Transferring and storing device for breast cancer tissues and using method

The design of the lifting and sealing mechanism solves the problems of cold air leakage and tissue damage during the retrieval and placement of breast cancer tissue preservation devices, and realizes the preservation of cold air and safe transfer of tissue.

CN120942715AInactive Publication Date: 2025-11-14FIRST AFFILIATED HOSPITAL OF DALIAN MEDICAL UNIV +1
View PDF 1 Cites 0 Cited by

Patent Information

Application Number
CN202511315772.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-09-16
Publication Date
2025-11-14
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing breast cancer tissue preservation devices suffer from severe cold air leakage during retrieval and placement, and lack effective sealing and fixation mechanisms, leading to increased cold energy consumption and the risk of tissue damage.

Method used

The design incorporates a lifting and sealing mechanism. Through the cooperation of a wedge-shaped lifting plate and a fixing mechanism, breast cancer tissue can be easily placed, removed, and sealed, reducing cold air leakage. The negative pressure box and explosion-proof hose are used to fix the sealed bag and prevent tissue damage.

Benefits of technology

It effectively reduces the loss of cold air, ensures the retention of cold air, prevents mechanical damage to breast cancer tissue during transportation, and improves the convenience and safety of handling.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN120942715A_ABST
    Figure CN120942715A_ABST
Patent Text Reader

Abstract

The invention relates to the field of breast cancer, and discloses a breast cancer tissue transferring and storing device and a using method.The breast cancer tissue transferring and storing device comprises a protection frame, a partition plate is fixedly connected to the interior of the protection frame, jacking mechanisms are arranged at the bottom of the inner wall of the protection frame and the top of the partition plate correspondingly, and wedge-shaped lifting plates are arranged at the tops of the jacking mechanisms; a storage box is arranged on the outer side of the wedge-shaped lifting plate, and a sealing mechanism is arranged in the storage box. Through the arrangement of the jacking mechanism, the wedge-shaped lifting plate can be driven to ascend and descend when the protection box moves front and back, a worker can conveniently take and place breast cancer tissues into the protection box, and when the wedge-shaped lifting plate moves upwards, the fixing mechanism is driven to release adsorption and fixation of a sealing bag containing the breast cancer tissues; and when the wedge-shaped lifting plate moves downwards, the fixing mechanism can be driven to adsorb and fix the sealing bag, and mechanical damage to the breast cancer tissue in the subsequent transfer process is avoided.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] This invention relates to the field of breast cancer technology, specifically to a device and method for transporting and preserving breast cancer tissue. Background Technology

[0002] Breast cancer is a condition in which breast epithelial cells proliferate uncontrollably under the influence of various carcinogenic factors. Early symptoms often include breast lumps, nipple discharge, and enlarged axillary lymph nodes. In later stages, distant metastasis of cancer cells can lead to multi-organ complications, directly threatening the patient's life. For clinical diagnosis and treatment, pathological examination and the purification of DNA, RNA, and proteins require fresh breast cancer specimens. After collection, the breast cancer tissue is placed in a sealed bag, then cryopreserved and transported to the laboratory for pathological analysis.

[0003] For example, Chinese invention patent application number 202310239337.7, entitled "A Transport and Preservation Device and Method for Fresh Breast Cancer Tissue," discloses a transport and preservation device and method for fresh breast cancer tissue, relating to the field of breast cancer technology. The device includes: a breast cancer tissue transport mechanism; two sets of breast cancer tissue preservation mechanisms installed inside the transport mechanism; four sets of reset mechanisms installed on the front and rear sides of the transport mechanism; and four sets of breast cancer tissue storage mechanisms installed inside the two sets of storage mechanisms. When the operator pulls down the pull ring, the breast cancer tissue storage box moves, scraping against the inner walls of the storage box and the sealing baffle, facilitating cleaning. This solves the problem of inconvenience and increased cleaning difficulty for operators.

[0004] Shortcomings of existing technology: Since breast cancer tissue often only occupies part of the space in the breast cancer tissue preservation box, when the breast cancer tissue preservation box is pulled out to take out and put in breast cancer tissue, due to the lack of an adjustable sealing mechanism, it is impossible to seal the unused space of the breast cancer tissue preservation box with the protective frame. As a result, during the process of taking out and putting in breast cancer tissue, the cold air inside the protective frame will leak out in large quantities through the breast cancer tissue preservation box, causing a large loss of cold air and increasing the energy consumption of subsequent cooling. Because the breast cancer tissue preservation box lacks the function of securing the sealed bag containing the breast cancer tissue, the breast cancer tissue is prone to shaking inside the preservation box during transportation. This may cause mechanical damage to the breast cancer tissue due to impact (such as tissue tearing, cell membrane rupture, etc.), which in turn affects the accuracy of subsequent experimental results. Because the breast cancer tissue preservation box lacks a function to lift the sealed bag containing the breast cancer tissue, it is not convenient for staff to easily retrieve and place the breast cancer tissue into the box. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to provide a device and method for transporting and preserving breast cancer tissue, which effectively solves the problems in the background art.

