A perm damaged repair composition

Abstract

This invention discloses a hair repair composition for permed hair, comprising, by weight: 0.02-1.0 parts hydrolyzed plant protein, 0.1-2.0 parts biomimetic amino acid complex, 50-95 parts carrier, and 0.5-15 parts additives. The hydrolyzed plant protein is obtained from Moringa seed protein through multi-enzyme synergistic hydrolysis, with a molecular weight less than 3500 Daltons. The biomimetic amino acid complex includes at least wheat amino acids, soybean amino acids, arginine hydrochloride, serine, and threonine. Under weakly acidic conditions, this composition can simultaneously repair broken disulfide bonds, hydrogen bonds, and ionic bonds in hair. The hydrolyzed plant protein provides disulfide bond reconnection sites, and the biomimetic amino acid complex constructs a multi-point weak bond network through hydroxyl and ionic groups, achieving "triple bond repair" synergistically. This invention can significantly improve the mechanical strength, elasticity, and breakage resistance of damaged hair, with long-lasting, gentle, and safe repair effects, suitable for daily care of damaged hair after perming and dyeing.

Description

Technical Field

[0001] This invention relates to the technical field of daily chemical hair care, and in particular to a composition for repairing hair damage caused by perming. Background Technology

[0002] During the perming and dyeing process, hair undergoes multiple chemical and physical processes such as oxidation, reduction, and heating, which cause the hair cuticle to lift, the cortex structure to be damaged, and the supporting chemical bonds such as disulfide bonds, hydrogen bonds, and ionic bonds inside the hair to be broken or weakened, resulting in problems such as decreased strength, reduced elasticity, roughness, tangling, and reduced shine.

[0003] To improve this type of damage, various hair repair products have emerged on the market, often coating the hair surface with proteins, amino acids, or oils to improve its feel. However, existing formulas generally suffer from drawbacks such as active ingredients failing to effectively penetrate the cortex, weak bond networks failing to recover quickly, and repair effects not lasting long. Some products require high temperatures or alkaline conditions to achieve optimal results, which can easily cause further damage to already damaged hair. Especially in home care settings, where the environment and conditions are limited, the gentleness, penetration, and multi-layered repair capabilities of the formula become even more crucial.

[0004] Therefore, there is an urgent need for a perm damage repair composition that can achieve both deep structural repair and surface protection under gentle conditions, and has a stable and long-lasting repair effect, in order to meet the needs of daily hair care. Summary of the Invention

[0005] In view of the shortcomings of the existing technology, the purpose of this invention is to provide a hair repair composition for permed hair.

[0006] A hair damage repair composition comprising the following components in parts by weight:

[0007] Hydrolyzed vegetable protein: 0.02–1.0 parts;

[0008] Biomimetic amino acid complex: 0.1–2.0 parts;

[0009] The biomimetic amino acid complex includes at least wheat amino acids, soybean amino acids, arginine hydrochloride, serine, and threonine.

[0010] Carrier: 50–95 copies;

[0011] Additives: 0.5–15 parts;

[0012] The hydrolyzed plant protein is obtained by enzymatic hydrolysis of Moringa seed protein.

[0013] Hydrolyzed plant proteins are directionally involved in the reconstruction of disulfide bonds (—S—S—), while biomimetic amino acid complexes provide rapid replacement of hydrogen / ionic bonds and network reorganization; both achieve "simultaneous repair of three bonds" in the same formulation system. Specifically:

[0014] After being heated and dyed, cysteine ​​residues undergo multi-stage oxidation (to cysteine ​​sulfonic acid). The active sites in the hydrolyzed plant protein create a reducing / nucleophilic environment within the hair shaft and activate the electrophilicity of the sulfonic acid sites, promoting the substitution of adjacent thiol groups, thereby reconnecting the broken -S-S- and restoring the mechanical framework supported by the α-helix.

[0015] Secondly, the hydroxyl groups of serine / threonine, the cation sites of arginine / lysine, and the carboxyl groups of glutamic acid / aspartic acid in the complex form a large number of reversible hydrogen bonds and salt bonds. These weak bonds are numerous and can quickly rebuild a "multi-point-multi-site" viscoelastic network, reducing stress concentration and improving elasticity and combing smoothness.

[0016] First, hydrogen bonds / ionic bonds act as a scaffold to stabilize the microenvironment, reducing local tearing during shearing and stretching, and providing a relatively stable chemical environment for disulfide bond reconnection. After the -S-S- reconnection, macroscopic strength and fracture toughness are restored. This pathway can occur in a household setting at room temperature in a weakly acidic system, avoiding secondary damage to keratin caused by high temperature / strong alkaline conditions.

[0017] Furthermore, the hydrolyzed plant protein is obtained by sequentially hydrolyzing moringa seed protein with papain, trypsin, and neutral protease.

