An implantable breathing assist device

Abstract

The application discloses an implantable breathing assisting device, which comprises fixed magnetic sheets and moving magnetic sheets matched with each other, and an auxiliary air bag, when in an expiration phase, the fixed magnetic sheets and the moving magnetic sheets repel each other, the lung body contracts to exhale gas, and sterile gas in the auxiliary air bag is retracted to form an air bag between the lung body and a thoracic cavity; when in an inspiration phase, the fixed magnetic sheets and the moving magnetic sheets attract each other, the lung body expands to inhale gas, and the sterile gas in the auxiliary air bag gathers to form an air bubble at a lung tip of the lung body, the application can obviously improve lung ventilation and lung gas exchange functions, improve lung breathing, and can be used for treatment of most current lung diseases causing respiratory insufficiency, especially chronic obstructive pulmonary diseases and respiratory related infectious diseases, and even patients needing long-term use of a breathing machine to assist breathing, and is also suitable for patients with respiratory insufficiency caused by other diseases.

Description

Technical Field

[0001] This invention relates to the field of assisted breathing technology, and more particularly to an implantable respiratory assist device. Background Technology

[0002] Respiration is the process of gas exchange between the body and the external environment, including external respiration, gas transport, and internal respiration. External respiration mainly refers to pulmonary ventilation and pulmonary gas exchange. When pulmonary ventilation and pulmonary gas exchange are abnormal, it can cause common lung diseases in our daily lives: chronic obstructive pulmonary disease (COPD) (COPD emphysema, chronic bronchitis, asthma, etc.), respiratory-related infectious diseases, bronchiectasis, sleep apnea syndrome, acute respiratory distress syndrome, respiratory failure, etc. Among them, COPD has become a major cause of morbidity and mortality worldwide. It is characterized by airflow obstruction due to chronic bronchitis or emphysema, and impaired pulmonary ventilation and pulmonary gas exchange. Respiratory-related infectious diseases are often pandemic-like infectious diseases that cause serious public health events and have serious harms such as high transmissibility, high disability and mortality rates.

[0003] The incidence, prevalence, and health-related costs of chronic obstructive pulmonary disease (COPD) are all rising, as is the mortality rate from COPD. Furthermore, COPD is a progressive disease and currently incurable. Current treatments for COPD include prevention of further respiratory damage, medication, and surgery. Prevention of further respiratory damage primarily relies on a healthy lifestyle, with smoking cessation considered one of the most important interventions. For those experiencing impaired daily activities or quality of life, pulmonary rehabilitation programs may be necessary, including respiratory muscle training and retraining, and long-term oxygen therapy. Medication includes bronchodilators, steroids, and antibiotics. However, medication cannot reverse the progression of COPD, and respiratory-related infectious diseases, especially severe cases, often lead to respiratory failure in later stages, requiring prolonged mechanical ventilation.

[0004] In the compensated stage of chronic obstructive pulmonary disease (COPD), excessive expansion of lung tissue leads to pathological enlargement of the thoracic cavity, resulting in a barrel chest. In the decompensated stage, the barrel chest can no longer expand to provide more volume for the expanded lung tissue. Simultaneously, due to weakened elastic recoil of the lung tissue, the volume of inhalation and exhalation decreases, i.e., tidal volume (the amount of air inhaled or exhaled with each breath) and minute ventilation decrease, leading to dyspnea. Therefore, surgical treatment options are available for this condition. Lung transplantation is a surgical treatment option for the end-stage of COPD; however, due to the limited supply of donor organs, lung transplantation is only available to a small percentage of patients. Another treatment method is lung volume reduction surgery, which works by reducing the volume of the lungs to increase their retraction space within the thoracic cavity. Specifically, it involves reducing or removing the most affected part of the lung through interventional or surgical resection. This indicates that patients experience increased forced expiratory volume, reduced total lung volume, and significant improvements in lung function, dyspnea, and quality of life. However, lung volume reduction surgery may lead to complications such as insufficient ventilation, pulmonary edema, pulmonary hypertension, respiratory failure, and infection. Furthermore, over time, the remaining lung tissue may continue to expand and fill the entire thoracic cavity, returning to the pre-operative state and causing respiratory failure symptoms. Currently, there are solutions such as intelligent respiratory support vests, but their effectiveness is limited. Patients with respiratory infectious diseases often present with a large amount of viscous secretions in the alveoli and airways that they cannot cough up, leading to respiratory failure and requiring mechanical ventilation, postural drainage, and suctioning. However, the treatment effect is limited for severely ill patients. Therefore, there is a need for a method that can effectively assist lung respiration and improve patients' respiratory function without removing or transplanting lung tissue. Summary of the Invention

[0005] In order to overcome the shortcomings of the prior art, the technical problem to be solved by the present invention is to propose an implantable respiratory assist device, which is surgically implanted into the body to effectively improve lung function, namely, to assist the elastic recoil of the lungs, improve ventilation, and increase oxygen partial pressure and blood pressure saturation.

