Intelligent management system for intracranial pressure

Abstract

The application relates to an intracranial pressure intelligent management system and belongs to the technical field of intracranial pressure monitoring devices, which comprises a closed cover and a pressure measuring rod, the pressure measuring rod comprises a pressure measuring section and a combined section, the pressure measuring section is provided with a pressure electrode set, a drainage main pipe, a plurality of pressure contact points and a plurality of drainage holes, the pressure electrode set and the drainage main pipe are fixed on an end surface connected with the combined section, the combined section comprises a plurality of head-tail spliced connecting thin blocks, the connecting thin block comprises an outer shell, an inflow interface and an electrode interface arranged at one end of the outer shell, and an outflow joint and an electrode joint arranged at the other end of the outer shell. The pressure monitoring and drainage process of the application adopts program control, is intelligently realized, no longer needs manual operation, realizes intelligent scientific management of intracranial pressure, meanwhile, a plurality of head-tail spliced connecting thin blocks are adopted to form the combined section, so that the length of the detection rod can be adjusted, the needs of different groups of people can be met, and the adaptability is obviously enhanced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of intracranial pressure monitoring devices, in particular to an intelligent intracranial pressure management system. BACKGROUND

[0002] An acute increase in intracranial pressure can cause serious consequences for patients. In the prior art, a self-tapping screw is used to measure intracranial pressure by being screwed into the intracranial space. This approach causes damage to the patient's meninges, leading to new pain, and also cannot form a good seal because the screw is connected to the skull, which can cause the overflow of cerebrospinal fluid and other body fluids when the intracranial pressure is high, resulting in contamination. To address this problem, some patents have adopted a negative pressure adsorption and wireless transmission method, which effectively solves the problem of damage to the patient's skull caused by threaded hard connections and the problem of wired entanglement.

[0003] The above-mentioned scheme still has the following problems:

[0004] 1. This scheme only monitors intracranial pressure, and once an abnormal increase in intracranial pressure is detected, medical personnel need to take emergency measures to perform a drainage procedure.

[0005] 2. Since this scheme occupies the channel connecting the intracranial space and the extracranial space, if a drainage procedure is required, the device needs to be removed and a drainage tube needs to be placed, which is a relatively complex operation.

[0006] 3. The pressure measuring rod of this scheme is not adjustable in length and cannot be detached from the housing, and therefore cannot be adapted to all patients.

[0007] Therefore, to solve the above problems, the present application improves the prior art to have more functions, maintain the intracranial pressure at a safe level without the need for additional operations, and significantly helps to improve the management level of intracranial pressure. SUMMARY

[0008] Therefore, the present application aims to provide an intelligent intracranial pressure management system that can measure intracranial pressure and perform a drainage procedure when the pressure is excessively high, so as to maintain the intracranial pressure at a reasonable level and solve the problem of no adjustment function in the prior art.

[0009] The present application is achieved by the following technical solutions:

[0010] The intelligent intracranial pressure management system comprises a closed cover and a pressure measuring rod.

[0011] The pressure measuring rod comprises a pressure measuring section and a combination section; the outer surface of the pressure measuring section is provided with a plurality of pressure contacts and a plurality of drainage holes, and a pressure electrode set and a drainage main pipe are fixedly arranged at one end of the pressure measuring section towards the combination section, the pressure electrode set is arranged in a plug-in state with the drainage main pipe; a plurality of the pressure contacts are connected to the pressure electrode set through wires, and a plurality of the drainage holes are connected to the drainage main pipe through pipelines;

[0012] The combination section comprises a plurality of connective thin blocks which can be connected head to tail, each of the connective thin blocks comprises an outer shell, one end of the outer shell is provided with an inflow interface and an electrode interface, and the other end of the outer shell is provided with an outflow joint and an electrode joint; the inflow interface is plug-in connectable with the drainage main pipe, and the inflow interface and the outflow joint of adjacent connective thin blocks are plug-in connectable to realize pipeline conduction; the electrode interface is plug-in connectable with the pressure electrode set, and the electrode interface and the electrode joint of adjacent connective thin blocks are plug-in connectable to realize circuit conduction;

[0013] The bottom of the closed cover is provided with a connecting seat, the connecting seat is provided with a drainage port and an electrical connector; the drainage port is plug-in connectable with the outflow joint of the combination section away from the pressure measuring section, and the drainage port is connected to the pipeline which penetrates out of the closed cover; the electrical connector is plug-in connectable with the electrode joint of the combination section away from the pressure measuring section;

[0014] The periphery of the closed cover is provided with a sealing ring, a sealing cavity is formed in the sealing ring, an air flow hole is arranged in the sealing cavity, the air flow hole extends along the closed cover and is connected to an air pressure adjusting device, and the air pressure adjusting device is used to reduce the air pressure in the sealing cavity to form a negative pressure, so that the closed cover is fixed to the brain of a patient;