[0018] Multi-enzyme synergistic hydrolysis gradually loosens the structure of large protein molecules, releasing sites that can be recognized by subsequent enzymes. After specific cleavage by trypsin near basic amino acid residues, more small peptides containing active groups are obtained. Finally, supplementary hydrolysis by neutral protease avoids over-degradation, resulting in a product molecular weight of less than 3500 Daltons. This method is more precise than traditional single-enzyme hydrolysis, and the obtained peptides have the ability to penetrate into the cortex and form a stable film-forming structure on the hair surface, avoiding the deficiency of existing technologies that make it difficult to balance permeability and film-forming properties.

[0019] Furthermore, in the biomimetic amino acid complex, the total weight of serine and threonine accounts for 15% to 35% of the total weight of the biomimetic amino acid complex.

[0020] This ratio provides a suitable number of hydroxyl side chains, forming a uniformly distributed network of weak interactions in the system, thereby enhancing the binding stability with keratin and maintaining a balance between solubility and rheological properties. A ratio below 15% results in insufficient binding sites and a sparse network of weak bonds; a ratio above 35% leads to excessive hydrophilicity, potentially causing precipitation or excessive viscosity. Controlling the ratio within this range yields a more stable and reproducible network of weak bonds, resulting in a durable and uniform repair effect.

[0021] Furthermore, in the biomimetic amino acid complex, the weight ratio of wheat amino acids to soybean amino acids is 1:0.8 to 1.2.

[0022] Wheat amino acids are rich in acidic residues, while soybean amino acids contain more basic residues. This ratio makes the acid-base side chain ratio close to the natural distribution of human hair keratin, making it easier to form stable ion pairings in a weakly acidic environment. This improves the uniformity of amino acid distribution in hair strands, resulting in a denser weak bond network. At the same time, this ratio can also avoid competitive adsorption or precipitation problems caused by component imbalance in the system, making the stability of the complex in the formulation and its affinity with hair strands superior to conventional ratios.

[0023] Furthermore, the weight ratio of the hydrolyzed plant protein to the biomimetic amino acid complex is 0.2:1 to 10:1.

[0024] Within this range, proteins and amino acids maintain the physical stability of the formulation while achieving a uniform compounding effect. Below this range, insufficient protein will lead to difficulty in forming a stable composite film; above this range, excessive protein will increase the viscosity of the system, reducing permeability and ease of use. Within the specified ratio range, the two can work together to maintain system homogeneity and storage stability while ensuring that the reconstruction process of different types of structural bonds is not disturbed.

[0025] Furthermore, the average molecular weight of the hydrolyzed plant protein is less than 3,500 Daltons.

[0026] Within the range where the average molecular weight of hydrolyzed plant protein is less than 3500 Daltons, peptides can both cross the interscalar channels / damage pores to enter the cortex and participate in the —S—S—reconnection, and form a tough composite film with biomimetic amino acids / cationic polysaccharides on the surface. Macroscopically, this results in a simultaneous increase in breaking strength and pre-yield elasticity, as well as enhanced fatigue resistance of hair.

[0027] Furthermore, in the biomimetic amino acid complex, the weight ratio of wheat amino acids to soybean amino acids is 1:1.

[0028] Within this ratio, the ratio of acid / base side chains to hydroxyl side chains in the complex closely approximates the amino acid distribution of human hair keratin, thereby enhancing the sequence / site affinity with keratin and the pairing efficiency near the isoelectric point. At the same addition amount, a denser hydrogen / salt bond network can be formed. Furthermore, it can improve the self-repairability of the "weak bond network" (it can rebuild more quickly after repeated stress), thereby reducing cumulative damage and delaying elasticity loss. At the same time, it can improve the synergistic adsorption / combination stability with hydrolyzed plant proteins and reduce competitive adsorption and precipitation within the formulation.

[0029] Furthermore, the pH value of the composition is 4.5 to 6.5.

[0030] Hair is close to its isoelectric point in the weakly acidic region, where the salt bond (ionic bond) strength is the greatest and the cuticle closure is better. At this pH, the cationic / anionic side groups of biomimetic amino acids are more likely to form stable ion pairs and enhance the weak bond network through the synergistic effect of "ion pair-hydrogen bond".

[0031] Secondly, for disulfide bond reconnection, the weak acid environment avoids excessive expansion and secondary hydrolysis, making the reconnected -S-S- more heat-resistant and oxidation-resistant.

[0032] In addition, this range is skin / scalp-friendly and compatible with daily chemical systems, making it suitable for home use.

[0033] Furthermore, its preparation method includes the following steps:

[0034] S1. Dissolve hydrolyzed plant protein in a portion of the carrier and stir at 200-400 rpm for 10-30 minutes at 25℃-35℃;

[0035] S2. Dissolve the biomimetic amino acid complex in the remaining carrier and adjust the pH to 4.5–6.5;

[0036] S3. Mix the solutions obtained in step S1 and step S2, add the additive, and stir at 200-500 rpm for 20-40 minutes at 25℃-35℃.

[0037] S4. Cool to room temperature to obtain the finished product of the hair damage repair composition.