[0006] To achieve the above objectives, the technical solution adopted by the present invention is as follows: a transport and preservation device for breast cancer tissue, comprising a protective frame, a partition fixedly connected inside the protective frame, a lifting mechanism provided at the bottom of the inner wall of the protective frame and the top of the partition, a wedge-shaped lifting plate provided at the top of the lifting mechanism, a preservation box provided on the outer side of the wedge-shaped lifting plate, a sealing mechanism provided inside the preservation box, the sealing mechanism dividing the inner cavity of the preservation box into a use cavity and a spare cavity, and multiple device slots provided on the wedge-shaped lifting plate, a fixing mechanism installed inside the device slots, a cooling mechanism provided inside the protective frame, a handle fixedly installed on the front of the preservation box, and a carrying handle fixedly installed on the top of the protective frame.

[0007] Preferably, the lifting mechanism includes a fixed block, a rack, and a slide rail. The fixed block is fixedly installed at the bottom of the storage box. A rotating shaft is rotatably connected to the fixed block. A bidirectional lead screw is fixedly sleeved on the outer surface of the rotating shaft, and a gear is fixedly sleeved on the outer surface of the rotating shaft. The gear meshes with the rack. In some cases, the rack in the lifting mechanism is fixedly installed on the top of the partition, and in others, it is fixedly installed on the bottom of the inner wall of the protective frame. Two threaded blocks are threadedly connected to the outer surface of the bidirectional lead screw. A T-shaped frame is fixedly connected to the top of each of the two threaded blocks. A connecting rod is hinged to the top of the T-shaped frame. The end of the connecting rod away from the T-shaped frame is hinged to the bottom of the wedge-shaped lifting plate. At least two connecting rods are hinged to the top of each T-shaped frame. A slider is slidably connected inside the slide rail. The slider is fixedly connected to the T-shaped frame. In some cases, the slide rail in the lifting mechanism is fixedly installed on the top of the partition, and in others, it is fixedly installed on the bottom of the inner wall of the protective frame.

[0008] Preferably, the sealing mechanism includes a guide rod and a threaded rod. The threaded rod is rotatably installed inside the storage box, and the guide rod is fixedly installed inside the storage box. Two sets of guide rods are provided and are located on both sides of the threaded rod. A sealing plate is threadedly connected to the outer surface of the threaded rod. The sealing plate is movably sleeved on the outside of the guide rod, and a second sealing plate is movably connected inside the first sealing plate. Multiple compression springs are fixedly connected between the second sealing plate and the first sealing plate. An adjustment knob is fixedly connected to one end of the threaded rod.

[0009] Preferably, the fixing mechanism includes a negative pressure box and a piston cylinder. The negative pressure box is fixedly installed inside the device slot, and the piston cylinder is fixedly installed at the bottom of the inner wall of the storage box via a support frame. A rubber pad is fixedly connected to the top of the negative pressure box. Both the rubber pad and the negative pressure box have several suction holes. An air extraction piston is movably connected inside the piston cylinder. A fixing rod is fixedly connected to the top of the air extraction piston. The top of the fixing rod movably passes through the piston cylinder and is fixedly connected to the bottom of the wedge-shaped lifting plate. The piston cylinder and the negative pressure box are connected by an explosion-proof hose. The explosion-proof hose is axially flexible but radially incompressible. This means that the explosion-proof hose has high compressive strength and rigidity in the radial direction perpendicular to the axis, making it difficult to be flattened, deformed, or damaged. This ensures that the explosion-proof hose can operate normally when extracting gas from inside the negative pressure box.

[0010] Preferably, the protective frame has heat dissipation vents, which are positioned corresponding to the location of the cooling mechanism.

[0011] Preferably, the cooling mechanism includes a fixed frame and a cooling fan. The fixed frame is fixedly installed on the inner wall of the protective frame and is opposite to the heat dissipation port. A semiconductor cooling chip is embedded in the fixed frame. The cooling end of the semiconductor cooling chip is located outside the fixed frame, and the heat dissipation end of the semiconductor cooling chip is located inside the fixed frame and is fixedly connected to heat dissipation fins.

[0012] Preferably, a dustproof mesh is fixedly connected inside the heat dissipation vent, and the cooling fan is fixedly installed on the dustproof mesh.

[0013] Preferably, the storage box has multiple cold air circulation holes.

[0014] Preferably, a battery, a PLC controller, and a temperature sensor are fixedly installed inside the protective frame, and a control switch is fixedly installed on the top of the protective frame.