[0015] The closed cover is covered with a transparent outer cover, a storage space is formed between the outer cover and the closed cover; a data processor, a micro liquid drainage pump and a hydrocephalus storage container are arranged in the storage space; the data processor is electrically connected with the electrical connector and is used to process the pressure signal transmitted by the electrical connector; the input end of the micro liquid drainage pump is connected with the pipeline which penetrates out of the closed cover at the drainage port, and the output end of the micro liquid drainage pump is connected with the hydrocephalus storage container, and is used to suck intracranial hydrocephalus out to the hydrocephalus storage container;

[0016] The outer cover is provided with a display on the outside, and is provided with an electrical socket on the inside; an electrical plug is arranged on the data processor and is plug-in connectable with the electrical socket; the electrical socket is electrically connected with the display, and the display is used to display the intracranial pressure information processed by the data processor;

[0017] Further comprising an external operator, the operator is in wireless communication connection with the data processor, and is used for controlling the pressure signal processing logic of the data processor, the start-stop of the micro liquid drainage pump and the negative pressure intensity of the air pressure adjusting device.

[0018] Further, the air pressure adjusting device is arranged in the storage space, and is protected by the outer cover.

[0019] Further, the top of the outer cover is provided with a handle, which is integrally formed with the outer cover or detachably connected with the outer cover.

[0020] Further, the pressure measuring section comprises a conical head and a cylindrical pipe integrally formed with the conical head; the conical head is a thin-shell cavity body, a plurality of pressure contacts extend out of the cavity of the conical head through through-holes formed on the thin shell of the conical head, and a plurality of drainage holes are arranged through the thin shell of the conical head; the cylindrical pipe is provided with a wire tube and a pipeline tube; the wire tube is used for accommodating wires connected with the pressure contact and the pressure electrode set, and the pipeline tube is used for accommodating pipelines connected with the drainage hole and the drainage main pipe; the wire tube is in communication with the pressure electrode set, and the pipeline tube is in communication with the drainage main pipe.

[0021] Further, the start-stop of the micro liquid drainage pump is automatically controlled by the data processor; the data processor is provided with a preset intracranial pressure threshold range; when the processed intracranial pressure signal is higher than the upper limit of the threshold range, the data processor outputs a start signal to the micro liquid drainage pump; when the processed intracranial pressure signal is lower than the lower limit of the threshold range, the data processor outputs a stop signal to the micro liquid drainage pump.

[0022] Further, the shell of the connecting thin block is made of medical-grade polyether ether ketone or medical-grade polypropylene material, and the inner wall of the shell is provided with a reinforcing rib.

[0023] Further, the pressure contact is made of medical-grade platinum-iridium alloy or medical-grade stainless steel material, and the outer surface of the pressure contact is provided with a polishing layer.

[0024] The present application has the following beneficial effects:

[0025] The present application can monitor intracranial pressure and automatically drain cerebrospinal fluid in appropriate cases, so as to realize automatic adjustment of intracranial pressure, and through program control, the whole process is accurate and reliable, so as to realize the design goal of accurate intelligent management of intracranial pressure; at the same time, since external drainage is not needed, the cumbersome drainage operation is reduced, the operation risk and nursing cost are reduced, and the patient is extremely friendly; in addition, through wireless communication, the wire winding is reduced, and the inconvenience brought by wired transmission is avoided, in particular, the present application adopts a plurality of head-tail spliced connecting thin blocks to form a combined section, so as to realize the adjustment of the length of the detection rod, and adapt to the needs of different people. BRIEF DESCRIPTION OF DRAWINGS

[0026] Figure 1 It is a front view of the present application;

[0027] Figure 2 It is a sectional view of the closure cover of the present application;

[0028] Figure 3 It is a front view of the detection rod of the present application;

[0029] Figure 4 It is a sectional view of the combined section;

[0030] Figure 5 It is a sectional view of the pressure measuring section;

[0031] Figure 6 It is a sectional view of the connecting thin block.

[0032] BRIEF DESCRIPTION OF DRAWINGS:

[0033] 1-closure cover; 2-pressure measuring rod; 3-pressure measuring section; 4-combined section; 5-pressure electrode set; 6-drainage main pipe; 7-pressure contact; 8-drainage hole; 9-connecting thin block; 91-outer shell; 92-inflow interface; 93-electrode interface; 94-outflow joint; 95-electrode joint; 10-connection seat; 11-drainage port; 12-electrical joint; 13-sealing ring; 14-sealing cavity; 15-air flow hole; 16-air pressure adjusting device; 17-outer cover; 18-storage space; 19-data processor; 20-micro liquid drainage pump; 21-cerebrospinal fluid storage container; 22-display; 23-electrical socket; 24-electrical plug; 25-holding handle; 26-conical head; 27-cylindrical tube; 28-wire; 29-pipeline; 30-wire tube; 31-pipeline tube; 32-operator. DETAILED DESCRIPTION

[0034] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. The components of the embodiments of the present invention described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0035] Therefore, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the invention without inventive effort are within the scope of protection of the invention.

