Preparation equipment and process of keratin silk peptide nano-emulsion for pet hair repair
Patent Information
- Application Number
- CN202511264606.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-05
- Publication Date
- 2025-11-21
AI Technical Summary
现有宠物毛发修复用角蛋白丝肽纳米乳液制备过程中,乳化效率低、乳液稳定性差和粒径分布不均,且传统方法耗时耗力,成本高,外界因素影响乳液稳定性。
采用预处理部件、缓冲离心部件、分离冷冻部件和干燥截留部件的集成设备,结合梯度降温技术和冷凝空气回收系统,实现角蛋白丝肽纳米乳液的连续化制备,通过螺旋蜗旋结构的离心阀体和内离心翼片组进行高效乳化与透析,负压环境保持物料稳定性,梯度降温保留活性成分。
显著提升了乳化均匀度,纳米乳液粒径分布控制在合理范围,提高了乳液稳定性和角蛋白活性,增强毛发修复效果,优化了制备过程的效率和成本。
Smart Images

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Abstract
Description
Technical Field
[0001] This invention relates to a device and process for preparing keratin silk peptide nanoemulsion for pet hair repair, belonging to the field of keratin silk peptide preparation technology. Background Technology
[0002] The main drawbacks in the emulsification stage of existing keratin silk peptide nanoemulsion preparation processes for pet hair repair include low emulsification efficiency, poor emulsion stability, and uneven particle size distribution. These drawbacks are typically related to the choice of emulsifier, emulsification process parameters, and the properties of the raw materials. Poor compatibility between the selected emulsifier and keratin silk peptides, or improper control of parameters such as stirring speed, time, and temperature during emulsification, will lead to unsatisfactory emulsification results. Conventional solutions include optimizing the selection of emulsifiers and adjusting emulsification process parameters. For example, choosing emulsifiers with better compatibility with keratin silk peptides, or determining the optimal stirring speed, time, and temperature through experiments. However, these methods have the disadvantage of potentially requiring extensive experimentation to screen for optimal conditions, which is time-consuming, labor-intensive, and costly. Pet hair repair products are affected by various external factors, such as temperature changes, light exposure, and chemical substances, which can further affect the stability and effectiveness of the emulsion. Therefore, there is an urgent need for a new equipment for preparing keratin silk peptide nanoemulsions for pet hair repair to address these issues. Summary of the Invention
[0003] To address the shortcomings of existing technologies, the present invention aims to provide a device for preparing keratin silk peptide nanoemulsion for pet hair repair, comprising: a feed pipe, an extraction component, a residue conveying component, and a connecting pipe, in order to solve the problems mentioned in the background art.
[0004] The technical solution of the present invention is implemented as follows: a keratin silk peptide nanoemulsion preparation device for pet hair repair, comprising: a pretreatment component and a condensate air recovery pipe, wherein a set of buffer centrifugation components for emulsifying and centrifuging keratin raw materials is provided on the right side of the pretreatment component, and a set of flow guide pipes for phase conversion and flow guidance of keratin raw materials is provided on the rear side of the buffer centrifugation component, wherein the flow guide pipes are sealed and connected to the buffer centrifugation component and the separation freezing component, and maintain a constant pressure state; The right side of the guide tube is provided with a set of separation and freezing components for phase inversion treatment of keratin silk peptide nanoemulsion. The upper right end of the separation and freezing components is provided with a set of drying and retention components for freeze-drying the nanoemulsion. The upper end of the drying and retention components is provided with a set of condensate recovery pipes for discharging and recovering the internal drying and cooling air. The interior of the drying and retention components is interconnected with the interior of the separation and freezing components.
[0005] In a preferred embodiment, the pretreatment component includes a power motor and a side feeding port. A coupling for outputting motor power is located on the right side of the power motor. The right side of the coupling is connected and fixed to the power motor, forming a power conversion connection. A base for stable support is located at the lower end of the power motor. The base is connected and fixed to the lower end of the power motor by several sets of bolts. A support base for stable support and expanding the support area is located at the lower end of the base. The support base and the base are interlocked, positioning the lower end of the base and the inner side of the upper end of the support base in a locked state. A centrifugal valve for preliminary centrifugation and dialysis of keratin materials is located on the right side of the coupling.
[0006] In a preferred embodiment, the centrifugal valve body has a set of inlets on the front side for introducing external keratin material, and a set of outlets on the rear side for desalting the keratin material after centrifugation. The front cross-section of the centrifugal valve body is a spiral structure. Inside the centrifugal valve body, there is a set of inner centrifugal blades for quickly mixing the keratin material with the clear liquid. The inner centrifugal blades form a spiral disc structure, and their center is connected to the outer right end of the coupling. The upper left and right sides of the centrifugal valve body each have a set of inner guide tubes for diverting and introducing external clear liquid. The two sets of inner guide tubes form a concave structure. At the center of the two sets of inner guide tubes, there is a centrifugal control valve for controlling the co-flow of external clear liquid. The centrifugal control valve is an electronic control valve. On the right side of the inner guide tube, there is a set of side feed ports for introducing external clear liquid, wherein the interior of the side feed ports is connected to the interior of the right inner guide tube. The internal guide tube on the left side is interconnected with the centrifugal valve body, which is in a negative pressure environment. A set of flow control valves for a sealed flow effect are installed at the connection points with the inlet and outlet. The outlet is sealed to the rear via a set of guide tubes. Both the inlet and outlet are flange structures. In practical use, by integrating pretreatment, centrifugal separation, and freeze-drying modules, continuous preparation of keratin silk peptide nanoemulsions is achieved. The pretreatment component uses a spiral centrifugal valve body with an internal centrifugal vane assembly to efficiently emulsify and dialysis keratin raw materials. The negative pressure environment ensures material flow stability. The buffer centrifugal component is connected to the separation and freezing system via a constant pressure sealed guide tube, ensuring the molecular structure integrity of the nanoemulsion during phase inversion. The separation and freezing component uses gradient cooling technology, combined with the condensate air recovery system of the drying and retention component, to effectively retain keratin active ingredients and improve emulsion stability.
[0007] In a preferred embodiment, the buffer centrifugal component includes a motor and an inner centrifugal feed tube. The left side of the motor is its drive end. A set of belts for transmitting power is provided on the outer side of the drive end. A set of centrifugal mixing cores for driving the inside of the feeding centrifugal tank to perform nano-emulsification centrifugal mixing is provided on the inner side of the lower end of the belts. A set of feeding centrifugal tanks for centrifugally mixing and emulsifying keratin substances is provided on the outer side of the left end of the centrifugal mixing cores. The inside of the feeding centrifugal tanks is a hollow structure. The centrifugal mixing cores inside the feeding centrifugal tanks are penetrated by a rotating shaft through the center of the left end of the feeding centrifugal tanks. A set of positioning bearings for maintaining stable rotation is provided at the penetration position of the rotating shaft and the feeding centrifugal tanks. The left side of the rotating shaft is connected and fixed to the center of the drive wheel. A set of side-stabilizing support plates for maintaining its position is provided on the outer side of the positioning bearings. The side-stabilizing support plates are fixed to the feeding centrifugal tanks by bolts.
[0008] In a preferred embodiment, the lower left side of the feeding centrifuge tank is provided with a set of funnel-shaped seepage chambers. The lower end of the seepage chambers is provided with a set of lower guide pipes for seeping the liquid material of the keratin centrifuged mixture. The lower end of the lower guide pipes is provided with a set of primary recovery boxes for recycling the material. The lower end of the primary recovery boxes is provided with a set of lower collection pipes for guiding the material inside. The right side of the feeding centrifuge tank is provided with a set of inner sealing plugs for maintaining material conduction inside. The middle of the inner side of the inner sealing plugs is sealed and penetrated by the centrifugal mixing core. The outer right side of the centrifugal mixing core is provided with a set of secondary centrifuge tanks for secondary centrifugal mixing. The secondary centrifuge tanks are the same size as the primary centrifuge tanks, and the right side of the centrifugal mixing core is located inside the secondary centrifuge tanks.
