Liquid preparation mixing and storing device for medical drug production
By designing a liquid formulation mixing and storage device, which combines a mixing tank, a magnetic stirrer, and a temperature control component, the problem that existing equipment cannot simultaneously meet the requirements of mixing and storage has been solved. This has enabled efficient mixing and storage, reduced equipment costs and pollution risks, and improved production efficiency and drug quality.
Patent Information
- Application Number
- CN202510787990.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-12
- Publication Date
- 2025-12-05
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing liquid formulation mixing equipment only has a single mixing function and cannot meet storage requirements, resulting in the need for additional storage equipment in the production process, increasing equipment costs and operational complexity. Furthermore, the long mixing time leads to low efficiency and may affect drug quality.
Design a liquid preparation mixing and storage device, including a mixing tank, a magnetic stirrer, a controller, a sensing component, a temperature control component, a feeding component, and a discharging component. Through the cooperation of these components, the mixing, storage, and delivery of liquid preparations are realized. A dual stirrer design is adopted to ensure mixing uniformity and efficiency, and the liquid is kept in the optimal state through real-time monitoring and temperature control.
It enables efficient mixing and storage of liquid formulations, reduces equipment costs and operational complexity, avoids contamination risks, and improves production efficiency and drug quality.
Smart Images
Figure CN121060367A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of medical production equipment, in particular to a liquid preparation mixing and storage device for medical product production. BACKGROUND
[0002] In the process of medical product production, the mixing and storage of liquid preparations is a crucial link, directly related to the quality and efficacy of the drug, and its processing process needs to strictly follow GMP (Good Manufacturing Practice) to ensure sterility, non-pollution, and achieve the expected efficacy and safety. In the production process of liquid preparations, the mixed liquid preparations usually need to be transported to the storage equipment, and then transported to the next production process by the storage equipment.
[0003] In the prior art, the mixing equipment for liquid preparations only has a single mixing function, which cannot meet the storage needs of liquid preparations, resulting in the need for additional storage equipment in the production process, increasing the cost and complexity of the equipment, and the risk of contamination during drug delivery. At the same time, the existing mixing equipment often needs a long mixing time to ensure the mixing effect, which not only reduces the production efficiency of liquid preparations, but also may adversely affect the quality of the drug. SUMMARY
[0004] In view of the deficiencies of the prior art, the present application provides a liquid preparation mixing and storage device for medical product production, which solves the problem that the mixing equipment for liquid preparations only has a single mixing function, which cannot meet the storage needs of liquid preparations, resulting in the need for additional storage equipment in the production process, increasing the cost and complexity of the equipment, and the risk of contamination during drug delivery. At the same time, the existing mixing equipment often needs a long mixing time to ensure the mixing effect, which not only reduces the production efficiency of liquid preparations, but also may adversely affect the quality of the drug.
[0005] To achieve the above-mentioned purpose, the present application is realized by the following technical scheme: a liquid preparation mixing and storage device for medical product production, comprising a mixing tank, magnetic stirrers are installed on both sides of the bottom of the mixing tank, a controller is arranged on one side of the mixing tank, the liquid preparation mixing and storage device for medical product production further comprises a sensing assembly, which is arranged on the top of the mixing tank; a temperature control assembly is arranged on the outside of the mixing tank; a feeding assembly is arranged on one side of the mixing tank; a discharging assembly is arranged on the side of the mixing tank away from the feeding assembly; wherein the sensing assembly is used to monitor the storage environment of the liquid in the mixing tank in real time, the temperature control assembly is used to control the temperature of the liquid in the mixing tank, the feeding assembly is used to deliver raw materials of various liquid preparations into the mixing tank, and the discharging assembly is used to output the liquid preparations stored in the mixing tank.
[0006] Preferably, the sensing assembly comprises a first temperature sensor, the first temperature sensor being mounted on the top of the mixing tank and electrically connected to the controller; a pressure sensor being mounted on the top of the mixing tank and electrically connected to the controller; and a radar liquid level meter being mounted on the top of the mixing tank and electrically connected to the controller; wherein the storage temperature of the liquid medicine in the mixing tank, the pressure in the tank and the liquid level of the liquid medicine are measured in real time by the cooperation of the first temperature sensor, the pressure sensor and the radar liquid level meter, and the sensing signals are transmitted to the controller in real time, so as to monitor the mixing and storage environment of the liquid medicine in the mixing tank in real time.
