Traditional Chinese medicine composition for removing fatigue and treating osteoarthralgia as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention relates to a traditional Chinese medicine composition for removing fatigue and treating osteoarthralgia as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following components in parts by weight of dry substances in the raw materials: 20-60 parts of fig, 20-60 parts of cistanche, 0-10 parts of peach kernel and 0-20 parts of lalang grass rhizome. The preparation method comprises the step of mixing the components of the traditional Chinese medicine composition. The traditional Chinese medicine has the advantages of being good in qi and blood supplementing effect, capable of eliminating fatigue, quick in treatment effect on waist, shoulder, neck and knee joint pain, capable of quickly relieving the pain and good in treatment and healing effect.

Description

Technical Field

[0001] This invention relates to a traditional Chinese medicine composition for relieving fatigue and treating bone and joint pain, as well as its preparation method and application, belonging to the field of traditional Chinese medicine technology. Background Technology

[0002] Pain is a very common disease among the elderly, and it shows a clear trend of affecting younger people. It is often accompanied by symptoms such as fatigue, which seriously affects the quality of life and reduces health.

[0003] Traditional Chinese medicine theory identifies the following as the fundamental causes of pain: Qi stagnation: Qi flows smoothly; when Qi and blood do not circulate properly, pain occurs. Blood stasis: Poor blood flow and blockage are also common causes of pain; External pathogen invasion: The invasion of external pathogens can often cause pain; Insufficient Qi and blood can lead to insufficient nourishment of the ventricles of the brain, causing headaches. Disorders of liver and visceral function often cause pain.

[0004] Typical symptoms of bone and joint pain: Lower back pain: The lower back is the residence of the kidneys; if one cannot turn or move freely, the kidneys are weakened. Therefore, there is a long-standing saying that "kidney deficiency causes lower back pain," with kidney deficiency being the most common cause of lower back pain. In addition, exposure to cold and dampness, or heat and dampness, as well as falls and sprains leading to local blood and qi stagnation, are also common causes of lower back pain. Kidney deficiency, external pathogens, and blood stasis often occur together.

[0005] Cold and dampness: A heavy, cold pain in the lower back, difficulty turning over, gradually worsening, not relieved even by rest, and exacerbated by rainy weather; white, greasy tongue coating; deep pulse. Treatment: Dispel cold and dampness, warm the meridians and promote circulation.

[0006] Damp-heat: Lower back pain accompanied by a burning sensation, scanty and dark urine, or painful and difficult urination, tenderness upon palpation or percussion at the site of lower back pain, yellow and greasy tongue coating, and a soft and rapid pulse. Treatment should focus on clearing heat and resolving dampness.

[0007] Kidney deficiency: Characterized by persistent, dull aches and pains, weakness in the legs and knees, which worsens with exertion and improves when lying down. Those with a predominance of kidney yin deficiency may experience irritability, insomnia, seminal emission, hot palms and soles, a red tongue, and a thready, rapid pulse. Those with a predominance of kidney yang deficiency may present with a pale complexion, cold hands and feet, impotence, premature ejaculation, a pale tongue, and a deep, thready pulse. (The last sentence appears to be incomplete and possibly refers to tonifying the kidneys.)

[0008] Blood stasis: Low back pain caused by blood stasis is mostly due to traumatic injury or can also be caused by prolonged illness leading to blood stasis. The pain is like being pricked by a cone, fixed and不移, with mild cases causing difficulty in bending forward and backward, and severe cases resulting in inability to turn due to severe pain. The pain area is tender to pressure, the tongue is purplish and dark, or there are ecchymoses. Promote blood circulation to remove blood stasis and regulate qi to relieve pain. Low back pain in acute pyelonephritis, perinephric abscess, etc. mostly presents as damp-heat; low back pain in chronic pyelonephritis, renal tuberculosis is mainly due to kidney deficiency and often accompanied by damp-heat; low back pain in many chronic diseases such as chronic nephritis, nephroptosis, neurasthenia, etc. is mostly due to kidney deficiency; low back pain in rheumatoid arthritis, rheumatic arthritis, fibrositis, etc. is mostly due to cold-dampness or coexistence of kidney deficiency and cold-dampness; low back pain after trauma is mostly due to blood stasis, but kidney deficiency may also coexist over time.