[0006] To achieve this objective, the present invention adopts the following technical solution:

[0007] This invention provides an implantable respiratory assist device, comprising an assistive cuff. A plurality of cooperating fixed and movable magnetic plates are fixedly mounted on both sides of the assistive cuff. The assistive cuff is disposed between the lung body and the thoracic cage. The fixed magnetic plates are fixed to the thoracic cage, and the movable magnetic plates are fixed to the lung body. One side of the assistive cuff is fixed to the surface of the thoracic cage, and the other side is fixed to the surface of the lung body. The assistive cuff is also filled with sterile gas. Preferably, it further includes a respiratory trigger for sensing respiratory status and a parameter controller for adjusting the respiratory mode. The respiratory trigger is fixedly mounted on... The system includes a fixed magnetic sheet and a movable magnetic sheet, both fixed and movable, with a converter within each. The fixed magnetic sheet and movable magnetic sheet are designed to switch between repulsive and attractive states. A battery assembly is also included, fixed to the surface of the thoracic cavity to power the various components. The auxiliary airbag has several external connection points evenly distributed between it and the thoracic cavity surface to secure it. Similarly, several internal connection points are evenly distributed between the auxiliary airbag and the surface of the lung body to secure it.

[0008] During the expiratory phase, the fixed magnetic sheet and the movable magnetic sheet repel each other, the lung body contracts and exhales gas, and the sterile gas in the auxiliary air bag retracts to form an air bag between the lung body and the thoracic cavity.

[0009] During the inspiratory phase, the fixed magnetic sheet and the movable magnetic sheet attract each other, the lung body expands and inhales gas, and the sterile gas in the auxiliary air sac gathers at the apex of the lung body to form a bubble.

[0010] To derive a more regular and universal relationship, the parameter controller is used to further record the repulsive distance L between the fixed and moving magnetic sheets, and the respiratory rate X of the lung body per minute, specifically including:

[0011] The repulsive distance L between the fixed and moving magnetic sheets and the respiratory rate X of the lung body satisfy the following:

[0012]

[0013] Where Y is the ventilation per minute of the lung body during respiration, that is, the ventilation per minute of the lung body when the repulsive distance between the fixed magnetic sheet and the moving magnetic sheet is L, and the respiratory rate of the lung body is X per minute, and a, b, and c are fitting parameters.

[0014] The beneficial effects of this invention are as follows:

[0015] (1) This invention can significantly improve lung ventilation and lung gas exchange function in patients with emphysema (lung body expansion and poor recoil ability) and lung-related infectious diseases (such as alveoli unable to perform normal gas exchange), improve lung respiration, and can be used for the treatment of most lung diseases, especially chronic obstructive pulmonary disease and respiratory-related infectious diseases. It is also applicable to other respiratory diseases caused by external respiratory function.

[0016] (2) When inhalation is triggered, the fixed magnetic sheet and the moving magnetic sheet generate magnetic fields that attract each other, causing the fixed magnetic sheet and the moving magnetic sheet to move closer to each other to assist the expansion of lung tissue, increase lung inhalation volume, force inhalation speed and tidal volume, and at the same time squeeze the gas between the two into the tension bubble at the top, compressing the lung apex.

[0017] When exhalation is triggered, the fixed and movable magnetic sheets generate magnetic fields with repulsion between their like poles, causing them to separate and move away to assist in the contraction of lung tissue. At this time, the tension bubbles collapse, and the sterile gas in the tension assist cuff flows into the space between the fixed and movable magnetic sheets (i.e., forming an air bag).

[0018] (3) During exhalation, the fixed magnetic sheet and the movable magnetic sheet repel each other, and the gas in the air bag flows from the apex of the lung to the space between the lung tissue and the thoracic cage to form an air bag, increasing the exhalation volume. During inhalation, the fixed magnetic sheet and the movable magnetic sheet attract each other, and the gas in the air bag flows from the space between the lung tissue and the thoracic cage to the apex of the lung to form an air bubble, increasing the inhalation volume. In this process, the compressibility and expansion of the auxiliary air bag are achieved, so that the pressure balance between the surface of the thoracic cage and the surface of the lung body is maintained during breathing. That is, the fixed magnetic sheet and the movable magnetic sheet can repel and attract each other normally, increasing the tidal volume. The tidal volume changes according to the change of the magnetic force. This is repeated to achieve assisted breathing: it can significantly enhance elastic recoil, improve ventilation, and increase the rate of forced breathing. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of an implantable respiratory assist device provided in a specific embodiment of the present invention, with the lung body in the inspiratory phase;

[0020] Figure 2 This is a schematic diagram of an implantable respiratory assist device provided in a specific embodiment of the present invention, with the lung body in the expiratory phase.