[0036] like Figures 1-6 As shown, one embodiment of the present invention provides an intelligent intracranial pressure management system, including a closed cover 1 and a pressure measuring rod 2. The pressure measuring rod 2 includes a pressure measuring section 3 and a combined section 4. The pressure measuring section 3 is provided with a pressure electrode set 5, a drainage manifold 6, multiple pressure contacts 7, and multiple drainage holes 8. The multiple pressure contacts 7 are distributed on the outer surface of the pressure measuring section 3 and are concentrated at the pressure electrode set 5 through wires 28. The multiple drainage holes 8 are distributed on the outer surface of the pressure measuring section 3 and converge to the drainage manifold 6 through pipes 29. The pressure electrode set 5 and the drainage manifold 6 are fixed to the end face connected to the combined section 4 and are spaced apart to form an interlocking state. The combined section 4 includes multiple connecting thin blocks 9 spliced ​​end to end. By combining the multiple connecting thin blocks 9, an arbitrary length can be formed to adapt to different patients. In addition, it also forms a detachable structure for easy assembly and use. The connecting thin block 9 includes a housing 91 and an inflow port 92 and an electrode port 93 located at one end of the housing 91, and an outflow connector 94 and an electrode connector 95 located at the other end of the housing 91. The inflow port 92 is inserted and connected to the drainage main pipe 6, and the inflow port 92 and the outflow connector 94 can also be inserted and connected to achieve quick replacement. At the same time, the electrode port 93 is inserted and connected to the pressure electrode set 5, and the electrode port 93 and the electrode connector 95 are inserted and connected to achieve quick replacement. The bottom of the sealing cover 1 is provided with a connecting seat 10. The connecting seat 10 is provided with a drainage port 11 that is inserted into the outflow connector 94 and an electrical connector 12 that is inserted into the electrode connector 95. The drainage port 11 passes through the sealing cover 1 through the pipe 29 and communicates with the outside to achieve drainage. The electrical connector 12 passes through the cover through the wire 28 and communicates with the outside to achieve pressure signal transmission.

[0037] As an improvement to this embodiment, a sealing ring 13 is provided around the periphery of the sealing cover 1, a sealing cavity 14 is provided inside the sealing ring 13, and an airflow hole 15 is provided inside the sealing cavity 14. The airflow hole 15 extends through the sealing cover 1 to the air pressure regulating device 16. The air pressure regulating device 16 reduces the air pressure inside the sealing cavity 14 to form a negative pressure, so that the sealing cover 1 is fixed to the brain and the corresponding operation is performed.

[0038] As an improvement of the embodiment, a transparent outer cover 17 is further included, which covers the outside of the closure 1 to form a closed storage space 18, and the air pressure adjusting device 16 (such as a micro air pump) is arranged in the storage space 18 to form necessary protection. The transparent outer cover 17 is also convenient for observing the necessary facilities in the space.

[0039] As an improvement of the embodiment, a data processor 19 is further arranged in the storage space 18, which is in electrical communication with the electrical connector 12, and the data processor 19 processes the electrical signals obtained by the electrical connector 12 to realize the measurement of the intracranial pressure.

[0040] As an improvement of the embodiment, a micro liquid discharge pump 20 and a cerebral fluid storage container 21 are further arranged in the storage space 18, the micro liquid discharge pump 20 is in communication with the drainage port 11, and the micro liquid discharge pump 20 forms a negative pressure to suck out the cerebral fluid and enter the cerebral fluid storage container 21 to realize the storage.

[0041] As an improvement of the embodiment, a display 22 for pressure display is arranged on the outside of the outer cover 17, an electrical socket 23 is arranged on the inside of the outer cover 17, the data processor 19 is provided with an electrical plug 24 which is inserted into the electrical socket 23, and the electrical socket 23 is in electrical communication with the display 22. When used, the electrical plug 24 is inserted to make the display 22 in communication with the data processor 19, the pressure information processed by the data processor 19 is displayed, and the medical staff can timely understand the intracranial pressure of the patient.

[0042] In use, first adjust the length of the detection rod (i.e. the pressure measuring rod 2) to the appropriate length: remove the detection rod (i.e. the pressure measuring rod 2) from the connecting seat 10, then place the detection rod (i.e. the pressure measuring rod 2) into the brain through the wound, and observe whether it reaches the cerebrospinal fluid detection area. If it is found that the detection rod (i.e. the pressure measuring rod 2) is too long, then remove some of the connecting thin blocks 9, and then observe and adjust again until it is just right for detection. Similarly, if it is found to be too short, then add connecting thin blocks 9, and then observe and adjust again until it is just right. When the length of the detection rod (i.e. the pressure measuring rod 2) is adjusted, insert it into the connecting seat 10, and insert the electrical plug 24 into the electrical socket 23 to form electrical communication. Then cover the closure cap 1 around the patient's wound, and fix it by negative pressure. At this time, the detection rod (i.e. the pressure measuring rod 2) enters the cerebrospinal fluid in the brain ventricle, and the multiple pressure contacts 7 contact the cerebrospinal fluid and are concentrated in the pressure electrode set 5 through the wires 28. Then, through the electrode interface 93, the electrode connector 95, and the electrical connector 12, the information is finally fed back to the data processor 19, realizing the feedback of measurement information, and thus realizing real-time monitoring of pressure information. When the pressure is found to be higher than the set value, the drainage operation is started. At this time, the miniature drainage pump 20 is started, the pipeline 29 is in a negative pressure state, the cerebrospinal fluid is sucked out, and finally enters the cerebrospinal fluid storage container 21 for storage. When the appropriate range is reached, the drainage work stops, thus realizing intelligent drainage.