[0007] Preferably, the temperature control assembly comprises a temperature control jacket, the temperature control jacket being fixedly connected to the outer wall of the mixing tank; a water inlet pipe being provided on the top of one side of the temperature control jacket; a drain pipe being provided on the bottom of the side of the temperature control jacket away from the water inlet pipe; a second temperature sensor being mounted on the inner wall of the temperature control jacket and electrically connected to the controller; a heat preservation structure being provided outside the temperature control jacket; and a heat conduction structure being provided on the side of the mixing tank and the temperature control jacket close to each other; wherein the temperature control jacket forms a sealed temperature control cavity outside the mixing tank, the circulating water is transported into the temperature control jacket through the water inlet pipe and the drain pipe, the water temperature in the temperature control cavity is measured in real time by the second temperature sensor, the accuracy of temperature adjustment is ensured, the heat exchange with the surrounding environment is reduced by the heat preservation structure, the temperature control effect is improved, and the heat transfer efficiency between the mixing tank and the circulating water is improved by the heat conduction structure.
[0008] Preferably, the heat preservation structure comprises a stainless steel sheet, the stainless steel sheet being provided outside the temperature control jacket; and an aerogel heat preservation layer being filled on the side of the temperature control jacket and the stainless steel sheet close to each other; wherein the heat exchange between the temperature control jacket and the surrounding environment is reduced by the cooperation of the stainless steel sheet and the aerogel heat preservation layer.
[0009] Preferably, the heat conduction structure comprises a heat conduction plate, a plurality of heat conduction plates being provided and fixedly connected to the outer wall of the mixing tank at equal intervals; and a plurality of turbulence holes being provided on the inside of the heat conduction plate at equal intervals; wherein the heat conduction efficiency between the mixing tank and the circulating water in the temperature control cavity is improved by the cooperation of the heat conduction plate and the turbulence hole.
[0010] Preferably, the feeding assembly comprises a feeding pipe fixedly connected to the top of the outer wall of the mixing tank; a vertical pipe fixedly connected to the top of the inner wall of the mixing tank and communicated with the feeding pipe; a plurality of ball-shaped nozzles equidistantly installed on the outer wall of the vertical pipe; a plurality of raw material conveying pipes communicated with the feeding pipe; a first electromagnetic valve installed on one end of the raw material conveying pipe close to the feeding pipe; and a flow meter installed on the raw material conveying pipe away from the first electromagnetic valve and electrically connected to the controller.
[0011] Preferably, the discharging assembly comprises a discharge pipe communicated with the bottom of the mixing tank; a second electromagnetic valve installed on one end of the discharge pipe close to the mixing tank; a conveying pump input end communicated with one end of the discharge pipe away from the mixing tank; an electromagnetic three-way valve input end communicated with the output end of the conveying pump and electrically connected to the controller; an output pipe communicated with one output end of the electromagnetic three-way valve; and a mass flow meter installed on the output pipe and electrically connected to the controller; wherein the discharge pipe is opened or closed by controlling the second electromagnetic valve, the liquid preparation in the mixing tank is pumped out by the conveying pump, and the liquid preparation is conveyed to the next process by the electromagnetic three-way valve and the output pipe, while the output amount of the liquid preparation is monitored in real time by the mass flow meter.
[0012] Preferably, a circulating filtration assembly is arranged on one side of the mixing tank, and the circulating filtration assembly comprises a circulating pipe communicated with one end of the electromagnetic three-way valve away from the output pipe; a filter input end communicated with one end of the circulating pipe away from the electromagnetic three-way valve and an output end communicated with the top of the mixing tank; wherein the circulating pipe and the discharge pipe are communicated by controlling the electromagnetic three-way valve, the liquid preparation is circulated by controlling the conveying pump, and the liquid preparation is filtered by the filter during the circulation.
[0013] Preferably, a cleaning and disinfecting assembly is arranged on one end of the feeding pipe away from the mixing tank, and the cleaning and disinfecting assembly comprises a third electromagnetic valve installed on one end of the feeding pipe away from the mixing tank and electrically connected to the controller; and a cleaning and disinfecting pipe communicated with one end of the third electromagnetic valve away from the feeding pipe; wherein the cleaning and disinfecting pipe is communicated with the feeding pipe by controlling the third electromagnetic valve when the mixing tank needs to be cleaned or disinfected, and cleaning liquid or disinfecting liquid is conveyed into the mixing tank.
[0014] Advantages
[0015] The application provides a liquid preparation mixing and storage device for medical drug production. The device has the following beneficial effects: the liquid preparation mixing and storage device for medical drug production cooperates the mixing tank, the magnetic stirrer, the controller, the sensing assembly, the temperature control assembly, the feeding assembly and the discharging assembly, accurately feeds multiple raw materials into the mixing tank in sequence, adopts the double stirrer design, improves the mixing uniformity and mixing efficiency of the liquid preparation, monitors the temperature, the tank pressure and the liquid level of the liquid medicine in real time, accurately adjusts and controls the temperature of the liquid medicine, ensures that the temperature of the liquid preparation is always in the best state of mixing and storage, directly feeds the liquid preparation stored in the mixing tank to the next production process by the discharging assembly, meets the process requirements of the liquid preparation mixing and storage at the same time, reduces the equipment cost and operation complexity, and avoids the pollution risk in the conveying process of the liquid preparation from the mixing equipment to the storage equipment in the traditional production process, which helps to improve the production efficiency and product quality of the liquid preparation.
