Correlation method and device for children pneumonia auscultation sound and traditional Chinese medicine diagnosis data and storage medium
By collecting and analyzing auscultation sounds from the heart and lungs of children, and combining Western medical signs and traditional Chinese medicine syndrome types, a method for linking auscultation sounds with traditional Chinese medicine syndrome differentiation was established. This solved the problem of traditional auscultation methods relying on experience, and enabled rapid diagnosis and effective treatment.
Patent Information
- Application Number
- CN202511502069.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-21
- Publication Date
- 2025-11-18
- Estimated Expiration
- 2045-10-21
AI Technical Summary
Traditional auscultation methods rely heavily on doctors' experience when diagnosing pneumonia in children, resulting in untimely diagnosis and a lack of objective quantitative reference. Traditional Chinese medicine syndrome differentiation relies on subjective factors and lacks objective evidence.
Collect auscultation sounds from the heart and lungs of children, analyze signal characteristics to determine Western medicine signs, combine with TCM syndrome types to provide TCM medication recommendations, establish a correlation method between auscultation sounds and TCM syndrome differentiation, and use electronic stethoscopes and data processing technology to achieve rapid diagnosis and treatment suggestions.
It provides objective evidence for TCM syndrome differentiation, improves the speed of diagnosis and timeliness of treatment for childhood pneumonia, and enhances the objectivity and accuracy of TCM treatment efficacy evaluation.
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Figure CN120959783A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of data processing, in particular to a method, device and storage medium for associating auscultation sound of pediatric pneumonia with TCM diagnosis data. BACKGROUND
[0002] Auscultation sound (especially fine moist rales and wheezing sound) of pediatric pneumonia is one of the key signs for Western medicine to diagnose pneumonia. In the perspective of traditional Chinese medicine (TCM), these auscultation sounds are an important part of "listening diagnosis" and directly reflect the core pathogenesis such as "phlegm, heat, obstruction and wheezing". Auscultation sound provides strong objective evidence and quantitative reference for TCM syndrome differentiation (especially for excess syndromes such as phlegm-heat obstructing lung and toxic-heat obstructing lung). TCM highly depends on and integrates the results of auscultation when diagnosing and treating pediatric pneumonia, which is one of the key bases for syndrome differentiation, prescription selection (especially for the selection of phlegm-reducing and wheezing-relieving drugs), and evaluation of efficacy and prognosis.
[0003] The key of integration of traditional Chinese and Western medicine is to enrich and verify the "listening diagnosis" and syndrome differentiation of TCM by the objectivity and accuracy of Western medicine auscultation, and to improve symptoms (such as cough, wheezing and sputum) and promote lung inflammation absorption and recovery by individualized treatment according to pathogenesis (including pathogenesis reflected by auscultation) combining with the advantages of TCM holistic view and syndrome differentiation and treatment.
[0004] Therefore, in clinical practice, pediatricians with Western or TCM background will pay great attention to the results of auscultation when diagnosing and treating pediatric pneumonia. TCM practitioners will organically integrate these results into the framework of TCM four examinations, making the syndrome differentiation more accurate and the treatment more targeted. The dynamic changes of auscultation sound are also one of the important objective indicators for evaluating the effect of TCM in treating pneumonia. SUMMARY
[0005] The main purpose of the present application is to provide a method, device and storage medium for associating auscultation sound of pediatric pneumonia with TCM diagnosis data, which aims to provide strong objective evidence and quantitative reference for TCM syndrome differentiation, especially for excess syndromes such as phlegm-heat obstructing lung and toxic-heat obstructing lung. TCM highly depends on and integrates the results of auscultation when diagnosing and treating pediatric pneumonia, which is one of the key bases for syndrome differentiation, prescription selection (especially for the selection of phlegm-reducing and wheezing-relieving drugs), and evaluation of efficacy and prognosis.
[0006] To achieve the above purpose, the present application provides a method for associating auscultation sound of pediatric pneumonia with TCM diagnosis data, which comprises: collecting heart and lung auscultation sound signals of a child to be diagnosed, determining the representation of auscultation sound in Western medicine auxiliary examination corresponding to the auscultation sound signals, and the Western medicine signs including the representation of auscultation sound; determining the TCM syndrome type in TCM syndrome differentiation corresponding to the representation of auscultation sound; According to the Western medicine signs and / or the TCM syndrome type, a TCM medication recommendation for the to-be-diagnosed child is determined.
[0007] In an embodiment, the step of determining the representation of the auscultation sound in the Western medicine auxiliary examination corresponding to the auscultation sound signal comprises: extracting signal features of the auscultation sound signal, the signal features comprising at least one of time domain features, frequency domain features, time-frequency features, and perceptual features; the time domain features comprising at least one of amplitude envelope, zero-crossing rate, energy, root mean square energy, peak amplitude, autocorrelation function; the frequency domain features comprising at least one of spectral centroid, spectral bandwidth, spectral spread, spectral flatness, spectral roll-off point, spectral flux, mel-frequency cepstral coefficient, chroma features, loudness profile features; the time-frequency features comprising at least one of spectrogram, constant-Q transform, wavelet transform coefficients; the perceptual features comprising at least one of loudness, pitch, timbre; determining the Western medicine signs according to the signal features, the Western medicine signs comprising at least one of the representation of the auscultation sound, at least one of fine moist rales, coarse moist rales, wheezing sound, weakened or disappeared breath sound, and tubular breath sound.
[0008] In an embodiment, the step of determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound comprises: determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared breath sound, and the tubular breath sound.
[0009] In an embodiment, the step of determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared breath sound, and the tubular breath sound comprises: when there are dense fine moist rales accompanied by coarse moist rales, and accompanied by breath sound changes, determining that the TCM syndrome type is phlegm-heat obstructing lung syndrome; when there are dense fine moist rales in a preset lung range, and there are tubular breath sound and weakened breath sound, determining that the TCM syndrome type is toxic-heat obstructing lung syndrome; when there are coarse breath sounds in the early stage and wet rales in the later stage, determining that the TCM syndrome type is wind-cold obstructing lung syndrome; when there are coarse breath sounds, and dense moist rales and wheezing sound, determining that the TCM syndrome type is wind-heat obstructing lung syndrome; when the moist rales are reduced or disappeared, and the breath sound is normal, determining that the TCM syndrome type is yin deficiency and lung heat syndrome; When there is no rale or occasional moist rale, and the breath sound is normal, the TCM syndrome type is determined as lung and spleen qi deficiency syndrome.
[0010] In an embodiment, the step of determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound according to at least one of the fine moist rale, the coarse moist rale, the wheezing sound, the weakened or disappeared breath sound, and the tubular breath sound comprises: obtaining other TCM data, the other TCM data including inspection data, auscultation data, and palpation data, the auscultation data including sounds heard by a doctor and smells smelled by the doctor; determining a syndrome type in the TCM syndrome differentiation type corresponding to the western medical sign according to at least one of the fine moist rale, the coarse moist rale, the wheezing sound, the weakened or disappeared breath sound, and the tubular breath sound, and the other TCM data.
[0011] In an embodiment, the step of determining the TCM medicine recommendation for the child to be diagnosed according to the western medical sign and / or the TCM syndrome type comprises: when the western medical sign and / or the TCM syndrome type corresponds to a moist rale, determining that the TCM medicine recommendation includes a traditional Chinese medicine for reducing phlegm; when the western medical sign and / or the TCM syndrome type corresponds to a wheezing sound, determining that the TCM medicine recommendation includes a traditional Chinese medicine for relieving asthma, opening the lung, and reducing phlegm; when the western medical sign and / or the TCM syndrome type corresponds to a weakened breath sound or a tubular breath sound, determining that the TCM medicine recommendation includes a traditional Chinese medicine for opening the lung and clearing heat and resolving toxins; when the western medical sign and / or the TCM syndrome type corresponds to a disappeared auscultation sound in the recovery period, determining that the TCM medicine recommendation includes a traditional Chinese medicine for nourishing yin and clearing the lung or for invigorating the spleen and supplementing the lung.
[0012] In an embodiment, after the step of determining the TCM medicine recommendation for the child to be diagnosed according to the western medical sign and / or the TCM syndrome type, the method further comprises: reacquiring a new auscultation sound signal of the child to be diagnosed in a treatment process; determining a new western medical sign corresponding to the new auscultation sound signal; determining a sign change condition between the western medical sign before treatment and the new western medical sign, the sign change condition including a changed sign and a changed degree; determining a disease severity condition and a recovery condition of the child to be diagnosed according to the sign change condition, the disease severity condition and the recovery condition being used to prompt whether the TCM medicine recommendation needs to be adjusted.