[0009] Other joint pains: Joint pain is caused by wind-cold-damp pathogens invading the meridians or transforming into heat due to stagnation, resulting in obstruction of qi and blood circulation, so it is also called arthralgia syndrome. Promote blood circulation to dredge the collaterals. In addition, deficiency of qi and blood is often an internal cause that makes it easy for external pathogens to invade and obstruct the blood vessels.

[0010] Common diseases of bone and joint and nerve pain include: low back pain, cervical pain, scapulohumeral periarthritis pain, knee joint pain, etc. Currently, there is no good treatment measure. Western medicine mainly focuses on anti-inflammatory and analgesic effects, without specific drugs. The treatment measures are basically traction or physical therapy, with a long treatment cycle, great suffering for patients and easy to deteriorate. Severe cases require surgical treatment, which causes great damage to the patient's vitality; Chinese patent medicines, such as: Zhuangyao Jianshen Pills, Danlu Tongshen Tablets, have a long medication time but the effect is not obvious. Summary of the Invention

[0011] The object of the present invention is to provide a traditional Chinese medicine composition for relieving fatigue and treating bone and joint pain with quick effect and good effect, as well as its preparation method and application, aiming at bone and joint pain diseases such as cervical pain, low back pain, scapulohumeral periarthritis pain, knee joint pain, etc. and people prone to fatigue.

[0012] In order to achieve the above object, the present invention adopts the following technical solutions: A traditional Chinese medicine composition for relieving fatigue and treating bone and joint pain, calculated by weight parts of dry matter in the raw materials, the components of the traditional Chinese medicine composition include: 20-60 parts of Ficus carica, 20-60 parts of Cistanche deserticola, 0-10 parts of Prunus persica, and <0-20 parts of Imperata cylindrica.

[0013] The traditional Chinese medicine composition for relieving fatigue and treating bone and joint pain, calculated by weight parts of dry matter in the raw materials, the components of the traditional Chinese medicine composition include: 40-60 parts of Ficus carica, 40-60 parts. of Cistanche deserticola.

[0014] The traditional Chinese medicine composition for relieving fatigue and treating bone and joint pain, calculated by weight parts of dry matter in the raw materials, the components of the traditional Chinese medicine composition include: 20-60 parts of Ficus carica, 20-60 parts of Cistanche deserticola, 5-10 parts of Prunus persica, and 5-20 parts of Imperata cylindrica.

[0015] The Ficus carica and Cistanche deserticola are fresh or dried products; The Cistanche deserticola is dried Cistanche deserticola processed with wine, the fig is naturally fermented fig cake, the peach kernel is crushed wild peach kernel, and the Imperata cylindrica root is decocted in water. The traditional Chinese medicine composition can be formulated into any one of the following traditional Chinese medicine preparations: granules, decoctions, powders, pills, solutions, and capsules.

[0016] A method for preparing a traditional Chinese medicine composition for relieving fatigue and treating bone and joint pain: The components of the traditional Chinese medicine composition are mixed to obtain the final product.

[0017] The preparation method can be achieved by the following steps: (1) Raw material processing: Figs are dried at low temperature, vacuum packaged, frozen and fermented for more than 3 months, and then naturally fermented at room temperature for more than 3 months; Cistanche deserticola is peeled, washed, sliced ​​and dried, soaked in rice wine, yellow wine or white wine of 18° or above to fully absorb the wine, steamed and cooked and then dried to complete the wine-processed Cistanche deserticola; Peach kernels are made by crushing wild peach kernels; Imperata cylindrica root is decocted in water; (2) The processed raw materials are mixed according to the proportion to make traditional Chinese medicine preparations or beverages.

[0018] The low-temperature drying temperature for figs in step (1) is 40~60℃; In step (1), the temperature for frozen storage and fermentation of figs is -18 to -20°C. Preferably, the figs are frozen and fermented for more than 4 years; In step (1), the figs that are naturally fermented at room temperature can be composed of figs that have been frozen and fermented for more than 3 months, plus more than 10 wt% of figs that have been frozen and fermented for more than 4 years. In step (1), the temperature for natural fermentation of figs at room temperature is 30~60℃, and the water content of the fermented figs is ≤12%. The steaming and cooking time for Cistanche deserticola in step (1) is 2 to 6 hours.

[0019] The step (2) of mixing the processed raw materials according to the formula to make a traditional Chinese medicine beverage is as follows: the processed raw materials are mixed with 1 to 10 times the weight of water and then ground into a slurry.