[0016] Through the cooperation of the mixing tank, the controller, the feeding assembly, the discharging assembly, the circulating filtration assembly and the cleaning and disinfecting assembly, the liquid preparation is circulated during the mixing process, which can improve the mixing efficiency of the liquid preparation. At the same time, the liquid preparation is filtered during the circulation process, effectively removing impurities in the liquid preparation to ensure the quality and stability of the liquid preparation. After the mixing tank is emptied, the cleaning liquid or disinfecting liquid is conveyed from the cleaning and disinfecting pipe to the mixing tank and uniformly sprayed from the ball-shaped nozzle, which can thoroughly clean or disinfect the inside of the mixing tank, thereby ensuring the hygiene and safety of the liquid preparation production environment, which can further improve the product quality of the liquid preparation. BRIEF DESCRIPTION OF DRAWINGS
[0017] Figure 1 It is a structural schematic diagram of the application;
[0018] Figure 2 It is an appearance schematic diagram of the mixing tank, the magnetic stirrer and the temperature control jacket in the application;
[0019] Figure 3 It is an appearance sectional view of the mixing tank, the magnetic stirrer and the temperature control jacket in the application;
[0020] Figure 4 It is an appearance schematic diagram of the vertical pipe and the ball-shaped nozzle in the application;
[0021] Figure 5 It is Figure 1 a local enlarged view of area A in the application;
[0022] Figure 6 It is Figure 1 a local enlarged view of area B in the application;
[0023] Figure 7 For Figure 3 Local enlarged view of the middle C area.
[0024] In the figure: 1, mixing tank; 2, magnetic stirrer; 3, controller; 4, sensing assembly; 5, temperature control assembly; 6, feeding assembly; 7, discharging assembly; 8, circulating filtration assembly; 9, cleaning and disinfecting assembly; 41, first temperature sensor; 42, pressure sensor; 43, radar liquid level meter; 51, temperature control jacket; 52, water inlet pipe; 53, drain pipe; 54, second temperature sensor; 55, heat preservation structure; 56, heat conduction structure; 61, feeding pipe; 62, standpipe; 63, ball-shaped nozzle; 64, raw material conveying pipe; 65, first electromagnetic valve; 66, flow meter; 71, discharge pipe; 72, second electromagnetic valve; 73, conveying pump; 74, electromagnetic three-way valve; 75, output pipe; 76, mass flow meter; 81, circulating pipe; 82, filter; 91, third electromagnetic valve; 92, cleaning and disinfecting pipe; 551, stainless steel sheet; 552, aerogel heat preservation layer; 561, heat conduction plate; 562, turbulence hole. DETAILED DESCRIPTION
[0025] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.
[0026] The mixing device of the liquid preparation only has a single mixing function, which cannot meet the storage requirements of the liquid preparation, resulting in the need for additional storage devices in the production process, increasing the device cost and operation complexity, and the risk of contamination during drug delivery. At the same time, the existing mixing device often needs a long mixing time to ensure the mixing effect, which not only reduces the production efficiency of the liquid preparation, but also may have adverse effects on the quality of the drug.
[0027] Therefore, the medical liquid preparation mixing and storing device is provided, which comprises a mixing tank, a magnetic stirrer, a controller, a sensing assembly, a temperature control assembly, a feeding assembly and a discharging assembly.
[0028] By the person skilled in the art, the parts in the case are connected in sequence, and the specific connection and operation sequence should be referred to the working principle, and the detailed connection means is the known technology in the art, and the working principle and process are mainly introduced below.
[0029] By Figures 1-7 It can be known that the medical liquid preparation mixing and storing device comprises a mixing tank 1, magnetic stirrers 2 installed on both sides of the bottom of the mixing tank 1, a controller 3 arranged on one side of the mixing tank 1, a sensing assembly 4, a temperature control assembly 5, a feeding assembly 6 and a discharging assembly 7, wherein the sensing assembly 4 is arranged on the top of the mixing tank 1, the temperature control assembly 5 is arranged on the outside of the mixing tank 1, the feeding assembly 6 is arranged on one side of the mixing tank 1, and the discharging assembly 7 is arranged on the side of the mixing tank 1 away from the feeding assembly 6; the sensing assembly 4 is used for monitoring the storage environment of the liquid medicine in the mixing tank 1 in real time, the temperature control assembly 5 is used for controlling the temperature of the liquid medicine in the mixing tank 1, the feeding assembly 6 is used for feeding the raw materials of the liquid preparation into the mixing tank 1, and the discharging assembly 7 is used for discharging the liquid preparation stored in the mixing tank 1.