[0015] The present invention also provides a method of using a transport and preservation device for breast cancer tissue, specifically including the following steps: S1: During use, the cooling mechanism is used to cool the inner cavity of the protective frame; S2: When breast cancer tissue needs to be stored in the storage box, the staff first adjusts the space of the use cavity according to the size of the breast cancer tissue to be stored. By turning the adjustment knob, the threaded rod is rotated, and under the limiting action of the guide rod and the sealing plate one, the sealing plate one moves along the axis of the threaded rod to adjust the space of the use cavity. At the same time, the elastic force of the compression spring keeps the sealing plate two in contact with the top of the wedge lifting plate. During the movement of the storage box, the lifting mechanism can drive the wedge lifting plate to move up. After the adjustment is completed, the storage box is moved to the outside of the protective frame until the front of the sealing plate one is flush with the front of the protective frame, so that only the use cavity inside the storage box is connected to the outside. This ensures that during the subsequent handling of breast cancer tissue, the cold air inside the protective frame cannot continue to leak cold air to the outside through the protective box, thereby reducing the loss of cold air. Then the staff places the sealed bag containing the breast cancer tissue in the use cavity and places it above the fixing mechanism. S3: After the breast cancer tissue is placed into the use cavity of the preservation box, the preservation box is pushed to move into the protective frame for repositioning. During this process, the wedge-shaped lifting plate is driven to descend and reposition through the lifting mechanism, which drives the breast cancer tissue placed on top of it to descend synchronously, so that the breast cancer tissue is completely inside the preservation box, thereby avoiding the preservation box being obstructed by the breast cancer tissue during the repositioning process and failing to be repositioned smoothly. S4: During the descent of the wedge-shaped lifting plate in step S3, the fixing rod will also move down synchronously, thereby driving the suction piston to move down, so as to extract the gas inside the negative pressure box through the explosion-proof hose. Since the top of the negative pressure box is covered by the sealing bag, the external gas cannot enter the negative pressure box from the suction hole, so that the negative pressure box is in a negative pressure environment. In this way, the suction hole can adsorb and fix the sealing bag, indirectly limiting and fixing the breast cancer tissue inside the sealing bag. Since the sealing bag is fixed and cannot move, the breast cancer tissue can only move slightly within the limited space inside the sealing bag during the subsequent transportation process. The sealing bag is made of flexible material, so even if the breast cancer tissue collides with the sealing bag, there will be no mechanical damage. S5: When it is necessary to remove the breast cancer tissue stored in the use cavity inside the storage box, the storage box is pulled outwards towards the protective frame until the sealing plate is flush with the protective frame. During this process, the lifting mechanism drives the wedge-shaped lifting plate to move upwards, lifting the breast cancer tissue to a certain height, making it easier for staff to remove the breast cancer tissue from the use cavity. When the wedge-shaped lifting plate moves upwards, it also simultaneously drives the fixing mechanism to release the suction fixation of the sealing bag, so that staff can easily remove the sealing bag.

[0016] The present invention has the following beneficial effects: The lifting mechanism allows the wedge-shaped lifting plate to move up and down as the protective box moves back and forth, facilitating the placement and removal of breast cancer tissue by staff. When the wedge-shaped lifting plate moves up, it releases the suction fixation of the sealed bag containing the breast cancer tissue, allowing staff to remove the bag. Conversely, when the wedge-shaped lifting plate moves down, it causes the fixing mechanism to suction fixation of the sealed bag, indirectly limiting and fixing the breast cancer tissue inside. Because the sealed bag is fixed and cannot move, the breast cancer tissue can only move slightly within the limited space inside the sealed bag during subsequent transport. Since the sealed bag is made of flexible material, even if the breast cancer tissue collides with the sealed bag, no mechanical damage will occur.

[0017] Rotating the adjustment knob drives the threaded rod to rotate, and under the limiting action of the guide rod and the pair of sealing plates, the sealing plates move along the axial direction of the threaded rod to adjust the space of the use cavity. When it is necessary to remove or place breast cancer tissue into the storage box, the storage box is pulled outward by the handle until the front of the sealing plate is flush with the front of the protective frame. At this time, only the use cavity inside the storage box is connected to the outside, thus ensuring that the cold air inside the protective frame cannot continue to leak to the outside through the protective box during the subsequent removal or placement of breast cancer tissue, thereby reducing the loss of cold air. Attached Figure Description

