly connected with the second screw rod 256; the second moving plate 254 is connected with the first moving plate 251 through the fourth spring 252.

[0046] It should be noted that when the hollow box 213 is pulled, not only the force of the first spring 232 needs to be overcome, but also the force of the fourth spring 252 needs to be overcome, and by rotating the second screw rod 256, the second moving plate 254 will move, when the second moving plate 254 moves towards the second fixed plate 255, the second moving plate 254 will further pull the fourth spring 252, so the force of the fourth spring 252 needs to be overcome will be greater, relatively, when the moving column 231 releases, the moving column 231 moves the same path, and the moving speed will be faster, so not only the original initial low-speed stage, stable running stage and end buffer stage will not be damaged, but also the placing speed of the reagent box 300 can be further controlled according to the actual needs of the user, for example, when the workload is large and the amount of data to be screened is large, the speed can be accelerated for screening.

[0047] Working principle: when the reagent box 300 is inserted into the allergen detector 100 through the placing mechanism 200, the moving column 231 slides along the limiting box 233, synchronously driving the rack 241 to move; the rack 241 is engaged with the second gear 2495, driving the third rotating shaft 2491 to rotate, and through the engagement transmission of the second bevel gear 2492 and the first bevel gear 245, the second rotating shaft 247 is rotated; the second rotating shaft 247 drives the transmission disc 246 and the poking column 244 to rotate, the poking column 244 drives the groove wheel 249 to rotate intermittently, and then the first rotating shaft 243 and the mounting disc 2494 are synchronously rotated; a plurality of second magnetic blocks 2493 on the mounting disc 2494 rotate with it, and through the magnetic repulsion of the first magnetic block 234, the friction block 238 is dynamically pushed to extrude the moving column 231; the magnetic force difference of different second magnetic blocks 2493 makes the friction block 238 generate gradient pressure: the pressure is larger in the initial stage, the reagent box 300 insertion speed is reduced to reduce the collision of the buckle and the guide rail; the pressure is moderate in the stable stage, to ensure that the internal components of the reagent box are attached to the detection area; the pressure is reduced in the end stage, to buffer the contact of the reagent box and the sensor, and to realize the phased adaptation.

[0048] When the moving column 231 moves, the hollow box 213 compresses and folds the airbag 219. The gas enters the drive box 217 through the first connecting pipe 212 and is ejected from the nozzle 2191 of the curved pipe 215, driving the drive box 217 and the rotating pipe 218 to rotate around the hollow disk 216. The drive box 217 drives the crown gear 221 to rotate. The crown gear 221 meshes with the first gear 223, causing the first screw 225 to rotate and push the first threaded plate 226 to slide in the fixed box 224. The first threaded plate 226 compresses the gas in the fixed box 224, causing the expansion airbag 227 on the connecting box 228 to expand and center the reagent kit 300 from four directions, ensuring its accurate insertion into the allergen detector 100.

[0049] Rotating the second screw 256 can drive the second moving plate 254 to move along the second slide bar 253, changing the tension of the fourth spring 252; the change in the elastic force of the fourth spring 252 will adjust the resistance that the moving column 231 needs to overcome, while maintaining the phased speed mode, and controlling the overall insertion speed of the reagent kit 300 to adapt to different detection efficiency requirements.

[0050] The first spring 232 is sleeved on the moving column 231, providing a reset elastic force so that the moving column 231 drives the relevant components to reset after the test is completed; the connecting blocks 236 on both sides of the first magnetic block 234 slide along the first slide rod 237, and cooperate with the second spring 235 to buffer the magnetic force to ensure that the pressure adjustment of the friction block 238 is stable; the protective cover 211 protects the hollow box 213 and connecting parts, the storage box 214 provides a place for the reagent kit 300, and the one-way valve design of the folding airbag 219 ensures one-way gas flow and maintains driving stability.