[0030] In the implementation process, it is particularly worth pointing out that the mixing tank 1 is used for mixing and storing liquid preparations, through the cooperation between the mixing tank 1 and the magnetic stirrer 2, the magnetic stirrer 2 is installed symmetrically on both sides of the bottom of the mixing tank 1, which improves the mixing uniformity and efficiency of the liquid preparation, reduces the time required for mixing and stirring of the liquid preparation, and fully mixes the raw materials of the liquid preparation in the larger mixing tank 1, the controller 3 is used for intelligent control of the liquid preparation mixing and storage device for the whole medical product production, through the preset program, the electrical elements of the sensing assembly 4, the temperature control assembly 5, the feeding assembly 6 and the discharging assembly 7 are automatically controlled, the automatic mixing, temperature control, raw material conveying and stable storage of the liquid preparation are realized, through the cooperation between the mixing tank 1, the magnetic stirrer 2, the controller 3, the sensing assembly 4, the temperature control assembly 5, the feeding assembly 6 and the discharging assembly 7, the multiple raw materials are conveyed into the mixing tank 1 in turn through the feeding assembly 6, and the conveying amount of each raw material is accurately controlled to ensure the accurate proportioning of the raw materials, the double stirrer design is adopted to improve the mixing uniformity and efficiency of the liquid preparation, the storage temperature, tank pressure and liquid level of the liquid medicine in the mixing tank 1 are monitored in real time through the sensing assembly 4, the temperature of the liquid medicine in the mixing tank 1 is accurately adjusted and controlled through the temperature control assembly 5, the temperature of the liquid preparation is always kept in the best state of mixing and storage, and the liquid preparation stored in the mixing tank 1 is directly conveyed to the next production process through the discharging assembly 7, so that the device meets the process requirements of liquid preparation mixing and storage at the same time, reduces the equipment cost and operation complexity, and avoids the pollution risk in the conveying process of the liquid preparation from the mixing device to the storage device in the traditional production process, improves the production efficiency and product quality of the liquid preparation;
[0031] Further, the sensing assembly 4 includes a first temperature sensor 41, a pressure sensor 42 and a radar liquid level meter 43, the first temperature sensor 41 is installed on the top of the mixing tank 1 and electrically connected to the controller 3; the pressure sensor 42 is installed on the top of the mixing tank 1 and electrically connected to the controller 3; the radar liquid level meter 43 is installed on the top of the mixing tank 1 and electrically connected to the controller 3; wherein through the cooperation of the first temperature sensor 41, the pressure sensor 42 and the radar liquid level meter 43, the storage temperature, tank pressure and liquid level of the liquid medicine in the mixing tank 1 are measured in real time, and the sensing signals are transmitted to the controller 3 in real time, and the liquid mixing and storage environment in the mixing tank 1 is monitored in real time;
[0032] In the specific implementation process, it is particularly worth pointing out that the storage temperature of the liquid medicine in the mixing tank 1, the pressure in the tank and the liquid level of the liquid medicine are measured in real time by the first temperature sensor 41, the pressure sensor 42 and the radar liquid level meter 43, and the sensing signals are transmitted to the controller 3 in real time, so that the control system can monitor the mixing and storage environment of the liquid medicine in the mixing tank 1 and the liquid level of the liquid medicine in real time, so as to timely adjust the mixing and storage conditions of the liquid medicine in the mixing tank 1, and ensure the safety and stability of the liquid preparation during mixing and storage. The specific model of the first temperature sensor 41, the pressure sensor 42 and the radar liquid level meter 43 is not limited, and it can meet the use requirement;
[0033] Further, the temperature control assembly 5 includes a temperature control jacket 51, a water inlet pipe 52, a drain pipe 53, a second temperature sensor 54, a heat preservation structure 55 and a heat conduction structure 56. The temperature control jacket 51 is fixedly connected to the outer wall of the mixing tank 1. The water inlet pipe 52 is provided on one side of the top of the temperature control jacket 51. The drain pipe 53 is provided on the bottom of the side of the temperature control jacket 51 away from the water inlet pipe 52. The second temperature sensor 54 is installed on the inner wall of the temperature control jacket 51 and is electrically connected to the controller 3. The heat preservation structure 55 is arranged outside the temperature control jacket 51. The heat conduction structure 56 is arranged on the side of the mixing tank 1 and the temperature control jacket 51 close to each other. The temperature control jacket 51 forms a sealed temperature control cavity outside the mixing tank 1. The circulating water is transported into the temperature control jacket 51 through the water inlet pipe 52 and the drain pipe 53. The water temperature in the temperature control cavity is measured in real time by the second temperature sensor 54 to ensure the accuracy of temperature adjustment. The heat exchange with the surrounding environment is reduced by the heat preservation structure 55 to improve the temperature control effect. The heat transfer efficiency between the mixing tank 1 and the circulating water is improved by the heat conduction structure 56;