[0018] Figure 1 This is a three-dimensional schematic diagram of the overall structure of a transport and preservation device and method for breast cancer tissue proposed in this invention. Figure 2 This is a longitudinal sectional view of the overall structure of a transport and preservation device and method for breast cancer tissue proposed in this invention. Figure 3 This is a schematic diagram of the protective frame and partition, etc., of a transport and preservation device and method for breast cancer tissue proposed in this invention. Figure 4 This is a schematic diagram of the storage box and partition, etc., of a device for transporting and preserving breast cancer tissue and a method of use proposed in this invention. Figure 5 This is a schematic diagram of the structure of a storage box and guide ring, etc., of a transport and preservation device and method for breast cancer tissue proposed in this invention. Figure 6 This is a schematic diagram of a lifting mechanism for a transport and preservation device and method of using breast cancer tissue proposed in this invention; Figure 7 This is a longitudinal sectional view of a storage box for a transport and preservation device and method of using breast cancer tissue proposed in this invention. Figure 8This is a schematic diagram of the wedge-shaped lifting plate and sealing mechanism, etc., of a device for transporting and preserving breast cancer tissue and a method of use proposed in this invention. Figure 9 This is a schematic diagram of a wedge-shaped lifting plate and a lifting mechanism for a transport and preservation device and method of using breast cancer tissue proposed in this invention. Figure 10 An exploded view of the sealing mechanism of a breast cancer tissue transport and preservation device and its usage method proposed in this invention; Figure 11 This is an exploded view of the wedge-shaped lifting plate and fixing mechanism of a transport and preservation device and method for breast cancer tissue proposed in this invention; Figure 12 This is a longitudinal sectional view of the wedge-shaped lifting plate and fixing mechanism of a transport and preservation device and method for breast cancer tissue proposed in this invention. Figure 13 This is an exploded view of the refrigeration mechanism of a breast cancer tissue transport and preservation device and its usage method proposed in this invention.

[0019] In the diagram: 1. Protective frame; 2. Partition; 3. Lifting mechanism; 301. Fixed block; 302. Rack; 303. Rotating shaft; 304. Double-acting lead screw; 305. Gear; 306. Threaded block; 307. T-shaped frame; 308. Connecting rod; 309. Slide rail; 3010. Slider; 4. Wedge-shaped lifting plate; 5. Storage box; 6. Sealing mechanism; 601. Guide rod one; 602. Threaded rod; 603. Sealing plate one; 604. Sealing plate two; 605. Compression spring; 606. Adjusting knob; 7. Usage cavity; 8. Spare cavity; 9. Device slot; 10. Fixing mechanism; 1001. Negative pressure box; 1002. Piston cylinder; 1003. Rubber pad; 1004. Suction port; 1005. Suction piston; 1006. Fixing rod; 1007. Explosion-proof hose; 11. Refrigeration mechanism; 1101. Fixing frame; 1102. Cooling fan; 1103. Semiconductor refrigeration chip; 1104. Heat dissipation fins; 12. Handle; 13. Lifting handle; 14. Heat dissipation vent; 15. Dustproof mesh; 16. Cold air circulation hole; 17. Battery; 18. PLC controller; 19. Temperature sensor; 20. Control switch; 21. Guide rod two; 22. Guide ring. Detailed Implementation

[0020] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0021] As attached Figure 1 To be continued Figure 13 As shown: This invention provides a transport and preservation device for breast cancer tissue, including a protective frame 1, a partition 2 fixedly connected inside the protective frame 1, a lifting mechanism 3 provided at the bottom of the inner wall of the protective frame 1 and the top of the partition 2, a wedge-shaped lifting plate 4 provided at the top of the lifting mechanism 3, a preservation box 5 provided on the outside of the wedge-shaped lifting plate 4, a sealing mechanism 6 provided inside the preservation box 5, the sealing mechanism 6 dividing the inner cavity of the preservation box 5 into a use cavity 7 and a spare cavity 8, and a plurality of device slots 9 opened on the wedge-shaped lifting plate 4, a fixing mechanism 10 installed inside the device slots 9, a cooling mechanism 11 provided inside the protective frame 1, a handle 12 fixedly installed on the front of the preservation box 5, and a lifting handle 13 fixedly installed on the top of the protective frame 1; With the lifting mechanism 3 in place, the wedge-shaped lifting plate 4 can be driven to rise and fall when the protective box moves back and forth, so that staff can easily put breast cancer tissue into and take it out of the protective box. When the wedge-shaped lifting plate 4 moves up, it drives the fixing mechanism 10 to release the suction fixation of the sealed bag containing breast cancer tissue, so that staff can take the sealed bag containing breast cancer tissue away. When the wedge-shaped lifting plate 4 moves down, it drives the fixing mechanism 10 to suction fix the sealed bag, which indirectly limits and fixes the breast cancer tissue in the sealed bag. Since the sealed bag is fixed and cannot move, the breast cancer tissue can only move slightly within the limited space inside the sealed bag during subsequent transportation. The sealed bag is made of flexible material, so even if the breast cancer tissue collides with the sealed bag, there will be no mechanical damage. A guide ring is fixedly connected to the bottom of the storage box 5. A guide rod 2 is movably inserted inside the guide ring. The guide rod 2 is fixedly connected to the inner wall of the protective frame 1. The cooperation between the guide rod 2 and the guide ring can limit the movement of the storage box 5 and improve the stability of the storage box 5 during its forward and backward movement.