[0013] In an embodiment, before the step of determining the type of TCM syndrome in the TCM syndrome type corresponding to the representation of the auscultation sound, the method further comprises: acquiring type information of the child pneumonia patient, the type information comprising at least one of age and disease course stage; grouping the child pneumonia patient into at least one preset group according to the type information, collecting an audio reference signal of the heart and lung of the child pneumonia patient in the preset group, and determining a reference representation of the auscultation sound corresponding to the audio reference signal; determining a reference type of TCM syndrome in the TCM syndrome type corresponding to the reference representation of the auscultation sound, and establishing an association between the reference representation of the auscultation sound and the reference type of TCM syndrome in the TCM syndrome type; The step of determining the type of TCM syndrome in the TCM syndrome type corresponding to the representation of the auscultation sound comprises: According to the association, determining the type of TCM syndrome in the TCM syndrome type corresponding to the representation of the auscultation sound of the child to be diagnosed.
[0014] In addition, to achieve the above-mentioned purpose, the present application also provides an auscultation device, which comprises a memory, a processor and a computer program stored on the memory and executable on the processor, and the computer program is configured to implement the steps of the association method of the auscultation sound of child pneumonia and TCM diagnosis data as described above.
[0015] In addition, to achieve the above-mentioned purpose, the present application also provides a storage medium, which is a computer readable storage medium, and the storage medium stores a computer program, and the computer program is executed by a processor to implement the steps of the association method of the auscultation sound of child pneumonia and TCM diagnosis data as described above.
[0016] In addition, to achieve the above-mentioned purpose, the present application also provides a computer program product, which comprises a computer program, and the computer program is executed by a processor to implement the steps of the association method of the auscultation sound of child pneumonia and TCM diagnosis data as described above.
[0017] The one or more technical solutions provided by the present application have at least the following technical effects: The heart and lung auscultation sound signals of the children to be diagnosed are collected, the western medicine signs corresponding to the auscultation sound signals are determined, the western medicine signs include the representation of the auscultation sound; the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound is determined; and the TCM medication recommendation of the children to be diagnosed is determined according to the western medicine signs and / or the TCM syndrome type. Through the relationship between the western medicine signs and the TCM syndrome type, strong objective evidence and quantitative reference are provided for the TCM syndrome differentiation, especially the excess syndrome such as phlegm-heat obstructing lung and toxic-heat obstructing lung. In the diagnosis and treatment of children's pneumonia, TCM highly depends on and integrates the auscultation results, which is used as the key basis for syndrome differentiation, prescription selection (especially the selection of phlegm-heat and asthma relieving drugs), and evaluation of curative effect and prognosis. BRIEF DESCRIPTION OF DRAWINGS
[0018] The drawings incorporated into the specification and forming part of the specification, show embodiments consistent with the present application, and together with the specification, serve to explain the principles of the present application.
[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the drawings needed to be used in the embodiments or prior art description will be briefly introduced as follows, and obviously, other drawings can also be obtained by those skilled in the art without creative labor.
[0020] Figure 1 The flowchart provided for the first embodiment of the method for associating the auscultation sound of children's pneumonia with TCM diagnosis data of the present application; Figure 2 The flowchart provided for the second embodiment of the method for associating the auscultation sound of children's pneumonia with TCM diagnosis data of the present application; Figure 3 The data fusion flowchart provided for the second embodiment of the method for associating the auscultation sound of children's pneumonia with TCM diagnosis data of the present application; Figure 4 The flowchart provided for the third embodiment of the method for associating the auscultation sound of children's pneumonia with TCM diagnosis data of the present application; Figure 5 The flowchart provided for the fourth embodiment of the method for associating the auscultation sound of children's pneumonia with TCM diagnosis data of the present application; Figure 6 The flowchart provided for the fifth embodiment of the method for associating the auscultation sound of children's pneumonia with TCM diagnosis data of the present application; Figure 7 The device structure schematic diagram of the hardware running environment involved in the method for associating the auscultation sound of children's pneumonia with TCM diagnosis data in the embodiments of the present application.
[0021] The purpose implementation, functional characteristics and advantages of the present application will be further explained with reference to the embodiments and the drawings. DETAILED DESCRIPTION
[0022] It should be understood that the specific embodiments described herein are merely for the purpose of illustrating the technical solutions of the present application and are not intended to limit the present application.
[0023] In order to better understand the technical solutions of the present application, the following will be described in detail in combination with the drawings of the specification and specific embodiments.
[0024] The traditional auscultation method has certain limitations in the diagnosis process, and the diagnosis result is highly dependent on the clinical experience of the doctor, and multiple diagnostic items need to be checked for auxiliary diagnosis, which ultimately leads to the delay of the diagnosis of pediatric pneumonia.
[0025] The main solution of the embodiment of the present application is to collect the heart and lung auscultation sound signals of the child to be diagnosed, determine the representation of the auscultation sound in the western medicine auxiliary examination corresponding to the auscultation sound signal, and the western medicine signs include the representation of the auscultation sound; determine the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound; and determine the TCM medication recommendation for the child to be diagnosed according to the western medicine signs and / or TCM syndrome type.
[0026] In the present embodiment, for the convenience of description, the following is described with the auscultation device as the execution subject.
[0027] The present application provides a solution, which provides strong objective evidence and quantitative reference for TCM syndrome differentiation, especially for phlegm-heat obstructing lung, toxic heat obstructing lung and other excess syndromes, through the relationship between western medicine signs and syndrome types of TCM syndrome differentiation, quickly diagnoses and determines the syndrome type corresponding to the auscultation sound signal and the TCM medication recommendation, and improves the diagnosis speed of pediatric pneumonia and the key basis for evaluating the efficacy and prognosis of pediatric pneumonia treatment in TCM.
[0028] It should be noted that the execution subject of the present embodiment can be a computing service device with data processing, network communication and program running functions, such as a tablet computer, a personal computer, a mobile phone, etc., or an electronic device, an auscultation device, etc. which can realize the above functions, wherein the auscultation device can also be called a pediatric pneumonia auscultation sound and TCM diagnosis data association device. The following will take the auscultation device as an example to describe the present embodiment and each of the following embodiments.
[0029] Based on this, the present embodiment provides a pediatric pneumonia auscultation sound and TCM diagnosis data association method, which refers to Figure 1 , Figure 1 The flowchart of the first embodiment of the pediatric pneumonia auscultation sound and TCM diagnosis data association method of the present application.
[0030] In the present embodiment, the pediatric pneumonia auscultation sound and TCM diagnosis data association method comprises steps S10-S30: In step S10, the heart and lung auscultation sound signal of the child to be diagnosed is collected, and the representation of the auscultation sound in the western medical auxiliary examination corresponding to the auscultation sound signal is determined. The western medical sign includes the representation of the auscultation sound.
[0031] The auscultation sound signal is a sound signal generated by airflow through the airway and alveoli during the breathing process recorded by an auscultation device, reflecting the airway patency, lung tissue elasticity and abnormal lesions. Optionally, the auscultation device can be a traditional stethoscope, an electronic stethoscope, a wearable device, etc.
[0032] In actual application, the electronic stethoscope is close to the heart and lung of the child to be diagnosed, the electronic stethoscope collects the auscultation sound signal of the heart and lung of the child to be diagnosed, and the electronic stethoscope directly analyzes the auscultation sound signal, thereby quickly diagnosing the child pneumonia and quickly obtaining the corresponding TCM syndrome differentiation type, which is beneficial to TCM prescription selection, corresponding treatment, dynamic understanding of curative effect and prognosis.
[0033] In the application scenario of telemedicine, the parent collects the auscultation sound signal of the heart and lung of the child to be diagnosed by the electronic stethoscope, and uploads the auscultation sound signal of the heart and lung of the child to be diagnosed to the network end. The network end applies the method of the present application to the initial diagnosis based on the auscultation sound signal, diagnoses the child pneumonia, avoids wasting the diagnosis time of the parent on the way, and ensures the timeliness of the diagnosis of the child pneumonia. Optionally, after diagnosing the child pneumonia, online TCM consultation is connected.
[0034] In the present application, the western medical sign mainly includes the representation of the auscultation sound, that is, the auscultation sound result, wherein the auscultation sound includes moist rales, breath sounds, wheezing sounds and tubular breath sounds, etc. Optionally, the auscultation sound includes moist rales, breath sounds, wheezing sounds and tubular breath sounds at different stages of disease course, and can also include moist rales, breath sounds, wheezing sounds and tubular breath sounds at different degrees. Exemplarily, the auscultation sound includes fine moist rales, coarse moist rales, large water bubble sound, wheezing sound, weakened or disappeared breath sound, tubular breath sound, bronchial breath sound, etc.