[0021] In the picture:

[0022] 1. Fixed magnetic sheet; 2. Moving magnetic sheet; 3. Thoracic cavity; 4. Lung body; 5. Assistive air bag; 51. Air bag; 52. Air bubble; 6. Breathing trigger; 7. Parameter controller; 8. Battery assembly; 31. External contact; 41. Internal contact. Detailed Implementation

[0023] The technical solution of the present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0024] In order to effectively assist lung respiration and improve the patient's respiratory function without removing and transplanting lung tissue, the present invention provides an implantable respiratory assist device.

[0025] Example 1: As shown in the figure, the present invention provides an implantable respiratory assist device, including an assistive airbag 5. Several fixed magnetic plates 1 and movable magnetic plates 2 are fixedly mounted on both sides of the assistive airbag 5. The assistive airbag 5 is positioned between the lung body 4 and the thoracic cage 3. The fixed magnetic plates 1 are fixed to the thoracic cage 3, and the movable magnetic plates 2 are fixed to the lung body 4. One side of the assistive airbag 5 is fixed to the surface of the thoracic cage 3, and the other side is fixed to the surface of the lung body 4. Thus, the assistive airbag 5, the fixed magnetic plates 1, and the movable magnetic plates 2 form a whole. The assistive airbag 5 is also filled with sterile gas. Furthermore, it includes a respiratory trigger 6 for sensing the respiratory state and a parameter controller 7 for adjusting the respiratory mode. The respiratory trigger 6 and... The parameter controller 7 is fixed to the surface of the thoracic cavity 3; furthermore, it also includes a battery assembly 8, which is fixed to the surface of the thoracic cavity 3 to supply power to each component; during the implantation of the assisted breathing device in this case, the patient (obstructive lung disease) is under general anesthesia, and a double-lumen endotracheal intubation is performed. During the operation, ventilation of the unilateral lung requiring the implantation of the assisted breathing device is reduced. The assisted breathing device is implanted into the thoracic cavity through a minimally invasive small incision in that side of the intercostal space, and the movable magnetic sheet 2 and the fixed magnetic sheet 1 are fixed in their respective positions. At the same time, the respiratory trigger 6 and the parameter controller 7 are fixed to the thoracic cavity. Finally, the battery assembly 8 is fixed subcutaneously or externally. Similarly, the assisted breathing device can be implanted into the thoracic cavity on the other side.To restore lung ventilation, the parameter controller 7 is adjusted to a suitable tidal volume to meet normal living needs. Therefore, during implantation, a biocompatible membrane is used to wrap the implant, which facilitates fixation during surgery and ensures post-implantation safety. Based on this, the principle of this case mainly utilizes the electromagnetic principle of like poles repelling and unlike poles attracting. A fixed magnetic sheet 1 is fixed to the inner wall of the thoracic cavity 3, and a movable magnetic sheet 2 is fixed to the surface of the lung body 4. A battery assembly 8, a respiratory trigger 6, and a parameter controller 7 are fixed to the thoracic cavity 3 to cooperate with the fixed magnetic sheet 1 and the movable magnetic sheet 2. Under the control of the parameter controller 7, in order for the fixed magnetic sheet 1 and the movable magnetic sheet 2 to periodically repel and attract each other, the magnetic poles of the fixed magnetic sheet 1 and the movable magnetic sheet 2 need to be periodically changed. This allows the fixed magnetic sheet 1 and the movable magnetic sheet 2 to assist the elastic recoil of the lung body 4, thereby assisting the breathing of the lung body 4. This requires the fixed magnetic sheet 1 and the movable magnetic sheet 2 to... A converter is also provided to switch the repulsive or attractive states of the fixed magnetic plate 1 and the movable magnetic plate 2; that is, when the fixed magnetic plate 1 and the movable magnetic plate 2 are like poles and repel each other, they compress the lung body 4 and assist exhalation; when the fixed magnetic plate 1 and the movable magnetic plate 2 are opposite poles and attract each other, they pull the lung body 4 and assist inhalation, thereby achieving the purpose of assisted breathing. In order to achieve this purpose, it is also necessary to overcome the internal pressure, otherwise the lung body 4 will not be able to be pulled back by the fixed magnetic plate 1 and the movable magnetic plate 2 due to the imbalance of internal air pressure. Therefore, an auxiliary airbag 5 is also included. The auxiliary airbag 5 is set between the lung body 4 and the thoracic cage 3. One side of the auxiliary airbag 5 is fixed to the surface of the thoracic cage 3, and the other side is fixed to the surface of the lung body 4. Specifically, a number of external connection points 31 are evenly arranged between the auxiliary airbag 5 and the surface of the thoracic cage 3 to fix the auxiliary airbag 5 to the surface of the thoracic cage 3, and a number of internal connection points 41 are evenly arranged between the auxiliary airbag 5 and the surface of the lung body 4 to fix the auxiliary airbag 5 to the surface of the lung body 4.

