Method, device and storage medium for associating auscultation sound of children's pneumonia with data of traditional chinese medicine diagnosis

Abstract

The application discloses a kind of children's pneumonia auscultation sound and traditional Chinese medicine diagnosis data's association method, equipment and storage medium, it is related to data processing technical field, the method comprises the following steps: collecting the heart-lung part of the child to be diagnosed auscultation sound signal, determine the representation of the auscultation sound in the western medicine auxiliary examination corresponding to the auscultation sound signal, western medicine sign includes the representation of auscultation sound;Determine the traditional Chinese medical syndrome type in the traditional Chinese medical syndrome differentiation type corresponding to the representation of the auscultation sound;According to the western medicine sign and / or the traditional Chinese medical syndrome type, determine the traditional Chinese medicine medicine recommendation of the child to be diagnosed.The application improves the diagnosis speed of children's pneumonia, provides objective basis for traditional Chinese medicine diagnosis simultaneously, establishes the correlation parameter between traditional Chinese medicine and western medicine, provides relevant basis for the combined diagnosis and medication of traditional Chinese medicine and western medicine.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of data processing, in particular to a method, device and storage medium for associating auscultation sound of pediatric pneumonia with TCM diagnosis data. BACKGROUND

[0002] Auscultation sound (especially fine moist rales and wheezing sound) of pediatric pneumonia is one of the key signs for Western medicine to diagnose pneumonia. In the perspective of traditional Chinese medicine (TCM), these auscultation sounds are an important part of "listening diagnosis" and directly reflect the core pathogenesis such as "phlegm, heat, obstruction and wheezing". Auscultation sound provides strong objective evidence and quantitative reference for TCM syndrome differentiation (especially phlegm-heat obstructing lung and toxic heat obstructing lung). When treating pediatric pneumonia, TCM highly depends on and integrates the results of auscultation, which is one of the key bases for syndrome differentiation, prescription selection (especially the selection of phlegm-reducing and wheezing-relieving drugs), and evaluation of efficacy and prognosis.

[0003] The key of integration of traditional Chinese and Western medicine is to enrich and verify the "listening diagnosis" and syndrome differentiation of TCM by the objectivity and accuracy of Western medicine auscultation, and to improve symptoms (such as cough, wheezing and sputum) and promote lung inflammation absorption and recovery by individualized treatment according to pathogenesis (including pathogenesis reflected by auscultation) combining with the advantages of TCM holistic view and syndrome differentiation and treatment.

[0004] Therefore, in clinical practice, pediatricians with Western or TCM background will pay great attention to the results of auscultation when diagnosing and treating pediatric pneumonia. TCM practitioners will organically integrate these results into the framework of TCM four examinations, making the syndrome differentiation more accurate and the treatment more targeted. The dynamic changes of auscultation sound are also one of the important objective indicators for evaluating the effect of TCM in treating pneumonia. SUMMARY

[0005] The main purpose of the present application is to provide a method, device and storage medium for associating auscultation sound of pediatric pneumonia with TCM diagnosis data, which aims to provide strong objective evidence and quantitative reference for TCM syndrome differentiation, especially phlegm-heat obstructing lung and toxic heat obstructing lung. When treating pediatric pneumonia, TCM highly depends on and integrates the results of auscultation, which is one of the key bases for syndrome differentiation, prescription selection (especially the selection of phlegm-reducing and wheezing-relieving drugs), and evaluation of efficacy and prognosis.

[0006] To achieve the above-mentioned purpose, the present application provides a method for associating auscultation sound of pediatric pneumonia with TCM diagnosis data, which comprises:

[0007] Collecting the heart and lung auscultation sound signal of the pediatric patient to be diagnosed, determining the representation of the auscultation sound in the Western medicine auxiliary examination corresponding to the auscultation sound signal, and the Western medicine signs including the representation of the auscultation sound;

[0008] Determining the TCM syndrome type in the TCM syndrome differentiation corresponding to the representation of the auscultation sound.

[0009] determine a TCM medicine recommendation for the child to be diagnosed according to the Western medicine signs and / or the TCM syndrome type.

[0010] In an embodiment, the step of determining the representation of the auscultation sound in the Western medicine auxiliary examination corresponding to the auscultation sound signal comprises:

[0011] extracting signal features of the auscultation sound signal, the signal features comprising at least one of time domain features, frequency domain features, time-frequency features, and perceptual features; the time domain features comprising at least one of amplitude envelope, zero-crossing rate, energy, root mean square energy, peak amplitude, autocorrelation function; the frequency domain features comprising at least one of spectral centroid, spectral bandwidth, spectral spread, spectral flatness, spectral roll-off point, spectral flux, mel-frequency cepstral coefficient, chroma features, level contour features; the time-frequency features comprising at least one of spectrogram, constant-Q transform, wavelet transform coefficients; the perceptual features comprising at least one of loudness, pitch, timbre;

[0012] determining the Western medicine signs according to the signal features, the Western medicine signs comprising at least one of the representation of the auscultation sound, fine moist rales, coarse moist rales, wheezing sound, weakened or disappeared breath sound, and tubular breath sound.

[0013] In an embodiment, the step of determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound comprises:

[0014] determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared breath sound, and the tubular breath sound.

[0015] In an embodiment, the step of determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared breath sound, and the tubular breath sound comprises:

[0016] when there are dense fine moist rales accompanied by coarse moist rales, and accompanied by breath sound changes, determining the TCM syndrome type as phlegm-heat obstructing lung syndrome;

[0017] when there are dense fine moist rales in a preset lung range, and there are tubular breath sound and weakened breath sound, determining the TCM syndrome type as toxic-heat obstructing lung syndrome;

[0018] when there are coarse breath sounds in the early stage and moist rales in the later stage, determining the TCM syndrome type as wind-cold obstructing lung syndrome;

[0019] determine that the TCM syndrome type is wind-heat obstructing lung syndrome when there are rough respiratory sounds, and dense moist rales and wheezing sounds;

[0020] determine that the TCM syndrome type is yin deficiency and lung heat syndrome when the moist rales are reduced or disappeared, and the respiratory sounds are normal;

[0021] determine that the TCM syndrome type is lung and spleen qi deficiency syndrome when there are no rales or occasional moist rales, and the respiratory sounds are normal.

[0022] In an embodiment, the step of determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared respiratory sound, and the tubular respiratory sound comprises:

[0023] obtaining other TCM data, the other TCM data including inspection data, auscultation data, and palpation data, the auscultation data including sounds heard by a doctor and smells smelled by the doctor;

[0024] determining a syndrome type in the TCM syndrome differentiation type corresponding to the western medical sign according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared respiratory sound, and the tubular respiratory sound, and the other TCM data.

[0025] In an embodiment, the step of determining the TCM medicine recommendation for the child to be diagnosed according to the western medical sign and / or the TCM syndrome type comprises:

[0026] determining that the TCM medicine recommendation includes a traditional Chinese medicine for reducing phlegm when the western medical sign and / or the TCM syndrome type corresponds to moist rales;

[0027] determining that the TCM medicine recommendation includes a traditional Chinese medicine for relieving asthma, opening lung, and reducing phlegm when the western medical sign and / or the TCM syndrome type corresponds to wheezing sound;

[0028] determining that the TCM medicine recommendation includes a traditional Chinese medicine for promoting lung and spleen when the western medical sign and / or the TCM syndrome type corresponds to weakened respiratory sound or tubular respiratory sound;

[0029] determining that the TCM medicine recommendation includes a traditional Chinese medicine for nourishing yin and clearing lung or invigorating spleen and supplementing lung when the western medical sign and / or the TCM syndrome type corresponds to disappeared recovery period auscultation sound.

[0030] In an embodiment, the step of determining the TCM medicine recommendation for the child to be diagnosed according to the western medical sign and / or the TCM syndrome type further comprises:

[0031] reacquiring a new auscultation sound signal of the child to be diagnosed during treatment.

[0032] determine a new western medical sign corresponding to the new auscultation sound signal;

[0033] determine a sign change between the western medical sign before treatment and the new western medical sign, the sign change including a changed sign and a changed degree;

[0034] determine a disease severity and a recovery of the child to be diagnosed according to the sign change, the disease severity and the recovery being used to prompt whether the traditional Chinese medicine recommendation needs to be adjusted.

[0035] In an embodiment, before the step of determining the type of TCM syndrome in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound, the method further comprises:

[0036] obtain type information of the child pneumonia patient, the type information including at least one of age and disease course stage;

[0037] divide the child pneumonia patient into at least one preset group according to the type information, collect an audio reference signal of the heart and lung of the child pneumonia patient in the preset group, and determine a reference representation of the auscultation sound corresponding to the audio reference signal;

[0038] determine a reference type of syndrome in the TCM syndrome differentiation type corresponding to the reference representation of the auscultation sound, and establish an association between the reference representation of the auscultation sound and the reference type of syndrome in the TCM syndrome differentiation type;

[0039] The step of determining the type of TCM syndrome in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound includes:

[0040] determine the type of TCM syndrome in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound of the child to be diagnosed according to the association.