[0035] In the western medical sign, fine moist rales have the most diagnostic significance. Fine moist rales are obvious at the end of inspiration, with fine, dense and superficial sound, like the sound of twisting hair or the sound of water bubble breaking. Fine moist rales indicate that there is inflammatory exudate in the alveoli or small bronchi, which is a typical sign of alveolitis. In the field of traditional Chinese medicine, it indicates the existence of phlegm, phlegm turbidity or phlegm heat obstructing the lung.
[0036] In the western medical sign, coarse moist rales or large water bubble sound is obvious in the early inspiration, with relatively coarse and loud sound. Coarse moist rales or large water bubble sound indicates that there is a large amount of thin secretions in the trachea, main bronchus or cavity. In the field of traditional Chinese medicine, it is considered as a sign of phlegm turbidity.
[0037] In Western medicine, wheezing is a high-pitched whistling sound during exhalation. Wheezing suggests small airway constriction or narrowing, often seen in asthmatic pneumonia, syncytial virus infection, some mycoplasma pneumonia, and allergic factors. In the field of traditional Chinese medicine, this is closely related to lung qi stagnation and phlegm qi obstruction, and is an important sign of asthma.
[0038] In Western medicine, decreased or absent breath sounds suggest a large area of lung consolidation, pleural effusion, pneumothorax, or complete obstruction of the bronchus. In the field of traditional Chinese medicine, it is generally considered to be a serious condition of lung qi stagnation or lung qi obstruction.
[0039] In Western medicine, tubular or bronchial breath sounds are similar to those heard in the main bronchus, with a strong expiratory phase and high-pitched tone. Tubular or bronchial breath sounds suggest lung consolidation, such as lung tissue densification and enhanced transmission, and also suggest lung qi obstruction.
[0040] Step S20, determining the type of TCM syndrome in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound.
[0041] In this embodiment, the representation of the auscultation sound is associated with the type of syndrome in the TCM syndrome differentiation type. After determining the representation of the auscultation sound, the type of syndrome in the TCM syndrome differentiation type corresponding to the type of auscultation sound is determined based on the association.
[0042] In the field of traditional Chinese medicine, TCM syndrome differentiation is used to determine the type of syndrome, and the type of syndrome is the specific conclusion drawn after TCM syndrome differentiation. The two are interrelated and provide a basis for diagnosis and treatment in traditional Chinese medicine. The occurrence and development of diseases are the result of physiological dysfunction of organs, meridians, and blood under the action of pathogenic factors. TCM syndrome differentiation is a comprehensive analysis of various symptoms, signs, medical history, and other information of patients under the guidance of TCM theory, to identify the organs, meridians, and judge the cause, nature, and severity of the disease, so as to classify the disease into a certain specific type of syndrome. The type of syndrome is the result of TCM syndrome differentiation. The type of syndrome is a summary of the nature of the current stage of the disease, and a comprehensive summary of the cause, location, nature, and severity of the disease at a certain stage.
[0043] In clinical practice, pediatricians (whether Western or Chinese medicine) pay great attention to the results of auscultation when diagnosing and treating pediatric pneumonia. Traditional Chinese medicine practitioners will organically integrate these results into the framework of TCM four diagnostic methods, making the diagnosis more accurate and the treatment more targeted. The dynamic changes of auscultation sound are also one of the important objective indicators for evaluating the effect of traditional Chinese medicine in treating pneumonia.
[0044] Step S30, determining the recommended traditional Chinese medicine for the child to be diagnosed based on the Western medical signs and / or the type of TCM syndrome.
[0045] The objectivity and accuracy of Western medicine auscultation are used to enrich and verify the TCM auscultation and syndrome differentiation, and the advantages of TCM holistic view and syndrome differentiation and treatment are used for individualized treatment according to pathogenesis, to improve the symptoms of pneumonia and promote the absorption and recovery of lung inflammation.
[0046] Optionally, the TCM medication recommendation for the child to be diagnosed is determined according to the Western medicine signs. Different Western medicine signs correspond to different TCM medication recommendations.
[0047] Optionally, the TCM medication recommendation for the child to be diagnosed is determined according to the syndrome type. Different syndrome types correspond to different TCM medication recommendations. For example, for a child with TCM syndrome differentiation of phlegm-heat obstructing lung, the TCM formula may contain heat-clearing and phlegm-resolving drugs such as Gualou and Beimu, and targeted medication can better regulate the body function of the child and achieve the purpose of treating the disease.
[0048] Optionally, the TCM medication recommendation for the child to be diagnosed is determined according to the Western medicine signs and the syndrome type. The Western medicine signs and the syndrome type are combined to determine the TCM medication recommendation.
[0049] In the technical solution of the embodiment, the heart and lung auscultation sound signals of the child to be diagnosed are collected, the representation of the auscultation sound in the Western medicine auxiliary examination corresponding to the auscultation sound signals is determined, and the Western medicine signs include the representation of the auscultation sound; the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound is determined; and the TCM medication recommendation for the child to be diagnosed is determined according to the Western medicine signs and / or the TCM syndrome type. Through the relationship between the Western medicine signs and the TCM syndrome type, the syndrome type corresponding to the auscultation sound signals and the TCM medication recommendation are quickly diagnosed and determined, and the diagnosis speed of the child pneumonia and the timeliness of the treatment are improved.
[0050] Based on any of the above embodiments of the present application, in the second embodiment of the present application, the same or similar contents as the above embodiments can be referred to the above introduction, and will not be described in detail. On this basis, please refer to Figure 2 , step S10 further includes: Step S11, extracting signal features of the auscultation sound signals, the signal features including at least one of time domain features, frequency domain features, time-frequency features and perception features; Step S12, determining the Western medicine signs according to the signal features, the Western medicine signs including at least one of the representation of the auscultation sound, at least one of fine moist rales, coarse moist rales, wheezing sound, weakened or disappeared breathing sound, and tubular breathing sound.
[0051] In the embodiment, the time-domain features include at least one of an amplitude envelope, a zero-crossing rate, an energy, a root mean square energy, a peak amplitude, and an autocorrelation function; the frequency-domain features include at least one of a spectral centroid, a spectral bandwidth, a spectral spread, a spectral flatness, a spectral rolloff point, a spectral flux, a mel-frequency cepstral coefficient, a chroma feature, and a level profile feature; the time-frequency features include at least one of a spectrogram, a constant-Q transform, and a wavelet transform coefficient; and the perceptual features include at least one of a loudness, a pitch, and a timbre.
[0052] Optionally, the signal features further include high-level features and feature combinations, wherein the high-level features include a fundamental frequency and a harmonic structure, a feature statistic, a feature difference, and a feature combination thereof.
[0053] The generation of wet rales is related to secretions in the trachea, bronchus or bronchiole lumen. By accurately analyzing the auscultation sound signal features, the position of the wet rales can be determined, such as the position of the large and small water bubble sounds in the airway, and the number and nature of the wet rales, such as continuous or intermittent. For wheezing sounds, it can also be accurately judged whether it occurs in the expiratory phase or the inspiratory phase, and whether it is a high or low pitch wheezing sound, which is of great significance for the diagnosis of diseases such as bronchial asthma and asthmatic bronchitis.
[0054] Optionally, based on the acquired auscultation sound signal, an auscultation sound signal data set is obtained; the auscultation sound signal data set is normalized and signal denoised to obtain preprocessed auscultation sound signal data; the preprocessed auscultation sound signal data is feature extracted to determine the signal features of the auscultation sound signal data, including a mel frequency, and based on the mel frequency, a cepstrum analysis is performed to obtain a mel cepstrum coefficient of the auscultation sound signal. The mel frequency is a frequency scale related to the auditory characteristics of the human ear. By performing mel frequency analysis on the respiratory sound data, the human auditory system can better simulate the way of perceiving sound. This helps to highlight the frequency range of the disease-related feature components in the auscultation sound signal, such as the frequency range of abnormal sounds such as wet rales and wheezing, and provides a more meaningful basis for subsequent feature extraction.
[0055] Optionally, the time-domain features in the signal features include a respiratory cycle length and an abnormal sound duration ratio. The frequency-domain features in the signal features include a mel frequency cepstrum coefficient principal component and energy concentrated in a specific frequency band, such as 200-600 Hz of wet rales. Optionally, the signal features further include nonlinear features, and the nonlinear features include a sample entropy for measuring the complexity of the respiratory sound. Optionally, the auscultation sound signal analysis includes time-frequency analysis, and a short-time Fourier transform is used to locate the wet rale segment, such as 200-600 Hz.