[0034] In the specific implementation process, it is particularly worth pointing out that a sealed temperature control cavity is formed between the mixing tank 1 and the temperature control jacket 51. The circulating and temperature control of the liquid medium in the temperature control cavity are realized by connecting the water inlet pipe 52 and the drain pipe 53 with the external circulating water conveying pipeline and the temperature control equipment. The temperature of the liquid medium is measured by the second temperature sensor 54. The temperature of the liquid medium is adjusted in real time by the control system according to the set temperature value. At the same time, the heat loss in the temperature control process is reduced by the heat preservation structure 55 to improve the stability and efficiency of the temperature control. The heat exchange area and heat conduction efficiency between the mixing tank 1 and the circulating water in the temperature control cavity are improved by the heat conduction structure 56 to ensure that the temperature of the liquid medicine in the mixing tank 1 is always in the best state of mixing and storage. The specific model of the second temperature sensor 54 is not limited, and it can meet the use requirement;
[0035] Further, the heat preservation structure 55 comprises a stainless steel sheet 551 and an aerogel heat preservation layer 552, the stainless steel sheet 551 is arranged outside the temperature control jacket 51, and the aerogel heat preservation layer 552 is filled on the side close to the temperature control jacket 51 and the stainless steel sheet 551; wherein, through the cooperation of the stainless steel sheet 551 and the aerogel heat preservation layer 552, the heat exchange between the temperature control jacket 51 and the surrounding environment is reduced;
[0036] In the specific implementation process, it is particularly worth pointing out that the stainless steel sheet 551 is wrapped outside the temperature control jacket 51, and the aerogel heat preservation layer 552 is filled between the temperature control jacket 51 and the stainless steel sheet 551. Through the ultra-low thermal conductivity of the aerogel heat preservation layer 552, the heat transfer between the temperature control jacket 51 and the external environment is effectively isolated, the heat loss in the temperature control process is reduced, the stability and efficiency of the temperature control are improved, thereby reducing energy consumption and achieving the purpose of energy saving and emission reduction;
[0037] Further, the heat conduction structure 56 comprises heat conduction plates 561 and turbulence holes 562, the heat conduction plates 561 are arranged in multiple and fixedly connected to the outer wall of the mixing tank 1 at equal intervals, and the turbulence holes 562 are arranged in multiple and opened in the inside of the heat conduction plates 561 at equal intervals; wherein, through the cooperation of the heat conduction plates 561 and the turbulence holes 562, the heat conduction efficiency between the mixing tank 1 and the circulating water in the temperature control cavity is improved;
[0038] In the specific implementation process, it is particularly worth pointing out that by arranging the heat conduction plates 561 on the outer wall of the mixing tank 1 and utilizing the turbulence holes 562 inside the heat conduction plates 561, the heat exchange area and the heat conduction efficiency between the mixing tank 1 and the circulating water in the temperature control cavity are improved, so as to ensure that the liquid preparation in the mixing tank 1 can uniformly and quickly reach the required temperature, thereby meeting the requirements of drug production and storage;
[0039] Further, the feeding assembly 6 comprises a feeding pipe 61, a vertical pipe 62, ball-shaped nozzles 63, raw material conveying pipes 64, a first electromagnetic valve 65 and a flow meter 66, the feeding pipe 61 is fixedly connected to the top of the outer wall of the mixing tank 1, the vertical pipe 62 is fixedly connected to the top of the inner wall of the mixing tank 1 and communicated with the feeding pipe 61, the ball-shaped nozzles 63 are arranged in multiple and installed on the outer wall of the vertical pipe 62 at equal intervals, the raw material conveying pipes 64 are arranged in multiple and communicated with the feeding pipe 61, the first electromagnetic valve 65 is installed on one end of the raw material conveying pipe 64 close to the feeding pipe 61, and the flow meter 66 is installed on one side of the raw material conveying pipe 64 away from the feeding pipe 61 and electrically connected to the controller 3; wherein, the raw material conveying pipes 64 convey raw materials of multiple liquid preparations to the feeding pipe 61, the flow meter 66 monitors the raw material conveying amount, controls the opening and closing states of the first electromagnetic valve 65, adjusts the conveying amount of different raw materials, the feeding pipe 61 conveys the raw materials to the inside of the mixing tank 1, and the vertical pipe 62 and the ball-shaped nozzles 63 uniformly spray the raw materials to the inside of the mixing tank 1.