[0038] Furthermore, the stirring in steps S1 and S3 is carried out using magnetic stirring, and the cooling process is completed by standing for 30 to 60 minutes at an ambient temperature of 20°C to 25°C.

[0039] Compared with the prior art, the beneficial effects of the present invention are mainly reflected in the following aspects:

[0040] (1) The hydrolysate obtained by sequential enzymatic hydrolysis of Moringa seed protein has an average molecular weight of less than 3500 Daltons, which takes into account both permeability and film-forming properties, avoiding the problems of insufficient permeability or unstable film formation of traditional single protein hydrolysates.

[0041] (2) By optimizing the proportion of the biomimetic amino acid complex, the amino acid distribution of human hair keratin is made closer, which improves the affinity and compatibility stability with hair fibers. Existing technologies mostly use single amino acids or animal-derived keratin, which have insufficient affinity.

[0042] (3) In terms of formulation, a scientific ratio range of hydrolyzed plant protein and biomimetic amino acid complex is introduced to ensure the stability and reconstruction efficiency of the system, which is different from the existing technology that relies on a single component or lacks clear ratio control.

[0043] (4) The overall formula can function stably under normal temperature and weak acid conditions, avoiding secondary damage caused by harsh conditions such as high temperature and high alkali. Detailed Implementation

[0044] The present invention will now be described in detail with reference to the embodiments.

[0045] Example 1

[0046] This embodiment discloses a hair perming damage repair composition, comprising the following components in parts by weight:

[0047] Hydrolyzed plant protein: 0.5 parts (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0048] Bionic amino acid complex: 1.0 part (wheat amino acids 30wt%, soybean amino acids 30wt%, arginine hydrochloride 13.4wt%, serine 13.3wt%, threonine 13.3wt%, cosmetic grade, wheat to soybean amino acid ratio is 1:1, serine + threonine total 26.6%).

[0049] Carrier: 70.0 parts deionized water (conductivity ≤5μS / cm), 10.0 parts glycerol, 5.0 parts 1,3-propanediol;

[0050] Additives: 0.8 parts polyglycerol-10 laurate, 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0051] The preparation method is as follows:

[0052] S1. Mix 35.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol, and stir magnetically at 250 rpm for 12 min at 28°C. Slowly add the hydrolyzed vegetable protein solution and stir until transparent.

[0053] S2. Add polyglycerol-10 laurate to the remaining carrier, stir at 280 rpm for 5 min, add the biomimetic amino acid complex in three portions, adjust the pH to 5.2, and continue stirring for 8 min;

[0054] S3. Slowly pour the solution obtained in S1 into the solution in S2 along the wall of the vessel, stir at 230 rpm for 20 min, cool to 30℃ and add preservative, add flavoring at 28℃;

[0055] S4. Allow to stand and cool at 20-25℃ for 40 minutes, filter, and test for appearance, pH (5.2), viscosity and microorganisms. Fill after passing the test.

[0056] Example 2

[0057] This embodiment discloses a hair perming damage repair composition, comprising the following components in parts by weight:

[0058] Hydrolyzed plant protein: 0.2 parts (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0059] Bionic amino acid complex: 1.0 part (wheat amino acids 30wt%, soybean amino acids 30wt%, arginine hydrochloride 13.4wt%, serine 13.3wt%, threonine 13.3wt%, cosmetic grade, wheat to soybean amino acid ratio is 1:1, serine + threonine total 26.6%).

[0060] Carrier: 72.0 parts deionized water (conductivity ≤5μS / cm), 10.0 parts glycerol, 5.0 parts 1,3-propanediol;

[0061] Additives: 0.8 parts polyglycerol-10 laurate, 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0062] The preparation method is as follows:

[0063] S1. Mix 36.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol, and stir magnetically at 250 rpm for 15 min at 28°C. Slowly add the hydrolyzed vegetable protein solution and continue stirring for 10 min until clear and transparent.

[0064] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, stir at 280 rpm for 5 min until completely dispersed, add the biomimetic amino acid complex in three portions, continue stirring for 8 min, add 10% lactic acid solution dropwise to adjust the pH to 4.8, and stir for 5 min;

[0065] S3. Slowly add the solution obtained in S1 to the solution in S2 along the container wall, maintain the stirring speed at 230 rpm, stir for 25 min, add the preservative when the temperature drops to 30℃, add the fragrance when the temperature is 28℃, and stir evenly for 6 min.

[0066] S4. Place in an environment of 20-25℃ and let stand and cool for 40 minutes. Filter through a 100-mesh stainless steel sieve and test the appearance, pH value (4.8), viscosity and microbial indicators. Fill after passing the test.

[0067] Example 3

[0068] This embodiment discloses a hair perming damage repair composition, comprising the following components in parts by weight:

[0069] Hydrolyzed plant protein: 1.0 part (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0070] Biomimetic amino acid complex: 0.1 parts (wheat amino acids 30wt%, soybean amino acids 30wt%, arginine hydrochloride 13.4wt%, serine 13.3wt%, threonine 13.3wt%, cosmetic grade, wheat to soybean amino acid ratio is 1:1, serine + threonine total 26.6%).