[0043] The above-mentioned pressure monitoring and drainage process is fully controlled by a program, and is intelligently realized, so that manual operation is no longer needed, and intelligent scientific management of intracranial pressure is realized. At the same time, since external drainage is not needed, the cumbersome drainage operation is reduced, and the operation risk and nursing cost are reduced. In addition, through wireless communication, the entanglement of wires is reduced, and the inconvenience caused by wired transmission is avoided. In particular, the connecting thin blocks 9 are spliced together to form the combined section 4, so that the length of the detection rod (i.e. the pressure measuring rod 2) can be adjusted, and the needs of different people are met, and the adaptability is significantly enhanced.

[0044] As a further improvement of the present embodiment, the top of the outer cover 17 is provided with a lifting handle 25 which is integrally formed with or detachably connected to the outer cover 91, so that disassembly is more convenient.

[0045] As a further improvement of the embodiment, the pressure measuring section 3 comprises a conical head 26 and a cylindrical tube 27 integrally arranged with the conical head 26, the conical head 26 is a thin shell cavity, a plurality of pressure contacts 7 extend out of the cavity through through holes arranged on the thin shell cavity, a plurality of drainage holes 8 are arranged through the thin shell cavity, and any pressure contact 7 is connected with a wire 28, and any drainage hole 8 is connected with a pipeline 29, so as to realize the measurement of multiple points and the drainage of multiple points, so that the measurement is more accurate and the drainage is more balanced, the cylindrical tube 27 is provided with a wire tube 30 for collecting the wires 28 and a pipeline tube 31 for collecting the pipelines 29, the wire tube 30 is in communication with the pressure electrode set 5, and the pipeline tube 31 is in communication with the drainage main pipe 6, so as to facilitate the standardization and constraint of the pressure line and the drainage pipe.

[0046] As a further improvement of the embodiment, an operator 32 for adjusting pressure is arranged outside, and the operator 32 communicates with the data processor 19 through wireless transmission. Through the wireless communication between the operator 32 and the data processor 19, real-time control of the entire device can be realized, different patient needs can be met, and individualized design can be realized.

[0047] The embodiment significantly improves the experience of the patient and enhances the confidence of the patient due to the non-invasive fixation by negative pressure, and is also beneficial to the stability of the intracranial pressure of the patient and the rapid recovery of the patient.

[0048] According to the above content, a specific embodiment is provided:

[0049] 1. Pressure measuring rod assembly

[0050] The pressure measuring section 3: the conical head 26 is made of medical grade liquid silicone with Shore A hardness of 30-40, the thin shell cavity has a wall thickness of 0.8 mm, the tip diameter is 2 mm, the base diameter is 5 mm, and the length is 12 mm, which can reduce the mechanical stimulation to the intracranial brain tissue; the cylindrical tube 27 is made of medical grade titanium alloy (TC4 material), with an outer diameter of 4 mm, an inner diameter of 3 mm, and a length of 3 cm, and the tube wall roughness Ra≤0.8 μm to avoid scratching the intracranial blood vessels.

[0051] The pressure contact 7: a series of piezoresistive pressure sensors are selected There are 8 pressure contacts 7, which are evenly distributed on the outer surface of the conical head 26 (2-3 at 3 mm, 6 mm, and 9 mm from the tip), with a measurement range of 0-500 mmH2O, an accuracy of ±1.5 mmH2O, and a response time of ≤10 ms; each pressure contact 7 is connected to the wire tube 30 through a φ0.3 mm medical shielding wire 28 (the insulation layer is polytetrafluoroethylene), the wire tube 30 is a φ1 mm polytetrafluoroethylene hose, and 8 shielding wires 28 are built-in to avoid signal interference.

[0052] Drainage hole 8: 4 drainage holes 8 are symmetrically distributed within 3 mm of the bottom of the tapered head 26, with a hole diameter of 1.5 mm and a hole spacing of 90°. Each drainage hole 8 is connected to the pipeline tube 31 through a medical silicone tube 29 (wall thickness 0.3 mm) with a diameter of φ1.2 mm. The pipeline tube 31 is a φ2 mm polyvinyl chloride hard tube, which ensures the stability of the cerebrospinal fluid drainage flow rate.