[0020] The traditional Chinese medicine composition includes the product obtained by the above method.

[0021] The application of the traditional Chinese medicine composition in the preparation of traditional Chinese medicine preparations for relieving fatigue and treating osteoarthritis.

[0022] The beneficial effects of this invention are: it has a good effect on replenishing qi and blood, can eliminate fatigue, and is effective in treating bone and joint pain such as waist, shoulder, and neck. It can not only quickly relieve pain, but also has good therapeutic and curative effects. Detailed Implementation

[0023] To enable those skilled in the art to better understand the technical solution of the invention, the invention will be further described in detail below with reference to specific embodiments.

[0024] Cistanche deserticola is a common Chinese medicinal herb with various medicinal effects, mainly including the following: 1. Tonifying the kidneys and strengthening yang: This is one of the core effects of Cistanche deserticola. It can help improve problems such as soreness and weakness of the waist and knees, fear of cold, and decreased sexual function caused by insufficient kidney yang. It is often used to treat symptoms related to male kidney deficiency.

[0025] 2. Promotes bowel movement: Cistanche can promote intestinal peristalsis and relieve constipation caused by intestinal dryness, especially suitable for habitual constipation in middle-aged and elderly people or those with weak constitution.

[0026] 3. Nourishing essence and blood: For symptoms such as dizziness, weakness, and pale complexion caused by deficiency of essence and blood, Cistanche deserticola has a certain nourishing effect and can help nourish the body.

[0027] The Compendium of Materia Medica records that figs are sweet, neutral, and non-toxic; they can improve appetite, stop diarrhea, treat hemorrhoids, and sore throats. The Bible records in 1 Samuel 30:12 that David and his men found an Egyptian servant who had not eaten or drunk for three days and three nights and was on the verge of death. They gave him a piece of fig cake and two bunches of raisins, and after eating, he regained his strength. 2 Kings 20:7 records that King Hezekiah was seriously ill, and the prophet Isaiah commanded, “Bring a piece of fig cake.” They brought it and applied it to his wound, and the king was healed. Isaiah 38:21 contains a similar account.

[0028] Figs are a nutritious fruit with many health benefits, including the following: 1. Nutritional Supplement: Figs are rich in sugars, vitamins (such as vitamin C and B vitamins), minerals (such as calcium, iron, and potassium), and various amino acids, which can provide the human body with a variety of nutrients needed daily and help maintain normal physiological functions.

[0029] 2. Promotes digestion: It contains abundant dietary fiber and digestive enzymes such as protease. Dietary fiber can promote intestinal peristalsis, and digestive enzymes can help break down proteins in food, thereby promoting digestion and relieving constipation.

[0030] 3. Protects the cardiovascular system: The potassium in figs helps regulate blood pressure, and the various antioxidants they contain, such as polyphenols, can reduce free radical damage to blood vessels, thus providing some protection for cardiovascular health.

[0031] 4. Boost immunity: The rich nutrients, especially vitamins and minerals, help enhance the body's immune function and improve its ability to resist disease.

[0032] Peach kernels have the effects of promoting blood circulation and removing blood stasis, moistening the intestines and relieving constipation, and relieving cough and asthma. They are used for amenorrhea and dysmenorrhea, abdominal masses, lung abscess and intestinal abscess, traumatic injuries, constipation due to intestinal dryness, and cough and asthma.

[0033] Imperata cylindrica root has the following effects: cooling the blood and stopping bleeding, clearing heat and promoting diuresis. It is used for hematemesis due to blood heat, epistaxis, hematuria, thirst due to fever, cough due to lung heat, vomiting due to stomach heat, jaundice due to damp heat, edema with scanty urine, and painful urination due to heat.

[0034] This applicant, targeting common lower back and leg pain, is attempting to explore new medicinal uses for fig cakes in terms of pain relief and fatigue reduction. The applicant's research team used the Yin-Yang balance theory of Traditional Chinese Medicine to screen for a drug composition that combines desert Cistanche deserticola from Alashan, Inner Mongolia, with figs to relieve fatigue and treat bone and joint pain, specifically for lower back, shoulder, neck, and knee pain.

[0035] The applicant entered the Ejin Banner desert three times to investigate the natural growth habits of Cistanche deserticola, the herders' understanding of its medicinal value, and their practical methods of using it.