[0026] It should be further explained that the fixed magnetic sheet 1 and the movable magnetic sheet 2 are electromagnetic sheets. Through a built-in converter, the fixed magnetic sheet 1 and the movable magnetic sheet 2 can dynamically change the direction of the current, thereby changing the direction of the magnetic poles of the two magnetic sheets. This controls whether the magnetic force between the two magnetic sheets is repulsive (like poles) or attractive (opposite poles). Specifically, during the inspiratory phase, the converter sets the magnetic poles of the fixed magnetic sheet 1 and the movable magnetic sheet 2 to opposite poles (NS), generating an attractive force. The movable magnetic sheet 2 moves closer to the fixed magnetic sheet 1, assisting the expansion of the lung body 4 and completing the inhalation. During the expiratory phase, the converter switches the magnetic poles of the two magnetic sheets to like poles (NN). (or SS), generating a repulsive force, moving the magnetic plate 2 and the fixed magnetic plate 1 away from each other, assisting the lung body 4 to contract and complete exhalation; the respiratory trigger 6, fixed in the thoracic cavity 3 or on the surface of the lung body 4, transmits the signal to the converter and parameter controller 7 built into the two magnetic plates after sensing the initial signal of each spontaneous inhalation or exhalation. The converter in the magnetic plate adjusts the direction of the current to change the direction of the magnetic force, so as to achieve repulsion or attraction between the two magnetic plates. At the same time, the parameter controller 7 can adjust the output current to change the magnitude of the magnetic force, thereby achieving effective minute ventilation and tidal volume; therefore, the converter in the magnetic plate receives the signal changes of spontaneous breathing sensed by the respiratory trigger 6, so as to achieve periodic repulsion and attraction between the two magnetic plates. Furthermore, since the respiratory trigger 6 is fixed within the thoracic cavity 3 or on the surface of the lung body 4, during exhalation or inhalation, the respiratory trigger 6, which has a built-in tension sensing element, senses changes in the surface tension of the thoracic cavity 3 or lung body 4 during respiration and generates corresponding surface tension parameter change transmission signals. Specifically, after sensing the initial signal of each spontaneous inhalation or exhalation, the respiratory trigger 6 transmits the signal to the converter and parameter controller 7 built into the magnetic sheet. The converter in the magnetic sheet adjusts the direction of the current and the change in the direction of the magnetic force to achieve repulsion or attraction between the two magnetic sheets. At the same time, the parameter controller 7 can adjust the output current to change the magnitude of the magnetic force, thereby achieving effective minute ventilation and tidal volume. In this way, the respiratory trigger 6, by sensing spontaneous breathing movements, achieves precise synchronization between the periodic respiratory assistance actions (i.e., repulsion or attraction) of the two magnetic sheets and the patient's spontaneous breathing.

[0027] Preferably, the parameter controller 7 has functions such as adjusting the breathing mode, frequency, magnetic force, and sensing the movement distance of the moving magnetic sheet. Specifically, the breathing mode is generally divided into spontaneous breathing trigger mode and fixed breathing mode. For patients with spontaneous breathing, the spontaneous breathing trigger mode is used, which provides a better experience for the patient and avoids respiratory aggression. For patients under anesthesia or sedation or without spontaneous breathing, the fixed breathing mode can be used. The distance L between the two repulsive magnetic sheets and the breathing frequency X are set by the patient's normal minute ventilation Y to achieve assisted breathing. Before implantation, the calibration curve of the "LXY correspondence" of the respiratory assist device is measured and stored in the parameter controller 7 (each patient's situation is different, so it needs to be simulated and measured in advance before the parameter controller 7 is implanted, and then stored in the parameter controller 7). Based on changes in the patient's age, weight, height, and other factors, the required improvement in minute ventilation (with tidal volume and respiratory rate X being known constants) is set to ensure the patient remains within a safe adjustment range. The parameter controller 7 can then directly query or calculate the required magnetic repulsion distance L for the patient, and adjust the current to change the magnetic force, thus achieving the set distance L. Therefore, after the respiratory assist device is implanted, based on the actual measured change in minute ventilation Y, the magnetic repulsion distance L1 after implantation can be directly queried or calculated using the calibration curve of the "LXY correspondence" stored in the parameter controller 7. If the distance L1 is less than the set distance L, the output current is increased to enhance the repulsion magnetic force and achieve the set distance L; conversely, if the distance L1 is greater than the set distance L, the output current is reduced to decrease the repulsion magnetic force and achieve the set distance L.