[0056] The fine moist rale, coarse moist rale, wheezing sound, decreased, disappeared or prolonged breath sound, and tubular breath sound in the representation of the auscultation sound can be respectively determined as the description label based on the auscultation sound, such as the A-E sound characteristics in the auscultation sound determined through training and feature analysis, so as to bind the A sound characteristic as the fine moist rale, the B sound characteristic as the coarse moist rale, the C sound characteristic as the wheezing sound, the D sound characteristic as the breath sound, and the E sound characteristic as the tubular breath sound. Of course, the binding can also be based on other rules, which is not limited herein.
[0057] In an embodiment, a general parameter model of cardiopulmonary sound auscultation (Western medicine) and four diagnostic methods (TCM) is established, such as the program of the data processing model: def preprocess_integrated_data(audio_data, tcm_data, patient_info): Input according to ISO 23961 (TCM) and ISO 13485 (Western medicine equipment) standards: audio_data: heart / lung time domain signal (sampling rate ≥ 44 kHz) tcm_data: four diagnostic data (tongue map / pulse / witness diagnosis / interrogation) patient_info: patient basic information (including region, race) Output: standardized feature matrix Among them, the program of Western medicine heart and lung sound processing (ERS / ATS 2023 standard) is: heart_clean = adaptive_wiener_filter( audio_data['heart'], noise_profile=audio_data['env_noise'], freq_range=(20, 150)# Heart sound main frequency band ) lung_features = extract_lung_features( audio_data['lung'], min_breath_cycle=1.2,# Shortest breath cycle (s) crackle_threshold=0.35# Crackle detection threshold ) Among them, the program of TCM four diagnostic methods (ISO 23961:2023) is: Tongue diagnosis standardization tongue_std = normalize_tongue_image( tcm_data['tongue_img'], color_space='CIELAB',# ISO recommended color space roi_method='U-Net_ISO' ) Pulse diagnosis processing pulse_clean = process_pulse_wave( tcm_data['pulse'], remove_baseline=True, bandpass=(0.5, 40)# Pulse characteristic frequency band ) Among them, the program of multi-modal spatio-temporal alignment (core) is: aligned_data = dynamic_alignment({ 'heart': extract_heart_features(heart_clean), 'lung': lung_features, 'tongue': extract_tongue_features(tongue_std), 'pulse': extract_pulse_features(pulse_clean), 'symptoms': encode_symptoms(tcm_data['symptoms'])# Questionnaire text encoding }, sync_method='DTW_ECG') Among them, the program of international standard feature conversion is: return { 'western': apply_iso_transform(aligned_data['cardiopulmonary'], 'ISO_13485'), 'tcm': apply_iso_transform(aligned_data['tcm'], 'ISO_23961_2023') } Exemplary, refer to Figure 3 , Figure 3 The data fusion process provided by the present application is shown in the figure, which gives the spatial mapping of heart sound features and lung sound features to obtain western decision flow, while the results of traditional Chinese medicine four diagnostic features are spatially mapped to obtain traditional Chinese medicine decision flow, so as to internationally recognize the above western decision flow and traditional Chinese medicine decision flow, and then determine the different weight of traditional Chinese and western medicine based on different regional geographical adaptation factors, and then fuse the parameters based on different diseases such as heart failure and pneumonia, and then output the actual diagnosis disease, so as to complete the diagnosis of the disease. Exemplary, the parameter conversion rule (ISO standard mutual recognition) is shown in Table 1 as follows:
[0058] Table 1 In an embodiment, a program design method of a traditional Chinese and western medicine mutual recognition computing engine is also provided, such as: def iso_integration(western_feat, tcm_feat, patient_info): """International standard mutual recognition calculation (core)""" # 1. Western parameter standardization iso_western = { 'CR': 20 * math.log10(western_feat['S2_amp'] / western_feat['S1_amp']), 'CD': western_feat['crackle_count'] / (western_feat['rec_time'] / 60) *patient_info['BMI'] / 22 } Among them, the program of traditional Chinese medicine parameter standardization is: iso_tcm = { 'YGI': 0.28*tcm_feat['tongue_L'] + 0.72*tcm_feat['tongue_b'], 'WSI': integrate(np.abs(np.diff(tcm_feat['pulse']))), 'SYM': tcm_feat['symptom_score'] } Among them, the program of dynamic weight generation (innovation point) is: weights = get_dynamic_weights( disease=patient_info['diagnosis'], region=patient_info['region'], phase=patient_info['disease_phase']# Acute phase / chronic phase ) The procedure for generating internationally recognized parameters is as follows: return { 'Global_Heart_Lung_Index': weights['western']*iso_western['CR']+ weights['tcm']*iso_tcm['WSI'], 'Syndrome_Risk_Score': iso_tcm['YGI'] * (0.5 + 0.05*patient_info['age'] / 30) +0.3*iso_tcm['SYM'] } For example, the procedure for the verification method (quadruple gold standard) can be: def quad_validation(iso_output, patient_info): "International Quadruple Metal Standard Verification System" Western medical equipment verification: western_val = { 'vs_echo': pearsonr(iso_output['CR'], echo_ef), 'vs_CT': accuracy(iso_output['CD'], ct_score) } Verified by Traditional Chinese Medicine experts: tcm_val = { 'kappa_global': cohen_kappa( iso_output['Syndrome_Risk_Score'], [cn_expert, eu_expert]# Experts from multiple countries )} International Standard Compliance: iso_val = { 'traceability_error': check_iso_compliance(iso_output), 'terminology_match': match_iso_terms(iso_output) } Clinical Endpoint Validation (Hard Endpoints): clinical_val = { 'mortality_auc': roc_auc_score(iso_output['Risk_Score'], mortality_30d), 'hosp_days_corr': spearmanr(iso_output['Score'], hospital_days) } return {**western_val, **tcm_val, **iso_val, **clinical_val} Further, the template quantity and template index are described by the following formula (1) and Table 2: (1) Wherein, Kregion is regional stratification, such as Asia / Europe / America≥100 cases per layer, Kdisease is disease stratification, such as heart failure / pneumonia / chronic obstructive pulmonary disease≥50 cases per layer, and the minimum sample size≥600 cases.
[0059]
[0060] Table 2 For example, the pseudo code implementation (international mutual recognition core) is as follows: def global_reconciliation(features, patient_info): "International Standard Mutual Recognition Calculation Engine" Feature Standardization (ISO Conversion): western_iso = transform_to_iso(features['western'], '13485') tcm_iso = transform_to_iso(features['tcm'], '23961') Dynamic weight generation (core) weight_table = { 'HF': {'western': 0.7, 'tcm': 0.3},# heart failure 'PN': {'western': 0.4, 'tcm': 0.6},# pneumonia 'COPD': {'western': 0.5, 'tcm': 0.5} } weights = adjust_for_region( base_weights=weight_table[patient_info['diagnosis']], region=patient_info['region'] ) Generate reconciled parameters reconciled_params = { 'CardioTCM_Index': weights['western'] * western_iso['CR']+ weights['tcm'] * tcm_iso['WSI'], 'Global_Syndrome_Score': tcm_iso['YGI'] * symptom_amplifier(patient_info['symptoms']) } Output in ISO standard format return format_as_iso(reconciled_params, version="2025") For example, there are the following differences for users in different regions in Table 3:
[0061] Table 3 In the technical solution of this embodiment, by extracting the features of the auscultation sound signal, the audio of the heart and lungs is analyzed from multiple dimensions, which improves the accuracy and comprehensiveness of the determination of Western medicine signs. Based on the signal features, Western medicine signs such as moist rales, breath sounds and wheezing can be determined more accurately, so as to facilitate the subsequent diagnosis and classification of children to be diagnosed.
[0062] Based on any of the above embodiments of this application, in the third embodiment of this application, the same or similar content as the above embodiments can be referred to the above description, and will not be repeated hereafter. Based on this, please refer to... Figure 4 Step S20 also includes: Step S21: Based on at least one of the fine moist rales, the coarse moist rales, the wheezing, the weakened or absent breath sounds, and the tubular breath sounds, determine the TCM syndrome type in the TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds.