[0040] In the specific implementation process, it is particularly worth pointing out that the feed pipe 61 transports the raw materials of the liquid preparation into the mixing tank 1, and through the vertical pipe 62 and the ball nozzle 63, the raw materials can be uniformly sprayed in the inside of the mixing tank 1 to be dispersed in the form of smaller droplets, increase the contact area of the raw materials with the existing liquid medicine in the mixing tank 1, and improve the mixing uniformity and mixing efficiency of the liquid preparation. The plurality of raw material conveying pipes 64 are connected with the conveying pipelines of different liquid preparation raw materials. The conveying amount of each raw material is input through the controller 3. The control system automatically controls the corresponding first electromagnetic valve 65 according to the real-time monitoring data of the flow meter 66, so that the raw materials of the liquid preparation are transported into the inside of the mixing tank 1 in turn, and the conveying amount of each raw material conveying pipe 64 is accurately controlled to ensure the accurate proportioning of each raw material, thereby meeting the strict requirements of medical product production. The specific models of the first electromagnetic valve 65 and the flow meter 66 are not limited, and they can meet the use requirements;
[0041] Further, the discharge assembly 7 includes a discharge pipe 71, a second electromagnetic valve 72, a conveying pump 73, an electromagnetic three-way valve 74, an output pipe 75, and a mass flow meter 76. The discharge pipe 71 is communicated with the bottom of the mixing tank 1. The second electromagnetic valve 72 is installed at one end of the discharge pipe 71 close to the mixing tank 1. The input end of the conveying pump 73 is communicated with the other end of the discharge pipe 71 away from the mixing tank 1. The input end of the electromagnetic three-way valve 74 is communicated with the output end of the conveying pump 73, and the electromagnetic three-way valve 74 is electrically connected to the controller 3. The output pipe 75 is communicated with one output end of the electromagnetic three-way valve 74. The mass flow meter 76 is installed on the output pipe 75 and is electrically connected to the controller 3. By controlling the second electromagnetic valve 72, the discharge pipe 71 is opened or closed. The liquid preparation in the mixing tank 1 is pumped out through the conveying pump 73, and the liquid preparation is conveyed to the next process through the electromagnetic three-way valve 74 and the output pipe 75. At the same time, the amount of the output liquid preparation is monitored in real time through the mass flow meter 76.
[0042] In the specific implementation process, it is particularly worth pointing out that when it is necessary to discharge the liquid preparation, the second electromagnetic valve 72, the conveying pump 73, and the electromagnetic three-way valve 74 are controlled to pump out the liquid preparation in the mixing tank 1 through the conveying pump 73, convey the liquid preparation to the next process through the output pipe 75, and monitor the amount of the conveyed liquid preparation in real time through the mass flow meter 76 during the conveying process, and transmit the monitoring signals to the control system in real time to ensure the accurate output of the liquid preparation. In addition, it is convenient to count and manage the conveying amount and the remaining amount of the liquid preparation. The specific models of the second electromagnetic valve 72, the conveying pump 73, the electromagnetic three-way valve 74, and the mass flow meter 76 are not limited, and they can meet the use requirements;
[0043] Further, one side of the mixing tank 1 is provided with a circulating filtering assembly 8, which comprises a circulating pipe 81 and a filter 82. The circulating pipe 81 is communicated to the end of the electromagnetic three-way valve 74 away from the output pipe 75. The input end of the filter 82 is communicated to the end of the circulating pipe 81 away from the electromagnetic three-way valve 74, and the output end is communicated to the top of the mixing tank 1. Through the control of the electromagnetic three-way valve 74, the circulating pipe 81 and the discharge pipe 71 are communicated, and the delivery pump 73 is controlled to circulate the liquid preparation. During the circulation, the liquid preparation is filtered by the filter 82.
[0044] In the specific implementation process, it is particularly worth pointing out that when the liquid preparation is mixed, the second electromagnetic valve 72 and the electromagnetic three-way valve 74 are controlled to connect the circulating pipe 81 and the discharge pipe 71, and disconnect the output pipe 75 and the discharge pipe 71. The liquid preparation in the mixing tank 1 is delivered by the discharge pipe 71 and the circulating pipe 81 to the filter 82 for filtering, and then delivered back to the mixing tank 1 after the filtering is completed, so as to realize the circulation of the liquid preparation, improve the mixing efficiency of the liquid preparation, and effectively remove the impurities in the liquid preparation during the circulation, thereby ensuring the quality and stability of the liquid preparation.
[0045] Further, the end of the feeding pipe 61 away from the mixing tank 1 is provided with a cleaning and disinfecting assembly 9, which comprises a third electromagnetic valve 91 and a cleaning and disinfecting pipe 92. The third electromagnetic valve 91 is installed at the end of the feeding pipe 61 away from the mixing tank 1 and is electrically connected to the controller 3. The cleaning and disinfecting pipe 92 is communicated to the end of the third electromagnetic valve 91 away from the feeding pipe 61. Through the cooperation of the third electromagnetic valve 91 and the cleaning and disinfecting pipe 92, when the mixing tank 1 needs to be cleaned or disinfected, the third electromagnetic valve 91 is controlled to connect the cleaning and disinfecting pipe 92 and the feeding pipe 61, so as to deliver cleaning liquid or disinfecting liquid into the mixing tank 1.