[0041] In addition, to achieve the above-mentioned purpose, the present application also proposes an auscultation device, which comprises a memory, a processor and a computer program stored on the memory and executable on the processor, and the computer program is configured to implement the steps of the association method of the auscultation sound of child pneumonia and TCM diagnosis data as described above.

[0042] In addition, to achieve the above-mentioned purpose, the present application also proposes a storage medium, which is a computer readable storage medium, and the storage medium stores a computer program, and the computer program is executed by a processor to implement the steps of the association method of the auscultation sound of child pneumonia and TCM diagnosis data as described above.

[0043] In addition, to achieve the above object, the application further provides a computer program product, which comprises a computer program, and the computer program realizes the steps of the association method of pediatric pneumonia auscultation sound and TCM diagnosis data when executed by a processor.

[0044] The one or more technical solutions provided in the application have at least the following technical effects:

[0045] The auscultation sound signals of the heart and lung of the pediatric patient to be diagnosed are collected, the western medical signs corresponding to the auscultation sound signals are determined, the western medical signs include the representation of the auscultation sound; the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound is determined; and the TCM medication recommendation for the pediatric patient to be diagnosed is determined according to the western medical signs and / or the TCM syndrome type. The relationship between the western medical signs and the TCM syndrome type provides strong objective evidence and quantitative reference for the TCM syndrome differentiation, especially the excess syndromes such as phlegm-heat obstructing lung and toxic-heat obstructing lung. In the diagnosis and treatment of pediatric pneumonia, TCM highly depends on and integrates the auscultation results, which are used as the key basis for syndrome differentiation, prescription selection (especially the selection of phlegm-heat relieving and asthma relieving drugs), evaluation of curative effect and prognosis. BRIEF DESCRIPTION OF DRAWINGS

[0046] The accompanying drawings, which are incorporated into and form a part of the specification, illustrate an embodiment consistent with the present application and, together with the description, serve to explain the principles of the application.

[0047] In order to more clearly illustrate the technical solutions in the embodiments of the application or the prior art, the accompanying drawings needed to be used in the embodiments or prior art description will be briefly introduced as follows. Obviously, for those skilled in the art, other drawings can also be obtained based on these drawings without creative labor.

[0048] Figure 1 A flowchart is provided for the pediatric pneumonia auscultation sound and TCM diagnosis data association method embodiment one of the application;

[0049] Figure 2 A flowchart is provided for the pediatric pneumonia auscultation sound and TCM diagnosis data association method embodiment two of the application;

[0050] Figure 3 A data fusion flowchart is provided for the pediatric pneumonia auscultation sound and TCM diagnosis data association method embodiment two of the application;

[0051] Figure 4 A flowchart is provided for the pediatric pneumonia auscultation sound and TCM diagnosis data association method embodiment three of the application;

[0052] Figure 5A flowchart provided for the fourth embodiment of the method for associating auscultation sound of pediatric pneumonia and TCM diagnosis data of the application;

[0053] Figure 6 A flowchart provided for the fifth embodiment of the method for associating auscultation sound of pediatric pneumonia and TCM diagnosis data of the application;

[0054] Figure 7 A device structure diagram of the hardware running environment involved in the method for associating auscultation sound of pediatric pneumonia and TCM diagnosis data in the embodiments of the application.

[0055] The object implementation, functional features and advantages of the application will be further described with reference to the embodiments and the accompanying drawings. DETAILED DESCRIPTION

[0056] It should be understood that the specific embodiments described herein are only used to explain the technical solutions of the application, and are not used to limit the application.

[0057] In order to better understand the technical solutions of the application, the specific embodiments will be described in detail below with reference to the drawings and the accompanying drawings.

[0058] The traditional auscultation method has certain limitations in the diagnosis process, and the diagnosis result is highly dependent on the clinical experience of doctors, and multiple diagnosis items need to be checked for auxiliary diagnosis, which finally leads to the delay of diagnosis of pediatric pneumonia.

[0059] The main solution of the embodiments of the application is to collect the heart and lung auscultation sound signals of the pediatric patients to be diagnosed, determine the representation of the auscultation sound in the western medical auxiliary examination corresponding to the auscultation sound signals, and the western medical signs include the representation of the auscultation sound; determine the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound; and determine the TCM medication recommendation for the pediatric patients to be diagnosed according to the western medical signs and / or the TCM syndrome type.

[0060] In this embodiment, for the convenience of description, the following is described with the auscultation device as the execution subject.

[0061] The application provides a solution, which provides strong objective evidence and quantitative reference for TCM syndrome differentiation, especially for excess syndromes such as phlegm-heat obstructing lung and toxic-heat obstructing lung, through the relationship between western medical signs and syndrome types of TCM syndrome differentiation, quickly diagnoses and determines the syndrome type corresponding to the auscultation sound signal and the TCM medication recommendation, and improves the diagnosis speed of pediatric pneumonia and the key basis for evaluating the efficacy and prognosis of TCM pediatric pneumonia treatment through auscultation.

[0062] It should be noted that the execution subject of the embodiment can be a computing service device with data processing, network communication and program running functions, such as a tablet computer, a personal computer, a mobile phone, or an electronic device capable of realizing the above functions, a stethoscope device, etc. The stethoscope device can also be referred to as a pediatric pneumonia auscultation sound and traditional Chinese medicine diagnosis data association device. The following describes the embodiment and each of the following embodiments by taking the stethoscope device as an example.

[0063] Based on this, the application provides a pediatric pneumonia auscultation sound and traditional Chinese medicine diagnosis data association method, which is described with reference to Figure 1 , Figure 1 FIG. 1 is a flowchart of a pediatric pneumonia auscultation sound and traditional Chinese medicine diagnosis data association method according to a first embodiment of the application.

[0064] In the embodiment, the pediatric pneumonia auscultation sound and traditional Chinese medicine diagnosis data association method includes steps S10-S30.

[0065] Step S10, collecting the heart and lung auscultation sound signal of the child to be diagnosed, and determining the auscultation sound representation in the western medicine auxiliary examination corresponding to the auscultation sound signal. The western medicine signs include the auscultation sound representation.

[0066] The auscultation sound signal is a sound signal generated by airflow through the airway and alveoli during the breathing process recorded by the stethoscope device, reflecting the airway patency, lung tissue elasticity and abnormal lesions. Optionally, the stethoscope device can be a traditional stethoscope, an electronic stethoscope, a wearable device, etc.

[0067] In actual application, the electronic stethoscope is close to the heart and lung of the child to be diagnosed. The electronic stethoscope collects the auscultation sound signal of the heart and lung of the child to be diagnosed. The electronic stethoscope directly analyzes the auscultation sound signal, and then quickly diagnoses the child pneumonia, quickly obtains the corresponding traditional Chinese medicine syndrome differentiation type, is beneficial to the traditional Chinese medicine prescription selection, corresponding treatment, and dynamic understanding of the curative effect and prognosis.

[0068] In the application scenario of telemedicine, the parent collects the auscultation sound signal of the heart and lung of the child to be diagnosed by the electronic stethoscope, and uploads the auscultation sound signal of the heart and lung of the child to be diagnosed to the network end. The network end applies the method of the application to make a preliminary diagnosis based on the auscultation sound signal, diagnoses the child pneumonia, avoids wasting the diagnosis time of the parents on the way, and ensures the timeliness of the diagnosis of the child pneumonia. Optionally, after diagnosing the child pneumonia, the online traditional Chinese medicine consultation is connected.

[0069] In the present application, the western medical signs mainly include the representation of auscultation sound, that is, the result of auscultation sound, wherein the auscultation sound includes moist rales, breath sounds, wheezing sound and tubular breath sound, etc. Optionally, the auscultation sound includes moist rales, breath sounds, wheezing sound and tubular breath sound in different stages of disease course, and can also include moist rales, breath sounds, wheezing sound and tubular breath sound in different degrees. For example, the auscultation sound includes fine moist rales, coarse moist rales, large bubbling sound, wheezing sound, weakened or disappeared breath sound, tubular breath sound, bronchial breath sound, etc.

[0070] In the western medical signs, fine moist rales are the most diagnostic. Fine moist rales are obvious at the end of inspiration, with small and dense sounds, like the sound of twisting hair or the sound of water bubble breaking. Fine moist rales indicate inflammatory exudate in alveoli or small bronchi, which is a typical sign of alveolitis. In the field of traditional Chinese medicine, it indicates the presence of phlegm, phlegm turbidity or phlegm heat obstructing the lung.