[0063] Optionally, when dense fine moist rales are present, accompanied by coarse moist rales, and changes in breath sounds, including increases or decreases in breath sounds, the TCM syndrome type is determined to be phlegm-heat obstructing the lungs syndrome. Optionally, when dense fine moist rales are present within a predetermined lung area, along with tubular breath sounds and decreased breath sounds, the TCM syndrome type is determined to be toxic-heat obstructing the lungs syndrome. Optionally, when coarse breath sounds are present in the early stage and moist rales are present in the later stage, the TCM syndrome type is determined to be wind-cold obstructing the lungs syndrome. Optionally, when coarse breath sounds are present, along with dense moist rales and wheezing, the TCM syndrome type is determined to be wind-heat obstructing the lungs syndrome. Optionally, when moist rales decrease or disappear, and breath sounds are normal, the TCM syndrome type is determined to be yin deficiency with lung heat syndrome. Optionally, when there are no rales or occasional moist rales, and breath sounds are normal or slightly weak, the TCM syndrome type is determined to be lung and spleen qi deficiency syndrome.
[0064] In Traditional Chinese Medicine (TCM) diagnosis and treatment, auscultatory sounds serve as an auxiliary diagnostic tool. These sounds are crucial evidence for determining key pathogenic factors such as phlegm, heat, obstruction, and wheezing. For example, moist rales suggest phlegm turbidity, while wheezing indicates qi stagnation and phlegm obstruction.
[0065] In an optional embodiment, other TCM data is acquired, including observation data, auscultation data, and palpation data. Auscultation data includes sounds heard and smells detected by the doctor. Based on at least one of moist rales, breath sounds, and wheezing sounds, as well as other TCM data, the syndrome type in TCM syndrome differentiation corresponding to Western medicine signs is determined.
[0066] Traditional Chinese medicine auscultation includes listening to sound and smell. Among them, the sound includes coughing sound, breathing sound, phlegm sound, crying sound, language sound, etc. The ancient Chinese medical books describe that the throat water chicken sound is similar to wheezing sound, the murmur sound is similar to moist rale, and the shortness of breath is directly corresponding to the modern auscultation findings of wheezing sound, moist rale and shortness of breath. In modern pediatric clinical practice of traditional Chinese medicine, lung auscultation has become an indispensable extension and refinement of traditional Chinese medicine auscultation, and is an important embodiment of the objectification of traditional Chinese medicine four diagnoses. Doctors will include the auscultation results in the category of auscultation as an important objective basis for diagnosis.
[0067] Optionally, the auscultation sound includes dense fine moist rales, possibly accompanied by coarse moist rales, and the respiratory sound may be enhanced or weakened, and if accompanied by airway spasm, wheezing sound may be present. Other traditional Chinese medicine data include: high fever, severe cough, yellow and thick sputum or phlegm sound in the throat, shortness of breath, red face, dry mouth, red throat, red tongue with yellow and greasy fur, slippery and rapid pulse, and purple and sluggish fingerprints. At this time, the moist rale directly corresponds to the pathogenesis of phlegm heat accumulation, and the auscultation sound corresponds to the phlegm heat closing lung syndrome.
[0068] Optionally, the auscultation sound includes auscultation signs that are often more obvious and extensive, dense fine moist rales, tubular breathing sound, and weakened respiratory sound, which may be caused by severe inflammation and exudation. When the condition is critical, the auscultation may be atypical. Other traditional Chinese medicine data include high fever that does not subside, severe cough, severe wheezing, restlessness or mental debilitation, cyanotic lips, deep red or purple tongue, yellow and thick fur or little fur without saliva, rapid and fine pulse, and purple and dark fingerprints to the point of death. The extensive moist rales and consolidation signs reflect the severe pathogenesis of heat-toxicity, lung collateral obstruction, and sputum formation from the burning of saliva. At this time, the auscultation sound corresponds to the phlegm heat closing lung syndrome.
[0069] It should be noted that the enhancement or weakening or disappearance of the respiratory sound is in relation to the sound intensity of normal respiratory sound. The enhancement of respiratory sound is higher than the sound intensity of normal respiratory sound, and the weakening or disappearance of respiratory sound is lower than the sound intensity of normal respiratory sound.
[0070] Optionally, the auscultation sound includes early stage may have no abnormality or only rough breathing sound. With the progression of the disease, scattered moist rales may appear after sputum is generated. Other traditional Chinese medicine data include cold with high fever, light, no sweating, heavy coughing sound, thin and white sputum that is easy to cough, and later may turn yellow, nasal congestion with clear nasal discharge, dry mouth, no red throat, pale red tongue with thin white fur, tight pulse, and floating red fingerprints. Early stage auscultation negative or rough sound reflects cold binding the lung and lung qi failing to disperse. Later stage moist rales suggest that cold evil enters the interior and generates heat and sputum or cold sputum blocks the lung. At this time, the auscultation sound corresponds to the wind-cold closing lung syndrome.
[0071] Optionally, the auscultation sound includes early rough respiratory sound, faster appearing scattered or more intensive moist rales, and possibly wheezing sound if airway is highly reactive. Other TCM data include heavy fever with aversion to cold, sweating, cough with yellow and sticky sputum, nasal obstruction with yellow nasal discharge, thirst with red and sore throat, red and thin yellowish tongue fur on the edge of the tongue, floating and uneven pulse, and pale and purple finger print. Moist rales reflect the pathogenic wind-heat burning body fluid into phlegm, and blocking the airway. At this time, the auscultation sound corresponds to wind-heat closing lung syndrome.
[0072] Optionally, the auscultation sound includes reduced or disappeared moist rales, or only a few scattered moist rales, and the respiratory sound can be basically normal. Other TCM data include low fever or irregular fever, dry cough without sputum or with little sputum, dry mouth and throat, hot hands and feet, night sweat, flushed face, red tongue with little fluid and little or peeled tongue fur, thin and rapid pulse, and pale and purple finger print. The auscultation sound indicates that the phlegm gradually disappears, but the internal heat of yin deficiency is not cleared. At this time, the auscultation sound corresponds to yin deficiency and lung heat syndrome, which is often seen in the recovery or protracted period of pneumonia.
[0073] Optionally, the auscultation sound includes usually no rales or only a few and rare moist rales, and the respiratory sound can be normal or slightly weak. Other TCM data include weak cough, white and thin sputum, shortness of breath, lazy speech, sweating when moving, loss of appetite, pale complexion, loose and thin stool, pale and swollen tongue with white and slippery fur, thin and weak pulse, and pale finger print. A small amount of thin rales or weak respiratory sound reflects lung and spleen qi deficiency, and weak transportation and transformation, with remaining phlegm not cleared or phlegm wetness generated internally. At this time, the auscultation sound corresponds to lung and spleen qi deficiency syndrome, which is often seen in the recovery or protracted period of pneumonia.
[0074] In the technical solution of the present embodiment, different syndrome types differ in the manifestations of moist rales, respiratory sound and wheezing sound. Western medical signs provide quantifiable indicators and objective basis for TCM differentiation, while TCM differentiation provides holistic concept and syndrome differentiation and treatment ideas for western medical treatment, which helps to break the discipline barriers between TCM and western medicine, and improve the accuracy and speed of pneumonia diagnosis.
[0075] Based on any of the above embodiments of the present application, in the fourth embodiment of the present application, the same or similar contents as the above embodiments can be referred to the above introduction, and will not be described hereinafter. On this basis, please refer to Figure 5 , step S30 further comprises: Step S31, when the western medical sign and / or the TCM syndrome type corresponds to moist rales, it is determined that the TCM medication recommendation includes phlegm-removing Chinese medicine; Step S32, when the western medical sign and / or the TCM syndrome type corresponds to wheezing sound, it is determined that the TCM medication recommendation includes Chinese medicine for relieving asthma and opening lung, and for reducing qi and removing phlegm; Step S33, when the western medical sign and / or the TCM syndrome type corresponds to weakened respiratory sound or tubular respiratory sound, it is determined that the TCM medication recommendation includes Chinese medicine for promoting lung and opening blockage, and for clearing heat and removing toxin; Step S34, when the Western medicine signs and / or the TCM syndrome type correspond to the disappearance of the recovery period auscultation sound, it is determined that the TCM medication recommendation includes TCMs for nourishing yin and clearing lung or for invigorating spleen and supplementing lung.
[0076] In this embodiment, the auscultation sound of pediatric pneumonia is the key sign for Western medicine diagnosis of pneumonia, especially fine moist rales and wheezing sound. In the perspective of TCM, these auscultation sounds are an important part of auscultation, which directly reflects the core pathogenesis of phlegm, heat, obstruction and asthma. The auscultation sound provides strong objective evidence and quantitative reference for TCM syndrome differentiation and typing.