[0009] In a preferred embodiment, the secondary centrifuge tank has an inner sealing plug on its left side for fitting with the centrifugal mixing core. The upper right side of the secondary centrifuge tank has a second motor for scraping the keratin material inside, which is connected to a drive wheel via a belt. Both the primary and secondary centrifuge tanks have an inner settling chamber for centrifuging the keratin mixture. The lower right side of the left inner settling chamber and the lower left side of the right inner settling chamber each have a primary centrifuge outlet and a secondary centrifuge outlet for guiding the keratin mixture. A connecting conduit is provided between the primary and secondary centrifuge outlets for further guiding the keratin mixture in batches. Both connecting conduits are sealed to the primary and secondary centrifuge outlets, respectively. The outlet has several sets of electric heating wires wound in a ring for heating. Two sets of connecting conduits are connected to the inside of the guide tube and form a sealed space with the inside of the connecting conduit. At the same time, the inside of the guide tube is sealed to the feed inner tube. In actual use, motor one drives the active roller through the belt to rotate the centrifugal mixing core, so that the keratin raw material in the feed centrifuge tank one completes the primary nano-emulsification in the hollow structure. The positioning bearing and the side stabilizing support plate ensure the stability of operation. The seepage chamber and the lower guide tube one introduce the primary emulsion into the first-stage recovery box for preliminary separation. The inner sealing side plug prevents material leakage and maintains a negative pressure environment. The second-stage centrifuge tank is driven by motor two to achieve secondary centrifugation. Its internal static chamber, together with the centrifugal discharge port controlled by the electric heating wire, can adjust the separation accuracy. The sealed space formed by the connecting conduit and the guide tube can maintain the stability of the material phase. The second-stage recovery tube realizes the continuous collection of products. This design allows the keratin molecules to be gradually refined in the two centrifugation processes. The electric heating system can accurately control the separation temperature to avoid protein denaturation.
[0010] In a preferred embodiment, the centrifugal mixing core includes an embedded hole and an inner centrifugal flow ring cavity. The centrifugal mixing core is an integral roller-shaped structure, with an embedded hole in the middle. Inside the embedded hole is a set of drive shafts for power connection. Several sets of circulation holes for circulating the keratin centrifugal mixture liquid are distributed outside the embedded hole. A set of rotating wheels for maintaining the stability of the columnar rotation is located outside the circulation holes. Several sets of centrifugal blades for centrifugal flow of the keratin centrifugal mixture liquid are evenly distributed outside the rotating wheels. Each set of centrifugal blades has a support arm on its rear side for support. The support arm has an arc-shaped structure, and its inner side forms an isosceles triangle for support. The system consists of two sets of horizontally arranged support arms. Each set of support arms has a set of centrifugal blades on its front side for centrifuging the keratin centrifuged mixture. Several sets of centrifugal blades are arranged in a ring structure, forming a ring centrifugal flow channel for the keratin centrifuged mixture. In actual use, the roller structure and ring centrifugal flow channel design achieve efficient emulsification. The embedded holes and drive shaft work together to ensure stable power transmission. The circulation holes promote the axial circulation of the keratin solution, the rotor maintains rotational balance, and the centrifugal blades supported by the arc-shaped support arms form a multi-stage ring flow channel, causing the material to generate a spiral shearing motion under centrifugal force. This improves the emulsification uniformity by more than 30% compared to traditional stirring methods. The internal flow centrifugal ring cavity structure can avoid local eddies and ensure that the particle size distribution of the nanoemulsion is controlled within a reasonable and effective range.
[0011] In a preferred embodiment, the separation and freezing component includes a guide motor and an inner flow roller. The lower end of the guide motor is provided with a lower support frame for supporting and fixing it. The lower support frame is bolted to the guide motor and positions it. To the right of the guide motor is a guide seat for introducing the keratin centrifuged mixture liquid into the separation and freezing process. The guide seat has a hollow structure. At the front of the guide seat is an inner feed tube for exporting the external keratin centrifuged silk peptide mixture from the buffer centrifugation component. The inner feed tube is interconnected with the guide seat, and the flow path of the keratin centrifuged silk peptide mixture within the inner feed tube and the guide seat is at a right angle. To the right of the guide seat is an outer tube shell for exporting the keratin centrifuged silk peptide mixture. The right side of the guide motor is the drive end, which penetrates the center of both the guide seat and the outer tube shell. The outer tube shell contains a guide auger for step-feeding the keratin centrifuged silk peptide mixture.
[0012] In a preferred embodiment, the right side of the feed auger is provided with an emulsifying mixing chamber for mixing the centrifuged keratin silk peptide mixture with a 0.1 mol / L acetic acid solution. Inside the emulsifying mixing chamber, in the center, are several sets of feed guiding spirals for mixing the protein aqueous phase. These spirals are helical columnar structures with a thickness of 15-20 mm, and their flow surfaces are helically inclined, allowing them to mix the centrifuged keratin silk peptide mixture with the 0.1 mol / L acetic acid solution. The feed guiding spirals are magnetically rotated by external magnetic attraction. The outer side of the emulsifying mixing chamber is provided with a set of... The main tank is sealed and protected. A set of side response chamber doors is provided on the front side of the main tank for quick opening and active inspection of the interior. Two sets of fixing buckles are provided at the lower end of the side response chamber doors to keep them locked. A set of left connecting winglets is provided on the left side of the main tank for sealing the left side. A set of right connecting winglets is provided on the right side of the main tank for sealing the right side. Both the left and right connecting winglets are sealed and fixed inside the emulsification mixing chamber by means of flanges. A set of drying and retention components is provided at the upper right side of the main tank for freeze-drying the emulsified keratin and silk peptide substances.
[0013] In a preferred embodiment, the drying and retaining component is internally connected to the separating and freezing component. A vacuum compression freezing device for freezing the unemulsified keratin emulsion is located at the rear of the main tank. The main tank also contains several sets of annular external liquid nitrogen cooling conduits for cooling the emulsified keratin peptides with liquid nitrogen. An inner insulation layer is provided inside the main tank to prevent the liquid nitrogen cooling from failing. Several sets of internal turbulence rollers for cooling, drying, and stirring the emulsified keratin peptides are distributed in the middle of the feeding spiral. These internal turbulence rollers are evenly distributed inside the feeding spiral. A set of sealed bearings is located on the right side of the feeding spiral to maintain the stability of the internal turbulence rollers and the feeding spiral's rotation. These sealed bearings are connected to the center of the right connecting vane via a sealing bearing limiting connection. A set of... The cooling liquid nitrogen recovery pipe has a set of drying and retention components at the lower middle position for the emulsified keratin and silk peptide substances. In actual use, the relevant personnel use a guide motor to drive the guide auger to send the material into the emulsification mixing chamber through a right-angle guide path. The magnetically controlled guide screw promotes the uniform mixing of keratin and acetic acid solution with a 15-20mm spiral inclined surface. The main tank adopts a flange-sealed double-connecting wing structure, which, together with the side response chamber door, enables operation visibility. The vacuum compression freezing device and the liquid nitrogen cooling pipe form a gradient cooling system, allowing the material to complete the phase change in the range of -40℃ to -196℃. The inner turbulence roller creates a turbulent flow field inside the guide screw and effectively improves the freezing efficiency. The drying and retention components realize the recycling of liquid nitrogen through the condensate air recovery pipe. The sealed bearing ensures the continuous operation stability of the system under low temperature conditions.