[0028] In summary, during the expiratory phase, the fixed magnetic plate 1 and the movable magnetic plate 2 repel each other, increasing the gap between the lung body 4 and the thoracic cavity 3. The lung body 4 contracts to exhale gas, and the sterile gas in the auxiliary air sac 5 retracts to form an air bag 51 between the lung body 4 and the thoracic cavity 3. During the inspiratory phase, the fixed magnetic plate 1 and the movable magnetic plate 2 attract each other, decreasing the gap between the lung body 4 and the thoracic cavity 3. The lung body 4 expands to inhale gas, and the sterile gas in the auxiliary air sac 5 gathers at the apex of the lung body 4 to form a bubble 52. It should be noted that the lung capacity of a normal adult is approximately 2500 ml. For patients with obstructive pulmonary disease, the lung capacity is much smaller. The lung volume is significantly larger than normal, and the alveolar tissue on the outer surface of the lung body 4 is over-expanded and loses its normal function. Therefore, when a breathing assist bag 5 with a certain volume is implanted into the pleural cavity, it compresses the alveolar tissue on the surface of the lung body 4 that has lost its normal function due to over-expansion, forming something similar to a "small iatrogenic closed pneumothorax". However, it does not affect the airtightness of the pleural cavity or normal breathing. At the same time, the blood flow distribution at the apex of the lung is less than in other parts, and it is also easy to form bullae. Therefore, its actual respiratory function is significantly less than that of other parts of the lung. The air bubble 52 is placed in the apex of the lung, which can also minimize the impact of the air bubble 52 on lung function.

[0029] By setting up the auxiliary airbag 5, the fixed magnetic plate 1 and the movable magnetic plate 2 repel and attract each other, maintaining and coordinating the pressure balance in the thoracic cavity, thereby ensuring that the magnetic drive system can effectively assist breathing. Specifically, when the fixed magnetic plate 1 and the movable magnetic plate 2 repel each other, they compress the lung body 4 and contract. The gas in the auxiliary airbag 5 retracts to form an air bag 51 between the lung body 4 and the thoracic cavity 3. At this time, the volume of the auxiliary airbag 5 is larger than its volume in the resting state (equivalent to being stretched when the two magnetic plates repel each other). At this time, the gas in the lung body 4 is expelled from the body (i.e., exhalation). The flow of gas in the auxiliary airbag 5 helps to balance the pressure inside the lung body 4 and the air pressure outside the thoracic cavity 3. When the fixed magnetic plate 1 and the movable magnetic plate 2 attract each other, they pull the lung body 4 to expand, and the gas in the auxiliary airbag 5 gathers... Bubble 52 forms at the apex of the lung body 4. At this time, the volume of the auxiliary air sac 5 is smaller than its volume in the resting state (equivalent to being compressed when two magnetic plates are attracted to each other). The movement of gas within the auxiliary air sac 5 provides space for the expansion of the lung body 4, allowing the lung body 4 to inhale gas (i.e., inhalation), thereby regulating the balance between the internal pressure of the lung body 4 and the external air pressure. As a compressible and movable gas chamber, the auxiliary air sac 5 dynamically fills or creates space through the flow of sterile gas between the "air bag 51" and "bubble 52" forms. This ensures that the pressure between the surface of the lung body 4 and the inner wall of the thoracic cavity 3 remains relatively balanced when the magnetic plates are in motion, allowing the magnetic plates to smoothly pull or push the lung body 4 without causing the fixed magnetic plate 1 and the movable magnetic plate to become displaced. 2. Excessive auxiliary pressure or pull is a waste, used to counteract the negative pressure generated by the further retraction and expansion of the lung body 4. Furthermore, excessive auxiliary pressure or pull can damage lung tissue. That is, when the distance between the two magnetic plates is large in a repulsive state, the flow of sterile gas within the auxiliary air bladder 5 can relatively balance the pressure within the pleural cavity, ensuring its airtightness. This allows the auxiliary lung body 4 to retract and expand normally. Thus, when some chronic obstructive pulmonary diseases or respiratory infectious diseases cause external respiratory obstruction (i.e., the movement of the thoracic cage 3 is limited, unable to provide more volume space for the lung body 4; the contraction and contraction function of the thoracic cage 3 hinders the expansion of the lung body 4; or the movement of the thoracic cage 3 is normal but the lung expansion function is limited), the lung body 4 can expand normally. If the lung body 4 is unable to expand with the expansion of the thoracic cavity 3 due to impaired retraction or the force of lung body 4 recoil being greater than the force of lung body 4 expansion, it will ultimately lead to insufficient respiratory gas in the lung body 4, i.e., insufficient tidal volume. At the same time, the ratio of forced expiratory volume in one second (FEV1) to inspiratory volume in one second (FEI) will not reach the normal standard, thus manifesting as respiratory failure. When the assistive cuff 5 is implanted, it can assist the thoracic cavity 3. With the pleural cavity closed, it can maintain a relative pressure balance within the pleural cavity. When the fixed magnetic patch 1 and the movable magnetic patch 2 attract or repel each other, the pleural cavity will not be damaged. In this way, by actively compressing and pulling the lung body 4, the lung body 4 can achieve normal respiratory movement, restoring the normal tidal volume and FEV1 ratio, thereby achieving the goal of treating the patient's respiratory failure.