[0036] The roots of Cistanche deserticola parasitize the roots of Haloxylon ammodendron. It grows in extremely arid deserts; Ejin Banner receives only 50mm of rainfall annually. It typically grows underground for three years before emerging to flower and bear fruit. The medicinal part is the underground rhizome; its medicinal efficacy decreases after emerging, and it becomes virtually ineffective after flowering. It is best harvested before Qingming Festival (before emergence) or after October (before emergence) for optimal medicinal effect. Local elderly herders, over 50 years old, generally have aged appearances and suffer from widespread lower back and leg pain, often exhibiting unusual gait. When asked, they said that Cistanche deserticola primarily has kidney-tonifying and aphrodisiac effects. It is typically eaten stewed with mutton or soaked in alcohol with wolfberries and astragalus, but nosebleeds are a common symptom, so locals rarely consume it. Therefore, we decided to prepare a product using figs and Cistanche deserticola for the herders to try. We selected 24 individuals of different ages in Ejin Banner. Patients aged 30, 50, and 70 with pre-existing conditions who tried the product for a week reported excellent results. Mr. Hao, in particular, aged 37, who had suffered from back pain for over five years and required support to stand, experienced slow movement. After taking 40g in the morning, he was able to jog and easily climb stairs in the evening.

[0037] The local residents of Ejina used to consume Cistanche deserticola incorrectly. Cistanche deserticola is warm in nature, as is mutton, wolfberry, and astragalus. Baijiu (Chinese liquor) is also considered too hot, and the excessive use of these ingredients caused it to cause excessive heat, leading to symptoms like nosebleeds. Currently, commercially available medicinal food products contain too little of these ingredients and fail to achieve the desired kidney-tonifying and yang-boosting effects.

[0038] Research and experiments have confirmed that figs and Cistanche deserticola complement each other in terms of efficacy, making them suitable for treating certain groups of people. Cistanche deserticola is the principal herb, mainly playing a role in tonifying the kidneys and increasing blood, while figs, in addition to exerting their own medicinal effects, mainly act as a guide, directing the medicinal effects of Cistanche deserticola to the bone and joint areas. Therefore, the combination of figs and Cistanche deserticola can quickly treat, relieve, and even cure pain in the lower back, shoulders, neck, and other bone and joint areas.

[0039] The specific effects are as follows: 1. Synergistic effect to lubricate the intestines and relieve constipation: Cistanche can warm the kidneys and benefit the essence, and lubricate the intestines. Figs are rich in dietary fiber and digestive enzymes. The combination of the two can enhance intestinal peristalsis, which is especially suitable for constipation caused by weakened intestinal function in the elderly and those with weak constitution. Moreover, it is relatively mild and does not easily damage the spleen and stomach.

[0040] 2. Balancing nourishment and moisturizing: Cistanche deserticola is warm in nature and has the effect of tonifying kidney yang and replenishing essence and blood, while fig is neutral in nature and sweet in taste, and can moisturize the lungs, generate fluids, and replenish nutrition. When combined, it can nourish while avoiding excessive warming and dryness, making it suitable for people with a weak constitution and mild yin deficiency and dryness (such as soreness and weakness of the waist and knees accompanied by dry mouth).

[0041] 3. Pain treatment: It has a good therapeutic and curative effect on joint pain, neck pain, lumbar disc herniation, sciatic nerve compression pain, shoulder pain and other conditions.

[0042] For patients with blood stasis, add the blood-activating herb, peach kernel, to the combination of fig and cistanche. This promotes blood circulation, removes blood stasis, lubricates the intestines, relieves constipation, dissipates blood stasis, and clears the blood vessels.

[0043] For patients with damp-heat syndrome and those with knee pain, adding Imperata cylindrica root to the combination of Cistanche deserticola, fig, and peach kernel can clear heat and promote diuresis. At the same time, Imperata cylindrica root also has a guiding effect, which can guide the effects of other drugs to the affected area. Fig mainly guides upward, while Imperata cylindrica root mainly guides downward, so the effect of taking medicine with Imperata cylindrica root is better for patients with knee pain.

[0044] Adding peach kernel and Imperata cylindrica root to the combination of fig and Cistanche deserticola can help to counteract the potential harm of peach kernel's blood-activating properties, which could cause excessive blood heat. In turn, peach kernel can prevent excessive blood-cooling properties of Imperata cylindrica root from causing blood stagnation, thus creating a synergistic effect of activating blood without causing excessive blood heat and cooling blood without causing blood stasis.