[0014] In a preferred embodiment, the drying and intercepting component includes a sealing ring and a lower sealing socket. The lower end of the sealing ring is provided with a set of inner channel pipes for guiding liquid nitrogen cooling air through. Several sets of outer locking seats for sealing and engaging with the condensate air recovery pipe are distributed on the outer side of the upper end of the inner channel pipe. A set of inner flow control valves for controlling the flow and extraction of liquid nitrogen cooling air is provided at the middle of the rear side of the outer locking seats. A set of refrigerant compression tanks for introducing external liquid nitrogen into the storage tank is provided on the front side of the inner channel pipe. Three sets of diversion pipes for diverting liquid nitrogen refrigerant into the emulsion mixing chamber are provided at the upper end of the refrigerant compression tank.
[0015] In a preferred embodiment, the rear side of the diversion pipe is provided with three sets of pressure-resistant pipes for uniformly releasing liquid nitrogen. The front side of the pressure-resistant pipe is provided with a sealing inner liner for sealing connection with the inside of the diversion pipe. The right end of the inner channel pipe is provided with a control module for controlling the release degree of the refrigerant compression tank, the flow effect of the flow interruption control valve, and the liquid nitrogen recovery effect of the inner channel control valve. The control module is connected to the flow interruption control valve, the refrigerant compression tank, and the inner channel control valve via wires. The inside of the inner channel pipe is provided with several sets of diversion inner cavities for diverting liquid nitrogen. Each set of diversion inner cavities is provided with a filter for trapping and filtering impurities inside the liquid nitrogen. The inner permeation mesh, with its internal flow-blocking holes for liquid nitrogen flow and filtration, forms a double-sealing structure with the sealing ring and the outer locking seat in practical use, ensuring the airtightness of the liquid nitrogen delivery pipeline. The inner channel control valve and the flow-off control valve work together to regulate the flow of the refrigerant. The refrigerant compression tank distributes liquid nitrogen evenly to the pressure-resistant pipe through a three-part distribution pipe. The sealing inner liner effectively prevents low-temperature leakage. The control module integrates and manages the entire refrigeration cycle, monitoring the refrigerant release, recovery, and filtration process in real time. The inner permeation mesh in the distribution cavity can intercept impurities with a particle size greater than 5μm, ensuring the purity of the refrigerant and thus providing a stable low-temperature environment for the preparation of keratin nanomaterials.
[0016] A preparation process for a device for preparing keratin silk peptide nanoemulsion for pet hair repair includes the following steps: S1: First, the crude keratin raw material is centrifuged to obtain the supernatant and dialyzed to remove salt, and keratin silk peptides are obtained. Then, keratin and silk peptides are dissolved in 0.1 mol / L acetic acid solution at a mass ratio of 3:1 to form an 8% protein aqueous phase. Span80 and Tween80 are compounded at an HLB value of 10.5 and mixed with cyclohexane at a volume ratio of 1:4. S2: During the mixing process, the aqueous phase is slowly dripped into the organic phase under magnetic stirring, and the temperature is maintained at 35-42℃. Then, it is circulated three times under 45MPa pressure by a high-pressure homogenizer to form a colostrum with a particle size of 60-75nm. S3: Liquid nitrogen is compressed using a refrigerant compression tank, then released into the main tank and cooled with the keratin emulsion to be emulsified. After centrifugation and collection of the precipitate, 0.1% trehalose is added for freeze-drying protection, while simultaneously completing phase inversion drying. Then, the temperature is lowered to -40℃ at a rate of 1℃ / min and maintained for 2 hours, followed by drying at -55℃ and 10Pa for 24 hours. The final product has a water content of ≤5% as the basic standard.
[0017] After adopting the above technical solution, the beneficial effects of the present invention are as follows: by integrating modules such as pretreatment, centrifugal separation, and freeze drying, continuous preparation of keratin silk peptide nanoemulsion is realized. The pretreatment component adopts a centrifugal valve body with a spiral spiral structure and an inner centrifugal blade assembly, which can efficiently complete the emulsification and dialysis of keratin raw materials. The negative pressure environment ensures the stability of material flow. The buffer centrifugal component is connected to the separation and freezing system through a constant pressure sealed guide tube, so that the nanoemulsion maintains the molecular structure integrity during the phase transformation process. The separation and freezing component adopts gradient cooling technology and, together with the condensate air recovery system of the drying and retention component, can effectively retain the active ingredients of keratin and improve the stability of the emulsion. Motor 1 drives the main drive roller via belt to rotate the centrifugal mixing core, enabling the keratin raw material in the feed centrifuge tank 1 to complete primary nano-emulsification in the hollow structure. Positioning bearings and side stabilizing support plates ensure operational stability. The seepage chamber and lower guide pipe 1 guide the primary emulsion into the primary recovery box for preliminary separation. The inner sealing side plug prevents material leakage and maintains a negative pressure environment. The secondary centrifuge tank achieves secondary centrifugation by motor 2 driving the main drive roller 2. Its internal static chamber, combined with the centrifuge outlet controlled by the electric heating wire, can adjust the separation accuracy. The sealed space formed by the connecting conduit and the guide pipe can maintain the stability of the material phase. The secondary recovery pipe enables continuous collection of products. This design allows keratin molecules to be gradually refined during the two centrifugation processes. The electric heating system can precisely control the separation temperature to avoid protein denaturation. Efficient emulsification is achieved through a roller structure and annular centrifugal flow channel design. The embedded holes and drive shaft work together to ensure stable power transmission. The annular flow holes promote the axial circulation of the keratin solution. The swivel maintains rotational balance. The centrifugal blades supported by arc-shaped arms form a multi-stage annular flow channel, causing the material to generate a spiral shearing motion under centrifugal force. This improves the emulsification uniformity by more than 30% compared to traditional stirring methods. The internal flow centrifugal annular cavity structure can avoid local eddies and ensure that the particle size distribution of the nanoemulsion is controlled within a reasonable and effective range. The relevant personnel use a guide motor to drive the guide auger to send the material into the emulsification mixing chamber through a right-angle guide path. The magnetically controlled guide screw promotes the uniform mixing of keratin and acetic acid solution with a 15-20mm spiral inclined surface. The main tank adopts a flange-sealed double-connection wing structure, which, together with the side response chamber door, enables operation visibility. The vacuum compression freezing device and liquid nitrogen cooling pipe form a gradient cooling system, which enables the material to complete phase change in the range of -40℃ to -196℃. The internal turbulence roller creates a turbulent flow field inside the guide screw and effectively improves freezing efficiency. The drying and interception component realizes liquid nitrogen recycling through the condensate air recovery pipe. The sealed bearing ensures the continuous operation stability of the system under low temperature conditions. The sealing connection ring and the outer locking seat form a double sealing structure to ensure the airtightness of the liquid nitrogen delivery pipeline. The inner channel control valve and the flow cut-off control valve work together to regulate the flow of the refrigerant. The refrigerant compression tank distributes liquid nitrogen evenly to the pressure-resistant pipe through a three-part distribution pipe. The sealing inner liner effectively prevents low-temperature leakage. The control module integrates and manages the entire refrigeration cycle, and monitors the refrigerant release, recovery and filtration process in real time. The inner permeation mesh in the distribution cavity can intercept impurities with a particle size greater than 5μm, ensuring the purity of the refrigerant, thereby providing a stable low-temperature environment for the preparation of keratin nanomaterials.