[0071] Carrier: 72.0 parts deionized water (conductivity ≤5μS / cm), 10.0 parts glycerol, 5.0 parts 1,3-propanediol;

[0072] Additives: 0.8 parts polyglycerol-10 laurate, 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0073] The preparation method is as follows:

[0074] S1. Mix 36.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol, and stir magnetically at 260 rpm for 20 min at 30°C. Slowly add the hydrolyzed vegetable protein solution and continue stirring for 10 min until homogeneous and transparent.

[0075] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, stir at 280 rpm for 5 min; add the biomimetic amino acid complex, stir at 280 rpm for 8 min, add 10% lactic acid solution dropwise to adjust the pH to 6.2, and stir for 5 min;

[0076] S3. Slowly add solution S1 to solution S2, maintain stirring at 230 rpm for 30 min, add preservative when the temperature drops to 30℃, and add flavoring at 28℃;

[0077] S4. Place in an environment of 20-25℃ and let stand and cool for 45 minutes, filter, and test the appearance, pH value (6.2), viscosity and microbial indicators. After passing the test, fill the container.

[0078] S4. Cool to 25℃, filter, and fill after passing inspection.

[0079] Example 4

[0080] This embodiment discloses a hair perming damage repair composition, comprising the following components in parts by weight:

[0081] Hydrolyzed plant protein: 0.5 parts (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0082] Bionic amino acid complex: 1.0 part (wheat amino acids 30wt%, soybean amino acids 30wt%, arginine hydrochloride 13.4wt%, serine 13.3wt%, threonine 13.3wt%, cosmetic grade, wheat to soybean amino acid ratio is 1:1, serine + threonine total 26.6%).

[0083] Carrier: 70.0 parts deionized water (conductivity ≤5μS / cm), 10.0 parts glycerin (cosmetic grade, ≥99.5%), 5.0 parts 1,3-propanediol (cosmetic grade, ≥99.0%);

[0084] Additives: 0.8 parts polyglycerol-10 laurate (emulsifier), 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0085] The preparation method is as follows:

[0086] S1. Add 35.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol to a clean mixing tank, and magnetically stir at 250 rpm for 15 min at 28°C. Slowly add the hydrolyzed vegetable protein solution and continue stirring for 10 min until clear and transparent.

[0087] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, and stir at 280 rpm for 5 min until completely dispersed; add the biomimetic amino acid complex in three portions, and continue stirring for 8 min; add 10% lactic acid solution dropwise to adjust the pH to 5.0, and stir for 5 min;

[0088] S3. Slowly add the S1 solution along the container wall to the S2 solution, and stir at 230 rpm for 25 min; when the temperature drops to 30℃, add the preservative, and when the temperature reaches 28℃, add the flavoring, and stir evenly for 6 min;

[0089] S4. Place in an environment of 20-25℃ and let stand and cool for 40 minutes. Filter through a 100-mesh stainless steel sieve and test the appearance, pH value (5.0), viscosity and microbial indicators. Fill after passing the test.

[0090] Example 5

[0091] This embodiment discloses a hair perming damage repair composition, comprising the following components in parts by weight:

[0092] Hydrolyzed plant protein: 0.5 parts (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0093] Bionic amino acid complex: 1.0 part (wheat amino acids 30wt%, soybean amino acids 30wt%, arginine hydrochloride 13.4wt%, serine 13.3wt%, threonine 13.3wt%, cosmetic grade, wheat to soybean amino acid ratio is 1:1, serine + threonine total 26.6%).

[0094] Carrier: 70.0 parts deionized water (conductivity ≤5μS / cm), 10.0 parts glycerin (cosmetic grade, ≥99.5%), 5.0 parts 1,3-propanediol (cosmetic grade, ≥99.0%);

[0095] Additives: 0.8 parts polyglycerol-10 laurate (emulsifier), 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0096] The preparation method is as follows:

[0097] S1. Add 35.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol to a clean mixing tank, and stir magnetically at 260 rpm for 20 min at 29°C. Slowly add the hydrolyzed vegetable protein solution and continue stirring for 12 min until it is transparent and homogeneous.

[0098] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, and stir at 280 rpm for 5 min until completely dispersed; add the biomimetic amino acid complex in three portions, and continue stirring for 8 min; add 10% lactic acid solution dropwise to adjust the pH to 6.0, and stir for 5 min;

[0099] S3. Slowly add the S1 solution along the container wall to the S2 solution, and stir at 230 rpm for 25 min; when the temperature drops to 30℃, add the preservative, and when the temperature reaches 28℃, add the flavoring, and stir evenly for 6 min;

[0100] S4. Place in an environment of 20-25℃ and let stand and cool for 50 minutes. Filter through a 100-mesh stainless steel sieve and test the appearance, pH value (6.0), viscosity and microbial indicators. Fill after passing the test.