[0071] In the western medical signs, coarse moist rales or large bubbling sound are obvious in the early inspiration, with relatively large and loud sounds. Coarse moist rales or large bubbling sound indicate a large amount of thin secretions in the trachea, main bronchi or cavity. In the field of traditional Chinese medicine, it is considered as a sign of phlegm turbidity.

[0072] In the western medical signs, wheezing sound is a high-pitched whistling sound in the expiratory phase. Wheezing sound indicates small bronchial spasm and stenosis, which is commonly seen in wheezing pneumonia, syncytial virus infection, some mycoplasma pneumonia and allergic factors. In the field of traditional Chinese medicine, it is closely related to lung qi stagnation and phlegm qi obstruction, and is an important sign of asthma.

[0073] In the western medical signs, weakened or disappeared breath sound indicates that the range of pulmonary consolidation is large, there is pleural effusion, pneumothorax or the bronchus is completely blocked. In the field of traditional Chinese medicine, it is considered as a serious state of lung qi stagnation or lung qi obstruction.

[0074] In the western medical signs, tubular breath sound or bronchial breath sound is similar to the breath sound heard in the trachea and main bronchus, with strong expiratory phase and high pitch. Tubular breath sound or bronchial breath sound indicates pulmonary consolidation, such as lung tissue densification and enhanced transmission, and also indicates lung qi obstruction.

[0075] Step S20, determining the type of TCM syndrome in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound.

[0076] In the present embodiment, the representation of the auscultation sound is associated with the type of syndrome in the TCM syndrome differentiation type. After determining the representation of the auscultation sound, the type of syndrome in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound is determined based on the association.

[0077] In the field of traditional Chinese medicine, TCM syndrome differentiation is to determine the type of syndrome, and the type of syndrome is the specific conclusion after syndrome differentiation, which are interrelated and provide basis for diagnosis and treatment of TCM. The occurrence and development of diseases are the result of physiological dysfunction of viscera, meridians, blood and other physiological functions under the action of pathogenic factors. TCM syndrome differentiation is to comprehensively analyze various symptoms, signs, medical history and other information of patients under the guidance of TCM theory, to identify the viscera and meridians of the disease, to judge the cause, nature and tendency of the disease, and to classify the disease into a certain specific syndrome type. Syndrome type is the embodiment of TCM syndrome differentiation. Syndrome type is a summary of the nature of the current stage of the disease, and a comprehensive summary of the cause, location, nature, and tendency of the disease at a certain stage.

[0078] In clinical practice, pediatricians (whether Western or Chinese medicine background) will pay great attention to the results of auscultation when diagnosing and treating children with pneumonia. TCM practitioners will organically integrate these results into the framework of TCM four diagnostic methods, making the syndrome more accurate and the treatment more targeted. The dynamic changes of auscultation sound are also one of the important objective indicators for evaluating the effect of TCM treatment of pneumonia.

[0079] Step S30, determining the TCM medication recommendation for the child to be diagnosed according to the Western medical signs and / or the TCM syndrome type.

[0080] Using the objectivity and accuracy of Western medical auscultation to enrich and verify the TCM auscultation and syndrome differentiation, and at the same time using the advantages of TCM holistic view and syndrome differentiation and treatment, individualized treatment according to pathogenesis can improve the symptoms of pneumonia and promote the absorption and recovery of lung inflammation.

[0081] Alternatively, the TCM medication recommendation for the child to be diagnosed is determined according to the Western medical signs. Different Western medical signs correspond to different TCM medication recommendations.

[0082] Alternatively, the TCM medication recommendation for the child to be diagnosed is determined according to the syndrome type. Different syndrome types correspond to different TCM medication recommendations. For example, for children with TCM syndrome differentiation of phlegm-heat obstructing lung, the TCM prescription may contain heat-clearing and phlegm-eliminating drugs such as Gualou and Beimu, and targeted medication can better regulate the body function of children and achieve the purpose of treating diseases.

[0083] Alternatively, the TCM medication recommendation for the child to be diagnosed is determined according to the Western medical signs and the syndrome type. The Western medical signs and the syndrome type are combined to determine the TCM medication recommendation.

[0084] In the technical scheme of the embodiment, the heart-lung auscultation sound signals of the child to be diagnosed are collected, the representation of the auscultation sound in the western medical auxiliary examination corresponding to the auscultation sound signals is determined, the western medical sign includes the representation of the auscultation sound, the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound is determined, and the TCM medication recommendation for the child to be diagnosed is determined according to the western medical sign and / or the TCM syndrome type. The relationship between the western medical sign and the TCM syndrome type is used to quickly diagnose and determine the syndrome type corresponding to the auscultation sound signals and the TCM medication recommendation, thereby improving the diagnosis speed of the child pneumonia and the timeliness of the treatment.

[0085] Based on any of the above embodiments of the present application, in the second embodiment of the present application, the same or similar contents as the above embodiments can be referred to the above introduction, and will not be described in detail. On this basis, please refer to Figure 2 , step S10 further includes:

[0086] Step S11, extracting the signal features of the auscultation sound signals, the signal features including at least one of time domain features, frequency domain features, time-frequency features and perception features;

[0087] Step S12, determining the western medical sign according to the signal features, the western medical sign including at least one of the representation of the auscultation sound, such as fine moist rales, coarse moist rales, wheezing sound, weakened or disappeared breath sound, and tubular breath sound.

[0088] In the embodiment, the time domain features include at least one of amplitude envelope, zero-crossing rate, energy, root mean square energy, peak amplitude, autocorrelation function; the frequency domain features include at least one of spectral centroid, spectral bandwidth, spectral spread, spectral flatness, spectral roll-off point, spectral flux, mel-frequency cepstral coefficient, chroma feature, and level contour feature; the time-frequency features include at least one of spectrogram, constant Q transform, and wavelet transform coefficient; and the perception features include at least one of loudness, pitch, and timbre.

[0089] Optionally, the signal features further include high-level features and feature combinations, wherein the high-level features include fundamental frequency and harmonic structure, feature statistics, feature difference, and feature combinations thereof.

[0090] The generation of moist rales is related to the secretion in the trachea, bronchus or bronchiole lumen, and the position of the moist rales can be determined by accurately analyzing the signal features of the auscultation sound, such as the position of the airway of large bubble sound and small bubble sound, and the number and nature of the moist rales, such as continuity or discontinuity. For wheezing sound, it can also be accurately judged whether it occurs in the expiratory phase or the inspiratory phase, and whether it is high-pitched or low-pitched wheezing sound, which is of great significance for diagnosing diseases such as bronchial asthma and asthmatic bronchitis.

[0091] Optionally, based on the acquired auscultation sound signal, an auscultation sound signal data set is obtained; the auscultation sound signal data set is normalized and signal denoising processed to obtain preprocessed auscultation sound signal data; the preprocessed auscultation sound signal data is feature extracted to determine the signal features of the auscultation sound signal data, including the mel frequency, and based on the mel frequency, the cepstrum analysis is performed to obtain the mel cepstrum coefficient of the auscultation sound signal. The mel frequency is a frequency scale related to the auditory characteristics of the human ear. By performing mel frequency analysis on the respiratory sound data, the human auditory system can better simulate the way of perceiving sound. This helps to highlight the frequency components related to diseases in the auscultation sound signal, such as abnormal sounds such as fine crackles, wheezing, etc. The frequency range in which the sound is located provides a more meaningful basis for subsequent feature extraction.

[0092] Optionally, the time domain features in the signal features include the respiratory cycle length and the abnormal sound duration ratio. The frequency domain features in the signal features include the principal component of the mel frequency cepstrum coefficient and the energy concentrated in a specific frequency band, such as 200-600Hz of fine crackles. Optionally, the signal features also include nonlinear features, including sample entropy, which is used to measure the complexity of respiratory sound. Optionally, the auscultation sound analysis includes time-frequency analysis, which uses short-time Fourier transform to locate the fine crackle sound segment, such as 200-600Hz.

[0093] The fine crackles, coarse crackles, wheezing, respiratory sound weakening, disappearance or extension, and tubular breath sounds in the representation of the auscultation sound can be respectively determined based on the description labels of the auscultation sound, such as the A-E sound features in the auscultation sound determined after training and feature analysis, so as to bind the A sound feature as fine crackles; the B sound feature is bound as coarse crackles; the C sound feature is bound as wheezing; the D sound feature is bound as respiratory sound; and the E sound feature is bound as tubular breath sound. Of course, it can also be bound based on other rules, which is not limited herein.