[0051] Example 2: As Figures 1 to 10 As shown, while all other parts are the same as in Example 1, the difference between this example and Example 1 is that: The method of using the rapid screening device for allergens in infant and child skincare products is characterized by the following steps: Step 1: Reagent kit preloading and adaptive centering clamping: By pulling the hollow box 213 outward, the moving column 231 and rack 241 are simultaneously extended, placing the reagent kit 300 in the center placement slot of the first fixing plate 222; after releasing the hollow box 213, the folded airbag 219 is compressed to generate airflow, which drives the drive box 217 to rotate through the first connecting pipe 212, and is transmitted through the engagement of the crown gear 221 and the first gear 223, so that the first screw 225 pushes the first threaded plate 226 to compress the gas into the expansion airbag 227, and the four-way expansion airbag 227 expands synchronously to adapt to the size error and wear gap of the reagent kit 300, so as to dynamically center and fix the reagent kit 300. Step 2: Gradient insertion velocity and three-stage mechanical adaptation: After the hollow box 213 is released, the moving column 231 is moved back under the action of the composite elastic force, synchronously driving the rack 241 to drive the second gear 2495 to rotate, and the intermittent transmission through the first bevel gear 245, the second bevel gear 2492 and the groove wheel mechanism 249 makes the multiple magnetic force decreasing second magnetic blocks 2493 on the mounting disc 2494 act on the first magnetic block 234 in turn, controls the gradient pressure of the friction block 238 on the moving column 231, and realizes: Initial low-speed stage: collision of the high-pressure friction buffer kit 300 buckle with the guide rail; Stable running stage: uniform speed ensures that the NC film is tightly attached to the bonding pad; End buffer stage: deceleration prevents rigid impact of the kit 300 end on the sensor; Step three, speed fine-tuning and batch screening optimization: By rotating the second screw 256 to adjust the position of the second moving plate 254, the pre-tightening force of the fourth spring 252 is changed, the speed of the moving column 231 is controlled, and under the premise of not destroying the three-stage mechanical curve, the insertion process can be accelerated dynamically according to the screening amount demand; or replace the jet nozzle 2191 of different caliber to adjust the air flow intensity, change the limiting speed of the inflatable air bag 227, and adapt to the batch screening efficiency; Step four, automatic detection and result output: After the kit 300 is completely inserted, the allergen detector 100 automatically starts the antigen-antibody reaction, washing and color development program, and outputs the infant skin care product allergen screening result after about 15 minutes.

[0052] The above is only the preferred specific embodiment of the present application, but the protection scope of the present application is not limited thereto, any skilled person in the art can make equivalent replacement or change according to the technical scheme and the inventive concept of the present application within the technical range disclosed by the present application, which should be covered within the protection scope of the present application.

[0053] The preferred embodiments of the application disclosed above are only used to help explain the application. The preferred embodiments do not describe all the details, nor limit the application to the specific embodiments. Obviously, many modifications and changes can be made according to the content of the specification. The embodiments are selected and described in the specification in order to better explain the principles and practical applications of the application, so that those skilled in the art can well understand and utilize the application. The application is limited by the claims and their entire scope and equivalents.

Claims

1. A device for rapid screening of allergens in baby skin care products, comprising a reagent kit (300) and a placing mechanism (200) installed on an allergen detector (100), characterized in that: The placing mechanism (200) comprises a moving assembly and a first adjusting assembly; The moving assembly comprises: A limiting box (233) is fixedly installed on the allergen detector (100), and a moving column (231) is slidably installed on the limiting box (233); A friction block (238) is slidably installed in the limiting box (233); The first adjusting assembly dynamically drives the friction block (238) to apply gradient pressure to the moving column (231) based on the insertion depth in the complete stage of inserting the kit (300) into the allergen detector (100), and adapts the mechanical fit of the kit (300) and the allergen detector (100) in different stages.

2. The infant skin care allergen rapid screening device of claim 1, wherein, The moving assembly further comprises: A first spring (232) is sleeved on the moving column (231) and fixedly connected with the limiting box (233); A first magnetic block (234) is slidably installed on the limiting box (233) and fixedly connected with the friction block (238); Two connecting blocks (236) are fixedly installed on the two sides of the first magnetic block (234) respectively, and connected with the limiting box (233) through a second spring (235); Two first sliding rods (237) are slidably connected with the two connecting blocks (236) respectively and fixedly connected with the limiting box (233).

3. The infant skin care allergen rapid screening device of claim 2, wherein, The first adjusting assembly comprises: An installation plate (242) is fixedly installed on the allergen detector (100), and a first rotating shaft (243) and a second rotating shaft (247) are rotatably installed on the installation plate (242); A transmission disc (246) is fixedly installed on the second rotating shaft (247), and a dialing column (244) is fixedly installed on the transmission disc (246); A groove wheel (249) is fixedly installed on the first rotating shaft (243) and matched with the transmission disc (246).