[0046] In the specific implementation process, it is particularly worth pointing out that when the mixing tank 1 needs to be cleaned or disinfected, the third electromagnetic valve 91 is controlled and the first electromagnetic valve 65 is closed, so as to connect the cleaning and disinfecting pipe 92 and the feeding pipe 61. The cleaning liquid or disinfecting liquid is delivered into the mixing tank 1 by the water pump through the cleaning and disinfecting pipe 92 and the feeding pipe 61, and is uniformly sprayed by the ball-shaped nozzle 63, so as to comprehensively clean or disinfect the inside of the mixing tank 1, thereby ensuring the hygiene and safety of the liquid preparation production environment. The specific model of the third electromagnetic valve 91 is not limited, as long as it meets the use requirements.
[0047] Specifically, in the use of the liquid preparation mixing and storage device for medical drugs, the delivery pipelines of each raw material of the liquid preparation are connected with the raw material delivery pipeline 64, the raw material delivery amount, the stirring time, and the temperature and pressure parameters of mixing and storage are set by the controller 3, the circulating medium is continuously delivered into the temperature control cavity between the mixing tank 1 and the temperature control jacket 51 according to the set temperature condition, after the temperature required for the mixing of the liquid preparation is reached, each raw material is delivered into the inside of the mixing tank 1 according to the set parameters in turn and is uniformly sprayed by the spherical nozzle 63, at the same time, the two magnetic stirrers 2 are driven to continuously stir and mix the raw materials in the mixing tank 1, in the stirring and mixing process, the delivery pump 73 continuously delivers the liquid preparation at the bottom of the mixing tank 1 to the circulating pipeline 81 for circulation and filtration in the circulation process, after the time required for the mixing of the liquid preparation is reached, the stirring of the magnetic stirrers 2 is stopped and each valve is closed, so that the liquid preparation is stably stored in the mixing tank 1, and the temperature and pressure data in the mixing tank 1 are monitored in real time by the control system, so as to ensure that the mixing tank 1 is always in the best storage condition.
[0048] While embodiments of the application have been shown and described, it is to be understood that the embodiments described are merely divergences, modifications, replacements and variations of the embodiments, and the scope of the application is defined by the appended claims and their equivalents.
Claims
1. A liquid preparation mixing and storage device for medical drug production, comprising a mixing tank (1), characterized in that: The bottom of the mixing storage tank (1) is provided with a magnetic stirrer (2) on both sides, and one side of the mixing storage tank (1) is provided with a controller (3), and the liquid preparation mixing and storage device for medical product production further comprises: a sensing assembly (4) arranged on the top of the mixing storage tank (1); a temperature control assembly (5) arranged on the outside of the mixing storage tank (1); a feeding assembly (6) arranged on one side of the mixing storage tank (1); a discharging assembly (7) arranged on the side of the mixing storage tank (1) away from the feeding assembly (6); wherein the storage environment of the liquid medicine in the mixing storage tank (1) is monitored in real time by the sensing assembly (4), the temperature of the liquid medicine in the mixing storage tank (1) is controlled by the temperature control assembly (5), the raw materials of various liquid preparations are transported into the mixing storage tank (1) by the feeding assembly (6), and the liquid preparation stored in the mixing storage tank (1) is output by the discharging assembly (7).
2. The medical liquid preparation mixing and storing device according to claim 1, wherein: The sensing assembly (4) comprises: a first temperature sensor (41) mounted on the top of the mixing storage tank (1) and electrically connected to the controller (3); a pressure sensor (42) mounted on the top of the mixing storage tank (1) and electrically connected to the controller (3); a radar liquid level meter (43) mounted on the top of the mixing storage tank (1) and electrically connected to the controller (3); wherein the storage temperature, pressure and liquid level of the liquid medicine in the mixing storage tank (1) are measured in real time by the cooperation of the first temperature sensor (41), the pressure sensor (42) and the radar liquid level meter (43), and the sensing signals are transmitted to the controller (3) in real time, so as to monitor the mixing and storage environment of the liquid medicine in the mixing storage tank (1) in real time.
3. The medical liquid preparation mixing and storing device according to claim 2, wherein: The temperature control assembly (5) comprises: a temperature control jacket (51) fixedly connected to the outer wall of the mixing storage tank (1); a water inlet pipe (52) arranged on the top of one side of the temperature control jacket (51); a drain pipe (53) arranged on the bottom of the side of the temperature control jacket (51) away from the water inlet pipe (52); a second temperature sensor (54) mounted on the inner wall of the temperature control jacket (51) and electrically connected to the controller (3); a heat preservation structure (55) arranged outside the temperature control jacket (51); a heat conduction structure (56) arranged on the side of the mixing storage tank (1) and the temperature control jacket (51) close to each other; wherein the temperature control jacket (51) forms a sealed temperature control cavity outside the mixing storage tank (1), the circulating water is transported into the temperature control jacket (51) through the water inlet pipe (52) and the drain pipe (53), the water temperature in the temperature control cavity is measured in real time by the second temperature sensor (54), the accuracy of temperature adjustment is ensured, the heat exchange with the surrounding environment is reduced by the heat preservation structure (55), the temperature control effect is improved, and the heat transfer efficiency between the mixing storage tank (1) and the circulating water is improved by the heat conduction structure (56).