[0053] Pressure electrode set 5 and drainage main pipe 6: The pressure electrode set 5 is a circular medical-grade ceramic electrode plate with a diameter of 4 mm, which is provided with 8 gold-plated terminals (corresponding to 8 pressure contacts 7) with a terminal spacing of 0.5 mm. The drainage main pipe 6 is a φ3 mm polyvinyl chloride hard tube with a length of 15 mm, which is inserted into the pipeline tube 31 through a medical-grade ABS plastic joint with an insertion depth of 3 mm, and is leak-proof with an O-shaped silicone sealing ring (diameter 3 mm, wire diameter 0.5 mm).

[0054] Combination section 4: The connecting thin block 9 is made of medical-grade ABS plastic (ISO10993-1 biocompatibility certification), each with a length of 2 cm, a width of 5 mm, and a thickness of 3 mm. The inflow interface 92 is a φ3 mm internal threaded interface (M3x0.5), the outflow joint 94 is a φ3 mm external threaded joint (M3x0.5), the electrode interface 93 and the electrode joint 95 are gold-plated pins (diameter 0.8 mm, length 5 mm) with a contact resistance of ≤50 mΩ after insertion. According to the depth of the hematoma of 5 cm, 2 connecting thin blocks 9 (total length 4 cm) are selected in this embodiment, which are spliced with the pressure measuring section 3 (cylindrical tube 27 long 3 cm) to ensure that the tapered head 26 can accurately reach the 3 key monitoring areas (center of hematoma, edge of hematoma, normal brain tissue) around the hematoma.

[0055] 2. Enclosure 1 and outer cover assembly

[0056] Enclosure 1: Made of transparent medical-grade polycarbonate (PC), with a diameter of 15 cm and a height of 8 cm, and an inner wall smoothness of Ra≤0.4 μm. The connecting seat 10 is a cylindrical protrusion with a diameter of 6 mm (adapted to the combination section 4 of the pressure measuring rod 2), and the drainage port 11 is a φ3 mm polyvinyl chloride interface with a built-in silicone sealing ring (Shore A hardness 50) with a sealing pressure of ≥0.1 MPa after insertion with the outflow joint 94. The electrical joint 12 is an 8-core gold-plated terminal (corresponding to the pressure electrode set 5) with a terminal spacing of 1 mm, which is connected to the shielded wire 28 with a diameter of φ5 mm.

[0057] Sealing ring 13: made of medical sponge (density 30 kg / m³) wrapped around a medical silica gel strip (cross section 2 mm x 3 mm), with an inner diameter of 12 cm, an outer diameter of 15 cm, and a thickness of 5 mm; the sealing cavity 14 has an inner diameter of 13 cm, an outer diameter of 14 cm, and a height of 3 mm, and the airflow hole 15 is a φ2 mm polyvinyl chloride pipe, one end of which is connected to the sealing cavity 14, and the other end is connected to the air pressure adjusting device 16 through a quick connector.

[0058] Outer cover 17: transparent medical-grade PC material, diameter 16 cm, height 12 cm, connected to the closure cover 1 through a buckle (buckle depth 3 mm, matched with a silica gel sealing strip), forming a sealed storage space 18 with a volume of about 1.5 L; the handle 25 is an integrated injection molded PC structure, with a length of 10 cm and a width of 3 cm, capable of bearing ≥5 kg, making it easy to hold during transportation.

[0059] 3. Functional components

[0060] Air pressure adjusting device 16: Festo VMPA1-M1H-M-PI micro air pump (i.e. air pressure adjusting device 16) is selected, with an air pressure adjustment range of -50~50 mmH2O, an adjustment accuracy of ±2 mmH2O, and a flow rate of 50 mL / min. It is connected to the airflow hole 15 through a φ2 mm silica gel pipeline 29, and the air pressure in the sealing cavity 14 can be dynamically adjusted according to the intracranial pressure data (e.g. when the intracranial pressure is too high, the air pressure in the sealing cavity 14 is reduced to -10~-20 mmH2O to assist in pressure reduction).

[0061] Data processor 19: STM32F407ZGT6 single-chip microcomputer (i.e. data processor 19) is used, with a main frequency of 168 MHz, a built-in 1 MB Flash memory, and support for 16-channel 12-bit ADC sampling; connected to the electrical connector 12 through an 8-core shielded wire 28, with a sampling frequency of 10 Hz, capable of processing the raw data of the 8 pressure touch points 7 in real time (removing drift and filtering), calculating the average intracranial pressure, maximum pressure difference, and other parameters; equipped with a USB interface (for data export) and a wireless module (Bluetooth 5.0 + Wi-Fi 802.11b / g / n, dual-mode communication backup).

[0062] Mini drainage pump 20: Longer BT100-1F peristaltic pump (i.e. mini drainage pump 20) is selected, with a flow rate adjustment range of 0.01~5 mL / min and an accuracy of ±2%, connected to the drainage port 11 and the cerebrospinal fluid storage container 21 through a φ3 mm medical silica gel pipeline 29; the pump head is made of medical-grade stainless steel, capable of withstanding 121°C high-temperature sterilization, and avoiding cross-infection.