[0030] When the lung body 4 retracts, the sterile gas in the auxiliary air sac 5 flows back to the space between the lung body 4 and the thoracic cage 3 to form an air bag 51. When the lung body 4 expands, the sterile gas in the auxiliary air sac 5 compresses and flows to the apex of the lung body 4 to form a bubble 52. During inhalation, the fixed magnetic plate 1 and the movable magnetic plate 2 attract each other, and the movable magnetic plate 2 can pull the lung body 4 to expand, and the gap between the lung body 4 and the thoracic cage 3 becomes smaller. That is, the lung body 4 and the thoracic cage 3 compress the gas in the auxiliary air sac 5 to flow to the apex of the lung body 4 to form a bubble 52. Conversely, during exhalation, the fixed magnetic plate 1 and the movable magnetic plate 2 repel each other, and the movable magnetic plate 2 can compress the lung body 4 to contract, and the gap between the lung body 4 and the thoracic cage 3 becomes larger. That is, the gas in the bubble 52 in the auxiliary air sac 5 can flow back to the air bag 51 between the lung body 4 and the thoracic cage 3, thus completing one breathing cycle.

[0031] In summary, for patients with emphysema (inflation of the lung body 4, resulting in decreased recoil capacity) and lung-related infectious diseases, the procedure for implanting the assistive cuff 5 is as follows: First, based on the patient's (obstructive lung disease) body type (e.g., different heights, weights, etc., resulting in different lung volumes and required tidal volumes) and condition, determine the relevant parameters of the assistive cuff 5 (including size, internal sterile gas volume, and material), as well as the relevant parameters of the magnetic sheets (movable magnetic sheet 2 and fixed magnetic sheet 1) (including size and number). Specifically, the sterile gas volume inside the assistive cuff 5 is 10~700mL, and the fixed magnetic sheet 1... The repulsive distance L between magnetic sheet 1 and movable magnetic sheet 2 ranges from 0.3 to 7 cm. The respiratory rate X of the lung body 4 ranges from 12 to 18 breaths / min to increase the patient's tidal volume, so that the patient's lung body 4 has a ventilation rate of 6 to 9 L per minute. The patient (obstructive pulmonary disease) is under general anesthesia and double-lumen endotracheal intubation. During the operation, ventilation of the unilateral lung requiring the implantation of the respiratory assist device is reduced (while the other lung maintains normal breathing). The respiratory assist device is implanted into the pleural cavity through the 2nd, 3rd, 4th, 5th, 6th, or 7th intercostal space on the implantation side through a minimally invasive small incision thoracoscopic assistance. Specifically, a small incision is made... After making a small incision, the negative pressure in the pleural cavity decreases, the gas in the lung body 4 is expelled, and its volume shrinks to about 1 / 3 or less of its original volume. Then, the auxiliary airbag 5 can be placed between the lung body 4 and the thoracic cage 3 through the minimally invasive incision. One side of the auxiliary airbag 5 is fixed to the surface of the thoracic cage 3, and the other side is fixed to the surface of the lung body 4. The auxiliary airbag 5 and the magnetic sheet can be fixed using sutures or adhesive with good biocompatibility. Because the auxiliary airbag 5 and the two magnetic sheets are directly fixed to the surface of the lung body 4 and the thoracic cage 3, the auxiliary airbag 5, the surface of the thoracic cage 3, and the surface of the lung body 4 form a... As a whole, during the expansion and contraction of the lung body 4 and thoracic cavity 3, the auxiliary airbag 5 and the two magnetic plates will not slide relative to the surface of the lung body 4 and the thoracic cavity 3. Therefore, there is no problem of the lung body 4 failing to follow the expansion and contraction of the thoracic cavity 3 due to friction. At the same time, the breathing trigger 6 is fixed inside the thoracic cavity 3 or on the surface of the lung body 4, the parameter controller 7 is fixed inside the thoracic cavity 3, and finally the battery assembly 8 is fixed subcutaneously or externally. Similarly, the breathing assist device can be implanted in the other side of the thoracic cavity. After the operation, lung ventilation is restored, the gas in the pleural cavity is expelled, and finally the minimally invasive incision is sutured to restore the airtightness of the pleural cavity. Adjusting the parameter controller 7 to the spontaneous breathing trigger mode triggers changes in magnetic force according to the spontaneous breathing function (changing the displacement of the moving magnetic plate 2 and the fixed magnetic plate 1), thereby improving the forced inspiratory volume in one second and the forced expiratory volume in one second, increasing tidal volume and promoting the expulsion of residual volume, and effectively assisting patients with external respiratory dysfunction (such as emphysema, lung-related infectious diseases) in breathing.