[0045] This invention combines the above-mentioned Chinese herbal medicines according to syndrome differentiation and treatment, and rationally combines them to achieve good therapeutic and curative effects on symptoms such as knee pain, cervical pain, back pain, and shoulder pain. Example 1

[0046] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 30 grams of dried Cistanche deserticola (with skin) and 200 grams of fresh figs, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams). Example 2

[0047] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 40 grams of dried Cistanche deserticola (with skin) and 240 grams of fresh figs, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams). Example 3

[0048] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 50 grams of dried Cistanche deserticola (with skin) and 300 grams of fresh figs, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams).

[0049] Note: The dry matter content of fresh figs is (20±3) wt%. Example 4

[0050] Traditional Chinese medicine solution (or decoction) Mix the compositions described in any one of Examples 1 to 3, add water in an amount equal to the weight of the compositions, and use a cell wall breaking machine to form a slurry. Example 5

[0051] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 30 grams of peeled and wine-processed Cistanche deserticola and 20 grams of dried fig fruit, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams). Example 6

[0052] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 40 grams of peeled and wine-processed Cistanche deserticola and 40 grams of dried fig fruit, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams). Example 7

[0053] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 40 grams of peeled and wine-processed Cistanche deserticola and 50 grams of dried fig fruit, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams). Example 8

[0054] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 30 grams of peeled and wine-processed Cistanche deserticola and 20 grams of dried figs fermented for more than 4 years, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams). Example 9

[0055] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 30 grams of peeled and wine-processed Cistanche deserticola and 30 grams of dried figs fermented for more than 4 years, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams). Example 10

[0056] This embodiment provides a traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis. The composition consists of 40 grams of peeled and wine-processed Cistanche deserticola and 50 grams of dried figs fermented for more than 4 years, based on the weight of the dry matter in the raw materials (weight parts are expressed in grams). Example 11

[0057] Add 5-10 grams of peach kernels and 10-20 grams of Imperata cylindrica root to the composition described in any one of Examples 5-10. Example 12

[0058] Traditional Chinese medicine solution (or decoction) In any one of the compositions described in Examples 5 to 11, figs are dried at low temperature, vacuum-packed, frozen and fermented for more than 3 months, and then naturally fermented at room temperature for more than 3 months; Cistanche deserticola is peeled, washed, sliced, dried, soaked in rice wine, yellow wine or white wine of 18° or higher to fully absorb the wine, steamed and cooked and then dried to complete the wine-processed Cistanche deserticola; peach kernels are made by crushing wild peach kernels; Imperata cylindrica root is decocted in water; the processed raw materials are mixed with 5 to 10 times the weight of water and ground into a slurry.

[0059] The effects of the traditional Chinese medicine composition of this invention will be illustrated below through case data.

[0060] I. Case Selection Criteria: 1. Patients with pain in the lower back, lumbar spine, shoulder, shoulder joint, or cervical spine for more than 3 years, aged 30-80 years, regardless of gender; 2. Patients with leg and knee pain for more than 3 years, aged 30-80, regardless of gender.

[0061] According to the above criteria, a total of 80 subjects were included in the trial, including 40 patients with pain in the lower back, lumbar spine, shoulder, shoulder joint, and cervical spine for more than 3 years, and 40 patients with pain in the legs and knee joints for more than 3 years.

[0062] II. Dosing regimen: For the experimental cases, the traditional Chinese medicine solution of Example 4 or Example 12 was administered twice a day, i.e., once in the morning and once in the evening. For patients with leg and knee pain and patients with blood stasis in the painful area, the decoction of Example 12 with added peach kernel and Imperata cylindrica root was used for 40 consecutive days.

[0063] III. Effects of medication: This medication has a significant pain-relieving effect on patients with pain in the lower back, lumbar spine, shoulder, shoulder joints, neck, legs, and knees. Some patients experienced pain relief on the first day of taking the medication, and most people began to experience pain relief after 3 days, with improvement each day. About one-quarter of the patients experienced complete pain relief after 40 days of continuous use; no patients in the trial had no adverse effects from the medication.