[0022] In a further embodiment of the present invention, the lifting mechanism 3 includes a fixing block 301, a rack 302, and a slide rail 309. The fixing block 301 is fixedly installed at the bottom of the storage box 5. A rotating shaft 303 is rotatably connected to the fixing block 301. A bidirectional lead screw 304 is fixedly sleeved on the outer surface of the rotating shaft 303, and a gear 305 is fixedly sleeved on the outer surface of the rotating shaft 303. The gear 305 meshes with the rack 302. In some lifting mechanisms 3, the rack 302 is fixedly installed on the top of the partition 2, and in others, the rack 302 is fixedly installed on the bottom of the inner wall of the protective frame 1. Two threaded blocks 3 are threadedly connected to the outer surface of the bidirectional lead screw 304. 06. T-shaped frames 307 are fixedly connected to the top of both threaded blocks 306. Connecting rods 308 are hinged to the top of the T-shaped frames 307. The end of the connecting rod 308 away from the T-shaped frame 307 is hinged to the bottom of the wedge-shaped lifting plate 4. At least two connecting rods 308 are hinged to the top of each T-shaped frame 307. A slider 3010 is slidably connected inside the slide rail 309. The slider 3010 is fixedly connected to the T-shaped frame 307. The slide rail 309 in some lifting mechanisms 3 is fixedly installed on the top of the partition plate 2. The slide rail 309 in some lifting mechanisms 3 is fixedly installed on the bottom of the inner wall of the protective frame 1. The T-shaped frame 307 and the threaded blocks 306 are integrally formed.

[0023] In a further embodiment of the present invention, the sealing mechanism 6 includes a guide rod 601 and a threaded rod 602. The threaded rod 602 is rotatably installed inside the storage box 5, and the guide rod 601 is fixedly installed inside the storage box 5. Two sets of guide rods 601 are provided and are located on both sides of the threaded rod 602. A sealing plate 603 is threadedly connected to the outer surface of the threaded rod 602. The sealing plate 603 is movably sleeved on the outside of the guide rod 601, and a second sealing plate 604 is movably connected inside the sealing plate 603. A plurality of compression springs 605 are fixedly connected between the second sealing plate 604 and the first sealing plate 603. An adjustment knob 606 is fixedly connected to one end of the threaded rod 602.

[0024] In a further embodiment of the present invention, the fixing mechanism 10 includes a negative pressure box 1001 and a piston cylinder 1002. The negative pressure box 1001 is fixedly installed inside the device groove 9, and the piston cylinder 1002 is fixedly installed at the bottom of the inner wall of the storage box 5 by a support frame. A rubber pad 1003 is fixedly connected to the top of the negative pressure box 1001. Both the rubber pad 1003 and the negative pressure box 1001 are provided with a plurality of suction holes 1004. An air suction piston 1005 is movably connected inside the piston cylinder 1002. A fixing rod 1006 is fixedly connected to the top of the air suction piston 1005. The top of 006 moves through the piston cylinder 1002 and is fixedly connected to the bottom of the wedge-shaped lifting plate 4. The piston cylinder 1002 and the negative pressure box 1001 are connected by an explosion-proof hose 1007. The explosion-proof hose 1007 is axially flexible but radially incompressible. This means that the explosion-proof hose 1007 has high compressive strength and rigidity in the radial direction perpendicular to the axis, and is difficult to be flattened, deformed or damaged. This ensures that the explosion-proof hose 1007 can operate normally when extracting gas from the inside of the negative pressure box 1001. The bottom end of the piston cylinder 1002 is provided with a through hole. Rotating the adjustment knob 606 drives the threaded rod 602 to rotate, and under the limiting action of the guide rod 601 on the sealing plate 603, the sealing plate 603 moves along the axial direction of the threaded rod 602 to adjust the space of the use cavity 7. When it is necessary to take breast cancer tissue into the storage box 5, the handle 12 is used to pull the storage box 5 outwards from the protective frame until the front of the sealing plate 603 is flush with the front of the protective frame 1. At this time, only the use cavity 7 inside the storage box 5 is connected to the outside, thus ensuring that the cold air inside the protective frame 1 cannot continue to leak cold air to the outside through the protective box during the subsequent removal and placement of breast cancer tissue, thereby reducing the loss of cold air.

[0025] In a further embodiment of the present invention, a heat dissipation vent 14 is provided on the protective frame 1, and is positioned corresponding to the cooling mechanism 11.