[0032] Preferably, in practical applications, individual differences such as the patient's age, gender, height, weight, and health status will affect the expansion and contraction of the lung body 4 during respiration. In order to effectively assist breathing without causing discomfort or harm to the patient, further quantitative analysis is needed on the expansion and contraction of the lung body 4 during respiration. The parameter controller 7 is used to further record the repulsive distance L between the fixed magnetic sheet 1 and the movable magnetic sheet 2, and the respiratory rate X of the lung body 4 per minute. Before implanting the assistive cuff 5, the fixed magnetic sheet 1, and the movable magnetic sheet 2, it is necessary to test the two parameters, namely the repulsive distance L between the fixed magnetic sheet 1 and the movable magnetic sheet 2 and the respiratory rate X of the lung body 4, according to the patient's condition. Then, appropriate parameters for the assistive cuff 5, the fixed magnetic sheet 1, and the movable magnetic sheet 2 are selected based on these two parameters.

[0033] Preferably, for the calibration curve of the above-mentioned "LXY correspondence", the repulsive distance L between the fixed magnetic sheet 1 and the moving magnetic sheet 2 and the respiratory rate X per minute of the lung body 4 satisfy:

[0034]

[0035] Where Y is the minute ventilation of lung body 4 during respiration, that is, the minute ventilation of lung body 4 when the repulsive distance between fixed magnetic sheet 1 and moving magnetic sheet 2 is L, and the minute ventilation of lung body 4 is when the minute respiratory rate X is X. a, b, and c are fitting parameters.

[0036] The above is a simplified exponential function calculation model. In this model, the minute ventilation Y of the lung body 4 during breathing is taken as the function, and the distance L between the repulsion of the fixed magnetic sheet 1 and the moving magnetic sheet 2 and the minute respiratory rate X of the lung body 4 are taken as independent variables. That is, as L and X increase, the minute ventilation Y of the lung body 4 during breathing increases accordingly.

[0037] Therefore, it is assumed that if a patient's minute ventilation rate during respiration is under normal circumstances, then... (A normal adult's volume is approximately 6-9 liters), therefore, the following conditions must be met:

[0038]

[0039] That is: if At this time, the parameter controller 7 should be used for further adjustment to increase the repulsive distance L between the fixed magnet 1 and the moving magnet 2 and / or the respiratory rate X of the lung body 4 per minute, so as to increase the minute ventilation Y during breathing. Considering the device's tolerance, one of the repulsive distance L between the fixed magnet 1 and the movable magnet 2 and the respiratory rate X per minute of the lung body 4 can be adjusted separately as needed.

[0040] like At this time, the parameter controller 7 should be used for further adjustment to reduce the repulsive distance L between the fixed magnet 1 and the moving magnet 2 and / or the respiratory rate X of the lung body 4 per minute, so as to reduce the minute ventilation Y during breathing. Considering the device's tolerance, the distance between the fixed magnet 1 and the movable magnet 2 can be adjusted to either L or the respiratory rate X of the lung body 4 per minute, depending on the situation.

[0041] In summary, the parameter controller 7 can be used for programmed adjustment of the breathing mode, allowing for self-adjustment of the repulsive distance L between the fixed magnetic plate 1 and the moving magnetic plate 2, and the respiratory rate X per minute of the lung body 4, to provide more efficient assisted breathing. Furthermore, the breathing mode can be divided into a spontaneous breathing trigger mode and a fixed-frequency mode. When normal spontaneous breathing is present, the spontaneous breathing trigger mode is used to increase patient comfort. When the patient has no spontaneous breathing or suffers from sleep apnea syndrome, a suitable fixed-frequency mode can be selected to ensure normal breathing. Depending on the severity of the condition, the magnetic force can be adjusted, thereby adjusting the repulsive distance L between the fixed magnetic plate 1 and the moving magnetic plate 2, and the respiratory rate X per minute of the lung body 4, to achieve targeted changes in ventilation. During this process, an excessively high respiratory rate X may lead to respiratory muscle fatigue, thus affecting lung ventilation. Therefore, the respiratory rate X needs to be adjusted according to the patient's physiological condition and tolerance.