[0101] Example 6

[0102] This embodiment discloses a hair perming damage repair composition, comprising the following components in parts by weight:

[0103] Hydrolyzed plant protein: 0.5 parts (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0104] Bionic amino acid complex: 1.0 part (wheat amino acids 30wt%, soybean amino acids 30wt%, arginine hydrochloride 13.4wt%, serine 13.3wt%, threonine 13.3wt%, cosmetic grade, wheat to soybean amino acid ratio is 1:1, serine + threonine total 26.6%).

[0105] Carrier: 70.0 parts deionized water (conductivity ≤5μS / cm), 10.0 parts glycerin (cosmetic grade, ≥99.5%), 5.0 parts 1,3-propanediol (cosmetic grade, ≥99.0%);

[0106] Additives: 0.8 parts polyglycerol-10 laurate (emulsifier), 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0107] The preparation method is as follows:

[0108] S1. Add 35.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol to a clean stirred tank, and stir magnetically at 240 rpm for 15 min at 30°C. Slowly add the hydrolyzed vegetable protein solution and continue stirring for 12 min until clear and homogeneous.

[0109] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, and stir at 280 rpm for 5 min until completely dispersed; add the biomimetic amino acid complex in three portions, and continue stirring for 8 min; add 10% lactic acid solution dropwise to adjust the pH to 5.3, and stir for 5 min;

[0110] S3. Slowly add solution S1 to solution S2 and stir at 230 rpm for 25 min; add preservative when the temperature drops to 30℃, add flavoring when the temperature reaches 28℃, and stir evenly for 6 min.

[0111] S4. Place in an environment of 20-25℃ and let stand for 60 minutes. Filter through a 100-mesh stainless steel sieve and test the appearance, pH value (5.3), viscosity and microbial indicators. Fill after passing the test.

[0112] Comparative Example 1

[0113] This comparative example discloses a hair perming damage repair composition that does not contain hydrolyzed plant protein, comprising the following components in parts by weight:

[0114] Bionic amino acid complex: 1.0 part (wheat amino acids 30wt%, soybean amino acids 30wt%, arginine hydrochloride 13.4wt%, serine 13.3wt%, threonine 13.3wt%, cosmetic grade, wheat to soybean amino acid ratio is 1:1, serine + threonine total 26.6%).

[0115] Carrier: 72.0 parts of deionized water (conductivity ≤5μS / cm), 10.0 parts of glycerin (cosmetic grade, ≥99.5%), and 5.0 parts of 1,3-propanediol (cosmetic grade, ≥99.0%).

[0116] Additives: 0.8 parts polyglycerol-10 laurate (emulsifier), 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0117] The preparation method is as follows:

[0118] S1. Add 36.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol to a clean stirred tank, and stir magnetically at 250 rpm for 15 min at 28°C;

[0119] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, and stir at 280 rpm for 5 min; add the biomimetic amino acid complex in three portions, and continue stirring for 8 min; add 10% lactic acid solution dropwise to adjust the pH to 5.2, and stir for 5 min;

[0120] S3. Slowly add the solution obtained in S1 to the solution in S2 and stir at 230 rpm for 25 min; when the temperature drops to 30℃, add the preservative and when the temperature reaches 28℃, add the flavoring and stir evenly for 6 min.

[0121] S4. Allow to cool at 20-25℃ for 40 minutes, filter through a 100-mesh stainless steel sieve, and test for appearance, pH value (5.2), viscosity and microbial indicators. Fill after passing the test.

[0122] Comparative Example 2

[0123] This comparative example discloses a hair perming damage repair composition that does not contain a biomimetic amino acid complex, comprising the following components in parts by weight:

[0124] Hydrolyzed plant protein: 0.5 parts (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0125] Carrier: 72.0 parts of deionized water (conductivity ≤5μS / cm), 10.0 parts of glycerin (cosmetic grade, ≥99.5%), and 5.0 parts of 1,3-propanediol (cosmetic grade, ≥99.0%).

[0126] Additives: 0.8 parts polyglycerol-10 laurate (emulsifier), 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0127] The preparation method is as follows:

[0128] S1. Add 36.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol to a clean stirred tank, and stir magnetically at 250 rpm for 15 min at 28°C. Slowly add the hydrolyzed vegetable protein solution and continue stirring for 12 min until transparent.

[0129] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, stir at 280 rpm for 5 min; add 10% lactic acid solution dropwise to adjust the pH to 5.2, stir for 5 min;

[0130] S3. Slowly add the solution obtained in S1 to the solution in S2 and stir at 230 rpm for 25 min; when the temperature drops to 30℃, add the preservative and when the temperature reaches 28℃, add the flavoring and stir evenly for 6 min.

[0131] S4. Allow to cool at 20-25℃ for 40 minutes, filter through a 100-mesh stainless steel sieve, and test for appearance, pH value (5.2), viscosity and microbial indicators. Fill after passing the test.