[0063] Cerebrospinal fluid storage container 21: 50 mL transparent polyvinyl chloride (PVC) bottle (i.e., cerebrospinal fluid storage container 21), with scale (minimum graduation value 1 mL) and screw seal cap (with built-in nitrile rubber gasket), bottle opening connected to silicone tubing 29 of micro-liquid drainage pump 20 through a Luer connector, allowing real-time observation of drainage volume, and audible and visual prompts for replacement when full.

[0064] Display 22 and operator 32: Display 22 is a 2.4-inch OLED screen (resolution 320 x 240) fixed to the outside of outer cover 17, displaying real-time intracranial pressure value (unit mmH2O), pressure curve (trend for nearly 1 h), micro-liquid drainage pump 20 flow, sealed cavity 14 air pressure, and component working status; Operator 32 is an iPad mini 6 (iOS 16 system) installed with customized management software, supporting wireless connection to data processor 19 (Bluetooth communication distance ≤10 m, Wi-Fi communication distance ≤30 m), allowing setting of intracranial pressure threshold (e.g., alarm upper limit 200 mmH2O, lower limit 70 mmH2O), one-key adjustment of micro-liquid drainage pump 20 flow (0.1 mL / min step) and air pressure value, and automatic storage of pressure data (recorded once every 5 min, exportable in Excel format).

[0065] Power supply component: 12V / 10Ah lithium battery (using 18650 battery cell, capacity 10000mAh) built-in storage space 18, supporting fast charging (2h full), and continuous use time ≥8h; AC 220V charging interface (with anti-mis-touch protection) allows continuous power supply in the patient room or use without power supply for patient transfer.

[0066] The implementation process of the pressure monitoring of the present application can be implemented by existing technologies, which is not the main innovation point of the present application. However, in order to further illustrate the present application and enable ordinary skilled persons to implement it, the present embodiment specifically provides the whole process of pressure monitoring of the intracranial pressure intelligent management system:

[0067] I. Whole process of pressure monitoring

[0068] The whole process of pressure monitoring is carried out around "signal collection-signal transmission-data processing-parameter calculation-data presentation and storage", involving core components such as pressure measuring rod 2, closed cover 1, data processor 19, display 22, etc., and the specific process is as follows:

[0069] 1. Pressure signal collection: multiple contact points contact cerebrospinal fluid to generate original signals

[0070] Contact point contact and signal generation: in the pressure measuring section 3 of the pressure measuring rod 2, the outer surface of the conical head 26 is uniformly distributed with 8 series of pressure resistance type pressure contacts 7 (2-3 at 3 mm, 6 mm, 9 mm from the cone tip), which directly contact the cerebrospinal fluid when the pressure measuring rod 2 is inserted into the brain ventricle through the wound.

[0071] Due to the piezoresistive sensor characteristics, cerebrospinal fluid pressure will cause the internal resistance of the contact to change, thereby converting the pressure physical quantity into an analog electrical signal (measurement range 0-500 mmH2O, accuracy ±1.5 mmH2O, response time ≤10 ms, ensuring real-time capture of pressure changes).

[0072] Signal preliminary convergence: Each pressure contact 7 transmits the analog electrical signal to the wire tube 30 in the cylindrical tube 27 through a φ0.3 mm medical shielding wire 28 (insulation layer is polytetrafluoroethylene, prevents signal interference), and finally converges to the pressure electrode set 5 of the pressure measuring section 3 (a circular medical-grade ceramic electrode plate with a diameter of 4 mm, provided with 8 gold-plated terminals corresponding to 8 contacts, ensuring lossless transmission of signals).

[0073] 2. Signal transmission: Multiple components work together to ensure signal transmission without interference

[0074] Internal component connection transmission: The signal of the pressure electrode set 5 is connected to the electrode connector 95 (contact resistance ≤50 mΩ after insertion, reducing signal attenuation) through the electrode interface 93 (gold-plated pin, diameter 0.8 mm) of the combination section 4, and transmitted to the electrical connector 12 (8-core gold-plated terminal, corresponding to the 8 terminals of the pressure electrode set 5) in the connecting seat 10 at the bottom of the closed cover 1.

[0075] Final data processor: The electrical connector 12 passes through the φ5 mm shielding wire 28 of the closed cover 1, and inputs the analog electrical signal to the data processor 19 (STM32F407ZGT6 single-chip microcomputer, main frequency 168 MHz, supporting 16-channel 12-bit ADC sampling, meeting the needs of multi-contact signal parallel processing) in the storage space 18.

[0076] 3. Data preprocessing: Eliminate interference and ensure the validity of raw data

[0077] The data processor 19 first preprocesses the collected analog electrical signal, the core goal of which is to remove noise and baseline drift, and the specification clearly states "remove drift and filter processing". The specific operation is as follows:

[0078] Analog signal to digital signal (ADC sampling): The data processor is equipped with a 12-bit ADC module, which converts the analog electrical signals of the 8 contacts into digital signals at a sampling frequency of 10 Hz (matching the response time of the pressure contact 7, avoiding signal missing or redundancy), laying a foundation for subsequent processing.