[0018] The beneficial effects of this process after adopting the above technical solution are as follows: This process prepares 60-75nm nanoemulsions through high-pressure homogenization technology, which significantly improves the skin permeability of keratin silk peptides and enhances the hair repair effect. The optimized emulsifier compound and gradient freeze-drying technology work together to protect protein activity. The addition of trehalose effectively maintains the stability of the nanoemulsion. Liquid nitrogen freeze-drying combined with precise temperature control ensures that the final product has a water content of ≤5%, which preserves the function of repair factors for a long time, improves pet hair dryness and sensitivity problems, and restores the skin microecological balance. Attached Figure Description
[0019] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0020] Figure 1 This is a right oblique top view of the structure of a keratin silk peptide nanoemulsion preparation device for pet hair repair according to the present invention; Figure 2 This is a top view of the pretreatment component in a keratin silk peptide nanoemulsion preparation device for pet hair repair according to the present invention. Figure 3 This is a top view of the buffer centrifugation component in a keratin silk peptide nanoemulsion preparation device for pet hair repair according to the present invention. Figure 4 This is a top-view structural diagram of the left oblique front side of the buffer centrifuge component during separation at the middle position in the preparation device of keratin silk peptide nanoemulsion for pet hair repair according to the present invention. Figure 5 This is a top view of the right oblique front side of the centrifugal mixing core in the preparation device of keratin silk peptide nanoemulsion for pet hair repair according to the present invention. Figure 6 This is a top view of the right oblique front side of a structure of several sets of centrifugal mixing cores in a keratin silk peptide nanoemulsion preparation device for pet hair repair according to the present invention. Figure 7 This is a front view schematic diagram of the separation and freezing component in a keratin silk peptide nanoemulsion preparation device for pet hair repair according to the present invention; Figure 8 This is a top view of the right oblique front side structure of the guide spiral and several sets of inner flow rollers in the preparation equipment of keratin silk peptide nanoemulsion for pet hair repair according to the present invention. Figure 9 This is a schematic diagram of the front side structure of the active drying component during separation in a keratin silk peptide nanoemulsion preparation device for pet hair repair according to the present invention. In the diagram: 1-Pretreatment unit, 5-Buffer centrifuge unit, 6-Guide tube, 7-Separation and freezing unit, 8-Drying and interception unit, 9-Condensed air recovery tube; 11-Power motor, 12-Coupling, 13-Machine body base, 14-Support base, 15-Centrifugal valve body, 16-Centrifugal control valve, 17-External limit clamp, 18-Inlet, 19-Outlet, 101-Side feeding port; 51-Motor 1, 52-Belt, 53-Drive roller 1, 54-Feed centrifuge tank 1, 55-Side stabilizing support plate, 56-Primary recovery box, 57-Inner sealing side plug, 58-Primary centrifuge outlet, 59-Connecting conduit, 501-Secondary centrifuge inlet, 502-Secondary centrifuge tank, 503-Motor 2, 504-Drive roller 2, 505-Guide pipe, 506-Secondary recovery pipe, 507-Discharge port, 508-Inner centrifuge material pipe; 5a-Inset hole, 5b-Circulation hole, 5c-Rotator, 5d-Support arm, 5e-Centrifugal blade, 5f-Inner centrifugal annular cavity; 71-Guide motor, 72-Lower support frame, 73-Inner feed tube, 74-Outer tube shell, 75-Left connecting wing, 76-Main tank body, 77-Side response chamber door, 78-Fixing buckle, 79-Guide seat, 701-Lower support frame, 702-Guide auger, 703-Sealed bearing, 704-Inner flow roller; 81-Sealing connection ring, 82-External locking seat, 83-Internal channel control valve, 84-Refrigerant compression tank, 85-Diverter pipe, 86-Flow cut-off control valve, 87-Lower connecting flange seat, 88-Control module, 89-Sealing inner liner ring, 801-Pressure-resistant pipe, 802-Diverter inner cavity, 803-Inner permeable mesh, 804-Lower sealing socket. Detailed Implementation
[0021] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0022] Please see Figures 1-9 As an embodiment of the present invention: A device for preparing keratin silk peptide nanoemulsion for pet hair repair includes: a pretreatment component 1 and a condensed air recovery pipe 9. The right side of the pretreatment component 1 is provided with a set of buffer centrifugation components 5 for emulsifying and centrifuging keratin raw materials. The rear side of the buffer centrifugation components 5 is provided with a set of flow guide pipes 6 for phase conversion and flow guidance of keratin raw materials. The flow guide pipes 6 are sealed and connected to the buffer centrifugation components 5 and the separation and freezing components 7, and maintain a constant pressure. A set of separation and freezing components 7 for phase inversion treatment of keratin silk peptide nanoemulsion is provided on the right side of the flow guide tube 6. A set of drying and retention components 8 for freeze drying of nanoemulsion is provided on the upper right side of the separation and freezing components 7. A set of condensate recovery pipes 9 for discharging and recovering the internal drying and cooling air of the drying and retention components 8 is provided on the upper end of the drying and retention components 8. The interior of the drying and retention components 8 is connected to the interior of the separation and freezing components 7.
[0023] Please see Figure 1 , Figure 2 As a second embodiment of the present invention: based on the description in embodiment one, the pretreatment component 1 further includes a power motor 11 and a side feeding port 101. A set of couplings 12 for outputting motor power is provided on the right side of the power motor 11. The right side of the couplings 12 is connected and fixed to the power motor 11 to form a power conversion connection. A set of machine base 13 for stable support is provided at the lower end of the power motor 11. The machine base 13 is connected and fixed to the lower end of the power motor 11 by several sets of bolts. A set of support bases 14 for stable support and expanding the support area is provided at the lower end of the machine base 13. The support bases 14 and the machine base 13 are interlocked, and the lower end of the machine base 13 and the upper inner side of the support base 14 are positioned to each other and form a locking state. A set of centrifugal valves 15 for preliminary centrifugation and dialysis of keratin materials is provided on the right side of the couplings 12.
[0024] The centrifuge valve body 15 has a set of inlet ports 18 on the front side for introducing external keratin material, and a set of outlet ports 19 on the rear side for desalting the keratin material after centrifugation. The front cross-section of the centrifuge valve body 15 is a spiral structure. Inside the centrifuge valve body 15, there is a set of inner centrifuge blades for quickly mixing the keratin material with the clear liquid. The inner centrifuge blades form a spiral disc structure, and their center is connected to the outer right end of the coupling 12. On the upper left and right sides of the centrifuge valve body 15, there are sets of inner guide tubes for diverting and introducing external clear liquid. The two sets of inner guide tubes form a concave structure. At the center of the two sets of inner guide tubes, there is a centrifuge control valve 16 for controlling the co-flow of external clear liquid. The centrifuge control valve 16 is an electronic control valve. On the right side of the right inner guide tube, there is a set of side feed ports 101 for introducing external clear liquid. The side feed ports 101 are interconnected with the inside of the right inner guide tube. The interior of the pipe is interconnected with the interior of the centrifugal valve body 15, which is a negative pressure environment. A set of diversion control valves for sealing flow effect is provided at the connection points with the inlet 18 and the outlet 19. The rear side of the outlet 19 is sealed and connected to a set of guide pipes 6. Both the outlet 19 and the inlet 18 are flange structures. In actual use, by integrating modules such as pretreatment, centrifugal separation, and freeze drying, continuous preparation of keratin silk peptide nanoemulsion is realized. The pretreatment component 1 adopts a spiral centrifugal valve body 15 with an internal centrifugal blade assembly, which can efficiently complete the emulsification and dialysis of keratin raw materials. The negative pressure environment ensures the stability of material flow. The buffer centrifugal component 5 is connected to the separation and freezing system through a constant pressure sealed guide pipe 6, so that the nanoemulsion maintains the molecular structure integrity during the phase transformation process. The separation and freezing component 7 adopts gradient cooling technology, which, together with the condensate air recovery system of the drying and retention component 8, can effectively retain the active ingredients of keratin and improve the stability of the emulsion.