[0064] Based on observations of the experimental population, the herbal solution of Example 4 showed slightly poor pain relief and was prone to causing diarrhea; the herbal solution of Example 12, in which the solution using peeled and wine-processed Cistanche deserticola and fermented figs aged for more than 4 years as raw materials showed the best pain relief effect.

[0065] Typical case: Lu XX, male, 62 years old, from Baotou, Inner Mongolia Past medical history: I first experienced neck pain in 1998, with a stiff neck and the first time I discovered I couldn't sleep flat.

[0066] I have been experiencing lower back pain for over 20 years.

[0067] I've had numbness and pain in my shoulder for over ten years. I can't scrub myself in the bath, and I can't put my arm over my shoulder.

[0068] September 1, 2024. Sudden, severe onset of lumbar disc herniation and sciatica, with muscle cramps in the lower back, thighs, and calves. The pain was excruciating, making walking impossible; no sitting, standing, or lying position was comfortable. I could only stand up and walk for about 10 minutes at a time. This lasted for two months until the pain subsided at the end of October.

[0069] Treatment: After the onset of lower back and leg pain, I first had a massage, but it didn't work. I then tried moxibustion and scraping twice. The pain subsided for a while, but then it returned. I had acupuncture for two weeks, which only provided relief for a few hours each time, and then the pain returned to its previous unbearable state. I also had electrotherapy for over 20 days, which provided some relief, but the pain returned after the treatment ended. A friend gave me a lumbar support pad, which provided some relief after about half a month, but the pain was still extremely severe, making it impossible to sleep at night.

[0070] Starting October 3rd, I used 40-50g of Alashan Cistanche deserticola (with skin, whole root), chopped it up, boiled it until soft, sliced ​​it, and took about 3-4 ounces of fresh figs from my own farm. I juiced them with water, stewed them, and drank the juice for a week. I had bowel movements 3 times a day. I felt stronger and the pain was very intense. Because I had more strength, I could tolerate some of the pain.

[0071] One week later, replace the fresh figs with 50-60g of dried figs and 40-50g of Cistanche deserticola. Mix them with water, juice them, and drink the juice all at once. Bowel movements will occur 1-2 times a day. The pain will be significantly relieved, the taste will be much better, and you will be able to sleep for a while. Continue taking it for another week.

[0072] Starting in the third week, I boiled the Cistanche deserticola in water and peeled it. I also replaced the dried figs with frozen dried figs from 2021 and fermented fig cakes. I used 40-50g of Cistanche deserticola and 50-60g of fig cakes, mixed them with water, juiced them, and stewed them. I slept well on the first day, sleeping for eight or nine hours straight. The pain was significantly relieved. I continued this for another two weeks. By the end of the month, the pain in my lower back and legs was gone, and my shoulders and cervical spine were also able to move freely without pain.

[0073] In early November, I finally had the strength to go to Beijing for a checkup. The head of Peking Union Medical College Hospital, after hearing my description of the pain, told me to prepare for surgery. I had an MRI on Monday, and when I went to see the doctor on Thursday to get the images, the head doctor said my blood vessels were fine, and my cervical and lumbar spine were also fine, only some narrowing in my cervical spine, nothing to worry about. Go home! No surgery or medication needed.

[0074] Afterwards, I found that I would still feel drowsy and aches when I was slightly tired, so I reduced the dosage to one-third of the previous amount and continued to take it. The feeling of fatigue did not reappear, and the drowsy and aches did not reappear. My hair was blacker than last year, my mind was clearer, and most importantly, my mental state was good. I had a good appetite and slept well.

[0075] Fatigue relief test: 1. The trial period was from August 24 to August 27, 2025. There were 32 participants, aged 25 to 72, including 19 males and 13 females, from 9 different provinces.

[0076] 2. Physical condition: 1 person with polio, 62 years old; 1 person with coccyx fracture, 45 years old; 15 people with frequent lower back pain; 13 people with knee pain, numbness and discomfort after walking more than 5 kilometers; 28 people with fatigue and lower back pain after traveling long distances by car for more than 5 hours; 15 people with frequent awakenings and nighttime urination.