4. The infant skin care allergen rapid screening device of claim 3, wherein, The first adjusting assembly further comprises: An installation seat (248) is fixedly installed on the installation plate (242); A third rotating shaft (2491) is rotatably installed on the installation seat (248), one end of the third rotating shaft (2491) is fixedly installed with a second bevel gear (2492), and the other end of the third rotating shaft (2491) is fixedly installed with a second gear (2495); A first bevel gear (245) is fixedly installed on the second rotating shaft (247) and engaged with the second bevel gear (2492); A rack (241) is engaged with the second gear (2495).

5. The infant skin care allergen rapid screening device of claim 4, wherein, The first adjusting assembly further comprises: An installation disc (2494) is fixedly installed on the first rotating shaft (243), and a plurality of second magnetic blocks (2493) are fixedly installed on the installation disc (2494).

6. The infant skin care allergen rapid screening device of claim 2, wherein, The placing mechanism (200) further comprises a driving assembly, and the driving assembly comprises: A storage box (214) is slidably installed on the allergen detector (100), and a hollow box (213) is fixedly installed on the storage box (214); the hollow box (213) is fixedly connected with the moving column (231) and the first spring (232); A protective cover (211) is fixedly installed on the hollow box (213).

7. The infant skin care allergen rapid screening device of claim 6, wherein, The driving assembly further comprises: A folding air bag (219) is used for connecting the hollow box (213) and the allergen detector (100). A first connecting pipe (212) is fixedly installed on the hollow box (213), and a hollow disc (216) is fixedly installed on the first connecting pipe (212); A rotating pipe (218) is rotatably installed on the hollow disc (216), and a driving box (217) is fixedly installed on the rotating pipe (218); A bent pipe (215) is fixedly installed on the driving box (217), and a jet nozzle (2191) is threadedly connected to the bent pipe (215).

8. The infant skin care allergen rapid screening device of claim 7, wherein, The placing mechanism (200) further comprises a clamping assembly, and the clamping assembly comprises: A first fixed plate (222) is fixedly installed on the storage box (214), and a plurality of fixed boxes (224) are fixedly installed in the first fixed plate (222); A first screw rod (225) is rotatably installed on the fixed box (224), one end of the first screw rod (225) is fixedly installed with a first gear (223), and the other end of the first screw rod (225) is threadedly connected with a first threaded plate (226) which is slidably connected with the fixed box (224); A connecting box (228) is fixedly installed in the fixed box (224), and an inflatable air bag (227) is fixedly installed on the connecting box (228); A crown gear (221) is in meshing connection with the first gear (223) and is fixedly connected with the driving box (217).

9. The infant skin care allergen rapid screening device of claim 4, wherein, The placing mechanism (200) further comprises a second adjusting assembly, and the second adjusting assembly comprises: A first moving plate (251) is fixedly connected with the moving column (231) and the rack (241), and a second sliding rod (253) is fixedly installed on the first moving plate (251); A second fixed plate (255) is fixedly installed on the allergen detector (100), and a second screw rod (256) is threadedly connected to the second fixed plate (255); A second moving plate (254) is slidably connected with the second sliding rod (253), is threadedly connected with the second screw rod (256), and is connected with the first moving plate (251) through a fourth spring (252).

10. The method of using the infant skin care allergen rapid screening device according to any one of claims 1-9, wherein, The method comprises the following steps: Step one, preloading: the hollow box (213) is pulled outward, the moving column (231) and the rack (241) are synchronously extended, the disposable reagent box (300) is gently placed on the center groove of the first fixed plate (222), after the hand is released, the folded air bag (219) is compressed, the airflow drives the crown gear (221) to rotate through the driving box (217), the four-way inflatable air bag (227) is synchronously inflated, and the reagent box (300) is automatically and accurately centered and clamped; Step two, gradient insertion: the moving column (231) is retracted under the combined action of the spring and the magnetic force; the four second magnetic blocks (2493) with decreasing magnetic force are sequentially close to the first magnetic block (234), the friction block (238) generates three-stage gradient pressure on the moving column (231), and the whole process of low-speed collision avoidance, uniform stable lamination and terminal buffer deceleration corresponding to the insertion of the reagent box (300) is realized; Step three, speed fine adjustment: the second screw rod (256) is rotated clockwise to increase the pre-tightening force of the fourth spring (252), so that the insertion speed of the reagent box (300) during the complete insertion into the allergen detector (100) is increased or decreased; Step four, automatic detection: after the reagent box (300) is completely in place, the allergen detector (100) automatically completes the antigen-antibody reaction, washing and color development process.

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