[0025] Please see Figure 1 , Figures 3-6As a third embodiment of the present invention: based on the description in embodiment one, the buffer centrifugal component 5 further includes a motor 51 and an inner centrifugal feed tube 508. The left side of the motor 51 is its drive end. A set of belts 52 for transmitting power is provided on the outer side of the drive end. A set of centrifugal mixing cores for driving the inside of the feeding centrifugal tank to perform nano-emulsification centrifugal mixing is provided on the inner side of the left end of the centrifugal mixing core. A set of feeding centrifugal tanks 54 for centrifugally mixing and emulsifying keratin substances is provided on the outer side of the left end of the feeding centrifugal tanks 54. The inside of the feeding centrifugal tanks 54 is a hollow structure. The centrifugal mixing core inside the feeding centrifugal tanks 54 passes through the center position of the left end of the feeding centrifugal tanks 54 through a rotating shaft. A set of positioning bearings for maintaining its stable rotation is provided at the position where the rotating shaft passes through the feeding centrifugal tanks 54. The left side of the rotating shaft is connected and fixed to the center position of the drive wheel. A set of side stabilizing support plates 55 for maintaining its position is provided on the outer side of the positioning bearings. The side stabilizing support plates 55 are fixed to the feeding centrifugal tanks 54 by bolts.
[0026] The lower left side of the feeding centrifuge tank 54 is provided with a set of funnel-shaped seepage chambers. At the lower end of the seepage chambers is a set of lower guide pipes 505 for seeping liquid substances of keratin centrifuged mixture. At the lower end of the lower guide pipes 505 is a set of primary recovery boxes 56 for recycling. At the lower end of the primary recovery boxes 56 is a set of lower collection pipes for guiding the internal substances. On the right side of the feeding centrifuge tank 54 is a set of inner sealing plugs 57 for maintaining the material conduction inside. The middle of the inner side of the inner sealing plugs 57 is sealed and penetrated by the centrifugal mixing core. On the outer right side of the centrifugal mixing core is a set of secondary centrifuge tanks 502 for secondary centrifugal mixing. The secondary centrifuge tanks 502 are the same size as the primary centrifuge tanks, and the right side of the centrifugal mixing core is located inside the secondary centrifuge tanks 502.
[0027] The secondary centrifuge tank 502 has an inner sealing plug 57 on its left side for fitting with the centrifugal mixing core. The upper right side of the secondary centrifuge tank 502 has a motor 503 for scraping the keratin material inside, which is connected to a drive wheel via a belt 52. Both the primary and secondary centrifuge tanks 502 have an inner settling chamber for centrifuging the keratin mixture. The lower right side of the left inner settling chamber and the lower left side of the right inner settling chamber each have a primary centrifuge outlet 58 and a secondary centrifuge outlet for guiding the keratin mixture. A connecting conduit 59 is provided between the primary and secondary centrifuge outlets for further diverting the keratin mixture. The two connecting conduits 59 are sealed to the primary centrifuge outlet 58 and the secondary centrifuge outlet, respectively. Several heating elements are annularly wound inside the primary and secondary centrifuge outlets. The heating wire has two sets of connecting conduits 59 that are respectively connected to the inside of the guide tube 505 and form a sealed space with the inside of the connecting conduit 59. At the same time, it is sealed to the feed inner tube 73 through the inside of the guide tube 505. In actual use, the motor 51 drives the drive roller through the belt 52 to rotate the centrifugal mixing core, so that the keratin raw material in the feed centrifuge tank 54 completes the primary nano-emulsification in the hollow structure. The positioning bearing and the side stabilizing support plate 55 ensure the stability of operation. The seepage chamber and the lower guide tube 505 guide the primary emulsion into the primary recovery box 5. 6. Initial separation is performed. The inner sealing side plug 57 prevents material leakage and maintains a negative pressure environment. The secondary centrifuge tank 502 achieves secondary centrifugation by driving the active power roller 504 through the motor 503. Its inner static chamber, combined with the centrifuge outlet controlled by the electric heating wire, can adjust the separation accuracy. The sealed space formed by the connecting conduit 59 and the guide pipe 505 can maintain the stability of the material phase. The secondary recovery pipe 506 realizes the continuous collection of products. This design allows keratin molecules to be gradually refined in the two centrifugation processes. The electric heating system can accurately control the separation temperature to avoid protein denaturation.
[0028] Please see Figure 5As a fourth embodiment of the present invention: Based on the description in embodiment three, the centrifugal mixing core further includes an embedded hole 5a and an inner flow centrifugal ring cavity 5f. The centrifugal mixing core is a roller-shaped structure. The embedded hole 5a is provided in the middle of the centrifugal mixing core. A set of transmission shafts for power connection is provided inside the embedded hole 5a. Several sets of circulation holes 5b for circulating the keratin centrifugal mixture liquid are distributed outside the embedded hole 5a. A set of rotating wheels 5c for maintaining the stability of the columnar rotation is provided outside the circulation holes 5b. Several sets of centrifugal blades 5e for centrifugal flow of the keratin centrifugal mixture liquid are evenly distributed outside the rotating wheels 5c. Several sets of centrifugal blades 5e are provided. Each set of centrifugal blades 5e has a set of support arms 5d for supporting it on the rear side. The support arms 5d are arranged in an arc shape, and the inner side of the support arms 5d forms an isosceles triangle. The structure supports the material, with two sets of horizontally arranged support arms 5d. Each set of support arms 5d has a set of centrifugal blades 5e on its front side for centrifuging the keratin centrifuged mixture. Several sets of centrifugal blades 5e are arranged in a ring structure, forming a ring centrifugal flow channel for the keratin centrifuged mixture. In actual use, the roller structure and the ring centrifugal flow channel design achieve efficient emulsification. The embedded hole 5a cooperates with the drive shaft to ensure stable power transmission. The circulation hole 5b promotes the axial circulation of the keratin solution. The wheel 5c maintains rotational balance. The centrifugal blades 5e supported by the arc-shaped support arms 5d form a multi-stage ring flow channel, causing the material to generate a spiral shearing motion under centrifugal force. This improves the emulsification uniformity by more than 30% compared to traditional stirring methods. The internal flow centrifugal ring cavity 5f structure can avoid local eddies and ensure that the particle size distribution of the nanoemulsion is controlled within a reasonable and effective range.
[0029] Please see Figure 7 , Figure 8As a fifth embodiment of the present invention: based on the description in embodiment one, the separation and freezing component 7 further includes a guide motor 71 and an inner flow roller 704. The lower end of the guide motor 71 is provided with a set of lower support frames 72 for supporting and fixing it. The lower support frames 72 are bolted to the guide motor 71 and position it. To the right of the guide motor 71 is a set of guide seats 79 for introducing the keratin centrifuged mixture liquid material into the separation and freezing process. The guide seat 79 has a hollow structure inside. At the front of the guide seat 79 is a set of guides for introducing the external keratin centrifuged mixture liquid material into the separation and freezing process. The keratin-centrifuged keratin mixture is discharged from the inner feed tube 73 inside the buffer centrifuge component 5. The inner feed tube 73 is connected to the inner feed seat 79. The flow path of the keratin-centrifuged keratin mixture inside the inner feed tube 73 and the inner feed seat 79 is a right-angle structure. On the right side of the inner feed seat 79, there is an outer tube shell 74 for discharging the keratin-centrifuged keratin mixture. The right side of the guide motor 71 is the drive end. The drive end passes through the inner feed seat 79 and the center of the inner tube shell 74. The inner tube shell 74 is equipped with a guide auger for step-by-step guiding of the keratin-centrifuged keratin mixture.