[0077] In the diagnosis and treatment of pediatric pneumonia, TCM highly depends on and integrates the results of auscultation, which is one of the key bases for syndrome differentiation, prescription selection, especially the selection of phlegm-eliminating and asthma-relieving drugs, and the evaluation of efficacy and prognosis.
[0078] Optionally, when there are obvious moist rales, i.e. phlegm obstruction, the application of phlegm-eliminating drugs will be strengthened, such as Banxia, Chenpi, Fuling, Gualoupi, Danshanxi and Zhulai. Optionally, when there are wheezing sounds, i.e. qi obstruction and phlegm obstruction, the application of drugs for relieving asthma, opening lung and reducing qi and phlegm will be emphasized, such as Mahuang, Xingren, Tingshizi, Suzi, Qianhu, Dilong, etc. Optionally, when there are extensive consolidation signs and decreased / pipe-shaped breath sounds, it indicates that the lung obstruction is serious, and the drugs for promoting lung and clearing heat and detoxifying should be used more, such as Mahuangxingshigan Decoction plus heat-clearing and detoxifying drugs. Optionally, when the auscultation sound disappears or basically disappears in the recovery period, the treatment focus shifts to nourishing yin and clearing lung or invigorating spleen and supplementing lung.
[0079] In an optional embodiment, after step S30, it further includes: during the treatment process, reacquiring a new auscultation sound signal of the pediatric patient to be diagnosed; determining a new Western medicine sign corresponding to the new auscultation sound signal; determining the sign change between the Western medicine sign before the treatment and the new Western medicine sign, the sign change including the changed sign and the changed degree; determining the severity of the disease and the recovery condition of the pediatric patient to be diagnosed according to the sign change, the severity of the disease and the recovery condition being used to prompt whether the TCM medication recommendation needs to be adjusted.
[0080] It should be noted that the reduction, narrowing of the range, and decrease in density of moist rales, and the alleviation or disappearance of wheezing sound during the treatment process are important objective indicators for judging whether the TCM and the overall treatment are effective, whether the phlegm-heat is subsided, and whether the lung obstruction is opened. On the contrary, if the auscultation sound persists or worsens, it indicates that the treatment plan needs to be adjusted. According to the duration and severity of the auscultation sound, combined with other indicators, it is helpful to judge the severity of the disease and the recovery condition.
[0081] During the treatment process, by reacquiring new auscultation signals and determining new Western medicine signs, the subtle changes in the condition of children can be understood in a timely and dynamic manner. This helps doctors to grasp the development trend of the disease in real time, avoid misjudgment or delay treatment due to hidden changes in the condition, and determine whether to adjust the TCM medication recommendation according to the changes in the signs, making the treatment more targeted and timely. This avoids unnecessary or inappropriate use of drugs, improves treatment effectiveness, and reduces the pain and economic burden of patients. The combination of Western medicine sign monitoring and TCM syndrome differentiation treatment fully utilizes the advantages of both. Through the changes in signs, the adjustment of TCM medication is guided, making the combination of TCM and Western medicine treatment more closely and coordinated, and improving the overall treatment effect.
[0082] In the technical solution in this embodiment, according to different Western medicine signs and TCM syndrome types, the corresponding TCM medication recommendation is accurately matched, and through accurate drug treatment, the symptoms can be effectively relieved, the disease progression can be controlled, the disease course can be shortened, and the children patients can recover faster, reducing the damage of the disease to the body. The medication strategies for different disease stages and different signs are covered, from reducing phlegm, relieving asthma, and promoting lung to restoring the lung and spleen, forming a complete treatment system that can improve the lung function of patients and promote the improvement of the disease.
[0083] Based on any of the above embodiments of the present application, in the fifth embodiment of the present application, the same or similar contents as the above embodiments can be referred to the above introduction, and will not be described in detail. On this basis, please refer to Figure 6 , before step S20, further comprising: Step S40, acquiring type information of children with pneumonia, the type information comprising at least one of age and disease course stage; Step S50, according to the type information, dividing the children with pneumonia into at least one preset group, and collecting audio reference signals of the heart and lung of the children with pneumonia in the preset group, and determining reference characteristics of the auscultation sound corresponding to the audio reference signals; Step S60, determining the reference type of the TCM syndrome differentiation type corresponding to the reference characteristics of the auscultation sound, and establishing the association between the reference characteristics of the auscultation sound and the reference type of the TCM syndrome differentiation type; Step S20 comprises: Step S22, according to the association, determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the characteristics of the auscultation sound of the child to be diagnosed.
[0084] Optionally, by grouping the medical diagnosis data of pediatric pneumonia patients according to one or more of the type information such as age, pathogen type, and course stage, the pediatric pneumonia patients with different characteristics can be analyzed hierarchically. This helps doctors more accurately grasp the disease characteristics and disease regularity of different pediatric pneumonia patient groups, thereby improving the pertinence and accuracy of diagnosis.
[0085] It should be noted that the pathogen type includes bacterial, viral, atypical pathogen, fungal, etc. For example, the bacterial includes Streptococcus pneumoniae, Staphylococcus aureus, etc., the viral includes influenza virus, respiratory syncytial virus, human metapneumovirus, etc., the atypical pathogen includes mycoplasma pneumonia, chlamydia pneumonia, etc., and the fungal includes aspergillus, candida, etc. The course stage of pneumonia can be divided into multiple stages according to pathophysiological changes, clinical manifestations, and treatment response, and the course characteristics of different pathogen types are different.
[0086] In the technical solution of the embodiment, the pediatric pneumonia patients are grouped according to the type information such as age and course stage, the characteristics and differences of different types of patients are fully considered, and through grouping analysis, a more accurate correlation can be established according to the characteristics of different pediatric pneumonia patients, thereby improving the accuracy of diagnosis.
[0087] It should be noted that the above examples are only used to understand the present application and do not limit the association method of pediatric pneumonia auscultation sound and TCM diagnosis data of the present application. More simple transformations based on this technical concept are within the protection scope of the present application.
[0088] The present application provides an auscultation device, which comprises at least one processor and a memory in communication connection with the at least one processor. The memory stores instructions executable by the at least one processor, and the instructions are executed by the at least one processor to enable the at least one processor to perform the association method of pediatric pneumonia auscultation sound and TCM diagnosis data in the above-mentioned embodiment one.
[0089] In an optional embodiment, the auscultation device comprises an audio acquisition module, a memory, a processor, and an association program of pediatric pneumonia auscultation sound and TCM diagnosis data stored on the memory and executable on the processor. The association program of pediatric pneumonia auscultation sound and TCM diagnosis data is executed by the processor to perform the following steps: Acquire the heart and lung auscultation sound signal of the pediatric patient to be diagnosed, determine the representation of the auscultation sound in the western medical auxiliary examination corresponding to the auscultation sound signal, and the western medical sign includes the representation of the auscultation sound; Determine the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound; According to the western medical sign and / or the TCM syndrome type, determine the TCM medication recommendation for the pediatric patient to be diagnosed.
[0090] In an optional embodiment, when the processor invokes the program for associating the auscultation sound of children's pneumonia and the TCM diagnosis data stored in the memory, the processor further performs the following steps: extracting signal features of the auscultation sound signal, the signal features including at least one of time domain features, frequency domain features, time-frequency features and perceptual features; the time domain features including at least one of amplitude envelope, zero-crossing rate, energy, root mean square energy, peak amplitude, autocorrelation function; the frequency domain features including at least one of spectral centroid, spectral bandwidth, spectral spread, spectral flatness, spectral roll-off point, spectral flux, mel-frequency cepstral coefficient, chroma features, level contour features; the time-frequency features including at least one of spectrogram, constant Q transform, wavelet transform coefficient; the perceptual features including at least one of loudness, pitch, timbre; determining the western medical signs according to the signal features, the western medical signs including at least one of representation of the auscultation sound, fine moist rales, coarse moist rales, wheezing sound, weakened or disappeared breath sound, tubular breath sound.
[0091] In an optional embodiment, when the processor invokes the program for associating the auscultation sound of children's pneumonia and the TCM diagnosis data stored in the memory, the processor further performs the following steps: determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared breath sound, the tubular breath sound.
[0092] In an optional embodiment, when the processor invokes the program for associating the auscultation sound of children's pneumonia and the TCM diagnosis data stored in the memory, the processor further performs the following steps: when there are dense fine moist rales accompanied by coarse moist rales, and accompanied by breath sound changes, determining that the TCM syndrome type is phlegm-heat obstructing lung syndrome.