[0026] Furthermore, the cooling mechanism 11 includes a fixed frame 1101 and a cooling fan 1102. The fixed frame 1101 is fixedly installed on the inner wall of the protective frame 1 and is opposite to the heat dissipation port 14. A semiconductor cooling chip 1103 is embedded in the fixed frame 1101. The cooling end of the semiconductor cooling chip 1103 is located outside the fixed frame 1101, and the heat dissipation end of the semiconductor cooling chip 1103 is located inside the fixed frame 1101 and is fixedly connected to heat dissipation fins 1104. The arrangement of heat dissipation fins 1104 can increase the contact area between the heat dissipation end of the semiconductor cooling chip 1103 and the air, improve the heat dissipation effect and efficiency of the heat dissipation end of the semiconductor cooling chip 1103, and thus improve the cooling effect of the cooling end of the semiconductor cooling chip 1103.

[0027] Furthermore, a dustproof mesh 15 is fixedly connected inside the heat dissipation vent 14, and the cooling fan 1102 is fixedly installed on the dustproof mesh 15. The dustproof mesh 15 can intercept dust particles in the outside air, preventing dust particles from adhering to the heat dissipation fins 1104 or the cooling fan 1102. The cooling fan 1102 can accelerate the airflow efficiency between the inside of the fixed frame 1101 and the outside air, thereby improving the heat dissipation effect and efficiency of the heat dissipation end of the semiconductor cooling chip 1103.

[0028] In the embodiments provided by the present invention, the storage box 5 is provided with a plurality of cold air circulation holes 16. The cold air circulation holes 16 are provided so that the cold air inside the protective frame 1 can flow into the storage box 5, thereby preserving the breast cancer tissue stored in the storage box 5 at low temperature.

[0029] In the embodiments provided by the present invention, a battery 17, a PLC controller 18 and a temperature sensor 19 are fixedly installed inside the protective frame 1, and a control switch 20 is fixedly installed on the top of the protective frame 1. The temperature sensor 19, the thermoelectric cooler 1103 and the cooling fan 1102 are all electrically connected to the PLC controller 18, and the control switch 20 is electrically connected to control the thermoelectric cooler 1103 and the cooling fan 1102. The battery 17 is used to supply power to the electrical equipment.

[0030] The present invention also provides a method of using a transport and preservation device for breast cancer tissue, specifically including the following steps: S1: In use, the semiconductor cooling chip 1103 and the cooling fan 1102 are turned on by the control switch 20. The cooling end of the semiconductor cooling chip 1103 cools down the inside of the protective frame 1. At the same time, the temperature sensor 19 monitors the temperature of the inner cavity of the protective frame 1 and transmits the monitored data to the PLC controller 18. When the temperature of the inner cavity of the protective frame 1 reaches the preset value, the semiconductor cooling chip 1103 is turned off by the PLC controller 18 to stop cooling, so as to ensure that the temperature of the inner cavity of the protective frame 1 is in a suitable constant temperature state and improve the effect of low temperature preservation of breast cancer tissue. S2: When breast cancer tissue needs to be stored in the storage box 5, the staff first adjusts the space of the use cavity 7 according to the size of the breast cancer tissue to be stored. By rotating the adjustment knob 606, the threaded rod 602 is rotated. Under the limiting action of the guide rod 601 on the sealing plate 603, the sealing plate 603 moves along the axial direction of the threaded rod 602 to adjust the space of the use cavity 7. At the same time, the elastic force of the compression spring 605 keeps the sealing plate 604 in contact with the top of the wedge-shaped lifting plate 4. During the movement of the storage box 5, the gear 305 moves synchronously, and the gear 305 meshes with the rack 302, so that the gear 305 rotates while moving, and drives the rotating shaft 303 and the bidirectional lead screw 304 to rotate. The slide rail 309 and the slider 3010 limit the T-shaped frame 307 and the threaded block 306, causing the T-shaped frame 307 and the threaded block 306 to move along the axial direction of the two-way screw 304, and push the wedge-shaped lifting plate 4 upward through multiple connecting rods 308. After adjustment, the storage box 5 is pulled to the outside of the protective frame by the handle 12 until the front of the sealing plate 603 is flush with the front of the protective frame 1. At this time, only the use cavity 7 inside the storage box 5 is connected to the outside, thus ensuring that the cold air inside the protective frame 1 cannot continue to leak cold air to the outside through the protective box during the subsequent removal and placement of breast cancer tissue, so as to reduce the loss of cold air. Then, the staff places the sealed bag containing breast cancer tissue in the use cavity 7 and places it above the fixing mechanism 10. S3: After the breast cancer tissue is placed into the use cavity 7 inside the preservation box 5, push the preservation box 5 to move into the protective frame for repositioning. During this process, the lifting mechanism 3 drives the wedge lifting plate 4 to descend and reposition, which drives the breast cancer tissue placed on top of it to descend synchronously, so that the breast cancer tissue is completely inside the preservation box 5, thereby avoiding the preservation box 5 from being obstructed by the breast cancer tissue during the repositioning process and failing to be repositioned smoothly. S4: During the descent of the wedge-shaped lifting plate 4 in step S3, the fixing rod 1006 will also move down synchronously, thereby driving the suction piston 1005 to move down, so as to extract the gas inside the negative pressure box 1001 through the explosion-proof hose 1007. Since the top of the negative pressure box 1001 is covered by the sealing bag, the external gas cannot enter the negative pressure box 1001 through the suction hole 1004, so that the negative pressure box 1001 is in a negative pressure environment. Then, the suction hole 1004 will have the effect of adsorbing and fixing the sealing bag, indirectly limiting and fixing the breast cancer tissue inside the sealing bag. Since the sealing bag is fixed and cannot move, during the subsequent transportation process, the breast cancer tissue can only move slightly within the limited space inside the sealing bag. The sealing bag is made of flexible material, so even if the breast cancer tissue collides with the sealing bag, there will be no mechanical damage. S5: When it is necessary to remove the breast cancer tissue stored in the use cavity 7 inside the storage box 5, the storage box 5 is pulled outwards towards the protective frame 1 until the sealing plate 603 is flush with the protective frame 1. During this process, the lifting mechanism 3 drives the wedge-shaped lifting plate 4 to move upwards, lifting the breast cancer tissue to a certain height, so that the staff can easily remove the breast cancer tissue from the use cavity 7. When the wedge-shaped lifting plate 4 moves upwards, it also simultaneously drives the fixing mechanism 10 to release the suction fixation of the sealing bag, so that the staff can easily remove the sealing bag.