[0042] Example 2: Unlike Example 1, the movable magnetic sheet 2 can be a permanent magnet, while the fixed magnetic sheet 1, parameter controller 7, and battery assembly 8 can all be installed externally. In this way, the movable magnetic sheet 2, breathing trigger 6, and auxiliary airbag 5 can be surgically installed inside the body. Compared with Example 1, this greatly reduces the number of devices installed inside the body, which helps to improve safety and reduce the difficulty of surgery for doctors. It is also more convenient when some components need to be adjusted. However, compared with Example 1, its disadvantage is that because some components are external, the patient needs to carry them with him / her, and there will be some micro-incisions on the body depending on the situation, which is relatively easy to cause external infection.

[0043] This invention has been described through preferred embodiments. Those skilled in the art will understand that various changes or equivalent substitutions can be made to these features and embodiments without departing from the spirit and scope of the invention. This invention is not limited to the specific embodiments disclosed herein; other embodiments falling within the scope of the claims are also within the protection scope of this invention.

Claims

1. An implantable respiratory assist device, characterized in that: The system includes an auxiliary airbag (5), on both sides of which are fixed magnetic plates (1) and movable magnetic plates (2) that cooperate with each other. The auxiliary airbag (5) is located between the lung body (4) and the thorax (3). The fixed magnetic plates (1) are fixed on the thorax (3), and the movable magnetic plates (2) are fixed on the lung body (4). One side of the auxiliary airbag (5) is fixed on the surface of the thorax (3), and the other side is fixed on the surface of the lung body (4). The auxiliary airbag (5) is also filled with sterile gas. During the exhalation phase, the fixed magnetic sheet (1) and the movable magnetic sheet (2) repel each other, the gap between the lung body (4) and the thoracic cage (3) increases, the lung body (4) contracts and exhales gas, and the sterile gas in the auxiliary air bag (5) retracts to form an air bag (51) between the lung body (4) and the thoracic cage (3). During the inspiratory phase, the fixed magnetic sheet (1) and the movable magnetic sheet (2) attract each other, the gap between the lung body (4) and the thoracic cavity (3) decreases, the lung body (4) expands and inhales gas, and the sterile gas in the auxiliary air sac (5) gathers at the lung tip of the lung body (4) to form a bubble (52).

2. The implantable respiratory assist device according to claim 1, characterized in that: The volume of sterile gas inside the auxiliary airbag (5) is 10~700mL.

3. An implantable respiratory assist device according to claim 2, characterized in that: It also includes a breathing trigger (6) for sensing the breathing state and a parameter controller (7) for adjusting the breathing mode. The breathing trigger (6) is fixed on the surface of the lung body (4) or inside the thoracic cage (3), and the parameter controller (7) is fixed on the surface of the thoracic cage (3).

4. An implantable respiratory assist device according to claim 3, characterized in that: The fixed magnetic sheet (1) and the movable magnetic sheet (2) are also provided with a converter to switch the repulsive or attractive states of the fixed magnetic sheet (1) and the movable magnetic sheet (2).

5. An implantable respiratory assist device according to claim 4, characterized in that: It also includes a battery assembly (8), which is fixed to the surface of the thorax (3) to supply power to the components.

6. An implantable respiratory assist device according to claim 1, characterized in that: A plurality of external connection points (31) are uniformly arranged between the auxiliary airbag (5) and the surface of the thorax (3) to fix the auxiliary airbag (5) to the surface of the thorax (3). A plurality of internal connection points (41) are uniformly arranged between the auxiliary airbag (5) and the surface of the lung body (4) to fix the auxiliary airbag (5) to the surface of the lung body (4).

7. An implantable respiratory assist device according to claim 5, characterized in that: The parameter controller (7) is used to further record the repulsive distance between the fixed magnetic sheet (1) and the moving magnetic sheet (2) as L, and the respiratory rate of the lung body (4) as X, specifically including: The repulsive distance between the fixed magnetic sheet (1) and the movable magnetic sheet (2) is L, and the respiratory rate X per minute of the lung body (4) satisfies: Where Y is the ventilation per minute of the lung body (4) during respiration, that is, the distance between the repulsion of the fixed magnetic sheet (1) and the moving magnetic sheet (2) is L, the ventilation per minute of the lung body (4) during respiration when the respiratory rate X is X, and a, b, and c are fitting parameters.

8. An implantable respiratory assist device according to claim 7, characterized in that: The repulsion distance L between the fixed magnetic sheet (1) and the movable magnetic sheet (2) ranges from 0.3 to 7 cm, and the respiratory rate X of the lung body (4) ranges from 12 to 18 breaths / min.

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