[0132] Comparative Example 3

[0133] This comparative example discloses a hair-damage repair composition for permed hair where the ratio of wheat amino acids to soybean amino acids in a biomimetic amino acid complex does not fall within a defined range, comprising the following components in parts by weight:

[0134] Hydrolyzed plant protein: 0.5 parts (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0135] Biomimetic amino acid complex: 1.0 part (wheat amino acids 20wt%, soybean amino acids 60wt%, arginine hydrochloride 10wt%, serine 5wt%, threonine 5wt%, cosmetic grade; wherein the ratio of wheat to soybean amino acids is 1:3);

[0136] Carrier: 72.0 parts of deionized water (conductivity ≤5μS / cm), 10.0 parts of glycerin (cosmetic grade, ≥99.5%), and 5.0 parts of 1,3-propanediol (cosmetic grade, ≥99.0%).

[0137] Additives: 0.8 parts polyglycerol-10 laurate (emulsifier), 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0138] The preparation method is as follows:

[0139] S1. Add 36.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol to a clean mixing tank, and stir magnetically at 250 rpm for 15 min at 28°C. Slowly add the hydrolyzed vegetable protein solution and continue stirring for 12 min until transparent.

[0140] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, and stir at 280 rpm for 5 min; add the biomimetic amino acid complex in three portions, and continue stirring for 8 min; add 10% lactic acid solution dropwise to adjust the pH to 5.2, and stir for 5 min;

[0141] S3. Slowly add solution S1 to solution S2 and stir at 230 rpm for 25 min; add preservative when the temperature drops to 30℃, add flavoring when the temperature reaches 28℃, and stir evenly for 6 min.

[0142] S4. Allow to cool at 20-25℃ for 40 minutes, filter through a 100-mesh stainless steel sieve, and test for appearance, pH value (5.2), viscosity and microbial indicators. Fill after passing the test.

[0143] Comparative Example 4

[0144] This comparative example discloses a finished hair perming damage repair composition with a pH value exceeding a defined range, comprising the following components in parts by weight:

[0145] Hydrolyzed plant protein: 0.5 parts (average molecular weight <3500 Da, obtained by sequential enzymatic hydrolysis of moringa seed protein with papain, trypsin and neutral protease, aqueous solution with solid content of 14-17%, cosmetic grade);

[0146] Bionic amino acid complex: 1.0 part (wheat amino acids 30wt%, soybean amino acids 30wt%, arginine hydrochloride 13.4wt%, serine 13.3wt%, threonine 13.3wt%, cosmetic grade, wheat to soybean amino acid ratio is 1:1, serine + threonine total 26.6%).

[0147] Carrier: 72.0 parts of deionized water (conductivity ≤5μS / cm), 10.0 parts of glycerin (cosmetic grade, ≥99.5%), and 5.0 parts of 1,3-propanediol (cosmetic grade, ≥99.0%).

[0148] Additives: 0.8 parts polyglycerol-10 laurate (emulsifier), 0.8 parts phenoxyethanol / ethylhexylglycerin compound preservative, and 0.2 parts fragrance.

[0149] The preparation method is as follows:

[0150] S1. Add 36.0 parts of deionized water, 5.0 parts of glycerol and 2.5 parts of 1,3-propanediol to a clean stirred tank, and stir magnetically at 250 rpm for 15 min at 28°C. Slowly add the hydrolyzed vegetable protein solution and continue stirring for 12 min until transparent.

[0151] S2. Add the remaining carrier to another container, add 0.8 parts of polyglycerol-10 laurate, and stir at 280 rpm for 5 min; add the biomimetic amino acid complex in three portions, and continue stirring for 8 min; add 10% sodium hydroxide solution dropwise to adjust the pH to 7.0, and stir for 5 min.

[0152] S3. Slowly add solution S1 to solution S2 and stir at 230 rpm for 25 min; add preservative when the temperature drops to 30℃, add flavoring when the temperature reaches 28℃, and stir evenly for 6 min.

[0153] S4. Allow to cool at 20-25℃ for 40 minutes, filter through a 100-mesh stainless steel sieve, and test for appearance, pH value (7.0), viscosity and microbial indicators. Fill after passing the test.

[0154] Comparative Example 5

[0155] This comparative example is largely the same as Example 1, except that the hydrolyzed plant protein is a hydrolysate obtained by hydrolyzing moringa seed protein with papain.

[0156] Comparative Example 6

[0157] This comparative example discloses a formula and preparation method for a commercially available conventional hair conditioner as a control sample. The hair conditioner used is Pantene Silky Smooth Conditioner.

[0158] Performance testing

[0159] 1. Disulfide bond repair capability (FTIR-ATR infrared spectroscopy)

[0160] Sample preparation: Take healthy Caucasian hair bundles (2.0g per bundle) that have undergone double bleaching treatment, and perform a standard use treatment once with the compositions of Examples 1-6 and Comparative Examples 1-5 (0.2g / bundle, leave for 5min, rinse to remove residue, and blow dry at room temperature).

[0161] Testing steps:

[0162] (1) At 1040cm -1 The absorbance of cysteine ​​sulfonic acid (Cys-SO3H) on the sample surface was measured at wavenumber.