[0094] In an embodiment, a general parameter model for cardiopulmonary sound auscultation (Western medicine) and four diagnostic methods (TCM) is established, such as the program of the data processing model:

[0095] def preprocess_integrated_data(audio_data, tcm_data, patient_info):

[0096] Comply with ISO 23961 (TCM) and ISO 13485 (Western medicine equipment) standards:

[0097] audio_data: heart / lung sound time domain signal (sampling rate ≥ 44kHz)

[0098] tcm_data: four diagnostic data (tongue map / pulse / wave diagnosis / question diagnosis)

[0099] patient_info: Patient basic information (including region, race)

[0100] Output: Standardized feature matrix

[0101] Where the program of Western medicine heart and lung sound processing (ERS / ATS 2023 standard) is:

[0102] heart_clean = adaptive_wiener_filter(

[0103] audio_data['heart'],

[0104] noise_profile=audio_data['env_noise'],

[0105] freq_range=(20, 150)# Heart sound main frequency band )

[0107] lung_features = extract_lung_features(

[0108] audio_data['lung'],

[0109] min_breath_cycle=1.2,# Shortest breath cycle (s)

[0110] crackle_threshold=0.35# Wet rale detection threshold )

[0112] Where the program of Chinese medicine four diagnostic methods (ISO 23961:2023) is:

[0113] # Tongue diagnosis standardization

[0114] tongue_std = normalize_tongue_image(

[0115] tcm_data['tongue_img'],

[0116] color_space='CIELAB',# ISO recommended color space

[0117] roi_method='U-Net_ISO' )

[0119] # Pulse diagnosis processing

[0120] pulse_clean = process_pulse_wave(

[0121] tcm_data['pulse'],

[0122] remove_baseline=True,

[0123] bandpass=(0.5, 40)# Pulse characteristic frequency band )

[0125] The core procedure for multimodal spatiotemporal alignment is as follows:

[0126] aligned_data = dynamic_alignment({

[0127] 'heart': extract_heart_features(heart_clean),

[0128] 'lung': lung_features,

[0129] 'tongue': extract_tongue_features(tongue_std),

[0130] 'pulse': extract_pulse_features(pulse_clean),

[0131] 'symptoms': encode_symptoms(tcm_data['symptoms']) # Encode the consultation text

[0132] }, sync_method='DTW_ECG')

[0133] The procedure for international standard feature conversion is as follows:

[0134] return {

[0135] 'western': apply_iso_transform(aligned_data['cardiopulmonary'], 'ISO_13485'),

[0136] 'tcm': apply_iso_transform(aligned_data['tcm'], 'ISO_23961_2023')

[0137] }

[0138] Exemplary, refer to Figure 3 , Figure 3 The data fusion process provided by the present application is shown in the figure, which gives the spatial mapping of heart sound features and lung sound features to obtain western decision flow, while the results of traditional Chinese medicine four diagnostic features are spatially mapped to obtain traditional Chinese medicine decision flow, so as to internationally recognize the western decision flow and the traditional Chinese medicine decision flow above, and then determine the different weight of traditional Chinese and western medicine based on different regional geographical adaptation factors, and then fuse the parameters based on different diseases such as heart failure and pneumonia, and then output the actual diagnosis disease, so as to complete the diagnosis of the disease. Exemplary, the parameter conversion rule (ISO standard mutual recognition) is shown in Table 1 as follows:

[0139]

[0140] Table 1

[0141] In an embodiment, a program design method of a traditional Chinese and western medicine mutual recognition computing engine is also provided, such as:

[0142] def iso_integration(western_feat, tcm_feat, patient_info):

[0143] """International standard mutual recognition calculation (core)"""

[0144] # 1. Western parameter standardization

[0145] iso_western = {

[0146] 'CR': 20 * math.log10(western_feat['S2_amp'] / western_feat['S1_amp']),

[0147] 'CD': western_feat['crackle_count'] / (western_feat['rec_time'] / 60) *patient_info['BMI'] / 22

[0148] }

[0149] Among them, the program of traditional Chinese medicine parameter standardization is:

[0150] iso_tcm = {

[0151] 'YGI': 0.28*tcm_feat['tongue_L'] + 0.72*tcm_feat['tongue_b'],

[0152] 'WSI': integrate(np.abs(np.diff(tcm_feat['pulse']))),

[0153] 'SYM': tcm_feat['symptom_score']

[0154] }

[0155] where the procedure of dynamic weight generation (innovation) is:

[0156] weights = get_dynamic_weights(

[0157] disease=patient_info['diagnosis'],

[0158] region=patient_info['region'],

[0159] phase=patient_info['disease_phase']# acute / chronic )

[0161] where the procedure of generating international mutual recognition parameters is:

[0162] return {

[0163] 'Global_Heart_Lung_Index':

[0164] weights['western']*iso_western['CR']+

[0165] weights['tcm']*iso_tcm['WSI'],

[0166] 'Syndrome_Risk_Score':

[0167] iso_tcm['YGI'] * (0.5 + 0.05*patient_info['age'] / 30) +0.3*iso_tcm['SYM']

[0168] }

[0169] An exemplary procedure of the validation method (quadruple gold standard) can be:

[0170] def quad_validation(iso_output, patient_info):

[0171] International Quadruple Gold Standard Validation System

[0172] Western Medicine Equipment Validation:

[0173] western_val = {

[0174] 'vs_echo': pearsonr(iso_output['CR'], echo_ef),

[0175] 'vs_CT': accuracy(iso_output['CD'], ct_score)

[0176] }

[0177] Traditional Chinese Medicine Expert Validation:

[0178] tcm_val = {

[0179] 'kappa_global': cohen_kappa(

[0180] iso_output['Syndrome_Risk_Score'],

[0181] [cn_expert, eu_expert]# Multiple Experts )

[0183] }

[0184] International Standard Compliance:

[0185] iso_val = {

[0186] 'traceability_error': check_iso_compliance(iso_output),

[0187] 'terminology_match': match_iso_terms(iso_output)

[0188] }

[0189] Clinical Endpoint Validation (Hard Endpoint):

[0190] clinical_val = {

[0191] 'mortality_auc': roc_auc_score(iso_output['Risk_Score'], mortality_30d),

[0192] 'hosp_days_corr': spearmanr(iso_output['Score'], hospital_days)

[0193] }

[0194] return {**western_val, **tcm_val, **iso_val, **clinical_val}

[0195] Further, the template quantity and template index are as follows formula (1) and table 2:

[0196] (1)

[0197] Wherein, Kregion is regional stratification, such as Asia / Europe / America≥100 cases per layer, Kdisease is disease stratification, such as heart failure / pneumonia / chronic obstructive pulmonary disease≥50 cases per layer, and the minimum sample size≥600 cases.

[0198]

[0199] Table 2

[0200] Exemplary, the pseudo code implementation (international mutual recognition core) is as follows:

[0201] def global_reconciliation(features, patient_info):

[0202] "International standard mutual recognition calculation engine"

[0203] Feature standardization (ISO conversion):

[0204] western_iso = transform_to_iso(features['western'], '13485')

[0205] tcm_iso = transform_to_iso(features['tcm'], '23961')

[0206] Dynamic weight generation (core)

[0207] weight_table = {

[0208] 'HF': {'western': 0.7, 'tcm': 0.3},# Heart failure

[0209] 'PN': {'western': 0.4, 'tcm': 0.6},# Pneumonia

[0210] 'COPD': {'western': 0.5, 'tcm': 0.5}

[0211] }

[0212] weights = adjust_for_region(

[0213] base_weights=weight_table[patient_info['diagnosis']],

[0214] region=patient_info['region'] )

[0216] Generate reconciled parameters

[0217] reconciled_params = {

[0218] 'CardioTCM_Index':

[0219] weights['western'] * western_iso['CR']+

[0220] weights['tcm'] * tcm_iso['WSI'],

[0221] 'Global_Syndrome_Score':

[0222] tcm_iso['YGI'] * symptom_amplifier(patient_info['symptoms'])

[0223] }

[0224] Output in ISO standard format

[0225] return format_as_iso(reconciled_params, version="2025")

[0226] For example, there are the following differences in Table 3 for users in different regions:

[0227]

[0228] Table 3

[0229] In the technical scheme of the embodiment, the characteristics of the auscultation sound signals are extracted, the heart and lung audio is analyzed from multiple dimensions, and the accuracy and comprehensiveness of the western medical sign determination are improved. The western medical signs such as moist rales, breath sounds and wheezing sounds are determined according to the signal characteristics, and the pathological state of the heart and lung can be more accurately judged, so as to facilitate subsequent syndrome differentiation and classification of children to be diagnosed.

[0230] Based on any of the above embodiments of the present application, in the third embodiment of the present application, the same or similar contents as the above embodiments can be referred to the above introduction, and will not be described in detail. On this basis, please refer to Figure 4 , step S20 further comprises:

[0231] Step S21, according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the breath sound weakening or disappearing, and the tubular breath sound, determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound.