[0031] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A device for transporting and preserving breast cancer tissue, comprising a protective frame (1), characterized in that: The protective frame (1) is fixedly connected to a partition (2). The bottom of the inner wall of the protective frame (1) and the top of the partition (2) are both provided with a lifting mechanism (3). The top of the lifting mechanism (3) is provided with a wedge-shaped lifting plate (4). A storage box (5) is provided on the outside of the wedge-shaped lifting plate (4). A sealing mechanism (6) is provided inside the storage box (5). The sealing mechanism (6) divides the inner cavity of the storage box (5) into a use cavity (7) and a spare cavity (8). A plurality of device slots (9) are opened on the wedge-shaped lifting plate (4). A fixing mechanism (10) is installed inside the device slots (9). A cooling mechanism (11) is provided inside the protective frame (1).

2. The device for transporting and preserving breast cancer tissue according to claim 1, characterized in that: The lifting mechanism (3) includes a fixed block (301), a rack (302), and a slide rail (309). The fixed block (301) is fixedly installed at the bottom of the storage box (5). A rotating shaft (303) is rotatably connected to the fixed block (301). A bidirectional lead screw (304) is fixedly sleeved on the outer surface of the rotating shaft (303), and a gear (305) is fixedly sleeved at the position of the outer surface of the rotating shaft (303). The outer surface of the bidirectional lead screw (304) is threaded. There are two threaded blocks (306), and a T-shaped frame (307) is fixedly connected to the top of each of the two threaded blocks (306). A connecting rod (308) is hinged to the top of the T-shaped frame (307). The end of the connecting rod (308) away from the T-shaped frame (307) is hinged to the bottom of the wedge-shaped lifting plate (4). A slider (3010) is slidably connected inside the slide rail (309), and the slider (3010) is fixedly connected to the T-shaped frame (307).

3. The device for transporting and preserving breast cancer tissue according to claim 1, characterized in that: The sealing mechanism (6) includes a guide rod (601) and a threaded rod (602). The threaded rod (602) is rotatably installed inside the storage box (5). The guide rod (601) is fixedly installed inside the storage box (5). The guide rod (601) is provided in two sets and is located on both sides of the threaded rod (602). The outer surface of the threaded rod (602) is threadedly connected to a sealing plate (603). The sealing plate (603) is movably sleeved on the outside of the guide rod (601). The sealing plate (603) is movably connected to a sealing plate (604) inside the sealing plate (603). Multiple compression springs (605) are fixedly connected between the sealing plate (604) and the sealing plate (603). An adjustment knob (606) is fixedly connected to one end of the threaded rod (602).

4. The device for transporting and preserving breast cancer tissue according to claim 1, characterized in that: The fixing mechanism (10) includes a negative pressure box (1001) and a piston cylinder (1002). The negative pressure box (1001) is fixedly installed inside the device slot (9). The piston cylinder (1002) is fixedly installed at the bottom of the inner wall of the storage box (5) by a support frame. A rubber pad (1003) is fixedly connected to the top of the negative pressure box (1001). Several suction holes (1004) are opened on both the rubber pad (1003) and the negative pressure box (1001). A suction piston (1005) is movably connected inside the piston cylinder (1002). A fixing rod (1006) is fixedly connected to the top of the suction piston (1005). The top of the fixing rod (1006) movably passes through the piston cylinder (1002) and is fixedly connected to the bottom of the wedge-shaped lifting plate (4). The piston cylinder (1002) and the negative pressure box (1001) are connected by an explosion-proof hose (1007).