[0093] when there are dense fine moist rales in a preset lung range, and there are tubular breath sound and weakened breath sound, determining that the TCM syndrome type is toxic heat obstructing lung syndrome; when there are coarse breath sounds in the early stage and wet rales in the later stage, determining that the TCM syndrome type is wind-cold obstructing lung syndrome; when there are coarse breath sounds, dense wet rales and wheezing sound, determining that the TCM syndrome type is wind-heat obstructing lung syndrome; when the wet rales are reduced or disappeared, and the breath sound is normal, determining that the TCM syndrome type is yin deficiency and lung heat syndrome; when there are no rales or occasional wet rales, and the breath sound is normal, determining that the TCM syndrome type is lung and spleen qi deficiency syndrome.
[0094] In an optional embodiment, when the processor invokes the program for associating the auscultation sound of children's pneumonia with the TCM diagnosis data stored in the memory, the processor further performs the following steps: obtaining other TCM data, the other TCM data including inspection data, auscultation data and palpation data, the auscultation data including sounds heard by the doctor and smells smelled by the doctor; determining a syndrome type in the TCM syndrome differentiation type corresponding to the Western medical sign according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared breath sound, the tubular breath sound, and the other TCM data.
[0095] In an optional embodiment, when the processor invokes the program for associating the auscultation sound of children's pneumonia with the TCM diagnosis data stored in the memory, the processor further performs the following steps: when the Western medical sign and / or the TCM syndrome type corresponds to moist rales, determining that the TCM medication recommendation includes TCM drugs for reducing phlegm; when the Western medical sign and / or the TCM syndrome type corresponds to wheezing sound, determining that the TCM medication recommendation includes TCM drugs for relieving asthma, opening the lung and reducing phlegm; when the Western medical sign and / or the TCM syndrome type corresponds to weakened breath sound or tubular breath sound, determining that the TCM medication recommendation includes TCM drugs for promoting the lung and clearing heat; when the Western medical sign and / or the TCM syndrome type corresponds to disappeared auscultation sound in the recovery period, determining that the TCM medication recommendation includes TCM drugs for nourishing yin and clearing lung or for invigorating the spleen and supplementing the lung.
[0096] In an optional embodiment, when the processor invokes the program for associating the auscultation sound of children's pneumonia with the TCM diagnosis data stored in the memory, the processor further performs the following steps: re-acquiring a new auscultation sound signal of the child to be diagnosed during the treatment process; determining a new Western medical sign corresponding to the new auscultation sound signal; determining a sign change condition between the Western medical sign before the treatment and the new Western medical sign, the sign change condition including a changed sign and a changed degree; determining a severity condition and a recovery condition of the child to be diagnosed according to the sign change condition, the severity condition and the recovery condition being used to prompt whether the TCM medication recommendation needs to be adjusted.
[0097] In an optional embodiment, when the processor invokes the program for associating the auscultation sound of children's pneumonia with the TCM diagnosis data stored in the memory, the processor further performs the following steps: obtaining type information of the child pneumonia patient, the type information including at least one of age and disease course stage; According to the type information, the children pneumonia patients are divided into at least one preset group, and an audio reference signal of a heart and lung part of a children pneumonia patient in the preset group is collected to determine a reference representation of an auscultation sound corresponding to the audio reference signal; A syndrome reference type in a TCM syndrome differentiation type corresponding to the reference representation of the auscultation sound is determined, and a correlation between the reference representation of the auscultation sound and the syndrome reference type in the TCM syndrome differentiation type is established; According to the correlation, a TCM syndrome type in a TCM syndrome differentiation type corresponding to a representation of an auscultation sound of a child to be diagnosed is determined.
[0098] Reference is made below to Figure 7 which shows a structural schematic diagram of an auscultation device suitable for being used to implement embodiments of the present application. The auscultation device in the embodiments of the present application can include, but is not limited to, a terminal such as a wearable device, an electronic stethoscope, an audio collection device, etc. Figure 7 The auscultation device shown is merely an example and should not bring any limitation to the functions and use range of the embodiments of the present application.
[0099] As Figure 7 shown, the auscultation device can include a processing apparatus 1001 (for example, a central processing unit, a graphic processing unit, etc.) which can perform various appropriate actions and processes according to a program stored in a read-only memory (ROM) 1002 or a program loaded from a storage apparatus 1003 to a random access memory (RAM) 1004. In the RAM 1004, various programs and data required for operation of the auscultation device are also stored. The processing apparatus 1001, the ROM 1002, and the RAM 1004 are connected to each other through a bus 1005. An input / output (I / O) interface 1006 is also connected to the bus. Generally, the following systems can be connected to the I / O interface 1006: an input apparatus 1007 including, for example, a touch screen, a touch pad, etc.; an output apparatus 1008 including, for example, a liquid crystal display (LCD), a speaker, a vibrator, etc.; the storage apparatus 1003; and a communication apparatus 1009. The communication apparatus 1009 can allow the auscultation device to perform wireless or wired communication with other devices to exchange data. Although the auscultation device with various systems is shown in the figure, it should be understood that all the systems shown are not required to be implemented or possessed. More or fewer systems can be alternatively implemented or possessed.
[0100] In particular, according to the embodiments disclosed in the present application, the process described above with reference to the flowchart can be implemented as a computer software program. For example, the embodiments disclosed in the present application include a computer program product comprising a computer program carried on a computer readable medium, the computer program containing program codes for executing the method shown in the flowchart. In such embodiments, the computer program can be downloaded and installed from a network through a communication device, or installed from the storage device 1003, or installed from the ROM 1002. When the computer program is executed by the processing device 1001, the above-mentioned functions defined in the method of the embodiments disclosed in the present application are executed.
[0101] The auscultation device provided by the present application adopts the association method of pediatric pneumonia auscultation sound and TCM diagnosis data in the above-mentioned embodiments, which can solve the technical problem of low pediatric pneumonia diagnosis speed. Compared with the prior art, the auscultation device provided by the present application has the same beneficial effects as the association method of pediatric pneumonia auscultation sound and TCM diagnosis data provided by the above-mentioned embodiments, and other technical features in the auscultation device are the same as the features disclosed in the previous embodiment method, which will not be repeated here.
[0102] It should be understood that various parts of the present application can be realized by hardware, software, firmware or a combination thereof. In the description of the above-mentioned embodiments, specific features, structures, materials or characteristics can be combined in any one or more embodiments or examples in a suitable manner.
[0103] The above is merely specific implementation of the present application, but the protection scope of the present application is not limited thereto, any person skilled in the art can easily think of changes or replacements within the technical scope disclosed in the present application, which should be covered in the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.
[0104] The present application provides a computer readable storage medium having stored thereon computer readable program instructions (i.e. computer program) for executing the association method of pediatric pneumonia auscultation sound and TCM diagnosis data in the above-mentioned embodiments.
[0105] The computer readable storage medium provided in the application may be, for example, a U disk, but is not limited to an electric, magnetic, optical, electromagnetic, infrared, or semiconductor system or device, or any combination thereof. More specific examples of the computer readable storage medium may include, but are not limited to, an electric connection with one or more conductive wires, a portable computer disk, a hard disk, a random access memory (RAM), a read only memory (ROM), an erasable programmable read only memory (EPROM or flash memory), an optical fiber, a portable compact disk read only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination thereof. In the embodiment, the computer readable storage medium may be any tangible medium containing or storing a program that can be used by or in combination with an instruction execution system, system, or device. The program code contained on the computer readable storage medium can be transmitted by any suitable medium, including but not limited to an electric wire, an optical cable, a radio frequency (RF), and the like, or any suitable combination thereof.
[0106] The computer readable storage medium described above may be contained in the auscultation device, or may exist separately without being assembled into the auscultation device.
[0107] The computer readable storage medium described above carries one or more programs, which, when executed by the auscultation device, cause the auscultation device to: provide strong objective evidence and quantitative reference for TCM syndrome differentiation (especially excess syndromes such as phlegm-heat obstructing lung and toxic-heat obstructing lung) by the relationship between Western medical signs and TCM syndrome types. In the diagnosis and treatment of pediatric pneumonia, TCM highly depends on and integrates the auscultation results, which are used as key basis for syndrome differentiation, prescription selection (especially the selection of phlegm-heat relieving and panting relieving drugs), and evaluation of curative effect and prognosis. At the same time, through the relationship between Western medical signs and TCM syndrome types, the corresponding syndrome type and TCM drug recommendation of the auscultation sound signal are quickly diagnosed and determined, which improves the diagnosis speed and timeliness of treatment of pediatric pneumonia.