[0232] Optionally, when there are dense fine moist rales and coarse moist rales, and accompanied by breath sound changes, wherein the breath sound changes include breath sound enhancement or weakening, the TCM syndrome type is determined as phlegm-heat closing lung syndrome. Optionally, when there are dense fine moist rales in the preset lung range, and there are tubular breath sound and breath sound weakening, the TCM syndrome type is determined as toxic heat closing lung syndrome; optionally, when there are coarse breath sounds in the early stage, and there are moist rales in the later stage, the TCM syndrome type is determined as wind-cold closing lung syndrome; optionally, when there are coarse breath sounds, and dense moist rales and wheezing sounds, the TCM syndrome type is determined as wind-heat closing lung syndrome; optionally, when the moist rales are reduced or disappeared, and the breath sound is normal, the TCM syndrome type is determined as yin deficiency and lung heat syndrome; optionally, when there is no rales or occasional moist rales, and the breath sound is normal or slightly weak, the TCM syndrome type is determined as lung and spleen qi deficiency syndrome.

[0233] The role of auscultation sound in TCM diagnosis and treatment is to assist in syndrome differentiation. Auscultation sound is an important evidence for judging the key elements of phlegm, heat, closing and wheezing. For example, moist rales indicate phlegm, and wheezing sound indicates qi closing and phlegm obstruction.

[0234] In an optional embodiment, other TCM data is obtained, the other TCM data including inspection data, smelling data and palpation data, the smelling data including sounds heard by the doctor and smells smelled by the doctor; according to at least one of the moist rales, the breath sound and the wheezing sound, and the other TCM data, the syndrome type in the TCM syndrome differentiation type corresponding to the western medical sign is determined.

[0235] Traditional Chinese medicine auscultation includes listening to sound and smell. Among them, the sound includes coughing sound, breathing sound, phlegm sound, crying sound, language sound, etc. The ancient Chinese medical books describe that the throat water chicken sound is similar to wheezing sound, the murmur sound is similar to moist rale, and the shortness of breath is directly corresponding to the modern auscultation findings of wheezing sound, moist rale and shortness of breath. In modern pediatric clinical practice of traditional Chinese medicine, lung auscultation has become an indispensable extension and refinement of traditional Chinese medicine auscultation, and is an important embodiment of the objectification of traditional Chinese medicine four diagnoses. Doctors will include the auscultation results in the category of auscultation as an important objective basis for diagnosis.

[0236] Optionally, the auscultation sound includes dense fine moist rales, possibly accompanied by coarse moist rales, and the respiratory sound may be enhanced or weakened, and if accompanied by airway spasm, wheezing sound may be present. Other traditional Chinese medicine data include: high fever, severe cough, yellow and thick sputum or phlegm sound in the throat, shortness of breath, red face, dry mouth, red throat, red tongue with yellow and greasy fur, slippery and rapid pulse, and purple and sluggish fingerprints. At this time, the moist rale directly corresponds to the pathogenesis of phlegm heat accumulation, and the auscultation sound corresponds to the phlegm heat closing lung syndrome.

[0237] Optionally, the auscultation sound includes auscultation signs that are often more obvious and extensive, dense fine moist rales, tubular breathing sound, and weakened respiratory sound, which may be caused by severe inflammation and exudation. When the condition is critical, the auscultation may be atypical. Other traditional Chinese medicine data include high fever that does not subside, severe cough, severe wheezing, restlessness or mental debilitation, cyanotic lips, deep red or purple tongue, yellow and thick fur or little fur without saliva, rapid and fine pulse, and purple and dark fingerprints to the point of death. The extensive moist rales and consolidation signs reflect the severe pathogenesis of heat-toxicity, lung collateral obstruction, and sputum formation from the burning of saliva. At this time, the auscultation sound corresponds to the phlegm heat closing lung syndrome.

[0238] It should be noted that the enhancement or weakening or disappearance of the respiratory sound is in terms of the sound intensity of the normal respiratory sound. The enhancement of the respiratory sound is higher than the sound intensity of the normal respiratory sound, and the weakening or disappearance of the respiratory sound is lower than the sound intensity of the normal respiratory sound.

[0239] Optionally, the auscultation sound includes early possible auscultation without abnormalities or only rough respiratory sound. As the disease progresses, scattered moist rales may appear after sputum is generated. Other traditional Chinese medicine data include cold with high fever, light, no sweating, heavy coughing sound, thin and white sputum that is easy to cough, and later may turn yellow, nasal congestion with clear nasal discharge, dry mouth, no red throat, pale red tongue with thin white fur, tight pulse, and floating red fingerprints. Early auscultation negative or rough sound reflects the cold binding lung, and the lung qi fails to be diffused. The late moist rales suggest that cold evil enters the interior and generates heat and sputum or cold sputum blocks the lung. At this time, the auscultation sound corresponds to the wind-cold closing lung syndrome.

[0240] Optionally, the auscultation sound includes early rough breath sound, faster appearing scattered or more intensive moist rales, and possibly wheezing sound if airway is highly reactive. Other TCM data include heavy fever with aversion to cold, sweating, cough with yellow and sticky sputum, nasal obstruction with yellow discharge, thirst with red and sore throat, red and thin yellowish tongue fur on the edge of the tongue, floating and uneven pulse, and pale and purple finger print. Moist rales reflect the pathogenic wind-heat burning body fluid into phlegm, which blocks the airway. At this time, the auscultation sound corresponds to wind-heat obstructing lung syndrome.

[0241] Optionally, the auscultation sound includes reduced or disappeared moist rales, or only a few scattered moist rales, and possibly normal breath sound. Other TCM data include low fever or irregular fever, dry cough without or with little sputum, dry mouth and throat, hot hands and feet, night sweat, flushed face, red tongue with little fluid and little or peeled tongue fur, thin and rapid pulse, and pale and purple finger print. The auscultation sound indicates that the phlegm is gradually reduced, but the internal heat of yin deficiency is not cleared. At this time, the auscultation sound corresponds to yin deficiency and lung heat syndrome, which is commonly seen in the recovery or protracted stage of pneumonia.

[0242] Optionally, the auscultation sound includes usually no rales or only a few and rare moist rales, and possibly normal or slightly weak breath sound. Other TCM data include weak cough, white and clear sputum, shortness of breath, lazy speech, sweating when moving, loss of appetite, pale complexion, loose and thin stool, pale and swollen tongue with white and slippery fur, thin and weak pulse, and pale finger print. A small amount of thin rales or weak breath sound reflects lung and spleen qi deficiency, and weak transportation and transformation, with remaining phlegm not cleared or phlegm wetness generated internally. At this time, the auscultation sound corresponds to lung and spleen qi deficiency syndrome, which is commonly seen in the recovery or protracted stage of pneumonia.

[0243] In the technical solution of the present embodiment, different syndrome types differ in the manifestations of moist rales, breath sound, and wheezing sound. Western medical signs provide quantifiable indicators and objective basis for TCM differentiation, while TCM differentiation provides holistic concept and syndrome differentiation and treatment ideas for western medical treatment, which helps to break the discipline barriers between TCM and western medicine, and improve the accuracy and speed of pneumonia diagnosis.

[0244] Based on any of the above embodiments of the present application, in the fourth embodiment of the present application, the same or similar contents as the above embodiments can be referred to the above introduction, and will not be described hereinafter. On this basis, please refer to Figure 5 , step S30 further includes:

[0245] Step S31, when the western medical sign and / or the TCM syndrome type corresponds to moist rales, it is determined that the TCM medication recommendation includes phlegm-removing Chinese medicine;

[0246] Step S32, when the western medical sign and / or the TCM syndrome type corresponds to wheezing sound, it is determined that the TCM medication recommendation includes Chinese medicine for relieving asthma and opening lung, and for reducing qi and removing phlegm;

[0247] Step S33, when the Western medicine signs and / or the TCM syndrome types correspond to weakened respiratory sound or tubular respiratory sound, it is determined that the TCM medication recommendation includes TCMs for promoting lung and opening close, clearing heat and detoxifying;

[0248] Step S34, when the Western medicine signs and / or the TCM syndrome types correspond to disappearance of auscultation sound in the recovery period, it is determined that the TCM medication recommendation includes TCMs for nourishing yin and clearing lung or invigorating spleen and supplementing lung.

[0249] In this embodiment, the auscultation sound of pediatric pneumonia is a key sign for Western medicine to diagnose pneumonia, especially fine moist rales and wheezing sound. In the perspective of TCM, these auscultation sounds are an important part of auscultation, which directly reflects the core pathogenesis of phlegm, heat, close and asthma. The auscultation sound provides strong objective evidence and quantitative reference for TCM syndrome differentiation and typing.