5. A device for transporting and preserving breast cancer tissue according to claim 1, characterized in that: The protective frame (1) has a heat dissipation vent (14) which is positioned corresponding to the cooling mechanism (11).

6. A transport and preservation device for breast cancer tissue according to claim 5, characterized in that: The cooling mechanism (11) includes a fixed frame (1101) and a cooling fan (1102). The fixed frame (1101) is fixedly installed on the inner wall of the protective frame (1) and is opposite to the heat dissipation port (14). A semiconductor cooling chip (1103) is embedded in the fixed frame (1101). The cooling end of the semiconductor cooling chip (1103) is located outside the fixed frame (1101), and the heat dissipation end of the semiconductor cooling chip (1103) is located inside the fixed frame (1101) and is fixedly connected to a heat dissipation fin (1104).

7. A transport and preservation device for breast cancer tissue according to claim 6, characterized in that: A dustproof net (15) is fixedly connected inside the heat dissipation port (14), and the cooling fan (1102) is fixedly installed on the dustproof net (15).

8. A transport and preservation device for breast cancer tissue according to claim 1, characterized in that: The storage box (5) has multiple cold air circulation holes (16).

9. A transport and preservation device for breast cancer tissue according to claim 1, characterized in that: The protective frame (1) is fixedly installed with a battery (17), a PLC controller (18) and a temperature sensor (19), and a control switch (20) is fixedly installed on the top of the protective frame (1).

10. A method of using a transport and preservation device for breast cancer tissue, the transport and preservation device for breast cancer tissue according to any one of claims 1-9, characterized in that: Specifically, the following steps are included: S1: When in use, the cooling mechanism (11) is used to cool the inner cavity of the protective frame (1); S2: When breast cancer tissue needs to be stored in the storage box (5), the staff first adjusts the space of the use cavity (7) according to the size of the breast cancer tissue to be stored. By rotating the adjustment knob (606), the threaded rod (602) is rotated. Under the limiting action of the guide rod (601) on the sealing plate (603), the sealing plate (603) moves along the axial direction of the threaded rod (602) to adjust the space of the use cavity (7). At the same time, the elastic force of the compression spring (605) keeps the sealing plate (604) in contact with the top of the wedge-shaped lifting plate (4) and keeps it in place. During the movement of the storage box (5), the lifting mechanism (3) can drive the wedge lifting plate (4) to move upward. After adjustment, the storage box (5) is moved to the outside of the protective frame until the front of the sealing plate (603) is flush with the front of the protective frame (1), so that only the use cavity (7) inside the storage box (5) is connected to the outside. This ensures that the cold air inside the protective frame (1) cannot continue to leak cold air to the outside through the protective box during the subsequent removal and placement of breast cancer tissue, thereby reducing the loss of cold air. Then, the staff places the sealed bag containing breast cancer tissue in the use cavity (7) and above the fixing mechanism (10). S3: When the breast cancer tissue is placed into the use cavity (7) inside the storage box (5), push the storage box (5) to move into the protective frame for repositioning. During this process, the wedge lifting plate (4) is driven to descend and reposition through the lifting mechanism (3), which drives the breast cancer tissue placed on top of it to descend synchronously, so that the breast cancer tissue is completely inside the storage box (5), thereby avoiding the obstruction of the breast cancer tissue during the repositioning process of the storage box (5) and thus preventing it from being repositioned smoothly. S4: During the descent of the wedge-shaped lifting plate (4) in step S3, the fixing rod (1006) will also be driven to move down synchronously, thereby driving the suction piston (1005) to move down, so as to extract the gas inside the negative pressure box (1001) through the explosion-proof hose (1007). Since the top of the negative pressure box (1001) is covered by the sealing bag, the external gas cannot enter the negative pressure box (1001) through the suction hole (1004), so that the negative pressure box (1001) is in a negative pressure environment, and thus the suction hole (1004) can adsorb and fix the sealing bag, indirectly limiting and fixing the breast cancer tissue in the sealing bag. S5: When it is necessary to remove the breast cancer tissue stored in the use cavity (7) inside the storage box (5), the storage box (5) is pulled outwards towards the protective frame (1) until the sealing plate (603) is flush with the protective frame (1). During this process, the lifting mechanism (3) drives the wedge lifting plate (4) to move upwards, lifting the breast cancer tissue to a certain height, so that the staff can remove the breast cancer tissue from the use cavity (7). When the wedge lifting plate (4) moves upwards, it also drives the fixing mechanism (10) to release the suction fixation of the sealing bag, so that the staff can take the sealing bag away smoothly.

Citation Information

Patent Citations

  • A device and method for transporting and preserving fresh breast cancer tissue

    CN116210680B