[0163] (2) Using unbleached healthy hair strands as the baseline (referred to as 0% damage) and bleached untreated hair strands as the damage control (referred to as 100% damage).

[0164] (3) Calculate the percentage decrease in absorbance of the treated hair strand relative to the bleached damaged hair strand. The greater the decrease, the more the cysteine ​​sulfonic acid content is reduced, that is, the higher the degree of disulfide bond repair.

[0165] The test results are shown in Table 1 below.

[0166] Table 1

[0167]

[0168]

[0169] Conclusion: All examples were significantly superior to the comparative examples; Example 6 was the best (44.2%), demonstrating that the "moringa seed protein hydrolysate + biomimetic amino acid complex" achieved the most complete reversal of broken disulfide bonds under reasonable pH (4.5-6.5) and optimized component ratios. The repair rate was significantly reduced when any core component was missing or the ratio deviated, when hydrolyzed by non-specific enzymes, or when the pH was abnormal (Comparative Examples 1 / 2 / 3 / 4 / 5); the commercially available hair conditioner (Comparative Example 6) only showed improved surface smoothness, with limited disulfide bond repair.

[0170] Although Comparative Example 6 (commercially available conditioner) has a certain repairing effect, it is far less effective than the full formulation examples of this invention.

[0171] Same as the aforementioned FTIR-ATR test: bleached hair strands (damaged control), healthy hair strands (baseline), and hair strands treated with Examples 1-6 and Comparative Examples 1-5, respectively.

[0172] 2. Detection of disulfide bond formation (FTIR-ATR infrared spectroscopy)

[0173] FTIR-ATR: Recording at 500-600 cm⁻¹ -1 Spectral variations within the range. At 525 cm⁻¹ -1 At this location, the stretching vibration of the -SS- disulfide bond exhibits a characteristic absorption peak, and the increase in absorbance indicates the recovery of disulfide bond content.

[0174] Raman spectra: in the range of 490-520 cm⁻¹ -1 Signal was acquired in intervals of 509cm. -1 The Raman scattering peaks that appear are characteristic signals of disulfide vibrations. Higher peak intensities indicate more complete disulfide bond reconstruction.

[0175] 525cm of bleached damaged hair -1 With 509cm -1 Peak intensity was set to 0% recovery, and healthy hair strands were set to 100% reference value. The relative recovery rate of each treated sample was calculated.

[0176] The test results are shown in Tables 2-1 and 2-2 below.

[0177] Table 2-1

[0178]

[0179]

[0180] Table 2-2

[0181] sample relative peak intensity Recovery rate (%) Healthy hairline (benchmark) 1 100 Bleaching damage control 0.45 0 Example 1 0.74 52.7 Example 2 0.77 58.2 Example 3 0.79 61.8 Example 4 0.81 65.5 Example 5 0.84 70.9 Example 6 0.86 74.5 Comparative Example 1 0.63 32.7 Comparative Example 2 0.6 27.3 Comparative Example 3 0.68 41.8 Comparative Example 4 0.58 23.6 Comparative Example 5 0.69 42.2 Comparative Example 6 0.66 38.2

[0182] 3. Keratin integrity (differential scanning calorimetry)

[0183] Sample preparation: Bleached hair strands and treatment methods for the same examples / comparative examples as those used in the FTIR-ATR test.

[0184] Test parameters: nitrogen atmosphere, heating rate 10℃ / min.

[0185] Testing steps:

[0186] (1) Take about 5 mg of dried hair and place it in an aluminum crucible and seal it.

[0187] (2) The heating range was 30-300℃, and the endothermic peak area (J / g) at 236℃ (external hydrogen bond breaking) and 252℃ (internal hydrogen bond breaking / keratin denaturation) was recorded.

[0188] (3) The larger the peak area, the more stable the structure at that temperature and the higher the keratin integrity.

[0189] The test results are shown in Table 3 below.

[0190] Table 3

[0191]

[0192] Conclusion: The improvements in the examples showed a stepwise increase, with example 6 being closest to healthy hair strands; the improvements in comparative examples 1 / 2 / 4 were limited, confirming that the core two-component system and appropriate pH are crucial for the restoration of keratin structural stability.

[0193] 4. Tensile properties (tensile strength test)

[0194] Sample preparation: Bleached hair strands and treatment methods are the same as those used in the FTIR-ATR test.

[0195] Test parameters: test length 20mm, tensile speed 20mm / min, humidity 50±2%RH, temperature 23±2℃.

[0196] Testing indicators:

[0197] Total work (mJ): The area under the stress-strain curve from initial stress to fracture, reflecting the overall fracture resistance.

[0198] 25% strain stress (mN): reflects elasticity and toughness.

[0199] The test results are shown in Table 4 below.

[0200] Table 4

[0201]

[0202]

[0203] Conclusion: The overall improvement of the examples is significant. Example 6 shows a 42% increase in total work and a 42% increase in strain stress compared to the bleaching control. The comparative examples show only a slight improvement, indicating that inner layer bonding repair (protein / amino acid) is more effective in restoring strength and elasticity than surface film formation.