[0250] In the diagnosis and treatment of pediatric pneumonia, TCM highly depends on and integrates the results of auscultation, which is one of the key bases for syndrome differentiation, prescription selection, especially the selection of phlegm-eliminating and asthma-relieving drugs, and the evaluation of curative effect and prognosis.

[0251] Optionally, when there is obvious moist rales, i.e. phlegm accumulation, the application of phlegm-eliminating drugs will be strengthened, such as Banxia, Chenpi, Fuling, Gualoupi, Danshanxi and Zhulixie. Optionally, when there is wheezing sound, i.e. qi close and phlegm obstruction, the drugs for relieving asthma and opening lung and descending qi and eliminating phlegm will be focused on, such as Mahuang, Xingren, Tingshiliu, Sushi, Qianhu, Dilong, etc. Optionally, when there are extensive consolidation signs and weakened / tubular respiratory sound, it indicates that lung close is serious, and the drugs for promoting lung and opening close and clearing heat and detoxifying should be used more, such as Maxingshigan Decoction plus clearing heat and detoxifying drugs. Optionally, when the auscultation sound disappears or basically disappears in the recovery period, the treatment focus will be shifted to nourishing yin and clearing lung or invigorating spleen and supplementing lung.

[0252] In an optional embodiment, after step S30, it further includes: during the treatment process, a new auscultation sound signal of the pediatric patient to be diagnosed is reacquired; a new Western medicine sign corresponding to the new auscultation sound signal is determined; a sign change between the Western medicine sign before the treatment and the new Western medicine sign is determined, the sign change including changed signs and degrees of change; the severity of the disease and the recovery of the pediatric patient to be diagnosed are determined according to the sign change, which is used to prompt whether the TCM medication recommendation needs to be adjusted.

[0253] It should be noted that the reduction, narrowing of range, and decrease in density of moist rales and the alleviation or disappearance of wheezing sound during the treatment process are important objective indicators for judging whether the TCM and overall treatment are effective, whether the phlegm-heat is subsided, and whether the lung close is opened.

[0254] During the treatment process, by reacquiring new auscultation signals and determining new Western medicine signs, the subtle changes in the condition of children can be understood in a timely and dynamic manner. This helps doctors to grasp the development trend of the disease in real time and avoid misjudgment or delay in treatment due to hidden changes in the condition. According to the changes in the signs, it is determined whether the TCM medication recommendation needs to be adjusted, so that the treatment is more targeted and timely. This avoids unnecessary or inappropriate use of drugs, improves treatment effectiveness, and reduces the pain and economic burden of patients. The combination of Western medicine sign monitoring and TCM syndrome differentiation and treatment fully utilizes the advantages of both. Through the changes in signs, the adjustment of TCM medication is guided, making the combination of TCM and Western medicine treatment more closely and coordinated, and improving the overall treatment effect.

[0255] In the technical solution in this embodiment, according to different Western medicine signs and TCM syndrome types, the corresponding TCM medication recommendation is accurately matched, and through accurate drug treatment, the symptoms can be effectively relieved, the disease progression can be controlled, the disease course can be shortened, and the children patients can recover faster, reducing the damage of the disease to the body. The medication strategies for different disease stages and different signs are covered, from reducing phlegm, relieving asthma, and promoting lung to restoring the lung and spleen, forming a complete treatment system, which can comprehensively improve the lung function of patients and promote the improvement of the disease.

[0256] Based on any of the above embodiments of the present application, in the fifth embodiment of the present application, the same or similar contents as the above embodiments can be referred to the above introduction, and will not be described in detail. On this basis, please refer to Figure 6 , before step S20, further comprising:

[0257] Step S40, acquiring type information of children with pneumonia, the type information comprising at least one of age and disease course stage;

[0258] Step S50, according to the type information, dividing the children with pneumonia into at least one preset group, and collecting audio reference signals of the heart and lung of the children with pneumonia in the preset group, and determining reference characteristics of the auscultation sound corresponding to the audio reference signals;

[0259] Step S60, determining the reference characteristics of the auscultation sound corresponding to the reference type of the TCM syndrome differentiation type, and establishing the association between the reference characteristics of the auscultation sound and the reference type of the TCM syndrome differentiation type;

[0260] Step S20 comprises:

[0261] Step S22, according to the association, determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the characteristics of the auscultation sound of the child to be diagnosed.

[0262] Optionally, by grouping the medical diagnosis data of pediatric pneumonia patients according to one or more of the type information such as age, pathogen type, and course stage, the pediatric pneumonia patients with different characteristics can be analyzed hierarchically. This helps doctors more accurately grasp the disease characteristics and disease rules of different pediatric pneumonia patient groups, thereby improving the pertinence and accuracy of diagnosis.

[0263] It should be noted that the pathogen type includes bacterial, viral, atypical pathogen, fungal, etc. For example, the bacterial type includes Streptococcus pneumoniae, Staphylococcus aureus, etc., the viral type includes influenza virus, respiratory syncytial virus, human metapneumovirus, etc., the atypical pathogen includes mycoplasma pneumonia, chlamydia pneumonia, etc., and the fungal type includes Aspergillus, Candida, etc. The course stage of pneumonia can be divided into several stages according to the pathophysiological changes, clinical manifestations and treatment response, and the course characteristics of different pathogen types are different.

[0264] In the technical scheme of the embodiment, the pediatric pneumonia patients are grouped according to the type information such as age and course stage, the characteristics and differences of different types of patients are fully considered, and through grouping analysis, a more accurate correlation can be established according to the characteristics of different pediatric pneumonia patients, thereby improving the accuracy of diagnosis.

[0265] It should be noted that the above examples are only for understanding the present application and do not constitute a limitation on the pediatric pneumonia auscultation sound and traditional Chinese medicine diagnosis data association method of the present application. More forms of simple transformation based on this technical concept are within the protection scope of the present application.

[0266] The present application provides an auscultation device, which comprises at least one processor and a memory in communication connection with the at least one processor; wherein the memory stores instructions executable by the at least one processor, and the instructions are executed by the at least one processor to enable the at least one processor to perform the pediatric pneumonia auscultation sound and traditional Chinese medicine diagnosis data association method in the above-mentioned embodiment one.

[0267] In an optional embodiment, the auscultation device comprises an audio acquisition module, a memory, a processor, and an association program of pediatric pneumonia auscultation sound and traditional Chinese medicine diagnosis data stored on the memory and executable on the processor. The association program of pediatric pneumonia auscultation sound and traditional Chinese medicine diagnosis data is executed by the processor to perform the following steps:

[0268] Acquire the heart and lung auscultation sound signal of the pediatric patient to be diagnosed, determine the representation of the auscultation sound in the western medicine auxiliary examination corresponding to the auscultation sound signal, and the western medical sign includes the representation of the auscultation sound;

[0269] Determine the type of TCM syndrome in TCM syndrome differentiation corresponding to the representation of the auscultation sound;

[0270] According to the western medicine signs and / or the TCM syndrome type, a TCM medication recommendation for the child to be diagnosed is determined.

[0271] In an optional embodiment, when the processor invokes the association program of the auscultation sound of child pneumonia and the TCM diagnosis data stored in the memory, the processor further performs the following steps:

[0272] extracting signal features of the auscultation sound signal, the signal features including at least one of time domain features, frequency domain features, time-frequency features and perceptual features; the time domain features including at least one of amplitude envelope, zero-crossing rate, energy, root mean square energy, peak amplitude, autocorrelation function; the frequency domain features including at least one of spectral centroid, spectral bandwidth, spectral spread, spectral flatness, spectral roll-off point, spectral flux, mel-frequency cepstral coefficient, chroma features, level contour features; the time-frequency features including at least one of spectrogram, constant Q transform, wavelet transform coefficient; the perceptual features including at least one of loudness, pitch, timbre;

[0273] determining the western medicine signs according to the signal features, the western medicine signs including at least one of representation of the auscultation sound, fine moist rales, coarse moist rales, wheezing sound, weakened or disappeared breath sound, tubular breath sound.

[0274] In an optional embodiment, when the processor invokes the association program of the auscultation sound of child pneumonia and the TCM diagnosis data stored in the memory, the processor further performs the following steps:

[0275] determining the TCM syndrome type in the TCM syndrome differentiation type corresponding to the representation of the auscultation sound according to at least one of the fine moist rales, the coarse moist rales, the wheezing sound, the weakened or disappeared breath sound, the tubular breath sound.

[0276] In an optional embodiment, when the processor invokes the association program of the auscultation sound of child pneumonia and the TCM diagnosis data stored in the memory, the processor further performs the following steps:

[0277] when there are dense fine moist rales accompanied by coarse moist rales, and accompanied by breath sound changes, determining that the TCM syndrome type is phlegm-heat obstructing lung syndrome.