[0030] On the right side of the feed auger is an emulsification mixing chamber for mixing the centrifuged keratin and silk peptide mixture with a 0.1 mol / L acetic acid solution. Inside the emulsification mixing chamber, in the center, are several feed guide spirals 702 for mixing the protein aqueous phase. Each feed guide spiral 702 has a spiral columnar structure with a thickness of 15-20 mm. The flow surface of the feed guide spiral 702 has a spiral inclined structure, allowing it to mix the centrifuged keratin and silk peptide mixture with the 0.1 mol / L acetic acid solution. The feed guide spirals 702 rotate under magnetic attraction via an external magnetic guide. Outside the emulsification mixing chamber is a main tank for sealing and protection. The main tank 76 has a set of side response chamber doors 77 on its front side for quick opening and active inspection of its interior. The side response chamber doors 77 have two sets of locking buckles 78 at their lower ends for locking. The main tank 76 has a set of left connecting wing 75 on its left side for sealing its left side and a set of right connecting wing 75 on its right side for sealing its right side. Both the left and right connecting wing 75 and the right connecting wing 76 use flanges to seal and fix the interior of the emulsification mixing chamber. The upper right side of the main tank 76 has a set of drying and trapping components 8 for freeze-drying the emulsified keratin and silk peptide substances.
[0031] The drying and retention component 8 is internally connected to the separation and freezing component 7. A vacuum compression freezing device for freezing the unemulsified keratin emulsion is located at the rear of the main tank 76. The main tank 76 also contains several sets of annular external liquid nitrogen cooling conduits for cooling the emulsified keratin silk peptides with liquid nitrogen. An inner insulation layer is provided inside the main tank 76 to prevent the liquid nitrogen cooling from failing. Several sets of internal turbulence rollers are distributed in the middle of the guide spiral 702 to cool, dry, and stir the emulsified keratin silk peptides. These internal turbulence rollers are evenly distributed inside the guide spiral 702. A set of sealed bearings 703 is located on the right side of the guide spiral 702 to maintain the stability of the internal turbulence rollers and the rotation of the guide spiral 702. The sealed bearings 703 are connected to the center of the right connecting vane via a limiting connection. A set of liquid nitrogen for recovery is located at the upper right side of the drying and retention component 8. The condensate air recovery pipe 9 has a set of drying and retention components 8 at the lower middle position for the emulsified keratin and silk peptide substances. In actual use, the relevant personnel use the guide motor 71 to drive the guide auger to send the material into the emulsification mixing chamber through a right-angle guide path. The magnetically controlled guide screw 702 promotes the uniform mixing of keratin and acetic acid solution with a 15-20mm spiral inclined surface. The main tank 76 adopts a flange-sealed double-connecting wing structure, which, together with the side response chamber door 77, enables operation visibility. The vacuum compression freezing device and the liquid nitrogen cooling pipe form a gradient cooling system, so that the material completes the phase change in the range of -40℃ to -196℃. The inner turbulence roller forms a turbulent flow field inside the guide screw 702 and effectively improves the freezing efficiency. The drying and retention components 8 realize the recycling of liquid nitrogen through the condensate air recovery pipe 9. The sealed bearing 703 ensures the continuous operation stability of the system under low temperature conditions.
[0032] Please see Figure 9 As an embodiment of the present invention: based on the description in embodiment one, the drying and intercepting component 8 further includes a sealing connection ring 81 and a lower sealing inlet 804. The lower end of the sealing connection ring 81 is provided with a set of inner channel pipes for guiding liquid nitrogen cooling air through. Several sets of outer locking seats 82 for sealing and engaging with the condensate air recovery pipe 9 are distributed on the outer side of the upper end of the inner channel pipe. A set of inner flow control valves for controlling the flow and extraction of liquid nitrogen cooling air is provided at the middle position of the rear side of the outer locking seat 82. A set of refrigerant compression tanks 84 for introducing external liquid nitrogen into the storage is provided on the front side of the inner channel pipe. The upper end of the refrigerant compression tank 84 is provided with three sets of diversion pipes 85 for diverting liquid nitrogen refrigerant into the emulsion mixing chamber.
[0033] Three sets of pressure-resistant pipes 801 are provided on the rear side of the diversion pipe 85 for uniformly releasing liquid nitrogen. A sealing inner liner 89 is provided on the front side of the pressure-resistant pipe 801 for sealing connection with the inside of the diversion pipe 85. A control module 88 is provided at the right end of the inner channel pipe for controlling the release level of the refrigerant compression tank 84, the flow effect of the flow interruption control valve 86, and the liquid nitrogen recovery effect of the inner channel control valve 83. The control module 88 is connected to the flow interruption control valve 86, the refrigerant compression tank 84, and the inner channel control valve 83 via wires. Several sets of diversion inner cavities 802 are provided inside the inner channel pipe for diverting liquid nitrogen. Each diversion inner cavity 802 is provided with an internal permeation mesh 803 for intercepting and filtering impurities inside the liquid nitrogen. The permeable mesh 803 is an internal flow-blocking orifice used for the flow and filtration of liquid nitrogen. In actual use, the sealing connection ring 81 and the outer locking seat 82 form a double sealing structure to ensure the airtightness of the liquid nitrogen delivery pipeline. The inner channel control valve 83 and the flow-off control valve 86 work together to regulate the flow rate of the refrigerant. The refrigerant compression tank 84 distributes liquid nitrogen evenly to the pressure-resistant pipe 801 through the three-part distribution pipe 85. The sealing inner liner ring 89 effectively prevents low-temperature leakage. The control module 88 integrates and manages the entire refrigeration cycle, and monitors the refrigerant release, recovery and filtration process in real time. The inner permeable mesh 803 in the distribution cavity 802 can intercept impurities with a particle size greater than 5μm, ensuring the purity of the refrigerant, thereby providing a stable low-temperature environment for the preparation of keratin nanomaterials.
[0034] A preparation process for a device for preparing keratin silk peptide nanoemulsion for pet hair repair includes the following steps: S1: First, the crude keratin raw material is centrifuged to obtain the supernatant and dialyzed to remove salt, and keratin silk peptides are obtained. Then, keratin and silk peptides are dissolved in 0.1 mol / L acetic acid solution at a mass ratio of 3:1 to form an 8% protein aqueous phase. Span80 and Tween80 are compounded at an HLB value of 10.5 and mixed with cyclohexane at a volume ratio of 1:4. S2: During the mixing process, the aqueous phase is slowly dripped into the organic phase under magnetic stirring, and the temperature is maintained at 35-42℃. Then, it is circulated three times under 45MPa pressure by a high-pressure homogenizer to form a colostrum with a particle size of 60-75nm. S3: Liquid nitrogen is compressed using a refrigerant compression tank 84, and then released into the main tank 76. The liquid nitrogen is then cooled with the keratin emulsion to be emulsified. After centrifugation and collection of the precipitate, 0.1% trehalose is added for freeze-drying protection, while phase inversion drying is completed. The temperature is then lowered to -40℃ at a rate of 1℃ / min and maintained for 2 hours, and then dried at -55℃ and 10Pa for 24 hours. The final product has a water content of ≤5% as the basic standard.
[0035] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.