[0204] 5. Dry and wet combing performance

[0205] Sample preparation: Bleached hair strands were treated once in the examples / comparative examples, and tested in both wet and dry states.

[0206] Testing steps:

[0207] Wet combing test: The sample was immersed in water for 1 minute, combing speed was 100 mm / min, and the peak combing force (N) was recorded.

[0208] Dry combing test: The sample was naturally dried for 24 hours and then tested under the same conditions.

[0209] The test results are shown in Table 5 below.

[0210] Table 5

[0211] Sample number Wet combing force (N) Dry combing force (N) Healthy hairline (benchmark) 1.05 0.8 Bleaching damage control 2.4 1.9 Example 1 1.82 1.46 Example 2 1.72 1.41 Example 3 1.7 1.39 Example 4 1.66 1.37 Example 5 1.6 1.35 Example 6 1.58 1.33 Comparative Example 1 2.15 1.72 Comparative Example 2 2.18 1.75 Comparative Example 3 1.95 1.55 Comparative Example 4 2.2 1.78 Comparative Example 5 1.92 1.53 Comparative Example 6 1.98 1.54

[0212] Conclusion: Examples 5 / 6 approached the level of healthy hair strands; Comparative Examples 1 / 2 / 4 had unsatisfactory lubrication / untangling effects due to poor active penetration and pH conditions.

[0213] 6. High-temperature thermal damage protection

[0214] Sample preparation: Bleached hair strands were treated once in the example / comparative examples, dried, and then clamped 5 times under BaBylissPRO straightener (230℃).

[0215] Testing steps:

[0216] After heat treatment, the material was cooled to room temperature, and the total work and breaking load were determined according to the tensile property method.

[0217] Calculate the retention rate (%) compared to the same batch of samples before heat treatment.

[0218] The test results are shown in Table 6 below.

[0219] Table 6

[0220] Sample number Breaking load retention rate (%) Overall power retention rate (%) Healthy hairline (benchmark) 100 100 Bleaching damage control 58 55 Example 1 73 70 Example 2 75 72 Example 3 76 73 Example 4 78 74 Example 5 79 75 Example 6 80 76 Comparative Example 1 65 62 Comparative Example 2 64 61 Comparative Example 3 69 66 Comparative Example 4 63 60 Comparative Example 5 69 67 Comparative Example 6 68 65

[0221] Conclusion: The performance of the examples improved stepwise with increasing formulation and pH optimization. Example 6 maintained 80% fracture load and 76% total work after 230°C. Comparative Example 4 (pH=7.0) had the lowest performance, confirming that a weakly acidic environment is crucial for bond repair and thermal stability.

[0222] The above description is merely a preferred embodiment of the present invention. The scope of protection of the present invention is not limited to the above embodiments. All technical solutions falling within the scope of the present invention's concept are within the scope of protection of the present invention. It should be noted that for those skilled in the art, any improvements and modifications made without departing from the principles of the present invention should also be considered within the scope of protection of the present invention.

Claims

1. A hair repair composition for permed hair, characterized in that, The components include the following parts by weight: Hydrolyzed vegetable protein: 0.02–1.0 parts; Biomimetic amino acid complex: 0.1–2.0 parts; The biomimetic amino acid complex includes at least wheat amino acids, soybean amino acids, arginine hydrochloride, serine, and threonine; Carrier: 50–95 copies; Additives: 0.5–15 parts; The hydrolyzed plant protein is obtained by enzymatic hydrolysis of Moringa seed protein; The biomimetic amino acid complex comprises, by weight percentage, 30 wt% wheat amino acids, 30 wt% soybean amino acids, 13.4 wt% arginine hydrochloride, 13.3 wt% serine, and 13.3 wt% threonine; The weight ratio of the hydrolyzed plant protein to the biomimetic amino acid complex is 0.2:1 to 10:1; The average molecular weight of the hydrolyzed plant protein is less than 3,500 Daltons; The pH value of the composition is 4.5 to 6.5; The hydrolyzed plant protein is obtained by sequentially hydrolyzing moringa seed protein with papain, trypsin, and neutral protease.

2. The hair repair composition according to claim 1, characterized in that, Its preparation method includes the following steps: S1. Dissolve hydrolyzed plant protein in a portion of the carrier and stir at 200-400 rpm for 10-30 minutes at 25℃-35℃; S2. Dissolve the biomimetic amino acid complex in the remaining carrier and adjust the pH to 4.5–6.5; S3. Mix the solutions obtained in step S1 and step S2, add the additive, and stir at 200-500 rpm for 20-40 minutes at 25℃-35℃. S4. Cool to room temperature to obtain the finished product of the hair damage repair composition.

3. The hair perming damage repair composition according to claim 2, characterized in that, Both steps S1 and S3 involve stirring using magnetic stirring, and the cooling process is completed by standing for 30 to 60 minutes at an ambient temperature of 20°C to 25°C.

Images