4. The medical liquid preparation mixing and storing device according to claim 3, wherein: The heat preservation structure (55) comprises: a stainless steel sheet (551) arranged outside the temperature control jacket (51); an aerogel heat preservation layer (552) filled on the side of the temperature control jacket (51) and the stainless steel sheet (551) close to each other; The heat exchange between the temperature control jacket (51) and the surrounding environment is reduced through the cooperation of the stainless steel sheet (551) and the aerogel thermal insulation layer (552).
5. The medical liquid preparation mixing and storing device according to claim 4, wherein: The heat conduction structure (56) comprises: A plurality of heat conduction plates (561) are fixedly connected to the outer wall of the mixing storage tank (1) at equal intervals; A plurality of turbulence holes (562) are arranged in the interior of the heat conduction plate (561) at equal intervals; The heat conduction efficiency between the mixing storage tank (1) and the circulating water in the temperature control cavity is improved through the cooperation of the heat conduction plate (561) and the turbulence hole (562).
6. The medical liquid preparation mixing and storing device according to claim 5, wherein: The feeding assembly (6) comprises: A feeding pipe (61) is fixedly connected to the top of the outer wall of the mixing storage tank (1); A vertical pipe (62) is fixedly connected to the top of the inner wall of the mixing storage tank (1) and is communicated with the feeding pipe (61); A plurality of ball-shaped nozzles (63) are installed on the outer wall of the vertical pipe (62) at equal intervals; A plurality of raw material conveying pipes (64) are communicated with the feeding pipe (61); A first electromagnetic valve (65) is installed on one end of the raw material conveying pipe (64) close to the feeding pipe (61); A flow meter (66) is installed on one side of the raw material conveying pipe (64) away from the first electromagnetic valve (65) and is electrically connected to the controller (3); The raw material conveying pipe (64) conveys the raw materials of multiple liquid preparations to the feeding pipe (61), the flow meter (66) monitors the raw material conveying amount, controls the opening and closing states of the first electromagnetic valve (65), adjusts the conveying amount of different raw materials, the feeding pipe (61) conveys the raw materials into the mixing storage tank (1), and the vertical pipe (62) and the ball-shaped nozzle (63) uniformly spray the raw materials into the interior of the mixing storage tank (1).
7. The medical liquid preparation mixing and storage device according to claim 6, wherein: The discharging assembly (7) comprises: A discharge pipe (71) is communicated with the bottom of the mixing storage tank (1); A second electromagnetic valve (72) is installed on one end of the discharge pipe (71) close to the mixing storage tank (1); A conveying pump (73) is input communicated with one end of the discharge pipe (71) away from the mixing storage tank (1); An electromagnetic three-way valve (74) is input communicated with the output end of the conveying pump (73) and is electrically connected to the controller (3); An output pipe (75) is communicated with one output end of the electromagnetic three-way valve (74); A mass flow meter (76) is installed on the output pipe (75) and is electrically connected to the controller (3); The second electromagnetic valve (72) is controlled to open or close the discharge pipe (71), the conveying pump (73) is used to pump out the liquid preparation in the mixing storage tank (1), the electromagnetic three-way valve (74) and the output pipe (75) are used to convey the liquid preparation to the next process, and the mass flow meter (76) is used to monitor the output liquid preparation amount in real time.
8. The medical liquid preparation mixing and storing device according to claim 7, wherein: A circulating filtration assembly (8) is arranged on one side of the mixing storage tank (1), and the circulating filtration assembly (8) comprises: A circulating pipe (81) is communicated with one end of the electromagnetic three-way valve (74) away from the output pipe (75); A filter (82) is connected to the end of the circulation pipe (81) away from the electromagnetic three-way valve (74) and to the top of the mixing tank (1); Wherein, by controlling the electromagnetic three-way valve (74), the circulation pipe (81) and the discharge pipe (71) are communicated, and the delivery pump (73) is controlled to circulate the liquid preparation, and in the circulation process, the liquid preparation is filtered by the filter (82).
9. The medical liquid preparation mixing and storage device according to claim 8, wherein: The end of the feed pipe (61) away from the mixing tank (1) is provided with a cleaning and disinfecting assembly (9), which comprises: A third electromagnetic valve (91) is installed at the end of the feed pipe (61) away from the mixing tank (1) and is electrically connected to the controller (3); A cleaning and disinfecting pipe (92) is connected to the end of the third electromagnetic valve (91) away from the feed pipe (61); Wherein, by cooperation of the third electromagnetic valve (91) and the cleaning and disinfecting pipe (92), when it is necessary to clean or disinfect the mixing tank (1), the third electromagnetic valve (91) is controlled to make the cleaning and disinfecting pipe (92) communicate with the feed pipe (61), and the cleaning liquid or disinfecting liquid is delivered into the mixing tank (1).