[0079] Baseline drift correction: In cerebrospinal fluid pressure monitoring, sensor temperature changes and slight contact displacements can cause the signal baseline to slowly drift (non-real pressure changes). This drift is eliminated by an algorithm, and the common way is "linear trend removal" (calculate the linear trend of the signal in a period of time and subtract it, so that the baseline returns to a stable value), to ensure that the pressure data reflects the true intracranial pressure.

[0080] Noise filtering: There are interference signals (high frequency or random noise) such as electrode contact noise and device power supply noise in the monitoring environment. By filtering algorithm, noise is filtered and effective pressure signal is preserved (the specification does not specify the type of filtering, but combined with the characteristics of physiological signals, it is speculated that Butterworth low-pass filtering or moving average filtering is used: the former can smooth high-frequency noise, and the latter can reduce random noise by taking the average of N consecutive sampling points, while ensuring signal response speed).

[0081] 4. Feature parameter calculation: Extract key pressure indicators

[0082] The preprocessed digital signal needs to be further calculated for core monitoring parameters, and it is clearly required to "calculate average intracranial pressure, maximum pressure difference and other parameters". The specific calculation logic is as follows:

[0083] Average intracranial pressure calculation: Considering that 8 pressure contacts are distributed in different areas of the brain (such as the center of the hematoma, the edge of the hematoma, and normal brain tissue), multi-contact data needs to be fused to avoid single-point errors. The "weighted average algorithm" is used:

[0084] Assign weights to the pressure values of each contact (such as higher weights for hematoma center contacts, as the pressure in this area can better reflect key changes in the patient's condition; or assign values based on contact signal quality, with higher weights for contacts with higher signal stability);

[0085] Calculate the weighted pressure mean value as the representative value of the current intracranial pressure (to avoid monitoring deviations caused by single contact failure and improve accuracy).

[0086] Maximum pressure difference calculation: Traverse the real-time pressure values of the 8 contacts and calculate the difference between the "maximum value - minimum value", which reflects the pressure distribution difference between different areas of the brain (such as the pressure difference between the hematoma and normal brain tissue, which can help judge the intracranial pressure balance and provide a basis for subsequent drainage decisions).

[0087] 5. Data presentation and storage: visualization and traceability

[0088] Real-time visual display: The data processor 19 transmits the parameters such as average intracranial pressure and maximum pressure difference to the display 22 (2.4-inch OLED screen, resolution 320x240) outside the cover 17 through the connection of the electrical socket 23 and the electrical plug 24, and displays "real-time pressure value (unit mmH2O), pressure curve (trend in the past 1h)", which facilitates the medical staff to intuitively master the dynamic changes of intracranial pressure.

[0089] Data storage and traceability: The operator 32 (such as an iPad mini 6) stores the pressure data (including raw data, average pressure, and maximum pressure difference) at a frequency of "once every 5 minutes" through wireless communication with the data processor 19 via Bluetooth / Wi-Fi, and supports Excel format export, which facilitates subsequent disease analysis and treatment effect traceability (the specification clearly mentions "automatic storage of pressure data" and "Excel format export").

[0090] II. Summary of core algorithms involved in pressure monitoring

[0091] In combination with the monitoring content and monitoring logic, the algorithms involved in the whole process of pressure monitoring can be divided into four categories, as shown in the following table:

[0092] Algorithm category Specific algorithm example Function Associated content Data preprocessing algorithm Baseline drift correction (linear trend removal) Eliminate non-real pressure changes caused by sensor drift, ensure data accuracy "Remove drift" De-noising algorithm Noise filtering (Butterworth low-pass / moving average) Filter high-frequency, random noise, retain valid pressure signal "Filtering process" Multi-source data fusion algorithm Weighted average algorithm Fuse 8 pressure contact data, calculate average intracranial pressure, avoid single point error "Calculate average intracranial pressure" Feature parameter calculation algorithm Difference calculation algorithm Calculate the difference between the maximum and minimum values of the pressure of the 8 contacts, reflect the difference in intracranial pressure distribution "Calculate maximum pressure difference" Data storage and trend generation algorithm Time series sliding window algorithm Generate pressure trend curve according to 1h time window, store data according to 5min interval, support visualization and traceability "Pressure curve (1h trend)" "Record once every 5min"

[0093] In addition, to ensure monitoring stability, there may be an "outlier detection algorithm" (such as the 3σ criterion): when a contact pressure value exceeds the range of "mean ± 3 times standard deviation", it is determined as an outlier (such as contact failure), and the data is automatically excluded or marked for alarm to avoid affecting the overall monitoring results (although not explicitly mentioned here, it is a necessary guarantee logic for multi-contact monitoring).

[0094] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application and are not limiting. Although the present application has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or replaced equivalently without departing from the purpose and scope of the present application, and all should be covered in the scope of the claims of the present application.