Claims
1. A device for preparing keratin silk peptide nanoemulsion for pet hair repair, comprising: The pretreatment component (1) and the condensate air recovery pipe (9) are characterized in that: a set of buffer centrifuge components (5) for emulsifying and centrifuging keratin raw materials is provided on the right side of the pretreatment component (1), and a set of guide pipes (6) for phase conversion and flow guidance of keratin raw materials is provided on the rear side of the buffer centrifuge component (5). The guide pipes (6) are sealed and connected to the buffer centrifuge component (5) and the separation and freezing component (7) and maintain a constant pressure. The right side of the guide tube (6) is provided with a set of separation freezing components (7) for phase inversion treatment of keratin silk peptide nanoemulsion. The upper right side of the separation freezing component (7) is provided with a set of drying interception components (8) for freeze-drying the nanoemulsion. The upper end of the drying interception component (8) is provided with a set of condensate recovery pipe (9) for discharging and recovering the internal drying and cooling air. The interior of the drying interception component (8) is interconnected with the interior of the separation freezing component (7).
2. The equipment for preparing keratin silk peptide nanoemulsion for pet hair repair according to claim 1, characterized in that: The pretreatment component (1) includes a power motor (11) and a side feeding port (101). A set of couplings (12) for outputting motor power is provided on the right side of the power motor (11). The right side of the couplings (12) is connected and fixed to the power motor (11) to form a power conversion connection. A set of machine bases (13) for stable support is provided at the lower end of the power motor (11). The machine bases (13) are connected and fixed to the lower end of the power motor (11) by several sets of bolts. A set of supports for stable support and expanding the support area is provided at the lower end of the machine bases (13). The base (14) and the support base (14) are fitted together, and the lower end of the machine base (13) and the inner side of the upper end of the support base (14) are positioned together and locked. The coupling (12) is provided with a set of centrifugal valves (15) for preliminary centrifugation and dialysis of keratin materials on the right side. The centrifugal valve (15) is provided with a set of feed inlets (18) for introducing external keratin materials on the front side. The centrifugal valve (15) is provided with a set of discharge outlets (19) for desalting the keratin materials after centrifugation on the rear side. The centrifugal valve (15) is provided with a horizontal cross-section on the front side. The cross-section is a spiral spiral structure. The centrifugal valve body (15) is equipped with a set of inner centrifugal blades for rapidly centrifuging and mixing keratin material with the clear liquid. The inner centrifugal blades form a spiral disc structure, and its center is connected to the outside of the right end of the coupling (12). The upper left and right sides of the centrifugal valve body (15) are respectively equipped with a set of inner guide tubes for diverting and introducing external clear liquid. The two sets of inner guide tubes form a concave structure. At the center of the two sets of inner guide tubes, there is a centrifugal control valve (16) for controlling the co-flow of external clear liquid. The centrifugal control valve (16) is an electronic control valve. The valve has a set of side feed ports (101) on the right side of the inner guide tube for introducing external clear liquid. The side feed ports (101) are connected to the inside of the right inner guide tube. The inside of the left inner guide tube is connected to the inside of the centrifugal valve body (15). The centrifugal valve body (15) is a negative pressure environment. A set of diversion control valves for sealing flow effect is provided at the connection points with the feed inlet (18) and the discharge port (19). The rear side of the discharge port (19) is sealed and connected to a set of guide tubes (6). The discharge port (19) and the feed inlet (18) are both flange structures.
3. The equipment for preparing keratin silk peptide nanoemulsion for pet hair repair according to claim 1, characterized in that: The buffer centrifugal component (5) includes a motor (51) and an inner centrifugal feed tube (508). The left side of the motor (51) is its drive end. A set of belts (52) for transmitting power is provided on the outside of the drive end. A set of centrifugal mixing cores for driving the inside of the feed centrifugal tank to perform nano-emulsification centrifugal mixing is provided on the inner side of the lower end of the belts (52). A set of feed centrifugal tanks (54) for centrifugally mixing and emulsifying keratin substances is provided on the outer side of the left end of the centrifugal mixing cores. The inside of the feed centrifugal tanks (54) is a hollow structure. The centrifugal mixing core inside the feed centrifugal tanks (54) is penetrated by a rotating shaft through the center of the left end of the feed centrifugal tanks (54). A set of positioning bearings for maintaining its stable rotation is provided at the penetration position of the rotating shaft and the feed centrifugal tanks (54). The left side of the rotating shaft is connected and fixed to the center of the drive wheel. A set of side support plates (55) for maintaining its position is provided on the outer side of the positioning bearings. The stabilizing support plate (55) is fixed to the feeding centrifuge tank (54) by bolts. The feeding centrifuge tank (54) has a set of funnel-shaped seepage chambers at the lower left end. The seepage chambers have a set of lower guide pipes (505) for seeping liquid substances of keratin centrifuged mixture at the lower end. The lower guide pipes (505) have a set of primary recovery boxes (56) for recycling them at the lower end. The primary recovery boxes (56) have a set of lower collection pipes for guiding the substances inside them at the lower end. The feeding centrifuge tank (54) has a set of inner sealing side plugs (57) for maintaining the material conduction inside it at the right side. The inner middle position of the inner sealing side plugs (57) is sealed and penetrated by the centrifugal mixing core. The centrifugal mixing core has a set of secondary centrifuge tanks (502) for secondary centrifugal mixing at the outer right end. The secondary centrifuge tanks (502) have the same specifications as the primary centrifuge tanks, and the right side of the centrifugal mixing core is located inside the secondary centrifuge tanks (502).
4. The equipment for preparing keratin silk peptide nanoemulsion for pet hair repair according to claim 3, characterized in that: The secondary centrifuge tank (502) has a set of inner sealing plugs (57) on the left side for fitting with the centrifugal mixing core. The upper right side of the secondary centrifuge tank (502) has a set of motors (503) for scraping the keratin material inside, which provides power. The motors (503) are connected to the drive wheel via belts (52). The primary centrifuge tank and the secondary centrifuge tank (502) each have a set of inner settling chambers for settling the keratin centrifugal mixture liquid material. The lower right side of the left inner settling chamber and the lower left side of the right inner settling chamber each have a set of inner settling chambers for settling the keratin centrifugal mixture liquid material. The primary centrifuge outlet (58) and the secondary centrifuge outlet are provided with a set of connecting conduits (59) between the primary centrifuge outlet (58) and the secondary centrifuge outlet for further batching of the keratin centrifuged mixture liquid. The two sets of connecting conduits (59) are respectively sealed to a primary centrifuge outlet (58) and a secondary centrifuge outlet. Several sets of electric heating wires for heating are wound in a ring inside the primary centrifuge outlet (58) and the secondary centrifuge outlet. The two sets of connecting conduits (59) form a sealed space with the inside of the guide tube (505) and the inside of the connecting conduit (59). The centrifugal mixing core is sealed and connected to the feed inner tube (73) through the guide tube (505). The centrifugal mixing core includes an embedded hole (5a) and an inner circulating centrifugal ring cavity (5f). The centrifugal mixing core is a roller-shaped structure. The embedded hole (5a) is provided in the middle of the centrifugal mixing core. A set of drive shafts for power connection is provided inside the embedded hole (5a). Several sets of circulation holes (5b) for circulating the keratin centrifugal mixture liquid are distributed outside the embedded hole (5a). A set of rotating wheels (5c) for maintaining the stability of the columnar rotation is provided outside the circulation holes (5b). Several sets of rotating wheels (5c) are evenly distributed outside the rotating wheels (5c) for maintaining the stability of the columnar rotation. Centrifugal blades (5e) are provided in several groups. Each group of centrifugal blades (5e) has a set of support arms (5d) on its rear side for supporting it. The support arms (5d) are arranged in an arc shape, and the inner side of the support arms (5d) forms an isosceles triangle structure to support it. There are two groups of support arms (5d) arranged in the same horizontal direction. Each group of support arms (5d) has a set of centrifugal blades (5e) on its front side for performing annular mixing and centrifugation of the keratin centrifugal mixture liquid material. The several groups of centrifugal blades (5e) are arranged in annular structure and form annular centrifugal flow channel for the keratin centrifugal mixture liquid material.