[0278] when there are dense fine moist rales in a preset lung range, and there are tubular breath sound and weakened breath sound, determining that the TCM syndrome type is toxic-heat obstructing lung syndrome;

[0279] when there are coarse breath sounds in the early stage and wet rales in the later stage, determining that the TCM syndrome type is wind-cold obstructing lung syndrome;

[0280] when there are coarse breath sounds, dense wet rales and wheezing sound, determining that the TCM syndrome type is wind-heat obstructing lung syndrome;

[0281] when the wet rales are reduced or disappeared, and the respiratory sound is normal, determining that the TCM syndrome type is Yin deficiency and lung heat syndrome;

[0282] when there is no rales or occasional wet rales, and the respiratory sound is normal, determining that the TCM syndrome type is lung and spleen Qi deficiency syndrome.

[0283] In an optional embodiment, when the processor invokes the association program of pediatric pneumonia auscultation sound and TCM diagnosis data stored in the memory, the processor further performs the following steps:

[0284] obtaining other TCM data, the other TCM data including inspection data, auscultation data and palpation data, the auscultation data including sounds heard by the doctor and smells smelled by the doctor;

[0285] determining the syndrome type in the TCM syndrome differentiation type corresponding to the western medical signs according to at least one of the fine wet rales, the coarse wet rales, the wheezing sound, the weakened or disappeared respiratory sound, the tubular respiratory sound, and the other TCM data.

[0286] In an optional embodiment, when the processor invokes the association program of pediatric pneumonia auscultation sound and TCM diagnosis data stored in the memory, the processor further performs the following steps:

[0287] when the western medical signs and / or the TCM syndrome type correspond to wet rales, determining that the TCM medication recommendation includes TCMs for reducing phlegm;

[0288] when the western medical signs and / or the TCM syndrome type correspond to wheezing sound, determining that the TCM medication recommendation includes TCMs for relieving asthma, opening the lung and reducing phlegm;

[0289] when the western medical signs and / or the TCM syndrome type correspond to weakened respiratory sound or tubular respiratory sound, determining that the TCM medication recommendation includes TCMs for promoting the lung and clearing heat;

[0290] when the western medical signs and / or the TCM syndrome type correspond to disappeared recovery period auscultation sound, determining that the TCM medication recommendation includes TCMs for nourishing Yin and clearing lung or invigorating the spleen and supplementing the lung.

[0291] In an optional embodiment, when the processor invokes the association program of pediatric pneumonia auscultation sound and TCM diagnosis data stored in the memory, the processor further performs the following steps:

[0292] during the treatment process, reacquiring a new auscultation sound signal of the pediatric patient to be diagnosed;

[0293] determining new western medical signs corresponding to the new auscultation sound signal;

[0294] determine a sign change between the western medicine sign before treatment and the new western medicine sign, the sign change including a changed sign and a changed degree;

[0295] determine a disease severity and a recovery of the child to be diagnosed according to the sign change, the disease severity and the recovery being used to prompt whether the traditional Chinese medicine prescription needs to be adjusted.

[0296] In an optional embodiment, when the processor invokes the association program of the auscultation sound and the traditional Chinese medicine diagnosis data of the child pneumonia stored in the memory, the processor further performs the following steps:

[0297] obtain type information of the child pneumonia patient, the type information including at least one of age and disease course stage;

[0298] divide the child pneumonia patient into at least one preset group according to the type information, collect an audio reference signal of a heart and lung part of the child pneumonia patient in the preset group, and determine a reference representation of the auscultation sound corresponding to the audio reference signal;

[0299] determine a syndrome reference type in the traditional Chinese medicine syndrome differentiation type corresponding to the reference representation of the auscultation sound, and establish an association relationship between the reference representation of the auscultation sound and the syndrome reference type in the traditional Chinese medicine syndrome differentiation type;

[0300] determine a traditional Chinese medicine syndrome type in the traditional Chinese medicine syndrome differentiation type corresponding to the representation of the auscultation sound of the child to be diagnosed according to the association relationship.

[0301] Reference is made below to Figure 7 which shows a structural schematic diagram of an auscultation device suitable for being used to implement embodiments of the present application. The auscultation device in the embodiments of the present application can include, but is not limited to, a terminal such as a wearable device, an electronic stethoscope, an audio acquisition device, and the like. Figure 7 The auscultation device shown is merely an example and should not bring any limitation to the functions and use range of the embodiments of the present application.

[0302] As Figure 7As shown, the auscultation device can include a processing device 1001 (e.g., a central processing unit, a graphics processing unit, etc.) that can perform various appropriate actions and processes according to programs stored in a read-only memory (ROM) 1002 or loaded from a storage device 1003 into a random access memory (RAM) 1004. Various programs and data required for operation of the auscultation device are also stored in the RAM 1004. The processing device 1001, the ROM 1002, and the RAM 1004 are connected to each other through a bus 1005. An input / output (I / O) interface 1006 is also connected to the bus. Generally, the following systems can be connected to the I / O interface 1006: an input device 1007 including, for example, a touch screen, a touch pad, etc.; an output device 1008 including, for example, a liquid crystal display (LCD), a speaker, a vibrator, etc.; the storage device 1003; and a communication device 1009. The communication device 1009 can allow the auscultation device to communicate wirelessly or by wire with other devices to exchange data. Although the auscultation device with various systems is shown in the figure, it should be understood that all of the systems shown are not required to be implemented or possessed. More or less systems can be alternatively implemented or possessed.

[0303] In particular, according to the embodiments disclosed in the present application, the processes described above with reference to the flowcharts can be implemented as a computer software program. For example, the embodiments disclosed in the present application include a computer program product comprising a computer program carried on a computer readable medium, the computer program containing program codes for executing the methods shown in the flowcharts. In such embodiments, the computer program can be downloaded and installed from a network through the communication device, or installed from the storage device 1003, or installed from the ROM 1002. When the computer program is executed by the processing device 1001, the above-mentioned functions defined in the methods of the embodiments disclosed in the present application are performed.

[0304] The auscultation device provided in the present application adopts the association method of pediatric pneumonia auscultation sound and TCM diagnosis data in the above-mentioned embodiments, which can solve the technical problem of low pediatric pneumonia diagnosis speed. Compared with the prior art, the auscultation device provided in the present application has the same beneficial effects as the association method of pediatric pneumonia auscultation sound and TCM diagnosis data provided in the above-mentioned embodiments, and other technical features in the auscultation device are the same as the features disclosed in the previous embodiment method, which will not be repeated here.

[0305] It should be understood that parts of the present application can be realized by hardware, software, firmware or a combination thereof. In the description of the above embodiments, specific features, structures, materials or characteristics can be combined in any one or more embodiments or examples in a suitable manner.

[0306] The above merely provides the specific implementation of the present application, but the protection scope of the present application is not limited to this. Any person skilled in the art can easily think of the changes or replacements within the technical range disclosed by the present application, which should be covered within the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

[0307] The present application provides a computer readable storage medium having computer readable program instructions (i.e. computer programs) stored thereon, the computer readable program instructions being used to execute the method for associating the auscultation sound of children's pneumonia and the TCM diagnosis data in the above embodiment.

[0308] The computer readable storage medium provided by the present application may, for example, be a U disk, but is not limited to an electric, magnetic, optical, electromagnetic, infrared, or semiconductor system or device, or any combination of the above. More specific examples of the computer readable storage medium can include, but are not limited to, an electric connection with one or more conductive wires, a portable computer disk, a hard disk, a random access memory (RAM), a read only memory (ROM), an erasable programmable read only memory (EPROM or flash memory), an optical fiber, a portable compact disk read only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the above. In the present embodiment, the computer readable storage medium can be any tangible medium containing or storing a program, which can be used by or in combination with an instruction execution system, system or device. The program code contained on the computer readable storage medium can be transmitted by any suitable medium, including but not limited to an electric wire, an optical cable, a radio frequency (RF), etc., or any suitable combination of the above.

[0309] The above computer readable storage medium can be contained in an auscultation device; or can exist separately without being assembled into an auscultation device.

[0310] The computer readable storage medium carries one or more programs, when the one or more programs are executed by the auscultation device, the auscultation device is caused to: provide strong objective evidence and quantitative reference for TCM syndrome differentiation (especially phlegm-heat obstructing lung, toxic-heat obstructing lung and other excess syndromes) by the relationship between western medicine signs and TCM syndrome types. When diagnosing and treating children's pneumonia, TCM highly depends on and integrates the auscultation results, which is used as a key basis for syndrome differentiation, prescription selection (especially the selection of phlegm-heat and asthma drugs), evaluation of curative effect and prognosis. At the same time, through the relationship between western medicine signs and TCM syndrome types, the corresponding syndrome type and TCM drug recommendation of the auscultation sound signal are quickly diagnosed and determined, which improves the diagnosis speed of children's pneumonia and the timeliness of treatment.