[0108] Computer program code for carrying out operations of the present application can be written in any combination of one or more programming languages, including an object oriented programming language such as Java, Smalltalk, C++ or the like and conventional procedural programming languages, such as the "C" programming language or similar programming languages. The program code can execute entirely on the user's computer, partly on the user's computer, as a stand-alone software package, partly on the user's computer and partly on a remote computer or entirely on the remote computer or server. In the latter scenario, the remote computer can be connected to the user's computer through any type of network, including a local area network (LAN) or a wide area network (WAN), or the connection can be made to an external computer (for example, through the Internet using an Internet Service Provider).
[0109] The computer program instructions can also be loaded onto a computer or other programmable information processing apparatus to cause a series of operations to be performed on the computer or other programmable information processing apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable information processing apparatus implement the functions / acts specified in the flowchart and / or block diagram block or blocks.
[0110] The modules involved in the embodiments of the present application can be implemented by software or by hardware. In some cases, the name of the module does not constitute a limitation on the module itself.
[0111] The readable storage medium provided by the application is a computer readable storage medium, and the computer readable storage medium stores computer readable program instructions (i.e. computer programs) for executing the above-mentioned method for associating auscultation sound of children's pneumonia and TCM diagnosis data, and can solve the technical problem of low diagnosis speed of children's pneumonia. Compared with the prior art, the computer readable storage medium provided by the application has the same beneficial effects as the method for associating auscultation sound of children's pneumonia and TCM diagnosis data provided by the above-mentioned embodiments, and will not be repeated here.
[0112] The application further provides a computer program product comprising a computer program, which, when executed by a processor, implements the steps of the method for associating auscultation sound of children's pneumonia and TCM diagnosis data as described above.
[0113] The computer program product provided by the application can solve the technical problem of low diagnosis speed of children's pneumonia. Compared with the prior art, the computer program product provided by the application has the same beneficial effects as the method for associating auscultation sound of children's pneumonia and TCM diagnosis data provided by the above-mentioned embodiments, and will not be repeated here.
[0114] The above-mentioned is only part of the embodiments of the application, and does not limit the patent scope of the application, and any equivalent structural transformation, direct / indirect application in other related technical fields made by using the content of the application specification and drawings under the technical concept of the application are included in the patent protection scope of the application.
Claims
1. A method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data, characterized in that, The method includes: Collect auscultation sounds from the heart and lungs of the child to be diagnosed, and determine the characteristics of auscultation sounds in Western medicine auxiliary examinations corresponding to the auscultation sounds. Western medicine signs include the characteristics of auscultation sounds. To determine the TCM syndrome type in the TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds; Based on the Western medicine signs and / or the TCM syndrome types, TCM medication recommendations are determined for the children to be diagnosed.
2. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 1, characterized in that, The steps for determining the representation of auscultatory sounds in Western medicine auxiliary examinations corresponding to the auscultatory sound signals include: The signal features of the auscultation sound signal are extracted, and the signal features include at least one of time-domain features, frequency-domain features, time-frequency features, and perceptual features; the time-domain features include at least one of amplitude envelope, zero-crossing rate, energy, root mean square energy, peak amplitude, and autocorrelation function; the frequency-domain features include at least one of spectral centroid, spectral bandwidth, spectral spread, spectral flatness, spectral roll-off point, spectral flux, Mel-frequency cepstral coefficients, chromaticity features, and pitch profile features; the time-frequency features include at least one of spectrogram, constant Q-transform, and wavelet transform coefficients; the perceptual features include at least one of loudness, pitch, and timbre. The Western medicine signs are determined based on the signal characteristics, and the Western medicine signs include at least one of the following characteristics of the auscultation sounds: fine moist rales, coarse moist rales, wheezing, decreased or absent breath sounds, and tubular breath sounds.
3. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 2, characterized in that, The steps for determining the TCM syndrome type in TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds include: Based on at least one of the fine moist rales, the coarse moist rales, the wheezing, the decreased or absent breath sounds, and the tubular breath sounds, the TCM syndrome type in the TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds is determined.
4. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 3, characterized in that, The step of determining the TCM syndrome type in the TCM syndrome differentiation based on at least one of the following: fine moist rales, coarse moist rales, wheezing, decreased or absent breath sounds, and tubular breath sounds includes: When dense fine moist rales are present, accompanied by coarse moist rales, and changes in breath sounds are present, the TCM syndrome type is determined to be phlegm-heat obstructing the lungs syndrome. When there are dense fine moist rales within a preset lung area, and tubular breath sounds and decreased breath sounds are present, the TCM syndrome type is determined to be toxic heat obstructing the lungs syndrome. When coarse breath sounds are present in the early stage and moist rales are present in the later stage, the TCM syndrome type is determined to be wind-cold obstructing the lungs syndrome. When coarse breathing sounds, dense moist rales and wheezing are present, the TCM syndrome type is determined to be wind-heat obstructing the lungs syndrome. When the moist rales decrease or disappear, and the breath sounds are normal, the TCM syndrome type is determined to be Yin deficiency and lung heat syndrome. When there are no rales or only occasional moist rales, and the breath sounds are normal, the TCM syndrome type is determined to be lung and spleen qi deficiency syndrome.
5. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 3, characterized in that, The step of determining the TCM syndrome type in the TCM syndrome differentiation based on at least one of the following: fine moist rales, coarse moist rales, wheezing, decreased or absent breath sounds, and tubular breath sounds includes: Acquire other TCM data, including observation data, auscultation data, and palpation data, wherein the auscultation data includes the sounds heard and the smells detected by the doctor; Based on at least one of the fine moist rales, the coarse moist rales, the wheezing, the decreased or absent breath sounds, the tubular breath sounds, and other TCM data, the syndrome type in the TCM syndrome differentiation corresponding to the Western medicine signs is determined.
6. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 1, characterized in that, The step of determining the recommended TCM medication for the child to be diagnosed based on the Western medicine signs and / or the TCM syndrome type includes: When the Western medicine signs and / or the TCM syndrome types correspond to moist rales, it is determined that the TCM medication recommendation includes expectorant Chinese medicine. When the Western medicine signs and / or the TCM syndrome types correspond to wheezing, the recommended TCM medications include those that relieve asthma, open the lungs, and resolve phlegm. When the Western medicine signs and / or the TCM syndrome types correspond to decreased breath sounds or tubular breath sounds, the recommended TCM medications include those that promote lung function, clear heat and detoxify. When the Western medicine signs and / or the TCM syndrome types correspond to the disappearance of auscultatory sounds during the recovery period, it is determined that the recommended TCM medications include those that nourish Yin and clear the lungs or strengthen the spleen and replenish the lungs.
7. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 6, characterized in that, After the step of determining the recommended TCM medication for the child to be diagnosed based on the Western medicine signs and / or the TCM syndrome type, the method further includes: During the treatment process, new auscultation signals are reacquired from the child to be diagnosed; Identify new Western medical signs corresponding to the new auscultation sound signals; Determine the changes in physical signs between the pre-treatment Western medical signs and the new Western medical signs, including the changed signs and the degree of change; The severity and recovery status of the child's condition are determined based on the changes in the physical signs. The severity and recovery status are used to indicate whether the recommended traditional Chinese medicine medication needs to be adjusted.
8. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 1, characterized in that, Before the step of determining the TCM syndrome type in TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds, the method further includes: Obtain the type information of pediatric pneumonia patients, wherein the type information includes at least one of age and disease stage; Based on the type information, the pediatric pneumonia patients are divided into at least one preset group, and audio reference signals of the cardiopulmonary system of the pediatric pneumonia patients in the preset group are collected to determine the reference representation of the auscultation sound corresponding to the audio reference signal. Determine the syndrome reference type in the TCM syndrome differentiation corresponding to the reference representation of the auscultatory sounds, and establish the correlation between the reference representation of the auscultatory sounds and the syndrome reference type in the TCM syndrome differentiation. The steps for determining the TCM syndrome type in TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds include: Based on the aforementioned correlation, the TCM syndrome type corresponding to the auscultatory sounds of the child to be diagnosed is determined in the TCM syndrome differentiation.
9. A stethoscope device, characterized in that, The auscultation device includes: a memory, a processor, and a computer program stored in the memory and executable on the processor, the computer program being configured to implement the steps of the method for associating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in any one of claims 1 to 8.
10. A storage medium, characterized in that, The storage medium is a computer-readable storage medium, and a computer program is stored on the storage medium. When the computer program is executed by a processor, it implements the steps of the method for associating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in any one of claims 1 to 8.
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