5. The equipment for preparing keratin silk peptide nanoemulsion for pet hair repair according to claim 1, characterized in that: The separation and freezing component (7) includes a guide motor (71) and an inner flow roller (704). The lower end of the guide motor (71) is provided with a set of lower support frames (72) for supporting and fixing it. The lower support frames (72) are fixed to the guide motor (71) by bolts and position the guide motor (71). The right side of the guide motor (71) is provided with a set of guide seats (79) for introducing the keratin centrifuged mixture liquid material into the separation and freezing process. The guide seat (79) has a hollow structure inside. The front side of the guide seat (79) is provided with a set of guides for introducing the external keratin centrifuged silk peptide mixture from the buffer. The inner feed tube (73) is led out from the core component (5). The inner feed tube (73) is connected to the inner feed seat (79). The flow path of the centrifuged keratin and silk peptide mixture in the inner feed tube (73) and the inner feed seat (79) is a right-angle structure. The right side of the inner feed seat (79) is provided with an outer tube shell (74) for leading out the centrifuged keratin and silk peptide mixture. The right side of the guiding motor (71) is the driving end. The driving end passes through the inner feed seat (79) and the center of the inner tube shell (74). The inner tube shell (74) is provided with a guiding auger for leading the centrifuged keratin and silk peptide mixture in a step-by-step manner.
6. The equipment for preparing keratin silk peptide nanoemulsion for pet hair repair according to claim 5, characterized in that: The right side of the feed auger is provided with an emulsification mixing chamber for mixing the centrifuged keratin silk peptide mixture with a 0.1 mol / L acetic acid solution. Inside the emulsification mixing chamber, in the middle position, are several sets of feed guide spirals (702) for mixing the protein aqueous phase. The feed guide spirals (702) are helical columnar structures with a thickness of 15-20 mm. The flow surface of the feed guide spirals (702) is a helical inclined structure, allowing them to mix the centrifuged keratin silk peptide mixture with the 0.1 mol / L acetic acid solution. The feed guide spirals (702) rotate under magnetic attraction via an external magnetic guide. Outside the emulsification mixing chamber, there is a main tank (76) for sealing and protecting it. (76) A set of side response chamber doors (77) are provided on the front side for quick opening and active inspection of the interior. The lower end of the side response chamber doors (77) is provided with two sets of fixing buckles (78) for locking the side response chamber doors (77). A set of left connecting wing pieces (75) for sealing the left side of the main tank (76) is provided on the left side. A set of right connecting wing pieces for sealing the right side of the main tank (76) is provided on the right side. Both the left connecting wing pieces (75) and the right connecting wing pieces are sealed and fixed inside the emulsification mixing chamber by means of flanges. A set of drying and retention components (8) for freeze-drying the emulsified keratin and silk peptide substances is provided on the upper right side of the main tank (76).
7. The equipment for preparing keratin silk peptide nanoemulsion for pet hair repair according to claim 6, characterized in that: The drying and trapping component (8) is internally connected to the separation and freezing component (7). A set of vacuum compression freezing devices for freezing the keratin emulsion to be emulsified is provided on the rear side of the main tank (76). The main tank (76) is also provided with several sets of external liquid nitrogen cooling conduits arranged in a ring structure to cool the emulsified keratin silk peptide material with liquid nitrogen. The main tank (76) is provided with an inner insulation layer of cotton to prevent the liquid nitrogen cooling effect from failing. Several sets of internal turbulence are distributed in the middle of the material guiding spiral (702) for cooling, drying and stirring the emulsified keratin silk peptide material. The inner turbulence rollers are evenly distributed inside the guide screw (702). A set of sealed bearings (703) is provided on the right side of the guide screw (702) to keep the inner turbulence rollers and the guide screw (702) rotating stably. The sealed bearings (703) are connected to the center of the right connecting vane by the sealed bearings (703). A set of condensate air recovery pipes (9) for recovering its coolant nitrogen is provided on the upper right side of the drying and retention component (8). A set of drying and retention components (8) for drying the emulsified keratin silk peptide material is provided at the lower middle position of the condensate air recovery pipe (9).
8. The equipment for preparing keratin silk peptide nanoemulsion for pet hair repair according to claim 7, characterized in that: The drying and intercepting component (8) includes a sealing connection ring (81) and a lower sealing inlet (804). The lower end of the sealing connection ring (81) is provided with a set of inner channel pipes for guiding liquid nitrogen cooling air through. The upper outer side of the inner channel pipe is provided with several sets of outer locking seats (82) for sealing and engaging with the condensate air recovery pipe (9). The middle position of the rear side of the outer locking seat (82) is provided with a set of inner flow control valves for controlling the flow and extraction of liquid nitrogen cooling air. The front side of the inner channel pipe is provided with a set of refrigerant compression tanks (84) for introducing external liquid nitrogen into storage. The upper end of the refrigerant compression tanks (84) is provided with three sets of diversion pipes (85) for diverting liquid nitrogen refrigerant into the emulsion mixing chamber. The rear side of the diversion pipes (85) is provided with three sets of pressure-resistant pipes (801) for uniformly releasing liquid nitrogen. The pressure-resistant pipe (801) is provided with a set of sealing inner liner rings (89) for sealing connection with the inside of the diversion pipe (85). The right end of the inner channel pipe is provided with a set of control modules (88) for controlling the release degree of the refrigerant compression tank (84), the flow effect of the flow interruption control valve (86), and the liquid nitrogen recovery effect of the inner channel control valve (83). The control module (88) is connected to the flow interruption control valve (86), the refrigerant compression tank (84), and the inner channel control valve (83) by wires. The inner channel pipe is provided with several sets of diversion inner cavities (802) for diverting liquid nitrogen. Each set of diversion inner cavities (802) is provided with an inner permeation mesh (803) for intercepting and filtering impurities in the liquid nitrogen. The inner permeation mesh (803) is used for the flow of liquid nitrogen and for filtering it.
9. A preparation process for a keratin silk peptide nanoemulsion preparation device for pet hair repair according to any one of claims 1-8, characterized in that: Includes the following steps: S1: First, the crude keratin raw material is centrifuged to obtain the supernatant and dialyzed to remove salt, and keratin silk peptides are obtained. Then, keratin and silk peptides are dissolved in 0.1 mol / L acetic acid solution at a mass ratio of 3:1 to form an 8% protein aqueous phase. Span80 and Tween80 are compounded at an HLB value of 10.5 and mixed with cyclohexane at a volume ratio of 1:
4. S2: During the mixing process, the aqueous phase is slowly dripped into the organic phase under magnetic stirring, and the temperature is maintained at 35-42℃. Then, it is circulated three times under 45MPa pressure by a high-pressure homogenizer to form a colostrum with a particle size of 60-75nm. S3: Use a refrigerant compression tank (84) to compress liquid nitrogen, then release the liquid nitrogen into the main tank (76) and cool it down with the keratin emulsion to be emulsified. After centrifugation and collection of precipitate, add 0.1% trehalose for freeze-drying protection and complete phase inversion drying. Then, first lower the temperature to -40℃ at a rate of 1℃ / min and keep it for 2 hours, and then dry it at -55℃ and 10Pa for 24 hours. The final product has a water content of ≤5% as the basic standard.