[0311] Computer program code for carrying out operations of the present application can be written in any combination of one or more programming languages, including an object oriented programming language such as Java, Smalltalk, C++ or the like and conventional procedural programming languages, such as the "C" programming language or similar programming languages. The program code can execute entirely on the user's computer, partly on the user's computer, as a stand-alone software package, partly on the user's computer and partly on a remote computer or entirely on the remote computer or server. In the latter scenario, the remote computer can be connected to the user's computer through any type of network, including a local area network (LAN) or a wide area network (WAN), or the connection can be made to an external computer (for example, through the Internet using an Internet Service Provider).

[0312] The flowcharts and block diagrams in the drawings illustrate the architecture, functionality, and operation of possible implementations of systems, methods and computer program products according to various embodiments of the present application. In this regard, each block in the flowcharts or block diagrams can represent a module, segment, or portion of code, which comprises one or more executable instructions for implementing the specified logical functions. It should also be noted that in some alternative implementations, the functions noted in the blocks can occur out of the order noted in the figures. For example, two blocks shown in succession may, in fact, be executed substantially concurrently or the blocks can sometimes be executed in the reverse order, depending upon the functionality involved. It will also be noted that each block of the block diagrams and / or flowchart illustrations, and combinations thereof, can be implemented by a dedicated hardware-based system that performs the specified functions or operations, or combinations of hardware and software. The hardware includes, but is not limited to, field-programmable gate arrays (FPGAs) or application-specific integrated circuits (ASICs).

[0313] The modules involved in the embodiments of the present application can be implemented in the form of software or in the form of hardware. In some cases, the name of the module does not constitute a limitation on the unit itself.

[0314] The readable storage medium provided by the present application is a computer readable storage medium, which stores computer readable program instructions (i.e. computer program) for executing the above-mentioned method for associating pediatric pneumonia auscultation sound and TCM diagnosis data, and can solve the technical problem of low pediatric pneumonia diagnosis speed. Compared with the prior art, the computer readable storage medium provided by the present application has the same beneficial effects as the method for associating pediatric pneumonia auscultation sound and TCM diagnosis data provided by the above-mentioned embodiments, and will not be repeated here.

[0315] The present application also provides a computer program product comprising a computer program, which, when executed by a processor, implements the steps of the method for associating pediatric pneumonia auscultation sound and TCM diagnosis data as described above.

[0316] The computer program product provided by the present application can solve the technical problem of low pediatric pneumonia diagnosis speed. Compared with the prior art, the computer program product provided by the present application has the same beneficial effects as the method for associating pediatric pneumonia auscultation sound and TCM diagnosis data provided by the above-mentioned embodiments, and will not be repeated here.

[0317] The above merely describes some embodiments of the present application, and does not limit the patent scope of the present application. Any equivalent structural transformation, direct / indirect application in other related technical fields, or the like, which is made based on the technical concept of the present application and the content of the specification and drawings, is included in the patent protection scope of the present application.

Claims

1. A method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data, characterized in that, The method includes: Collect auscultation sounds of the heart and lungs of the child to be diagnosed, and extract the signal features of the auscultation sounds; Based on the signal characteristics, Western medicine signs in auxiliary diagnosis are determined, and the Western medicine signs include at least one of the following characteristics of auscultation sounds: fine moist rales, coarse moist rales, wheezing, decreased or absent breath sounds, and tubular breath sounds. To determine the TCM syndrome type in the TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds; Based on the aforementioned Western medicine signs and / or the aforementioned TCM syndrome types, a TCM medication recommendation for the child to be diagnosed is determined. The step of determining the TCM syndrome type in the TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds includes: determining the TCM syndrome type in the TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds based on at least one of the fine moist rales, the coarse moist rales, the wheezing, the decreased or absent breath sounds, and the tubular breath sounds, specifically as follows: When dense fine moist rales are present, accompanied by coarse moist rales, and changes in breath sounds are present, the TCM syndrome type is determined to be phlegm-heat obstructing the lungs syndrome. When there are dense fine moist rales within a preset lung area, and tubular breath sounds and decreased breath sounds are present, the TCM syndrome type is determined to be toxic heat obstructing the lungs syndrome. When coarse breath sounds are present in the early stage and moist rales are present in the later stage, the TCM syndrome type is determined to be wind-cold obstructing the lungs syndrome. When coarse breathing sounds, dense moist rales and wheezing are present, the TCM syndrome type is determined to be wind-heat obstructing the lungs syndrome. When the moist rales decrease or disappear, and the breath sounds are normal, the TCM syndrome type is determined to be Yin deficiency and lung heat syndrome. When there are no rales or only occasional moist rales, and the breath sounds are normal, the TCM syndrome type is determined to be lung and spleen qi deficiency syndrome.

2. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 1, characterized in that, The signal features include at least one of time-domain features, frequency-domain features, time-frequency features, and perceptual features; the time-domain features include at least one of amplitude envelope, zero-crossing rate, energy, peak amplitude, and autocorrelation function; the frequency-domain features include at least one of spectral centroid, spectral bandwidth, spectral spread, spectral flatness, spectral roll-off point, spectral flux, Mel frequency cepstral coefficients, chromaticity features, and pitch profile features; the time-frequency features include at least one of spectrogram, constant Q transform, and wavelet transform coefficients; and the perceptual features include at least one of loudness, pitch, and timbre.

3. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 1, characterized in that, The step of determining the TCM syndrome type in the TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds further includes: Acquire other TCM data, including observation data, auscultation data, and palpation data, wherein the auscultation data includes the sounds heard and the smells detected by the doctor; Based on at least one of the fine moist rales, the coarse moist rales, the wheezing, the decreased or absent breath sounds, the tubular breath sounds, and other TCM data, the syndrome type in the TCM syndrome differentiation corresponding to the Western medicine signs is determined.

4. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 1, characterized in that, The step of determining the recommended TCM medication for the child to be diagnosed based on the Western medicine signs and / or the TCM syndrome type includes: When the Western medicine signs and / or the TCM syndrome types correspond to moist rales, it is determined that the TCM medication recommendation includes expectorant Chinese medicine. When the Western medicine signs and / or the TCM syndrome types correspond to wheezing, the recommended TCM medications include those that relieve asthma, open the lungs, and resolve phlegm. When the Western medicine signs and / or the TCM syndrome types correspond to decreased breath sounds or tubular breath sounds, the recommended TCM medications include those that promote lung function, clear heat and detoxify. When the Western medicine signs and / or the TCM syndrome types correspond to the disappearance of auscultatory sounds during the recovery period, it is determined that the recommended TCM medications include those that nourish Yin and clear the lungs or strengthen the spleen and replenish the lungs.

5. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 4, characterized in that, After the step of determining the recommended TCM medication for the child to be diagnosed based on the Western medicine signs and / or the TCM syndrome type, the method further includes: During the treatment process, new auscultation signals are reacquired from the child to be diagnosed; Identify new Western medical signs corresponding to the new auscultation sound signals; Determine the changes in physical signs between the pre-treatment Western medical signs and the new Western medical signs, including the changed signs and the degree of change; The severity and recovery status of the child's condition are determined based on the changes in the physical signs. The severity and recovery status are used to indicate whether the recommended traditional Chinese medicine medication needs to be adjusted.

6. The method for correlating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in claim 1, characterized in that, Before the step of determining the TCM syndrome type in TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds, the method further includes: Obtain the type information of pediatric pneumonia patients, wherein the type information includes at least one of age and disease stage; Based on the type information, the pediatric pneumonia patients are divided into at least one preset group, and audio reference signals of the cardiopulmonary system of the pediatric pneumonia patients in the preset group are collected to determine the reference representation of the auscultation sound corresponding to the audio reference signal. Determine the syndrome reference type in the TCM syndrome differentiation corresponding to the reference representation of the auscultatory sounds, and establish the correlation between the reference representation of the auscultatory sounds and the syndrome reference type in the TCM syndrome differentiation. The steps for determining the TCM syndrome type in TCM syndrome differentiation corresponding to the characteristics of the auscultatory sounds include: Based on the aforementioned correlation, the TCM syndrome type corresponding to the auscultatory sounds of the child to be diagnosed is determined in the TCM syndrome differentiation.

7. A stethoscope device, characterized in that, The auscultation device includes: a memory, a processor, and a computer program stored in the memory and executable on the processor, the computer program being configured to implement the steps of the method for associating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in any one of claims 1 to 6.

8. A storage medium, characterized in that, The storage medium is a computer-readable storage medium, and a computer program is stored on the storage medium. When the computer program is executed by a processor, it implements the steps of the method for associating auscultation sounds of pediatric pneumonia with traditional Chinese medicine diagnostic data as described in any one of claims 1 to 6.

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