[0077] 3. Test schedule: Day 1: Baotou City – Ejin Banner, 900 kilometers by bus, 12 hours of driving; Day 2: Ejin Banner Hotel – Badain Jaran Desert – Ejin Banner Hotel, 550 km by bus, experience digging for Cistanche deserticola in the Badain Jaran Desert, the whole activity lasts 15 hours; Day 3: Ejin Banner Hotel – Chake Port – Juyan Lake – Ejin Banner Hotel – Black City – Populus euphratica Forest – Ejin Banner Hotel. The bus journey is 400 kilometers, and more than 10,000 steps are walked during the journey. Day 4: Ejin Banner Hotel to Yinchuan City, 800 kilometers by bus, 12 hours of driving.

[0078] 4. Dosing regimen: The traditional Chinese medicine solution was administered according to Example 12, in which 26 people took 140 ml per day, 4 people took 280 ml per day, and 2 people took 420 ml per day.

[0079] 5. Experimental Results: During the 4-day trial, all participants were in high spirits and did not experience significant fatigue, whether it was long-distance driving, the experience of digging for Cistanche deserticola, or hiking. They also did not experience lower back pain when sitting in a car for a long time, which verifies that the product of this invention has a very significant fatigue-relieving effect.

Claims

1. A traditional Chinese medicine composition for treating bone and joint pain and relieving fatigue, characterized in that: The components of the traditional Chinese medicine composition comprise, in terms of weight parts of dry matter in the raw materials, 20-60 parts of figs, 20-60 parts of Cistanche, 0-10 parts of peach kernel, and 0-20 parts of Imperata cylindra. ​ 2. The anti-fatigue and bone and joint pain treating traditional Chinese medicine composition according to claim 1, characterized in that: The components of the traditional Chinese medicine composition comprise, in terms of weight parts of dry matter in the raw materials, 40-60 parts of figs and 40-60 parts of Cistanche.

3. The anti-fatigue and bone and joint pain treating traditional Chinese medicine composition according to claim 1, characterized in that: The components of the traditional Chinese medicine composition comprise, in terms of weight parts of dry matter in the raw materials, 20-60 parts of figs, 20-60 parts of Cistanche, 5-10 parts of peach kernel, and 5-20 parts of Imperata cylindra.

4. The Chinese medicinal composition for treating bone and joint pain according to claim 1, 2 or 3, characterized in that: The figs and Cistanche are fresh or dried products.

5. The anti-fatigue and bone and joint pain treating traditional Chinese medicine composition according to claim 1, 2 or 3, characterized in that: The Cistanche is prepared by soaking in wine, the figs are prepared by natural fermentation, the peach kernel is prepared by crushing, and the Imperata cylindra is prepared by decocting with water.

6. The anti-fatigue and bone and joint pain treating traditional Chinese medicine composition according to claim 4 or 5, characterized in that: The traditional Chinese medicine composition can be prepared into any one of granules, a decoction, a powder, a pill, a solution, and a capsule.

7. A method for preparing the traditional Chinese medicine composition for treating bone and joint pain according to claim 1, 2 or 3, characterized in that: The components of the traditional Chinese medicine composition are mixed to obtain the product.

8. The method for preparing the traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis according to claim 7, characterized in that: The preparation method comprises the following steps: (1) raw material processing: the figs are dried at low temperature, vacuum packaged, frozen and stored for fermentation for more than 3 months, and then naturally fermented at room temperature for more than 3 months; the Cistanche is peeled, washed, sliced, and dried, soaked in 18° or higher rice wine, yellow rice wine, or white wine to allow the Cistanche to fully absorb the wine, steamed and dried to obtain wine-soaked Cistanche; the peach kernel is crushed; and the Imperata cylindra is decocted with water; (2) the processed raw materials are mixed according to the proportions to obtain a traditional Chinese medicine preparation or beverage.

9. The method for preparing the traditional Chinese medicine composition for relieving fatigue and treating osteoarthritis according to claim 8, characterized in that: In step (1), the figs are dried at a temperature of 40-60°C; in step (1), the figs are frozen and stored for fermentation at a temperature of -18 to -20°C; in step (1), the figs are naturally fermented at room temperature at a temperature of 30-60°C, and the water content of the fermented figs is less than or equal to 12%; in step (1), the Cistanche is steamed and dried for 2-6 hours; and in step (2), the processed raw materials are mixed according to the proportions to obtain a traditional Chinese medicine beverage by passing the mixture through a colloid mill to obtain a slurry.

10. Use of the traditional Chinese medicine composition for treating fatigue and bone and joint pain according to claim 1, 2, or 3 in the preparation of a traditional Chinese medicine preparation for treating fatigue and bone and joint pain.