Claims

1. An intracranial pressure intelligent management system, characterized in that, The pressure measuring device comprises a closed cover and a pressure measuring rod; The pressure measuring rod comprises a pressure measuring section and a combination section; the outer surface of the pressure measuring section is provided with a plurality of pressure contacts and a plurality of drainage holes; a pressure electrode set is fixedly arranged at one end of the pressure measuring section towards the combination section; the pressure electrode set is arranged in a plug-in adaptive state with the drainage main pipe; the plurality of pressure contacts are connected to the pressure electrode set through a wire; the plurality of drainage holes are connected to the drainage main pipe through a pipeline; The combination section comprises a plurality of connective thin blocks which can be connected head to tail; each connective thin block comprises an outer shell, one end of the outer shell is provided with an inflow interface and an electrode interface, and the other end of the outer shell is provided with an outflow joint and an electrode joint; the inflow interface is plug-in connectable with the drainage main pipe; the inflow interface and the outflow joint of adjacent connective thin blocks are plug-in connectable to realize pipeline conduction; the electrode interface is plug-in connectable with the pressure electrode set; the electrode interface and the electrode joint of adjacent connective thin blocks are plug-in connectable to realize circuit conduction; The bottom of the closed cover is provided with a connecting seat; the connecting seat is provided with a drainage port and an electrical connector; the drainage port is plug-in connectable with the outflow joint of the combination section away from the pressure measuring section; the drainage port is connected to the pipeline which penetrates out of the closed cover; the electrical connector is plug-in connectable with the electrode joint of the combination section away from the pressure measuring section; The periphery of the closed cover is provided with a sealing ring; a sealing cavity is formed in the sealing ring; an air flow hole is arranged in the sealing cavity; the air flow hole extends along the closed cover and is connected to a gas pressure adjusting device; the gas pressure adjusting device is used to reduce the air pressure in the sealing cavity to form a negative pressure, so that the closed cover is fixed to the brain of a patient; A transparent outer cover is arranged on the outside of the closed cover; a storage space is formed between the outer cover and the closed cover; a data processor, a micro liquid drainage pump and a hydrocephalus storage container are arranged in the storage space; the data processor is electrically connected with the electrical connector and is used to process the pressure signal transmitted by the electrical connector; the input end of the micro liquid drainage pump is connected to the pipeline which penetrates out of the closed cover; the output end of the micro liquid drainage pump is connected to the hydrocephalus storage container, and is used to suck intracranial hydrocephalus out to the hydrocephalus storage container; An external display is arranged on the outside of the outer cover; an electrical socket is arranged in the inside of the outer cover; an electrical plug is arranged on the data processor and is plug-in connectable with the electrical socket; the electrical socket is electrically connected with the display; the display is used to display the intracranial pressure information processed by the data processor; An external operator is further arranged; the operator is wirelessly connected with the data processor and is used to control the pressure signal processing logic of the data processor, the start and stop of the micro liquid drainage pump and the negative pressure intensity of the gas pressure adjusting device.

2. The intracranial pressure intelligent management system according to claim 1, characterized in that, The gas pressure adjusting device is arranged in the storage space, so that protection is realized through the outer cover.

3. The intracranial pressure intelligent management system of claim 1, wherein, A carrying handle is arranged on the top of the outer cover; the carrying handle is integrally formed with the outer cover or is detachably connected with the outer cover.

4. The intracranial pressure smart management system of claim 1, wherein, The pressure measuring section comprises a conical head and a cylindrical tube integrally formed with the conical head; the conical head is a thin-shell cavity body, a plurality of pressure contacts extend out of the cavity of the conical head through through-holes formed on the thin shell of the conical head, and a plurality of drainage holes are arranged through the thin shell of the conical head; a wire tube and a pipeline tube are arranged in the cylindrical tube, the wire tube is used to accommodate wires connected with the pressure contact and pressure electrode set, the pipeline tube is used to accommodate pipelines connected with the drainage holes and a drainage main pipe, and the wire tube is in communication with the pressure electrode set, and the pipeline tube is in communication with the drainage main pipe.

5. The intracranial pressure smart management system of claim 1, wherein, The start and stop of the micro liquid drainage pump are automatically controlled by the data processor: the data processor is pre-set with an intracranial pressure threshold range, when the processed intracranial pressure signal is higher than the upper limit of the threshold range, the data processor outputs a start signal to the micro liquid drainage pump; when the processed intracranial pressure signal falls below the lower limit of the threshold range, the data processor outputs a stop signal to the micro liquid drainage pump.

6. The intracranial pressure smart management system of claim 1, wherein, The shell of the connecting thin block is made of medical-grade polyether ether ketone or medical-grade polypropylene material, and the inner wall of the shell is provided with a reinforcing rib.

7. The intracranial pressure intelligent management system of claim 1, wherein, The pressure contact is made of medical-grade platinum-iridium alloy or medical-grade stainless steel material, and the outer surface of the pressure contact is provided with a polishing layer.

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